ライフサイエンスコーパス: nuclear DNA

1 year, an order of magnitude higher than for nuclear DNA.

2 ut shared many haplotypes with the latter at nuclear DNA.

3 polymorphism is linked to differences in the nuclear DNA.

4 ation from organellar DNA in preparations of nuclear DNA.

5 , precluding their use on most alignments of nuclear DNA.

6 3 subunits encoded by both mitochondrial and nuclear DNA.

7 us, whereas APOBEC3A alone efficiently edits nuclear DNA.

8 II trials; however, all of these target only nuclear DNA.

9 ferent subunits encoded by mitochondrial and nuclear DNA.

10 different cells possess variable amounts of nuclear DNA.

11 ove approximately 20 muM, the complex images nuclear DNA.

12 ithful replication of both mitochondrial and nuclear DNA.

13 nstrating the inaccessibility of most of the nuclear DNA.

14 include components that are not specified by nuclear DNA.

15 D4-PLAG1; a fusion between mitochondrial and nuclear DNA.

16 n be caused by mutations in mitochondrial or nuclear DNA.

17 H 3) 2} 1,2-intrastrand d(GpG) cross-link in nuclear DNA.

18 thelia is associated with the degradation of nuclear DNA.

19 reactive oxygen species and fragmentation of nuclear DNA.

20 d Chk1/Chk2 phosphorylation and release from nuclear DNA.

21 mount of the triphosphate form (L-OddCTP) in nuclear DNA.

22 ation, and oligonucleosomal fragmentation of nuclear DNA.

23 roapoptotic protein Bax and fragmentation of nuclear DNA.

24 effects of ferritin iron on the integrity of nuclear DNA.

25 ften enriched in the cytoplasm away from the nuclear DNA.

26 -characterized function is repair of damaged nuclear DNA.

27 r of indels made during replication of yeast nuclear DNA.

28 ell explored in central Europe using ancient nuclear DNA [1, 2], its genetic impact on northern and e

29 was found in 5 cases (mean ratio of mtDNA to nuclear DNA: 239 [95% CI, 217-239] vs 179 [95% CI, 165-1

30 neo; n = 3 individuals) with mtDNA (771 bp), nuclear DNA (3100 bp), and 51 microsatellite loci.

31 Nuclear DNA abnormalities in individual glands were iden

32 and cytochrome c oxidase subunit I (COI)] or nuclear DNA [adenine nucleotide translocator 1 (ANT1) an

33 Finally, enzymatic degradation of nuclear DNA allows us to recover 45% of tight nuclear-bo

34 NA (ALR.mt(NOD)) and the reciprocal with NOD nuclear DNA and ALR mtDNA (NOD.mt(ALR)).

35 ntimicrobial strategy comprising decondensed nuclear DNA and associated histones that are extruded in

36 e range of likely APOBEC3 targets to include nuclear DNA and endogenous retroelements, which have pat

37 iminate invading microorganisms by expelling nuclear DNA and histones to form extracellular web-like

38 damage mitochondrial DNA (mtDNA) as well as nuclear DNA and in turn promote carcinogenesis.

39 essential to prevent uracil accumulation in nuclear DNA and indicate that SHMT1-mediated nuclear de

40 TMZ methylates nuclear DNA and induces cell death; however, the impact

41 Previous studies with protein, nuclear DNA and mitochondrial DNA (mtDNA) markers produc

42 c mouse strains were generated: one with ALR nuclear DNA and NOD mtDNA (ALR.mt(NOD)) and the reciproc

43 ukaryotes (polymerases delta and epsilon for nuclear DNA and polymerase gamma for mitochondrial) are

44 d on the newly synthesized leading strand of nuclear DNA and were present upstream of (G+C)-rich trac

45 Although iPSCs and nt-ESCs shared the same nuclear DNA and yet carried different sources of mitocho

46 liced and unspliced RNA, (b) cytoplasmic and nuclear DNA, and (c) Gag.

