ライフサイエンスコーパス: nonstructural protein

1 ar the C terminus of NS5A, a multifunctional nonstructural protein.

2 ied as a novel inducer of apoptosis, as were nonstructural proteins.

3 ural DENV infection and were more focused on nonstructural proteins.

4 o be inhibited through interference of viral nonstructural proteins.

5 with live virus to expression of individual nonstructural proteins.

6 s abundantly present in virions and shorter, nonstructural proteins.

7 genome that encodes four structural and two nonstructural proteins.

8 The T3SS consists of structural and nonstructural proteins.

9 arkers in the 3D polymerase (3D(pol)) and 3B nonstructural proteins.

10 tionally cleaved into at least 13 functional nonstructural proteins.

11 anscripts encoding capsid proteins and small nonstructural proteins.

12 1b region and provide alternative sources of nonstructural proteins.

13 a, virus shedding or antibodies against FMDV nonstructural proteins.

14 The nonstructural protein 1 (A/NS1) of influenza A viruses (

15 e of an RDT that detects dengue virus (DENV) nonstructural protein 1 (NS1) and anti-DENV IgM during s

16 y spliced to express two viral proteins, the nonstructural protein 1 (NS1) and the nuclear export pro

17 rbent assays (ELISAs), for detection of DENV nonstructural protein 1 (NS1) antigen and anti-DENV IgM.

18 ctivity, IgG and IgA antibodies against ZIKV nonstructural protein 1 (NS1) antigen were specific to Z

19 molecular mimicry in which Abs against DENV nonstructural protein 1 (NS1) cross-react with human end

20 The flavivirus nonstructural protein 1 (NS1) functions in genome replic

21 DENV nonstructural protein 1 (NS1) has long been considered a

22 Antibodies directed against the flavivirus nonstructural protein 1 (NS1) have been proposed as sero

23 The influenza virus nonstructural protein 1 (NS1) inhibits innate immunity b

24 The Flavivirus nonstructural protein 1 (NS1) is a conserved, membrane-a

25 Human respiratory syncytial virus (HRSV) nonstructural protein 1 (NS1) is a good example of this.

26 Flavivirus nonstructural protein 1 (NS1) is a unique secreted nonst

27 Influenza A virus (IAV) nonstructural protein 1 (NS1) is a virulence factor esse

28 The viral nonstructural protein 1 (NS1) is essential in this proce

29 The multifunctional nonstructural protein 1 (NS1) is the main viral factor c

30 Interestingly, nonstructural protein 1 (NS1) of RSV promoted proteasome

31 In this study, we demonstrated that the nonstructural protein 1 (NS1) of WNV antagonizes IFN-bet

32 This study demonstrated that the nonstructural protein 1 (NS1) of WNV antagonizes the ind

33 ZIKV nonstructural protein 1 (NS1) plays an essential role in

34 Nonstructural protein 1 (NS1) proteins from avian influe

35 notransferase (AST) level, positivity in the nonstructural protein 1 (NS1) rapid test, and viremia ma

36 Parvoviruses encode a large nonstructural protein 1 (NS1) that is essential for repl

37 rbent assays (ELISAs) based on ZIKV and DENV nonstructural protein 1 (NS1) were established to test a

38 Antibodies to nonstructural protein 1 (NS1) were largely ZIKV-specific

39 of epitopes in the C-terminal region of DENV nonstructural protein 1 (NS1) which are cross-reactive w

40 2), PB1, PB1-F2, Polymerase Acidic-X (PA-X), Nonstructural Protein 1 (NS1), and Nuclear Export Protei

41 uenza virus encodes both the multifunctional nonstructural protein 1 (NS1), essential for innate immu

42 sing a live influenza virus with a truncated nonstructural protein 1 (NS1), we are able to stimulate

43 We previously generated a ZIKV nonstructural protein 1 (NS1)-specific human monoclonal

44 tudy, we applied a previously developed anti-nonstructural protein 1 (NS1)-specific MAC-ELISA (NS1-MA

45 antibodies for rapid detection of the dengue nonstructural protein 1 (NS1).

