ライフサイエンスコーパス: nuclear accumulation

1 se aortic constriction (TAC) because of GRK5 nuclear accumulation.

2 o interact with beta-catenin, inhibiting its nuclear accumulation.

3 SO levels, suggesting potential roles in ASO nuclear accumulation.

4 in fibroblasts, despite its TNFalpha-induced nuclear accumulation.

5 erminal regulatory domain that restricts its nuclear accumulation.

6 xposure, and occurred without significant GR nuclear accumulation.

7 elevated temperatures, and extra-centromeric nuclear accumulation.

8 er store-operated Ca2+ entry (SOCe) and NFAT nuclear accumulation.

9 are required for both nuclear exclusion and nuclear accumulation.

10 r(194) and Pin1 at Ser(16), as well as their nuclear accumulation.

11 ikely in cytosolic foci that regulate PERIOD nuclear accumulation.

12 Cdc24 cellular localization, preventing its nuclear accumulation.

13 me the principal targeting signal conferring nuclear accumulation.

14 m a loss of cytoplasmic HDAC4 as well as its nuclear accumulation.

15 ner, and Hog1 is required for Rtg1/3 complex nuclear accumulation.

16 iable effect on the upper limit of polyamide nuclear accumulation.

17 ocking its virus-induced phosphorylation and nuclear accumulation.

18 osphorylation of S127 residue of YAP and its nuclear accumulation.

19 ts in Elk-1 that determine its stability and nuclear accumulation.

20 ive stretch, suggesting that HDACs block MLP nuclear accumulation.

21 ore, we found that PWR is important for HDA9 nuclear accumulation.

22 stability of the protein and suppressed its nuclear accumulation.

23 cellular G-actin concentration control their nuclear accumulation.

24 with protoporphyrin IX zinc(II) blocked MLP nuclear accumulation.

25 tability in the nucleus, thereby slowing its nuclear accumulation.

26 ncreased the DOX release and facilitated its nuclear accumulation.

27 YC phosphorylation cascade that promoted MYC nuclear accumulation.

28 ntreated patients with AML, leading to eIF4E nuclear accumulation.

29 nteractions through directly regulating YAP1 nuclear accumulation.

30 d by decreased phosphorylation and increased nuclear accumulation.

31 ells, knockdown of E-cad or alpha-cat caused nuclear accumulation and activation of YAP without overt

32 Germline removal increases MML-1 nuclear accumulation and activity.

33 lization that restricts TGFbeta-induced Smad nuclear accumulation and activity.

34 urs at a late post-entry step, with both the nuclear accumulation and chromosomal integration of nasc

35 cells with suppressed PDLIM2 exhibit reduced nuclear accumulation and deneddylation activity of the C

36 Cdc14 activation at anaphase triggers nuclear accumulation and enzymatic activation of Yen1, l

37 Concurrent GAPDH nuclear accumulation and ERK inhibition were required, h

38 ice indicate that deacetylation favors FoxO1 nuclear accumulation and exerts target gene-specific eff

39 thase kinase 3beta inhibition leads to FANCC nuclear accumulation and FA pathway activation, as measu

40 ant mechanism that selectively regulates the nuclear accumulation and function of HIF-1alpha and pote

41 DAF-16 (in the daf-16 (mu86); muIs61 strain) nuclear accumulation and high expression of the SOD-3 ge

42 COP1 in the regulation of UV-B-induced UVR8 nuclear accumulation and in UVR8-mediated UV-B signaling

43 ary cultured neurons, NES mutations increase nuclear accumulation and increase overall aggregation.

44 The latter is triggered by the nuclear accumulation and increased transcriptional activ

45 Additionally, rhubarb inhibited beta-catenin nuclear accumulation and induced its degradation via pro

46 al activity, evidenced by the increased Nrf2 nuclear accumulation and its downstream gene expression.

47 n of TRF2-S rescues kainic acid-induced REST nuclear accumulation and its gene-silencing effects.

48 apid cellular uptake, evident enhancement of nuclear accumulation and less drug efflux in the resista

49 duced alphavbeta3 expression, enhancing Slug nuclear accumulation and MaSC clonogenicity.

50 exon during virus replication, driving hexon nuclear accumulation and particle assembly.

