ライフサイエンスコーパス: nonpermissive temperature

1 MHV-Brts31-infected cells is reduced at the nonpermissive temperature.

2 d/or replication in the infected cell at the nonpermissive temperature.

3 hese improperly processed transcripts at the nonpermissive temperature.

4 e improperly 3' processed transcripts at the nonpermissive temperature.

5 cytes carrying wild-type protein even at the nonpermissive temperature.

6 ription defects and inhibit apoptosis at the nonpermissive temperature.

7 3 at various sites on the cell cortex at the nonpermissive temperature.

8 f the nucleolus is abnormal in ycs4-1 at the nonpermissive temperature.

9 ; this strain was also unable to grow at the nonpermissive temperature.

10 ke intermediate genes, were expressed at the nonpermissive temperature.

11 enzyme is further reduced at 42 degrees C, a nonpermissive temperature.

12 ubiquitinate or to internalize Ste2p at the nonpermissive temperature.

13 early viral gene expression occurred at the nonpermissive temperature.

14 2 cells in a dominant-negative manner at the nonpermissive temperature.

15 es were detected in tsH5-4 infections at the nonpermissive temperature.

16 in the ubiquitin-activating enzyme E1, at a nonpermissive temperature.

17 o NGF was absent in PC12(p53ts) cells at the nonpermissive temperature.

18 cells or Deltacdc6 null mutant cells at the nonpermissive temperature.

19 r viral gene expression were detected at the nonpermissive temperature.

20 unable to import Ran into the nucleus at the nonpermissive temperature.

21 cell cycle block in ts13 cells grown at the nonpermissive temperature.

22 ptive budding site did not take place at the nonpermissive temperature.

23 dding and actin polarization occurred at the nonpermissive temperature.

24 ts showed reduced nuclear proteasomes at the nonpermissive temperature.

25 rature-sensitive pol III mutant (dnaE486) at nonpermissive temperature.

26 ochondrial inheritance and morphology at the nonpermissive temperature.

27 t defects have not been observed even at the nonpermissive temperature.

28 tin-activating enzyme (E1) upon shift to the nonpermissive temperature.

29 ented E. coli strain sensitive to GFZ at the nonpermissive temperature.

30 ture sensitive, forming small plaques at the nonpermissive temperature.

31 ambda gene rearrangement when shifted to the nonpermissive temperature.

32 ant cells appear to function normally at the nonpermissive temperature.

33 at least one round of DNA replication at the nonpermissive temperature.

34 so dramatically reduced in ts13 cells at the nonpermissive temperature.

35 2 viral DNA replication is unimpaired at the nonpermissive temperature.

36 with shorter poly(A) tails when grown at the nonpermissive temperature.

37 defect in NP protein)-infected cells at the nonpermissive temperature.

38 fected with a ts8 p35 deletion mutant at the nonpermissive temperature.

39 ls inhibited apoptosis of these cells at the nonpermissive temperature.

40 apidly undergo apoptosis when shifted to the nonpermissive temperature.

41 ive Ras GEF, Cdc25-2, allowing growth at the nonpermissive temperature.

42 in early but not late Golgi compartments at nonpermissive temperature.

43 rp43 was sufficient to restore growth at the nonpermissive temperature.

44 romuscular junctions of csp mutant larvae at nonpermissive temperature.

45 partial restoration of nsp5 activity at the nonpermissive temperature.

46 ired less frequently in cdc45-1 cells at the nonpermissive temperature.

47 ript abundance when cells are shifted to the nonpermissive temperature.

48 host cell but had an uncoating defect at the nonpermissive temperature.

49 PY and the secreted protein invertase at the nonpermissive temperature.

50 alize to a vacuolar membrane fraction at the nonpermissive temperature.

51 dentical to that of Alb/ts/nsp5/V148A at the nonpermissive temperature.

52 ature-sensitive mini-RK2 replicon grown at a nonpermissive temperature.

53 re selected based on colony formation at the nonpermissive temperature.

54 BHK tsBN7) induce CHOP when cultured at the nonpermissive temperature.

55 n binding to Spc110-220p is defective at the nonpermissive temperature.

56 markedly inhibited following incubation at a nonpermissive temperature.

57 ssed a differentiation phenotype only at the nonpermissive temperature.

