ライフサイエンスコーパス: nonselective cation channel

1 The membrane form of TRPV1 functions as a nonselective cation channel.

2 wever, membrane stretch can activate a 21-pS nonselective cation channel.

3 ndependent Ca(2+) entry in TRPC6 cells via a nonselective cation channel.

4 m), which is compatible with activation of a nonselective cation channel.

5 lyzes cGMP, and that cGMP directly gates the nonselective cation channel.

6 ubfamily C, member 6 (TRPC6) gene encoding a nonselective cation channel.

7 scribe the semisynthesis of NaK, a bacterial nonselective cation channel.

8 otein expression of TRPM2, a Ca2+-permeable, nonselective cation channel.

9 members, NALCN forms a voltage-independent, nonselective cation channel.

10 sure rapid and efficient activation of these nonselective cation channels.

11 of the vanilloid type of TRP superfamily of nonselective cation channels.

12 ial vanilloid 1) proteins are heat-activated nonselective cation channels.

13 or internal Ca2+, features typical of Na+/K+ nonselective cation channels.

14 ral gene with the genes encoding the related nonselective cation channels.

15 otential near 0 mV suggesting involvement of nonselective cation channels.

16 low-affinity receptors also associated with nonselective cation channels.

17 olar cell transmitter glutamate, which opens nonselective cation channels.

18 sequence identity and form Ca(2+)-permeable nonselective cation channels.

19 ls TRPML2 and TRPML3 (MCOLN2 and MCOLN3) are nonselective cation channels.

20 um/calcium exchanger and possibly opening of nonselective cation channels.

21 he opening of cyclic-nucleotide-gated (CNG), nonselective cation channels.

22 and by flufenamic acid, a blocker of Cl- and nonselective cation channels.

23 TRPM8, a nonselective cation channel activated by cold, voltage,

24 TRP) subfamily, TRPA1, is a Ca(2+)-permeable nonselective cation channel activated by electrophilic c

25 ssed in skin keratinocytes, where it forms a nonselective cation channel activated by hot temperature

26 receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel activated by multiple stimul

27 TRPC5 channels are Ca(2+)-permeable nonselective cation channels activated by G-protein-coup

28 Cyclic nucleotide-gated channels are nonselective cation channels activated by intracellular

29 K(Ca) and Cl(-) currents in macrophages, but nonselective cation channel activation was unique to gp1

30 , hyperpolarizes On bipolar cells by closing nonselective cation channels, an effect mediated by the

31 uired the cytoskeleton and the activity of a nonselective cation channel and the epithelial sodium ch

32 uces the activity of PC2, a Ca(2+)-permeable nonselective cation channel and, thus, limits the amplit

33 tute Ca2+ -activated, but Ca2+ -impermeable, nonselective cation channels and are expressed both in a

34 e data suggest two mechanisms, activation of nonselective cation channels and the sodium/calcium exch

35 ), IP(3) receptors, diacylglycerol-activated nonselective cation channels, and Ca(2+)-activated chlor

36 nonical transient receptor potential (TRPC3) nonselective cation channels are effectors of G-protein-

37 These nonselective cation channels are inhibited by local anes

38 These nonselective cation channels are permeable to Na(+) and

39 Thus, 3-pS nonselective cation channels are present and activated b

40 nsing receptor (CaSR) which in turn inhibits nonselective cation channels at the majority of cortical

41 t Ca(2+) chelator, and Gd(3+) and SKF-96365, nonselective cation channel blockers.

42 Ca2+ stores, and maitotoxin, an activator of nonselective cation channels, both converted the glucose

43 tor Potential Canonical (TRPC) proteins form nonselective cation channels commonly known to be activa

44 Several different nonselective cation channels contribute to pressure-indu

45 ptors that are part of or closely coupled to nonselective cation channels directly gated by low conce

46 al Canonical 3 (TRPC3), a calcium-permeable, nonselective cation channel endowed with high constituti

47 clic nucleotide-gated (CNG) ion channels are nonselective cation channels, essential for visual and o

48 TRPA1 is a nonselective cation channel expressed by nociceptors.

49 receptor potential melastatin 8 (TRPM8) is a nonselective cation channel expressed in a subpopulation

50 t receptor potential melastatin 8 (TRPM8), a nonselective cation channel expressed on a subset of per

51 TRP vanilloid 2 (TRPV2) is a nonselective cation channel expressed prominently in med

52 TRPC6 is a receptor-activated nonselective cation channel expressed widely in vascular

53 Thus, NALCN, a nonselective cation channel, forms the background Na(+)

54 opus oocytes provides a voltage-insensitive, nonselective cation channel function with permeability t

55 Unlike the other four members which are nonselective cation channels functioning as heat or osmo

56 ining fluid homeostasis, AQP1 also acts as a nonselective cation channel gated by cGMP, a property sh

57 channel, and under permissive conditions, a nonselective cation channel gated by cGMP.

