ライフサイエンスコーパス: normothermia

1 tricular dP/dt (1.8 +/- 0.1 microg/kg/min at normothermia).

2 s C (hypothermia) or 36.5 to 37.5 degrees C (normothermia).

3 ; spleen: 72 +/- 5%, all P<0.001 relative to normothermia).

4 to 9% in normothermic controls (*p < .01 vs. normothermia).

5 o 2% for normothermic controls (*p < .05 vs. normothermia).

6 sociated with higher rates of intraoperative normothermia.

7 after injury: 119 to hypothermia and 113 to normothermia.

8 a random number generator to hypothermia or normothermia.

9 CBVC (P = 0.03) remained reduced relative to normothermia.

10 ldren randomized to moderate hypothermia vs. normothermia.

11 lure that is fully reversible upon return to normothermia.

12 re marked in animals subjected to continuous normothermia.

13 C was smaller during hypothermia than during normothermia.

14 for 48 hours by means of surface cooling, or normothermia.

15 led conditions of normoxia, normocarbia, and normothermia.

16 hypothermia vs. rats managed with controlled normothermia.

17 ermia increased blood pressure compared with normothermia.

18 er 3 min of hypoxia, this compares to 81% at normothermia.

19 or 24 hours followed by passive rewarming to normothermia.

20 ukin 6 and 8) during mild hypothermia versus normothermia.

21 s C followed by slow rewarming or controlled normothermia.

22 of decoding performance from hypothermia to normothermia.

23 stantially higher in mild hypothermia versus normothermia.

24 rdiopulmonary resuscitation was started with normothermia.

25 black with hypothermia and remain green with normothermia.

26 r 24 hrs patients were passively rewarmed to normothermia.

27 mins at 34 degrees C) compared with induced normothermia.

28 were principally similar to responses during normothermia.

29 nce interval 0.44-0.73, p</=.01) compared to normothermia.

30 stemic vascular resistance index not seen at normothermia.

31 d by 4 hrs of either moderate hypothermia or normothermia.

32 g (122 +/- 30 ml; mean +/- s.d.) compared to normothermia (110 +/- 20 ml; P = 0.06).

33 vels were elevated compared with baseline in normothermia (2.13 +/- 0.27 log pg/mL vs 0.27 +/- 0.17 l

34 ith intervention from 2 to 26 hours, to: (1) normothermia; (2) normothermia + 24 hours 50% inhaled xe

35 4 of 10,962 (18%) and 828 of 6,133 (14%) for normothermia, 235 of 1,046 (22%) for mild hypothermia, 2

36 rom 2 to 26 hours, to: (1) normothermia; (2) normothermia + 24 hours 50% inhaled xenon; (3) 24 hours

37 iven temperature (hyperthermia: -28% +/- 4%, normothermia: -27% +/- 6%, and mild hypothermia: -27% +/

38 at a pressure of 100 mm Hg (hyperthermia to normothermia: -28% +/- 3% and normothermia to mild hypot

39 uring heating (-48.7 +/- 6.7 ml) compared to normothermia (-33.2 +/- 7.4 ml) and to cooling (-10.3 +/

40 Thus, at normothermia (34 degrees C), the pore cutoff size for th

41 ted to external cooling (n = 101) to achieve normothermia (36.5-37 degrees C) for 48 hours or no exte

42 Rats were randomized to three groups: a) normothermia (37 degrees C + 0.5 degrees C); b) immediat

43 Normothermia (37 degrees C) attenuated IL-10 release fol

44 lusion performed under conditions of cranial normothermia (37 degrees C) or mild cranial hyperthermia

45 resuscitation hypothermia (at 33 degrees C), normothermia (37 degrees C), or hyperthermia (39 degrees

46 ent moderate or severe HI followed by 5 h at normothermia (37 degrees C), or one of five HT temperatu

47 aoperative hypothermia (t = 33 degrees C) or normothermia (37 degrees C).

48 r hypoxic (n = 6) gas levels and by 4 hrs of normothermia (37 degrees C).

