ライフサイエンスコーパス: nonheme iron

1 w L1 doses, which partially depleted hepatic nonheme iron.

2 in humans, but the data have been limited to nonheme iron.

3 d further through the intestine than that of nonheme iron.

4 te that the rate of catalysis is enhanced by nonheme iron.

5 multimeric protein containing four atoms of nonheme iron.

6 HO(*), respectively, in the vicinity of the nonheme iron.

7 "meat factor" that stimulates absorption of nonheme iron.

8 role in promoting 2e- oxo atom transfer with nonheme iron.

9 of HO(*) at both the Mn4O5Ca cluster and the nonheme iron.

10 heme-iron absorption is greater than that of nonheme iron.

11 orbed via a mechanism different from that of nonheme iron.

12 <21 microg/L (n = 5), adapted to absorb less nonheme iron (3.2% at week 12 compared with 5.0% at week

13 detect any dependence of the NOS reaction on nonheme iron, a cofactor integral to catalysis in every

14 -containing porridge meal leads to decreased nonheme iron absorption and that a 1-h time interval bet

15 se are estimated from predictive algorithms, nonheme iron absorption from meals, and models of iron i

16 of a 1-h time interval of tea consumption on nonheme iron absorption in an iron-containing meal in a

17 Mammalian nonheme iron absorption requires reduction of dietary ir

18 a has been shown to be a potent inhibitor of nonheme iron absorption, but it remains unclear whether

19 he inhibitory effect, resulting in increased nonheme iron absorption.

20 Large variations were observed in mean nonheme-iron absorption (0.7-22.9%) between studies, whi

21 In premenopausal women, the efficiency of nonheme-iron absorption (P = 0.06, two-tailed test), but

22 of fruit, a dietary source of an enhancer of nonheme-iron absorption (vitamin C), promote high iron s

23 No significant relation was observed between nonheme-iron absorption and dietary factors known to inf

24 oux-en-Y gastric bypass (RYGBP) on heme- and nonheme-iron absorption and iron status.

25 domized, placebo-controlled trial, heme- and nonheme-iron absorption by healthy men and women (n = 57

26 We tested whether heme- and nonheme-iron absorption decrease in response to increase

27 Nonheme-iron absorption decreased from 11.1% to 4.7% (P

28 Radioisotopic measurements of nonheme-iron absorption from 25 meals were made in 86 vo

29 al was to examine the effect of vitamin C on nonheme-iron absorption from a complete diet rather than

30 This research indicates 1) 70% lower nonheme-iron absorption from a lactoovovegetarian diet t

31 lcium intake had no significant influence on nonheme-iron absorption from a varied diet.

32 The inhibiting effect of phytate on nonheme-iron absorption from different protein sources w

33 Heme- and nonheme-iron absorption from either high- or low-bioavai

34 even those with low iron stores, had reduced nonheme-iron absorption from food in response to iron su

35 Heme- and nonheme-iron absorption from whole diets were measured i

36 n the mucosal uptake and serosal transfer of nonheme-iron absorption in humans and the effects of cal

37 th serum hepcidin and serum prohepcidin with nonheme-iron absorption in the presence and absence of f

38 Nonheme-iron absorption was less from the lactoovovegeta

39 Nonheme-iron absorption was measured from the whole diet

40 Nonheme-iron absorption was measured in 14 healthy volun

41 Initially, both heme- and nonheme-iron absorption were inversely associated with s

42 om 58 individuals (all from US studies): log[nonheme-iron absorption, %] = -0.73 log[ferritin, mug/L]

43 the individual effects of dietary factors on nonheme-iron absorption, but their combined effect when

44 d total iron without significantly affecting nonheme-iron absorption, regardless of meal bioavailabil

45 etary, and hematologic indexes and heme- and nonheme-iron absorption-using a standardized meal contai

46 reported dietary inhibitor of both heme- and nonheme-iron absorption.

47 sal uptake was the primary control point for nonheme-iron absorption.

48 and ascorbic acid were useful for estimating nonheme-iron absorption.

49 lcium has a strongly inhibitory influence on nonheme-iron absorption.

50 ariations in calcium intake on total dietary nonheme-iron absorption.

51 oxidation reactions of organic substrates by nonheme iron activated species.

52 exes were designed specifically to mimic the nonheme iron active site of superoxide reductase, which

53 hydroxylase (MMOH) that contains a dinuclear nonheme iron active site; a reductase (MMOR) that facili

54 t involves a bifunctional thioesterase and a nonheme iron alpha-ketoglutarate-dependent enzyme.

