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1 level of </=2 IU per deciliter, or </=2% of normal levels).
2 oxp3- effector T cells (Teffs) remained at a normal level.
3 py and the return of the platelet count to a normal level.
4 the epithelial barrier function to a nearly normal level.
5 t-induced secretion of bFGF and VEGF to near normal levels.
6 NAT2 expression in rTg4510 tauopathy mice to normal levels.
7 XCL13 at relapse including 3 with previously normal levels.
8 ntact time between secretion and EGJ towards normal levels.
9 tored M3R-stimulated insulin release to near normal levels.
10 lial damage (thrombomodulin) markers to near-normal levels.
11 ation patient lymphoblasts restores MeCP2 to normal levels.
12 ors and increased expression of TGF-beta1 to normal levels.
13 stablished measure of muscle damage, to near-normal levels.
14 ly restores p70S6K activity and cell size to normal levels.
15 ted basally and were increased by insulin to normal levels.
16 ths after transplantation, but did not reach normal levels.
17 thylakoid membrane complexes accumulated to normal levels.
18 by restoring penile PDE5 gene expression to normal levels.
19 class switching from IgM to IgG1 at 5-10% of normal levels.
20 le were still present at 50% (or greater) of normal levels.
21 reas renal EPO was down-regulated to 6.7% of normal levels.
22 "liking" reactions to approximately one-half normal levels.
23 : then, a year or so later, they declined to normal levels.
24 ostnatal proliferation and spatial memory to normal levels.
25 eficient animals express slow fiber genes at normal levels.
26 o I-SceI-dependent class switching at almost normal levels.
27 tructure brought the PLP1/DM20 ratio to near normal levels.
28 c triglyceride levels were fully restored to normal levels.
29 main-containing inositol 5'-phosphatase 1 to normal levels.
30 pair, the extension rate recovered to nearly normal levels.
31 ry state induced by periadolescent MK-801 to normal levels.
32 The mitochondrial DNA was also detected at normal levels.
33 rapid weakening of activity to near or below normal levels.
34 mokines, and antimicrobial peptides) to near-normal levels.
35 DL-C and apoB into sd-LDL and lb-LDL to near normal levels.
36 ey hyperaccumulate copper up to 50-fold over normal levels.
37 lity transition pore opening was restored to normal levels.
38 rogramming efficiency of somatic FA cells to normal levels.
39 rs in lymph nodes and spleen were at or near normal levels.
40 id not affect the growth CRC cell lines with normal levels.
41 ormed abnormal complexes but were present at normal levels.
42 decrease in IL excitability was increased to normal levels.
43 s likely to have periodontitis as those with normal levels.
44 utant nodules increased nitrogen fixation to normal levels.
45 nt with dichloroacetate restored PDH flux to normal levels (0.018 +/- 0.002 s(-1)), reversed diastoli
46 <240 U/L), albumin level, 2.6 g/dL (26 g/L) (normal level, 3.5-5.0 g/dL [35-50 g/L]), and creatinine
47 Interestingly, c-Jun protein rebounded to normal levels 4 h following U0126 exposure but not after
48 or overall survival compared with those with normal level (60.0% vs. 83.6%, log-rank test, p = 0.035)
54 ed increased mortality that declines to near-normal levels after the first several years, but in our
55 ction, increasing NS1 SUMOylation beyond its normal levels also exerted a negative effect on its IFN-
56 ibrin generation to approximately 78% of its normal level and hence improve clot formation under dilu
57 y), disrupted by IR injury, were restored to normal level and the induction of ventricular tachycardi
58 orms, but those for lean mass remained below normal levels and diminished significantly over time (P
59 -DG in the regenerating fibers reaches up to normal levels and lasts for >4 weeks, but no up-regulati
60 TLR2 signaling restored the inflammation to normal levels and the ability to clear Lm in Pxr(-/-) mi
61 the protein product was expressed at nearly normal levels and was functional in the NKTCL cell lines
62 etter restoration of complete blood count to normal level, and significantly longer median survival a
63 Csf1r were expressed on the cell surface at normal levels, and bound CSF1, but were not able to sust
64 PS I content and activities were restored to normal levels, and cells again produced thylakoids that
65 cy of cell division when DamX is produced at normal levels, and inhibiting cell division when DamX is
66 ls, increased serum levels of ALT (even high-normal levels) are associated with markers of cardiovasc
67 degree of disease activity, and increased to normal levels as a result of anti-TNF-alpha therapy.