49 ischemia followed by (a) 3 h of postischemic normothermia (37 degrees C); (b) 3 h of postischemic hyp

50 to either heat shock (43 degrees C, 1 hr) or normothermia (37 degrees C, 1 hr) and allowed to recover

51 e (VEH); FGF-2 (45 microg/kg/h for 3 h i.v.)+Normothermia (37+/-0.5 degrees C); FGF-2+Hypothermia (32

52 iddle cerebral artery occlusion under either normothermia (37.5 degrees C) or hypothermia (33 degrees

53 Normothermia (38 +/- 0.5 degrees C), fluid balance (5 mL

54 de infusion, animals were assigned to either normothermia (38 degrees C, n = 7) or mild hypothermia (

55 They were randomized to normothermia (38.0 +/- 0.5 degrees C) or mild hypothermi

56 he effects of hyperthermia (40.5 degrees C), normothermia (38.0 degrees C), and mild hypothermia (33.

57 andomized 42 newborn piglets: (Group i) sham-normothermia (38.5-39 degrees C); (Group ii) sham-33 deg

58 ergy requirements were measured at baseline (normothermia, 38-40 degrees C) and during treatment with

59 output was lower in mild hypothermia than in normothermia (4.5 +/- 0.4 L/min vs 6.6 +/- 0.4 L/min, p

60 heating (8.6 +/- 1.9 ml mmHg(1)) compared to normothermia (4.5 +/- 3.0 ml mmHg(1), P = 0.02).

61 LBNP was comparable to that observed during normothermia (4.8 +/- 2.3 ml mmHg(1); P = 0.78).

62 t) but in only 6 of 104 patients assigned to normothermia (6 percent, P = 0.009).

63 es 1 or 2 (hypothermia: 256 of 467 [55%] vs. normothermia: 69 of 165 [42%]) and survived for >180 day

64 >180 days (hypothermia: 315 of 467 [67%] vs. normothermia: 79 of 165 [48%]).

65 ial node activity in mild hypothermia versus normothermia (87 +/- 5 vs 47 +/- 5, normalized units, p

66 c tolerance by approximately 80% compared to normothermia (938 +/- 152 versus 182 +/- 57 CSI; mean +/

67 Furthermore, in normothermia, a significant increase of creatinine and a

68 substrate, chlorzoxazone, when compared with normothermia after cardiac arrest, 1.26+/-0.34 mL/min vs

69 ss in all 3 hypothermia groups compared with normothermia (all P<0.05).

70 at a pump flow of 2.4 L.min-1.m-2 at stable normothermia and approximately 15 minutes later after th

71 t concentration (150 mg/L) for 30 minutes in normothermia and atmospheric pressure (group 1), or hype

72 elation between allocation to hypothermia or normothermia and cerebral lesions was assessed by logist

73 Under normothermia and delayed whole-body cooling to 35 and 33

74 ction) followed by postexercise ischaemia in normothermia and during heat stress (increase in interna

75 In normothermia and during whole-body heating, 2 min IHG ex

76 rolongs the proinflammatory response whereas normothermia and especially febrile range temperature en

77 which was 51 mins in the control group with normothermia and FIO2 of 0.25, was more than doubled wit

78 Cooling from hyperthermia to normothermia and from normothermia to mild hypothermia i

79 In both normothermia and heat-stress conditions the following re

80 es C) and atmospheric pressure (group 2), or normothermia and high pressure (25 cm H2O) (group 3), or

81 atric hypoxic-asphyxic cardiac arrest during normothermia and hypothermia and tested novel measures o

82 ied the lower limit of autoregulation during normothermia and hypothermia in piglets resuscitated fro

83 decreased with cooling from hyperthermia to normothermia and mild hypothermia, whereas left ventricu

84 onist, BHT-933 (1.0 to 10 mug kg min) during normothermia and passive leg heating (water-perfused pan

85 ndependent association between perioperative normothermia and SSI (adjusted odds ratio, 1.05; 95% con

86 ed at two temperatures-38 degrees C (induced normothermia) and 34 degrees C (induced hypothermia)-in

87 74 +/- 5 mL at hyperthermia, 52 +/- 4 mL at normothermia, and 41 +/- 3 mL at mild hypothermia; all p

88 33 degrees C (hypothermia) or 37 degrees C (normothermia) between 1 and 24 h.

