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1 DAF-16 (in the daf-16 (mu86); muIs61 strain) nuclear accumulation and high expression of the SOD-3 ge
3 evealed differences in their cytoplasmic and nuclear accumulation, and data from quantitative PCR ana
5 olyphosphate multikinase (IPMK) and promotes nuclear actin assembly that is required for ATR recruitm
6 ring early Xenopus laevis embryogenesis both nuclear and cell volumes decrease with the nuclear-to-cy
7 es (psaI and csos4A) are encoded by both the nuclear and chromatophore genomes, suggesting that EGT i
8 ions demonstrate that the production of both nuclear and cytoplasmic Esrp1 isoforms through alternati
10 world sand dollar genus Encope, based on one nuclear and four mitochondrial genes, calibrated with fo
12 profiles in previous studies, depending upon nuclear and mtDNA haplotype, the magnitude and direction
15 bly, ARv5es was free from HSP90, exclusively nuclear, and constitutively active similarly as previous
21 karyotic genomes that has essential roles in nuclear architecture, DNA repair and genome stability, a
22 ia is distinct from that in the well-studied nuclear, bacterial, or bacteriophage transcription syste
23 modification state is a major determinant of nuclear blebbing and morphology via its contribution to
26 al axis of human eye lenses with age-related nuclear cataract showed increasing concentration of fluo
28 ctive NCD layers may prolong the lifetime of nuclear cladding and consequently enhance nuclear fuel b
32 signaling pathway that ultimately increases nuclear CREB phosphorylation and, in most cases, express
33 provides critical biophysical insights into nuclear crowding, nucleic acid based pharmaceutical deve
35 al profiling (SHAPE-MaP) to probe PAN in its nuclear, cytoplasmic or viral environments or following
37 inus (AAs 176-192) that contributes to CASZ1 nuclear-cytoplasmic shuttling in a chromosomal maintenan
38 ctive nuclear uptake allows development of a nuclear/cytosolic concentration gradient against a backg
40 essing cells can form an actin cap to resist nuclear deformation in response to physiological mechani
41 ebellar cellular pathology, characterized by nuclear degeneration through nucleophagy-based LaminB1 d
42 pathological feature in most cases of ALS is nuclear depletion and cytoplasmic accumulation of the pr
43 with multiple rounds of DNA replication and nuclear division without cytokinesis, resulting in a mul
44 ell explored in central Europe using ancient nuclear DNA [1, 2], its genetic impact on northern and e
46 e were bred to female MNX mice having FVB/NJ nuclear DNA with either FVB/NJ, C57BL/6J, or BALB/cJ mtD
49 itochondria, TOM and TIM complexes transport nuclear-encoded proteins, whereas the Oxa1 is required f
50 ressed pah1Delta effects on lipid synthesis, nuclear/endoplasmic reticulum membrane morphology, and l
53 al how relaxation of external tethers to the nuclear envelope and internal chromatin-chromatin tether
55 on of the retinoblastoma protein and lamins, nuclear envelope breakdown, and duplication of centrosom
56 ed a heterozygous splice site variant in the nuclear envelope gene SYNE1 in a child with severe dilat
57 oted through chromosome movement mediated by nuclear envelope proteins, microtubules, and dynein.
