ライフサイエンスコーパス: nonselective

1 e integrating into host chromosomes is locus nonselective.

2 in production but is generally thought to be nonselective.

3 in degradation, however, is considered to be nonselective.

4 Ins2(Akita/+) mice exhibited a nonselective 40% loss in sensitivity to all spatial freq

5 The nonselective 5-HT2 receptor agonist mCPP (0.0, 0.3, 1.0,

6 ons in 5alphaR1 activity in obesity and with nonselective 5alpha-reductase inhibition in men with pro

7 The nonselective 5alpha-reductase inhibitor finasteride indu

8 pha-blockers preoperatively (selective, 587; nonselective, 627; both, 40).

9 as the dose-limiting toxicity caused by the nonselective action on normal tissues by such drugs.

10 btypes, i.e., many antagonists considered as nonselective actually are beta3-sparing, including propr

11 g A2A and A2B receptor transcripts, only the nonselective adenosine agonist NECA (5'-N-ethylcarboxami

12 quired primarily A(2B) receptors because the nonselective adenosine receptor agonist 5'-N-ethylcarbox

13 Because caffeine (a nonselective adenosine receptor antagonist) and selectiv

14 st commonly ingested psychoactive drug and a nonselective adenosine receptor antagonist, alters CB fu

15 lays the desired profile in vitro with high, nonselective affinity for the MOP, KOP, and DOP receptor

16 izations of 1,2-bis(2-nitroaryl)ethenes were nonselective, affording mixtures of monocyclized indoles

17 ere we report fluorescent derivatives of the nonselective agent asenapine which were designed, synthe

18 h cox-2>cox-1 inhibition (eg, naproxen), and nonselective agents with cox-1>cox-2 inhibition (eg, ibu

19 Nonselective agents with cox-1>cox-2 inhibition were not

20 selective cox-2 inhibitors (eg, celecoxib), nonselective agents with cox-2>cox-1 inhibition (eg, nap

21 The strong induction of ECM synthesis by the nonselective agonists S1P and FTY720-P was due to the st

22 lanthranilates in particular, are potent but nonselective AKR1C3 inhibitors.

23 Nonselective alpha- and beta-adrenergic antagonists or s

24 IS in all groups (those taking selective and nonselective alpha-antagonists and also those not taking

25 Nonselective alpha-antagonists caused IFIS at a higher p

26 The use of either selective or nonselective alpha-antagonists preoperatively demonstrat

27 TPC1 is selective for Ca(2+) over Na(+), but nonselective among monovalent cations (Li(+), Na(+), and

28 ase chain reaction (TOP-PCR) for full-length nonselective amplification of minute quantity of DNA fra

29 mization and fine-tuning of quantitative and nonselective analysis of O-linked glycans released from

30 olving this pathway, but current methods are nonselective and are not applicable to measurement of th

31 al transient receptor potential 6 (TRPC6), a nonselective and Ca(2+)-permeable cation channel, mediat

32 = 5) and omega-agatoxin-IVA (100 nM, n = 3), nonselective and Cav2.1 Ca(2+) channel blockers, respect

33 have found that the RHOGAP domain itself is nonselective and in some cases rather inefficient under

34 to the bioceramics induced a decrease in the nonselective and integrin-selective binding of human ser

35 gy, resulting in a robust protocol which was nonselective and reproducible (the overall success ident

36 Notably, the Sq dye in solution state is nonselective and responds to any thiol-containing protei

37 S. aureus was isolated using nonselective and selective media.

38 ng through the Golgi and is involved in both nonselective and selective types of autophagy, whereas t

39 at lateralis synaptogenesis is intrinsically nonselective and that interaxonal interactions continuou

40 n administered in the presence of estradiol (nonselective) and genistein (ERbeta-selective), respecti

41 tes to thionated NDIs are generally lengthy, nonselective, and low yielding and their polymeric analo

