ライフサイエンスコーパス: nonhomologous

1 en recombination occurs without a protruding nonhomologous 3' tail, the mismatch repair protein Msh2

2 accharomyces cerevisiae is determined by two nonhomologous alleles, MATa and MATalpha.

3 equent sequence comparison showed that these nonhomologous allergens contained several similar surfac

4 of the IgE to these specific homologous and nonhomologous allergens was corroborated in an animal mo

5 e demonstrate that regulatory "switching" to nonhomologous alternatives is ubiquitous, occurring acro

6 We also found that nonhomologous centromeres are clustered during this proc

7 the clustering and pairwise associations of nonhomologous centromeres that precede stable pairing be

8 Data Bank and identify several sequentially nonhomologous chains that form a Hopf link and a Solomon

9 ere pairing early in meiosis I, even between nonhomologous chromosomes, and clustering of centromeres

10 ly repetitive arrays that are similar across nonhomologous chromosomes.

11 to pair and instead remained associated with nonhomologous chromosomes.

12 conservation (e.g., mobile gene clusters and nonhomologous cluster alleles), our approach also implic

13 different alleles corresponded to distinct, nonhomologous clusters; and location polymorphisms, in w

14 man pathogenic CNVs and the subset of larger nonhomologous constitutional CNVs.

15 the ligase IV complex that is central to the nonhomologous DNA end joining (NHEJ) pathway, this raise

16 epaired by homologous recombination (HR) and nonhomologous DNA end joining (NHEJ).

17 4 in regulating homologous recombination and nonhomologous DNA end joining-mediated DSB repair in hum

18 making it relevant to the role of ARTEMIS in nonhomologous DNA end joining.

19 The classical nonhomologous DNA end-joining (C-NHEJ) double-strand bre

20 Classical nonhomologous DNA end-joining (C-NHEJ), which is a major

21 In humans, nonhomologous DNA end-joining (NHEJ) is the major pathwa

22 Nonhomologous DNA end-joining (NHEJ) is the predominant

23 The nonhomologous DNA end-joining (NHEJ) pathway is a key me

24 Moreover, Red1 exhibited nonhomologous DNA end-joining activity, thus revealing a

25 We now show that knockdown of alt-nonhomologous end joining (alt-NHEJ) components-XRCC1, L

26 ated a poorly defined alternative pathway of nonhomologous end joining (alt-NHEJ) in the generation o

27 ombination (HR) and classical or alternative nonhomologous end joining (C-NHEJ versus A-EJ).

28 Classical nonhomologous end joining (C-NHEJ) is a major mammalian

29 Classical nonhomologous end joining (C-NHEJ) is a major mammalian

30 end-joining (EJ) repair pathways [canonical nonhomologous end joining (C-NHEJ) or alternative end jo

31 double-strand break repair via the canonical nonhomologous end joining (c-NHEJ) pathway.

32 oining of DSBs within S regions by classical nonhomologous end joining (C-NHEJ).

33 most small deletions occur during classical nonhomologous end joining (C-NHEJ).

34 predominantly by classical, DNA-PK-dependent nonhomologous end joining (D-NHEJ).

35 e/phosphatase-like factor (APLF) facilitates nonhomologous end joining (NHEJ) and associates with the

36 posure, which is indicative of activation of nonhomologous end joining (NHEJ) and homologous recombin

37 nd breaks are repaired by two main pathways: nonhomologous end joining (NHEJ) and homologous recombin

38 How a cell chooses between nonhomologous end joining (NHEJ) and homologous recombin

39 Cells use two major pathways for DSB repair: nonhomologous end joining (NHEJ) and homologous recombin

40 ables the generation of knockout alleles via nonhomologous end joining (NHEJ) and knock-in alleles vi

41 rossovers while alternative pathways such as nonhomologous end joining (NHEJ) are suppressed.

