ライフサイエンスコーパス: nuclear export

1 uclear export, cofunctions with Los1 in tRNA nuclear export.

2 is critical for pre-mRNA processing and mRNA nuclear export.

3 cer of p53 sumoylation by enhancement of its nuclear export.

4 es in structural remodelling checkpoints and nuclear export.

5 SIRT6-mediated deacetylation results in PKM2 nuclear export.

6 cell lung cancer cells to receptor-dependent nuclear export.

7 protein O1 (FOXO1) phosphorylation and FOXO1 nuclear export.

8 4 as the specific transporter mediating PKM2 nuclear export.

9 serve overlapping but distinct roles in tRNA nuclear export.

10 and mRNA nuclear export machineries in tRNA nuclear export.

11 ex, known to function in mRNA biogenesis and nuclear export.

12 the recognition of CTE-RNA and promotes its nuclear export.

13 unspliced tRNA, a hallmark of defective tRNA nuclear export.

14 osis is driven by its apoptotic cell-induced nuclear export.

15 and requires an adaptor for CRM1 binding for nuclear export.

16 h was associated with HDAC5 and mediated its nuclear export.

17 with BCL-XL and XIAP mRNAs to promote their nuclear export.

18 ctin, which binds to MRTF-A and promotes its nuclear export.

19 r accumulation of Rgf1p by inhibition of its nuclear export.

20 uitin and its complex formation with ATM for nuclear export.

21 Our study provides a novel insight into MLV nuclear export.

22 asculature via regulation of CRM-1-dependent nuclear export.

23 f the importin-beta family, function in tRNA nuclear export.

24 rizes on viral transcripts and directs their nuclear export.

25 transcripts were also defective in terms of nuclear export.

26 t function as a docking site for mRNP during nuclear export.

27 SGK1 is required for viral ribonucleoprotein nuclear export.

28 mal region maintenance 1 (CRM1) mediates p53 nuclear export.

29 es crucial for 14-3-3 binding and subsequent nuclear export.

30 ed RNP complex that links transcription with nuclear export.

31 mpaction of mature transcripts to facilitate nuclear export.

32 to identify candidates that function in tRNA nuclear export.

33 e that the proteome can be regulated by tRNA nuclear export.

34 RNAs are fully processed and appropriate for nuclear export?

35 The nuclear export activity of HDAg-L is important for HDV p

36 nd human Lsg1, which promotes release of the nuclear export adapter from the large ribosomal subunit.

37 Here, we show that depletion of the nuclear export adaptor SRSF1 prevents neurodegeneration

38 D to the nucleus is limited by CRM1-mediated nuclear export and by an uncharacterized mechanism of cy

39 gical functions such as pre-mRNA processing, nuclear export and cap-dependent protein synthesis.

40 In addition, nuclear export and cytoplasmic retention cooperate to ex

41 rome critical region gene 8 and promotes its nuclear export and degradation by calpain.

42 -induced CDK-interacting protein 1 (p21Cip1) nuclear export and degradation in facilitating human aor

43 ssed arginine-methylation of FOXO3 promoting nuclear export and degradation of the JNK phosphorylated

44 ifferences between Crm1 orthologs that alter nuclear export and determine cellular tropism for viral

45 n uncovered putative novel pathways for tRNA nuclear export and extensive links between tRNA biology

46 tor (GPCR) agonist, thrombin-induced p21Cip1 nuclear export and its degradation in promoting HASMC pr

47 proteins involved in RNA splicing, editing, nuclear export and nucleolar function.

48 cubated with leptomycin b and MG132 to block nuclear export and proteasome activity, respectively.

49 ve for only GPCR but not RTK agonist-induced nuclear export and proteolytic degradation of p21Cip1 in

50 nting that Los1 participates in both primary nuclear export and re-export of tRNAs to the cytoplasm.