71 KO triple mice reduced the liver size to the normal level by decreasing lipid storage in both hepatoc
72 BP1-knockdown Huh7.5 cells was restored to a normal level by downregulation of either p53 or BCCIP.
73 the peripheral T cells were repopulated to a normal level by syngeneic bone marrow transplantation.
75 served when the BLMAP was decreased to below normal levels by an infusion of sodium nitroprusside.
77 Remarkably, returning Mtor and Rictor to normal levels by deleting one allele of Mtor and one all
78 patient's fibroblasts were also restored to normal levels by exogenous expression of wild-type MRPS7
81 The salt tolerance of sos2 was restored to normal levels by wild-type SOS2, but not by a mutated fo
82 in cancer cell lines to approximately 50% of normal levels causes a delay in the cell cycle and accum
83 st, thymus markers were delayed but achieved normal levels, concurrent with complete loss through apo
84 cells restored alveolar fluid clearance to a normal level, decreased inflammation, and were associate
85 nthesis restored cytokine production to near-normal levels, delayed ACS progression, and extended hos
86 th nocodazole restored Plk1 activity to near normal levels, demonstrating that MTs also contribute to
87 g extracellular matrix stiffness relative to normal levels disrupts junctional integrity and increase
90 CD3 T-cell counts gradually recovered to normal levels during this period but CD8 T cells recover
91 these circulating microRNAs decrease toward normal levels during treatment with N-acetyl cysteine (N
92 can be manipulated to enhance GSIS to supra-normal levels even in the face of defective mitochondria
93 mice with PPARgamma expression at 25% of the normal level exhibited high autoantibody levels and deve
94 tored dopamine neuron population activity to normal levels following CMS; LHb inactivation had no res
96 sed BMI, but not sex, influences recovery to normal levels for the markers studied, possibly indicati
97 uals who maintained or decreased their BP to normal levels had the lowest remaining LTR for CVD, 22%
99 onditionally reduce ATR expression to 10% of normal levels in adult mice to compare the impact of thi
100 ed mice, DHT implants restored SV weights to normal levels in alphaERKO mice but not in WT mice, sugg
101 he enhanced response to PM(2.5) plus O(3) to normal levels in an established model of chronic allergi
103 ome that is elevated in PWID, can regress to normal levels in former injection drug users who are HCV
104 levels were elevated on average 5-fold above normal levels in hematologic patients receiving voricona
106 s DEmiRs and target DEGs to their respective normal levels in inflammation, mitochondrial function an
107 model, Mybl2 knockdown by RNAi to 20-30% of normal levels in multipotent hematopoietic progenitors r
109 me activity for 6 mo at approximately 30% of normal levels in one animal, and in excess of normal lev
111 irus (HIV) infection but can recover to near normal levels in patients who spontaneously control vire
112 Serum thrombopoietin (TPO) was maintained at normal levels in Pf4-Cre-positive Jak2(f/f) mice, consis
114 (citZ) transcript was present at higher-than-normal levels in the citB null mutant, due at least in p
116 enerated mice in which Mecp2 remains at near normal levels in the nervous system, but is severely dep
117 , assessed by western blot, was below 15% of normal levels in the nine mutation carriers in whom this
121 in IL-17-producing cells was not restored to normal levels in wild-type and Blimp-1CKO-mixed bone mar
122 aneously restoring fibrinogen (to 88% of its normal level) in diluted blood can restore fibrin genera
124 s likely to have periodontitis as those with normal levels (</=199 mg/dL), and those with STC >/=240
126 l level, <300 U/L); amylase level, 1435 U/L (normal level, <140 U/L); lactate dehydrogenase level, 25
127 phosphatase level of 85 U/L (1.42 mukat/L) (normal level, <142 U/L [2.37 mukat/L]), a serum creatini
128 0.8-2.0), a urine protein level of 15 mg/dL (normal level, <20 mg/dL), a total serum calcium level of
129 U/L); lactate dehydrogenase level, 253 U/L (normal level, <240 U/L), albumin level, 2.6 g/dL (26 g/L
130 ge, 1.1-1.3 mmol/L); lipase level, 2423 U/L (normal level, <300 U/L); amylase level, 1435 U/L (normal
131 glutamyl transferase (77 U/L [1.28 mukat/L]; normal level, <55 U/L [<0.92 mukat/L]) and C-reactive pr
132 -reactive protein (97.1 mg/L [924.8 nmol/L]; normal level, <8 mg/L [<76.2 nmol/L]]) levels were chron
133 phorylase activity rose from undetectable to normal levels (median 697 nmol/h/mg protein, range 262-1
134 ABCB4(S320F) homozygosity, with half the normal level of ABCB4, is the tipping point between more
137 ration with densely aligned collagen fibers, normal level of cellularity, and functional restoration.