58 ons express the vanilloid receptor, TRPV1, a nonselective cation channel gated by vanilloid ligands s

59 P2X7 receptors are nonselective cation channels gated by high extracellular

60 ansient receptor potential ankyrin 1 (TRPA1) nonselective cation channel has a conserved function as

61 Cyclic-nucleotide-activated, nonselective cation channels have a central role in sens

62 To understand how, we focus on TRPV4, a nonselective cation channel highly expressed in epitheli

63 P2X4 is an ATP-gated nonselective cation channel highly permeable to calcium.

64 , CG6504), which encodes a Ca(2+)-activated, nonselective cation channel homologous to the human Pkd2

65 Hyperpolarization-activated nonselective cation channels (Ih channels) play an impor

66 cystin-2 (PC2, TRPP2) is a Ca(2+)-permeable, nonselective cation channel implicated in Ca(2+) transpo

67 TRPA1 is an excitatory, nonselective cation channel implicated in somatosensory

68 nonical (TRPC) channels are Ca(2+)-permeable nonselective cation channels implicated in diverse physi

69 annels in cultured neocortical neurons and a nonselective cation channel in Jurkat T cells that is ac

70 We previously identified a novel, nonselective cation channel in native reactive (type R1)

71 annel in the endoplasmic reticulum, and/or a nonselective cation channel in the plasma membrane.

72 erfamily and has been shown to function as a nonselective cation channel in the plasma membrane.

73 sium (K(Ca)), chloride, and calcium-permeant nonselective cation channels in macrophages.

74 ediates M2 receptor coupling to metabotropic nonselective cation channels in mammalian smooth muscle

75 C heteromers form diverse receptor-regulated nonselective cation channels in the mammalian brain.

76 ole of a polycystin-1 protein (components of nonselective cation channels) in a specific cellular pro

77 The authors identified mutations in TRPM4--a nonselective cation channel--in a large family with prog

78 by glutamate released from photoreceptors, a nonselective cation channel is inhibited, causing these

79 Patch-clamp experiments show that a nonselective cation channel is stimulated by H(2)O(2) an

80 f its members, TRPM8 (CMR1), a ligand-gated, nonselective cation channel, is activated by both cold a

81 denosine 5'-diphosphoribose (ADPR)-activated nonselective cation channel, is also expressed in human

82 Nonselective cation channels may play a role in insulin

83 m, whereby gating of TRPM7, a Ca2+-permeable nonselective cation channel, mediates Ca2+ overload and

84 TRPC3 is a nonselective cation channel member of the "canonical" tr

85 These channels seem to be nonselective cation channels; monovalent cations are the

86 cellular constriction point in the bacterial nonselective cation channel, NaK.

87 on channels, such as outward K+ channels and nonselective cation channels (NCC).

88 des evidence for a novel, voltage-dependent, nonselective cation channel (NSCC) in the heart.

89 n the activation of novel (calcium-permeant) nonselective cation channels (NSCCs) and calcium release

90 y murine B cells reveal that Ca(2+)-permeant nonselective cation channels (NSCCs) operate in a cooper

91 ives, is a candidate for the store-operated, nonselective cation channels observed in smooth muscle c

92 Plant TPC1 functions as a nonselective cation channel on the vacuole membrane, whe

93 hodopsin 2 (ChR-2), a direct light-activated nonselective cation channel originally discovered in Chl

94 Activation of a nonselective cation channel, Pcat, was considered the ke

95 We found that the mechanically activated nonselective cation channel Piezo2 was expressed in sens

96 toxin, palytoxin, converts Na+/K+ pumps into nonselective cation channels, possibly by disrupting the

97 Transient Receptor Potential A1 (TRPA1) is a nonselective cation channel, preferentially expressed on

98 nt receptor potential vanilloid 1 (TRPV1), a nonselective cation channel present on most afferents.

99 tor potential melastatin type 8 (TRPM8) is a nonselective cation channel primarily expressed in a sub

100 the swelling-activated and stretch-activated nonselective cation channel response to strain.

101 tive strain by activating stretch-activated, nonselective cation channels (SA-CAT) and increasing mat

102 B and a small-conductance, Ca(2+)-activated, nonselective cation channel (SCAN), TMEM16F.

103 nsient receptor potential (TRP) channels are nonselective cation channels, several of which are expre

104 to its behavior as an outwardly rectifying, nonselective cation channel, shares many functional and

105 otential channel (TRPC)-related genes encode nonselective cation channels, some of which are similar

106 by which a local Ca(2+) signal generated by nonselective cation channels stimulates TMEM16A channels

107 channel, subfamily V, member 1 (TRPV1) is a nonselective cation channel that can be activated by a w

108 ignated TRPC7 or LTRPC2) is a Ca2+-permeable nonselective cation channel that contains a C-terminal e

109 The P2X7 receptor (P2X7R) is an ATP-gated nonselective cation channel that induces inflammatory re

110 The capsaicin receptor (TRPV1) is a nonselective cation channel that integrates multiple pai

111 The vanilloid receptor (VR1) is a nonselective cation channel that is activated by capsaic

112 In heterologous cell types it forms a nonselective cation channel that is activated by intrace

113 ry receptor neurons in the lobster express a nonselective cation channel that is activated by intrace

