ライフサイエンスコーパス: novelty

1 rn to discriminate beneficial from dangerous novelty.

2 suggests that this capacity is a salamander novelty.

3 e contraction, niche intermediacy, and niche novelty.

4 an important mechanism for adding to genomic novelty.

5 mping genes' as a source of major phenotypic novelty.

6 ikeness, structural diversity and scientific novelty.

7 e capacity for the exploration of phenotypic novelty.

8 regulatory networks can generate phenotypic novelty.

9 flammation impairs motivational responses to novelty.

10 d have the potential to produce evolutionary novelty.

11 gm for sociability and preference for social novelty.

12 selected based on biological and/or chemical novelty.

13 t was proportional to the stimulus degree of novelty.

14 significantly impaired preference for social novelty.

15 ory network in the origin of an evolutionary novelty.

16 lammation inhibit the motivation to seek out novelty.

17 erament characterized by strong reactions to novelty.

18 ome suggest a potential for enduring genomic novelty.

19 to sociability versus preference for social novelty.

20 evolutionary mechanisms leading to metabolic novelty.

21 orted the evolution of a major morphological novelty.

22 ect on sociability and preference for social novelty.

23 new bibliometric statistics: Importance and Novelty.

24 ants, followed by filtering to confirm their novelty.

25 ntributor to genome evolution and phenotypic novelty.

26 lds, two major lophotrochozoan morphological novelties.

27 tend to be contemporaneous with evolutionary novelties.

28 ral attention network's role in attention to novelty, a key feature of behavioral inhibition.

29 Emergence of novelty accelerated during the past 1000 years.

30 idespread hypothesis, based on findings that novelty activates reward-related structures, is that all

31 Here we show that, contrary to this idea, novelty affects visual salience in the monkey lateral in

32 s rather than the origination of morphologic novelty alone.

33 dramatically derived bodies and a remarkable novelty among vertebrates, the male brood pouch.

34 see more of the world and cultures, to seek novelty and adventure); (b) work-related factors (better

35 use social cues equally around all types of novelty and at all times of year.

36 in 2010 or after, which give an idea of the novelty and current interest in this area.

37 ral habituation, enables organisms to detect novelty and devote cognition to important elements of th

38 t of selected studies was assembled based on novelty and direct relevance to the primary focus of thi

39 With its novelty and enabling features including downscaled analy

40 ion of individual items and objects, but how novelty and familiarity are encoded and transmitted in t

41 Significance statement: Recognition of novelty and familiarity are important for learning, memo

42 Perirhinal neurons respond to novelty and familiarity by changing firing rates, but re

43 normal brain, perirhinal neurons respond to novelty and familiarity by increasing or decreasing firi

44 ined the neural and behavioral correlates of novelty and familiarity in the olfactory system of Droso

45 depend critically on the balance between the novelty and familiarity of the microbial communities the

46 e, which is in part governed by evolutionary novelty and functional specialization.

47 Allopolyploidy often triggers phenotypic novelty and gene expression remolding in the resulting p

48 novelties, thus the primary questions about novelty and innovation focus on their ecological and evo

49 Morphological novelty and innovation has been a recurrent theme.

50 Consequently a broader view of novelty and innovation is required.

51 theory made three claims about evolutionary novelty and innovation: first, that all diversifications

52 This has been proposed as a salamander novelty and its mechanistic basis is unknown.

53 ertion near a gene can contribute to genetic novelty and phenotypic plasticity.

54 Because of RodZ's novelty and potential usefulness for understanding TM he

55 n this regard, the co-occurrence of striatal novelty and retrieval success effects in independent stu

56 led in a watermaze that placed the impact of novelty and sleep in opposition.

57 to reservoirs' chemical potentials enjoy the novelty and the potential.

58 ng in love--that are awakened by openness to novelty and to the Other.

59 iew article aims to strike a balance between novelty and validity by focusing on recent large sample-

60 task engagement: 1) task difficulty, 2) task novelty, and 3) aging effects.

61 d metagenomic data in detection of microbial novelty, and highlights the extraordinary diversity of m

62 l evolution of beetle horns, an evolutionary novelty, and horn polyphenisms, a highly derived form of

63 nfluences motor behavior, signals reward and novelty, and is an essential component of the basal gang

64 deleterious rearrangements, but also genetic novelty, and many questions regarding its genesis, fate

65 nsights into the emergence of plant chemical novelty, and offers a template for investigating the 30

66 icting how social information is used around novelty, and potentially indicates the conditions that f

67 ired motor coordination, altered response to novelty, and sensory processing deficits.