46 ied M segment and the open reading frames of nonstructural protein 1 (NS1)/nuclear export protein (NE

47 toantibodies elicited by dengue virus (DENV) nonstructural protein 1 (NS1; anti-NS1 Igs) induce plasm

48 cute respiratory syndrome (SARS) coronavirus nonstructural protein 1 (nsp1) binds to the 40S ribosoma

49 viously, we reported that replacement of the nonstructural protein 1 (nsP1) gene of the mouse-virulen

50 The nonstructural protein 1 (nsp1) of CoVs is one such prote

51 Similar to the nonstructural protein 1 (nsp1) of SARS-CoV that inhibits

52 us studies, RV genes encoding VP3, VP4, VP7, nonstructural protein 1 (NSP1), and NSP4 have all been i

53 oV genome: the papain-like protease (PLPro), nonstructural protein 1 (nsp1), ORF6, and ORF7a.

54 n approximately 200 nt downstream within the nonstructural protein 1 (Nsp1)-coding region.

55 (SARS-CoV), establish host shutoff via their nonstructural protein 1 (nsp1).

56 magnitude and kinetics of plasma viremia and nonstructural protein 1 (sNS1) levels in sequential samp

57 c 5' untranslated region and 186 nt from the nonstructural protein 1 [nsp1]-coding region) not found

58 during different stages of infection (viral nonstructural protein 1 and immunoglobulin M) has greatl

59 alized with dengue, confirmed through dengue nonstructural protein 1 and/or immunoglobulin M detectio

60 odes were determined to be VCD by means of a nonstructural protein 1 antigen immunoassay and reverse-

61 virus autoregulation by targeting the virus nonstructural protein 1 gene.

62 ns is an inherent aspect of influenza HA and nonstructural protein 1 proteins; further, this may expl

63 er enrollment to negative viremia and dengue nonstructural protein 1 status.

64 Moreover, rotavirus NSP1 (nonstructural protein 1) employs a pLxIS motif to target

65 dance proteins like the matrix protein 2 and nonstructural protein 1, with a similar impurity level o

66 hemagglutinin head and the immune-modulatory nonstructural protein 1.

67 Our data are consistent with RSV nonstructural proteins 1 and/or 2 perturbing the Jak-STA

68 Here, we report that flavivirus nonstructural protein-1 (NS1), which is abundantly secre

69 CoV nonstructural protein 14 (nsp14) encodes 3'-to-5' exorib

70 The coronavirus (CoV) nonstructural protein 14 (nsp14) is a multifunctional pr

71 in encoding a 3'-->5' exoribonuclease within nonstructural protein 14 (nsp14-ExoN) that is required f

72 CoVs encode a proofreading exonuclease in nonstructural protein 14 (nsp14-ExoN), which confers a g

73 Here we report that coronavirus nonstructural protein 15 (nsp15), an endoribonuclease, i

74 he region of the replicase gene encoding the nonstructural protein 15 subunit of the viral replicase-

75 ctive and respiratory syndrome virus (PRRSV) nonstructural protein 1beta (nsp1beta) is a multifunctio

76 rine coronavirus mouse hepatitis virus (MHV) nonstructural protein 2 (ns2) is a 2',5'-phosphodiestera

77 ne coronavirus (mouse hepatitis virus [MHV]) nonstructural protein 2 (ns2) is a 2',5'-phosphodiestera

78 The RSV nonstructural protein 2 (NS2) is a multifunctional prote

79 We report the identification of nonstructural protein 2 (nsp2) as a novel structural com

80 PRRSV nonstructural protein 2 (nsp2) was previously identified

81 residues 62-70; K(b)NS2(114), and influenza nonstructural protein 2 amino acid residues 114-121), de

82 in of murine hepatitis virus as fusions with nonstructural protein 2 or 3 and whether such reporters

83 t protein and firefly luciferase with either nonstructural protein 2 or 3 is tolerated and that these

