ライフサイエンスコーパス: nonreceptor tyrosine kinase

1 ndependent of the Smad proteins is the c-Abl nonreceptor tyrosine kinase.

2 ing the interaction of a P-type ATPase and a nonreceptor tyrosine kinase.

3 or through phosphorylation of Abl by the Src nonreceptor tyrosine kinase.

4 al consequence of expression of an activated nonreceptor tyrosine kinase.

5 v-Abl is an oncogenic form of the c-Abl nonreceptor tyrosine kinase.

6 ells, demonstrating its ability to inhibit a nonreceptor tyrosine kinase.

7 The v-src oncogene encodes a nonreceptor tyrosine kinase.

8 n kinase C, or herbimycin A, an inhibitor of nonreceptor tyrosine kinase.

9 f activated Cdc42-associated kinase (Ack), a nonreceptor tyrosine kinase.

10 ABL2, also known as ARG, a membrane-anchored nonreceptor tyrosine kinase.

11 strate of the Abl and Abl-related gene (Arg) nonreceptor tyrosine kinases.

12 ional molecule such as CD44, which activates nonreceptor tyrosine kinases.

13 ation by p210bcr/abl as well as receptor and nonreceptor tyrosine kinases.

14 rosine kinases or proteasomal degradation of nonreceptor tyrosine kinases.

15 rged as a negative regulator of receptor and nonreceptor tyrosine kinases.

16 ers of this family associate with Jak family nonreceptor tyrosine kinases.

17 h factor, nerve growth factor receptors, and nonreceptor tyrosine kinases.

18 f neuronal potassium current by receptor and nonreceptor tyrosine kinases.

19 o-related GTP-binding proteins, PKC-zeta and nonreceptor tyrosine kinases.

20 d, which encodes a phosphoprotein that binds nonreceptor tyrosine kinases.

21 sponse to activation of various receptor and nonreceptor tyrosine kinases.

22 own as Etk, is a member of the Tec family of nonreceptor tyrosine kinases.

23 Activation of the nonreceptor tyrosine kinase Abelson (Abl) contributes to

24 Using MEDUSA, we find that the conserved nonreceptor tyrosine kinase Abelson (Abl) contributes to

25 nt proteomic analysis has predicted that the nonreceptor tyrosine kinase Abelson murine leukemia vira

26 Nonreceptor tyrosine kinase Abl is an actin-binding prot

27 ABL1 gene encodes the ubiquitously expressed nonreceptor tyrosine kinase ABL.

28 yrosine 88 of p27 for phosphorylation by the nonreceptor tyrosine kinase Abl.

29 onsensus sequence for phosphorylation by the nonreceptor tyrosine kinases Abl and Arg.

30 C-abl oncogene 1, nonreceptor tyrosine kinase (ABL1) kinase inhibitors suc

31 Here, we report that the cdc42-activated, nonreceptor tyrosine kinase, Ack1, is a DAT endocytic br

32 Many receptor and nonreceptor tyrosine kinases activate phosphoinositide 3

33 signaling pathways required for receptor and nonreceptor tyrosine kinase activation by H2O2 involving

34 sis.SIGNIFICANCE STATEMENT The Src family of nonreceptor tyrosine kinases acts in signaling pathways

35 Expression of the receptor and nonreceptor tyrosine kinases, alpha platelet-derived gro

36 pp60(c-src) is a prototypical nonreceptor tyrosine kinase and may play a role in disea

37 and Fc gamma RIIIb required activation of a nonreceptor tyrosine kinase and phosphatidylinositol 3-k

38 The c-Abl nonreceptor tyrosine kinase and the c-Jun NH2-terminal k

39 1 (activated Cdc42-associated kinase 1) is a nonreceptor tyrosine kinase and the only tyrosine kinase

40 lization, down-regulation, and signaling via nonreceptor tyrosine kinases and mitogen-activated prote

41 ne kinase (BTK) belongs to the TEC family of nonreceptor tyrosine kinases and plays a critical role i

42 -containing proteins, including receptor and nonreceptor tyrosine kinases and their phosphorylated su

43 onal responses to cytokines, growth factors, nonreceptor tyrosine kinases, and a variety of oncogenic

44 Both Arp2/3 complex and the Abl2/Arg nonreceptor tyrosine kinase are essential to form and ma

45 Src family nonreceptor tyrosine kinases are an integral component o

46 Jak (Janus kinase) family nonreceptor tyrosine kinases are central mediators of cy

47 The Src family of nonreceptor tyrosine kinases are important regulators of

48 The activities of the related Abl and Arg nonreceptor tyrosine kinases are kept under tight contro

49 Tec family nonreceptor tyrosine kinases are key immunological enzym

50 sponse to ligand-receptor interaction, these nonreceptor tyrosine kinases are rapidly phosphorylated