68 he generation of biodiversity and biological novelty, and therefore understanding the factors that dr

69 (3'UTR), and is significantly associated to novelty- and reward-related behavioral traits in humans

70 Right after exposure to the novelty, animals were given bilateral intrahippocampal i

71 lated structures, is that all the effects of novelty are explained in terms of reward.

72 to gain information) and neophobia (avoiding novelty) are considered independent traits shaped by the

73 ty foundation on which complex immunological novelties arose.

74 hod a powerful alternative, practicality and novelty aside, to commonly used organic halides as count

75 retation, antibody optimization, and epitope novelty assessment.

76 neurons mimics the novelty effect, and this novelty-associated memory enhancement is unaffected by v

77 highlight occasional bursts of morphological novelty at certain stages particularly close to the orig

78 d the likelihood that an animal would choose novelty at different stages of its training and found ev

79 by recommending that our current emphasis on novelty be replaced by a renewed emphasis on predictive

80 The suggested method presents novelty both in group-decision-making and in environment

81 nomes, as mutagens and as sources of genetic novelty (both coding and regulatory) to be acted upon by

82 ained in the hippocampus in association with novelty but in the cortex in association with sleep.

83 d the role of gene duplication in functional novelty, but its potential has not been fully realized.

84 Gene and genome duplication fosters genetic novelty, but redundant gene copies would undergo mutatio

85 associated with memory generation supported novelty concealment.

86 I conclude that placing too much value on novelty could have counterproductive effects on both the

87 Recognition of novelty depends upon intact perirhinal (pRh) cortex func

88 tions with CellCognition Explorer, a generic novelty detection and deep learning framework.

89 (2) Novelty detection is when a second group of interneurons

90 cific adaptation to the masker spectrum and "novelty detection" to the 2 kHz band present only in the

91 he hippocampal formation during exploration, novelty detection, and memory encoding.

92 The perirhinal cortex is critical for novelty detection, and perirhinal metabotropic glutamate

93 types of information processing: automatic (novelty detection, attention biases to threat, and incen

94 potential, reflecting two steps of auditory novelty detection, have been inconsistently observed in

95 l state, (iii) posture recognition, and (iv) novelty detection--is able to learn from an interactive

96 and placebo, consistent with intact central novelty detection.

97 nk between stimulus probability-based change/novelty detectors operating at lower levels of the audit

98 nk between stimulus probability-based change/novelty detectors operating at lower levels of the audit

99 The evolutionary novelties developed by these rodents were surveyed in pa

100 cal cultural landscapes experienced a faster novelty development due to the contribution from anthrop

101 in response to amphetamine (Amph) and social novelty discrimination (SND) deficits.

102 virus lineage but have also established many novelties due to their symbiotic lifestyle.

103 The results attest to the generality of the novelty effect on fear extinction, suggest that it relie

104 of locus coeruleus TH(+) neurons mimics the novelty effect, and this novelty-associated memory enhan

105 he neurons mediating this dopamine-dependent novelty effect, previously thought to originate exclusiv

106 e identification of causal variants based on novelty, effect and annotation information.

107 The novelty, efficiency, versatility, and sustainability of

108 In particular, memory retrieval and novelty encoding were considered in independent studies,

109 reveal a spatiotemporal dissociation between novelty/encoding and familiarity/retrieval signatures, a

110 As a novelty, EPA, DHA or fish oil (FO) were incorporated as

111 The prolongation of auditory obligatory and novelty ERPs in WS patients indicates a severe failure o

112 our and provide insights into how phenotypic novelty evolves.

113 This MCH cell activity correlates with novelty exploration, is inhibited by stress and is inver

114 e developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association between p

115 , we investigate how different approaches to novelty (fast or slow) determine the time at which explo

116 hollow, osseous nasal crests: a craniofacial novelty for mammals that is remarkably comparable to the

117 Although novelty generally increases as a function of time, clima

118 partite regulatory system is an evolutionary novelty generated by combining ancient long-range regula

119 arly-onset seasons associated with antigenic novelty had particularly localized modes of spread, sugg

120 , how the average natural product structural novelty has changed as a function of time, whether explo

121 support both hybrid bridge and evolutionary novelty hypotheses.

122 MAGNA++ introduces several novelties: (i) it simultaneously maximizes any one of th

123 In this review, the latest novelties in development and application of FRET nanosen

124 Extreme novelties in the shape and size of paired fins are exemp

125 There are multiple novelties in these two platforms that have increased the

126 Dopamine neurons are thought to encode novelty in addition to reward prediction error (the disc

127 The mesoderm is a key novelty in animal evolution, although we understand litt

128 ce between beak and braincase may be the key novelty in classic passerine adaptive radiations.