114 nsient receptor potential channel TRPV3 is a nonselective cation channel that is activated by warm te

115 nsient receptor potential channel TRPV3 is a nonselective cation channel that is activated by warm te

116 The capsaicin receptor (TRPV1) is a nonselective cation channel that is activated in nocicep

117 id receptor type 1 (TRPV1) is a ligand-gated nonselective cation channel that is considered to be an

118 , also known as TRPV1) is a thermosensitive, nonselective cation channel that is expressed by capsaic

119 melastatin 3 (TRPM3) is a calcium-permeable nonselective cation channel that is expressed in a subse

120 TRPA1 is a nonselective cation channel that is expressed in peptide

121 Vanilloid receptor subtype-1 (VR1) is a nonselective cation channel that is expressed in sensory

122 annelrhodopsin-2 (ChR2) is a light-activated nonselective cation channel that is found in the eyespot

123 in excised patches showed that TRPM5 forms a nonselective cation channel that is half-activated by 8

124 ial channel 2 (TRPM2) is a Ca(2+)-permeable, nonselective cation channel that is involved in oxidativ

125 ember 1 (TRPV1) or vanilloid receptor 1 is a nonselective cation channel that is involved in the dete

126 e cells have a second type of Ca2+-activated nonselective cation channel that is less sensitive to in

127 The vanilloid receptor VR1 is a nonselective cation channel that is most abundant in per

128 nsient receptor potential channel TRPP2 is a nonselective cation channel that is mutated in autosomal

129 how that polycystin-L is a calcium-modulated nonselective cation channel that is permeable to sodium,

130 ceptor-1 (VR1 or TRPV1) is a membrane-bound, nonselective cation channel that is predominantly expres

131 nt receptor potential channel 1 (TRPC1) is a nonselective cation channel that is required for Ca(2+)

132 canonical-1) channel is a constituent of the nonselective cation channel that mediates Ca2+ entry thr

133 The transient receptor potential TRPV1 is a nonselective cation channel that mediates pain sensation

134 It is a nonselective cation channel that prefers Ca2+ over Na+.

135 TRPM4 is a Ca(2+)-activated nonselective cation channel that regulates membrane pote

136 tential (TRPC) channels are Ca(2+)-permeable nonselective cation channels that are activated by a wid

137 tor potential (TRP) ion channel subtypes are nonselective cation channels that can be activated by in

138 The nonselective cation channels that carry this current hav

139 Animal CNGCs are nonselective cation channels that do not discriminate be

140 sists of a family of seven membrane-spanning nonselective cation channels that have been implicated i

141 Capsaicin receptor channels (TRPV1) are nonselective cation channels that integrate multiple nox

142 een defined as heat-sensitive, ligand-gated, nonselective cation channels that integrate nociceptive

143 TRPM7 channels are nonselective cation channels that possess a functional a

144 In a second example, expression of a nonselective cation channel, the influenza virus M2 prot

145 We recently identified a nonselective cation channel, the NC(Ca-ATP) channel, in

146 at sulfonylurea receptor 1 (SUR 1) regulated nonselective cation channel, the NC(Ca-ATP) channel, is

147 y, and a small-conductance calcium-activated nonselective cation channel, TMEM16F, linked to Scott sy

148 Here, we evaluated the nonselective cation channel transient receptor potential

149 The nonselective cation channel transient receptor potential

150 r has been coupled to hyperactivation of the nonselective cation channel, transient receptor potentia

151 The nonselective cation channel TRPA1 (ANKTM1, p120) is a po

152 These nonselective cation channels, underlying the I(f), I(h)

153 id not detect ENaC activity but did detect a nonselective cation channel upregulated by pioglitazone.

154 with the genes encoding the closely related, nonselective cation channels VR1, VRL-1, OTRPC4 (also kn

155 as a receptor-activated, calcium-permeable, nonselective cation channel when expressed in cell lines

156 y of proteins, functions as a Ca2+-modulated nonselective cation channel when expressed in Xenopus oo

157 5 is a member of the P2X family of ATP-gated nonselective cation channels, which exist as trimeric as

158 al melastatin-related channel 2 (TRPM2) is a nonselective cation channel, whose prolonged activation

159 nd TRPC5 in HEK293 cells resulted in a novel nonselective cation channel with a voltage dependence si

160 ansient receptor potential superfamily, is a nonselective cation channel with Ca(2+) permeability.

161 TRPM7 encodes a Ca2+-permeable nonselective cation channel with kinase activity.

162 TRPC are Ca(2+)-permeable, nonselective cation channels with a variety of physiolog

163 ces express both highly selective cation and nonselective cation channels with average conductances o

164 ptor potential vanilloid 4 (TRPV4) channels--nonselective cation channels with considerable Ca(2+) co

165 A separate class of nonselective cation channels, with a conductance of 50-6