42 Homologous recombination (HR) and nonhomologous end joining (NHEJ) are two distinct DNA do

43 s used to repair DNA double-strand breaks by nonhomologous end joining (NHEJ) are two related family

44 Nonhomologous end joining (NHEJ) can effectively resolve

45 We previously showed that the lack of nonhomologous end joining (NHEJ) DNA repair factor ligas

46 between classical (c)- and alternative (alt)-nonhomologous end joining (NHEJ) during DNA double-stran

47 ter assay, we found that COH29 could inhibit nonhomologous end joining (NHEJ) efficiency and that no

48 BRCA1, and deletion of Rif1 suppresses toxic nonhomologous end joining (NHEJ) induced by PARP inhibit

49 Nonhomologous end joining (NHEJ) is a recently described

50 Nonhomologous end joining (NHEJ) is essential for effici

51 by either homology-directed repair (HDR) or nonhomologous end joining (NHEJ) is tightly regulated.

52 Subsequently, nonhomologous end joining (NHEJ) opens, processes, and f

53 double-strand breaks (DSBs) are repaired by nonhomologous end joining (NHEJ) or homologous recombina

54 f tools for Cas9-mediated genome editing via nonhomologous end joining (NHEJ) or homology-directed re

55 Transcriptional up-regulation of major nonhomologous end joining (NHEJ) pathway genes KU80, X-R

56 DR) mechanisms: the dominant but error-prone nonhomologous end joining (NHEJ) pathway, and the less-f

57 in mre-11(iow1) mutants are repaired by the nonhomologous end joining (NHEJ) pathway, as removing NH

58 A breaks are ultimately resolved through the nonhomologous end joining (NHEJ) pathway.

59 ation repair and antagonizes 53BP1-dependent nonhomologous end joining (NHEJ) pathway.

60 r of double strand breaks (DSBs) through the nonhomologous end joining (NHEJ) pathway.

61 lso suppress inappropriate activation of the nonhomologous end joining (NHEJ) pathway.

62 SET-transposase fusion protein that promotes nonhomologous end joining (NHEJ) repair in humans.

63 primase/polymerase (PolDom) is required for nonhomologous end joining (NHEJ) repair of DNA double-st

64 NA-dependent protein kinase (DNA-PK) and the nonhomologous end joining (NHEJ) repair pathway are intr

65 omote KSHV replication, proteins involved in nonhomologous end joining (NHEJ) repair restrict amplifi

66 of the DNA-PK enzyme, which are involved in nonhomologous end joining (NHEJ) repair, enhance amplifi

67 Nonhomologous end joining (NHEJ) repairs chromosome brea

68 kinase substrates and stimulates error-prone nonhomologous end joining (NHEJ) selectively in HR-defic

69 Many bacteria rely on nonhomologous end joining (NHEJ) when only a single copy

70 Nonhomologous end joining (NHEJ), a major pathway of DNA

71 he efficiency of these methods is limited by nonhomologous end joining (NHEJ), an alternative DNA rep

72 pair systems: homologous recombination (HR), nonhomologous end joining (NHEJ), and single-strand anne

73 ntify DNA-PKcs complex proteins that mediate nonhomologous end joining (NHEJ), as TRIP13-binding part

74 knockout cells and organisms via error-prone nonhomologous end joining (NHEJ), but the efficiency of

75 on, which is almost exclusively dependent on nonhomologous end joining (NHEJ), CSR can occur in NHEJ-

76 ocalized sequence changes through inaccurate nonhomologous end joining (NHEJ), often leading to gene

77 subunit (DNA-PKcs) is a central component of nonhomologous end joining (NHEJ), repairing DNA double-s

78 nation (HR) but can inhibit normal repair by nonhomologous end joining (NHEJ), the main DSB repair pa

79 aired both homologous recombination (HR) and nonhomologous end joining (NHEJ), the two major DSB repa

80 early phosphorylations promote initiation of nonhomologous end joining (NHEJ), whereas ABCDE phosphor

81 ency and decreased accuracy of DSB repair by nonhomologous end joining (NHEJ), which is required for

82 Collectively, the data define a nonhomologous end joining (NHEJ)-independent, S-phase-sp

83 Nonhomologous end joining (NHEJ)-mediated repair of DSBs

84 ct DNA ends from resection and thereby favor nonhomologous end joining (NHEJ).

