ライフサイエンスコーパス: nonspecific

1 ray of immunotherapeutics, many of which are nonspecific.

2 Histologic features were nonspecific.

3 factors, and contributory etiologies remain nonspecific.

4 fatigue are sensitive (range, 0.81-0.83) but nonspecific.

5 ancer symptoms." However, these symptoms are nonspecific.

6 is common and clinical presentation is often nonspecific.

7 Clinical symptoms are nonspecific.

8 There was a nonspecific 3-mm right lower lobe pulmonary nodule.

9 he CNS, thereby limiting potentially harmful nonspecific Ab secretion.

10 h Nutcracker syndrome generally present with nonspecific abdominal pain, with the left renal vein (LR

11 o-subcortical pathways, cannot be reduced to nonspecific activation across motor structures.

12 Following nonspecific activation with the cytokines IL-12, IL-15,

13 This nonspecific activity was attenuated by mutations in the

14 Caffeine (5, 10, or 15 mg/kg), a nonspecific adenosine receptor antagonist, dose-dependen

15 Historically, accessibility relies upon the nonspecific adhesion of biomolecules to a surface and a

16 l assessments where inappropriate; not using nonspecific administrative secondary diagnosis codes to

17 le and susceptible to contamination owing to nonspecific adsorption and desorption on the substrate s

18 -peptide-based SPR sensors was their reduced nonspecific adsorption and enhanced sensitivity.

19 enging for precise gene delivery to overcome nonspecific adsorption and off-target effect.

20 cess to specific detection, we prevented the nonspecific adsorption of biomolecules present in saliva

21 immobilisation of antibodies while repelling nonspecific adsorption of other species.

22 The resulting substrates exhibit very low nonspecific adsorption, and the selectivity for binding

23 aluate strategies for preventing or removing nonspecific adsorption.

24 tabolites have been used with success, these nonspecific agents are not without their complications.

25 ve undergone a rapid evolution starting with nonspecific agents that accumulate similarly in infectio

26 ations in the ALPL gene, encoding the tissue-nonspecific alkaline phosphatase (ALP) enzyme.

27 loading of the calcification protein tissue nonspecific alkaline phosphatase (TNAP) into extracellul

28 eported that Fgf23 is a suppressor of tissue nonspecific alkaline phosphatase (Tnap) transcription vi

29 concentrations of Pi and PPi include tissue-nonspecific alkaline phosphatase (TNAP), progressive ank

30 ALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme expressed in

31 phosphate groups were globally reduced using nonspecific alkaline phosphatase, Triton X-100-solubiliz

32 ll lines were antigen-specific and showed no nonspecific alloreactivity in vitro and in vivo.

33 ess for pathogen-specificity and evidence of nonspecific alloreactivity.

34 These functions require high affinity for nonspecific amino acid sequences that are ubiquitous in

35 be specific for the detection of EBOV, as no nonspecific amplification was detected in blood samples

36 ssion of non-homologous primer annealing and nonspecific amplification.

37 The symptoms of Lassa fever can be nonspecific and mimic those of other endemic infections,

38 tations: its low brain permeability and high nonspecific and plasma binding results in a low signal-t

39 Differences between nonspecific and specific agents, due to specific tumor b

40 neumonia etiology studies include the use of nonspecific and variable case definitions, poor access t

41 isease (IBD) is difficult to diagnose due to nonspecific and variable symptoms, and lack of reliable

42 etry can be helpful, these are often costly, nonspecific, and unsuitable for evaluating programmatic

43 ut nonspecificity assay to isolate panels of nonspecific antibodies from two synthetic single-chain v

44 ntibody cocktails, increasing probability of nonspecific antibody binding, especially when multiplexi

45 iltration of dendritic and/or round cells; a nonspecific architectural pattern at the dermoepidermal

46 ulted not from hyperthermia per se, but from nonspecific aspects of the intervention.

47 More importantly, nonspecific attachment of 1,4,7-triazacyclononane-1,4,7-

48 cognition is often presumed to be relatively nonspecific, attributable to either a TCR focus on expos

49 bnormalities include hypergammaglobulinemia, nonspecific B cell activation, class switching, increase

50 mmunoCAP harbors residual N-glycans, causing nonspecific background binding in CCD-positive sera.

51 a solid supported membrane ensuring minimal nonspecific background interactions.