51 at steady state by phosphorylation-dependent nuclear export and subsequent proteolysis in the cytopla

52 uitin E3 ligase for PSD-95, which results in nuclear export and synaptic accumulation of Mdm2 as well

53 eIF4E drives nuclear export and translation of BCL6, MYC, and BCL2 mR

54 and SRSF7, regulators of pre-mRNA splicing, nuclear export and translation-interact with RNA in diff

55 tifs and involved in splicing, messenger RNA nuclear export and/or translation were significantly enr

56 for LTD as inhibition of STAT3-DNA binding, nuclear export, and gene transcription all prevented LTD

57 his process involves CP and RP dissociation, nuclear export, and independent vacuolar targeting of CP

58 th on Rev subcellular trafficking, viral RNA nuclear export, and infectious virion production.

59 processing to remove the leader and trailer, nuclear export, and splicing if applicable, while multip

60 The factors that mediate splicing, nuclear export, and translation initiation are recruited

61 h proteins play important roles in splicing, nuclear export, and translation.

62 sing, including transcription, splicing, and nuclear export are disrupted in clbn, either through int

63 the elements and signals involved in MRTF-A nuclear export are largely unexplored.

64 tivation; thus, both viral RNA synthesis and nuclear export are required for IFN induction by influen

65 ture cells show that viral RNA synthesis and nuclear export are required to activate this response.

66 , and EAR-like domain, which participates in nuclear export, are necessary to maintain higher nuclear

67 se that phosphorylates Snail1 precluding its nuclear export but not its polyubiquitination.

68 tubules, various stages of capsid formation, nuclear export by budding into the perinuclear space, te

69 ng of expanded C9orf72 pre-messenger RNA for nuclear export by inappropriate association with messeng

70 pression of importin-alpha and inhibition of nuclear export by leptomycin B resulted in predominant n

71 s are selectively sensitive to inhibition of nuclear export by Leptomycin B.

72 The nuclear export carrier protein CRM1 recognizes this NES-

73 characterized for its essential role in mRNA nuclear export, cofunctions with Los1 in tRNA nuclear ex

74 propose a new model for the assembly of the nuclear export complex of Influenza A vRNPs.

75 vide the first view of an assembled HIV-host nuclear export complex using single-particle electron mi

76 rferes with the stability of the vRNP-M1-NEP nuclear export complex, probably mediated by its highly

77 xor is the first oral selective inhibitor of nuclear export compound tested for cancer treatment.

78 of selinexor, an oral selective inhibitor of nuclear export compound, in patients with advanced soft

79 ovel, first-in-class, selective inhibitor of nuclear export compound, which blocks exportin 1 (XPO1)

80 Surprisingly, SUMO-mediated p53 nuclear export depends on the SUMO-interacting motif (SI

81 ith a second, RNA-bound precomplex after its nuclear export dimerizes the motor and activates process

82 nuclear accumulation of HDAC5 in contrast to nuclear export driven by Ca(2+)-calmodulin protein kinas

83 Striking behaviors include "burst" RNA nuclear export dynamics regulated by HIV-1's Rev respons

84 expand on mechanisms known to be mediated by nuclear export factor 1 (NXF1) by describing SR proteins

85 Nuclear export factor 1 (NXF1) exports mRNA to the cytop

86 enome-wide shRNA-based screen, we identified nuclear export factor 3 (NXF3) as a transporter that alt

87 ITA, impair its ability to interact with the nuclear export factor CRM1, and enhance CIITA-induced ge

88 ation by increasing the interaction with the nuclear export factor CRM1.

89 he Mex67:Mtr2 complex is the principal yeast nuclear export factor for bulk mRNA and also contributes

90 at the Ran-binding protein RanBP3L acts as a nuclear export factor for Smad1/5/8.