84 Flavivirus nonstructural protein 2B (NS2B) is a transmembrane prote

85 n an interaction between capsid proteins and nonstructural protein 2C(ATPase) In particular, residue

86 of capsid proteins with the multifunctional nonstructural protein 2C(ATPase) In this study, we have

87 fficient expression of a transframe protein [nonstructural protein 2TF (nsp2TF)] of porcine reproduct

88 ify groups of coevolving residues within HCV nonstructural protein 3 (NS3) by analyzing diverse seque

89 turally occurring polymorphism, Q80K, in the nonstructural protein 3 (NS3) gene encoding the viral pr

90 The viral nonstructural protein 3 (NS3) plays a key role in mediat

91 The capsid protein followed by nonstructural protein 3 (NS3), NS2A, and NS5 were the mo

92 licase contained in the C-terminal domain of nonstructural protein 3 (NS3).

93 V replication complex is a helicase known as nonstructural protein 3 (NS3).

94 was subsequently shown to recognize the HCV nonstructural protein 3 (NS3):1406-1415 epitope with hig

95 nfection, the C-terminal domain of the viral nonstructural protein 3 (nsP3) forms a complex with Ras-

96 sion of the reporter protein in frame within nonstructural protein 3 (nsP3) or insertion of the repor

97 One determinant of alphavirus virulence is nonstructural protein 3 (nsP3) that contains a highly co

98 his phenotypic difference is associated with nonstructural protein 3 (nsP3).

99 ase (ADRP) activity within the N terminus of nonstructural protein 3 (nsp3).

100 f the viral replicase-transcriptase complex, nonstructural protein 3 (nsp3).

101 ssential for viral replication and assembly (nonstructural protein 3 [NS3]).

102 Based upon nonstructural protein 3 sequence analysis, no compartmen

103 nent of the replicase-transcriptase complex, nonstructural protein 3, at a critical early stage of in

104 to strengthen interaction between RCHY1 and nonstructural protein 3, leading to a further increase i

105 ithin the Ubl domain, residues 785 to 787 of nonstructural protein 3, which negatively affect proteas

106 -like protease is encoded next to SUD within nonstructural protein 3.

107 5A inhibitor velpatasvir with or without the nonstructural protein 3/4A protease inhibitor voxilaprev

108 09) is a macrocyclic hepatitis C virus (HCV) nonstructural protein 3/4A protease inhibitor.

109 rect-acting antiviral agents that target the nonstructural protein 3/4A protease of hepatitis C virus

110 an inhibitor of the hepatitis C virus (HCV) nonstructural protein 3/4A protease; MK-5172 is taken on

111 variation in the hepatitis C virus protease nonstructural protein 3/4A sequences might affect suscep

112 First, we confirmed the presence of HCV nonstructural proteins 3, 4b, and 5a besides HCV core an

113 Nonstructural protein 3A of foot-and-mouth disease virus

114 ressed the protease in context with flanking nonstructural protein 4 (nsp4) and the amino-terminal po

115 Rotavirus nonstructural protein 4 (NSP4) induces dramatic changes

116 Rotavirus (RV) nonstructural protein 4 (NSP4) is a virulence factor tha

117 Rotavirus nonstructural protein 4 (NSP4) is an endoplasmic reticul

118 Nonstructural protein 4 (NSP4) viroporin activity is cri

119 irus as a pathogen that encodes a viroporin, nonstructural protein 4, which releases endoplasmic reti

120 PgV-2 E2 glycoprotein or bacterium-expressed nonstructural protein 4AB (NS4AB) in detecting past or p

121 Dengue virus nonstructural protein 4B (NS4B) is a membrane protein co

122 n of proline at amino acid 219 (P219) of the nonstructural protein 4B (NS4B) with serine, threonine o

123 cation via direct interaction with the viral nonstructural protein 4B (NS4B).