42 Because many fishing gears are nonselective, and the costs of making gear selective can

43 A neutralizing antiserum against AnxA1 and a nonselective antagonist of AnxA1 receptor abolished the

44 xA1 pathway (by using N-t-Boc-Met-Leu-Phe, a nonselective AnxA1 receptor antagonist, or by using an a

45 these discrepancies can be explained by the nonselective application of relative perfusion threshold

46 Unlike nonselective approaches targeting the entire T cell popu

47 We showed that injection of mice with a nonselective AR agonist, 5'-N-ethylcarboxamidoadenosine

48 Although previous, nonselective attenuation of CRH production or action, ge

49 the generation of intensity selectivity from nonselective auditory nerve inputs remain largely unclea

50 some fusion events controlling selective and nonselective autophagy pathways.

51 critical role in the efficient induction of nonselective autophagy.

52 s specifically involved in mitophagy but not nonselective autophagy.

53 ying the onset of AD and could be safer than nonselective BACE inhibitor drugs.

54 und to be RAN-preferring, SEQ-preferring, or nonselective based on total firing rate.

55 ant antihyperalgesia cannot be achieved with nonselective BDZs.

56 Nonselective beta blockers (NSBBs) reduce portal pressur

57 ophylaxis of esophageal variceal bleeding is nonselective beta blockers.

58 10 lean men during systemic infusion of the nonselective beta-agonist isoprenaline (ISO) and compare

59 olled study to assess the effects of chronic nonselective beta-blockade in asthma, showing no signifi

60 Early and long-term nonselective beta-blockade was associated with adverse l

61 The nonselective beta-blocker propranolol has become first-l

62 Carvedilol, a currently prescribed nonselective beta-blocker, has been classified as a beta

63 Carvedilol, a nonselective beta-blocker, may be more effective than th

64 Nonselective beta-blockers (NSBB) are widely used becaus

65 At these earlier stages, nonselective beta-blockers (NSBBs) have been ineffective

66 The safety of nonselective beta-blockers (NSBBs) in advanced cirrhosis

67 Nonselective beta-blockers are useful to prevent bleedin

68 Those who respond to nonselective beta-blockers have a predictable overall lo

69 nsity, and increased survival of patients on nonselective beta-blockers.

70 nt receptor potential channel 5 (TRPC5) is a nonselective, Ca(2+)-permeable cation channel that belon

71 ient receptor potential channel family, is a nonselective calcium channel.

72 ining natural product identified as a potent nonselective, calpain inhibitor, with demonstrated effic

73 However, the choice between targeted and nonselective campaigns should be context specific, achie

74 mbination of at least three effects: (1) the nonselective catalytic activity of the surface of the so

75 larization-activated cyclic nucleotide-gated nonselective cation (HCN) channels in rat layer 5B pyram

76 nerates a small-conductance Ca(2+)-activated nonselective cation (SCAN) current with subpicosiemens s

77 B and a small-conductance, Ca(2+)-activated, nonselective cation channel (SCAN), TMEM16F.

78 TRPM8, a nonselective cation channel activated by cold, voltage,

79 receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel activated by multiple stimul

80 al Canonical 3 (TRPC3), a calcium-permeable, nonselective cation channel endowed with high constituti

81 receptor potential melastatin 8 (TRPM8) is a nonselective cation channel expressed in a subpopulation

82 ining fluid homeostasis, AQP1 also acts as a nonselective cation channel gated by cGMP, a property sh

83 channel, and under permissive conditions, a nonselective cation channel gated by cGMP.

84 ansient receptor potential ankyrin 1 (TRPA1) nonselective cation channel has a conserved function as

85 To understand how, we focus on TRPV4, a nonselective cation channel highly expressed in epitheli

86 P2X4 is an ATP-gated nonselective cation channel highly permeable to calcium.

87 cystin-2 (PC2, TRPP2) is a Ca(2+)-permeable, nonselective cation channel implicated in Ca(2+) transpo

88 Plant TPC1 functions as a nonselective cation channel on the vacuole membrane, whe

89 hodopsin 2 (ChR-2), a direct light-activated nonselective cation channel originally discovered in Chl

90 We found that the mechanically activated nonselective cation channel Piezo2 was expressed in sens

91 nt receptor potential vanilloid 1 (TRPV1), a nonselective cation channel present on most afferents.