91 d by a GTPase that blocks recruitment of the nuclear export factor Nmd3 until remodeling of the pre-r

92 ulted in cytoplasmic accumulation of the 60S nuclear export factor PA2G4, aberrant ribosome profiles,

93 ex (also known as TAP:p15) is a general mRNA nuclear export factor that is conserved from yeast to hu

94 The splicing and nuclear export factor U2AF65 has the opposite effect, de

95 However, depletion of the nuclear export factors XPO1 or MEX67 recapitulates the e

96 ta show that Mex67-Mtr2 functions in primary nuclear export for a subset of yeast tRNAs.

97 ion and acetylation of FOXO3a results in its nuclear export for degradation and consequent down-regul

98 te increase of cardiac preload induced HDAC4 nuclear export, H3K9 demethylation, HP1 dissociation fro

99 Genome-wide analysis revealed that Hsf1 nuclear export immediately decreased basal transcription

100 to the viral polymerase, its function during nuclear export implicates interaction with viral ribonuc

101 ar nuclear export machinery to promote their nuclear export.IMPORTANCE Influenza A virus is a major p

102 yelocytic leukaemia (PML) is mediated by its nuclear export in a chromosomal maintenance 1 (CRM1)-dep

103 ephosphorylated Smad1/5/8 and mediates their nuclear export in a Ran-dependent manner.

104 K signaling had virtually no effect on FoxO1 nuclear export in controls, in contrast to attenuated ex

105 n-containing mRNAs are subject to restricted nuclear export in higher eukaryotes.

106 To evaluate the role of nuclear export in maintaining localization, we inhibited

107 us mRNAs required individual SR proteins for nuclear export in vivo.

108 proposed, including mRNA stabilization, mRNA nuclear export, increased polyadenylation, and transcrip

109 tion of ATM, and IKKgamma/NEMO-dependent ATM nuclear export, indicating activation of the DNA damage

110 Nuclear export inhibition by ORF10 requires an interacti

111 Cell treatment with the nuclear export inhibitor leptomycin B did not prevent AM

112 ocalized to the nucleus in the presence of a nuclear export inhibitor.

113 Nuclear export is a key, irreversible step in pre-riboso

114 sis reveals a subset of cellular mRNAs whose nuclear export is blocked by ORF10 with the 3' UTRs of O

115 nd association analyses show that PGC-1alpha nuclear export is CRM-1 dependent.

116 As tRNA nuclear export is essential, we previously interrogated

117 tRNA nuclear export is of particular interest because it is e

118 HDAC5 nuclear export is required for axon regeneration, as exp

119 ive GANP-dependent transcripts showed faster nuclear export kinetics than representative transcripts

120 ata implicate roles for the protein and mRNA nuclear export machineries in tRNA nuclear export.

121 king viral RNAs to the cellular CRM1/Ran-GTP nuclear export machinery through the activity of Rev's p

122 adaptor between viral mRNAs and the cellular nuclear export machinery to promote their nuclear export

123 laceholder site linked to recruitment of the nuclear export machinery.

124 etween the viral mRNAs and the cellular mRNA nuclear export machinery.

125 y for nascent chain-60S complexes depends on nuclear export mediator factor (NEMF).

126 NA degradation is cytoplasmic such that mRNA nuclear export must represent an important level of regu

127 After nuclear export, myosin-bound She3p joins the ASH1 mRNP t

128 pathway, while ERK phosphorylation and FoxO1 nuclear export occur independently of insulin signaling.

129 r damage, class IIa HDAC phosphorylation and nuclear export occurred, paralleled by dystrophin and ne

130 X-2) mRNA export complex, promotes selective nuclear export of a specific subset of mRNAs whose trans

131 the cellular factor NXF1 is involved in the nuclear export of both spliced and unspliced viral RNAs,

132 2:Nup1 interaction facilitates the efficient nuclear export of bulk mRNA together with the re-positio

133 tration of SRSF1 triggers the NXF1-dependent nuclear export of C9ORF72 transcripts retaining expanded

134 gent that induces oxidative stress, promoted nuclear export of ectopically expressed Nurr1 in HEK293T

135 genes is further enhanced by inhibiting the nuclear export of endogenous CIITA.