58 titution of amino acid 186, binds p53 at the nonpermissive temperature.

59 ribosomal protein genes is repressed at the nonpermissive temperature.

60 ort of poly(A)+ RNA following a shift to the nonpermissive temperature.

61 ast-acting mei-1(ts) mutant was shifted to a nonpermissive temperature.

62 d fewer myxospores than the wild type at the nonpermissive temperature.

63 is mutant also fails to enter S phase at the nonpermissive temperature.

64 pro, blocking its function completely at the nonpermissive temperature.

65 5 with the U(L)28 and U(L)33 proteins at the nonpermissive temperature.

66 m10 in mcm10-1 mutants that are grown at the nonpermissive temperature.

67 nts after 24 h of incubation in LB medium at nonpermissive temperature.

68 ants, even after prolonged incubation at the nonpermissive temperature.

69 ally assumes that the protein is inactive at nonpermissive temperature.

70 mutant FabG proteins may be disrupted at the nonpermissive temperature.

71 in mutant, and the VSV-G ts045 mutant at the nonpermissive temperature.

72 rain JN394top2-4 expressing betaE522K at the nonpermissive temperature.

73 ured in vivo was inhibited upon shift to the nonpermissive temperature.

74 nsp5-mediated polyprotein processing at the nonpermissive temperature.

75 undergo rapid apoptosis after a shift to the nonpermissive temperature.

76 ject its virion DNA into the nucleus at this nonpermissive temperature.

77 islocalized to the vacuole in neo1-ts at the nonpermissive temperature.

78 he viral life cycle that was affected at the nonpermissive temperature.

79 n mutant cells before and after the shift to nonpermissive temperature.

80 erature-sensitive mutant when shifted to the nonpermissive temperature.

81 inhibit apoptosis in ts13 cells grown at the nonpermissive temperature.

82 se activities for wt NSP2 were higher at the nonpermissive temperature.

83 lly reduced in the doubly tagged strain at a nonpermissive temperature.

84 itro, but only the rice isoforms denature at nonpermissive temperatures.

85 E. coli strain that lacks BCCP when grown at nonpermissive temperatures.

86 scue the tsBN67 cell proliferation defect at nonpermissive temperatures.

87 d for enhanced survival during incubation at nonpermissive temperatures.

88 or no proteolytic activity at permissive and nonpermissive temperatures.

89 that rapidly blocks synaptic transmission at nonpermissive temperatures.

90 ions to trigger exocytosis in csp mutants at nonpermissive temperatures.

91 t of a temperature-sensitive sec31 mutant at nonpermissive temperatures.

92 e inactivated MGMT protein at permissive and nonpermissive temperatures.

93 ature-sensitive mutation in the UL15 gene at nonpermissive temperatures.

94 generate the TS phenotype at permissive and nonpermissive temperatures.

95 cally defective in Sir2-Sir4 interactions at nonpermissive temperatures.

96 emperature (30 degrees C) and shifted to the nonpermissive temperature (16 degrees C) form tumor-like

97 of precursor capsids in cells growing at the nonpermissive temperature (16 degrees C).

98 nd was severely impaired after growth at the nonpermissive temperature (18 degrees C).

99 e in virus yields between the permissive and nonpermissive temperatures (2.2 x 10(6) and 3 x 10(3), r

100 Although dhc1b-3 flagella at the nonpermissive temperature (34 degrees C) showed a dramat

101 hat sec14-3 cells could grow at an otherwise nonpermissive temperature (34 degrees C) when carrying a

102 clear gene (MNA6), which lose mt 15S rRNA at nonpermissive temperature (36 degrees C), were previousl

103 When shifted to the nonpermissive temperature (37 degrees C), TRF2ts cells s

104 The transfer of endothelial cells to nonpermissive temperatures (37 degrees C) resulted in ce

105 ucrose, and betaine also reactivate PmMDH at nonpermissive temperatures (37 degrees C).

106 At the nonpermissive temperatures (37-39 degrees C), they stop

107 After transfer to the "nonpermissive" temperature (37 degrees C), they entered

108 eplication immediately after transfer to the nonpermissive temperature [37 degrees C]) and three (1-2

109 s mutant ceased after one cell doubling at a nonpermissive temperature, 37 degrees C.