51 the Abelson (Abl) and Abl-related gene (Arg) nonreceptor tyrosine kinases are required for maintenanc

52 dy, we provide evidence that the Abl-related nonreceptor tyrosine kinase Arg mediates epidermal growt

53 Extracellular cues stimulate the Abl family nonreceptor tyrosine kinase Arg to promote actin-based c

54 The Abl family nonreceptor tyrosine kinase Arg/Abl2 interacts with cort

55 point cluster region - ABL proto-oncogene 1, nonreceptor tyrosine kinase (BCR-ABL1) antagonist inhibi

56 factor receptors EGFR, VEGFR, and FGFR) and nonreceptor tyrosine kinases (Bcr-Abl), where advances h

57 Cbl and the Abl nonreceptor tyrosine kinase both bind to SH3 domains fro

58 ch then sequentially bound and activated the nonreceptor tyrosine kinases Bruton's tyrosine kinase (B

59 Mutations in the nonreceptor tyrosine kinase Btk result in the B cell imm

60 ctivation of G(alphaq) and both receptor and nonreceptor tyrosine kinases but that is independent of

61 a in bone marrow, expression of receptor and nonreceptor tyrosine kinases by androgen-independent PCa

62 transduces promitogenic signals from various nonreceptor tyrosine kinases by orchestrating its own ph

63 Expression of the nonreceptor tyrosine kinase c-Abl and Smad1 was blocked

64 (IR) treatment results in activation of the nonreceptor tyrosine kinase c-Abl because of phosphoryla

65 Oligomerization of the nonreceptor tyrosine kinase c-Abl can activate its trans

66 The ubiquitously expressed nonreceptor tyrosine kinase c-Abl contains three nuclear

67 Here, we report that hyperactivity of the nonreceptor tyrosine kinase c-Abl critically regulates a

68 The requirement for the nonreceptor tyrosine kinase c-abl in the pathogenesis of

69 The nonreceptor tyrosine kinase c-Abl is tightly regulated i

70 Here we show that the nonreceptor tyrosine kinase c-Abl phosphorylates tyrosin

71 The ubiquitously expressed nonreceptor tyrosine kinase c-Abl regulates stress respo

72 en NRP-1, the scaffold protein GIPC, and the nonreceptor tyrosine kinase c-Abl that augmented alpha5b

73 We show that the nonreceptor tyrosine kinase c-SRC (SRC) is a key modulat

74 tigen (PyMT) oncogene activates the cellular nonreceptor tyrosine kinase c-Src and recruits the Hippo

75 n kinase Calpha (PKCalpha) activation of the nonreceptor tyrosine kinase c-Src and the subsequent for

76 The localization of the nonreceptor tyrosine kinase c-Src appeared disrupted in

77 The function of the nonreceptor tyrosine kinase c-Src as a plasma membrane-a

78 have investigated the role of the ubiquitous nonreceptor tyrosine kinase c-Src in activation of the M

79 dermal growth factor receptor (EGFR) and the nonreceptor tyrosine kinase c-Src may contribute to an a

80 The catalytic activity of the nonreceptor tyrosine kinase c-Src, but not the epidermal

81 tablished a complex consisting of MerTK, the nonreceptor tyrosine kinase c-Src, the transcription fac

82 trates its utility in activity assays of the nonreceptor tyrosine kinase c-Src.

83 e demonstrated that bradykinin activates the nonreceptor tyrosine kinase c-src.

84 study that occludin was colocalized with the nonreceptor tyrosine kinase c-Yes at cell junction areas

85 In addition, we show that the nonreceptor tyrosine kinase c-Yes is contained within EB

86 formation in epithelial cells, and that the nonreceptor tyrosine kinase c-Yes is involved in the reg

87 ical EBP50 protein complexes, containing the nonreceptor tyrosine kinase c-Yes, may regulate apical s

88 proteins have been identified, including the nonreceptor tyrosine kinases c-Abl and Arg, and the guan

89 ed kinase-2 (PAK2) and activation of abelson nonreceptor tyrosine kinase (c-abl) have been shown rece

90 cle and is modulated by endogenous levels of nonreceptor tyrosine kinase, c-src.