47 dependent manner, increased uracil levels in nuclear DNA, and increased genome instability.

48 The amplicon curves for mitochondrial and nuclear DNA, and the correlations among the curves, were

49 FUS is a predominantly nuclear DNA- and RNA-binding protein that is involved in

50 Bax protein expression and fragmentation of nuclear DNA are mediated by NO derived from nNOS.

51 anism by which Ty1 integrase gains access to nuclear DNA as a model for how other retroelements, incl

52 nters the nucleus and reacts with its target nuclear DNA, as determined by platinum atomic absorption

53 t dendritic cells (DCs) can uptake and sense nuclear DNA-associated entities released by dying cells

54 entional SR probes, it can provide images of nuclear DNA at unprecedented resolution.

55 ing phenotypes also in mice with a wild-type nuclear DNA background.

56 t that ribonucleotides are incorporated into nuclear DNA beyond their role in priming Okazaki fragmen

57 The nuclear DNA-binding protein DEK is an autoantigen that h

58 Here we show that HMGB1, a nuclear DNA-binding protein released from necrotic cells

59 otein (HMGB1), originally characterized as a nuclear DNA-binding protein, has also been described to

60 rison of cells with identical oocyte-derived nuclear DNA but different mtDNA shows that either mtDNA

61 tion of the lncRNA RMRP, which is encoded by nuclear DNA but has key functions in mitochondria.

62 Because platelets lack nuclear DNA but retain megakaryocyte-derived mRNAs, the

63 not only are ribonucleotides present in the nuclear DNA, but that they can be incorporated by at lea

64 long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the mechanisms that mediate their trans

65 esults showed that the copy numbers of viral nuclear DNA can vary by as much as 1.8 orders of magnitu

66 en species (ROS) and the decondensing of the nuclear DNA catalyzed by peptidyl arginine deiminase-4.

67 ransferred gene has integrated into sea slug nuclear DNA comes from the finding of a highly diverged

68 l triggering of endocycles results in higher nuclear DNA content (C value) that in some cases has bee

69 The detection of changes in nuclear DNA content by correlating color recovery of H2B

70 use mutants to show that a 16-fold change in nuclear DNA content does not influence the relative size

71 on, as a link in coordinating cell shape and nuclear DNA content in endoreplicated Arabidopsis tricho

72 QF-PCR with flow cytometric determination of nuclear DNA content indicated near perfect agreement bet

73 ype trichomes, which are single cells with a nuclear DNA content of approximately 16C to 32C.

74 n based on both cellular DNA replication and nuclear DNA content.

75 ll size increases are not caused by a higher nuclear DNA content.

76 yed budbreak compared with those with larger nuclear DNA content.

77 t visualization and estimation of changes in nuclear-DNA content in live cells during their developme

78 While the first provides information on nuclear DNA contents across land plants and some algal g

79 Measurement of nuclear DNA contents showed that PL cells were haploid r

80 er reconstructions of chromosome numbers and nuclear DNA contents.

81 s for a 519 bp region of the 18S RNA gene on nuclear DNA correlated appropriately.

82 KGF ameliorated nuclear DNA damage and cytoskeletal rearrangement caused

83 espond to age-related increases in oxidative nuclear DNA damage by forming DNA damage repair foci; ho

84 ased nuclear localization of cDDP, increased nuclear DNA damage by platination, and increased apoptos

85 drial ROS, however, did not cause detectable nuclear DNA damage even when base excision repair was bl

86 Nuclear DNA damage foci were detected in the endothelium

87 in the cell nucleus (K125L), suggesting that nuclear DNA damage is required for toxicity.

88 Nuclear DNA damage occurred later in EAU at day 12.

89 ered as a stereotypic response to unrepaired nuclear DNA damage or to uncapped telomeres.

90 merase in plants and plays a crucial role in nuclear DNA damage repair.