52 nce (MR) imaging have proven insensitive and nonspecific because both use nodal size criteria, which

53 oscopic variceal ligation, sclerotherapy, or nonspecific beta-blockade in children was proposed.

54 and extracellular nucleic acids exhibit both nonspecific binding and adverse effects on blood clottin

55 This ensures their responses to nonspecific binding and environmental changes are almost

56 chemically to pg/ml range with insignificant nonspecific binding and false signal in undiluted serum.

57 s sensitively to ng/ml range with negligible nonspecific binding and false signal in undiluted serum.

58 High nonspecific binding and low cellular uptake were observe

59 The two beta-catenin/BCL9 inhibitors had low nonspecific binding but different cellular uptake.

60 cts as a dynamic reference, compensating for nonspecific binding events and changes in the environmen

61 teractions to forces even in the presence of nonspecific binding events.

62 c radioligand (3)H-T808; second, by very low nonspecific binding in brain tissue devoid of tau pathol

63 itecture of antibodies, but also reduces the nonspecific binding in detecting multicomponent samples.

64 ability to distinguish between specific and nonspecific binding is important for assessing the inter

65 tein 18 kDa (TSPO) have been limited by high nonspecific binding of the first-generation radioligand,

66 hod is employed to quantify the specific vs. nonspecific binding of the multiplexed NPs.

67 of DNA chains interacting with a solution of nonspecific binding proteins, we implemented a Flory-Hug

68 ability to distinguish between specific and nonspecific binding remains a limitation.

69 Polybasic regions are often associated with nonspecific binding to acidic phospholipids including ph

70 ility and high basicity and demonstrate that nonspecific binding to lung tissue increases with lipoph

71 Nonspecific binding was prevented using starting block T

72 ncentrations, the cell permeability, and the nonspecific binding with the cell culture plates, the ex

73 um remains difficult due to Debye screening, nonspecific binding, and stringent functionalization req

74 e, and an assay property of newly discovered nonspecific binding.

75 20) blocking buffer was utilized to minimize nonspecific binding.

76 the spectra can differentiate specific from nonspecific binding.

77 h the cerebellum as the reference tissue for nonspecific binding.

78 Medical devices face nonspecific biofouling from proteins, cells, and microor

79 g experiments, as well as a high specific to nonspecific BRET binding signal.

80 presence of asthma through the assessment of nonspecific bronchial hyperresponsiveness (NSBH) is a ke

81 Here we show that nonspecific bystander inflammation conditions naive CD4(

82 erged granules had greater targeted and less nonspecific "bystander" killing.

83 raditional photoaffinity labels work through nonspecific C-H/X-H bond insertion reactions with the pr

84 Cyclic nucleotide-gated channels (CNGCs) are nonspecific, Ca(2+)-permeable cation channels.

85 ectrophoresis increased the specific and the nonspecific capture of immunobeads at the BD-UNCD electr

86 larization-activated cyclic-nucleotide-gated nonspecific-cation channels.

87 reased cell death, which also coincided with nonspecific cell death from photothermal heating.

88 the micromolar concentration range led to a nonspecific cell toxicity.

89 tic stem cells (HSCs) despite a reduction in nonspecific cellular toxicities.

90 To rule out a general, nonspecific change in space perception consequent the il

91 Nonspecific changes (vacuolization of tubular cells, los

92 The opening of a nonspecific channel, known as the permeability transitio

93 uman mitochondria refers to the opening of a nonspecific channel, known as the permeability transitio

94 ary reasons for visit were pneumonia (4.5%), nonspecific chest pain (3.7%), and urinary tract infecti

95 most common reasons for readmission included nonspecific chest pain/angina (24%) and heart failure (1

96 This implies that other enzymes or nonspecific chloroplast transporters could provide 3-pho

97 A manualized yoga program for nonspecific cLBP was noninferior to PT for function and

98 tly low-income, racially diverse adults with nonspecific cLBP.

99 Arg-C proteolysis, yet with fewer missed and nonspecific cleavages.

100 omas can occur in almost every organ, and if nonspecific clinical findings are combined with the pres

101 Diagnosing myocarditis is challenged by nonspecific clinical signs and symptoms and low accuracy

102 anisms to global regulation through a web of nonspecific competing interactions that modulate the opt

103 ation of such a thermodynamically stable but nonspecific complex is expected to slow down the rate of

104 t is not clear how this complex differs from nonspecific complexes.