92 The P2X7 receptor (P2X7R) is an ATP-gated nonselective cation channel that induces inflammatory re

93 melastatin 3 (TRPM3) is a calcium-permeable nonselective cation channel that is expressed in a subse

94 TRPA1 is a nonselective cation channel that is expressed in peptide

95 annelrhodopsin-2 (ChR2) is a light-activated nonselective cation channel that is found in the eyespot

96 ember 1 (TRPV1) or vanilloid receptor 1 is a nonselective cation channel that is involved in the dete

97 nsient receptor potential channel TRPP2 is a nonselective cation channel that is mutated in autosomal

98 nt receptor potential channel 1 (TRPC1) is a nonselective cation channel that is required for Ca(2+)

99 Here, we evaluated the nonselective cation channel transient receptor potential

100 The nonselective cation channel transient receptor potential

101 ansient receptor potential superfamily, is a nonselective cation channel with Ca(2+) permeability.

102 TRPM7 encodes a Ca2+-permeable nonselective cation channel with kinase activity.

103 cellular constriction point in the bacterial nonselective cation channel, NaK.

104 y, and a small-conductance calcium-activated nonselective cation channel, TMEM16F, linked to Scott sy

105 r has been coupled to hyperactivation of the nonselective cation channel, transient receptor potentia

106 ubfamily C, member 6 (TRPC6) gene encoding a nonselective cation channel.

107 tute Ca2+ -activated, but Ca2+ -impermeable, nonselective cation channels and are expressed both in a

108 nonical transient receptor potential (TRPC3) nonselective cation channels are effectors of G-protein-

109 tor Potential Canonical (TRPC) proteins form nonselective cation channels commonly known to be activa

110 Several different nonselective cation channels contribute to pressure-indu

111 P2X7 receptors are nonselective cation channels gated by high extracellular

112 by which a local Ca(2+) signal generated by nonselective cation channels stimulates TMEM16A channels

113 tential (TRPC) channels are Ca(2+)-permeable nonselective cation channels that are activated by a wid

114 ptor potential vanilloid 4 (TRPV4) channels--nonselective cation channels with considerable Ca(2+) co

115 clic nucleotide-gated (CNG) ion channels are nonselective cation channels, essential for visual and o

116 sequence identity and form Ca(2+)-permeable nonselective cation channels.

117 he opening of cyclic-nucleotide-gated (CNG), nonselective cation channels.

118 ial vanilloid 1) proteins are heat-activated nonselective cation channels.

119 ata suggest a key role of a Ca(2+)-activated nonselective cation conductance ((CaN)) in generating th

120 of inward and outward currents mediated by a nonselective cation conductance and a calcium-activated

121 a S2 cells induces an L-canavanine-activated nonselective cation conductance.

122 In whole-cell recordings, IgG-IC induced a nonselective cation current (I(IC)) in the rat DRG neuro

123 hat blue light (470 nm) elicited the typical nonselective cation current of ChR-2 with reversal poten

124 Muscarinic stimulation activated a small nonselective cation current so that total membrane curre

125 PV4 agonist GSK1016790A (GSK101) activated a nonselective cation current, robustly elevated [Ca(2+) ]

126 undantly expressed TRPC3 and had appreciable nonselective cation currents (I(NSC)) sensitive to a sel

127 Indeed, two nonselective cationic channels, TRPC3 and TRPC6, are ove

128 resting K(+) conductance and activation of a nonselective cationic conductance primarily mediated by

129 ve fuels was consistent with a decrease in a nonselective cationic conductance.