136 uggests that MBNL1 and U2AF65 play a role in nuclear export of expHTT RNA.

137 the nuclear export receptor NXF1/TAP in the nuclear export of gammaretroviral RNA transcripts.

138 response element (RRE), which regulates the nuclear export of gRNAs and other intron-retaining viral

139 s identify nuclear calcium as a regulator of nuclear export of HDAC4 and HDAC5.

140 diated down-regulation of TAP or Aly reduced nuclear export of HDAg-L and assembly of HDV virions.

141 However, the mechanisms of HDAg-L-mediated nuclear export of HDV ribonucleoprotein are not clear.

142 Calcium-dependent nuclear export of histone deacetylase 1 (HDAC1) was show

143 t protein kinase II activation and prevented nuclear export of histone deacetylase 4 after adrenergic

144 )/calmodulin-dependent protein kinase II and nuclear export of histone deacetylases.

145 Here we show that engineered nuclear export of Hsf1 results in cytotoxicity associate

146 ion of Maintenance 1 (CRM1) protein mediates nuclear export of hundreds of proteins through recogniti

147 binds to the HIV-1 Rev protein and mediates nuclear export of incompletely spliced viral RNAs.

148 1 (CRM1), the HIV-1 Rev protein mediates the nuclear export of incompletely spliced viral transcripts

149 Nuclear export of influenza virus ribonucleoprotein (vRN

150 he essential viral Rev protein that mediates nuclear export of intron-bearing late-stage viral mRNAs.

151 dentified ALYREF-binding motifs that promote nuclear export of intronless mRNAs.

152 t of p120ctn in complex with MUC1-CT and the nuclear export of kaiso in complex with p120ctn.

153 he possibility that a phenotypically similar nuclear export of large RNAs is cargo driven.

154 Exportin-1 (XPO1) is the key mediator of nuclear export of many tumor suppressor proteins and is

155 Gastrin-induced nuclear export of menin via cholecystokinin B receptor (

156 ed that CRM1 inhibitors in neurons prevented nuclear export of molecules associated with axonal damag

157 atory mechanism involving the NMD3-dependent nuclear export of mRNA cargos, suggesting a shared platf

158 re where it carries out an essential role in nuclear export of mRNA.

159 he coordination of synthesis, processing and nuclear export of mRNAs.

160 The TREX complex (TREX) plays key roles in nuclear export of mRNAs.

161 has been the only exporter known to execute nuclear export of newly transcribed intron-containing pr

162 ls, and these TGF-beta-induced responses and nuclear export of NR4A1 are blocked by NR4A1 antagonists

163 Thus, TGF-beta-induced nuclear export of NR4A1 in TNBC cells plays an essential

164 ed migration of MDA-MB-231 cells by blocking nuclear export of NR4A1, which is an essential step in T

165 increased nuclear localization of Bach-1 and nuclear export of Nrf2, which are important negative and

166 Nuclear export of p57kip2 was correlated with promoted m

167 Nuclear export of partially spliced or unspliced HIV-1 R

168 eraction with NXF1 specifically inhibits the nuclear export of pathological C9ORF72 transcripts, the

169 te RNA polymerase III transcription with the nuclear export of pre-tRNA.

170 ecessity of a GEF to promote GTP-binding and nuclear export of Ran, the nuclear localization of Ran w

171 ev protein to the RRE in vivo and influenced nuclear export of RNA.