91 ma subunit-mediated activation of Src family nonreceptor tyrosine kinases can account for the Gi-coup

92 The 32 nonreceptor tyrosine kinases can be placed in 10 subfami

93 ta pathways results in the activation of the nonreceptor tyrosine kinase cellular Abelson (c-Abl), an

94 dies have demonstrated a requirement for the nonreceptor tyrosine kinase, cellular Src (c-Src), in ep

95 The Abl family nonreceptor tyrosine kinases, consisting of closely rela

96 The Abl family of mammalian nonreceptor tyrosine kinases consists of c-Abl and ARG (

97 The Abl family of nonreceptor tyrosine kinases consists of two related pro

98 ation of a single C-terminal tyrosine by the nonreceptor tyrosine kinase Csk.

99 Here we report that the nonreceptor-tyrosine-kinase Csk is an essential componen

100 Here we identify CaMKII and the nonreceptor tyrosine kinase DFak as critical intermediat

101 The nonreceptor tyrosine kinase encoded by the c-Abl gene ha

102 The nonreceptor tyrosine kinase, encoded by the v-Abl oncoge

103 wth by modulating the expression of PEAK1, a nonreceptor tyrosine kinase essential for PDAC cell grow

104 Janus kinase 3 (Jak3) is a nonreceptor tyrosine kinase essential for signaling via

105 Janus kinase 3 (Jak3) is a nonreceptor tyrosine kinase expressed in both hematopoie

106 Janus kinase 3 (Jak3) is a nonreceptor tyrosine kinase expressed in both hematopoie

107 The nonreceptor tyrosine kinase FAK ("focal adhesion kinase"

108 on-independent activation of MET through the nonreceptor tyrosine kinase feline sarcoma-related (FER)

109 cells with JMP results in the release of the nonreceptor tyrosine kinase Fer from the cadherin comple

110 Previous characterization of the nonreceptor tyrosine kinase FER identified a tight physi

111 The c-fes protooncogene encodes a nonreceptor tyrosine kinase (Fes) implicated in cytokine

112 The c-fes protooncogene encodes a nonreceptor tyrosine kinase (Fes) implicated in cytokine

113 The nonreceptor tyrosine kinase focal adhesion kinase (FAK)

114 The activity of the nonreceptor tyrosine kinase, focal adhesion kinase (FAK)

115 We found that three nonreceptor tyrosine kinases, focal adhesion kinase (FAK

116 ar focal adhesions is the interaction of two nonreceptor tyrosine kinases, focal adhesion kinase (FAK

117 The product of the c-abl protooncogene is a nonreceptor tyrosine kinase found in both the cytoplasm

118 e Caenorhabditis elegans ortholog of the Fer nonreceptor tyrosine kinase, FRK-1, limits Wnt signaling

119 , we found that activation of the Src family nonreceptor tyrosine kinase Fyn in oligodendrocytes lead

120 ng pathway elucidated to date, converging on nonreceptor tyrosine kinase Fyn.

121 Bmx nonreceptor tyrosine kinase has an established role in e

122 The SH3-SH2-kinase domain arrangement in nonreceptor tyrosine kinases has been conserved througho

123 The Src family of nonreceptor tyrosine kinases has been implicated in many

124 ow kinase in chromosome X (Bmx), an arterial nonreceptor tyrosine kinase, has been shown to inhibit c

125 Etk/Bmx, a member of the Tec family of nonreceptor tyrosine kinases, has been implicated in the

126 The SH3 domains of src and other nonreceptor tyrosine kinases have been shown to associat

127 Inhibitors of the JAK family of nonreceptor tyrosine kinases have demonstrated clinical

128 duction by transforming variants of c-Fes, a nonreceptor tyrosine kinase implicated in cytokine signa

129 c-Src is an extensively studied nonreceptor tyrosine kinase implicated in mammary tumori

130 Furthermore, focal adhesion kinase (FAK), a nonreceptor tyrosine kinase important for regulating cel

131 t little is known about the function of this nonreceptor tyrosine kinase in chronic lymphocytic leuke

132 We have studied the role of Src family nonreceptor tyrosine kinases in G protein-coupled recept

133 s most likely the scm gene, thus implicating nonreceptor tyrosine kinases in neuronal migration and l

134 We have examined the role of the nonreceptor tyrosine kinases in the signaling mechanism(

135 iating cytokine signaling, the role of other nonreceptor tyrosine kinases in this process remains unc

136 s a role for Arg, a member of the Abl family nonreceptor tyrosine kinases, in the regulation of adhes

137 n to increase the kinase activity of several nonreceptor tyrosine kinases including Jak2 and c-Src.