130 re found to be mediated by calcium-activated nonselective cationic current induced by transient inten

131 e-activated calcium channels (CaV) using the nonselective CaV blocker Cd(2+) or the specific N-type b

132 Paradoxically, the nonselective CB1/CB2 receptor agonist WIN55212 inhibited

133 ane channels; an open (hemi)channel is not a nonselective channel.

134 M induction via stretch-activation of cation-nonselective channels, with VF induction requiring PVEM

135 acological block of stretch-activated cation-nonselective channels.

136 ivated potassium or stretch-activated cation-nonselective channels.

137 phagy (hereafter autophagy) functions in the nonselective clearance of cytoplasm.

138 Nonselective clonotypic expansion was caused by relative

139 ionization with data-independent multiplexed nonselective collision induced dissociation (CID) on a t

140 oxylic acid (NTRC-739, 7b) starting from the nonselective compound 5a.

141 Eliminating the nonselective compounds did not change the clustering of

142 s allows mutation rates to be measured under nonselective conditions, as phenotypic reversion to fluo

143 suppress a latent state of unrestricted and nonselective consumption.

144 Quaternary Ammonium Herbicides (QUATs) are nonselective contact herbicides, widely used at weed eme

145 Administration of a nonselective COX inhibitor (indomethacin), selective COX

146 bition of PGE2 production with diclofenac, a nonselective COX inhibitor, resulted in reduced tumor gr

147 pholipase A2 (PLA2) inhibitor], ibuprofen [a nonselective COX inhibitor], neomycine [a phospholipase

148 th ICV and intra-dmPFC administration of the nonselective CRF antagonist, D-Phe-CRF, dose-dependently

149 ) or ventricular (1000 ng) injections of the nonselective CRF receptor antagonist D-Phe-CRF(12-41) de

150 d that an intracerebroventricularly injected nonselective CRF-R antagonist enhances, whereas an agoni

151 crease in hyperpolarization-activated cation nonselective current (I(h)) at the soma and dendrite.

152 tive sodium current and inhibits the outward nonselective current.

153 le(4)-c[Asp(5),D-Nal(2')(7),Lys(10)]-NH2), a nonselective cyclic peptide antagonist at hMC3R and hMC4

154 ensitive epithelial Na(+) channel (ENaC) and nonselective cyclic-nucleotide-gated cation channels cre

155 ienes (cysLTs), and respiratory reactions to nonselective cyclooxygenase (COX) inhibitors.

156 MCs), and bronchoconstriction in response to nonselective cyclooxygenase inhibitors that deplete home

157 Current inv(16) AML treatment with nonselective cytotoxic chemotherapy results in a good in

158 In addition, high affinity, nonselective D3 agonist (-)-19 (EC(50), D2 = 2.96 nM and

159 e the cardiovascular safety of alogliptin, a nonselective dipeptidyl peptidase 4 inhibitor.

160 as in absence of Mg(2+), CorA is essentially nonselective, displaying only mild preference against ot

161 ects of intra-accumbens core flupenthixol, a nonselective dopamine receptor antagonist, on context re

162 tively augment pulmonary vascular effects of nonselective drugs without the potentially problematic c

163 substrate mRNAs with nanomolar affinity in a nonselective fashion.

164 BET BD inhibitors (BETis) that are nonselective for BD1 or BD2 have recognized anti-inflamm

165 The nonselective Fpr agonists, fMLP (6 mug/mouse, approximat

166 ced lung fibrosis similar to that of a known nonselective galectin-1/galectin-3 inhibitor, which stro

167 iquid membrane contactor generally used as a nonselective gas absorption enhancement device is innova

168 The nonselective glucocorticoid receptor (GR) antagonist mif

169 rior efficacy had previously been noted with nonselective group II antagonists.

170 r)) isolates showed reduced resistance after nonselective growth, suggesting that mechanisms other th

171 of the resistance phenotype was scored after nonselective growth.