172 of the RRE by the viral Rev protein induces nuclear export of RRE-containing RNAs, as required for v

173 T368 phosphorylation promoted nuclear export of SENP2, leading to downregulation of eN

174 However, how the nuclear export of Smad1/5/8 is regulated remains unclear

175 We propose that GANP promotes the nuclear export of specific classes of mRNAs that may fac

176 ere we show that PB components assist in the nuclear export of Ssd1and subsequent targeting of Ssd1 t

177 nhibition of NR4A1 nuclear export results in nuclear export of TGF-beta-induced beta-catenin, which t

178 cap-independent translation and inhibit the nuclear export of the 60S ribosomal subunit, respectivel

179 fine the division plane [5-8]; then, massive nuclear export of the anillin-like protein Mid1 at mitos

180 A recent study shows that nuclear export of the large ribosomal subunit is regulat

181 e breast cancer (TNBC) cells is dependent on nuclear export of the orphan receptor NR4A1, which plays

182 ndole-derived NR4A1 antagonists that inhibit nuclear export of the receptor and thereby block TGF-bet

183 h in turn phosphorylates NR4A1, resulting in nuclear export of the receptor.

184 nal regulators to activate transcription and nuclear export of the resulting messenger RNAs for cytop

185 slation of viral mRNAs, it also promotes the nuclear export of the viral late gene mRNAs by acting as

186 d arginine methyltransferase 1) promotes the nuclear export of these mRNAs by methylating the paraspe

187 CRM1 is involved in nuclear export of tumor suppressors such as p53.

188 The HIV-1 Rev protein activates nuclear export of unspliced and partially spliced viral

189 HIV replication requires nuclear export of unspliced and singly spliced viral tra

190 l step in viral replication by mediating the nuclear export of unspliced and singly-spliced viral mRN

191 recently reported that nuclear Naf1 promoted nuclear export of unspliced HIV-1 gag mRNA, leading to i

192 ht be an endogenous cellular process for the nuclear export of very large RNPs and protein aggregates

193 In human cells, hCRM1 regulates the nuclear export of viral intron-containing mRNAs through

194 clear export protein (NEP), required for the nuclear export of viral ribonucleoproteins and for timin

195 ains a sequence which supports the efficient nuclear export of viral RNAs, (ii) the cellular factor N

196 lymerase activity-enhancing property for the nuclear export of vRNPs.

197 ed HIV-1 transcripts for either Rev-mediated nuclear export or degradation.

198 (CDK) inhibitor p27/Kip1, and stimulates its nuclear export or exclusion.

199 on is dependent on the presence of an intact nuclear export pathway as c-Jun is stabilized and locali

200 Rev Response Element (RRE) through the Crm1 nuclear export pathway to the cytoplasm where viral prot

201 HIV-1 requires a specialized nuclear export pathway to transport unspliced and partia

202 d surprising parallels with a novel cellular nuclear export process.

203 s axon regeneration, whereas enhancing HDAC5 nuclear export promotes axon regeneration in vitro and i

204 ribonucleoproteins (RNPs) that had undergone nuclear export, promoting the formation of large perinuc

205 ding frames of nonstructural protein 1 (NS1)/nuclear export protein (NEP) for the modified NS segment

206 X (PA-X), Nonstructural Protein 1 (NS1), and Nuclear Export Protein (NEP) genes.

207 Intriguingly, the nuclear export protein (NEP) is involved in both process

208 essential for innate immune evasion, and the nuclear export protein (NEP), required for the nuclear e

209 s, the nonstructural protein 1 (NS1) and the nuclear export protein (NEP).

210 We also determine that Rph1 and nuclear export protein Crm1 interact, which is required

211 by exportin 1 (XPO1) interaction with viral nuclear export protein tethered to vRNP.

212 ng by binding to the catalytic groove of the nuclear export protein XPO1 (also known as CRM1, chromos

213 ioavailable, first-in-class inhibitor of the nuclear export protein XPO1, in this phase 1 trial to as

214 oral selinexor, a selective inhibitor of the nuclear export protein XPO1.