66 ion and acetylation of FOXO3a results in its nuclear export for degradation and consequent down-regul
72 characterized for its essential role in mRNA nuclear export, cofunctions with Los1 in tRNA nuclear ex
75 utating phosphorylation sites to enhance its nuclear expression induces profound autophagy in culture
77 he basic leucine zipper transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2) plays
80 which was down-regulated in mouse hepatocyte nuclear factor 4A knockout mice; were early-stage tumors
81 nted 29% of all HCCs; expressed a hepatocyte nuclear factor 4A-driven gene network, which was down-re
82 ated with impaired glutathione synthesis and nuclear factor erythroid-derived 2 related factor 2 (NRF
83 d with a decreased GSH/GSSG ratio, augmented nuclear factor erythroid-related factor 2, and increased
84 /Notch-like EGF repeat containing (Dner) and nuclear factor I/A (Nfia), that are each heavily express
85 IkappaBalpha enhances the rate of release of nuclear factor kappa B (NFkappaB) from DNA target sites
86 nate attenuated the HS-induced activation of nuclear factor kappa B and reduced the expression of pro
87 ted T cells to produce receptor activator of nuclear factor kappa-B ligand (RANKL), which, in turn, p
88 atients were less capable in phosphorylating nuclear factor kappa-light-chain-enhancer of activated B
89 of p38 mitogen activated protein kinase and nuclear factor kappa-light-chain-enhancer of activated B
90 aining adapter-inducing IFN-alpha (TRIF) and nuclear factor kappaB (NF-kappaB) causes the apoptosis o
91 ed the pro-inflammatory transcription factor nuclear factor kappaB (NF-kappaB), whereas stable, non-o
92 g to caspase-8-mediated apoptosis as well as nuclear factor kappaB (NF-kappaB)-dependent cell surviva
94 , the repressor of the receptor activator of nuclear factor-kappaB ligand-mediated osteoclastogenesis
95 Mechanistically, Nrp1 deletion activates the nuclear factor-kappaB pathway, which in turn accentuates
97 opathy, characterized by elevated NF-kappaB (nuclear factor-kappaB) activation and TNF (tumor necrosi
98 at infection with HCV leads to activation of nuclear factor-kappaB, resulting in increased expression
101 ice, resulting in quadrupolar satellites for nuclear [Formula: see text] isotopes, whereas NMR of the
102 ines of diverse tissue origin by blockade of nuclear FOXO4 degradation and induction of caspase-depen
103 scale proteomics analysis of cytoplasmic and nuclear fractions from normal versus regenerating mouse
110 chromosome, a finding that helps to resolve nuclear genome organization and indicates monocentric re
111 sconnect, we analyzed 41 mitochondrial and 4 nuclear genomes from passenger pigeons and 2 genomes fro
112 rather than ILS, explains most of the shared nuclear genomic variation between these two species and
114 ropose a model whereby RAPGEF5 activates the nuclear GTPases, Rap1a/b, to facilitate the nuclear tran
116 r prior studies with the bile acid-activated nuclear hormone receptor farnesoid X receptor (FXR) and
118 timicrobial peptide with great potential for nuclear imaging of infectious diseases, as its cationic-
119 ey role in HIV infection by facilitating the nuclear import of the pre-integration complex (PIC) that
121 n infected cells during cytoplasmic transit, nuclear import, and mRNA synthesis.IMPORTANCE The fates
123 L4 biochemical activities by RPS3 along with nuclear interaction during UV and oxidative stress may s
124 Here, I review the evidence of whether mito-nuclear interactions are likely to pose a problem for MR
125 theory, which predicts that deleterious mito-nuclear interactions are unlikely to be much more preval
128 kinase dependent, unforeseen function of the nuclear isoform of the Receptor for Advanced Glycation E
129 upporting the conclusion that RIMA-dependent nuclear IYO accumulation triggers cell differentiation i
130 in Henle's fiber layer (HFL) than the inner nuclear layer (INL) and was highly associated with hyper
131 Microcystoid macular changes in the inner nuclear layer were diagnosed in 52 out of 264 eyes with
135 B pathway and consequently reduces NF-kappaB nuclear localization and downregulates NF-kappaB targets