51 gf stimulates beta-catenin stabilization and nuclear accumulation and protects against epithelial cel

52 n importin inhibitor, blocked HE4/importin-4 nuclear accumulation and sensitized HE4-overexpressing o

53 FA also rapidly induced nuclear accumulation and Ser326 phosphorylation of the m

54 ore, the absence of 14-3-3sigma leads to the nuclear accumulation and stabilization of c-Jun, suggest

55 tion of CRABPII at K102 is essential for its nuclear accumulation and subsequent activation of RA sig

56 and proteasomal degradation but promote its nuclear accumulation and subsequent increased transcript

57 TRIM28 stabilizes and promotes the nuclear accumulation and toxicity of both proteins.

58 n of Lats, dephosphorylation of YAP, and YAP nuclear accumulation and transcriptional activation of i

59 Mechanistic investigations revealed that the nuclear accumulation and transcriptional activity of ARv

60 cell cycle reentry, mediated by independent nuclear accumulation and transcriptional activity of fir

61 ytosol and impaired TGF-beta-induced Smad2/3 nuclear accumulation and transcriptional activity.

62 ed AAV capsids, thereby leading to increased nuclear accumulation and transduction.

63 he tyrosine kinase inhibitor BIBF1120, Rad51 nuclear accumulation, and cell cycle arrest at G(2)/M.

64 evealed differences in their cytoplasmic and nuclear accumulation, and data from quantitative PCR ana

65 epeat containing E3 ubiquitin protein ligase nuclear accumulation, and iii) Fyn phosphorylation.

66 nsing of S. aureus RNA, which triggered IRF5 nuclear accumulation, and this could be antagonized by c

67 However, SKN-1 activity and nuclear accumulation are not always correlated, suggesti

68 Sorcin overexpression inhibits ChREBP nuclear accumulation at high glucose and reduced the act

69 Critically, blocking afadin nuclear accumulation attenuated activity-dependent dendr

70 ons leading to rapid Maf1 dephosphorylation, nuclear accumulation, binding to RNA Pol III at Pol III

71 Blocking either HDAC4 activity or its nuclear accumulation blunts these neurodegenerative chan

72 PRMT1 or PRMT4 knockdown did not block Nrf2 nuclear accumulation but inhibited Nrf2 binding to the A

73 ly, their treatments do not facilitate SKN-1 nuclear accumulation, but slightly increased intracellul

74 a HDACs in cardiac muscle, resulting in HDAC nuclear accumulation, but this has not been examined in

75 ors that undergo daily changes in levels and nuclear accumulation by means of complex multisite phosp

76 Dephosphorylation of HDAC5 increases its nuclear accumulation, by accelerating its nuclear import

77 nt rapid nucleocytoplasmic shuttling and its nuclear accumulation depended on SUMO modification at th

78 but bypassing the COP1 requirement for UVR8 nuclear accumulation did not rescue the cop1 mutant UV-B

79 OSM/STAT3 activation promoted SMAD3 nuclear accumulation, DNA binding and induced SMAD3-depe

80 ox dramatically decreases the protein level, nuclear accumulation, DNA binding, and transcriptional a

81 from the androgen receptor by inhibiting its nuclear accumulation downstream of microtubule stabiliza

82 Moreover, Rgf1p nuclear accumulation during replication arrest depends o

83 Nuclear accumulation dynamics were initially rapid, cell

84 morigenicity and, conversely, that promoting nuclear accumulation enhances this, providing the first

85 progression, Ser-33 phosphorylation, and p53 nuclear accumulation from SEPW1 depletion require mitoge

86 serum was identified as a trigger for IRF-5 nuclear accumulation; however, neither IFNalpha nor SLE

87 , beta-catenin Y333 phosphorylation and PKM2 nuclear accumulation in human glioblastoma specimens.

88 oM concentration, concomitant with reduced C nuclear accumulation in infected cells.

89 The reduced nuclear accumulation in IRS1KO was due to protein instab

90 cin-induced FOXO3a Ser-7 phosphorylation and nuclear accumulation in MCF-7 cells.

91 apoptotic/necrotic material triggered IRF-5 nuclear accumulation in monocytes.

92 after PH; however, HDAC5 exhibited transient nuclear accumulation in regenerating liver.