129 We reconstruct the emergence of novelty in Europe for a set of baseline conditions over

130 in complex populations is key to discovering novelty in multidimensional single-cell experiments.

131 plants (AT2) is stable but they showed clear novelty in multiple morphological traits which might hav

132 major force contributing to the emergence of novelty in nature is the presence of cooperative interac

133 become fixed in populations, contributing to novelty in older polyploid lineages.

134 ting to the evolution of gene innovation and novelty in plant genomes.

135 ronment - dolphin gums - uncovers surprising novelty in the bacterial tree of life, underscoring the

136 This novelty in the protocol resulted in obtaining a signific

137 Besides, the novelty in this research also lies in the simultaneously

138 reveals numerous deuterostome-specific gene novelties, including genes found in deuterostomes and ma

139 The novelty increased hippocampal dopamine levels and facili

140 oxetine and citalopram administration in the novelty induced hypophagia test (NIH) and fail to exhibi

141 us to directly test the relationship between novelty-induced acetylcholine release and later contextu

142 bsequent pairing with shock, suggesting that novelty-induced acetylcholine release primes future cont

143 Casp3(-/-) mice was correlated with enhanced novelty-induced activity in the dentate gyrus, which may

144 termates, female DISC1(D453G) mice exhibited novelty-induced hyperlocomotion, an anxiogenic profile i

145 behaviors, including cognition, anxiety, and novelty-induced hyperlocomotion, as well as PVB loss in

146 ronic mild stress, chronic forced swim test, novelty-induced hypophagia (NIH), novelty-suppressed fee

147 l testing measured anxiety levels, using the Novelty-Induced Hypophagia test, and cognition, using a

148 hdrawal-induced anxiety-like behavior in the Novelty-Induced Hypophagia test.

149 ics associated with "temperament," including novelty-induced locomotion and impulsivity.

150 sation seekers (HR) on the basis of elevated novelty-induced locomotor reactivity, high anxious rats

151 NRG2 KOs exhibit hyperactivity in a novelty-induced open field, deficits in prepulse inhibit

152 iability while leaving preference for social novelty intact.

153 Establishing a timeline for the evolution of novelties is a common, unifying goal at the intersection

154 One of the novelties is the generality of the model in each layer.

155 The emergence of novelty is baseline specific and, during the early-Holoc

156 To understand how this novelty is generated, we investigated the evolution of t

157 While this protocol uses watermarking, its novelty is in use of more complex cryptographic techniqu

158 ties are not stable over time and biological novelty is predicted to emerge due to climate change, th

159 fy deeply conserved similarities, as well as novelties key to the biology of these organisms.

160 Further, the method's novelty lies in the manner in which isofunctional groups

161 eus is especially sensitive to environmental novelty, locus coeruleus TH(+) neurons project more prof

162 ts select exploratory actions according to a novelty management framework and suggests a plausible me

163 However, the rate at which this novelty may arise over longer time periods has so far re

164 latory genes and highlight how morphological novelty may originate through the co-option of networks

165 rstand how important an explicit emphasis on novelty might be for scientific progress.

166 ogy of science to anticipate how emphasizing novelty might impact the structure and function of the s

167 cal analyses, will help to target functional novelty more efficiently.

168 incentivise quantity more than quality, and novelty more than reliability.

169 n ways that generate many classes of genomic novelties; natural genetic engineering functions are reg

170 idered in independent studies, implying that novelty (new > old) and retrieval success (old > new) ef

171 S analyses tools, we demonstrate some of the novelties obtained by the approach implemented in HiBS a

172 s (age range = 3-9 months) using an auditory novelty oddball paradigm.

173 The chief novelties of our method are that it is able to infer rat

174 The major novelty of BOCTOPUS2 is the use of the dyad-repeat patte

175 The structural novelty of bottromycin stems from its unprecedented macr

176 The breadth and evolutionary novelty of candidate virulence factors that we discover

177 observations give insight into the chemical novelty of drugs and potentially efficient ways to asses

178 Due to the novelty of e-cigarettes (e-cigs) and e-cigarette liquids

179 We show that the extent of novelty of expressed transcripts decreases significantly

180 r this role of Toll genes is an evolutionary novelty of flies or a general mechanism of embryonic mor

181 ation tools can be explained by the relative novelty of imaging techniques such as interferometric ph

182 The novelty of JDINAC lies in its potential to capture non-l

183 The novelty of our approach is to design an integrated proce

184 The novelty of our approach lies in (1) representing cell-sc

185 The key novelty of our approach lies in specifying latent stocha

186 The novelty of our approach resides in the combination of th

187 The novelty of our method is that the contribution of each d

188 The main novelty of our study is the combination of time-series s

189 Here we develop a framework to test the novelty of population-level findings against simpler fea

190 us exemplifies the plasticity, dynamics, and novelty of regulatory networks mediated by WGD.