105 Although nonspecific conjugation is suitable for most in vitro ap

106 soluble proteins, these complexes arise from nonspecific contacts between the protein and detergent/l

107 trode state or ionic environment, leading to nonspecific contributions to the FSCV data that confound

108 28H1 (anti-FAP antibody), respectively, with nonspecific controls included.

109 By overcoming the technical hurdle of nonspecific Cre-loxP-mediated recombination, this new te

110 onal; inconclusive serotyping results due to nonspecific cross-reactions; or novel genotypes.

111 d signaling, most likely by functioning as a nonspecific CXCR4 antagonist.

112 d to patients with MPN with eosinophilia and nonspecific cytogenetic/molecular abnormalities and/or i

113 ining effector T cell expansion and limiting nonspecific damage to the host.

114 rlier 100- to 500-mus step that we assign to nonspecific deformation (unwinding/"twisting") of DNA by

115 ed in few diseases besides psoriasis and (2) nonspecific DEGs similarly altered in many other skin co

116 cause the clinical presentation of dengue is nonspecific, dengue diagnosis would benefit from a sensi

117 distinguishing between disease-specific and nonspecific differentially expressed genes (DEGs).

118 method of limited proteolysis, which allows nonspecific digestion of unfolded peptides by trypsin.

119 t weak but physiologically relevant sequence-nonspecific DNA affinity.

120 DNA weakly and does not discriminate between nonspecific DNA and duplexes that contain the packaging

121 How ParA-ATP binds nonspecific DNA and is regulated by ParB is unclear.

122 y bound PU.1 dimer resisted competition from nonspecific DNA and showed affinities similar to other f

123 emonstrated that these properties are due to nonspecific DNA binding on its surface, along with a cat

124 the Miz-1 consensus sequence and preventing nonspecific DNA binding.

125 th the glycopeptide antibiotic phleomycin, a nonspecific DNA double strand breaker.

126 ponse element, a puma response element and a nonspecific DNA sequence.

127 otein does not induce appreciable bending of nonspecific DNA.

128 This effect is distinct from the nonspecific effect of behavioral activity on auditory re

129 g view considered neutrophils to function as nonspecific effector cells that die quickly after perfor

130 ets in vitro, while several also demonstrate nonspecific effects in cell assays.

131 The mechanisms behind these nonspecific effects of BCG are not fully understood, but

132 ithin a randomized trial designed to examine nonspecific effects of early MV receipt on mortality, we

133 f-generated sounds was not simply due to the nonspecific effects of movement or behavioral state on a

134 have suggested that BCG vaccination can have nonspecific effects, reducing general nontuberculosis mo

135 ay-based sensitivity analysis to control for nonspecific effects.

136 before 9 months of age might have beneficial nonspecific effects.

137 ostatic calculations show that, as expected, nonspecific electrostatic interactions between BtPI-PLC

138 specific interactions with HNE and overcome nonspecific electrostatic interactions that can otherwis

139 of the nucleoprotein (N), thereby preventing nonspecific encapsidation of cellular RNAs.

140 onic pain can also induce a generalized site-nonspecific enhancement in the aversive response to noci

141 icle or various concentrations of estradiol (nonspecific ER agonist) or genistein (ERbeta-selective a

142 RT-qPCR verified model specific and nonspecific expression of 23 immune-associated genes.

143 ing with this system is not practical due to nonspecific extraction of both cell-free and cell-associ

144 generically influences circadian clocks in a nonspecific fashion: The regular, discrete jumps in gene

145 In this review, nonspecific findings of congenital infections initially

146 uorescence imaging directions: one that uses nonspecific fluorescence dyes, addressing tissue perfusi

147 in Chagas heart disease (ChHD), but most are nonspecific for T. cruzi infection.

148 hus, standard-of-care treatment is currently nonspecific for this lymphoma entity.

149 coatings that combine the ability to resist nonspecific fouling from complex media with high bioreco

150 ng that antibiotics did not serve as useful, nonspecific growth promoters for humans.

151 >1000-fold compared to similar levels of the nonspecific H2 S donor, GYY4137 and also improved syngra

152 Nonspecific halogenation that leads to trihaloacetyl for

153 tive) was 5.0 +/- 1.3 %ID/g and a control of nonspecific human IgG (89)Zr-DFO-IgG in U87MG tumors was

154 and any remaining tatCN21 effects have to be nonspecific (i.e. mediated by other targets).