138 Caveolin-1 is a substrate for nonreceptor tyrosine kinases including Src, Fyn, and Abl

139 urn, may through integrin signaling activate nonreceptor tyrosine kinases, including p72Syk, and late

140 The Tec family nonreceptor tyrosine kinase inducible T cell kinase (ITK

141 Pretreatment of OK cells with the nonreceptor tyrosine kinase inhibitors genistein and her

142 c-Abl, a conserved nonreceptor tyrosine kinase, integrates genotoxic stress

143 hose activity is stimulated by I-R. c-Abl, a nonreceptor tyrosine kinase, interacts with ATM and is a

144 Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase involved in development and

145 The c-abl proto-oncogene encodes a nonreceptor tyrosine kinase involved in many cellular pr

146 he c-Abl protein is a ubiquitously expressed nonreceptor tyrosine kinase involved in the development

147 The c-Abl nonreceptor tyrosine kinase is activated by growth facto

148 The Abl nonreceptor tyrosine kinase is activated by ligand-stimu

149 demonstrate that the Abl-related gene (Arg) nonreceptor tyrosine kinase is required for dynamic lame

150 Signaling by a variety of receptor and nonreceptor tyrosine kinases is mediated by Ras, a membr

151 functions of the Src homology 2 sequences of nonreceptor tyrosine kinases is to provide a binding sit

152 Bruton's tyrosine kinase (BTK), a nonreceptor tyrosine kinase, is a member of the Tec fami

153 Here we show that Src, a nonreceptor tyrosine kinase, is overexpressed in androge

154 e that c-Fes, unlike c-Src, c-Abl, and other nonreceptor tyrosine kinases, is constitutively oligomer

155 The nonreceptor tyrosine kinases Jak1 and Jak3, which bind t

156 recurrent somatic activating mutation in the nonreceptor tyrosine kinase JAK2 (JAK2V617F) occurs in t

157 nvolve members of the Janus kinase family of nonreceptor tyrosine kinases JAK2, TYK2, and signal tran

158 5, a somatic activating mutation in the JAK2 nonreceptor tyrosine kinase (JAK2V617F) was identified i

159 dy is that contrary to previous reports, the nonreceptor tyrosine kinase, Jak3 (Janus kinase 3), does

160 s are thought to involve the Janus family of nonreceptor tyrosine kinases (JAKs) and the signal trans

161 M140, the focal adhesion kinase p125(fak), a nonreceptor tyrosine kinase known to mediate integrin-de

162 Cbl associates with the lymphoid-restricted nonreceptor tyrosine kinase Lck, but the functional rele

163 hsp90-dependent protein, the T cell-specific nonreceptor tyrosine kinase lck.

164 Here, we present the first evidence that the nonreceptor tyrosine kinase, Matk/CHK, is an important m

165 phatidylinositol (GPI)-anchored proteins and nonreceptor tyrosine kinases may preferentially partitio

166 hibition of inducible T-cell kinase (ITK), a nonreceptor tyrosine kinase, may represent a novel treat

167 We have cloned, expressed, and purified the nonreceptor tyrosine kinase MbSrc1 from the choanoflagel

168 These studies identify a regulated nonreceptor tyrosine kinase-mediated pathway for targeti

169 Here, we report that the c-Abl nonreceptor tyrosine kinase negatively regulates the rep

170 binding to LFA-1 results in activation of a nonreceptor tyrosine kinase (NRTK) signaling cascade.

171 Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase (NRTK) with key roles in int

172 -1 by other Src homology 2 domain-containing nonreceptor tyrosine kinases (NRTKs).

173 human leukemias, whose protein product is a nonreceptor tyrosine kinase of unknown function.

174 Nonreceptor tyrosine kinases of the Src family are large

175 We found that BLK--a nonreceptor tyrosine-kinase of the src family of proto-o

176 The nonreceptor tyrosine kinase (p60src) is implicated in L1

177 The integrin-signaling nonreceptor tyrosine kinase, p72Syk, was activated in PM

178 Members of the JAK family of nonreceptor tyrosine kinases play a critical role in the

179 In attempts to determine whether nonreceptor tyrosine kinases play a fundamental role in

180 The Jak (Janus) family of nonreceptor tyrosine kinases plays a critical role in cy

181 The nonreceptor tyrosine kinase pp60(c-src) was required for

182 isolate the src homology (SH2) domain of the nonreceptor tyrosine kinase pp60c-src and beta-lactamase