93 e induces the rapid induction of Arc and its nuclear accumulation in striatal neurons.

94 In vivo measurements of phyB nuclear accumulation in the absence of PIF1, -3, -4, and

95 P3 is required for timely NRF2 induction and nuclear accumulation in the estrogen receptor (ER)-posit

96 ants G12S and H50R induce PTEN oxidation and nuclear accumulation in thyroid cancer.

97 phosphorylated at these sites leading to its nuclear accumulation, increased association with pol III

98 We report here that GRK5 nuclear accumulation is dependent on Ca(2+)/calmodulin (

99 or nuclear export sequence demonstrates that nuclear accumulation is required for toxicity in the Dro

100 ever, the mechanism by which CaM facilitates nuclear accumulation is unknown.

101 leus, and certain gene mutations trigger its nuclear accumulation leading to cell transformation and

102 NA and renal expression of Bax, p53, and its nuclear accumulation, mtDNA fragmentation, and a decreas

103 Microscopic evidence of aberrant nuclear accumulation of 5.8S rRNA in La cKO is supported

104 , and HsLap2beta are not sufficient to drive nuclear accumulation of a membrane protein in yeast, but

105 Notably, Ras-induced nuclear accumulation of activated MEK1/2 was reliant on

106 h TGF-beta receptor I (TbetaRI) and inhibits nuclear accumulation of activated Sma- and Mad-related p

107 the cytoplasm and suggest that LSm8 controls nuclear accumulation of all LSm2-7 proteins.

108 ta-cat) and T-cell factor (TCF) and that the nuclear accumulation of alpha-cat depends on beta-cat.

109 Nuclear accumulation of AMPK complexes containing gamma2

110 using specific antisense morpholino promoted nuclear accumulation of beta-catenin and caused ventrali

111 yos, depletion of IQGAP1 reduced Wnt-induced nuclear accumulation of beta-catenin and expression of W

112 further show that Islet1 is required for the nuclear accumulation of beta-catenin and hence for activ

113 In a panel of RCC cell lines, we observed nuclear accumulation of beta-catenin and increased AURKA

114 Nuclear accumulation of beta-catenin and its transcripti

115 1, pGSK3beta, and vimentin along with higher nuclear accumulation of beta-catenin and reduced E-cadhe

116 nt signaling orchestrates a response through nuclear accumulation of beta-catenin in the cell populat

117 Increased nuclear accumulation of beta-catenin, a mediator of cano

118 vation of Smad signaling, leading to reduced nuclear accumulation of beta-catenin, which is crucial f

119 xpression of Wnt target genes, and prevented nuclear accumulation of beta-catenin.

120 tein degradation as well as reduction of the nuclear accumulation of beta-catenin.

121 es partial skipping of the in-frame exon and nuclear accumulation of beta-catenin.

122 t methylation of YAP facilitates Wnt-induced nuclear accumulation of beta-catenin.

123 C-terminal SIMs blocks export and allows the nuclear accumulation of BGLF4.

124 a key role for the TIM NLS in the regulated nuclear accumulation of both proteins.

125 LS) that is required for appropriately timed nuclear accumulation of both TIM and PER.

126 t TIM(DeltaNLS) protein significantly delays nuclear accumulation of both TIM and wild-type PER prote

127 ith c-ABL in the cytoplasm, thereby blocking nuclear accumulation of c-ABL and phosphorylation of p73

128 Peli1 deficiency resulted in the nuclear accumulation of c-Rel, a member of the NF-kappaB

129 3 blocked the iron-induced up-regulation and nuclear accumulation of CCAAT/enhancer-binding protein-d

130 liferation of immune cells, characterized by nuclear accumulation of cell cycle inhibitors, and prese

131 is a ligand for steroidogenic factor 1, and nuclear accumulation of ceramide has been implicated in

132 Nuclear accumulation of Chk1 in CMA-deficient cells comp

133 of intracellular Ca(2+) with ATP caused the nuclear accumulation of ChREBP.

134 onsive element-binding protein) shut-off and nuclear accumulation of class IIa histone deacetylases.

135 IRT1 deficiency induces hyperacetylation and nuclear accumulation of CRABPII, enhancing RA signaling

136 ve night, a brief light pulse induced strong nuclear accumulation of CRTC1 in the SCN.