155 We observed that some CCD-positive sera show nonspecific IgE binding even with CCD-free recombinant a

156 Bone marrow T cell activation is nonspecific, IL-12-dependent, and induces innate memory

157 s a need for fewer cells and reduced risk of nonspecific immune suppression.

158 We detect a transient period of nonspecific immunity between infections lasting 19 (17-2

159 n used as a carrier/adjuvant in vaccines and nonspecific immunostimulant in cancer.

160 gic airway inflammation without the need for nonspecific immunosuppression in animals with establishe

161 To diminish the probable nonspecific impedance changes and decrease time of measu

162 -reactive, and antibody detection of ZIKV is nonspecific in populations previously exposed to any of

163 By comparing the specific DNA with the nonspecific in unbound, intermediate, and associated sta

164 Nonspecific inactivation of gammaretroviruses by serum f

165 ctivity in putative pyramidal neurons due to nonspecific increases in activity.

166 vir (a neuraminidase inhibitor) and T-705 (a nonspecific inhibitor of viral polymerases) could extend

167 Irreversible inhibitors developed from the nonspecific inhibitor tranylcypromine have entered clini

168 tural killer (NK) cells have been defined by nonspecific innate killing of virus-infected and tumor c

169 nstraint for binding epitopes and leading to nonspecific interaction with mammalian cell membranes.

170 hat may be recruited to the granules through nonspecific interactions are also considered in the mode

171 occurring at intermediate concentrations and nonspecific interactions between partially unfolded prot

172 mpared to optically resolvable sites so that nonspecific interactions compete with a much greater num

173 This method is based on the nonspecific interactions of multiple unstable lanthanide

174 is simple ready-to-go method is based on the nonspecific interactions of multiple unstable lanthanide

175 form DA-TAT-PECL is developed to inhibit the nonspecific interactions of TAT in the bloodstream.

176 Importantly, nonspecific interactions were detected even for purified

177 pectively, suggesting electrostatic and also nonspecific interactions with EfOM.

178 obes should be highly cell permeable without nonspecific interactions with other cellular components

179 l, a protein resistant layer, which prevents nonspecific interactions with proteins and a layer conta

180 ues suggests that this toxicity results from nonspecific interactions with the cell membrane.

181 r binding partners or alternatively decrease nonspecific interactions.

182 ervation of a protein in which transient and nonspecific intermolecular hydrophobic contacts are form

183 (18)F-FDG PET often exhibits nonspecific internalization and low specificity and sens

184 autoimmune conditions (11.5%), or fibrosing nonspecific interstitial pneumonia (7.2%).

185 ge, 72 years [range, 38-93 years]), 244 with nonspecific interstitial pneumonia (men, 79; women, 165;

186 onitis (P < .001), and 27 of 244 (11.1%) had nonspecific interstitial pneumonia (P < .001).

187 , heart failure patients with narrow QRS and nonspecific intraventricular conduction delay (NICD) dis

188 , mediates simultaneous lipid scrambling and nonspecific ion transport.

189 mitters, tumors will receive almost entirely nonspecific irradiation.

190 Nonspecific ischemic alterations were detected by electr

191 o 30% of deaths in trials, its definition is nonspecific; it is unclear what proportion represents ar

192 tes must destroy target cells while avoiding nonspecific killing of surrounding healthy cells.

193 y NOP deletion, excluding the possibility of nonspecific learning deficits or generalized disruption

194 KANSL2 is an integral subunit of the nonspecific lethal (NSL) chromatin-modifying complex tha

195 The innovative use of a nonspecific ligand allows a widespread "net" for cancer

196 for each ligand indicate larger variance for nonspecific ligand-receptor interactions.

197 diffusive binding by ETV6 proceeds through a nonspecific-like intermediate, 2) intersegmental jumping

198 mainly to rely upon cross-reactivity between nonspecific lipid transfer proteins or thaumatin-like pr

199 Nonspecific lipid transfer proteins reversibly bind diff

200 ng to maintain conformation (e.g., albumins, nonspecific lipid transfer proteins, saposins, nematode

201 All patients presented with nonspecific manifestations, including fever (96%), malai

202 ive experience in a generalized anatomically nonspecific manner.

203 Nonspecific measures of brain activity have implicated t

204 ll impaired by ZIP application, suggesting a nonspecific mechanism of action.