172 er with a single dose of lithium chloride (a nonselective GSK-3 inhibitor) or a preferential GSK-3bet

173 Many ion channels, both selective and nonselective, have reentrant pore loops that contribute

174 e form of hyperpolarization-activated cation-nonselective (HCN) channels as an active mechanism to co

175 echnologies have allowed the use of existing nonselective herbicides to be extended into crops.

176 Studies have shown that nonselective histone deacetylase (HDAC) inhibitors can p

177 y of anti-CD20 antibodies and confirmed with nonselective histone deacetylase inhibitors (HDACis).

178 ily, TRPM8 is the cold receptor that forms a nonselective homotetrameric cation channel.

179 ng use of alpha-blockers (both selective and nonselective), IFIS, intraoperative iris trauma, intraop

180 tence of a rapid subcortical pathway that is nonselective in terms of the spatial frequency or emotio

181 Importantly, nonselective inactivation of infralimbic neurons, using

182 cZ transgenic rats for activity-dependent or nonselective inactivation of neurons, respectively, whic

183 methanogenic community dynamics pointed to a nonselective influence of the different operational cond

184 We found that nonselective inhibition of Ca(2+) signaling strongly imp

185 e induction of sepsis, and comparison with a nonselective inhibitor (Nomega-nitro-L-arginine methyl e

186 Isoxicam is a nonselective inhibitor of COX-1 and COX-2 whereas meloxi

187 , similar to the effects of the PDE4 subtype nonselective inhibitor rolipram.

188 hat the aryl urea 1 is a modestly potent yet nonselective inhibitor.

189 onyl DKA derivatives were first described as nonselective inhibitors of 3'-processing (3'-P) and stra

190 duced cell death signaling; and that isoform nonselective inhibitors of TG will be most efficacious i

191 PDE4 subtype nonselective inhibitors produce potent antidepressant-li

192 ted by retinal horizontal cells that receive nonselective input from L and M cones.

193 rs and confirm that the majority of them are nonselective interference compounds.

194 utside the typical spectral bandwidth of the nonselective inversion pulse used in conventional LGE, w

195 pulse sequence was modified by replacing the nonselective inversion pulse with a wideband inversion p

196 mportant in enabling the transition from the nonselective ion channel mode to a membrane pore allowin

197 rstanding of ion permeation in selective and nonselective ion channels.

198 hat is also dependent on the activity of TRP nonselective ion channels.

199 otential of biocatalysis relative to mature (nonselective ion exchange, selective ion exchange, and w

200 higher in cost and environmental impact than nonselective ion exchange.

201 d currents composed of enhanced ICRAC plus a nonselective ISOC mediated by TRPC1.

202 necycloalkanones structurally related to the nonselective isopeptidase inhibitor G5 were synthesized

203 of two ion exchange (IX) technologies (i.e., nonselective IX with periodic regeneration using brines

204 s that brine is the dominant contributor for nonselective IX, which shows higher impact than perchlor

205 Nonselective (ketorolac tromethamine, ibuprofen, indomet

206 The nonselective kinase inhibitor staurosporine did not redu

207 receptor potential vanilloid 1 (TRPV1) is a nonselective ligand-gated cation channel responding to n

208 r potential TRPV1 or vanilloid receptor is a nonselective ligand-gated channel highly expressed in pr

209 tion in solution and gas phases by comparing nonselective lipid binding with soluble and membrane pro

210 t sites both in vivo and in vitro in a locus-nonselective manner.

211 specimens are subcultured onto selective and nonselective media, including 5% blood agar and TCBS aga

212 e, we evaluated the effect of doxycycline, a nonselective MMP inhibitor on CAVD progression in the mo

213 adiolabeled and unlabeled derivatives of the nonselective MMPIs, we discovered a new class of fluorin

214 Pretreatment with FTY720, an S1P-R1 nonselective modulator significantly reduced migration a

215 , tasimelteon and TIK-301, are high-affinity nonselective MT1/MT2 agonists.

