ライフサイエンスコーパス: nonhomologous DNA end-joining

1 n and influences the efficiency of repair by nonhomologous DNA end joining.

2 nd then to undergo processing and joining by nonhomologous DNA end joining.

3 bility of the ligase complex is paramount in nonhomologous DNA end joining.

4 nts that facilitate successful completion of nonhomologous DNA end joining.

5 uberculosis ligDDelta cells are defective in nonhomologous DNA end joining.

6 and for the 5' and 3' overhang processing in nonhomologous DNA end joining.

7 making it relevant to the role of ARTEMIS in nonhomologous DNA end joining.

8 ast DNA ligase IV homologue is essential for nonhomologous DNA end joining [5-7], this has led to the

9 Moreover, Red1 exhibited nonhomologous DNA end-joining activity, thus revealing a

10 The classical nonhomologous DNA end-joining (C-NHEJ) double-strand bre

11 subunit (DNA-PKcs) and Artemis are classical nonhomologous DNA end-joining (C-NHEJ) factors required

12 Classical nonhomologous DNA end-joining (C-NHEJ), which is a major

13 Mammalian nonhomologous DNA end joining employs Ku70, Ku80, DNA-de

14 2-bp insertion that displayed hallmarks of a nonhomologous DNA end-joining event.

15 at mice deficient for the DNA Ligase4 (Lig4) nonhomologous DNA end-joining factor and the p53 tumor s

16 -PK inhibitor wortmannin or dependent on the nonhomologous DNA end-joining factor Xrcc4.

17 depends on the four evolutionarily conserved nonhomologous DNA end joining factors.

18 4 in regulating homologous recombination and nonhomologous DNA end joining-mediated DSB repair in hum

19 aks (DSBs) via efficient pathways of direct, nonhomologous DNA end joining (NHEJ) and homologous reco

20 eak repair pathways exist in all eukaryotes, nonhomologous DNA end joining (NHEJ) and homologous reco

21 Nonhomologous DNA end joining (NHEJ) and homologous reco

22 n kinase (DNA-PK) plays an essential role in nonhomologous DNA end joining (NHEJ) by initially recogn

23 ion is restricted to late S or G(2), whereas nonhomologous DNA end joining (NHEJ) can occur throughou

24 Nonhomologous DNA end joining (NHEJ) is the major pathwa

25 The nonhomologous DNA end joining (NHEJ) pathway is responsi

26 the ligase IV complex that is central to the nonhomologous DNA end joining (NHEJ) pathway, this raise

27 is:DNA-PKcs complex, and then joined via the nonhomologous DNA end joining (NHEJ) process.

28 double strand breaks in higher eukaryotes is nonhomologous DNA end joining (NHEJ), which modifies and

29 ring them: homologous recombination (HR) and nonhomologous DNA end joining (NHEJ).

30 cur either by homologous recombination or by nonhomologous DNA end joining (NHEJ).

31 epaired by homologous recombination (HR) and nonhomologous DNA end joining (NHEJ).

32 Nonhomologous DNA end-joining (NHEJ) is a major pathway

33 In humans, nonhomologous DNA end-joining (NHEJ) is the major pathwa

34 Nonhomologous DNA end-joining (NHEJ) is the predominant

35 The nonhomologous DNA end-joining (NHEJ) pathway contains si

36 The nonhomologous DNA end-joining (NHEJ) pathway is a key me

37 To assess the role of the DNA-PKcs nonhomologous DNA end-joining (NHEJ) protein in Ig heavy

38 ks (DSBs), homologous recombination (HR) and nonhomologous DNA end-joining (NHEJ).

39 ajor DNA double-strand break repair pathway (nonhomologous DNA end joining [NHEJ]) have increased spo

40 epair of all double-strand DNA breaks by the nonhomologous DNA end joining pathway in eukaryotes.

41 hat is distinct from the DNA-PK/Ku-dependent nonhomologous DNA end joining pathway.

42 l roles of three different components of the nonhomologous DNA end-joining pathway in the maintenance

43 ating that the rejoining phase relies on the nonhomologous DNA end-joining pathway.

44 We conclude that nonhomologous DNA end-joining plays a crucial role as a

45 Despite its central role in the nonhomologous DNA end joining process, we still have an

46 pendent protein kinase (DNA-PK)/Ku-dependent nonhomologous DNA end-joining proteins Xrcc4, DNA ligase

47 cDNA become joined together by the cellular nonhomologous DNA end-joining system to form two-long te

48 u subunit (pku70(+)) or ligase IV (lig4(+)), nonhomologous DNA end-joining was severely reduced.