55 We have identified a conserved group of nonheme iron, alpha-ketoglutarate-dependent oxygenases l

56 Three mononuclear nonheme iron and 2-oxoglutarate dependent enzymes, l-Ile

57 ated derivatives of l-glutamate catalyzed by nonheme iron and 2-oxoglutarate-dependent enzymes.

58 ions were associated with greater intakes of nonheme iron and ascorbic acid after control for age, BM

59 ted with greater intakes of foods containing nonheme iron and ascorbic acid.

60 ient mice, sla mouse enterocytes accumulated nonheme iron and ferritin.

61 Treatment with ethanol increased hepatic nonheme iron and hepatic 5-aminolevulinate synthase acti

62 absorption, storage, and cellular export of nonheme iron and in erythroblast uptake and utilization

63 processes in the case of mono- and dinuclear nonheme iron and manganese cofactors has remained largel

64 were applied to determine the 8-h uptake of nonheme iron and the 2-wk retention (absorption) of heme

65 ptake and the subsequent serosal transfer of nonheme iron and to determine the effects of adding calc

66 ailoring enzymes, including both mononuclear nonheme iron and two flavin-dependent halogenases, and a

67 ir diet models through the implementation of nonheme iron and zinc absorption equations using either

68 ing diet models with nonlinear equations for nonheme iron and zinc absorption.

69 he accuracy of the calculation of absorbable nonheme iron and zinc content in diet-model-generated me

70 et of cofactors that typically include heme, nonheme iron, and copper.

71 ar active sites containing heme/copper, heme/nonheme iron, and heme-[4Fe-4S] centers, respectively.

72 in a model that contained dietary heme iron, nonheme iron, and zinc intakes, dietary heme iron showed

73 n of such a species in the mechanisms of the nonheme iron- and pterin-dependent aryl amino acid hydro

74 nase (HpxE-HpxD enzyme) homologous to Rieske nonheme iron aromatic-ring-hydroxylating systems, such a

75 ed as important intermediates in a number of nonheme iron as well as heme-containing enzymes, yet the

76 Absorption of nonheme iron assessed in the presence (P = 0.038) and ab

77 d as a monomer of M(r) 28,000 that contained nonheme iron at 2.05 +/- 0.34 mol of Fe per FNR monomer.

78 oor man's B(12)), or very small, such as one nonheme iron atom coordinated by protein ligands.

79 de (FMN) the homologs contained six to eight nonheme iron atoms and 1.6 to 1.7 FMN molecules per dime

80 Herein, the nonheme iron-based 3-hydroxyanthranilate-3,4-dioxygenase

81 Pirin is a nonheme iron-binding protein with a variety of proposed

82 Nonheme iron bioavailability was determined from 2-wk re

83 hown that many dietary factors can influence nonheme-iron bioavailability.

84 ly with the initial uptake and absorption of nonheme iron, but not with the nonheme serosal transfer

85 We measured membrane nonheme iron by its reactivity with ferrozine.

86 The meal contents of nonheme iron, calcium, ascorbic acid, polyphenols, and p

87 d lending credence to proposed mechanisms of nonheme iron catalysis.

88 '',2''''-quinquepyridine) is a highly active nonheme iron catalyst for intra- and intermolecular amin

89 Hydrocarbon oxidations by bio-inspired nonheme iron catalysts and H2O2 have been proposed to in

90 ating Rieske dioxygenases and of bioinspired nonheme iron catalysts for alkane hydroxylation, olefin

91 ske-type [2Fe-2S] center and one mononuclear nonheme iron center in each large oxygenase subunit.

92 roups in the second coordination sphere of a nonheme iron center is reported.

93 s into the active site of RPE65 close to the nonheme iron center.

94 bit two distinct biological functions with a nonheme iron center.

95 an generate and release HNO, suggesting that nonheme iron centers could be endogenous or exogenous so

96 haKG)-dependent dioxygenases use mononuclear nonheme iron centers to effect hydroxylation of their su

97 of secondary coordination sphere effects at nonheme iron centers.