215 Expression of the nuclear export protein, Exportin 7 (Xpo7), is highly ery

216 nuclear export uses it to complement its own nuclear export proteins (a site not targeted by current

217 s newly synthesized viral proteins with host nuclear export proteins and stabilizes microtubule compl

218 Targeting nuclear export receptor (exportin 1 [XPO1]) is a novel a

219 the chromosomal region maintenance 1 (mCRM1) nuclear export receptor and rescued by the expression of

220 ponse element (RRE), to recruit the cellular nuclear export receptor Crm1 and Ran-GTP.

221 Nuclear export receptor CRM1 binds highly variable nucle

222 SET-Nup214 nuclear bodies containing the nuclear export receptor CRM1 were observed in the leukem

223 of both pre-tRNAs and U6 snRNA requires the nuclear export receptor Exportin-5.

224 somal region maintenance 1 (CRM1), the major nuclear export receptor for proteins.

225 The Nxf1 protein is a major nuclear export receptor for the transport of mRNA, and i

226 Here, we report the involvement of the nuclear export receptor NXF1/TAP in the nuclear export o

227 Chromosomal region maintenance 1 (CRM1) is a nuclear export receptor recognizing proteins bearing a l

228 Chemical perturbation of the nuclear export receptor XPO1 (also known as CRM1), with

229 some maintenance region-1 (CRM-1), the major nuclear export receptor.

230 le to the murine version of the CRM1 (mCRM1) nuclear export receptor.

231 findings challenge the current paradigm that nuclear export regulates the proteolysis of FOXO3A/4 tum

232 e splicing, RNA processing and modification, nuclear export, regulation of transcript stability, and

233 Inhibition of NR4A1 nuclear export results in nuclear export of TGF-beta-ind

234 ls for three major remodelling events before nuclear export: rotation of the 5S ribonucleoprotein, co

235 The selective inhibitor of nuclear export, selinexor, is in development for the tre

236 717-724 that bears strong homology to known nuclear export sequence (NES) domains.

237 th the addition of a nuclear localization or nuclear export sequence demonstrates that nuclear accumu

238 the nucleus, possibly due to disruption of a nuclear export sequence located downstream of the FERM-a

239 ility of hydrophobic residues (including the nuclear export sequence), providing a rationale for the

240 e RRE assembles a Rev oligomer that displays nuclear export sequences (NESs) for recognition by the C

241 into the cytoplasm requires two leucine-rich nuclear export sequences at the C-terminus.

242 impaired in +TIP-TORC1 interactions or Stu2 nuclear export show increased nuclear but not cytoplasmi

243 p27(KIP1) lacks a nuclear export signal (NES) and requires an adaptor for

244 Furthermore, we identified a nuclear export signal (NES) at the N terminus (AAs 176-1

245 xclusively by nuclear exclusion, driven by a nuclear export signal (NES) that restricts GEN1 actions

246 rtite nuclear localization signal (bNLS) and nuclear export signal (NES), as well as to a fluorescent

247 The nuclear export signal (NES)-binding groove of CRM1 is ab

248 ild-type (wt) SOD1 exposes a normally buried nuclear export signal (NES)-like sequence.

249 l nuclear localization signal and C-terminal nuclear export signal (NES).

250 activity of Rev's prototypical leucine-rich nuclear export signal (NES).

251 ophagy (Atg3) or recombinant NIC tagged to a nuclear export signal (NIC-NES), restored autophagy and

252 because deletion of the NLS or addition of a nuclear export signal abolished its HR-inducing ability.

253 but only HDAg-L contains a CRM1-independent nuclear export signal at its C terminus.

254 ng site is highly conserved within the first nuclear export signal consensus sequence identified in S

255 a functional role by enhancing access to the nuclear export signal contained within its sequence.