138 ERPs of a mouse line expressing 150% of the normal level of cone M-opsin with those of WT mice revea
140 vels of aSyn prevent Cdc5 from maintaining a normal level of GTP-bound Rho1, which is an essential GT
141 Here we show that Plc1p is required for a normal level of histone acetylation; plc1Delta cells tha
144 , such as TACI(+/-) mice, expressed half the normal level of TACI on their B cells and exhibited simi
145 ith Crohn's disease, and have shown that the normal levels of a key antimicrobial peptide produced by
146 anti-inflammatory eicosanoids, and restored normal levels of acylcarnithins but not of sphingomyelin
147 es (OR = 0.04, 95% CI 0.005-0.49; P = 0.01), normal levels of alanine aminotransferase at the end of
148 HBV) DNA who were positive for HBeAg and had normal levels of alanine aminotransferase were randomly
149 ith chronic HBV infection, high viral loads, normal levels of alanine aminotransferase, and therapy w
151 rtensive patients with hyperaldosteronism or normal levels of aldosterone exhibited increased activit
152 e channels but normal surface expression and normal levels of alpha and gamma subunit-activating clea
153 the relationship between low-normal and high-normal levels of ALT and an extended panel of cardiovasc
154 ts with CHB, undetectable serum HBV DNA, and normal levels of aminotransferases after long-term (4 or
157 dispersed in axons, thereby maintaining near normal levels of ATP even in boutons lacking mitochondri
159 efective in fusion activity and yet retained normal levels of attachment to cell surface heparan sulf
164 n2 cur1 double mutant are cured by restoring normal levels of Btn2p and Cur1p, with both proteins nee
165 rranged T cell receptor alphabeta transgene, normal levels of CD4 single-positive cells were produced
166 SCM) and CD4(+) central memory T cells, with normal levels of CD4(+) T(SCM) proliferation, and lack o
170 ivo, Fib(AEK) mice were generated that carry normal levels of circulating fibrinogen but lack the cap
171 Ablation of Erfe in Th3/+ mice restored normal levels of circulating hepcidin at 6 weeks of age,
172 activate Stat5 during late pregnancy despite normal levels of circulating serum prolactin and pituita
174 eficient B cells lack the ability to undergo normal levels of class switch recombination and somatic
175 ally, our model predicted that restoring the normal levels of clotting factors II, IX, and X while si
177 eins were differentially affected, with near normal levels of cytochrome c oxidase subunit2 and Nad7
178 reveals that both proteins are required for normal levels of cytosine methylation and hydroxymethyla
179 s that dictate the ability of DAT to sustain normal levels of DA clearance, we pursued a forward gene
182 morpholino, with the ability to induce near-normal levels of dystrophin, and restores function in bo
184 ynchronization as measures that characterize normal levels of excitability and quantify any deviation
186 lacking DdPpk1 accumulate approximately 50% normal levels of extracellular polyphosphate, suggesting
188 n certain rare genetic contexts, maintaining normal levels of FGFR2 signaling is important for human
189 e decay of mRNAs, but rather for maintaining normal levels of functional tRNAs and protein synthesis
190 females presented abnormal levels of Ga2 but normal levels of Gb3, supporting the importance of analy
192 wever, MEK1DD-expressing organoids exhibited normal levels of growth and retained apicobasal polarity
195 ut containing intact H2Bub enzymes that have normal levels of H3K4me3, suggesting that monoubiquitina
196 t with the GNAT proactivator SPV106 restored normal levels of H3K9Ac and H3K14Ac, reduced DNA CpG hyp
198 ceiving cognitive behaviour therapy achieved normal levels of health anxiety compared with those in t
199 xchange or infusion may transiently maintain normal levels of hematologic measures but does not treat
202 HIF1, but not HIF2 target genes in spite of normal levels of hypoxia-inducible transcription factor
203 nd that IFN-lambdaR1-deficient mice produced normal levels of IFN, robust NK cell responses, but grea