110 f the second splicing reaction, while at the nonpermissive temperature (39 degrees C), both splicing

111 tential at 33 degrees C, but on shift to the nonpermissive temperature (39 degrees C), they show dimi

112 activating enzyme E1, were incubated at the nonpermissive temperature (39.5 degrees C) in the presen

113 At the nonpermissive temperature (39.5 degrees C), transcriptio

114 cells, stably expressing human iNOS, at the nonpermissive temperature (40 degrees C) resulted in inh

115 s aligned by a shift of dnaC2(Ts) mutants to nonpermissive temperature (40 degrees C), mioC transcrip

116 ensitive VSV mutant (ts045) and grown at the nonpermissive temperature (40.5 degrees C), cells transi

117 e a defect in chromosome partitioning at the nonpermissive temperature 42 degrees.

118 30 degrees C and was further reduced at the nonpermissive temperature (42 degrees C).

119 y synthesized lipid A was not cleaved at the nonpermissive temperature (44 degrees C).

120 emperature (30 degrees C) versus that at the nonpermissive temperature (45 degrees C); (ii) transposi

121 120/R273K mutant suppressed apoptosis at the nonpermissive temperature, a phenotype correlated with i

122 When grown at the nonpermissive temperature, Ad5 ts147 replicates normally

123 Dts38], Dts12, and Dts56) and shown that at nonpermissive temperature all of the tsD5 viruses exhibi

124 Incubation at the nonpermissive temperature also precluded coimmunoprecipi

125 fect in the accumulation of viral DNA at the nonpermissive temperature, although both the A20 protein

126 Upon shifting the vam3(tsf) mutant cells to nonpermissive temperature, an immediate block in protein

127 Ad2ts1 was prepared at a nonpermissive temperature and contains the precursor for

128 mutations was inhibited upon a shift to the nonpermissive temperature and in the latter case decline

129 ed in as little as 30 s after a shift to the nonpermissive temperature and is accompanied by a dramat

130 cells in a G(0)-like state when grown at the nonpermissive temperature, and the same domain interacts

131 hat capsids present within cells infected at nonpermissive temperatures are also cryosensitive and di

132 Synchronized mutant cells incubated at the nonpermissive temperature arrest as large budded cells w

133 0 cells is nearly completely reverted at the nonpermissive temperature as well.

134 causing a delayed entry into S phase at the nonpermissive temperature, as well as a high plasmid los

135 At the nonpermissive temperature at which viral DNA synthesis w

136 Aspergillus, their growth is arrested at the nonpermissive temperature, because the scNek2/Kin3 (D55G

137 a temperature-sensitive VSV-M mutant at the nonpermissive temperature both substantially reversed th

138 have the wild-type sequence; however, at the nonpermissive temperature, both E1 and PE2 are retained

139 Upon a shift to a nonpermissive temperature, both large and small-ribosoma

140 In a ydj1 mutant at the nonpermissive temperature, both phosphorylation and degr

141 At nonpermissive temperature, bub3 clb5-ts cells showed def

142 M failed to accumulate in the nucleus at the nonpermissive temperature but did accumulate when the pe

143 e temperature and after several hours at the nonpermissive temperature but display aberrant organizat

144 rly proteins were detected at permissive and nonpermissive temperatures, but one mutant showed an abs

145 Apoptosis also was suppressed at the nonpermissive temperature by constitutively active Akt a

146 Examination of vam7(tsf) cells at the nonpermissive temperature by electron microscopy reveale

147 e protected from cell death on incubation at nonpermissive temperature by mutation in the cydA gene c

148 201 is reversible, and capsids formed at the nonpermissive temperature can undergo maturational cleav

149 synthesis, and thus lack of function at the nonpermissive temperature cannot be attributed to a lack

150 However, exposure to Mg(2+) and the nonpermissive temperature caused disruption of the tsE o

151 on of cells with thermosensitive Sec17-1p at nonpermissive temperature causes SNARE complex disassemb

152 At the nonpermissive temperature, cdc20 cells arrested with a s

153 We show that at the nonpermissive temperature, cdc68-1 mutants arrest as unb

154 At the nonpermissive temperature, cells expressing a 338-amino

155 ouble-mutant phenotype indicated that at the nonpermissive temperature, cells failed to undergo cytok