124 The large flavivirus nonstructural protein 5 (NS5) (105 kDa) has RNA methyltr

125 Nonstructural protein 5 (NS5) contains a methyltransfera

126 Dengue virus (DENV) nonstructural protein 5 (NS5) is composed of two globula

127 One RRV construct expressed nonstructural protein 5 (NS5), while a second recombinan

128 Further study showed that nonstructural protein 5 (nsp5) of PRRSV induced the STAT

129 unds inhibiting the interaction between DENV nonstructural protein 5 and host nuclear transport prote

130 Nonstructural protein 5 is essential for capping and rep

131 riments showed that ZIKV RNA replication and nonstructural protein 5 translation were reduced below t

132 etween PI(4,5)P2 and hepatitis C virus (HCV) nonstructural protein 5A (NS5A) and effects on the viral

133 Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) and its interaction with

134 ptosis, and that the hepatitis C virus (HCV) nonstructural protein 5A (NS5A) could inhibit Kv2.1-medi

135 ary structure and long-range interactions in nonstructural protein 5A (NS5A) from hepatitis C virus (

136 tudy to assess whether adding daclatasvir, a nonstructural protein 5A (NS5A) inhibitor that is active

137 een treated with an HCV regimen containing a nonstructural protein 5A (NS5A) inhibitor; and * genotyp

138 s recommend that patients who have failed on nonstructural protein 5A (NS5A) inhibitors should be ret

139 Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) is a phosphoprotein that

140 Nonstructural protein 5A (NS5A) is essential for hepatit

141 cation, and mounting evidence indicates that nonstructural protein 5A (NS5A) is the major target of C

142 Nonstructural protein 5A (NS5A) of hepatitis C virus (HC

143 Nonstructural protein 5A (NS5A) of hepatitis C virus (HC

144 ring polymorphisms on the potency of the HCV nonstructural protein 5A (NS5A) replication complex inhi

145 Direct-acting antivirals that target nonstructural protein 5A (NS5A), such as daclatasvir, ha

146 All-oral therapy with daclatasvir (nonstructural protein 5A [NS5A] inhibitor), asunaprevir

147 ral protein 5B inhibitor sofosbuvir plus the nonstructural protein 5A inhibitor velpatasvir with or w

148 ombination of daclatasvir (DCV; pangenotypic nonstructural protein 5A inhibitor) and sofosbuvir (SOF;

149 containing regimens, particularly those with nonstructural protein 5A inhibitors, are limited and rem

150 Nonstructural protein 5B (NS5B) is essential for hepatit

151 rug that targets the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase and inhibits

152 gimens that included the nucleotide analogue nonstructural protein 5B inhibitor sofosbuvir plus the n

153 A inhibitor) and sofosbuvir (SOF; nucleotide nonstructural protein 5B inhibitor) for 12 weeks previou

154 all HCV DAAs and, in particular, not all HCV nonstructural protein 5B inhibitors may exhibit this car

155 vir, an oral nucleotide inhibitor of the HCV nonstructural protein 5B RNA-dependent RNA polymerase en

156 tis C viral genome is catalyzed by the NS5B (nonstructural protein 5B) RNA-dependent RNA polymerase,

157 Nonstructural protein 9 (Nsp9) is the RNA-dependent RNA

158 rsal of the Golgi structure, and these three nonstructural proteins also inhibited protein secretion.

159 In HCV-infected cells, various HCV nonstructural proteins also interact or colocalize with

160 First, we expressed each individual nonstructural protein and examined their cellular locali

161 y important TM dimer interface within an HCV nonstructural protein and reveal a fundamental role of t

162 nonstructural proteins and/or between viral nonstructural proteins and cell proteins are involved in

163 possibility that interactions between viral nonstructural proteins and/or between viral nonstructura

164 Furthermore, these drugs target HCV nonstructural proteins, and with selective pressure, the

165 Viral nonstructural proteins are often important for virus rep

166 HCV nonstructural proteins are shown to colocalize with DDX3

167 proteomics led to the identification of HCV nonstructural proteins as well as proteins involved in m