137 ctional nuclear localization signal and that nuclear localization impairs the ability of ICAP1 to sup
142 tically, we found that DMF treatment reduced nuclear localization of transcriptional coactivator with
143 In particular, ARF knockdown reduced non-nuclear localization of YAP which led to an increase in
145 triphosphate (RanGTP) gradient that imports nuclear localization signal (NLS)-specific cargoes (NLS-
146 ivities of both a peptide-encoded N-terminal nuclear localization signal and C-terminal nuclear expor
147 try to show that ICAP1 contains a functional nuclear localization signal and that nuclear localizatio
148 e these sequences do not correspond to known nuclear localization signal motifs, they represent a new
149 rions parallels effects of the attachment of nuclear localization signal to Sis1, indicating that Cur
160 he exceptionally rich information content of nuclear magnetic resonance (NMR) spectra is routinely us
161 lts of a two-dimensional solid-state (77) Se nuclear magnetic resonance (NMR) spectroscopic study of
162 nolic extract and structurally elucidated by Nuclear Magnetic Resonance (NMR) spectroscopy and mass s
169 ray diffraction, solid fat content by pulsed nuclear magnetic resonance and thermal behaviour by diff
170 Here, using high-accuracy (75)As and (51)V nuclear magnetic resonance measurements, we investigate
171 ur was investigated using time-domain proton nuclear magnetic resonance relaxometry, and related to t
176 metabolic content measured in lymphocytes by nuclear magnetic resonance spectroscopy was altered in s
183 ble-isotope tracer experiments combined with nuclear magnetic resonance-based metabolic analysis demo
185 ial DNA (mtDNA) survey and sequencing of two nuclear markers (AME and RAG-1) from P. theobaldi, from
186 c process in which neutrophils release their nuclear material in the form of neutrophil extracellular
188 ombination, so-called "FLI medium," improves nuclear maturation of oocytes in cumulus-oocyte complexe
189 we review some of the emerging mechanisms of nuclear mechanosensing, which range from changes in prot
191 ics, is among the most promising concepts in nuclear medicine for optimizing and individualizing trea
192 olecular Imaging and the American College of Nuclear Medicine should choose the membership of a radio
193 ges in the separation of the inner and outer nuclear membrane are responsible for the additional fluc
194 Strikingly, we also find that the inner nuclear membrane protein Sun1 antagonizes Sun2 LINC comp
195 ns of RNAs into discrete foci at or near the nuclear membrane triggered by multiple elements; and a n
197 Spartan, the protein encoded by SPRTN, is a nuclear metalloprotease that is involved in the repair o
198 ension, apical constriction and interkinetic nuclear migration, as well as precise molecular control
199 gh-resolution confocal microscopy to analyze nuclear morphology and F-actin rearrangements during the
200 ell measurements of size and cytoplasmic and nuclear morphology in high throughput, but only the fina
201 present a method to detect subtle changes in nuclear morphometrics at single-cell resolution by combi
203 ics and the regulatory mechanisms underlying nuclear movements in root epidermal cells remains limite
204 The 3.3 A structure of a twelve-subunit nuclear Mpp6 exosome bound to RNA shows the central regi
206 ensing applications in diverse ares, such as nuclear nonproliferation, environmental monitoring, geop
207 axiom of choice (ZFC) that there is a simple nuclear nonseparable [Formula: see text]-algebra, which
209 e identify Insensible (Insb), another neural nuclear Notch pathway inhibitor, as a critical direct mi
212 n to the membrane determines the dynamics of nuclear oscillations and, in essence, dynein activity.
213 measure these interactions through both (1)H nuclear Overhauser enhancement (NOE) and paramagnetic re
214 ring is accompanied by relocalization to the nuclear periphery and requires Nup2, suggesting a role f
215 Transport of incoming viral capsids to the nuclear periphery was unaffected by the cholesterol redu
218 eloped to increase the efficiency of dynamic nuclear polarization (DNP) in solid-state NMR studies.