156 At the nonpermissive temperature, cessation of large T antigen

157 ar-targeted proteins in the cytoplasm at the nonpermissive temperature consistent with a defect in nu

158 ccumulate poly(A)+ RNA in the nucleus at the nonpermissive temperature, consistent with a failure to

159 Cells infected with tsE and maintained at nonpermissive temperature contain few replication-assemb

160 plasm of cells that had been infected at the nonpermissive temperature contained large granular areas

161 prepared from these cells, when grown at the nonpermissive temperature, contained about 5% SecY and s

162 strong mouse-specific defect of PV1(RIPO) at nonpermissive temperature correlated with the translatio

163 the dam1-1 allele becomes delocalized at the nonpermissive temperature, correlating with the subseque

164 At the nonpermissive temperature, cultures of the mutant strain

165 In contrast, the nonpermissive temperature did not affect class I present

166 Surprisingly, incubation at the nonpermissive temperature did not inhibit class I presen

167 vam7(tsf) mutant cells incubated at the nonpermissive temperature displayed rapid defects in the

168 Virions produced at the nonpermissive temperature do not assemble capsids, altho

169 cdc5-1 mutants arrest at telophase at the nonpermissive temperature due to the failure of CDK inac

170 that in ts23-infected cells incubated at the nonpermissive temperature, E1 folding is disrupted early

171 At the nonpermissive temperature, estrogen specifically induced

172 e mutant proteins were largely stable at the nonpermissive temperature except the A68T/N73D mutant pr

173 or olsA gene products supported growth at a nonpermissive temperature, exhibited AGPAT activity in v

174 sion of ORF P; (ii) in cells infected at the nonpermissive temperature for ICP4, ORF O protein is mad

175 whereas it was inhibited at 32 degrees C, a nonpermissive temperature for KHP1(FLA10).

176 ibroblast growth factor at 39 degrees C, the nonpermissive temperature for T function, resulted in th

177 fold more in a lon ftsH double mutant at the nonpermissive temperature for the ftsH mutation.

178 Coinfection of these two DIs at the nonpermissive temperature for the ts helper virus result

179 cantly reduced if assayed at 30 degrees C, a nonpermissive temperature for Ty1 retrotransposition, or

180 At the nonpermissive temperature, four out of five RPA2 mutants

181 lication immediately halts upon a shift to a nonpermissive temperature, growth and DNA replication of

182 archaeal and bacterial cysS genes grew at a nonpermissive temperature, growth was also supported by

183 uses (2B33F and 2B20L) at the permissive and nonpermissive temperatures have been compared with that

184 Instead of a cell division defect at the nonpermissive temperature, however, revertants displayed

185 factor) were completely blocked in the ER at nonpermissive temperature; however, other proteins (i.e.

186 sis of independently isolated mutants at the nonpermissive temperature identified a variety of well-d

187 This transcript is also absent at nonpermissive temperature in a 10-1 mouse cell line lack

188 At the nonpermissive temperature in a LepBts (leader peptidase

189 ystem in Escherichia coli, was depleted at a nonpermissive temperature in a strain which had a temper

190 regulator of chromosome condensation) at the nonpermissive temperature in the thermosensitive mutant

191 nt in releasing mRNA from the spliceosome at nonpermissive temperature in vitro, the suppressor prote

192 e tested was impaired at both permissive and nonpermissive temperatures in secY40 cells grown in eith

193 coat protein mutants which can be rescued at nonpermissive temperatures in vivo by the overproduction

194 hibited upon shift of mutant cultures to the nonpermissive temperature, indicating blockage of the sy

195 n ts v-G37E-transformed cells shifted to the nonpermissive temperature, indicating that an ICE-like p

196 nt mutation are strongly bactericidal at the nonpermissive temperature, indicating that this pathway

197 (iv) Mutant HSV-1(HFEM)tsB7 at the nonpermissive temperature infects cells but the DNA is n

198 risingly, certain ftsZ84 strains lyse at the nonpermissive temperature instead of filamenting, and in

199 ous ts alleles of spe-9, loss of function at nonpermissive temperatures is not due to protein misloca

200 ediate-early transcripts and proteins at the nonpermissive temperature, it did not produce any early

201 1% at the permissive temperature, and at the nonpermissive temperature, it renders further deteriorat