85 epaired via homologous recombination (HR) or nonhomologous end joining (NHEJ).

86 r, increasing the involvement of error-prone nonhomologous end joining (NHEJ).

87 Bs) and their adequate recombination through nonhomologous end joining (NHEJ).

88 pathways: homology-directed repair (HDR) or nonhomologous end joining (NHEJ).

89 ed in telomere maintenance and DNA repair by nonhomologous end joining (NHEJ).

90 er a novel role for PARylation in regulating nonhomologous end joining (NHEJ).

91 ensitivity is rescued by the inactivation of nonhomologous end joining (NHEJ).

92 capacity for classical, versus alternative, nonhomologous end joining (NHEJ).

93 r: the homologous recombination (HR) and the nonhomologous end joining (NHEJ).

94 B by either homologous recombination (HR) or nonhomologous end joining (NHEJ).

95 d DNA double-stranded break (DSB) repair via nonhomologous end joining and homologous recombination.

96 SBs) and stimulates DSB repair, through both nonhomologous end joining and homologous recombination.

97 volved in DNA replication and repair by both nonhomologous end joining and homologous repair is misre

98 break produced by Ac excision: footprints by nonhomologous end joining and rearrangements by various

99 atures of the fusion fragments indicate that nonhomologous end joining and/or replication-dependent D

100 t the level of 10-20% of HR when both HR and nonhomologous end joining are available.

101 tropicalis induced mutations consistent with nonhomologous end joining at the target site, resulting

102 S-S junctions are joined via a nonhomologous end joining DNA repair process.

103 active cell cycle checkpoints and increased nonhomologous end joining DNA repair, suggesting that pe

104 nase catalytic subunit (DNA-PKcs), a classic nonhomologous end joining factor, antagonizes double str

105 One of the major DSBs repair pathways is nonhomologous end joining for which Ku70/80 is essential

106 es four broken DNA ends that are repaired by nonhomologous end joining forming coding and signal join

107 Yet, how XLF binds XRCC4 and impacts nonhomologous end joining functions has been enigmatic.

108 was an indirect effect of the repression of nonhomologous end joining in Sir(-) mutants and that the

109 Specifically, nonhomologous end joining is the predominant mechanism u

110 Nonhomologous end joining is the primary deoxyribonuclei

111 Finally, we demonstrate that nonhomologous end joining is uniquely required for the d

112 uence analysis suggested fundamental role of nonhomologous end joining mechanism during eccDNA format

113 Cas9 lesions by homologous recombination or nonhomologous end joining mechanisms can lead to the int

114 he integrity of homology-directed repair and nonhomologous end joining of DNA breaks is impaired in K

115 Several of these genes are also involved in nonhomologous end joining of DNA double-strand break rep

116 breaks (DSBs) are generally repaired through nonhomologous end joining or homologous recombination.

117 ble-strand breaks that stimulate error-prone nonhomologous end joining or homology-directed repair at

118 ts must be removed to allow repair by either nonhomologous end joining or homology-directed repair.

119 ecombination but instead form most often via nonhomologous end joining or microhomology-mediated brea

120 mediates inhibition of the DNA-PK-dependent nonhomologous end joining pathway contributing to the ac

121 genetic disruption strategies relying on the nonhomologous end joining pathway may induce compensator

122 rm of DNA damage, are mainly repaired by the nonhomologous end joining pathway, which relies on DNA-P

123 and an increase in repair by the alternative nonhomologous end joining pathway.

124 ltaAID is impaired in its ability to recruit nonhomologous end joining repair factors, resulting in a

125 n inhibitor of the DNA-PK kinase crucial for nonhomologous end joining repair of DNA DSBs, and BRCA2-

126 Double strand breaks may trigger nonhomologous end joining repair, leading to frameshift

127 s in CML progenitors was mediated by classic nonhomologous end joining repair.