98 1] epoxidase (HppE) reduces H(2)O(2) at its nonheme-iron cofactor to install the oxirane "warhead" o

99 A nonheme iron complex bearing the tris(6-phenylamino-pyri

100 These results show that a nonheme iron complex can generate and release HNO, sugge

101 providing the first example of a mononuclear nonheme iron complex that is capable of converting NO to

102 The nonheme iron complex, [Fe(NO)(N3PyS)]BF4, is a rare exam

103 A new alkylthiolate-ligated nonheme iron complex, Fe(II)(BNPA(Me2)S)Br (1), is repor

104 The new nonheme iron complexes Fe(II)(BNPA(Ph2)O)(N(3)) (1), Fe(

105 y of the family of Rieske oxygenase enzymes, nonheme iron complexes of tetradentate N4 ligands have b

106 OOH intermediate, which is unprecedented for nonheme iron complexes supported by neutral pentadentate

107 is and reactivity of a series of mononuclear nonheme iron complexes that carry out intramolecular aro

108 2) binding and activation at weakly reducing nonheme iron complexes, highlighting a cooperative role

109 fects on hepatic ferritin subunit levels and nonheme iron concentration.

110 hepatic ferritin subunit levels and hepatic nonheme iron concentration.

111 Lipoxygenases (LOXs) are monomeric, nonheme iron-containing dioxygenases that initiate the f

112 Methane monooxygenase (MMO) is a nonheme iron-containing enzyme which consists of three p

113 Superoxide reductases (SORs) are nonheme iron-containing enzymes that reduce HO(2) to H(2

114 -His-1-Glu metal center, as found in natural nonheme iron-containing enzymes, was engineered into spe

115 a protein that has significant homology to a nonheme iron-containing ferritin protein from Listeria i

116 iron in other streptococci is that encoding nonheme iron-containing ferritin, dpr, but previous atte

117 both normal and Hfe knock-out mice, duodenal nonheme iron content was found to correlate with liver i

118 Determination of acid-labile sulfur and nonheme iron demonstrated that there is one [2Fe-2S] clu

119 rsenic resistance (ars) operon and encodes a nonheme iron-dependent dioxygenase with C As lyase activ

120 Memo and show it be homologous to class III nonheme iron-dependent dioxygenases, a structural class

121 enesis studies indicate that OzmD is a novel nonheme iron-dependent enzyme in which the catalytic iro

122 Many nonheme iron-dependent enzymes activate dioxygen to cata

123 sults appear to connect NOS to the known H4B/nonheme iron-dependent hydroxylases, and suggest a simil

124 terminal olefins using an oxygen-activating, nonheme iron-dependent mechanism.

125 est family of RiPPs modified by multinuclear nonheme iron-dependent oxidases (MNIO, DUF692 family).

126 The multinuclear nonheme iron-dependent oxidases (MNIOs) are a rapidly gr

127 Multinuclear nonheme iron-dependent oxidative enzymes (MNIOs, previou

128 terocyclization reactions catalyzed by other nonheme iron-dependent oxygenase-like enzymes, such as i

129 tochrome P450 monooxygenase, a hydroxylating nonheme-iron-dependent dioxygenase, and an ABM family mo

130 d glomerular renal injury was accompanied by nonheme iron deposition and hypoxia-inducible factor-1al

131 s in serosal transfer indicate that heme and nonheme iron did not enter a common absorptive pool with

132 Prolyl 4-hydroxylase (P4H) is a nonheme iron dioxygenase that catalyzes the posttranslat

133 Because aromatic dioxygenation by nonheme iron dioxygenases is frequently the initial step

134 The lipoxygenases (LOs) are a family of nonheme iron dioxygenases that catalyse the insertion of

135 o bifunctional alpha-ketoglutarate-dependent nonheme iron dioxygenases, SwnH2 and SwnH1, along with a

136 Our study focused on nonheme iron distribution and the expression of the iron

137 1, possibly via delivery or reduction of the nonheme iron during PSII assembly.

138 functional models of the active site of the nonheme iron enzyme cysteine dioxygenase (CDO) is report

139 step of the catalytic cycle of the binuclear nonheme iron enzyme Delta(9) desaturase.

140 he reactive mononitrosyl intermediate in the nonheme iron enzyme FDPnor (v(NO)=1681 cm(-1) ).

