ライフサイエンスコーパス: nontoxic

1 operon in Y. pseudotuberculosis rendered it nontoxic.

2 minal beta-amyloid fragment is monomeric and nontoxic.

3 embryos/larvae while selenate and SeNPs were nontoxic.

4 the new inhibitors are relatively stable and nontoxic.

5 , the anandamide conjugates were found to be nontoxic.

6 coccus neoformans at acidic pH, yet remained nontoxic.

7 the Orb2 protein can stabilize memory and be nontoxic.

8 complex 6 is also remarkably photostable and nontoxic.

9 stabilized low molecular weight species are nontoxic.

10 Nontoxic 18:1Delta9 was as toxic as 16:1Delta9 in a stra

11 Nontoxic 18:1Delta9 was used for phospholipid synthesis,

12 em 100 % CEES was transformed selectively to nontoxic 2-chloroethyl ethyl sulfoxide and vinyl ethyl s

13 ion through stabilization of small (dimeric) nontoxic Abeta conformers.

14 eta38 or Abeta40) and other longer peptides (nontoxic Abeta42 G33A substitution or Abeta43) did not a

15 ential applications of SPM as endogenous and nontoxic adjuvants, and as anti-inflammatory therapeutic

16 forms of polyQ proteins and direct them into nontoxic aggregates.

17 urotoxicity by promoting the accumulation of nontoxic aggregates.

18 Taken together, 10-Cl-BBQ is an effective, nontoxic AhR ligand for the intervention of immune-media

19 ducted a chemical library screen to identify nontoxic AhR ligands with anti-cancer effects and discov

20 attention has been devoted to the quest for nontoxic alternatives based on rare-earth elements.

21 The replacement of lead with nontoxic alternatives such as tin has been demonstrated

22 ldehyde products of polyamine degradation to nontoxic amino acids.

23 GSR, but the introduction of "lead-free" or "nontoxic" ammunitions makes it difficult to prevent fals

24 n favor of the formation of larger insoluble nontoxic amyloid fibrils, there by counteracting Abeta-m

25 The formation of these nontoxic and biodegradable polymer seeds led to prolonge

26 rsal Heparin Reversal Agent (UHRA), which is nontoxic and can neutralize the anticoagulant activity o

27 y gained increasing attention as potentially nontoxic and defect-tolerant solar absorbers.

28 These PA variants were individually nontoxic and demonstrated toxicity only when combined wi

29 alladium-based catalytic processes generated nontoxic and easily separable side products.

30 ical inhibition of Mnks therefore provides a nontoxic and effective strategy for cancer therapy.

31 An ST vaccine should be nontoxic and elicit an immune response that neutralizes

32 Oxoammonium salts are metal-free, nontoxic and environmentally friendly oxidants.

33 itation for crosslinking and thus provides a nontoxic and facile approach to encapsulate cells and pr

34 eurons, whereas gamma-synuclein proved to be nontoxic and had very low aggregation propensity.

35 The primary product of nZVI treatment is nontoxic and highly aggregated Fe(OH)(3), which promotes

36 Nontoxic and highly selective, VNI displays promising ph

37 tein is expressed in Escherichia coli and is nontoxic and immunogenic in mice, rabbits, and humans.

38 perational simplicity and the application of nontoxic and inexpensive CeCl3.7 H2O as precatalyst.

39 In this protocol, the nontoxic and inexpensive Fe(NO3)3.9H2O plays a dual role

40 es an experimental in vitro model system for nontoxic and low-dose coexposures of human mammary carci

41 ic activity and have hyaluronidase, which is nontoxic and nonproteolytic but promotes diffusion of to

42 lyethylene (PE) wax (Polywax) can serve as a nontoxic and nonvolatile alternative to alkane solvents

43 Indole 24 is nontoxic and showed increased potency against dynamin I

44 Besides being nontoxic and specific, desirable labelling probes should

45 ealed orally bioavailable compounds that are nontoxic and suppress parasitemia in vivo.

