ライフサイエンスコーパス: nuclear condensation

1 motes efficient erythroblast enucleation and nuclear condensation.

2 These cells appeared to be undergoing nuclear condensation.

3 GE2- and cAMP-mediated DNA fragmentation and nuclear condensation.

4 loss of membrane phospholipid asymmetry, and nuclear condensation.

5 u at 24 h, when 20% of infected cells showed nuclear condensation.

6 mbrane leakage preceded the manifestation of nuclear condensation.

7 glycophorin A expression, and chromatin and nuclear condensation.

8 swellings, somal chromatolytic changes, and nuclear condensation.

9 -3 and PARP cleavage, DNA fragmentation, and nuclear condensation.

10 and caused mitochondrial depolarization and nuclear condensation.

11 substrate, poly(ADP-ribose) polymerase, and nuclear condensation.

12 of mitochondrial membrane potential, before nuclear condensation.

13 procaspase-7 activation, PARP cleavage, and nuclear condensation.

14 h-affinity binding to DNA and very efficient nuclear condensation.

15 -like activity, Annexin V incorporation, and nuclear condensation.

16 a reduction in cell size and an increase in nuclear condensation.

17 n phosphorylation, caspase-3 activation, and nuclear condensation.

18 terized by internucleosomal DNA cleavage and nuclear condensation.

19 within 30 min, before cellular shrinkage or nuclear condensation.

20 calculated as the fraction of cells showing nuclear condensation.

21 tive features such as cellular shrinkage and nuclear condensation.

22 11.8 +/- 0.50 vs. 3.3 +/- 0.26; p < 0.0001), nuclear condensation (10.9 +/- 0.58 vs. 3.4 +/- 0.20; p

23 In particular, E2F-2 deletion impairs nuclear condensation, a morphological feature of maturin

24 al progenitors and other cell types leads to nuclear condensation accompanied by large-scale changes

25 Nuclear condensation accompanied ejection while the loss

26 sequence: formation of cytoplasmic blebs and nuclear condensation after 3 hours; nuclear fragmentatio

27 The extent of nuclear condensation and caspase activation was also les

28 Nuclear condensation and cleaved caspase-3 were detected

29 rapid externalization of phosphatidylserine, nuclear condensation and collapse, and single-stranded D

30 morphologic changes, histologic evidence of nuclear condensation and degeneration, and flow-cytometr

31 ures like cell shrinkage, membrane blebbing, nuclear condensation and DNA fragmentation.

32 aspase-1-mediated cell death did not exhibit nuclear condensation and DNA fragmentation.

33 rous erythroid genes and is characterized by nuclear condensation and extrusion during terminal devel

34 These findings imply that nuclear condensation and extrusion during terminal eryth

35 Ultrastructural analysis confirmed nuclear condensation and formation of apoptotic-like bod

36 both cell types, which was characterized by nuclear condensation and fragmentation and activation of

37 This cell death was found to involve nuclear condensation and fragmentation and DNA cleavage,

38 e potential (DeltaPsi), DNA degradation, and nuclear condensation and fragmentation characteristic of

39 To detect apoptotic cells, we used nuclear condensation and fragmentation or terminal dUTP

40 Cells with nuclear condensation and fragmentation were scored as ap

41 ced by poly(ADP-ribose) polymerase cleavage, nuclear condensation and fragmentation, and hypodiploid

42 ormation of apoptotic bodies, detachment and nuclear condensation and fragmentation, in cells transfe

43 uced typical features of apoptosis including nuclear condensation and fragmentation, oligonucleosomal

44 SF-21 cell line induced apoptosis displaying nuclear condensation and fragmentation, oligonucleosomal

45 lytic vacuole shrinkage and degradation, and nuclear condensation and fragmentation.

46 ation, and caspase activation and results in nuclear condensation and fragmentation.

47 1 and caffeine, induced mitosis and abnormal nuclear condensation and increased the protein kinase ac

48 eath induced via CD95 (Fas), as evidenced by nuclear condensation and membrane blebbing, but did not

49 sequently undergo apoptosis, as indicated by nuclear condensation and poly(ADP-ribose) polymerase cle

50 ntiation associated with the onset of global nuclear condensation and reduced cell proliferation.

51 anslation of protamine 1 leads to precocious nuclear condensation and sterility.

52 The percentage of cells exhibiting nuclear condensation and/or fragmentation as well as hig

53 from the mitochondria, caspase-3 activation, nuclear condensation, and an orderly progression of hair

54 f apoptosis: cell shrinkage, cytoplasmic and nuclear condensation, and cell blebbing.

55 volume changes, intracellular acidification, nuclear condensation, and chromosomal digestion ("ladder

56 GrnA-induced membrane perturbation, nuclear condensation, and DNA damage are unimpaired by c

57 cell death involving cytoplasmic shrinkage, nuclear condensation, and DNA fragmentation characterist

58 inhibition reversed BSIA membrane blebbing, nuclear condensation, and DNA fragmentation.