168 Here we show that the point mutations in the nonstructural protein-coding region (P2, P3) that accumu

169 Our data indicate that both structural and nonstructural proteins contribute to MHV liver pathogene

170 in of murine hepatitis virus as fusions with nonstructural proteins could define the expression and t

171 ectural network consisting of structural and nonstructural proteins, creating strength and plasticity

172 Using monoclonal antibody fragments against nonstructural protein dengue NS1, an early biomarker for

173 tly, resulting in infection and synthesis of nonstructural proteins despite undetectable systemic vir

174 y of immunodominance among structural versus nonstructural proteins differs as a function of the infe

175 h genetic vaccines encoding the HCV NS3-NS5b nonstructural proteins during DAA treatment resulted in

176 studies have suggested that multifunctional nonstructural proteins encoded by flaviviruses antagoniz

177 ell populations specific for variants of the nonstructural protein epitope NS3133 that characterize t

178 e compared to the African lineage, mainly in nonstructural proteins, especially protein NS4B.

179 e, little information is available about the nonstructural proteins essential for viral replication,

180 ovides a unique example of how a small viral nonstructural protein facilitates the multifaceted regul

181 e formation is linked to expression of viral nonstructural proteins, FMDV induced autophagosomes very

182 the genetic background of codon-deoptimized nonstructural protein genes and a deleted small hydropho

183 We hypothesized that the coding regions of nonstructural proteins harbor enhancer and essential cis

184 (HCV) using T-cell-based vaccines targeting nonstructural proteins has not resulted in the same leve

185 an be replicated by expression of individual nonstructural proteins; however the situation with diffe

186 DENV T cell epitopes are found primarily in nonstructural proteins.IMPORTANCE The issue of potential

187 understood, particularly the function of its nonstructural proteins in RNA replication and modificati

188 eus and is essential for expression of viral nonstructural proteins independent of RNA-activated prot

189 sid proteins (53.7% coverage), but none from nonstructural proteins, indicating capsids are packaged

190 Many of the nonstructural proteins involved in replication possess m

191 Among them, we proved that one nonstructural protein is critical to the replication of

192 Viral tegument, envelope, and some nonstructural proteins localize to the cVAC, and cytoske

193 The MRV nonstructural protein muNS comprises the structural matr

194 researchers have focused on visualizing the nonstructural protein muNS, which forms the VF matrix.

195 A viral nonstructural protein, muNS, forms large inclusion-like

196 viruses as well as viruses with only p7 and nonstructural protein mutations.

197 Further analysis identified that the small nonstructural protein NP1 is required for HBoV1 DNA repl

198 In this study, we demonstrated that the nonstructural protein NP1 is required for the expression

199 cross-reactive Abs, which can recognize DENV nonstructural protein (NS) 1, have been found in dengue

200 in cell culture identified a mutation in HCV nonstructural protein (NS) 4B conferring partial resista

201 were stratified by their cirrhosis and past nonstructural protein (NS) 5A inhibitor exposure.

202 ved HLA-A2-restricted CTL epitope within the nonstructural protein (NS) 5A viral protein and comparin

203 Here, we show that the HCV protein, nonstructural protein (NS) 5B, directly binds to the tum

204 ing plasmid, pHBoV1NSCap, that harbors HBoV1 nonstructural protein (NS) and capsid protein (Cap) gene

205 y and safety of a combination regimen of the nonstructural protein (NS)5A inhibitor ledipasvir (LDV),

206 CypA binds to HCV's nonstructural protein (NS)5A to promote replication of v

207 Nonstructural protein (NS)5B inhibitors sofosbuvir, meri

208 Tegobuvir (GS-9190), a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor, and G

209 of differentiation (CD)8(+) T-cell epitope, nonstructural protein (NS)5B(2841-2849) (ARMILMTHF), has

210 addition to NP1, MVC encodes five additional nonstructural proteins (NS) that share an initiation cod

211 ssociated substitutions (RASs) in HCV genes (nonstructural protein [NS]3, NS5A, NS5B) targeted by DAA

212 ek regimen of daclatasvir (DCV; pangenotypic nonstructural protein [NS]5A inhibitor) plus sofosbuvir

