ライフサイエンスコーパス: notochordal

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1 l plate and at lower levels in the posterior notochordal and neural regions during convergent extensi

2 gh cell motility continues, and the anterior notochordal and somitic mesoderm differentiate in the pr

3 the pre-involution marginal zone, posterior notochordal and somitic mesoderm do not differentiate.

4 Humans and other species in which notochordal cells (NCs) disappear to be replaced by chon

5 recordings show that presumptive somitic and notochordal cells move out of the roof of the gastrocoel

6 and do not undergo CE like the Gsc-negative notochordal cells, which subsequently emerge from the or

7 This suggests the possibility of notochordal defects.

8 lignant, often incurable bone tumour showing notochordal differentiation.

9 articipate in this process by modulating the notochordal expression of HNF-3 beta.

10 bsence of DLHPs at high spinal levels, where notochordal expression of Shh is strong.

11 hich seems likely to be regulated by another notochordal factor.

12 Finally, our results demonstrate that the notochordal inducer also induces the reconstituted Hense

13 a key mediator of FGF signaling in trunk non-notochordal mesoderm, since spadetail expression is regu

14 ochord, although adult NP lacks identifiable notochordal (NC) cells.

15 nsgene can be reliably restricted to muscle, notochordal, or neuronal tissues.

16 ecular expression pattern derived from their notochordal origin, and reside in N-cadherin (CDH2) posi

17 hree cases of chordoma, a cancer of presumed notochordal origin.

18 tial roles in morphogenesis of the posterior notochordal plate (the node) and the midline.

19 de in mouse, Kupffer's vesicle in zebrafish, notochordal plate in rabbit and gastrocoel roof plate in

20 otochord precursors from the tail bud to the notochordal plate seems impaired, whereas notochord form

21 d-type cells in the midline neural plate and notochordal plate, consistent with a cell-autonomous dis

22 hat Cripto is essential for formation of the notochordal plate, prechordal mesoderm and foregut endod

23 rior-most region of the notochord and in the notochordal plate.

24 e streak, the head process, and the node and notochordal plate.

25 nnexin43.4 expression remained absent in the notochordal precursor cells and was lost in the tail bud

26 Despite lacking normal notochordal precursor cells, the notochord still forms i

27 Chordoma is a rare tumor originating from notochordal remnants that is usually diagnosed during mi

28 Notochordal signaling induces midline bending and simult

29 Consistent with the disorganization of notochordal signals in the alpha5-null embryos, reduced

30 urces of the missing laminin chain, although notochordal sources are also sufficient for rescue.

31 -null embryos due to (1) degeneration of the notochordal tissue structure, and (2) non-maintenance of

32 grafted cells from each region give rise to notochordal tissue.

33 hord-inducing signals and differentiate into notochordal tissue.

34 but, in the absence of interactions with non-notochordal tissues, they neither invaginate nor converg

35 We reveal somatic duplications of the notochordal transcription factor brachyury (T) in up to

36 doma in 104 cases, revealing duplications in notochordal transcription factor brachyury (T), PI3K sig

37 that the spadetail gene is required for non-notochordal trunk mesoderm formation; spadetail mutant e

38 d tail, the pathways activated by FGF in non-notochordal trunk mesoderm have been uncertain.

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