128 Nonhomologous end joining repairs DNA double-strand brea

129 ly triggers an activation of the error-prone nonhomologous end joining response.

130 also find that MMEJ compensates for loss of nonhomologous end joining to repair rereplication DSBs i

131 ated homologous recombination and restrained nonhomologous end joining, affecting cell survival after

132 lar domain, including Tel1 (ATM) activation, nonhomologous end joining, and DNA double-strand break e

133 s switch recombination, two events requiring nonhomologous end joining, at levels comparable to Atm(-

134 uggests that, in addition to its key role in nonhomologous end joining, DNA-PKcs also acts in concert

135 pair, mismatch repair, base excision repair, nonhomologous end joining, homologous recombination, and

136 In nonhomologous end joining, Ku loads onto broken DNA via

137 e Ku heterodimer complex, which functions in nonhomologous end joining, mediates clustering of long t

138 d that, distinct from Ku-dependent classical nonhomologous end joining, MMEJ--even with very limited

139 smatch, nucleotide excision, Fanconi anemia, nonhomologous end joining, or translesion synthesis repa

140 sis during DNA double strand break repair by nonhomologous end joining, particularly in nonreplicatin

141 factor (XLF)-XRCC4 complex is essential for nonhomologous end joining, the major repair pathway for

142 major pathway for Ku-independent alternative nonhomologous end joining, which contributes to chromoso

143 ithin a population, which typically arise by nonhomologous end joining.

144 imulate DNA double-strand break ligation via nonhomologous end joining.

145 insertions/deletions (indels) via mutagenic nonhomologous end joining.

146 by directly binding and activating DNA-PK in nonhomologous end joining.

147 ogical functions in base excision repair and nonhomologous end joining.

148 stant, repairing DNA double-strand breaks by nonhomologous end joining.

149 n DSBs toward accurate and efficient CSR via nonhomologous end joining.

150 that XRCC1 also participates in alternative nonhomologous end joining.

151 mage accumulation, with a repair bias toward nonhomologous end joining.

152 l components of the error-prone, alternative nonhomologous end-joining (alt-NHEJ) pathway.

153 Classical nonhomologous end-joining (C-NHEJ) and alternative end-j

154 The classic nonhomologous end-joining (c-NHEJ) pathway is largely re

155 translocations in wild-type versus classical nonhomologous end-joining (C-NHEJ)-deficient NSPCs revea

156 at are initiated on free DNA ends: classical nonhomologous end-joining (NHEJ) and ATM-dependent DNA d

157 DNA damage, functioning as part of both the nonhomologous end-joining (NHEJ) and base excision repai

158 lved several DSB repair mechanisms, of which nonhomologous end-joining (NHEJ) and homologous recombin

159 choice between two main DSB repair pathways, nonhomologous end-joining (NHEJ) and homologous recombin

160 esection in G1, and thereby favors repair by nonhomologous end-joining (NHEJ) as opposed to homologou

161 ing kinases and that it is not suppressed by nonhomologous end-joining (NHEJ) components, arguing tha

162 ugh conditional deletion of TRF1 and TRF2 in nonhomologous end-joining (NHEJ) deficient cells.

163 gase 4 (LIG4), NHEJ1, and NBS1 involving the nonhomologous end-joining (NHEJ) DNA repair pathway resu

164 53BP1 gene silencing induces defects in the nonhomologous end-joining (NHEJ) DNA repair pathway.