46 e without host-specific promoters, achieving nontoxic and tuneable gene expression in diverse Gram-po

47 Doxycycline is a relatively nontoxic and well-tolerated oral agent and should be con

48 bonate has been put forth as an inexpensive, nontoxic, and "green" potential methylating reagent.

49 hat combines fast reaction rate with stable, nontoxic, and chemoselective reagents.

50 ally manipulate, exhibit exquisite SARs, are nontoxic, and elicit improved and qualitatively differen

51 g nanocrystals described here offer a cheap, nontoxic, and environmentally friendly alternative to in

52 and on-board power supplies that are benign, nontoxic, and even biodegradable.

53 Fluoroform, CHF3, a non-ozone-depleting, nontoxic, and inexpensive gas can be used as a difluoroc

54 ontinued our effort to generate new, potent, nontoxic, and multiply effective inhibitors of the three

55 trate excellent biocompatibility, stability, nontoxic, and nonimmunogenic properties, which prove to

56 here as chromone 1, as a potent, selective, nontoxic, and nontransported inhibitor of ABCG2-mediated

57 properties using ARs is a one-step, dosable, nontoxic, and reversible method, which can be applied to

58 studied concentrations (1 nM-5 microM), are nontoxic, and showed efficacy in reducing the rate of tu

59 -loaded PLGA NPs are an effective, nonviral, nontoxic, and sustainable form of gene therapy for the r

60 tems as they are water-soluble, photostable, nontoxic, and their surface chemistry can be easily modi

61 1) was previously identified as a potent and nontoxic antiadenoviral compound.

62 Myo-Inositoltrispyrophosphate (ITPP), a nontoxic, antihypoxic compound, has recently shown signi

63 monstrated, and any protection afforded by a nontoxic antioxidant compound would be an exciting accom

64 en found to contain a high proportion of the nontoxic arsenic compound arsenobetaine (AB), but data g

65 s found (e.g., toxic inorganic arsenicals vs nontoxic arsenobetaine), and two analytical techniques,

66 on black (CB) nanoparticles were found to be nontoxic at all concentrations, while hydrophobic (annea

67 Cer-SiR is nontoxic at concentrations as high as 2 muM and does not

68 macokinetic (PK) profile than sTRAIL and was nontoxic at doses ranging from 32 fmol/kg to 3.2 pmol/kg

69 Monodisperse multifunctional and nontoxic Au@MnO Janus particles with different sizes and

70 To meet this demand, we synthesized nontoxic, azido-functionalized ceramides allowing for bi

71 nalogue of a natural substrate, a stable and nontoxic basic boron cluster system, previously used for

72 e double-perovskite structure to incorporate nontoxic Bi(3+) into the perovskite lattice in Cs2AgBiBr

73 nanoparticles and it is envisaged that these nontoxic bioactive nanostructures can be used as food pa

74 to develop a highly stable, NIR fluorescent, nontoxic, biocompatible, and highly excreted compound th

75 ts that can be accessed from inexpensive and nontoxic bismuth salts.

76 rough one-step rapid polycondensation of two nontoxic building blocks: L-cystine ester and versatile

77 In the environment, conjugated estrogens are nontoxic but may hydrolyze to their potent unconjugated,

78 ducts of the polynitro-CNT decomposition are nontoxic: carbon dioxide and molecular nitrogen.

79 The method employs inexpensive and nontoxic catalyst (iron(II) bromide) and reductant (zinc

80 Finally, an optimized nontoxic cationic NP contrast agent was evaluated in an

81 profile similar to plant safeners, which are nontoxic chemicals stimulating detoxification pathways i

82 ural constructs treated with 34 toxic and 26 nontoxic chemicals.

83 A reliable nontoxic CNI-free regimen may ultimately require the com

84 stems, both IF-MoS2 and INT-WS2 NPs remained nontoxic compared to equivalent concentrations (up to 10

85 iation (lambda > 400 nm), in contrast to the nontoxic compound 7, which is in accord with the results

86 Furthermore, we show that a nontoxic compound, cannabidiol, significantly downregula

87 etylates processed McC, converting it into a nontoxic compound.