191 The novelty of Strawberry is that the two modules use differ

192 Due to the relative novelty of the field, the published data is sometimes co

193 The novelty of the instrument lies in its ability to monitor

194 xpression in cancer cells and highlights the novelty of the mda-7/IL-24-miR-221-beclin-1 loop in medi

195 The novelty of the method lies on the unique determination o

196 stics, which is a testament to the power and novelty of the model.

197 modulating the IL-12/IL-12R pathway and the novelty of the OT-II.Ncf1(m1J) mouse model to determine

198 attract widespread attention due to both the novelty of the phenomena observed and the ability to rel

199 The novelty of the present study is the determination of mit

200 The novelty of the procedure is the production of glass bead

201 The novelty of the proposed optical sensor resides in its si

202 perception and concern that the fundamental novelty of these discoveries is decreasing relative to p

203 The novelty of this finding will be investigated in longitud

204 The novelty of this study consists in the combination of the

205 The particular novelty of this study lies in the direct correlation of

206 The novelty of this study lies on both the development of a

207 The novelty of this study was based on the application of li

208 The novelty of this system is a scintillating balloon in the

209 The novelty of this work arises from the new synthesis metho

210 The novelty of this work is on the investigation of directly

211 The novelty of this work is that we develop the pathway as w

212 The novelty of this work is the first incorporation of NKA i

213 The novelty of this work lies in its ability to identify ind

214 The variation and novelty of various desirable traits seen in these previo

215 ehavioral results regarding the influence of novelty on inhibitory avoidance memory in rats.

216 d mice to exhibit behaviours associated with novelty or anxiety.

217 plicating the claustrum in detecting sensory novelty or in amplifying correlated cortical inputs to c

218 y cortices without the confounds of stimulus novelty or repetition suppression, we used a cross-modal

219 and how dopaminergic release in response to novelty or reward can modulate which cell assemblies are

220 effect of increases in firing could reflect novelty or salience, variables also correlated with dopa

221 nd interference associated with postencoding novelty or sleep.

222 ta suggest that high locomotor reactivity to novelty, or sensation seeking, by predisposing to an inc

223 ciated with increased disparity, morphologic novelty, or the radiation of a single subclade.

224 By quantifying the dynamics of correlated novelties, our results provide a starting point for a de

225 ation is a primary means to generate genomic novelties, playing an essential role in speciation and a

226 a combination of anatomical and biochemical novelties predicted to increase productivity in warm and

227 Novelty preference (NP) is an evolutionarily conserved,

228 r baseline conditions (eg, increased spatial novelty preference in COMT-Met mice vs wild-type mice).

229 we show how a recently derived morphological novelty present in the genitalia of D. melanogaster empl

230 ransmission and its involvement during taste novelty processing and familiar taste memory retrieval.

231 hypothesized roles of SN and hippocampus in novelty processing.

232 owleys sociability and preference for social novelty protocol.

233 established as playing an important role in novelty related modulation of hippocampal memory.

234 ndingly, inflammation also markedly impaired novelty-related functional coupling between the SN and h

235 se, indicating that the offset response is a novelty-related signature.

236 obligatory components (P150, N250, P350) and novelty response components (P300, Nc) were recordable d

237 Both experiments showed also the novelty responses of dopamine neurones that decreased as

238 tion with familiar stimuli without affecting novelty responses, whereas photoactivation of the same n

239 Different acute challenges, including novelty, restraint, and FS stress, produced distinct glu

240 that the vertebrate head is an evolutionary novelty resulting from the emergence of neural crest and

241 Ts) and completely novel transcripts (CNTs) (novelty score >/= 70%) revealed that the PNTs are both h

242 ment; harm avoidance (HA), persistence (PS), novelty seeking (NS), reward dependence (RD), and three

243 sencephalic circuits possibly contributes to novelty seeking and positive reinforcement traits.

244 pacts behavioral domains related to fear and novelty seeking and that these alterations might be rela

245 anisms through which inflammation constrains novelty seeking are poorly understood.