137 duce the expression of dFmr1 and promote the nuclear accumulation of dFMR1.

138 lexes showed rapid endosomal trafficking and nuclear accumulation of DNA while DOPC-containing formul

139 The nuclear accumulation of DNAS1L3, but not its exit out of

140 8 down-regulated P-gp expression, increasing nuclear accumulation of doxorubicin and cytotoxicity in

141 ore, we demonstrate that IGFBP2 augments the nuclear accumulation of EGFR to potentiate STAT3 transac

142 Nuclear accumulation of eIF4E in patients who have AML i

143 the ETS domain of Elk-1 and demonstrate that nuclear accumulation of Elk-1 involves conformational fl

144 ERK/RSK axis, DR5 upregulation, and elevated nuclear accumulation of Elk1 and CHOP.

145 kinase activity in cells promoted increased nuclear accumulation of Erk3.

146 plexes can interact with PPARalpha to effect nuclear accumulation of FABP and NHR activation.

147 Nuclear accumulation of FABP on drug binding is driven l

148 We further show that nuclear accumulation of FABP1 and FABP2 is dependent on

149 -Aza-2-deoxycytidine (5-azadC) induced rapid nuclear accumulation of FOXO3, ATM-dependent CREB phosph

150 ine/threonine residues and induced prolonged nuclear accumulation of FoxO3a in the cerebral cortex, b

151 Nuclear accumulation of Foxo3a is augmented by a decreas

152 IGF1 and PE both increased nuclear accumulation of GATA4 and phosphorylation at Ser

153 ting that TORC1 activity is required for the nuclear accumulation of Glc7.

154 t that PTH-mediated Sost repression involves nuclear accumulation of HDAC inhibiting the MEF2-depende

155 A similar nuclear accumulation of HDAC4 and HDAC5 was observed in

156 n, HDAC4, HDAC5, and HDAC9, and also induced nuclear accumulation of HDAC4.

157 ity leads to HDAC4 dephosphorylation and the nuclear accumulation of HDAC4.

158 ppression was associated with specific rapid nuclear accumulation of HDAC5 and co-localization with M

159 ol (ISO) or PKA activation results in strong nuclear accumulation of HDAC5 in contrast to nuclear exp

160 sphate (cAMP) signaling induce the transient nuclear accumulation of HDAC5 in rodent striatum.

161 Moreover, nuclear accumulation of HDAC5 under acute ISO/PKA signal

162 P-dependent signaling pathway that regulates nuclear accumulation of HDAC5, suggesting a mechanism to

163 uperoxide scavenging was sufficient to block nuclear accumulation of HIF2alpha in RCC cells.

164 Single-cell analysis revealed that nuclear accumulation of HIF2alpha was inhibited in hCMV-

165 langiectasia mutated (ATM) deficiency causes nuclear accumulation of histone deacetylase 4 (HDAC4) in

166 We previously found that nuclear accumulation of histone deacetylase-4, HDAC4, co

167 Furthermore, preventing the nuclear accumulation of Hog1 had no impact on C. albican

168 e expression, and reveal that stress-induced nuclear accumulation of Hog1 is dispensable for the viru

169 n of any of the conserved residues increases nuclear accumulation of Htt exon 1.

170 In addition, proteasome inhibition induces a nuclear accumulation of IkappaB kinase (IKK)alpha, and i

171 responsible mechanism involves an increased nuclear accumulation of IkappaB kinase beta (IKKbeta) an

172 Mature B cells in the mutant mice displayed nuclear accumulation of inactive IkappaBalpha complexes

173 R3 Tyr-759 phosphorylation and decreased the nuclear accumulation of interferon regulatory factors 3

174 fusion of viral and endosomal membranes, and nuclear accumulation of IRF3 and viral NP occurred concu

175 A-elicited TLR3 Tyr-759 phosphorylation, the nuclear accumulation of IRF3/IRF7, and IFN-beta generati

176 plateauing, and paired tumor biopsies showed nuclear accumulation of key tumor-suppressor proteins, r

177 lated in OA chondrocytes, and that increased nuclear accumulation of lamin A in response to catabolic