223 to the cytoplasm, docking of the capsid at a nuclear pore, and release of the viral genome into the n
225 vel function for Nesprin-1alpha/Nesprin-1 in nuclear positioning through recruitment of Akap450-media
226 (CsMPs) released from the Fukushima Daiichi Nuclear Power Plant (FDNPP) provide nano-scale chemical
229 changes in the tomato (Solanum lycopersicum) nuclear proteome during infection by the oomycete pathog
232 to function as a physiological ligand for a nuclear receptor and direct environmental sensing as a n
233 irectly facilitates its interaction with the nuclear receptor co-repressor (NCoR1), resulting in repr
234 ting mutation (c.279delG, p.Trp93fs*) of the nuclear receptor interacting protein 1 gene (NRIP1) in a
236 this study, we report overexpression of the nuclear receptor NR4A1 in rhabdomyosarcomas that is suff
237 Accumulation of PIP3 in complex with the nuclear receptor protein, SF1, at damage sites requires
238 e of dietary vitamin A, acts as a ligand for nuclear receptor transcription factors with more than 50
240 We previously showed that Nur77, an orphan nuclear receptor, induces apoptosis by targeting mitocho
241 es suggested that differential expression of nuclear receptors involved in adipogenesis underlie the
242 e effects of SUMOylation on other classes of nuclear receptors, dexamethasone (Dex)-induced trans-rep
243 ption as part of a heterodimer with 14 other nuclear receptors, including the peroxisome proliferator
245 which competitive recruitment of DNA-binding nuclear receptors/transcription factors in trans to hot
247 t the partition of the receptor in different nuclear reservoirs ultimately regulates the concentratio
248 ing the flow of genetic information from the nuclear residence of genes to the disparate, cytoplasmic
250 er successful DNA extraction fragment of the nuclear rhodopsin gene (RH1) and 9 microsatellite region
253 D1 and D2 domains of the large subunit (LSU) nuclear ribosomal RNA (nrRNA) gene and by morphological
255 Differential expression analysis following nuclear RNA-seq of neutrophil active transcriptomes reve
258 Somatic silencing does not require somatic nuclear RNAi but instead requires both maternal germline
259 find that silencing is dependent on germline nuclear RNAi factors and post-transcriptional mechanisms
261 Taken together, our results support a novel nuclear role for SmgGDS in protecting malignant cells fr
262 ogeria syndrome (HGPS), a mutant form of the nuclear scaffold protein lamin A distorts nuclei and seq
265 cortical blebbing is tightly coupled to MRTF nuclear shuttling to promote the SRF transcriptional act
266 2(KI)), which exhibits aberrant beta-catenin nuclear signaling, beta-catenin haploinsufficiency induc
269 cross cells, the fold change in the level of nuclear Smad3 was a more precise outcome of ligand stimu
270 ap resonators, we drive Rabi oscillations on nuclear spins exclusively using electric fields by emplo
271 nanoscale ensembles down to approximately 30 nuclear spins in atomically thin hexagonal boron nitride
273 derstanding of precisely how the position of nuclear spins relative to the electronic spin center aff
277 ional testing (exercise electrocardiography, nuclear stress, or stress echocardiography) or coronary
279 C is considered for applications in advanced nuclear systems, as well as for electronic or spintronic
280 h nuclear and cell volumes decrease with the nuclear-to-cytoplasmic (N/C) volume ratio reaching a max
281 find upregulated extracellular Wg ligand and nuclear trans-synaptic signal transduction, as well as d
283 gulation of biotin utilization and acts as a nuclear transcriptional coregulator of gene expression.
284 rtion mapping, and profiling of the complete nuclear transcriptome, including a ribosomal RNA degrada
285 production and its ability to induce GRalpha nuclear translocation and GRE-dependent GILZ expression.
286 n of glioblastoma stem-like cells drives the nuclear translocation of an intracellular fragment of OD
288 ification in RPE cells, which coincides with nuclear translocation of the lysosomal stress-sensing tr
289 father's lymphocytes showed reduced pSTAT4, nuclear translocation, and impaired IFN-gamma production
293 nuclear GTPases, Rap1a/b, to facilitate the nuclear transport of beta-catenin, defining a parallel n
296 ster) and from specific tRNA loci (e.g., the nuclear tRNA(Gly) and tRNA(Leu), the mitochondrial tRNA(
298 hnetium-99 ((99)Tc) contained in reprocessed nuclear waste and present in contaminated subsurface sys
299 re deuterium and the removal of tritium from nuclear waste are the key challenges in separation of li
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