89 rtex, followed immediately by 1 hr of either normothermia (brain temperature 37 +/- 0.5 degrees C) or

90 HOE alone affords significant protection at normothermia but is not a superior alternative to CP, an

91 assigned to the following treatment groups: normothermia (cell culture media, 2 hours, 37 degrees C)

92 tes, randomized (minimum: 30 cells/group) to normothermia: (cell media for 2 hours/37 degrees C), and

93 a cohort of rats was managed with controlled normothermia (CN) by placement in a servo-controlled inc

94 ere more likely to have final intraoperative normothermia compared with controls (87.6% vs. 77.8%, P

95 h and then gradually rewarmed or treated at normothermia, depending upon their initial treatment ass

96 ic hypothermia, as compared with therapeutic normothermia, did not confer a significant benefit in su

97 ic hypothermia, as compared with therapeutic normothermia, did not confer a significant benefit in su

98 Reestablishing normothermia during anesthesia completely rescued tau ph

99 to monitor core temperature and to maintain normothermia during general and neuraxial anaesthesia.

100 Intracellular free Ca2+ increased from normothermia during hyperkalemic cardioplegia in control

101 grees C, 59% vs. 3%, p < .001), and attained normothermia faster than the SubZero group median (2.4 v

102 have made eliminating fever and maintaining normothermia feasible.

103 or sham surgery and recovered for 2 hrs with normothermia followed by 4 hrs of either moderate hypoth

104 l hearts were then made globally ischemic at normothermia for 30 minutes followed by 2 hours of normo

105 rial compared intraoperative hypothermia and normothermia for potential neuroprotection during neurov

106 iant prophylactic antibiotics, postoperative normothermia, glucose control, and oral antibiotics.

107 utcome between the hypothermia group and the normothermia group (20% vs. 12%; relative likelihood, 1.

108 cantly between the hypothermia group and the normothermia group (36% [48 of 133 patients] and 39% [48

109 112 recipients of kidneys from donors in the normothermia group (39%) (odds ratio, 0.62; 95% confiden

110 cantly between the hypothermia group and the normothermia group (49% [81 of 166 patients] and 46% [74

111 common in the hypothermia group than in the normothermia group (5 percent vs. 3 percent, P=0.05).

112 as compared with 314 of 501 patients in the normothermia group (66 percent vs. 63 percent; odds rati

113 only for the histological score compared to normothermia group (IFD index, P<0.05).

114 rmia group and 36.6 +/- 0.5 degrees C in the normothermia group (P < 0.001) Surgical-wound infections

115 also significantly improved compared to the normothermia group (P < 0.05).

116 histology) and higher blood glucose than the normothermia group (p <.05).

117 the hypothermia group and 27 percent in the normothermia group (P=0.79).

118 in the hypothermia group and 25 of 56 in the normothermia group (relative risk [RR] 1.08, 95% CI 0.76

119 hermia group died compared with eight in the normothermia group (RR 1.30, 95% CI 0.58-2.52; p=0.52).

120 None of the 8 animals in the normothermia group achieved resumption of spontaneous ci

121 thermia group and 38 percent of those in the normothermia group had good outcomes (moderate, mild, or

122 ypothermia group and seven of 15 rats in the normothermia group survived to 24 hrs (p <.05).

123 s (52 in the hypothermia group and 45 in the normothermia group) did not meet any of the second set o

124 ypothermia group) or additional warming (the normothermia group).

125 (180 in the hypothermia group and 190 in the normothermia group).

126 mia group and 287 kidneys from donors in the normothermia group).

127 outcome by GOS-extended paediatrics; in the normothermia group, 16 [42%] patients had a poor outcome

128 hypothermia group and 4.1+/-1.2 hours in the normothermia group, and the mean time from injury to the

129 y, 4-6) and three (13%) died, whereas in the normothermia group, three (12%) had a bad outcome and on

130 nt between survivors and nonsurvivors in the normothermia group.

131 p had high intracranial pressure than in the normothermia group.

132 with complications than the patients in the normothermia group.

133 ): 39 in the hypothermia group and 38 in the normothermia group.

134 rmia group vs two [5%] of 38 patients in the normothermia group; p=0.15).

135 (38% in the hypothermia group vs. 29% in the normothermia group; relative likelihood, 1.29; 95% CI, 0

136 (Group ii) sham-33 degrees C; (Group iii) HI-normothermia; (Group iv) HI-35 degrees C; and (Group v)

137 2-hour survival than delayed hypothermia and normothermia groups (6/10 versus 1/10 and 1/10 survivors

138 ees C and 36.8 degrees C for hypothermia and normothermia groups.