216 rking in concert with megalin and cubilin, a nonselective multireceptor complex that predominantly di

217 al reports have revealed that scopolamine, a nonselective muscarinic acetylcholine receptor antagonis

218 ical studies demonstrate that scopolamine, a nonselective muscarinic acetylcholine receptor antagonis

219 g the cholinergic side effects observed with nonselective muscarinic orthosteric agonists.

220 Clinical evidence that ketamine, a nonselective N-methyl-D-aspartate receptor (NMDAR) antag

221 Neither the nonselective nAChR agonist nicotine nor the psychostimul

222 inding pockets identified previously for the nonselective nAChR PAMs galantamine and physostigmine at

223 Comparison of NMR spectra of the nonselective NaK and potassium-selective NaK2K indicates

224 ries, we obtained atomistic evidence for the nonselective nature of TRPV1.

225 The utility of nonselective Nav blockers is often limited due to advers

226 KB-R7943, a nonselective NCX3 blocker, reduced [Ca(2+)]r in both swi

227 igh-intensity levels compared with intensity-nonselective neurons.

228 tracranial microinfusions of mecamylamine, a nonselective nicotinic receptor antagonist, highlight a

229 CD69) and serves as a novel marker of early, nonselective NK cell activation.

230 Ms, CP101,606 and BMT-108908, along with the nonselective NMDA antagonists, ketamine and AZD6765, in

231 The nonselective NMDA receptor antagonist d,l-2-amino-5-phos

232 (n = 8) antagonists, along with vehicle and nonselective NMDA-R antagonists (ketamine, n = 10; MK801

233 patial working memory deficits caused by the nonselective NMDAR antagonist ketamine.

234 who take warfarin with antiplatelet drugs or nonselective nonsteroidal anti-inflammatory drugs (NSAID

235 scular safety of celecoxib, as compared with nonselective nonsteroidal antiinflammatory drugs (NSAIDs

236 study of cyclooxygenase 2 inhibitors versus nonselective nonsteroidal antiinflammatory medications i

237 hanism was assessed by pretreatment with the nonselective norepinephrine uptake-1 and norepinephrine

238 re retained in tumors for over 1 wk, whereas nonselective NPs were cleared within hours.

239 d the risk of UGIB during concomitant use of nonselective (ns)NSAIDs, cyclooxygenase -2 selective inh

240 tients with general asthma unwilling to risk nonselective NSAID exposure when oral challenge tests ar

241 All nonselective NSAIDs significantly accelerated mortality

242 egular use of selective cox-2 inhibitors and nonselective NSAIDs with cox-2>cox-1 inhibition showed a

243 Use of nonselective NSAIDs, either alone or as adjuncts to anti

244 m the spider Argiope lobata, is a potent but nonselective open-channel blocker of ionotropic glutamat

245 nd N-phenylpropyl substituted compounds were nonselective opioid antagonists (2) all N-phenylpropyl a

246 tion of a 7alpha-acylamino group to the pure nonselective opioid receptor antagonist N-phenylpropyl-4

247 nimals were injected daily with nalmefene, a nonselective opioid receptor antagonist, and infected by

248 , whereas past extinction events were either nonselective or preferentially removed smaller-bodied ta

249 of prostaglandin (PG) production with either nonselective or selective inhibitors of cyclooxygenase-2

250 ysis reveals that the SCN5A variant mediates nonselective outward currents and a small, but detectabl

251 nd H2 O2 generate hydroxyl radical, a strong nonselective oxidant of organic compounds.

252 4B should retain the therapeutic benefits of nonselective PDE4 inhibitors.

253 ristoylphosphatidylglycerol (DMPG) vesicles (nonselective peptides) or an intermolecular beta-sheet s

254 rast, rats in the contralateral group showed nonselective performance after devaluation indicating th

255 ith the presence of extrachromosomal DNA and nonselective persistence of plasmids in mammalian models

256 xpression through siRNA derepression or with nonselective pharmacologic inducers, including the CNS-p

257 vation during murine CMV (MCMV) infection: a nonselective phase mediated by proinflammatory cytokines

258 analysis of Tf1 integration events from the nonselective phase of the retrotransposition assay.