88 osed human hepatoma cells (Huh7) to 0.5 muM (nontoxic concentration), 5 muM (EC50 concentration), 25

89 of RG7112 to human xenograft-bearing mice at nontoxic concentrations caused dose-dependent changes in

90 We found that nontoxic concentrations of HG-829 restored sensitivity t

91 lcicytes allow for fast calcium flow at low, nontoxic concentrations through undifferentiated cells b

92 Cell culture studies revealed that 4-HNE, at nontoxic concentrations, sensitized hepatocytes to TNF k

93 e reduction in a colon cancer mouse model at nontoxic concentrations.

94 Finally, development of new nontoxic conditioning regimens for HCT that can be safel

95 Dp44mT were easily mitigated by addition of nontoxic copper chelators or N-acetylcysteine, indicatin

96 etermine its speciation as either relatively nontoxic Cr(III) or toxic Cr(VI) and elucidate the influ

97 adsorption and reduction of toxic Cr(VI) to nontoxic Cr(III).

98 Being naturally nontoxic, CRM197 is an ideal carrier protein for conjuga

99 Playing it safe: The nontoxic cyanide source K4 [Fe(CN)6].3H2O can be used fo

100 These nontoxic D-amino acids preferably label the sites of act

101 ormation of chlorobenzene via benzene to the nontoxic degradation products, CO2 and CH4.

102 ntitumor activity of neomycin and neamine (a nontoxic derivative of neomycin), BCBL-1 cells were inje

103 tes BMMSCs and that restoring H2S levels via nontoxic donors may provide treatments for diseases such

104 the external environment, MDMA at a moderate nontoxic dose (9 mg/kg or ~1/5 of LD50 in rats) can caus

105 nogenic fraction of ALL blast cells, and, at nontoxic dose levels, exhibited potent in vivo antileuke

106 s.c. B16F10 melanoma model, we found that a nontoxic dose of IL-2 immunocytokine synergized with tum

107 adiation in SiHa human tumor xenografts at a nontoxic dose.

108 ts and demonstrate that clinically relevant, nontoxic doses of 5-azacytidine can restore erythropoiet

109 n of the spinal cord, systemic injections of nontoxic doses of amphotericin B and another activator,

110 Nontoxic doses of brefeldin A also prevented the dorsal

111 We show that nontoxic doses of l-buthionine sulfoximine increase the

112 Elevated, nontoxic doses of manganese (Mn) protect against Shiga t

113 Supplementation with nontoxic doses of micronutrient selenium has been shown

114 Furthermore, mice injected with nontoxic doses of Mn(2+) were completely resistant to a

115 At nontoxic doses, 1 promoted osteogenic differentiation.

116 as when administered at supraphysiologic but nontoxic doses.

117 Thus, CPOs can be regarded as novel nontoxic drug candidates for tumor microenvironment targ

118 so, therapy with stable, less-expensive, and nontoxic EGFR peptide mimics will block EGFR signaling a

119 Also, the use of enriched stable isotopes of nontoxic elements will have negligible health effects or

120 In addition to being made of abundant and nontoxic elements, we show that this material behaves as

121 , water consumption, pesticide toxicity, and nontoxic emissions linked to fertilizer use.

122 Because it is a natural, nontoxic, environmentally benign cobalt complex, cobalam

123 ive dechlorination of chlorinated ethenes to nontoxic ethene in contaminated aquifers.

124 ced dechlorination of chlorinated ethenes to nontoxic ethene was observed long after the expected nZV

125 We used nontoxic eutectic gallium-based alloys as a reaction sol

126 d on the cell membrane by treatment with the nontoxic FDA approved drug, trimethoprim.

127 novel system, which employs an inexpensive, nontoxic [Fe(III)Pc] catalyst (typically used as an indu

128 egation reaction could be modulated to favor nontoxic fibrils over toxic fibrils.