202 ion of this conditional-lethal mutant at the nonpermissive temperature led to aggregated mitochondria

203 train carrying an ftsZ84(Ts) mutation to the nonpermissive temperature led to loss of Z rings within

204 inhibition of leaf development in lem7 under nonpermissive temperatures may serve as a useful tool fo

205 At the nonpermissive temperature, MEK and ERKs were activated t

206 in virus-infected cells showed that, at the nonpermissive temperature, MHV-Brtsc31 was not able to p

207 At the nonpermissive temperature, neither virus forms macroscop

208 of temperature-conditional vps9 cells to the nonpermissive temperature, newly synthesized carboxypept

209 At the nonpermissive temperature, newly synthesized fusion prot

210 At the nonpermissive temperature (NPT), tsB7 capsids accumulate

211 erature-sensitive (ts) mutant viruses at the nonpermissive temperature (NPT).

212 roduced immediate-early (IE) proteins at the nonpermissive temperature (NPT).

213 At the nonpermissive temperature of 33 degrees C, this mutant f

214 Selection in growth medium at the nonpermissive temperature of 35 degrees in the presence

215 rphology seen in rat7-1 cells shifted to the nonpermissive temperature of 37 degrees C and, thus, res

216 ermissive temperature of 23 degrees C to the nonpermissive temperature of 37 degrees C on the process

217 olera toxin (CT) promoter-lacZ fusion at the nonpermissive temperature of 37 degrees C.

218 sProt.A accumulate unpackaged capsids at the nonpermissive temperature of 39 degrees C.

219 At the nonpermissive temperature of 39 degreesC, scid pre-B cel

220 At the nonpermissive temperature of 39.5 degrees C, the Chinese

221 infection is initiated and maintained at the nonpermissive temperature of 39.5 degrees C.

222 ponent of TFIID complex, arrest in G1 at the nonpermissive temperature of 39.5 degrees C.

223 After a shift to the nonpermissive temperature of 40.5 degrees C, the rates o

224 that the cells rapidly lose viability at the nonpermissive temperature of 42 degrees C as well as sho

225 affect the mutant protein's stability at the nonpermissive temperature or its ability to associate wi

226 At nonpermissive temperatures, p53val135 remains sequestere

227 their only carbon source, and accumulate at nonpermissive temperatures predominantly as large-budded

228 7 hamster cell line arrests proliferation at nonpermissive temperatures, primarily in a G(0)/G(1) sta

229 ibits a loss of silencing when raised to the nonpermissive temperature regardless of cell-cycle posit

230 entous phenotype following incubation at the nonpermissive temperature, reminiscent of a defect in ce

231 tions in proteins produced at or heated to a nonpermissive temperature render the proteins defective

232 Passage of tsS133A and tsF219L at the nonpermissive temperature resulted in emergence of multi

233 Infection of mycobacteria at the nonpermissive temperature results in highly efficient tr

234 The mutant's defect at the nonpermissive temperature results, at least in part, fro

235 RNA obtained from the ts strain shifted to a nonpermissive temperature revealed accumulation of unspl

236 xamination of ts1249 capsids produced at the nonpermissive temperature revealed that, in comparison w

237 wth at 37 degrees C, and upon a shift to the nonpermissive temperature show an accumulation of large

238 At the nonpermissive temperature, significant mitotic delay, ch

239 sI temperature-sensitive mutant grown at the nonpermissive temperature, some filaments displaying a s

240 in translation of the tap42-11 mutant at the nonpermissive temperature, suggest that Tap42, Sit4, and

241 st in mitosis with monopolar spindles at the nonpermissive temperature, suggesting a defect in SPB du

242 d processes at the permissive as well as the nonpermissive temperature, suggesting that cells express

243 n strains carrying ftsW(Ts) mutations at the nonpermissive temperature, suggesting that FtsW is unlik

244 efore tsBN67 cells stop proliferating at the nonpermissive temperature, suggesting that loss of HCF-1

245 m wild-type virus in assays performed at the nonpermissive temperature, suggesting that the ts mutati

246 ion that was transcriptionally silent at the nonpermissive temperature, suggesting that thermoregulat

247 isiae dna2-1 mutant strain for growth at the nonpermissive temperature, suggesting that XDna2p is a f