256 from the nucleus during interphase using the nuclear export signal in Alp14 but is accumulated in the

257 localization signals in XLG2 and XLG3 and a nuclear export signal in XLG3, which may facilitate intr

258 The nuclear export signal of AR (NES(AR)) has an important r

259 Deletion of the nuclear export signal of CHK1 led to its hyperphosphoryl

260 endent phosphorylation of Stu2 adjacent to a nuclear export signal prevents nuclear accumulation of S

261 in a leucine-rich stretch, which resembles a nuclear export signal, and could be inactivated by site-

262 ed to the cytoplasm employing a heterologous nuclear export signal, it is expressed at very low level

263 a cellular karyopherin-beta that transports nuclear export signal-containing proteins from the nucle

264 recognizing proteins bearing a leucine-rich nuclear export signal.

265 h leptomycin B and was dependent on an Mypt1 nuclear export signal.

266 ion signal, a nuclear retention domain and a nuclear export signal.

267 Moreover, induced expression of the nuclear exporting signal (NES)-fused form of Rb caused d

268 hat CD151 is a critical novel host factor of nuclear export signaling whereby the IAV nuclear export

269 its DNA binding domain and two leucine-rich nuclear export signals (NES) in its ligand binding domai

270 Classical nuclear export signals (NESs) are short cognate peptides

271 r export receptor CRM1 binds highly variable nuclear export signals (NESs) in hundreds of different c

272 rt of diverse cargos containing leucine-rich nuclear export signals (NESs) through complex formation

273 eds of proteins through recognition of their nuclear export signals (NESs), which are highly variable

274 sults suggest a model wherein Rev-associated nuclear export signals cooperate to regulate the number

275 ed to YFP and either nuclear localization or nuclear export signals in N benthamiana showed that cell

276 ormation and reveal how the binding site for nuclear export signals of cargoes is modulated by differ

277 Prp40 possesses two leucine-rich nuclear export signals, but little is known about the fu

278 ce region 1 (CRM1) by Selective Inhibitor of Nuclear Export (SINE) compounds results in reversal of E

279 lable small-molecule selective inhibitors of nuclear export, specifically, the XPO1 antagonist KPT-33

280 ation of pre-mRNAs is critical for efficient nuclear export, stability, and translation of the mature

281 remodeling complex as an unanticipated mRNP nuclear export surveillance factor that retains export-i

282 tion of HDAC4 at Ser(246) and preventing its nuclear export that leads to cytoplasmic degradation of

283 , 11, 21, and 27) demonstrated inhibition of nuclear export through a covalent addition at Cys528 of

284 inexor blocks progeny influenza virus genome nuclear export, thus effectively inhibiting virus replic

285 CstF64- and PABPN1-mediated coupling of mRNA nuclear export to 3' processing.

286 of nuclear export signaling whereby the IAV nuclear export uses it to complement its own nuclear exp

287 s inhibited through suppression of p120ctn's nuclear export using leptomycin-B.

288 Nuclear export was blocked using leptomycin B, suggestin

289 ng showed that half of the transcripts whose nuclear export was impaired following NXF1 depletion als

290 defect in intronless hemagglutinin (HA) mRNA nuclear export was seen with an NS1 mutant virus.

291 amics of selinexor, a selective inhibitor of nuclear export, when combined with fludarabine and cytar

292 treatment with leptomycin B, an inhibitor of nuclear export, whereas fusion of this domain to a heter

293 gh levels of Paf1 on Pol2 promote transcript nuclear export, whereas low levels reflect nuclear reten

294 t the Nup214 parts mediate the inhibition of nuclear export, whereas the SET or SQSTM1 part determine

295 in release of AR from HSP90, suppression of nuclear export which otherwise dominates over import and

296 factors are required for mRNA biogenesis and nuclear export, which are central to the eukaryotic gene

297 ions and kinetic rates for receptor-mediated nuclear export, which further exhibit an unexpected pseu

298 uclear levels of HDAC5 in UMR106 by blocking nuclear export with leptomycin B (LepB) or overexpressio

299 (NPCs) and, in addition to integrating mRNA nuclear export with preceding steps in the gene expressi

300 ubnuclear transport of vRNP, abolishing vRNP nuclear export without affecting viral RNA or protein ex