129 inding and activation of a cell-permeant and nontoxic fluorogenic ligand (a so-called fluorogen).

130 f relapsed and chemotherapy-resistant BPL at nontoxic fmol/kg dose levels.

131 ve toward the analyzed cell lines and almost nontoxic for healthy cell, indicating a high specific ac

132 CpG(A)-STAT3 siRNA is immunostimulatory and nontoxic for normal human leukocytes in vitro.

133 zed that the latter may bind and stabilize a nontoxic form of Abeta, thereby preventing its aggregati

134 CRM197 is an enzymatically inactive and nontoxic form of diphtheria toxin that contains a single

135 rposes, including macromolecular antigens, a nontoxic form of Pseudomonas aeruginosa exotoxin A (ntPE

136 romote aggregation of toxic oligomers into a nontoxic form, with a different morphology that cannot b

137 re able to sequester metals into subcellular nontoxic forms and maintain a low portion of metals dist

138 the angiogenesis inhibitor Lodamin, an oral nontoxic formulation of TNP-470, significantly decreased

139 While many substances were nontoxic, frequent disclosures also included notorious g

140 d toxin-like lectin genes repeatedly for new nontoxic functions.

141 We report the discovery of nontoxic fungicide fenarimol (1) as an inhibitor of Tryp

142 f the hydroxyguanidine moiety and provided a nontoxic group that could be easily bioactivated by glyc

143 HD was oxidized to the nontoxic HD-sulfoxide.

144 in inside the infected erythrocytes, forming nontoxic hemozoin crystals from large quantities of heme

145 c, so malarial parasites crystallize heme to nontoxic hemozoin.

146 All conjugates were nontoxic (IC(50) > 100 muM) to HT-29 cells, both in the

147 We discovered that fibers are nontoxic if they are washed free of adsorbed nonfibrilla

148 etes by the absence of potent, specific, and nontoxic immunosuppressive drugs.

149 forms of drug resistance, and are active and nontoxic in animal infection models.

150 them effective orally and both curative and nontoxic in doses that are equivalent to those of intrav

151 st--KD, B2, B3, and R--are highly active and nontoxic in Drosophila and that KD, B2, B3, and the wide

152 tructs engineered to be cytoplasmic are also nontoxic in HEK293 cells.

153 ed time course anticonvulsant studies, being nontoxic in subacute toxicity studies.

154 All BODIPYs were nontoxic in the dark (IC50 > 200 muM) and showed low pho

155 The complex is nontoxic in the dark, with cellular clearance within 96

156 hree protein components of anthrax toxin are nontoxic individually, but they form active holotoxin co

157 ene expression levels by administration of a nontoxic inducer will have positive effects on the safet

158 dentification of NEU-617 (1) as a potent and nontoxic inhibitor of proliferation for the HAT pathogen

159 R) may be reversed by selective, potent, and nontoxic inhibitors of ABCG2.

160 Glutamine serves, with alanine, as a major nontoxic interorgan ammonia carrier.

161 -4-one (11b) acted on the US28 receptor as a nontoxic, inverse agonist.

162 rties allowed the selection of 11 (INF39), a nontoxic, irreversible NLRP3 inhibitor able to decrease

163 lead, compound 4, was relatively potent and nontoxic, it exhibited poor stability to oxidative metab

164 osomes containing either silica particles or nontoxic latex particles.

165 H3PbI3, demonstrating that it is a promising nontoxic lead-free replacement for lead iodide perovskit

166 were chosen at approximately IC40 and IC10 (nontoxic) levels.

167 cells processed via a sol-gel process using nontoxic, low boiling point mixed solvents.

168 triking effect was explained by formation of nontoxic metabolites after 1 h incubation in human liver

169 f-life of 160 min, resulting in formation of nontoxic metabolites.

170 This method employs an inexpensive, nontoxic metal source (copper) and incorporates a stable

171 tion conditions using a cheap, abundant, and nontoxic metal.

172 ly relevant, because it provides an easy and nontoxic method to isolate liver stem cells from normal

173 agents were perhydrolyzed to the respective nontoxic methylphosphonic acids.