213 h B19V infection and expression of the large nonstructural protein NS1 arrested EPCs at a cell cycle

214 (SUMO) and influenza A virus identified the nonstructural protein NS1 as the first known SUMO target

215 The large viral nonstructural protein NS1 is sufficient to induce the DD

216 mbined the codon deoptimization of genes for nonstructural proteins NS1 and NS2 (dNS), deletion of th

217 SR regulates the expression of HBoV1-encoded nonstructural proteins NS1, NS2, NS3, and NP1 but not NS

218 nor sites, namely, A1' and D1', in the large nonstructural protein (NS1)-encoding region of the HBoV1

219 However, we found that the other four nonstructural proteins (NS1 to -4) are not required for

220 NP1 and other viral nonstructural proteins (NS1 to NS4) colocalized within t

221 B (GBV-B) chimeric virus carrying the major nonstructural proteins NS2 to NS4A (HCV NS2 to -4A chime

222 e that contains the cofactor region from the nonstructural protein NS2B and the protease domain from

223 uorescent mCherry protein fused to the viral nonstructural protein NS3 (BTV-1/NS3mCherry) was generat

224 HCV nonstructural protein NS3/4A interacts with CHK2 and dow

225 d transiently inhibits expression of the HCV nonstructural proteins NS3 and NS5A as well as HCV struc

226 eproducibly detected low levels of the viral nonstructural protein, NS3.

227 In this study, we show that the BTV nonstructural protein NS4 favors viral replication in sh

228 this piperazinone chemotype targets the HCV nonstructural protein NS4B.

229 Here, we report that the nonstructural protein NS5 of ZIKV and other flaviviruses

230 otent viral inhibitor of this pathway is the nonstructural protein NS5.

231 ntified a novel cellular target of the viral nonstructural protein NS5A and demonstrated its role in

232 show here that phosphorylation of the viral nonstructural protein NS5A at serine residues is importa

233 es to elucidate host factors involved in HCV nonstructural protein NS5A function and found that MOBKL

234 helical (AH) domain of the hepatitis C virus nonstructural protein NS5A, anchored at the cytoplasmic

235 host response to HCV infection is the viral nonstructural protein NS5A, which, in addition to its ro

236 hipathic peptide resembling a segment of the nonstructural protein (NS5A) of the hepatitis C virus.

237 l structural glycoproteins, Gn and Gc, and a nonstructural protein, NSm.

238 genic, involving at least one gene from both nonstructural protein (nsP) and structural protein (sP)

239 by a replicase-transcriptase composed of 16 nonstructural protein (nsp) subunits.

240 Rotavirus nonstructural protein NSP1 can inhibit expression of int

241 drome coronavirus is composed of at least 16 nonstructural proteins (nsp1-16) encoded by the ORF-1a/1

242 viral replication machinery consists of four nonstructural proteins (nsP1-4) produced as a single pol

243 Rotavirus nonstructural protein NSP2, a functional octamer, is cri

244 the capsid-specific helix I but also in the nonstructural protein nsP2.

245 One of these nonstructural proteins, nsP3, contains a hypervariable d

246 The nonstructural protein NSP4 of rotavirus is a multifuncti

247 d complex networks of interactions involving nonstructural proteins (NSPs) 2, 5, and 6 and structural

248 y complex networks of interactions involving nonstructural proteins (NSPs) and structural proteins (V

249 RNA synthesis is mediated by the nonstructural proteins (NSPs) P200 and its cleavage prod

250 Three viral nonstructural proteins (nsps), nsp3, nsp4, and nsp6, are

251 Coronaviruses encode 16 nonstructural proteins (nsps), three of which, nsp3, nsp

252 that is unusually complex and composed of 16 nonstructural proteins (nsps).

