ライフサイエンスコーパス: nuclear foci

1 th paraspeckle protein NonO to form residual nuclear foci.

2 the accumulation of gamma-H2AX and 53BP1 in nuclear foci.

3 located in proximity to H3 K79 dimethylation nuclear foci.

4 ther viral DNA replication proteins in large nuclear foci.

5 ination of FANCD2 and the assembly of FANCD2 nuclear foci.

6 ted, SSBP2 remains associated with E1B55K in nuclear foci.

7 L1 that is sequestered in the CUG-containing nuclear foci.

8 domain also promotes ssDNA but fails to form nuclear foci.

9 e modifier (SUMO)-1 conjugates into distinct nuclear foci.

10 ith PCNA (early) and RPA2 (late) in discrete nuclear foci.

11 H2AX became phosphorylated and formed nuclear foci.

12 d NBS1) underwent phosphorylation and formed nuclear foci.

13 on and the formation of gamma-H2AX and 53BP1 nuclear foci.

14 FANCD2, targeting FANCD2 to BRCA1-containing nuclear foci.

15 videnced by induction of gammaH2AX and 53BP1 nuclear foci.

16 ction, and localized the protein to punctate nuclear foci.

17 h SMRT results in colocalization at discrete nuclear foci.

18 ese proteins colocalized to several distinct nuclear foci.

19 AtSIZ1-GFP was localized to nuclear foci.

20 and the assembly of damage-associated FANCD2 nuclear foci.

21 PA and Mre11 to discrete detergent-resistant nuclear foci.

22 n the nucleoplasm, R288P Maf was enriched in nuclear foci.

23 as well as other interaction partners to the nuclear foci.

24 FANCD2, resulting in the assembly of FANCD2 nuclear foci.

25 association with ionizing radiation-induced nuclear foci.

26 nd photoperiodic pathways in transcriptional nuclear foci.

27 .nibrin complex relocalizes to form punctate nuclear foci.

28 pathogenic RNA molecules that accumulate in nuclear foci.

29 DR machinery colocalized with LT in distinct nuclear foci.

30 zes with BRCA1 and RAD51 in S-phase-specific nuclear foci.

31 radiation (IR), 53BP1 localized at discreet nuclear foci.

32 resulting in targeting of this protein into nuclear foci.

33 lization pattern and is enriched in specific nuclear foci.

34 p220 is localized to discrete nuclear foci.

35 ludes the sequestration of many factors into nuclear foci.

36 -Thr68 phosphorylation and accumulation into nuclear foci.

37 The pathogenic RNA is retained in nuclear foci.

38 DDR pathways accumulate in MCPyV LT-positive nuclear foci.

39 d protein phosphorylation that generates sub-nuclear foci.

40 sequesters PTIP away from radiation-induced nuclear foci.

41 diverse membrane compartments as well as in nuclear foci.

42 rotein, these activities became localized to nuclear foci.

43 ed activation of caspase 3, and reduction of nuclear foci.

44 A to form spontaneous and DNA damage-induced nuclear foci.

45 P1- and phospho-H2AX (gamma-H2AX)-containing nuclear foci, a marker of DNA damage.

46 ence of BRCA1, FANCJ colocalizes with RPA in nuclear foci after DNA damage.

47 uired for recruitment of repair factors into nuclear foci after DNA damage.

48 irect immunofluorescence and formed discrete nuclear foci after exposure to IR, UV radiation, and hyd

49 e, does not support localization of Rad51 to nuclear foci after exposure to UV or treatment with ioni

50 xth, FANCD2, which colocalizes with BRCA1 in nuclear foci after genotoxic stress.

51 RPA protein inhibited the formation of RAD51 nuclear foci after hydroxyurea-induced replication stall

52 pol mu also forms discrete nuclear foci after IR, and these foci are largely coinci

53 uired for the assembly or stability of XRCC1 nuclear foci after oxidative DNA damage and suggest that

54 ein XRCC1 is rapidly assembled into discrete nuclear foci after oxidative DNA damage at sites of poly

55 efective for the formation of ATR-containing nuclear foci after UV irradiation, suggesting that hMCM7

56 otifs are also required for Polkappa to form nuclear foci after UV radiation.

57 the accumulation of replication protein A in nuclear foci, an indication that Vpr likely induces stal

58 BLM, the gene mutated in BS, is localized in nuclear foci and absent from BS cells.

59 damage response factors Rfa1 and Mre11 into nuclear foci and activation of the Rad53 DNA damage chec

60 ted region (3'-UTR) transcripts aggregate in nuclear foci and are thought to impose dominant-negative

61 ocalizes with ARGONAUTE 4 (AGO4) in punctate nuclear foci and binds AGO4 and RNA transcripts.

62 odes a zinc finger protein that localizes to nuclear foci and binds the promoters of let-60/RAS, lin-

63 scopy-based screening for proteins that form nuclear foci and characterized their localizations using

64 Phosphorylated FANCE assembles in nuclear foci and colocalizes with FANCD2.

65 Mms22 forms spontaneous nuclear foci and colocalizes with Rad22 in cells treated

66 The toxic RNA typically aggregates into nuclear foci and contributes to disease pathogenesis.

67 olongs the resolution of gammaH2AX and Rad51 nuclear foci and delays DNA repair.