248 the lethal phenotype of smc1-2 and smc2-6 at nonpermissive temperatures, suggesting that the interact

249 layed a modestly increased Cse4 half-life at nonpermissive temperatures, suggesting that turnover of

250 of temperature-sensitive E. coli Y815 at the nonpermissive temperature, supporting its biological act

251 s of tsE NSP2 were significantly less at the nonpermissive temperature than at the permissive tempera

252 rat8-2p localized to cytoplasmic granules at nonpermissive temperature that are distinct from P-bodie

253 We demonstrated that at the nonpermissive temperature the DnaB(A116V) mutant arreste

254 At nonpermissive temperature the G protein failed to fold c

255 At the nonpermissive temperature, the capsids accumulate at the

256 In an ipl1-2 yeast strain, shifted to the nonpermissive temperature, the chromosomes and plasmid a

257 When shifted to the new lower nonpermissive temperature, the double mutant formed long

258 when unfolded by a shift from permissive to nonpermissive temperature, the G protein was reglucosyla

259 nt 143ala revealed that at 32 degrees C, the nonpermissive temperature, the growth of breast epitheli

260 At the nonpermissive temperature, the temperature-sensitive phe

261 At the nonpermissive temperature these mutations have drastic e

262 At nonpermissive temperatures, they fail to splice, resulti

263 At the nonpermissive temperature, this virus, designated ts8-22

264 cdc13-1 yeast grown at the nonpermissive temperature undergo G2/M arrest, progressi

265 shown that these cells enter mitosis at the nonpermissive temperature upon incubation with okadaic a

266 formed growth-based selection experiments at nonpermissive temperatures using a library of random bet

267 At the nonpermissive temperature, vA6L-mut2 was normal at viral

268 At the nonpermissive temperature, viral gene expression and DNA

269 cause thermolability of the protein; at the nonpermissive temperature, virion morphogenesis arrests

270 cells transfected with the ts mutant at the nonpermissive temperature was comparable to that of wild

271 1 injected into nuclei of tsBN2 cells at the nonpermissive temperature was exported.

272 lude viral DNA cleavage and packaging at the nonpermissive temperature was identified as a change fro

273 ntegrase in mutant particles produced at the nonpermissive temperature was inconsistent with defectiv

274 Overexpression of topoisomerase III at the nonpermissive temperature was shown subsequently to rest

275 removal of the inhibitors and a shift to the nonpermissive temperature, we assayed for protein transp

276 At the nonpermissive temperature, we find that RPA1 and RPA2 ar

277 cted for defective ribosome synthesis at the nonpermissive temperature were also found to have defect

278 rs accumulated in sec31-sec35 mutants at the nonpermissive temperature were core-glycosylated but lac

279 nfectivity of mutant virions produced at the nonpermissive temperature were greatly reduced when assa

280 ol) were detected in virions produced at the nonpermissive temperature when the HIV-1 protease was in

281 istribute back to the ER upon a shift to the nonpermissive temperature, where they misfolded and were

282 pendent leader peptidase is inhibited at the nonpermissive temperature, whereas the insertion of the

283 her (i) a temperature-sensitive virus at its nonpermissive temperature which does not inject viral DN

284 had decreased levels of 60S subunits at the nonpermissive temperature which resulted in the formatio

285 ressors of dnaN5 that restored growth at the nonpermissive temperature while maintaining an increase

286 e prevented by the infection of cells at the nonpermissive temperature with a mutant virus defective

287 mosome maintenance defect and arrests at the nonpermissive temperature with dumbbell morphology and 2

288 All five mutant T antigens bind pRb at the nonpermissive temperature with efficiencies similar to t

289 In cells infected at a nonpermissive temperature with mu2-mutant virus tsH11.2,

290 In cells infected at a nonpermissive temperature with sigmaNS-mutant virus tsE3

291 ial nucleoid structure also collapsed at the nonpermissive temperature with similar kinetics.

292 ere also isolated from cells infected at the nonpermissive temperature with the HSV-1 mutant tsProt.A

293 e yip1-4 allele accumulate ER membranes at a nonpermissive temperature, with no apparent accumulation

294 rently normal distribution at permissive and nonpermissive temperatures, yet mitosis appears to be ab