253 We generated viruses lacking the nonstructural protein NSs and show that UUKV NSs is a we

254 ments through interactions between the viral nonstructural protein NSs and the host general transcrip

255 The nonstructural protein NSs is a major virulence factor kn

256 In this study, we report that the nonstructural protein NSs of the newly described severe

257 ed two recombinant viruses, one in which the nonstructural protein NSs open reading frame was deleted

258 Viral nonstructural protein NSs was inhibitory to the inductio

259 resulting from deletions or mutations in the nonstructural protein NSs.

260 glycoproteins Gn and Gc, as well as putative nonstructural proteins NSs and NSm.

261 iruses, it has been well documented that the nonstructural protein (NSs) enables the virus to counter

262 s of the family Bunyaviridae, TOSV encodes a nonstructural protein (NSs) in its small RNA segment.

263 V (rHB29NSsKO) that cannot express the viral nonstructural protein (NSs) upon infection of cells in c

264 d no amino acid changes were observed in the nonstructural proteins (NSs and NSm), the nucleocapsid p

265 express the nucleocapsid protein, N, and the nonstructural protein, NSs.

266 The HCV genome coding for nonstructural proteins (nucleotide positions 3872 to 909

267 In this study, we show that a nonstructural protein of BTV (NS4) is critical to counte

268 The NSm nonstructural protein of Rift Valley fever virus (family

269 fers nuclear trafficking capabilities to the nonstructural protein of the virus and that lysine resid

270 enetic analysis using various structural and nonstructural proteins of CKoV confirmed it as the anima

271 In this report, we identified three new nonstructural proteins of human bocavirus 1 that are exp

272 virus-based vector system that combines the nonstructural proteins of Semliki Forest virus with the

273 ne is expressed from a replicon encoding the nonstructural proteins of Semliki Forest virus.

274 nsgenes, placed either immediately after the nonstructural proteins or at the 3' end of the viral cod

275 Here, we demonstrate that the nonstructural protein p17 of ARV functions as an activat

276 The nonstructural protein p7 of classical swine fever virus

277 ning the three structural proteins and seven nonstructural proteins present in ZIKV, we found that tw

278 t the Ebola virus delta peptide, a conserved nonstructural protein produced in large quantities by in

279 Of note, unlike the large nonstructural protein (Rep78/68 or NS1) of other parvovi

280 n of RVFV lacking the gene encoding the RVFV nonstructural protein S (NSs).

281 which encodes attachment protein sigma1 and nonstructural protein sigma1s.

282 may be facilitated by association of the MRV nonstructural protein sigmaNS with the major SG effector

283 SH3-binding protein 1 (G3BP1), with the MRV nonstructural protein sigmaNS, which localizes to VFs vi

284 ve attenuated vaccines based on deletions of nonstructural proteins since single mutations in the vir

285 We also detected interactions involving nonstructural proteins, such as the DNA-binding protein

286 A virus-encoded nonstructural protein, termed NSs, is a major virulence

287 e at five nonhomologous sites, releasing six nonstructural proteins that are essential for viral repl

288 ons between distantly related structural and nonstructural proteins that are essential for virion pro

289 RNA genome, which encodes 3 structural and 7 nonstructural proteins that are expressed as a single po

290 al 20-kDa 3C-like protease (Pro, NS6) into 6 nonstructural proteins that are necessary for viral repl

291 lyprotein is required to generate the mature nonstructural proteins that form the viral replicase.

292 Like RSV, PVM also encodes two nonstructural proteins that have been implicated to supp

293 In addition to many viral nonstructural proteins, the presence of cell nuclear pro

294 share common structures in their capsid and nonstructural proteins, there is often low homology at t

295 n is restricted by the inability of the EILV nonstructural proteins to form functional replicative co

296 DNAJC14 redistributes and clusters with YFV nonstructural proteins via a transmembrane domain and a

297 ral replication by generating structural and nonstructural proteins via the cleavage of the viral pol

298 FMDV structural and nonstructural proteins were localized to follicle-associ

299 to a much less rigorous extent, in the nsp9 nonstructural protein, were primarily associated with th

300 to the immunodominance hierarchy of the DENV nonstructural proteins, with NS3, NS5, and NS1 being dom