91 ngiectasia mutated (ATM) kinase orchestrates nuclear DNA damage responses but is proposed to be invol

92 Neither mitochondrial nor nuclear DNA damage was detected in the controls.

93 ron's protective effect against H2O2-induced nuclear DNA damage was greater than the cellular antioxi

94 We examined nuclear DNA damage, micronuclei (MN), intracellular ROS

95 PCR-based measurements of mitochondrial and nuclear DNA damage, mtDNA damage was preferentially note

96 We propose that in addition to NO-mediated nuclear DNA damage, the hypoxia-induced increased ratio

97 ial protein oxidation, and mitochondrial and nuclear DNA damage, without interfering with mitochondri

98 Furthermore, PPL2 accumulates at sites of nuclear DNA damage.

99 rf176; EXO5) that functions in the repair of nuclear DNA damage.

100 e insult, such as permeability increases and nuclear DNA damage.

101 n mutation caused elevated mitochondrial and nuclear DNA damage.

102 enerated reactive oxygen species that caused nuclear DNA damage.

103 oint mutation of mitochondrial DNA or with a nuclear DNA defect (44% and 52%, respectively; P<0.001).

104 only independent predictor associated with a nuclear DNA defect (P=0.002; odds ratio 8.43, 95% confid

105 hat it is highly predictive of an underlying nuclear DNA defect.

106 kelihood ratio (5.87) for the diagnosis of a nuclear DNA defect.

107 l feature in mitochondrial disease caused by nuclear DNA defects and single, large-scale mitochondria

108 All eukaryotes have three nuclear DNA-dependent RNA polymerases, namely, Pol I, II

109 to a pattern of isolation by distance, while nuclear DNA did not.

110 In addition to a direct role of nuclear DNA double-strand breaks as inducer of a DNA dam

111 in the Prkdc gene, which encodes a critical nuclear DNA double-stranded break repair protein.

112 for the treatment of mtDNA-driven, and some nuclear DNA-driven, mitochondrial diseases.

113 We show that GSH co-localizes with nuclear DNA during the proliferation of A. thaliana cell

114 BEC3A with a TRIB3 expression vector reduced nuclear DNA editing whereas siRNA knockdown of TRIB3 inc

115 A knockdown of TRIB3 increased the levels of nuclear DNA editing, indicating that TRIB3 functioned as

116 ervation may yield substantial quantities of nuclear DNA, enabling novel applications of ancient DNA

117 -binding factor 1), that associated with the nuclear DNA-encoded lncRNA RMRP and mobilized it to mito

118 n adipocytes similarly induced expression of nuclear DNA-encoded mitochondrial ETC genes, including t

119 tion, the basal expression levels of several nuclear DNA-encoded oxidative damage responsive genes wh

120 ith mutations in the gene NDUFS4, encoding a nuclear DNA-encoded subunit of CI (NADH dehydrogenase ub

121 I) and subcellular organelles (mitochondria, nuclear DNA, etc.) not known to affect either focal adhe

122 However, limited mitochondrial and nuclear DNA evidence conflicts in the timing of PB origi

123 of 2 were investigated and interactions with nuclear DNA explored.

124 sults demonstrated there were alterations in nuclear DNA expression and DNA methylation driven by mtD

125 In situ full-length Rx1 binds nuclear DNA following activation by its cognate pathogen

126 Nuclear DNA fragmentation (ODxmm2) was 147+/-15 in Nx; 7

127 esults suggest that mitochondrial damage and nuclear DNA fragmentation are likely to be critical even

128 Peak nuclear DNA fragmentation in the abnormal LT cohort was

129 O-mediated expression of the Bax protein and nuclear DNA fragmentation in the cerebral cortex of newb

130 al release of apoptosis inducing factor, and nuclear DNA fragmentation resulting in centrilobular nec

131 this leads to mitochondrial dysfunction and nuclear DNA fragmentation, resulting in necrotic cell de

132 ase [GDH] and mitochondrial DNA [mtDNA]) and nuclear DNA fragments were measured in plasma from APAP-

133 nd binds to the Abl interactor 1, SHP-1, and nuclear DNA fragments.