174 nic populations of Microcystis spp., whereas nontoxic Microcystis spp. strains were dominant in more

175 ons in the buccal network of Aplysia at low, nontoxic Mn(2+) concentrations.

176 CPMV nanoparticles are stable, nontoxic, modifiable with drugs and antigens, and their

177 We suggest that treatment with the small, nontoxic molecule AS101 may be an effective early therap

178 osed to reduce all air contaminants to small nontoxic molecules (e.g., H(2)O and CO(2)).

179 We identified 3 novel, nontoxic molecules demonstrating selective bacterial upt

180 se compounds, we selected the ten top-ranked nontoxic molecules proposed to be experimentally tested

181 t action of cholera toxin (CT) and two novel nontoxic molecules, multiple-mutated CT (mmCT) and doubl

182 igomers in order to maintain the presence of nontoxic monomers and to prevent fibrillization.

183 onto brain membranes much more rapidly than nontoxic monomers and were recovered in part as bound to

184 -antigen and core sugars (OAg) of LPS to the nontoxic mutant of diphtheria toxin (CRM(197)).

185 We assessed whether a nontoxic mutant of Escherichia coli heat-labile enteroto

186 We found that diphtheria toxin and its nontoxic mutant, called CRM197, can interact with HS.

187 iation at pH 7.4 results in the formation of nontoxic, native monomers.

188 ignificantly increased by treatment with the nontoxic, natural disaccharide trehalose.

189 We chose to use trehalose, a nontoxic naturally occurring disaccharide that is found

190 Nontoxic nature and cell membrane permeability are key f

191 by Clostridium botulinum and associates with nontoxic neurotoxin-associated proteins to form high-mol

192 f a highly photostable, renal clearable, and nontoxic new NIR probe (CyG) for precise quantification

193 hat PCDD/Fs are reductively dechlorinated to nontoxic non-2,3,7,8 PCDD/F congeners in sewers and land

194 However, nontoxic, nonbactericidal polymyxin derivatives have bee

195 entirely of Earth-abundant elements and are nontoxic, nonflammable, and safe for use in residential

196 ture of a BoNT in complex with a clostridial nontoxic nonhemagglutinin (NTNHA) protein at 2.7 angstro

197 These oligomeric solvents are nontoxic, nonvolatile, and recyclable alternatives to he

198 erapeutic targets, and develop effective and nontoxic novel agents against these targets.

199 duction of engineered nanoparticles that are nontoxic or biocompatible, and also allow for the design

200 hic amphipod Melita plumulosa was exposed to nontoxic or reproductively toxic concentrations of coppe

201 excellent radioprotection in mice at single nontoxic oral dose by a dose-reduction factor of 1.28.

202 It is nontoxic, orally bioavailable, metabolically stable, and

203 igated the influence of selected natural and nontoxic organic macromolecules (carboxymethyl cellulose

204 57 mug L(-1) year(-1)), there was a shift to nontoxic, organic aluminum.

205 Importantly, the nontoxic orlandin significantly reduced P. falciparum in

206 using a TEMPO oxoammonium salt as a mild and nontoxic oxidant has been developed.

207 ahead to the development of efficacious and nontoxic PAI-1 inhibitors as anticancer agents.

208 committed cells to death in response to the nontoxic palmitoleate treatment.

209 -uridine phosphoramidate nucleotide 16, as a nontoxic pan-genotypic anti-HCV agent.

210 ith cotreatment with Abeta12-28P, which is a nontoxic peptide antagonist of ApoE/Abeta binding.

211 analysis indicated limited formation of the nontoxic phosphoric acid ester but the formation of nonv

212 This precious metal-free and nontoxic photocatalytic system displays better performan

213 Here we present data that at high nontoxic physiological concentrations, bilirubin inhibit

214 a suggest that this self-assembling, largely nontoxic platform may have broad utility for the specifi

215 of the qualities of an ideal reagent: it is nontoxic, plentiful, and inexpensive.

