ライフサイエンスコーパス: nub

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1 Here, we show that NUBBIN (NUB), a gene closely related to JAG, is responsible for

2 Overall, we propose that nub acts downstream of Notch on the distal part of insec

3 nd gynoecium development, where we find that NUB acts redundantly with JAG to promote the growth of t

4 asciatus (milkweed bug), showed that nubbin (nub) affects antenna morphogenesis, labial patterning, t

5 JAG and NUB also act redundantly to promote the differentiation

6 lso show that despite shifting position, the Nub and Tsh domain boundaries, like compartment boundari

7 Unlike classical compartments, the Nub and Tsh domains do not define absolute lineage restr

8 s of the wing and mammalian rhombomeres, the Nub and Tsh domains share some of the attributes of clas

9 Once established, the Nub and Tsh domains, and the intervening region in which

10 due to regulation by Wingless signaling, the Nub and Tsh expression boundaries shift during developme

11 omains of two transcription factors, Nubbin (Nub) and Teashirt (Tsh), present in distal and proximal

12 rane spanning macromolecules linked to these nubs are also attached to the AZM macromolecules.

13 e is nearly the same vesicle to vesicle, and nubs, at their sites of connection to the vesicle membra

14 ibia), and in this species we also show that nub expression in the legs is regulated by Notch signali

15 of-function experiments showing that ectopic NUB expression is sufficient to drive the proliferation

16 Similarly, our re-analysis of nub function in Drosophila reveals that legs lack all tr

17 irst functional evidence defining a role for nub in leg segmentation and highlight the varying degree

18 Unlike JAG, NUB is exclusively expressed in leaves, stamens and carp

19 ends into all cell layers of lateral organs, NUB is restricted to the interior adaxial side.

20 The nub of the problem lies in the inherent variability of t

21 The connection sites of most nubs on the membrane of docked vesicles are paired with

22 In addition, we find that the distal factor Nub represses the ligand unpaired as well as Stat92E act

23 While both Acheta and Periplaneta nub-RNAi first nymphs develop crooked antennae, no visib

24 of these two segments and creates a chimeric nub-RNAi tibia-tarsus that retains a tibial identity in

25 e density at veil margins, and protrusion of nubs that transform into filopodia.

26 In cells with two short branches or nubs, the proteins oscillated symmetrically from one end

27 2) "axial" filaments connect focal rings to nub tips, thereby organizing filament bundling and ensur

28 cromolecules attached by narrow projections, nubs, to the vesicle membrane at approximately 25 sites.

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