178 , Ccl19/Ccr7 signaling reduces the level and nuclear accumulation of maternal beta-catenin and its ax

179 blastomeres of zebrafish blastulae when the nuclear accumulation of maternal beta-catenin marks the

180 Nieuwkoop blastula organizer, marked by the nuclear accumulation of maternal beta-catenin, a transcr

181 cription but inhibited actin polymerization, nuclear accumulation of megakaryoblastic leukemia-1 prot

182 lethality of Tgfb1(-/-) embryos and enhances nuclear accumulation of mothers against decapentaplegic

183 d that finerenone delays aldosterone-induced nuclear accumulation of MR more efficiently than spirono

184 ology, abnormal localization of RanGAP1, and nuclear accumulation of mRNA were found in cortex of Hun

185 F-A and that CCTepsilon is able to alter the nuclear accumulation of MRTF-A after stimulation by seru

186 ormal lung fibroblasts that PGE2 reduced the nuclear accumulation of MRTF-A.SRF complexes and consequ

187 ng and disassembly of cell contacts leads to nuclear accumulation of MRTFs and the activation of the

188 indings provide mechanistic insight into the nuclear accumulation of mutant htt and the selective neu

189 The mechanism underlying this preferential nuclear accumulation of mutant htt in striatal neurons r

190 anoma-associated CDKN2A mutation, leading to nuclear accumulation of mutant p16ink4a.

191 vascular endothelial growth factor A induces nuclear accumulation of myocardin-related transcription

192 Furthermore, nuclear accumulation of myocardin-related transcription

193 the distribution of neuropil aggregates and nuclear accumulation of N-terminal mutant huntingtin in

194 tion upon gemcitabine treatment precedes the nuclear accumulation of NF-kappaB and HIF-1alpha, and su

195 Both Akt and ERK cooperatively promote nuclear accumulation of NF-kappaB by inducing the phosph

196 However, nuclear accumulation of NF-kappaB p65 was not observed i

197 Interestingly, our data demonstrate that nuclear accumulation of NF-kappaB results from phosphory

198 Nuclear accumulation of NFAT was highly dependent on sus

199 Nuclear accumulation of NFAT was severely reduced in ORA

200 somal kinase, pERK1/2, pAKT, pGSK-3beta, and nuclear accumulation of NFAT.

201 ), including p38 MAPKs and ERKs, followed by nuclear accumulation of Nrf2 and downregulation of Keap1

202 Lyn, in mouse hepatoma Hepa-1 cells, led to nuclear accumulation of Nrf2 and up-regulation of Nrf2 d

203 cells with sulforaphane (2.5 mum) increased nuclear accumulation of Nrf2 over 1-4 h.

204 fibroblasts deficient in Src kinases showed nuclear accumulation of Nrf2, induction of Nrf2 and down

205 In turn, PKR stimulates nuclear accumulation of nuclear factor kappaB (NF-kappaB

206 timulated Nrf2-dependent gene expression and nuclear accumulation of nuclear respiratory factor-1, -2

207 ion of STAT3 over AKT1 and ERK1/2 (MAPK3/1), nuclear accumulation of P-Y705-STAT3, STAT3-DNA binding,

208 human colonic carcinoma cells with ST led to nuclear accumulation of p21, resulting in cellular senes

209 ued G(1) arrest, Ser-33 phosphorylation, and nuclear accumulation of p53 induced by SEPW1 depletion,

210 In contrast, nuclear accumulation of p57kip2 resulted in blocked olig

211 utation in human A549 cells showed increased nuclear accumulation of PA and increased viral polymeras

212 of PA-X was also accompanied by accelerated nuclear accumulation of PA protein and reduced suppressi

213 activates its poly(A)RNA binding, leading to nuclear accumulation of PABP1 and poly(A)RNA and thus fa

214 nhibitors FK506 or cyclosporin A resulted in nuclear accumulation of phospho-HDAC1 and was neuroprote

215 Decreased shuttling limits nuclear accumulation of phosphorylated (activated) SRY,

216 Moreover, the nuclear accumulation of phosphorylated IRF-3, which is n

217 c activation of Ras was sufficient to induce nuclear accumulation of phosphorylated MEK1/2 and ERK1/2

218 Nuclear accumulation of phosphorylated Smad1, a primary

219 F-beta in PKD is not clearly understood, but nuclear accumulation of phosphorylated SMAD2/3 in cyst-l

220 on signal was proposed to be involved in the nuclear accumulation of phyB.