134 To address these issues, we compared nuclear DNA from 32 archaeological maize samples spannin

135 r body transfer: all involve the transfer of nuclear DNA from an egg or zygote containing defective m

136 ave focused on developing methods to recover nuclear DNA from Neanderthal remains.

137 rial Nuclear eXchange mice, that contain the nuclear DNA from one inbred mouse strain, and the mtDNA

138 The movement of nuclear DNA from one vascular plant species to another i

139 d W-linked DNA, but are indistinguishable at nuclear DNA from other common cuckoos.

140 at low levels of genetic capture of maternal nuclear DNA from other species occur within otherwise an

141 Host nuclear DNA further indicated unanticipated gene flow th

142 lude the possibility that some mitochondrial-nuclear DNA fusions observed in cancer occurred years ea

143 chondrial genome encompasses over a thousand nuclear DNA genes plus hundreds to thousands of copies o

144 pecific targeting of the metalloinsertors to nuclear DNA gives rise to their cell-selective cytotoxic

145 Furthermore, interplay between mtDNA and nuclear DNA has been found in cancer cells, necessitatin

146 nor nuclei into recipient oocytes, whose own nuclear DNA has been removed, can result in large number

147 a result of DNA damage, mitochondrial DNA or nuclear DNA has been shown to enter the cytoplasm where

148 nscription and nucleotide excision repair of nuclear DNA, however, whether or not XPD exerts similar

149 at antiviral therapy leads to a reduction in nuclear DNA in a manner consistent with symmetrical dist

150 nd apoptotic cells, but whether C1q binds to nuclear DNA in apoptotic cells remains to be investigate

151 ifetime imaging microscopy (PLIM) probes for nuclear DNA in both live and fixed cells.

152 duck hepatitis B virus (DHBV) cccDNA and HBV nuclear DNA in established cell lines.

153 These properties enable to image nuclear DNA in fixed cells at submicromolar concentratio

154 equency of contact between mitochondrial and nuclear DNA in some somatic cells.

155 Nuclear DNA in the male gamete of sexually reproducing a

156 Genetic analysis confirmed that nuclear DNA in the three infants born so far originated

157 Deletion of DNase1L2 causes retention of nuclear DNA in the tongue epithelium but not in the skin

158 tochondrial myopathies are due to defects in nuclear DNA, including coenzyme Q10 deficiency and mutat

159 tochondrial myopathies are due to defects in nuclear DNA, including coenzyme Q10 deficiency, and muta

160 Nuclear DNA indicated Neanderthals as a sister group of

161 mice exhibited decreased levels of uracil in nuclear DNA, indicating enhanced de novo thymidylate syn

162 Insults to nuclear DNA induce multiple response pathways to mitigat

163 ced enhancement of ROS formation, attenuated nuclear DNA injury, reduced the activation of the nuclea

164 iscordance between mitochondrial (mtDNA) and nuclear DNA introgression detected in North American pop

165 Degradation and modification of nuclear DNA is a central feature of apoptosis, and DNA f

166 hysical studies and a significant portion of nuclear DNA is compacted, a unique effect different from

167 Nuclear DNA is the target responsible for anticancer act

168 Damage to nuclear DNA is thought to be its primary mechanism of ce

169 Nuclear DNA is tightly packaged into chromatin, which pr

170 Chromosomal structure of nuclear DNA is usually maintained by insertion of nucleo

171 Nuclear DNA is wrapped around histones.

172 euchromatin comprises only 25% of the tomato nuclear DNA, it is sufficient to account for approximate

173 acene (DMBA), cisplatin and etoposide induce nuclear DNA leakage into the cytosol that intrinsically

174 Here, we review evidence linking aging to nuclear DNA lesions: DNA damage accumulates with age, an

175 nt correlations were observed between plasma nuclear DNA levels and ex vivo cytokine production.