165 Hypomorphic mutations in the nonhomologous end-joining (NHEJ) DNA repair protein DNA

166 Such mutant alleles result presumably from nonhomologous end-joining (NHEJ) events before the segre

167 Ku70, a known nonhomologous end-joining (NHEJ) factor, also functions

168 Disruption of the nonhomologous end-joining (NHEJ) factor, Ku, promotes DN

169 t DNA ligation in vitro and assembly of core nonhomologous end-joining (NHEJ) factors on damaged chro

170 In the absence of core nonhomologous end-joining (NHEJ) factors, Ab gene class-

171 Somatic mutations in nonhomologous end-joining (NHEJ) genes (DCLRE1C/ARTEMIS,

172 Nonhomologous end-joining (NHEJ) is a key pathway for ef

173 Nonhomologous end-joining (NHEJ) is a major DNA double-s

174 Nonhomologous end-joining (NHEJ) is a major repair pathw

175 Nonhomologous end-joining (NHEJ) is the major DNA double

176 Furthermore, coexpression the nonhomologous end-joining (NHEJ) machinery from the clos

177 A double strand breaks (DSB) are repaired by nonhomologous end-joining (NHEJ) or homologous recombina

178 Subsequent repair of this break via the nonhomologous end-joining (NHEJ) or homology-directed re

179 triggering end resection and inhibiting the nonhomologous end-joining (NHEJ) pathway in G1 phase.

180 i, suggesting that HR is compromised and the nonhomologous end-joining (NHEJ) pathway is elicited to

181 The nonhomologous end-joining (NHEJ) pathway is essential fo

182 The nonhomologous end-joining (NHEJ) pathway is essential fo

183 The nonhomologous end-joining (NHEJ) pathway is the primary

184 y demonstrated that HSCs use the error-prone nonhomologous end-joining (NHEJ) pathway of DNA repair t

185 factor (XLF/Cernunnos) is a component of the nonhomologous end-joining (NHEJ) pathway of double-stran

186 aired DNA ends are joined by proteins of the nonhomologous end-joining (NHEJ) pathway of DSB repair t

187 d mutability, and abnormal regulation of the nonhomologous end-joining (NHEJ) pathway.

188 Nonhomologous end-joining (NHEJ) pathways repair DNA dou

189 ither by homologous recombination (HR) or by nonhomologous end-joining (NHEJ) pathways.

190 Cernunnos is involved in the nonhomologous end-joining (NHEJ) process during DNA doub

191 are suppressed by genetically eliminating Ku nonhomologous end-joining (NHEJ) protein, indicating tha

192 Here we show that FBXW7 facilitates nonhomologous end-joining (NHEJ) repair and that FBXW7 d

193 -protein kinase (DNA-PK) phosphorylation and nonhomologous end-joining (NHEJ) repair efficiency and f

194 of mice lacking Lig4, a ligase required for nonhomologous end-joining (NHEJ) repair of DNA double-st

195 lates at DNA double-strand breaks and favors nonhomologous end-joining (NHEJ) repair over ATM-depende

196 d impaired homologous recombination (HR) and nonhomologous end-joining (NHEJ) repair pathways, with d

197 Mycobacteria exploit nonhomologous end-joining (NHEJ) to repair DNA double-st

198 and exonuclease activities regulate DSBR by nonhomologous end-joining (NHEJ) versus homologous recom

199 revealed 47 to 58% of reads as repaired via nonhomologous end-joining (NHEJ) with deletions and/or s

200 However, nonhomologous end-joining (NHEJ), an error-prone repair,

201 DSBs, namely homologous recombination (HR), nonhomologous end-joining (NHEJ), and microhomology-medi

202 cle-invasive bladder tumors are defective in nonhomologous end-joining (NHEJ), and this phenotype may

203 tein TRF2 by promoting their mobility, their nonhomologous end-joining (NHEJ), and, as we show here,

204 ence of DNA damage checkpoint components and nonhomologous end-joining (NHEJ), but not homologous rec

205 ir by both homologous recombination (HR) and nonhomologous end-joining (NHEJ), causes accumulation of

206 ment in the second major DSB repair pathway, nonhomologous end-joining (NHEJ), remains controversial.

207 nstrict the DNA-binding ring of Ku80 disrupt nonhomologous end-joining (NHEJ), telomeric gene silenci

208 nderstood and has been proposed to occur via nonhomologous end-joining (NHEJ)-mediated double-strand

209 occur in human cancers display hallmarks of nonhomologous end-joining (NHEJ).

210 ase (DNA-PK), a critical enzyme required for nonhomologous end-joining (NHEJ).