221 that tyrosine kinase inhibitors can inhibit nuclear accumulation of PKCdelta.

222 Here, we show that fibroblasts diminish nuclear accumulation of platinum in ovarian cancer cells

223 xposure of human HaCaT keratinocytes induced nuclear accumulation of PRMT1 and PRMT4, histone H4R3 an

224 a rare, accelerated aging disorder caused by nuclear accumulation of progerin, an altered form of the

225 to shrink during metamorphosis, followed by nuclear accumulation of Prospero and cell cycle exit.

226 This work helps explain the nuclear accumulation of PTEN observed in many healthy ti

227 oylation whereas G(i/o) inactivation induces nuclear accumulation of R7BP.

228 Both proteins control the nuclear accumulation of Rgf1p by inhibition of its nucle

229 However, the mechanisms that permit nuclear accumulation of RSK1 remain unknown.

230 her, these findings challenge the dogma that nuclear accumulation of SAPKs is a pre-requisite for SAP

231 We previously observed nuclear accumulation of Ser-552 phosphorylated beta-cate

232 ticulum, less efficient virion secretion and nuclear accumulation of significantly higher amounts of

233 lation of N-terminal S16 in htt promotes the nuclear accumulation of small N-terminal fragments and r

234 ventually leading to the high expression and nuclear accumulation of Snail and beta-catenin, which fa

235 ABA deficiency promoted nuclear accumulation of SNC1, which was essential for it

236 IRS1KOs exhibited low nuclear accumulation of spliced XBP-1 due to its poor st

237 adjacent to a nuclear export signal prevents nuclear accumulation of Stu2 before cells enter mitosis.

238 0007) correlation between IDH1 mutations and nuclear accumulation of TET1, but not with loss of 5hmC.

239 CRCs), and these mutations lead to increased nuclear accumulation of the beta-catenin transcriptional

240 oting cytoplasmic localization, resulting in nuclear accumulation of the clipped protein.

241 ed ERK nuclear target, but it attenuated the nuclear accumulation of the CREB coactivator TORC1 and s

242 However, nuclear accumulation of the DeltaNp63 transcription fact

243 In contrast, SUMOylation was required for nuclear accumulation of the ErbB4 ICD.

244 TORC2 is essential for proper expression and nuclear accumulation of the GFAT1 transcriptional regula

245 Furthermore, RASSF1A reduced nuclear accumulation of the Hippo pathway transcriptiona

246 Most phyA responses require nuclear accumulation of the photoreceptor, but interesti

247 observed overexpression and increased intra-nuclear accumulation of the PRMT5/WDR77 in breast cancer

248 hat decreased p27(kip1) levels and prevented nuclear accumulation of the proapoptotic factor apoptosi

249 Rigid matrix is needed to induce rapid nuclear accumulation of the RARG isoform and for RARG-sp

250 degradation in the cytoplasm, thus reducing nuclear accumulation of the transcription factor in the

251 hway restricts cellular growth by preventing nuclear accumulation of the Yes-associated protein (YAP)

252 n fused to green fluorescent protein, led to nuclear accumulation of this chimeric protein, indicatin

253 In addition, loss of telethonin mRNA and nuclear accumulation of this protein is associated with

254 ls expressing the mutant Ku are deficient in nuclear accumulation of TLC1, as expected from the RNA-b

255 d to form proper nuclear pores, leading to a nuclear accumulation of total mRNA and abnormal activati

256 CD4 T cell targets, we visualized changes in nuclear accumulation of transcription factors at time po

257 F6 and c-SRC into lipid rafts and preventing nuclear accumulation of transcriptional activator NFATc1

258 interaction and enhanced ATF6 processing and nuclear accumulation of transcriptionally active ATF6, i

259 charide-(LPS)-cell stimulation, which causes nuclear accumulation of TRX-1 and enhanced transcription

260 In fact, TrxR-1 inhibition prevents nuclear accumulation of TRX-1 and LPS-stimulated hyperpr

261 blocks exportin 1 (XPO1) function, leads to nuclear accumulation of tumor suppressor proteins, and i