176 The use of various kinds of nuclear DNA markers is increasing, as are multiple locus

177 Nuclear DNA markers reflect a species tree consistent wi

178 d 467 amplified fragment-length polymorphism nuclear DNA markers, we show that the introduced white s

179 strong genetic differentiation identified by nuclear DNA markers.

180 ed to uncouple the inheritance of mtDNA from nuclear DNA may enable affected women to have a genetica

181 nization of chromatin affects all aspects of nuclear DNA metabolism in eukaryotes.

182 n and can participate in distinct aspects of nuclear DNA metabolism.

183 bred mouse strain to examine the genome-wide nuclear DNA methylation and gene expression patterns of

184 tosis and micronucleus formation, by loss of nuclear DNA methylation, and by an increased fraction of

185 sial; whether DNMT2 functions primarily as a nuclear DNA methyltransferase or as a cytoplasmic tRNA m

186 We found non-coincident clines in mtDNA and nuclear DNA, mirroring directionality of premating isola

187 Hence, the cardiac phenotype of nuclear DNA mitochondrial mutations might be modulated b

188 Cellular processes mediated through nuclear DNA must contend with chromatin.

189 es, despite evidence both compounds increase nuclear DNA mutations and demonstrated B[a]P adduct form

190 luated the minimum prevalence of symptomatic nuclear DNA mutations and symptomatic and asymptomatic m

191 Results suggest that the nuclear DNA mutations that give rise to ADOA in our pati

192 The mitochondria are assembled from both nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) genes.

193 ernally inherited mtDNA, the more than 1,000 nuclear DNA (nDNA) bioenergetic genes, and the epigenomi

194 e action spectra of UVR-induced erythema and nuclear DNA (nDNA) damage.

195 bled from both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) encoded subunits, with complex I enco

196 genase (GDH), mitochondrial DNA (mtDNA), and nuclear DNA (nDNA) fragments can be measured in circulat

197 an evolve different anatomical forms through nuclear DNA (nDNA) mutations permitting exploitation of

198 The adipose tissue mtDNA/nuclear DNA (nDNA) ratio was increased in untreated HIV-

199 In contrast to nuclear DNA (nDNA), mtDNA is more exposed to oxidative d

200 mitochondrial DNA (mtDNA) and the Mendelian nuclear DNA (nDNA).

201 Replication of nuclear DNA occurs in the context of chromatin and is in

202 such as doxorubicin (DXR), intercalate into nuclear DNA of cancer cells, thereby inhibiting their gr

203 an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetop

204 l-hydroxymethyluracil) was discovered in the nuclear DNA of some pathogenic protozoa, such as trypano

205 itively shown to originate from mutations in nuclear DNA or mitochondrial DNA, repair of oxidized, sa

206 Therefore, partial defects in either the nuclear DNA or mtDNA genes or combinations of the two ca

207 sbestos induced a dose-dependent increase in nuclear DNA oxidative damage and MN in SAE cells.

208 without mitosis, resulting in an increase in nuclear DNA ploidy.

209 N or pol nu) is the most recently discovered nuclear DNA polymerase in the human genome.

210 Human DNA polymerase N (PolN) is an A-family nuclear DNA polymerase whose function is unknown.

211 lear antigen (PCNA), the auxiliary factor of nuclear DNA polymerases, plays an important role in regu

212 A nuclear-DNA rate calibration suggests that mohoids diver

213 used whole blood to analyze mitochondrial-to-nuclear DNA ratio (mtDNA/nDNA) using quantitative polyme

214 s, as evidenced by elevated mitochondrial-to-nuclear DNA ratio and increased expression of the mitoch

215 aded intact mtDNA and decreased the mtDNA-to-nuclear DNA ratio.