246 ls through unique IPN circuitry that opposes novelty seeking to control NP.

247 ild-type littermates, with typical high risk/novelty seeking, increased peer interaction, enhanced im

248 have severe clinical repercussions including novelty seeking, response disinhibition, aggression, and

249 strong determinant of the temperament trait novelty seeking.

250 tween anterior cingulate cortex activity and novelty seeking.

251 re we use a longitudinal design to track 144 novelty-seeking adolescents at age 14 and 16 to determin

252 d neural responses to anticipated rewards in novelty-seeking adolescents may increase vulnerability t

253 nced sensorimotor gating deficits, increased novelty-seeking and reduced fear extinction.

254 ychiatric disorders associated with abnormal novelty-seeking behaviors.

255 interaction in the NAcSh directly influences novelty-seeking exploratory behavior and facilitates sel

256 High novelty-seeking temperament was robustly associated with

257 Novelty-seeking tendencies in adolescents may promote in

258 There was an association of rs2235749 with novelty-seeking trait and a strong genotype-dose associa

259 udy, in providing a mechanistic link between novelty signals and the underlying representations, cons

260 her, these results demonstrate that dopamine novelty signals are localized in TS along with general s

261 y the IPN depends on familiarity signals and novelty signals arising from excitatory habenula and dop

262 uced blunting of SN responses to hippocampal novelty signals may represent a plausible mechanism thro

263 Further, we provide evidence that novelty signals within the DG are stimulus specific rath

264 ying representations from the observation of novelty signals.

265 ergent evolution of these complex functional novelties speaks to the persistence and potency of the s

266 sion test (TST), forced swimming test (FST), novelty suppressed feeding (NSF) test, and open field te

267 exercise reduced the latency to feed in the novelty suppressed feeding and the immobility time in th

268 ss-induced behavior in the forced swim test, novelty suppressed feeding paradigm, and the sucrose spl

269 -DOR mice reached the food more rapidly in a novelty suppressed feeding task, despite their lower mot

270 s, as well as reduced latency to feed in the novelty suppressed feeding test.

271 WT in forced swimming, tail suspension, and novelty suppressed feeding tests, typical of depressive-

272 using the forced swim, tail suspension, and novelty suppressed feeding tests.

273 Finally, c-fos protein staining after novelty suppressed feeding was strongly reduced in amygd

274 anxiety (elevated plus maze, marble burying, novelty suppressed feeding).

275 related behaviors were evaluated through the novelty suppressed feeding, marble burying, splash, and

276 tic ACC stimulation and were evaluated using novelty suppressed feeding, splash, and forced swim test

277 swim test, novelty-induced hypophagia (NIH), novelty-suppressed feeding (NSF), social defeat stress,

278 even 35 days after ethanol withdrawal in the novelty-suppressed feeding test (NSFT).

279 using the open-field, elevated plus maze and novelty-suppressed feeding tests.

280 on of regulatory strategies and evolutionary novelties that led to new plant forms.

281 trate the early acquisition of morphological novelties that were later convergently evolved by post-T

282 The neural crest is an evolutionary novelty that fostered the emergence of vertebrate anatom

283 A key novelty that makes the presented terahertz detector supe

284 ntified others - most notably, environmental novelty - that merit further investigation because littl

285 Accurately dating GRN novelties, thereby establishing a timeline for GRN evolu

286 Along with the structural novelty, these hollow cages show highly selective adsorp

287 As a novelty, they show that the ensuing illusory causal bind

288 ther than by the supply of new morphological novelties, thus the primary questions about novelty and

289 rget - altering an individual's mood or task novelty - to improve learning.

290 Ultrasound irradiation (37kHz) was novelty used for performing the Mn-doped ZnS QDs synthes

291 ive of both number of compounds and compound novelty using a dataset of all published microbial and m

292 ormal bilateral reactivity of SN to stimulus novelty was significantly attenuated following inflammat

293 igural processing, regardless of an object's novelty, was strongly predicted by alERC volume, but not

294 Of particular novelty, we identified the PRC2-associated protein, ASXL

295 Hippocampal memory traces followed by novelty were more dominant by default but liable to inte

296 e whether there are risks to overemphasizing novelty when deciding what constitutes good science.

297 osive seed dispersal that links evolutionary novelty with complex trait innovation.

298 d to a non-linear post-glacial trajectory of novelty with jumps corresponding to periods of rapid cha

299 ennal lobe circuit depending on its relative novelty with respect to a preceding stimulus.

300 To illustrate novelty within the dataset, we surveyed the genomic land