ライフサイエンスコーパス: nontoxigenic

1 %) were the most common; three isolates were nontoxigenic.

2 eaction was used to analyze 50 toxigenic, 39 nontoxigenic, and 2 toxin-defective isolates.

3 results indicate that whereas both ETBF and nontoxigenic B. fragilis (NTBF) chronically colonize mic

4 Studying a collection of ETBF and nontoxigenic B. fragilis (NTBF) strains, we found that b

5 Strains that do not secrete BFT are nontoxigenic B. fragilis (NTBF), and those that do are c

6 the bft gene can be transferred from ETBF to nontoxigenic B. fragilis strains by a mechanism similar

7 ly for C. difficile common antigen contained nontoxigenic bacteria.

8 were therefore used to test the ability of a nontoxigenic C-terminal domain (CTD) fragment of TcdB to

9 is prevented in hamsters by colonization by nontoxigenic C. difficile after administration of clinda

10 t observed when HIOs were colonized with the nontoxigenic C. difficile strain F200, we directly teste

11 Nontoxigenic C. difficile strain M3 colonized the gastro

12 ent with antibiotics, we gave a Cm-resistant nontoxigenic C. difficile strain, M13 (minimal inhibitor

13 cting alterations within both, toxigenic and nontoxigenic C. difficile strains after vancomycin treat

14 Furthermore, simultaneous monitoring of nontoxigenic C. difficile strains is not possible, due t

15 The benefits of use of Cm-resistant nontoxigenic C. difficile to prevent CDAD must be balanc

16 no cross-reactions with other enterotoxins, nontoxigenic C. difficile, or other Clostridum species.

17 Since culture is tedious and also detects nontoxigenic C. difficile, we conclude that culture is m

18 oxigenic C. difficile (TCD), and 15 (6%) had nontoxigenic C. difficile.

19 phenotypic testing classified the strain as nontoxigenic C. diphtheriae biotype Gravis.

20 We studied the predominant strain of nontoxigenic C. diphtheriae circulating in the United Ki

21 A total of 26 nontoxigenic C. diphtheriae strains isolated in the Unit

22 genic Corynebacterium diphtheriae strains, 9 nontoxigenic C. diphtheriae strains, and 44 strains repr

23 were infected with toxigenic cag-positive or nontoxigenic cag-negative strains of H. pylori or isogen

24 Groups of 10 hamsters were given 10(6) nontoxigenic CD spores 2 days after receiving a single d

25 to test the efficacy of colonization with 3 nontoxigenic CD strains for preventing CDAD after exposu

26 Colonization with nontoxigenic CD strains is highly effective in preventin

27 associated with failure of colonization with nontoxigenic CD.

28 Nontoxigenic Corynebacterium diphtheriae and Corynebacte

29 ation of the resident CTX prophage-producing nontoxigenic derivatives at a high frequency.

30 l loss of the additional copies of rstC, the nontoxigenic derivatives can act as precursors of new to

31 rfbE(EcO157:H7) is conserved in nontoxigenic E. coli O157 strains expressing a variety o

32 ve humidity (30%), culturable amounts of the nontoxigenic E. coli O157:H7 strain ATCC 700728 and the

33 ed pathogenic E. coli, but it is absent from nontoxigenic E. coli O55:H7, sorbitol-fermenting Stx-pro

34 Nontoxigenic El Tor O1 V. cholerae infection is characte

35 hat involved enterotoxin genes cloned into a nontoxigenic fimbriated strain have suggested that LT bu

36 ulture cytotoxicity assay and were therefore nontoxigenic for diagnostic purposes.

37 cific antisera or active immunization with a nontoxigenic form of Hla significantly reduced the size

38 Active immunization with nontoxigenic Hla(H35L) or passive immunization with neut

39 These isolates were found to be nontoxigenic in the Vero cell tissue culture cytotoxicit

40 ffers dramatically from the host response to nontoxigenic infection or vaccination, where neutrophils

41 cholera toxin-producing strains, similar to nontoxigenic infection, accessory toxins are critical to

42 lonized with either toxigenic H. pylori or a nontoxigenic isogenic mutant.

43 is highly stable in toxigenic C. difficile, nontoxigenic isolates lack the unit, and isolates with a

44 toxigenic isolates; these were absent in the nontoxigenic isolates.

45 those of the Elek test: 87 toxigenic and 158 nontoxigenic isolates.

46 is was greatly reduced in mice infected with nontoxigenic mutants.

47 A3R (pXO1(+) pXO2(-)) and the totally cured, nontoxigenic, nonencapsulated RA3:00 (pXO1(-) pXO2(-)).

48 Consistently, nontoxigenic or toxigenic isolates that lack one, two, o

49 Toxigenic and nontoxigenic P. multocida isolates cannot be differentia

50 of steps from O55:H7, a recent ancestor of a nontoxigenic pathogenic clone associated with infantile

51 These findings suggest that nontoxigenic precursors of the two V. cholerae O1 biotyp

52 Nontoxigenic protein A (SpA(KKAA)), when used as an immu

53 e report a bloodstream infection caused by a nontoxigenic strain of C. diphtheriae and discuss the ep

54 Each nontoxigenic strain prevented disease in 87%-97% of hams

55 Clostridium difficile strain CD37, the first nontoxigenic strain sequenced.

56 0 was replaced with the s2 sequence from the nontoxigenic strain Tx30a) or a VacA mutant protein (Vac

57 s.c. B. anthracis infection (an encapsulated nontoxigenic strain), we show that concomitant administr

58 l recruitment compared to mice infected with nontoxigenic strains and neutrophil depletion prior to i

59 ate that, if lysogenised by a bacteriophage, nontoxigenic strains circulating in the United Kingdom c

60 The site of integration in three nontoxigenic strains contained a 17-bp GC-rich sequence

61 ated in the United Kingdom during 1995 and 4 nontoxigenic strains isolated in other countries were an

62 ants of the predicted DtxR protein among the nontoxigenic strains isolated in the United Kingdom.

63 Nontoxigenic strains of Corynebacterium diphtheriae repr

64 from patients infected with VacA(+), but not nontoxigenic strains of H pylori, had increased levels o

65 ere infected with cag(+) toxigenic or cag(-) nontoxigenic strains of H. pylori or isogenic mutants.

66 The expression of fpn by both toxigenic and nontoxigenic strains suggests that this protease may con

67 Ten of the phenotypically nontoxigenic strains were found to contain fragment A of

68 atients infected with toxigenic (VacA(+)) or nontoxigenic strains.

69 epidemic and pandemic strains but absent in nontoxigenic strains.

70 rapid differentiation between toxigenic and nontoxigenic strains.

71 echanism of cholera toxin gene transfer into nontoxigenic V. cholerae isolates, including strains tha

72 e report two unassociated cases of nonfatal, nontoxigenic V. cholerae non-O1, non-O139 bacteremia in

73 A library of 8,734 nontoxigenic V. cholerae strains carrying transcriptiona

74 -T1ts can replicate and integrate into these nontoxigenic V. cholerae strains with high efficiency.

75 ked derivative of the CTX prophage into four nontoxigenic V. cholerae strains, including two V. chole

76 ted with wild-type ETBF (WT-ETBF) strains, a nontoxigenic WT strain of B. fragilis (WT-NTBF), WT-NTBF