141 n C synthase (DAOCS) is an alphaKG-dependent nonheme iron enzyme for which both of these mechanisms h

142 Specifically, we demonstrate that the nonheme iron enzyme isopenicillin N synthase (IPNS) from

143 The nonheme iron enzyme phenylalanine hydroxylase, tyrosine

144 UndA is a nonheme iron enzyme that activates oxygen to catalyze th

145 se (PAH) is a tetrahydrobiopterin-dependent, nonheme iron enzyme that catalyzes the hydroxylation of

146 osine hydroxylase (TH) is a pterin-dependent nonheme iron enzyme that catalyzes the hydroxylation of

147 te (3MPA) dioxygenase (MDO) is a mononuclear nonheme iron enzyme that catalyzes the O(2)-dependent ox

148 (ACCO), an O2-activating ascorbate-dependent nonheme iron enzyme, catalyzes the last step in ethylene

149 In this work, we demonstrate that a nonheme iron enzyme, hydroxymandelate synthase from Amyc

150 ase from Amycolatopsis orientalis (AoHMS), a nonheme iron enzyme.

151 eaving step in the activation of dioxygen by nonheme iron enzymes and in the first step of the Fenton

152 chaperones to multiple classes of cytosolic nonheme iron enzymes and may have a particular role in r

153 High-valent intermediates of binuclear nonheme iron enzymes are structurally unknown despite th

154 itute a new enzyme family in contrast to the nonheme iron enzymes for DOPA production.

155 s the immense potential of metal-substituted nonheme iron enzymes for evolving new-to-nature transfor

156 Nonheme iron enzymes generate powerful and versatile oxi

157 re relevant to the activation of dioxygen by nonheme iron enzymes have been generated from synthetic

158 XES for identifying intermediate species in nonheme iron enzymes is highlighted.

159 In contrast, engineering mononuclear nonheme iron enzymes is lagging, even though these enzym

160 Nonheme iron enzymes rank among nature's most versatile

161 Sulfoxide synthases are nonheme iron enzymes that catalyze oxidative carbon-sulf

162 synthase EgtB represents a unique family of nonheme iron enzymes that catalyze the formation of a C-

163 enases are a catalytically diverse family of nonheme iron enzymes that oxidize their primary substrat

164 We report the reprogramming of nonheme iron enzymes to catalyze an abiological C(sp(3))

165 In this study, we repurposed nonheme iron enzymes to generate iron nitrene intermedia

166 In nature, nonheme iron enzymes use dioxygen to generate high-spin

167 Nonheme iron enzymes utilize S = 2 iron(IV)-oxo intermed

168 a class of substrate activating mononuclear nonheme iron enzymes which catalyze the hydroperoxidatio

169 the alpha-ketoglutarate (alphaKG)-dependent nonheme iron enzymes, both a concerted mechanism (both c

170 nsidered in the context of another family of nonheme iron enzymes, the nitrile hydratases, in which p

171 ns in organic synthesis and the diversity of nonheme iron enzymes, we envision that this discovery wi

172 Similar studies can be performed for other nonheme iron enzymes, with the 18O KIEs providing a kine

173 s operative in DAOCS and by extension, other nonheme iron enzymes.

174 tic strategy established for O(2)-activating nonheme iron enzymes.

175 en activation mechanisms of many mononuclear nonheme iron enzymes.

176 usive radical "rebound" process proposed for nonheme iron enzymes.

177 on oxidation of substrates proposed for some nonheme iron enzymes.

178 as been made in designing heme and dinuclear nonheme iron enzymes.

179 gh-valent oxo intermediates in the binuclear nonheme iron enzymes.

180 e key intermediates in the catalysis of most nonheme iron enzymes.

181 valent oxoiron(IV) intermediates observed in nonheme iron enzymes.

182 molecular basis of epoxidation catalyzed by nonheme-iron enzymes is much less explored.

183 nate was absent from its binding site on the nonheme iron (Fe(2+)) and the addition of bicarbonate or

184 s more bioavailable and better absorbed than nonheme iron found in plants.

185 The structures of nonheme iron-free and di-Fe(2+) forms of BFR showed that

186 We compared the absorption of heme and nonheme iron from minimally or highly fortified test mea

187 bjects in their absorption of either heme or nonheme iron from minimally or highly fortified test mea

188 A member of the nonheme iron group of dietary iron sources, ferritin is

189 halogenase for piperazate) is a mononuclear nonheme iron halogenase that acts on the piperazyl ring

190 ytC3 with the closed conformation of another nonheme iron halogenase, SyrB2, suggests two important c

191 Nonheme iron halogenases are unique enzymes in nature th

192 ze the expression of iron-related genes, (2) nonheme iron histochemistry, (3) immunohistochemistry fo

193 ous to the proposed radical rebound step for nonheme iron hydroxylases and halogenases.