259 Ibudilast, a nonselective phosphodiesterase inhibitor, is used clinic

260 performed between rats to test the impact of nonselective (Piroxicam), preferential (Meloxicam), and

261 ct on RGS2 protein levels was blocked by the nonselective PKC inhibitor Go6983 (3-[1-[3-(dimethylamin

262 s, and have used the enzyme in tandem with a nonselective polymerase to locate the presence and posit

263 terials are replaced with laminar flow and a nonselective, porous convection barrier to separate the

264 udden cardiac death, but data on the role of nonselective post-mortem CIED (pacemaker or defibrillato

265 perennial race, recent climate conditions or nonselective processes, such as dispersal limitation or

266 Nonselective product formation was also observed from re

267 A nonselective propargylation of trifluoromethyl ketone 22

268 sis and ubiquitin recycling while preventing nonselective proteolysis, and the regulation of proteaso

269 d conjugate addition of a nickel hydride and nonselective protonation to release the substrate.

270 he probe was optimized from a weakly potent, nonselective pyridazinone hit to deliver high potency fo

271 at underlie the selective base-initiated and nonselective radical-mediated thiol-ene/yne reactions.

272 on of As(III) by PMS avoids the formation of nonselective reactive radicals, thus minimizing the adve

273 e disease without the pleiotropic effects of nonselective reagents and, thus, could be applicable to

274 r K(+) for Cs(+) is nearly thermodynamically nonselective, recent experiments show that direct, anhyd

275 related resting activity in the striatum and nonselective reduction in striatal inhibition synchroniz

276 tion (based on stereoselective oxidation and nonselective reduction).

277 this procedure is superior for quantitative nonselective release of O-glycans.

278 Finally, pharmacologic treatment with the nonselective S1P receptor agonist FTY720 causes increase

279 d metabolite of fingolimod was found to be a nonselective S1P receptor agonist, agonism specifically

280 ing MH pathophysiology by demonstrating that nonselective sarcolemmal cation channel activity plays a

281 enous infusion of psilocybin--prodrug of the nonselective serotonin 2A receptor agonist and classic p

282 ults on preclinical testing of selective and nonselective single compounds in orthotopic mouse models

283 sirtuin activity, we previously identified a nonselective sirtuin inhibitor called cambinol (IC50 app

284 Clinical utility of nonselective sodium channel blockers is limited due to s

285 nediol, monodihydrogen phosphate ester) is a nonselective sphingosine-1-phosphate (S1P) receptor agon

286 s revealed that mephedrone and methylone are nonselective substrates for plasma membrane monoamine tr

287 metals is prevented by chemical blocking of nonselective surface adsorption sites.

288 the inhibition of AA or 2-AG oxygenation by nonselective time-dependent inhibitors.

289 Similarly, DNCB activated nonselective TRPA1 current in patch clamp studies.

290 The nonselective TrpC channel inhibitors SKF96365 and 2-APB

291 edia were compared to suspicious colonies on nonselective TSA II.

292 However, the inefficient and nonselective uptake of these agents by tumor cells compr

293 esulted from off-target actions of Cd(2+), a nonselective VACC blocker, or other variations in experi

294 in mouse neocortical neurons, selective and nonselective VACC blockers inhibit spontaneous release a

295 ty antagonist of the prokaryotic NaVs NsVBa (nonselective voltage-gated Bacillus alcalophilus) and Na

296 However, nonselective, widespread PSA-testing followed by liberal

297 the widely used KCC2 inhibitor furosemide is nonselective with antiseizure efficacy in slices and in

298 n campaigns in measles outbreak response are nonselective with respect to the immune status of indivi

299 molecular design and synthesis of potent but nonselective zinc-chelating MMP inhibitors (e.g., 10a an

300 ontrast to the Notch cofactor Maml, which is nonselective, Zmiz1 was selective.