59 of apoptotic cells including cell shrinkage, nuclear condensation, and DNA fragmentation.

60 hropoiesis include global gene inactivation, nuclear condensation, and enucleation to yield circulati

61 , with reduction in cell size, chromatin and nuclear condensation, and enucleation.

62 area, persistent ckit expression, incomplete nuclear condensation, and lower rates of enucleation.

63 apoptotic signs including membrane blebbing, nuclear condensation, and reduction of mitochondrial mem

64 th vacuolization and mitochondrial swelling, nuclear condensation, and sustained plasma membrane.

65 aining showed DNA fragmentation and profound nuclear condensation around the injection site.

66 ructs were tested on cell toxicity using our nuclear condensation assay and on mitochondrial viabilit

67 DNA damage appears to precede nuclear condensation at E7.5, suggesting a defect in DNA

68 de, we observed laddering of genomic DNA and nuclear condensation, both hallmarks of apoptotic cells.

69 antly protect from cell death as measured by nuclear condensation, caspase activation, PARP degradati

70 eath by apoptosis was confirmed by increased nuclear condensation, changes in membrane morphology, an

71 pressed exhibit caspase 3 activation and the nuclear condensation characteristic of apoptosis.

72 cell shrinkage, plasma membrane blebbing and nuclear condensation--characteristic of apoptosis.

73 s demonstrated changes resembling apoptosis: nuclear condensation, chromatin fragmentation, and forma

74 plicing factors Sm and SC35 persisted during nuclear condensation, consistent with effective transcri

75 Global nuclear condensation, culminating in enucleation during

76 Lastly, nuclear condensation did not occur as part of the toxici

77 acrophages, which contrasted with the marked nuclear condensation displayed by control cells undergoi

78 through inducing cell apoptosis confirmed by nuclear condensation, DNA cleavage, and accumulation of

79 n was followed by apoptosis as determined by nuclear condensation, DNA fragmentation, and annexin V b

80 metry analyses were used to detect apoptotic nuclear condensation, DNA fragmentation, and changes in

81 Nuclear condensation during spermiogenesis is accomplish

82 ncer cell selective nuclear internalization, nuclear condensation, fragmentation, and eventually anti

83 , SNCEE did not induce caspase activation or nuclear condensation/fragmentation suggesting that PS ex

84 ptosis, characterized by caspase activation, nuclear condensation/fragmentation, and membrane blebbin

85 ells, including marked caspase-3 activation, nuclear condensation/fragmentation, but with swollen cyt

86 rial membrane potential, cell shrinkage, and nuclear condensation in a caspase-dependent fashion.

87 Staining with propidium iodide showed no nuclear condensation in cells.

88 Morphological examination revealed nuclear condensation in dying wt or E7 cells but nuclear

89 (1) peak in the attached cell population and nuclear condensation in the floating cell population.

90 nd propidium iodide staining showed profound nuclear condensation in the NMDA or QA-treated striatum.

91 creased intracellular ATP levels and induced nuclear condensation in these cells.

92 is followed by caspase activation, apoptotic nuclear condensation, loss of membrane potential, and, f

93 jury in glutathione-depleted preOLs included nuclear condensation, margination of chromatin, and mito

94 classical hallmarks of apoptosis, including nuclear condensation, membrane blebbing, caspase activat

95 Nuclear condensation, membrane permeability, and interle

96 n (DCD) that is expressed as cytoplasmic and nuclear condensation, neuron shrinkage, and failure of p

97 licate CaMKIV in chromatin remodeling during nuclear condensation of spermatids.

98 Furthermore, the C127/508 cells did not show nuclear condensation or DNA fragmentation detected by in

99 or 2d induced cytosolic vacuolation, but not nuclear condensation or DNA fragmentation.

100 t 72 hours post-ARDS criteria as measured by nuclear condensation (P < 0.001).

101 such apoptotic markers as DNA fragmentation, nuclear condensation, poly(ADP-ribose) polymerase cleava

102 In apoptotic cells, DNA fragmentation and nuclear condensation result from caspase-3-mediated prot

103 sensory cells were dependent on the stage of nuclear condensation, suggesting a specific role for MMP

104 d caspase activation and activity along with nuclear condensation that occurs independent of actin cy

105 histones, HILS1 may participate in spermatid nuclear condensation through a mechanism distinct from t

106 eprivation; LY 294002-induced death included nuclear condensation, was blocked by cycloheximide, and

107 ntation and TUNEL-positive nuclei as well as nuclear condensation were abolished by the NMDA receptor

108 cells displayed irreversible cytoplasmic and nuclear condensation while maintaining intact membranes.