194 The analogous Fe(III)(OH) intermediate in nonheme iron hydroxylases transfers OH(*) to give alcoho

195 amily and expand the catalytic repertoire of nonheme iron hydroxylases.

196 Mononuclear nonheme iron(II) and 2-oxoglutarate (Fe/2OG)-dependent o

197 mple of dioxygen activation at a mononuclear nonheme iron(II) complex that produces both Fe(III)-O-O-

198 A new nonheme iron(II) complex, Fe(II) (Me(3) TACN)((OSi(Ph2)

199 tailed study on epoxidation catalyzed by the nonheme iron(II)- and 2-oxoglutarate-dependent (Fe/2OG)

200 a short-chain dehydrogenase/reductase and a nonheme iron(II)- and 2-oxoglutarate-dependent oxygenase

201 hydroxylation is favored over azidation for nonheme iron(III) complexes, but the nature of the carbo

202 example of a mononuclear low-spin (S = 1/2) nonheme iron(III)-alkylperoxo complex displaying such un

203 acetonitrile to generate a thiolate-ligated, nonheme iron(III)-nitro complex, [Fe(III)(NO2)(N3PyS)](+

204 philic reactivity correlation of mononuclear nonheme iron(III)-peroxo complexes bearing N-tetramethyl

205 the 2-wk retention (absorption) of heme and nonheme iron in healthy adults (n = 17) after the consum

206 The increases in nonheme iron in Hfe(-/-) mice were associated with diffu

207 Soybeans are a major source of nonheme iron in many human diets, but information on iro

208 244)Y, which is a bicarbonate ligand for the nonheme iron, induces the propagation of oxidative react

209 er factors, women in the highest quintile of nonheme iron intake had a relative risk of PMS of 0.64 (

210 wth and suggests the possible existence of a nonheme, iron-involving EET process in cathodic mode.

211 Bioavailability of nonheme iron is influenced by the concentration of inhib

212 bsorption of heme iron is poorly understood, nonheme iron is transported across the apical membrane o

213 nce in reactivity and chemical properties of nonheme iron(IV)-oxo compared with iron(IV)-tosylimido.

214 X = H (3), and X = CF3 (4)) promoted by the nonheme iron(IV)-oxo complex [(N4Py)Fe(IV) horizontal li

215 oxidation of a series of hydrocarbons by the nonheme iron(IV)-oxo complex [(N4Py)Fe(IV)=O](2+) is eff

216 ethyl-1-phenylethyl sulfides promoted by the nonheme iron(IV)-oxo complexes [(N4Py)Fe(IV) horizontal

217 iron(IV)-oxo oxidants that include heme and nonheme iron(IV)-oxo oxidants.

218 Mean membrane nonheme iron levels were higher in hemoglobin SS cells t

219 epletion and an increase in serum and kidney nonheme iron levels.

220 Superoxide reductase is a nonheme iron metalloenzyme that detoxifies superoxide an

221 and NdmB are actually two independent Rieske nonheme iron monooxygenases with N(1)- and N(3)-specific

222 ion associated with hemochromatosis absorbed nonheme iron more efficiently than did control subjects

223 Hepatic nonheme iron (NHFe) and hepatocyte iron staining were no

224 c structure determination is the first for a nonheme iron nitroxyl {FeNO}(8) and has allowed to ident

225 Isopenicillin N synthase (IPNS) is a nonheme iron oxidase that catalyzes the central step in

226 ta-hydroxylase (H6H) is an alphaKG-dependent nonheme iron oxidase that catalyzes the oxidation of hyo

227 for the design of regio- and stereospecific nonheme iron oxidation catalysts but also for providing

228 ses of arylsulfides and benzyl alcohols by a nonheme iron-oxo complex have been studied.