216 ases in mitochondrial mass, mitochondrial-to-nuclear DNA ratios, and both nuclear and mitochondrial e

217 al effects that it induces did not involve a nuclear DNA related mode of action.

218 lasmic, and how and exactly when it accesses nuclear DNA remains enigmatic.

219 the mechanism by which DLAD gains access to nuclear DNA remains unknown.

220 However, Lig3 inactivation did not result in nuclear DNA repair deficiency, indicating essential DNA

221 , and rLOX-PP localized to radiation-induced nuclear DNA repair foci.

222 These studies implicate the nuclear DNA repair proteins XPB and XPD in a cellular de

223 d in detection of a protein complex with the nuclear DNA repair regulator MRE11 in both cell lines, a

224 These results suggest that, contrary to nuclear DNA repair, mitochondrial DNA repair is not able

225 tial for mtDNA integrity but dispensable for nuclear DNA repair.

226 with HAT1 knock-down display mitosis without nuclear DNA replication and also specific de-repression

227 C6-interacting factors also act in T. brucei nuclear DNA replication and demonstrate that TbORC1/CDC6

228 2) is essential in RNA primer removal during nuclear DNA replication and is important in repairing UV

229 an DNA2, originally identified in yeast as a nuclear DNA replication and repair factor, functions exc

230 Early embryonic development features rapid nuclear DNA replication cycles, but lacks mtDNA replicat

231 n MMR in light of increasing knowledge about nuclear DNA replication enzymology and the rate and spec

232 aintain genome stability, mismatch repair of nuclear DNA replication errors must be directed to the n

233 Perhaps surprisingly, our understanding of nuclear DNA replication in kinetoplastids was limited un

234 study, we show that TbOrc1 is essential for nuclear DNA replication in mammalian-infectious bloodstr

235 Nuclear DNA replication is, arguably, the central cellul

236 liest acting components of the kinetoplastid nuclear DNA replication machinery - the factors that dem

237 cell surface receptor tyrosine kinase to the nuclear DNA replication machinery in cancer cells.

238 In eukaryotic nuclear DNA replication, one strand of DNA is synthesize

239 During nuclear DNA replication, proofreading-deficient DNA poly

240 isiae homologs, Pif1p and Rrm3p, function in nuclear DNA replication, telomere length regulation, and

241 its primase and polymerase activities during nuclear DNA replication.

242 Human UPF1 (hUPF1) is also needed for nuclear DNA replication.

243 anscript levels of mitochondrial DNA but not nuclear DNA respiratory complex subunits, suggesting act

244 Conversely, our nuclear DNA results based on 12 microsatellites detected

245 interferon-inducible protein IFI16 acts as a nuclear DNA sensor following HCMV infection, binding vir

246 reveal that KSHV utilizes the innate immune nuclear DNA sensor IFI16 to maintain its latency and rep

247 also required for stabilization of IFI16, a nuclear DNA sensor.

248 nted the standard barcoding locus (COI) with nuclear DNA sequence data (ITS2) and analyzed congruence

249 al description, as well as mitochondrial and nuclear DNA sequence data, from another molar (Denisova

250 The nuclear DNA sequence diversity among the three Denisovan

251 However, nuclear DNA sequences (n = 77 specimens) revealed extens

252 imescale derived from analyses of multilocus nuclear DNA sequences for Holarctic genera of plethodont

253 amined approximately 32 kilobases of aligned nuclear DNA sequences from 19 independent loci for 169 s

254 Here we present nuclear DNA sequences from Denisova 4 and a morphologica

255 Nuclear DNA sequences from the two molars form a clade w

256 Nuclear DNA staining revealed that ubp3 ubp4 pollen ofte

257 clade "Syngnathiformes" following the latest nuclear DNA studies with some revisions on the included

258 This deletion of pre-existing nuclear DNA suggests that the genetic impact of organell

259 ncient mitochondrial genomes and genome-wide nuclear DNA surveys to reveal that the wisent is the pro

260 Cyclin D1 abundance thus coordinates nuclear DNA synthesis and mitochondrial function.

261 Cyclin D1 thus integrates nuclear DNA synthesis and mitochondrial function.

262 Nuclear DNA synthesis ceased almost immediately followin

263 Cyclin D1 promotes nuclear DNA synthesis through phosphorylation and inacti

264 vision is observed in G2 after completion of nuclear DNA synthesis.