205 the first systematic in vivo measurements of nonspecific metabolite permeability across the peroxisom

206 oncentrations of 6 common dialkylphosphates, nonspecific metabolites of organophosphate pesticides, w

207 Nonspecific metal adducts can affect the extent of colli

208 nd the analysis of bacterial biofilms, where nonspecific methods based on physical and chemical chara

209 nti) giving rise to a relatively plastic and nonspecific mode of binding, in stark contrast to eIF4E.

210 The relatively "nonspecific" mode of action and resistance mechanisms of

211 ty of FtsZ during its life cycle acting as a nonspecific modulating factor of cell function.

212 % in the presence of various interference of nonspecific molecules.

213 nt ID per gram, 0.42 +/- 0.051; P = .20) and nonspecific muscle uptake (percent ID per gram, 0.41 +/-

214 However, because of higher nonspecific muscle uptake in female mice, tumor-to-muscl

215 It is most often nonspecific, musculoskeletal, and self-limiting.

216 Because of the nonspecific nature of FDG uptake by any cell (upregulate

217 pproach that accounts for GC effects on both nonspecific noise and signal induced by the binding site

218 intact four-chain Ab heteromultimer reveals nonspecific, non-enzymatic reactions (glycation), which

219 hondrial DNA repair; the enzyme belongs to a nonspecific nuclease family that includes the apoptotic

220 chemical conjunctivitis, or a combination of nonspecific ocular chemical burn and chemical poisoning

221 nce serotypes 33A and 33F exhibit comparable nonspecific opsonophagocytic killing, biofilm production

222 increased cell wall accessibility, increased nonspecific opsonophagocytic killing, enhanced biofilm f

223 Further study of nonspecific OPV effects before global cessation is suppo

224 nt tomographic imaging techniques are either nonspecific or lack the necessary resolution to quantify

225 In surface-based biosensors, the nonspecific or undesired adsorption of the probe is an i

226 nclude graft quality, inflammation (whether "nonspecific" or related to a specific diagnosis), infect

227 uated for each detected lesion, and tumor-to-nonspecific organ ratios were calculated.

228 MCD apparently evolved toward preventing the nonspecific oxidation of succinyl-CoA, which is a close

229 te 2 protein (MDM2) and wild-type p53 over a nonspecific p53 mutant in a real-time microfluidic analy

230 specificity for stiffness, instability, and nonspecific pain.

231 We then employed a nonspecific PCR-based library preparation method for seq

232 rejection, however, requires treatment with nonspecific pharmacologic immunosuppressants that carry

233 To understand how these nonspecific physical signals influence motility, we look

234 e a local noise level of 20%, the model with nonspecific plasticity outperforms the standard, specifi

235 The nonspecific plasticity these neuromodulators may induce

236 ing is rate-limited by dissociation from the nonspecific polymer, and 3) dissociation of the specific

237 nges in bilayer properties may contribute to nonspecific, promiscuous changes in membrane protein and

238 ant cholera toxin subunit B (CTB) may confer nonspecific protection against respiratory infections.

239 ue substrates with the toxic consequences of nonspecific protein destruction, principles found in one

240 e ATP hydrolysis by inactive proteasomes and nonspecific proteolysis and enhance proteasomal specific

241 e components of plant defense are relatively nonspecific, providing multiple disease resistance (MDR)

242 Our results suggest that OPV may cause nonspecific reductions in mortality, as has been studied

243 dence on temperature and is achieved through nonspecific regulation, and (iv) how thermal instability

244 con) cells and asthma by activating allergen-nonspecific regulatory T (Treg) cells to create a TH2-po

245 , with predominantly renal clearance and low nonspecific retention in the liver and spleen at 24 h af

246 Fluorescein angiography (FA) showed nonspecific retinal inflammation, and an electroretinogr

247 Nonspecific retinal whitening occurred in 3 (35%) and 5

248 nonpurified alphavbeta3-Fc integrin, whereby nonspecific rupture events were corrected by using a new

249 ve site, resulting in highly hydrophilic and nonspecific scaffolds.

250 olor saturation by mitigating the effects of nonspecific scattering that is present in most samples d

251 is important for the progression of AAG from nonspecific searching to specific-recognition complexes.

252 2 (54.4% [95% CI, 44.7%-64.0%]) extrapolated nonspecific secondary diagnoses to infer in-hospital eve

253 howed that (18)F-4FMFES PET achieves a lower nonspecific signal and better tumor contrast than (18)F-

254 rom true target-binding events while keeping nonspecific signals at a minimum level.