229 Myohemerythrin (Mhr) is a nonheme iron oxygen carrier found in the retractor muscl

230 nks to the design of cross-linked artificial nonheme iron oxygenase crystals, we filled this gap by d

231 erium Sphingomonas paucimobilis TMY1009 is a nonheme iron oxygenase that catalyzes the cleavage of li

232 ic cancer drug streptozotocin, the tridomain nonheme-iron oxygenase SznF hydroxylates N(d) and N(w)'

233 )=O centers generated in the active sites of nonheme iron oxygenases cleave substrate C-H bonds at ra

234 Rieske nonheme iron oxygenases form a large class of aromatic r

235 D) and methylphosphonate synthase (MPnS) are nonheme iron oxygenases that both catalyze the carbon-ca

236 Nonheme iron oxygenases that carry out four-electron oxi

237 Thiol dioxygenases are a subset of nonheme iron oxygenases that catalyze the formation of s

238 omes encode a family of structurally related nonheme iron oxygenases that modify double bonds of thes

239 phic studies of NDO and other related Rieske nonheme iron oxygenases to develop molecular level insig

240 Nonheme iron oxygenases utilize dioxygen to accomplish c

241 es are often implicated in the mechanisms of nonheme iron oxygenases, their C-H bond cleaving propert

242 died alpha-ketoglutarate (alphaKG)-dependent nonheme iron oxygenases.

243 e prepared as models for the active sites of nonheme iron oxygenases.

244 the alpha-ketoglutarate (alpha-KG)-dependent nonheme iron oxygenases.

245 igand, similar to that proposed for numerous nonheme iron oxygenases.

246 ured for two recently discovered mononuclear nonheme iron oxygenases: hydroxyethylphosphonate dioxyge

247 T. molitor iron is absorbed from the common nonheme iron pool.

248 intakes, but not higher intakes of heme and nonheme iron, predicted a lower risk of low hemoglobin a

249 Rubrerythrin is a nonheme iron protein of unknown function isolated from D

250 A five-gene cluster encoding four nonheme iron proteins and a flavoprotein from the thermo

251 and transfer reactions mediated by heme and nonheme iron proteins and the interactions of amphiphili

252 ythrins (Hrs) and myohemerythrins (Mhrs) are nonheme iron proteins that function as O2 carriers in fo

253 site is similar to several other mononuclear nonheme iron proteins, including naphthalene dioxygenase

254 This alternative system consists of the nonheme iron proteins, rubrerythrin (Rbr) and rubredoxin

255 The wide range of nonheme iron receptors matched to the structure of the i

256 f adding calcium to a meal on both heme- and nonheme-iron retention.

257 iron showed a positive association, dietary nonheme iron showed a U-shaped association, and dietary

258 aptopropionic acid (3MPA) coordinates to the nonheme iron site in 3MDO remains a matter of debate.

259 of chemical and biological properties among nonheme iron sources.

260 absorption from supplemental and food-based nonheme-iron sources in iron-replete healthy women.

261 stitutes the first example where a synthetic nonheme iron species responsible for stereospecific and

262 iron-loaded macrophages and elevated hepatic nonheme iron stores.

263 MER was used to introduce the active site of nonheme iron superoxide dismutase (SOD) into the hydroph

264 This first example of a nonheme iron-superoxo intermediate exhibits the highest

265 athways that can be accessed by bio-inspired nonheme iron systems to form the high-valent iron-oxo in

266 Two-thirds of the nonheme iron taken up by the mucosa within 8 h was retai

267 forms of chaperone proteins, including, for nonheme iron, the transport protein transferrin and the

268 major regulator of transferrin-independent, nonheme iron uptake.

269 hydrogen that is bonded to Pheo(D1) and the nonheme iron (via bicarbonate), and thus protects electr

270 Because absorption of nonheme iron was not substantially greater in pregnant w

271 trend = 0.04); corresponding RRs for dietary nonheme iron were 1.0, 0.93, 0.63, 0.83, and 1.20 (P for

272 The initial uptake and absorption of nonheme iron were 11% and 7%, respectively, and the abso

273 The concentrations of total and nonheme iron were also increased in the lavage fluid of

274 nhancing effect on the absorption of dietary nonheme iron when assessed by feeding single meals to fa

275 Its cleavage occurs in the vicinity of a nonheme iron which binds to PSII on its electron accepto

276 n attributed to the local diet consisting of nonheme iron, which has lower absorption than that of he

277 s were found to have severe malabsorption of nonheme iron, which persisted after the development of I

278 to compare the serosal transfer of heme and nonheme iron, which should not differ if the 2 forms hav

279 ptake (8 h) and retention (2 wk) of heme and nonheme iron with and without a calcium supplement (450

280 er consuming an iron supplement, a source of nonheme iron, with a meal containing animal meat once a

281 ocopherol is localized near Pheo(D1) and the nonheme iron, with its chromanol head exposed to the lip