265 lopment, a large proportion of cells undergo nuclear DNA synthesis.

266 ctivates the pRb tumor suppressor to promote nuclear DNA synthesis.

267 hmdC is a constituent of nuclear DNA that is highly abundant in the brain, sugges

268 incorporated in mitochondrial DNA, while in nuclear DNA the ribonucleotide pattern was only altered

269 In nuclear DNA, the levels of 8-oxo-dG in controls and AMD

270 learly distributes genome-wide in vertebrate nuclear DNA, the state of methylation in the vertebrate

271 These drugs bind nuclear DNA to form Pt-DNA cross-links, which arrest key

272 re formed when neutrophils externalize their nuclear DNA together with antimicrobial granule proteins

273 itive role of PARP1 in regulation of various nuclear DNA transactions is well established.

274 e smaller scaffolds (59,630 bp total) of the nuclear DNA unanchored.

275 PPD crystal-stimulated neutrophils and their nuclear DNA undergo morphological changes characteristic

276 Plasma nuclear DNA, used as a marker for general danger-associa

277 nents were derived from ancestry-informative nuclear DNA variants.

278 plains a proportion of the mitochondrial and nuclear DNA variation among moths on different species o

279 the cytokine's activated state) and also to nuclear DNA via its N-terminal CCP module pair (CCP1/2),

280 These results suggest that a nuclear DNA virus can selectively interfere with RNA exp

281 i's sarcoma-associated herpesvirus (KSHV), a nuclear DNA virus, inhibits mRNA export in a transcript-

282 Damage to mitochondrial DNA and nuclear DNA was assessed using a novel long quantitative

283 platin 1,2-intrastrand d(GpG) cross-links on nuclear DNA was confirmed by using a monoclonal antibody

284 in 1,2-intrastrand d(GpG) cross-links on the nuclear DNA was demonstrated by use of a monoclonal anti

285 DNA analysis confirmed that nuclear DNA was identical to donor somatic cells and tha

286 Relative mtDNA copy number as compared with nuclear DNA was measured by quantitative real-time polym

287 platin 1,2-d(GpG) intrastrand cross-links on nuclear DNA was verified.

288 Moreover, mtDNA, not nuclear DNA, was found to have higher levels of backgrou

289 activity of complex II, entirely encoded by nuclear DNA, was not.

290 esions per 10 kb per genome in the mtDNA and nuclear DNA were measured with long-extension polymerase

291 Levels of oxidized mitochondrial and nuclear DNA were not significantly different.

292 0-fold increase in uracil content in hepatic nuclear DNA when fed a folate- and choline-deficient die

293 Bcl-2 protein and increased fragmentation of nuclear DNA, which are prevented by 7-NINA.

294 responsible for the anticancer activity, is nuclear DNA, which is packaged in nucleosomes that compr

295 e mechanism, mitaplatin thereby attacks both nuclear DNA with cisplatin and mitochondria with DCA sel

296 e were bred to female MNX mice having FVB/NJ nuclear DNA with either FVB/NJ, C57BL/6J, or BALB/cJ mtD

297 il extracellular traps (NETs), consisting of nuclear DNA with histones and microbicidal proteins, are

298 n addition, unlike MNase, MPE-Fe(II) cleaves nuclear DNA with little sequence bias.

299 only of the nupt itself but also of flanking nuclear DNA within one generation of transfer.

300 Nuclear DNA wraps around core histones to form nucleosom