139 f injury were similar in the hypothermia and normothermia groups.

140 auditory discrimination from hypothermia to normothermia has a high predictive value for awakening.

141 Maintaining perioperative normothermia has been shown to decrease the rate of surg

142 ation is lacking, and an exact definition of normothermia has not been described.

143 diated increase in cardiac index observed at normothermia, high-dose dopamine at 25 degrees C left ca

144 Compared with normothermia, hypothermia at 35 degrees C led to 25 and

145 ere randomly assigned to one of five groups (normothermia, hypothermia, cyclopentyladenosine (CPA), t

146 In normothermia, IHG exercise increased sweat rate at the n

147 Restoring normothermia improved sepsis survival from 42% to 60% (p

148 f cooling, rewarming, or within 15 hrs after normothermia in 57% (28 of 49) of cases.

149 ared the effects of moderate hypothermia and normothermia in 82 patients with severe closed head inju

150 s a modern technique that preserves lungs on normothermia in a metabolically active state.

151 and 180-day survival compared to spontaneous normothermia in cardiac-arrest patients.

152 eater adiposity, thereby helping to maintain normothermia in obesity.

153 hypothermia (32 degrees C-33 degrees C) vs. normothermia in patients treated in a single center invo

154 ing the effects of hypothermia with those of normothermia in patients with acute brain injury.

155 ltaCVC was observed between hyperthermia and normothermia in the control site (Site A).

156 rative hypothermia and the group assigned to normothermia in the duration of stay in the intensive ca

157 Mild hypothermia, as compared with normothermia, in organ donors after declaration of death

158 s: In control group 1 (n = 7), CPCR was with normothermia; in group 2 (n = 6, 1 of 7 excluded), with

159 Dopamine half-time was 5.4 +/- 0.7 min at normothermia, increased to 11.6 +/- 0.8 min at 25 degree

160 , mild hypothermia during UHS, compared with normothermia, increases blood pressure, survival time an

161 Abrupt temperature shift from hypothermia to normothermia incurred on reperfusion of organ grafts has

162 Maintaining normothermia intraoperatively is likely to decrease the

163 with hypothermia (IQ = 0.74), compared with normothermia (IQ = 0.60) and hyperthermia (IQ = 0.56) (p

164 Although intraoperative normothermia is an important quality performance measure

165 ac surgery, the perioperative maintenance of normothermia is associated with a reduced incidence of m

166 there is limited evidence that perioperative normothermia is associated with lower rates of SSI.

167 r-fold compared to the same infusion rate at normothermia, leading to increased systemic vascular res

168 Thus, the effects of spontaneous normothermia (<37.5 degrees C) compared with mild therap

169 armed by 0.5-1.0 degrees C every 12-24 h) or normothermia (maintained at 36.5-37.5 degrees C).

170 videomicroscopy under three conditions: (1) normothermia, maintained in cell medium (37 degrees C) f

171 reporting measures focusing on perioperative normothermia may be of limited value in preventing SSI a

172 osed to currently mandated publicly reported normothermia measures.

173 Compared with normothermia, mild hypothermia increased the survival ti

174 ditive to CP provides significant benefit at normothermia, moderate hypothermia, and severe hypotherm

175 Newborn piglets were randomized to: (i) HI-normothermia (n=12), (ii) HI-35 degrees C (n=7), and (ii

176 , 23.0+/-0.6 kg) were divided into 4 groups: normothermia (n=8), mild hypothermia (35 degrees C) (n=8

177 ical care strategies directed at maintaining normothermia, normoglycemia, and prevention of anemia ma

178 During normothermia, NP decreased CVC by 0.032 +/- 0.007 arbitr

179 tes after birth, (2) Delayed intubation, (3) Normothermia on Neonatal Intensive Care Unit Admission,

180 d at 37 degrees C throughout the experiment (normothermia) or reduced to 33 degrees C between 1 and 2

181 s C (mild hypothermia), 35.5-36.5 degrees C (normothermia), or 37.5-38.5 degrees C (mild hyperthermia

182 lower in all treatment groups compared with normothermia (p < 0.01) (although >40mmHg); the combined