211 ted an increased number of DSBs processed by nonhomologous end-joining (NHEJ).

212 NA double-strand break repair pathway termed nonhomologous end-joining (NHEJ).

213 eaks, to recapitulate DSB repair via MMEJ or nonhomologous end-joining (NHEJ).

214 RP-3 and APLF accelerate DNA ligation during nonhomologous end-joining (NHEJ).

215 NA repair, which is accompanied by increased nonhomologous end-joining activity.

216 d with wild-type cells, indicating that both nonhomologous end-joining and homologous recombination D

217 IgD CSR occurred via both alternative nonhomologous end-joining and homologous recombination p

218 ce between the two major DSB repair pathways-nonhomologous end-joining and homologous recombination r

219 se to DNA damage, which suppresses repair by nonhomologous end-joining and homologous recombination.

220 in the repair of DNA double strand breaks by nonhomologous end-joining and in the signaling of DNA da

221 fore, UbcH7-depleted cells display increased nonhomologous end-joining and reduced homologous recombi

222 y, which prevents end resection and promotes nonhomologous end-joining and therefore directly compete

223 While gene conversion and classical nonhomologous end-joining are the most physiologically p

224 PAXX was identified recently as a novel nonhomologous end-joining DNA repair factor in human cel

225 DNA-PKcs plays a critical role in the nonhomologous end-joining DNA repair pathway and provide

226 CHO cell lines, which are defective for the nonhomologous end-joining DNA repair pathway, revealed a

227 isruption applications by engaging mutagenic nonhomologous end-joining DNA repair pathways.

228 A damage sites and play a functional role in nonhomologous end-joining DNA repair.

229 and breaks in part through antagonism of the nonhomologous end-joining factor 53BP1.

230 SPR/SpCas9 system was used to knock out, via nonhomologous end-joining genome repair, the 4'OMT2 in o

231 melphalan sensitivity of the cells, with the nonhomologous end-joining inhibitor SCR7 showing the str

232 ologous recombination (HR) and the classical nonhomologous end-joining pathway (cNHEJ).

233 ir of DNA double-strand breaks (DSBs) by the nonhomologous end-joining pathway (NHEJ) is important no

234 d by the DCLRE1C gene, is a component of the nonhomologous end-joining pathway and participates in ha

235 ely because they mainly used the error-prone nonhomologous end-joining pathway to repair DSBs.

236 Ku70 is a key component of the nonhomologous end-joining pathway, which is the major pa

237 ich was necessary for DSB repair through the nonhomologous end-joining pathway.

238 DNA repair complexes that participate in the nonhomologous end-joining pathway.

239 pair, single strand break repair, and backup nonhomologous end-joining pathway.

240 ouble-stranded breaks (DSBs) mediated by the nonhomologous end-joining pathway.

241 ion-independent frameshifts generated by the nonhomologous end-joining pathway.

242 ubunit, essential DNA repair proteins in the nonhomologous end-joining pathway.

243 these double-strand breaks by the classical nonhomologous end-joining pathway.

244 NA double strand breaks that are repaired by nonhomologous end-joining pathways.

245 thways of homologous recombination and other nonhomologous end-joining processes.

246 re partially disassembled around DSBs during nonhomologous end-joining repair in G1-arrested mammalia

247 can be efficiently ligated by the classical nonhomologous end-joining repair pathway (c-NHEJ), regen

248 nts null for Ku70 or Lig4, components of the nonhomologous end-joining repair pathway.

249 ion and can ultimately become substrates for nonhomologous end-joining repair, leading to large-scale

250 HR)-mediated repair and, to a lesser extent, nonhomologous end-joining repair.

251 irectly to the DNA break and is required for nonhomologous end-joining repair.