255 architecture that elicits marginal levels of nonspecific signals in cells.

256 ons (n = 387; 18%), injuries (n = 289; 13%), nonspecific signs and symptoms, e.g., fever (n = 281; 13

257 celerated when Na(+) binds to an allosteric, nonspecific site, leading to a 2-fold increase in ATPase

258 allergic response to attacks in humans from nonspecific skin-penetrating cercariae.

259 In order to mitigate the ambiguity due to nonspecific sources of contrast such as off-target bindi

260 must be large enough to prevent frequent and nonspecific spontaneous fusion events, yet must be low e

261 and cytokine responses to HIV-specific and -nonspecific stimuli were assessed with and without PD-1

262 Psychotherapy (CBASP) compared with that of nonspecific supportive psychotherapy (SP).

263 more widely distributed across visual space, nonspecific suppression was found more often in the peri

264 Additionally, nonspecific surface adhesion hinders studies of alpha-he

265 the Zika virus (ZIKV) is usually mild, with nonspecific symptoms and most often asymptomatic.

266 Denmark to investigate patients with serious nonspecific symptoms and signs of cancer (NSSC), who are

267 e-phone base stations and the development of nonspecific symptoms and sleep disturbances over time.

268 e diagnosis of PVS is challenging because of nonspecific symptoms and the need for dedicated pulmonar

269 The rest presented with the mild and nonspecific symptoms of cough, coryza, and/or tachypnea.

270 he preceding 2 weeks, presented with similar nonspecific symptoms of lethargy, fatigue, and nausea.

271 Approximately 90% had nonspecific symptoms potentially compatible with AF, suc

272 -infected individuals display no symptoms or nonspecific symptoms similar to other viral infections.

273 AMS may progress from nonspecific symptoms to life-threatening high-altitude c

274 ed exposure (0 = not at all; 6 = very much), nonspecific symptoms, and sleep disturbances were assess

275 Because patients with CS often present with nonspecific symptoms, normal electrocardiography, and pr

276 tein-Barr virus (EBV) are asymptomatic, have nonspecific symptoms, or have self-limiting infectious m

277 able and reveal that a logic based on local, nonspecific synergistic effects, largely among pioneer T

278 effusion with the signal intensity of fluid (nonspecific synovitis).

279 ivery and release capabilities and minimized nonspecific systemic spread of drugs, remarkably enhanci

280 ment, but is associated with toxicity due to nonspecific T-cell activation.

281 Given that eczema is a nonspecific term that describes the morphological appear

282 st that the uptake mechanism could be rather nonspecific The assay promises to be a powerful tool for

283 While generally nonspecific, the clinical presentation corresponding to

284 have evolved over the decades from broad and nonspecific therapies to those that are now more targete

285 hotherapy was moderately more effective than nonspecific therapy in outpatients with early-onset chro

286 Further intensification of nonspecific therapy is unlikely to offer additional bene

287 Moreover, nonspecific thrombin inhibition has been shown to decrea

288 are used, differences in biodistribution and nonspecific tissue uptake can adversely affect quantitat

289 The SUVmean of nonspecific tissues and the SUVmax of the tumor were eva

290 Lower uptake was consistently observed in nonspecific tissues for (18)F-4FMFES, notably a 4-fold d

291 Unlike crystalline MOF, amorphous CP is nonspecific to metal cation species, therefore its compo

292 r fleas, protozoan, and bacteria) with known nonspecific toxicity to chemical substances.

293 The most common complication observed was nonspecific transient abdominal pain and transient hypot

294 cycle and growth rates, and the existence of nonspecific, transient interactions between ribosomes an

295 s were cocultured with SEA-reactive allergen-nonspecific Treg or CD4 Tcon cells in the presence of OV

296 its with antibiotic-inappropriate diagnoses (nonspecific upper respiratory tract infections, acute br

297 This defect in immune regulation led to a nonspecific upregulation of effector proinflammatory pat

298 complete targeting to the tumor site without nonspecific uptake by the immune system.

299 urrent prostate cancer, although issues with nonspecific uptake limit the potential role of (18)F-flu

300 ring WNV infection, Ccr7 is a gatekeeper for nonspecific viral transference to the brain.IMPORTANCE I