206 Patients with cells available for study had normal levels of IL-2-induced STAT5 phosphorylation.
208 d production of normal levels of virions and normal levels of infectivity in the complete absence of
210 Titrating ventilatory support to maintain normal levels of inspiratory effort may prevent changes
211 defects, SMA Schwann cells failed to express normal levels of key extracellular matrix proteins, incl
213 from some female strains, were necessary for normal levels of male investigatory behavior of female s
215 cells, tend to be multinucleate, accumulate normal levels of mass and protein per nucleus, and form
216 ls displayed normal morphology and contained normal levels of mast cell proteases before and after de
217 expressing the human MECP2 gene at twice the normal levels of MeCP2 (Tg1; Collins et al., 2004).
219 mice contained increased numbers of LC with normal levels of MHC and costimulatory molecules and T-c
221 nerate mouse hearts expressing 6- to 16-fold normal levels of microRNA (miR)-143, miR-378, and miR-49
222 female mice developed normally and produced normal levels of milk protein, suggesting a defect in de
224 e born to an iron-deficient mother contained normal levels of mitochondrial iron and no ferritin; the
230 fertile adults, with the capacity to produce normal levels of myeloid and lymphoid lineage cells.
231 immature and mature B cell subsets and have normal levels of naive serum Abs but altered levels of n
237 ve determined that this gene is required for normal levels of PME activity and homogalacturonan methy
238 otes show loss of enzymatic activity despite normal levels of precursor protein, and manifest a more
239 vity had often fully recovered, or overshot, normal levels of productivity in both high- and low-dive
240 rmed, with transduced cells exhibiting supra-normal levels of protein expression and ex vivo migratio
243 r are required at the preloaded promoter for normal levels of recruitment and activity of the general
245 genesis defect, allowing them to reestablish normal levels of ribosome production and cell proliferat
248 gth sleB [sleB(FL)] and ypeB [ypeB(FL)], but normal levels of SleB(FL) in spores required normal spor
249 exogenous TGF-beta in vitro, they maintained normal levels of Smad2 phosphorylation under steady-stat
250 As a reciprocal experiment, we restored normal levels of SMN in the muscle with low SMN levels i
254 variant that had enhanced Sse expression and normal levels of SpeB production was identified (the var
256 ion of one copy of the Icosl allele restores normal levels of T(fh) and GC B cells in Taci(-/-) mice.
257 schizophrenia, ChC cartridge boutons contain normal levels of the 67 kDa isoform of glutamic acid dec
258 AADC deficient patients fail to produce normal levels of the monoamine neurotransmitters dopamin
260 re, in vivo, CTNNBL1 is required to maintain normal levels of the Prp19 complex and to facilitate the
266 Genetic disruption of PGC1alpha rescued normal levels of type I fiber markers MyH7 and myoglobin
269 glycosylation, we demonstrated production of normal levels of virions and normal levels of infectivit
273 mice that express inactive plasmin (Pm) but normal levels of zymogen Pg (PAI-1(-/-)/Pg(S743A/S743A))
276 ive lignin peroxidase genes are expressed at normal levels or even higher in the laccase triple mutan
279 ion, in that the target remains present at a normal level prior to induction and is then rapidly depl
282 hment of GILZ expression in patients' DCs to normal levels restores their capacity to activate allerg
283 pression of two Msh3 polymorphic variants at normal levels showed no detectable change in expansions,
284 phase even if stratospheric ozone returns to normal levels, so that climate conditions conducive to w
285 restored F81Y S-opsin protein expression to normal levels, suggesting that ligand binding in the ER
287 and cytoskeletal proteins remained at their normal levels, the major peripheral membrane proteins sp
288 er, the median CD4 cell count remained below normal levels throughout follow-up period and the propor
290 nockdown (by approximately 85% compared with normal levels), using lentiviral shRNA, dramatically att
291 xia (AIH) restores phrenic nerve activity to normal levels via enhanced phrenic long-term facilitatio
297 ried in isolation from one-half to two-times normal levels while subjects with simulated amputation w
298 mic pressure gradient (PSG) was decreased to normal level, while total bilirubin (TBIL) and liver fun
300 ium cyclosilicate reduced serum potassium to normal levels within 48 hours; compared with placebo, al
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