252 s of chromothripsis in TCC-UB is mediated by nonhomologous end-joining using kilobase, rather than me

253 on and DNA-dependent protein kinase-mediated nonhomologous end-joining, and, when combined with olapa

254 ir through both homologous recombination and nonhomologous end-joining, implicating FUS as an upstrea

255 me of these rearrangements appear to involve nonhomologous end-joining, many must have involved mecha

256 h as KU70 and LIG4 (both involved in classic nonhomologous end-joining, NHEJ) and SMC6B (involved in

257 nt protein kinase-mediated (DNA-PK-mediated) nonhomologous end-joining, whereas DNA repair pathways m

258 nucleus" stage embryos led to high-frequency nonhomologous end-joining-mediated, mutagenic lesions in

259 defects that could be reversed by inhibiting nonhomologous end-joining.

260 ted double-strand-break creation followed by nonhomologous end-joining.

261 rtilization via homologous recombination and nonhomologous end-joining.

262 d that loss of MSI1 reduces the frequency of nonhomologous end-joining.

263 akpoint of proteins that promote error-prone nonhomologous end-joining.

264 Imprecise nonhomologous-end-joining (NHEJ) DNA repair following re

265 AD50/NBS1 complex and favors the error-prone nonhomologous-end-joining (NHEJ) DNA-repair pathway inst

266 Thus, convergent evolution of nonhomologous enzymes using the 2-His-1-carboxylate faci

267 via inverted repeats, and microhomologous or nonhomologous events.

268 In all regions, stimulation of nonhomologous fingers of the two hands elicited higher B

269 tion of residues in a homologous region from nonhomologous flanking residues).

270 coregulated, and (3) physical clustering of nonhomologous genes that encode components of secondary

271 zes the cytokine hbetaNGF was grafted into a nonhomologous human germ line V region.

272 ol, which is sufficient to protect mice from nonhomologous IAV challenge.

273 rovide substantial protection against lethal nonhomologous IAV challenge.

274 The three regions were each bordered by two nonhomologous integrase attachment (att) sites, which to

275 ailure and synapsis with both homologous and nonhomologous partners ("chromosome tangles").

276 hout necessitating degenerate recognition of nonhomologous peptides.

277 The arrays are nonhomologous, physically unlinked in mammals, and encod

278 ry modes by acquiring functionally divergent nonhomologous promoter regions.

279 he TM domains from sequences for a set of 23 nonhomologous proteins (resolution 1.8-3.0 A).

280 ucine zipper nomenclature) in homologous and nonhomologous proteins and influence interhelical angles

281 al sources with structural homology and also nonhomologous proteins arising from the same biological

282 olate binding was previously observed in the nonhomologous R67-encoded dihydrofolate reductase (dfrB

283 early phases of replication was a mixture of nonhomologous recombinants.

284 suggesting that the insert was the result of nonhomologous recombination with the host genome.

285 umerous rearrangements due to homologous and nonhomologous recombination, deletions and segmental dup

286 ntrol homologous recombination-dependent and nonhomologous recombination-dependent amplification path

287 eliminated in theory by avoiding ubiquitous nonhomologous recombination.

288 odels of CGR genesis and strongly argue that nonhomologous repair of concurrently arising DNA double-

289 ignments erroneously extend through flanking nonhomologous residues.

290 d specifically in non-PC regions, leading to nonhomologous SC assembly.

291 As R67 dihydrofolate reductase possesses a nonhomologous sequence and forms a tetrameric structure

292 ologies (homologous subsequences embedded in nonhomologous sequence).

293 structure and the structural prediction from nonhomologous sequences, despite the fact that the desig

294 The protocol is tested on 52 nonhomologous single-domain proteins, with an average se

295 reading frame 1 of the viral genome at five nonhomologous sites, releasing six nonstructural protein

296 f ECM from fully developed native tissues at nonhomologous sites.

297 ith unknown function, SRPKs contain a large, nonhomologous spacer insert domain (SID) that bifurcates

298 Similarly, we also observe that the more nonhomologous subunits that assemble together within a c

299 r, when the DSB end contains a 3' protruding nonhomologous tail, Msh2 promotes the rejection of misma

300 of new DNA synthesis, and the removal of the nonhomologous Y sequences.