183 B and Site C during hyperthermia compared to normothermia (P < 0.05).

184 ned to hypothermia than in those assigned to normothermia (P = 0.002), and the duration of hospitaliz

185 incomplete recovery of brainstem reflexes in normothermia (p = 0.013), and neuron-specific enolase hi

186 CA prolonged T50 by approximately 19% from normothermia (P<0.05) and was further prolonged with ET-

187 A reduced PERSHORT by approximately 35% from normothermia (P<0.05), which was further reduced with ET

188 =-4.69+/-0.44; r(2)=0.84+/-0.03) compared to normothermia (P<0.05), while the relationship between ar

189 rmia group (6 of 8 hypothermia versus 1 of 8 normothermia; P=0.04).

190 (maximal decreases in FVC during heating vs. normothermia: PE: 7.8 +/- 1.1 vs. 2.8 +/- 0.5 ml min mmH

191 , indicating a role for FGF21 in maintaining normothermia, possibly via activation of BAT.

192 lactic intravenous antibiotic, postoperative normothermia, postoperative day 1 glucose control, and o

193 correlated with the reduction in PCWP during normothermia (r = 0.93), skin-surface cooling (r = 0.91)

194 urgical Care Improvement Project must report normothermia rates during major surgery.

195 led conditions of normoxia, normocarbia, and normothermia, rats were subjected to 2 hrs of MCAO.

196 ether, these results could be interpreted in normothermia septic rats as an adaptive mechanism that c

197 ucose target levels less than 200 mg/dL, and normothermia should be maintained in all patients.

198 Our results suggest that intraoperative normothermia should be strictly maintained in patients u

199 -pressure (LBNP) of 0, 15 and 30 mmHg during normothermia, skin-surface cooling (decrease in mean ski

200 1 +/- 10, 131 +/- 7 ml prior to LBNP, during normothermia, skin-surface cooling, and whole-body heati

201 led conditions of normoxia, normocarbia, and normothermia, spontaneously breathing, halothane-anesthe

202 led conditions of normoxia, normocarbia, and normothermia, spontaneously breathing, halothane-anesthe

203 in ventricular filling pressure, compared to normothermia, suggests that the heart is operating on a

204 es C for 12 h) and the other half (n = 7) to normothermia (T = 37 degrees C).

205 th the use of surface cooling techniques) or normothermia (target temperature, 36.5 degrees C).

206 temperature, 33.0 degrees C) or therapeutic normothermia (target temperature, 36.8 degrees C).

207 temperature, 33.0 degrees C) or therapeutic normothermia (target temperature, 36.8 degrees C).

208 PB has a positive slope that is greater with normothermia than hypothermia.

209 Upon return to normothermia, the vascular particles dissolve into the p

210 To maintain normothermia, therefore, obese individuals must increase

211 er in patients randomized to hypothermia vs. normothermia, this difference was not statistically sign

212 SCIP adherence ranged from 75% for normothermia to 99% for hair removal and all significant

213 The control group had strict normothermia to a temperature of 36-37 degrees C for 72

214 g from hyperthermia to normothermia and from normothermia to mild hypothermia increased left ventricu

215 yperthermia to normothermia: -28% +/- 3% and normothermia to mild hypothermia: -20% +/- 5%) was of co

216 pectively in 10 hypothermia-treated and nine normothermia-treated children who were randomized to 48

217 ation in rats and did not affect recovery of normothermia-treated rats.

218 ature levels (38 degrees C [100.4 degrees F; normothermia] vs. 34 degrees C [93.2 degrees F; mild hyp

219 ree rectal temperature levels (38 degrees C [normothermia] vs. 34 degrees C [mild hypothermia] vs. 30

220 Normothermia was maintained.

221 04), indicating a 55% reduction in risk when normothermia was maintained.

222 auditory discrimination from hypothermia to normothermia was observed for 33 out of 94 patients.

223 Normothermia was present in 6,133 (55%) and mixed fever/

224 Anesthesia, fluid balance, and normothermia were maintained.

225 P = 0.015); rates of immediate postoperative normothermia were similar (70.6% vs. 65.3%, respectively

226 a lower-body negative pressure (LBNP) during normothermia, whole-body heating (increase in blood temp

227 day having a unique experimental condition: normothermia, whole-body heating, and whole-body heating

228 hrs, and perioperative warming reestablished normothermia within 1 hr.