216 Here, we report that nontoxic poly(ethylene glycol)-functionalized hydrophili

217 d scaffold-hopping approach, more potent and nontoxic polyamido derivatives were identified, highligh

218 In this study, we examined a novel class of nontoxic polycationic compounds initially designed as un

219 ratively the immunological imprints of inert nontoxic polystyrene nanoparticles 50 nm in diameter (PS

220 lectively oxidizes CEES to the comparatively nontoxic product 2-chloroethyl ethyl sulfoxide (CEESO) w

221 ) is exclusively and rapidly degraded to the nontoxic product EMPA (ethyl methylphosphonic acid) even

222 or rapid and efficient VX degradation to the nontoxic product EMPA (ethyl methylphosphonic acid).

223 ers and can be designed to depolymerize into nontoxic products.

224 ation processes that will ultimately lead to nontoxic products.

225 lead(II) acetate, bismuth is used due to its nontoxic properties, as Bi(III) has been a reagent in me

226 unable to distinguish ricin from RCA 120, a nontoxic protein also found in the castor bean plant.

227 patients and not showing cross-reactivity to nontoxic proteins such as maize, soya, and rice.

228 n relationship in PSMs, our study identifies nontoxic PSMalpha3 derivatives for active vaccination st

229 report in this paper the identification of a nontoxic quinoline carboxylic acid that reverts the inhi

230 = 4 h at 25 degrees C, using inexpensive and nontoxic reagents (NaCl, diluted HCl, water).

231 ve bioorthogonal "click" reactions employing nontoxic reagents are in high demand for their great uti

232 -forming toxin, equinatoxin II (Eqt), into a nontoxic reporter termed Eqt-SM and used it to monitor i

233 to disintegrate the artificial scaffold into nontoxic residues with smaller dimensions to ensure rena

234 on to the advantages of being a nonvolatile, nontoxic, reusable solvent, this hydrocarbon polymer sol

235 oxic hIAPP peptide and the nonamyloidogenic, nontoxic rIAPP peptide remain unclear.

236 The nontoxic RL treatment is attractive for clinical develop

237 Conclusion:(68)Ga-NOTA-UBI is considered a nontoxic, safe-to-administer radiopharmaceutical unlikel

238 (AC) amendments to sediments were tested for nontoxic, secondary effects on survival, weight change,

239 Furthermore, the nontoxic, self-replicating amyloid conformers of yeast p

240 Furthermore, nontoxic short UGGAA repeat RNA suppressed mutated RBP a

241 r QS, and suppression can be relieved by the nontoxic small molecule quinic acid.

242 of DU011, our previously discovered potent, nontoxic, small-molecule inhibitor of UPEC polysaccharid

243 s approaches for development of inexpensive, nontoxic solar cell contacting pastes.

244 llization while stabilizing its monomers and nontoxic soluble assemblies of nonfibrillar morphology.

245 3-phenylprop-2-enoate (ethyl cinnamate) as a nontoxic solvent-based clearing reagent that can be hand

246 oxic conformer compared with non-aggregated, nontoxic species or mature fibrils.

247 However, recent studies demonstrated that nontoxic STa derivatives (toxoids), after being fused to

248 rt through its effect on REV1 is a promising nontoxic strategy to increase p53-dependent cell death a

249 Nanodiamonds are of interest as nontoxic substrates for targeted drug delivery and as hi

250 Quantitative uptake studies of a nontoxic Tb-containing compound by individual cells were

251 Specifically, we demonstrate that the nontoxic tellurium compound AS101, currently being evalu

252 These features of ESKM make it a promising nontoxic therapeutic agent for sensitive and resistant P

253 ding on these results, we developed a novel, nontoxic therapeutic strategy to target dormant breast c

254 gest that DMA represents a newly discovered, nontoxic therapy for a broad range of inflammatory disor

255 Monophosphoryl lipid A (MPLA), a nontoxic TLR4 ligand derived from lipopolysaccharide (LP

256 vailable D-amino acids, which are relatively nontoxic to animals and microbes, to either select again

257 cations such as sodium, were observed to be nontoxic to both normal and cancer cells.