262 of paired tumor biopsies revealed increased nuclear accumulation of tumor suppressor proteins, decre

263 ntified SINEs that inhibit CRM-1 and promote nuclear accumulation of tumor-suppressor proteins in pan

264 UV-B photoreception stimulates nuclear accumulation of UVR8 in a presently unknown mann

265 OGENIC 1 (COP1) is required for UV-B-induced nuclear accumulation of UVR8, but bypassing the COP1 req

266 nvironment by inducing hypoxia increases the nuclear accumulation of villin.

267 e postentry step of infection to prevent the nuclear accumulation of viral cDNA.

268 rus type 1 (HIV-1) infection, inhibiting the nuclear accumulation of viral cDNAs.

269 hat antibodies to hsc70 significantly reduce nuclear accumulation of wild type SRY and mutant derivat

270 Nuclear accumulation of WWOX is regulated by its K63-lin

271 aluronan caused nuclear depletion of FRMD4A, nuclear accumulation of YAP and reduced SCC growth and m

272 c-like stemness of PGCCs was associated with nuclear accumulation of YAP, a key mediator of the Hippo

273 Notably, FRMD4A attenuation caused nuclear accumulation of YAP, suggesting a potential role

274 n cancers strongly correlated with increased nuclear accumulation of Yap1, indicating that the effect

275 nhibits Hippo signaling, leading to enhanced nuclear accumulation of YAP1, which interacted with and

276 h uncoupled Mst1/2 from Lats1/2 and promoted nuclear accumulation of Yap1.

277 and p38 MAPK-dependent cascade that leads to nuclear accumulation of Yes-associated protein (YAP) and

278 tment of RCC cells did not impair HIF-1alpha nuclear accumulation or transcriptional activity, and ha

279 her lack of protein phosphorylation, lack of nuclear accumulation, or transcriptional and/or translat

280 n C-terminal module and PIF3, abrogates PHYB nuclear accumulation, photobody biogenesis, and PIF3 deg

281 1 transcriptional activation showed that the nuclear accumulation rate of change of the signaling fac

282 v-Src, and Src kinase induction of Trop2 ICD nuclear accumulation required cyclin D1.

283 FAK, Src, PI3K, or PDK1 activity blocked YAP nuclear accumulation stimulated by adhesion to fibronect

284 TGF-beta induced Olfm2 nuclear accumulation, suggesting that Olfm2 may be invol

285 ylation activates the SAPK, and promotes its nuclear accumulation that is necessary for the expressio

286 Moreover, DeltaNp63alpha promotes YB-1 nuclear accumulation thereby reducing the amount of YB-1

287 hibits LPS-induced STAT5 phosphorylation and nuclear accumulation, thereby attenuating its transcript

288 Fbx4 results in cyclin D1 stabilization and nuclear accumulation throughout cell division.

289 We isolated acinar cells and measured NFAT nuclear accumulation, trypsin activity, and expression o

290 nt nuclear import, with an increased rate of nuclear accumulation upon addition of both CaM and hsc70

291 ut not poly-d-lysine or laminin, induced YAP nuclear accumulation via the FAK-Src-phosphatidylinosito

292 al mutations in SRY that specifically impair nuclear accumulation via this pathway resulting in XY se

293 d nuclear factor of activated T cells (NFAT) nuclear accumulation was abrogated by either antioxidant

294 aemia, increased beta-catenin signalling and nuclear accumulation was identified in osteoblasts and t

295 ever, the genetic mechanisms controlling IYO nuclear accumulation were unknown, and the evidence that

296 AKT inhibition alone maximally induced GAPDH nuclear accumulation, whereas MEK/ERK inhibition alone h

297 up-regulated class I and II HDACs and their nuclear accumulation, whereas PSS (12 +/- 4 dynes/cm(2))

298 Mechanistically, SIH did not lead to GRK5 nuclear accumulation, which was confirmed in vitro as in

299 ly increased JunB reporter activity and JunB nuclear accumulation, which were inhibited by the A2B re

300 binding protein calmodulin (CaM) for optimal nuclear accumulation, with clinical mutations in SRY tha