183 rylation also required the activation of Src nonreceptor tyrosine kinase: pretreatment of cells with

184 inhibit the kinase activity of a receptor or nonreceptor tyrosine kinase, preventing downstream signa

185 Src, a nonreceptor tyrosine kinase proto-oncogene, reportedly m

186 The nonreceptor tyrosine kinase, proto-oncogene cAbl is a su

187 been previously demonstrated, e.g., via the nonreceptor tyrosine kinase PYK2 and by Ca(2+)/calmoduli

188 e alpha5beta1 integrin and activation of the nonreceptor tyrosine kinase PYK2 by PKC, most likely PKC

189 this study, we investigated the role of the nonreceptor tyrosine kinase Pyk2 during HPV16 pseudoviri

190 this study, we investigated the role of the nonreceptor tyrosine kinase Pyk2 during human papillomav

191 The nonreceptor tyrosine kinase Pyk2 is highly expressed in

192 KC), intracellular Ca(2+) ([Ca(2+)](i)), and nonreceptor tyrosine kinases Pyk2 and Src play in the ac

193 w that concomitant targeting of EGFR and the nonreceptor tyrosine kinases PYK2/FAK synergistically in

194 n 120 (gp120) induces phosphorylation of the nonreceptor tyrosine kinase, Pyk2.

195 Abl family nonreceptor tyrosine kinases regulate cellular morphogen

196 The c-Abl nonreceptor tyrosine kinase regulates actin responses in

197 Focal adhesion kinase (FAK) is an essential nonreceptor tyrosine kinase regulating cell migration, a

198 pyrimidine (PP1), suggesting that Src family nonreceptor tyrosine kinases represent a point of conver

199 ncentrate on Spleen tyrosine kinase (Syk), a nonreceptor tyrosine kinase required to transduce BCR-de

200 in ligase activity that targets receptor and nonreceptor tyrosine kinases, resulting in their ubiquit

201 Expression of v-Src, a transforming nonreceptor tyrosine kinase, results in Ras activation,

202 the expression pattern of the Src family of nonreceptor tyrosine kinases (SFK) in mouse embryonic st

203 RY)2 as a negative regulator of receptor and nonreceptor tyrosine kinase signaling in the pathogenesi

204 2, adaptors that normally integrate receptor/nonreceptor tyrosine kinase signaling into PI3K/AKT, rev

205 uld significantly decrease activation of the nonreceptor tyrosine kinase Src and activation of cAbl i

206 In the case of the membrane-bound nonreceptor tyrosine kinase Src from Rous sarcoma virus,

207 The nonreceptor tyrosine kinase Src has been implicated in t

208 Previously, we established a role for the nonreceptor tyrosine kinase Src in signaling cardiac myo

209 The nonreceptor tyrosine kinase Src is expressed at a high l

210 We report that the nonreceptor tyrosine kinase Src phosphorylates botulinum

211 cogenic potential of Ras is dependent on the nonreceptor tyrosine kinase Src to promote the Ras/Raf/M

212 to lipid rafts, where it interacts with the nonreceptor tyrosine kinase Src, is a prerequisite for f

213 ere, we show that PC1-p30 interacts with the nonreceptor tyrosine kinase Src, resulting in Src-depend

214 The nonreceptor tyrosine kinase Src, which has been associat

215 s the tyrosine phosphorylation of Akt by the nonreceptor tyrosine kinase Src, which is critical for A

216 t post-VEGF receptor levels and involves the nonreceptor tyrosine kinase Src.

217 e inhibitors, and specific inhibitors of the nonreceptor tyrosine kinase Src.

218 l membrane targeting domain, mediated by the nonreceptor tyrosine kinase Src.

219 The nonreceptor tyrosine kinases Src and FAK regulate focal-

220 Here we provided evidence on the role of nonreceptor tyrosine kinase, Src, in hyperoxia-induced t

221 udies with genistein and PP2 showed that the nonreceptor tyrosine kinase, Src, is an upstream stimula

222 tified as an SH3/SH2 binding partner for the nonreceptor tyrosine kinase, Src.

223 hosphorylated mammalian Disabled can recruit nonreceptor tyrosine kinases, such as src and abl, to th

224 al growth factor receptor (EGF-R) as well as nonreceptor tyrosine kinases, such as Src, have been imp

225 We have identified the nonreceptor tyrosine kinase syk as a marker of different

226 The nonreceptor tyrosine kinase SYK has recently received a

227 rosine-based activation motif (ITAM) and the nonreceptor tyrosine kinase Syk.