258 studies indicated that SBDs are essentially nontoxic to cells at concentrations as high as 250 mg/kg

259 2 is nontoxic to cells, but potently cytotoxic to cancer cell

260 p90, the oligomers are rendered harmless and nontoxic to cells.

261 17-HDHA did not affect proliferation and was nontoxic to cells.

262 The complexes were nontoxic to either bacterial or mammalian cells.

263 hly active to cancer cells and less toxic or nontoxic to fibroblasts.

264 oxicity studies reveal that the alt-PASs are nontoxic to HEK, HeLa, and NIH3T3 cells.

265 gents were shown to be chemically stable and nontoxic to HEK293T cells at concentrations as high as 5

266 ar growth of Mycobacterium tuberculosis, are nontoxic to human cell lines, and are active against mul

267 in the limits of detection of our assays, is nontoxic to human cells in vitro.

268 anti-HIV and anti-HBV inhibitor, while being nontoxic to human hepatoblastoma cells.

269 as PLLA is biocompatible, biodegradable and nontoxic to humans.

270 nm aggregates, the aggregates are stable and nontoxic to macrophage cells up to 55 x 10(-3) m Au.

271 en coadministered with 36 (at concentrations nontoxic to mammalian cells), the minimum inhibitory con

272 While nontoxic to mammalian cells, the single-site variant has

273 The peptide was bactericidal and nontoxic to mammalian cells.

274 FPS-ZM1 was nontoxic to mice and readily crossed the blood-brain bar

275 Most notably, MI-2 was nontoxic to mice, and displayed selective activity again

276 Nontoxic to myeloma cells when used as a single agent, 4

277 In addition, CQ is nontoxic to neuronal cells and shows significant blood b

278 allow production of nanoparticles which are nontoxic to normal cells and toxic to cancer cells.

279 and human MPNST cell lines, while remaining nontoxic to normally dividing Schwann cells or mouse emb

280 aken up by cultured human hepatoma cells, is nontoxic to the cultured cells and a xenotransplantation

281 cellent activity at concentrations that were nontoxic to the killer cells, and several were a signifi

282 tably, the optimized molecule is shown to be nontoxic toward human cells (HEK 293) at a concentration

283 Nontoxic toward mammalian cells, these rapidly bacterici

284 to miltefosine (IC50 = 8.4 +/- 2.1 muM) and nontoxic toward the J-774A.1 cell line and Vero cells.

285 kB antagonist cyclotraxin-B was fused to the nontoxic transduction domain of the tat protein from hum

286 to overcome using siRNA, we also developed a nontoxic transfection vector: poly(lactic-coglycolic aci

287 A new class of nontoxic triaryl benzimidazole compounds, derived from e

288 An effective, nontoxic, tumor-specific immunotherapy is the ultimate g

289 merized right after use, the best siCPDs are nontoxic under conditions where cell-penetrating peptide

290 ults demonstrate that doses of MDMA that are nontoxic under cool, quiet conditions can become highly

291 , whereas colloidal silicas were essentially nontoxic under identical treatment conditions.

292 ct based HDAC inhibitors, 4a was found to be nontoxic under in vivo conditions.

293 equently encountered in clinical practice in nontoxic uninodular or multinodular goiter.

294 The identification of nontoxic variants of L9 strongly suggests that it is a n

295 d cell tropism of HSV, our design provides a nontoxic vector that can accommodate large transgene con

296 Importantly, the nontoxic, vinyl ether duocarmycin double prodrug was suc

297 compared to a single infection at a higher, nontoxic, viral dose.

298 dly without inducing drug resistance and was nontoxic when applied topically.

299 Fatty acids like oleate (18:1Delta9) were nontoxic, whereas palmitoleate (16:1Delta9) was a potent

300 insoluble and stable Abeta species that were nontoxic which indicates that p-FTAA might have therapeu