228 es TNFalpha and IL1-beta was mediated by the nonreceptor tyrosine kinase, Syk.

229 tion that encodes a constitutively activated nonreceptor tyrosine kinase termed P210(BCR-ABL).

230 Jak2 is a nonreceptor tyrosine kinase that acts in numerous cellul

231 ACK1 is a nonreceptor tyrosine kinase that associates specifically

232 Src is a nonreceptor tyrosine kinase that coordinates responses t

233 ted Cdc42-associated tyrosine kinase-2) is a nonreceptor tyrosine kinase that is a specific target/ef

234 c-Abl is a nonreceptor tyrosine kinase that is activated by certain

235 Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that is activated by integri

236 p56lck is a nonreceptor tyrosine kinase that is essential for signal

237 Spleen tyrosine kinase (Syk) is a nonreceptor tyrosine kinase that is expressed primarily

238 Brk (breast tumor kinase) is a nonreceptor tyrosine kinase that is most closely related

239 Breast tumor kinase (Brk) is a nonreceptor tyrosine kinase that is overexpressed in a h

240 C-Abl is a nonreceptor tyrosine kinase that is tightly regulated in

241 PEAK1 is a 190-kDa nonreceptor tyrosine kinase that localizes to actin fila

242 e H2O2-dependent phosphorylation of c-Abl, a nonreceptor tyrosine kinase that modulates the actin cyt

243 Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that on activation generates

244 Ack1 is a nonreceptor tyrosine kinase that participates in tumorig

245 Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that plays a critical role i

246 Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that plays an important role

247 Y245 phosphorylation of endogenous c-Abl, a nonreceptor tyrosine kinase that reciprocally regulates

248 Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that regulates cell signalin

249 In this study, we focused on JAK3, the nonreceptor tyrosine kinase that signals from the IL-2R,

250 c-Abl is a nonreceptor tyrosine kinase that we have recently linked

251 longs to a new group of structurally related nonreceptor tyrosine kinases that also includes Btk and

252 Syk and ZAP-70 form a subfamily of nonreceptor tyrosine kinases that contain tandem SH2 dom

253 and Arg proteins comprise a unique family of nonreceptor tyrosine kinases that have been implicated i

254 inase (Brk) is a member of the Frk family of nonreceptor tyrosine kinases that is overexpressed in a

255 ndocytosis of cell-surface receptors and Abl nonreceptor tyrosine kinases that participate in actin c

256 Abl and Arg define a family of nonreceptor tyrosine kinases that regulate actin-depende

257 l and the Abl-related gene product (Arg) are nonreceptor tyrosine kinases that regulate the actin cyt

258 g in transgenic mice deficient in a specific nonreceptor tyrosine kinase (the fyn mutant).

259 n alpha3 interacts functionally with the Arg nonreceptor tyrosine kinase to activate p190RhoGAP, whic

260 gnal through the Abl2/Arg (Abl-related gene) nonreceptor tyrosine kinase to control fibroblast cell m

261 to-oncogene (MET) through SRC proto-oncogene nonreceptor tyrosine kinase to maximize cellular invasio

262 s are responsible for the attachment of this nonreceptor tyrosine kinase to the membrane-solution int

263 ons show that TNFR1 associates with and uses nonreceptor tyrosine kinases to engage signaling pathway

264 ransduction from growth factor receptors and nonreceptor tyrosine kinases to Ras.

265 e SH2 domains are positive regulators of the nonreceptor tyrosine kinases, we tested whether this put

266 The Crk SH2/SH3 adaptor and the Abl nonreceptor tyrosine kinase were first identified as onc

267 the role of spleen tyrosine kinase (SYK), a nonreceptor tyrosine kinase, which has a central modulat

268 en tyrosine kinase (Syk) is an intracellular nonreceptor tyrosine kinase, which has been implicated a

269 Jak (Janus kinase) is a nonreceptor tyrosine kinase, which plays important roles

270 e inhibitor p27Kip1 on a tyrosine residue by nonreceptor tyrosine kinases, which decreases p27 stabil

271 ism of STAT3 activation by the Src family of nonreceptor tyrosine kinases, which have been linked to

272 is coupled either directly or indirectly to nonreceptor tyrosine kinases, which phosphorylate and th

273 The protooncogene c-abl encodes a nonreceptor tyrosine kinase whose cellular function is u

274 Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase whose focal adhesion targeti

275 Janus kinases (JAKs) are nonreceptor tyrosine kinases with a tandem pseudokinase-