68 ired for the recruitment of p53 into MLL-ELL nuclear foci and is both necessary and sufficient for th

69 nding motif that localizes TAZ into discrete nuclear foci and is essential for TAZ-stimulated gene tr

70 ATRX accumulates in nuclear foci and is required for therapy-induced senesce

71 This (iCUG)480 transcript accumulates in nuclear foci and its expression leads to muscle wasting

72 The localization of TREX in nuclear foci and its loading on piRNA precursor transcri

73 ed (ATR) kinase and poleta accumulation into nuclear foci and localization to individual telomeres, c

74 TopBP1 forms nuclear foci and localizes to the sites of DNA damage or

75 This complex forms nuclear foci and may be a sensor of double-strand breaks

76 inhibition and DNA damage by relocalizing to nuclear foci and physically associating with CCT, sugges

77 ctivation, formation of the NBS1/Mrel1/Rad50 nuclear foci and rescue of hypersensitivity to ionizing

78 ral papillomavirus types localize to defined nuclear foci and result in growth suppression of the hos

79 Moreover, recruitment of Ddc2 to nuclear foci and subsequent activation of the Rad53 kina

80 chromatin-bound BRCA2 colocalizes with BCCIP nuclear foci and that most radiation-induced RAD51 foci

81 the BLM helicase activity but abolished BLM nuclear foci and the association of BLM with condensed D

82 onstrate that Sall1 is localized to discrete nuclear foci and this localization depends on the N-term

83 R clones could form DNA-damage-induced RAD51 nuclear foci and were able to limit genotoxin-induced ge

84 east cancer susceptibility protein 1 (BRCA1) nuclear foci, and a C-terminal domain is required for Vp

85 ation during the cell cycle, localization to nuclear foci, and interaction with Brca1 and Rad51.

86 stress, Mex67 does not localize to the Mlp1 nuclear foci, and its association with Nab2 complexes is

87 Most Hd protein is found in nuclear foci, and some may traverse the nuclear envelope

88 scle nucleoplasm because of sequestration in nuclear foci, and the associated splicing defects are re

89 lar proteins are present in E1-E2-containing nuclear foci, and the viral origin of replication is req

90 gamma-H2AX and 53BP1 (p53 binding protein 1) nuclear foci, and this induction was heightened in FA-de

91 tion is a critical event required for Fancd2 nuclear foci assembly, release from chromatin, and funct

92 5) phospho-p53, BLM, and RAD51 colocalize in nuclear foci at sites likely to contain DNA replication

93 Chk2 phosphorylated at Thr-68 is found in nuclear foci at sites of DNA damage (1).

94 lation on Ser(139) (gamma-H2AX), which forms nuclear foci at sites of DNA damage.

95 tributes in cells from cytoplasm to discrete nuclear foci at sites of DNA double-strand breaks.

96 horylated histone H2AX (gamma-H2AX) in large nuclear foci at sites of stalled replication forks.

97 e DNA double-strand break (DSB) repair, form nuclear foci at the Ch region in the G1 phase of the cel

98 reatment and co-localizes with H2AX, forming nuclear foci at the site of DNA damage.

99 response to DNA damage, BRCA1 relocalizes to nuclear foci at the sites of DNA lesions.

100 e and replication blocks by forming distinct nuclear foci at the sites of stalled replication forks.

101 lized with RNA polymerase II (RNA Pol II) in nuclear foci, bound to histone H2B, and deubiquitylated

102 BRCA1 exists in nuclear foci but is hyperphosphorylated and disperses af

103 ted ATM, hypoxia-activated ATM does not form nuclear foci but is instead diffuse throughout the nucle

104 CA1 interact and co-localize within discrete nuclear foci but separate after gamma irradiation.

105 finger (UBZ) domain directs human WRNIP1 to nuclear foci, but the functional significance of its pre

106 A significant fraction of the hTDG nuclear foci co-localize with hRad9 foci in cells treate

107 A significant fraction of the hNEIL1 nuclear foci co-localize with hRad9 foci in hydrogen per

108 We find that FANCD2 nuclear foci colocalize with telomeres and PML bodies in

109 f the FANCD2 protein and formation of FANCD2 nuclear foci confirmed the activation of the pathway by

110 lectrophoresis or by formation of gamma-H2AX nuclear foci, considered the most sensitive assay for DN

111 2 to 1%) contained large, intensely staining nuclear foci consistent with productive, replicative inf

112 lowed us to visualize replication factories, nuclear foci consisting of replication proteins where th

113 MCPyV sT translocates to nuclear foci containing actively replicating viral DNA,

114 resulting in the redistribution of FANCD2 to nuclear foci containing BRCA1.

115 e downstream FANCD2 protein and targeting to nuclear foci containing BRCA1.

116 1 (HSV-1) induces the formation of discrete nuclear foci containing cellular chaperone proteins, pro

117 ) cell cycle arrest through the induction of nuclear foci containing gamma-H2AX and BRCA1.

118 Finally, we find that c-Jun associates with nuclear foci containing gammaH2AX and ATM following irra

119 histone 2A variant X (H2AX) and formation of nuclear foci containing H2AX and breast cancer susceptib

120 ells assemble the amyloid bodies (A-bodies), nuclear foci containing heterogeneous proteins with amyl

121 or mitomycin C (MMC) led to the formation of nuclear foci containing phosphorylated Nbs1.

122 f activated forms of ATM and Chk2 as well as nuclear foci containing phosphorylated substrates of ATM

123 uorescent protein-polkappa fusion protein to nuclear foci containing sites of active DNA synthesis in

124 xogenous pri-miRNAs unexpectedly localize to nuclear foci containing splicing factor SC35; yet these

125 Nuclear foci corresponding to epigenetic marks as well a

126 ly expressed RGS12TS-S localized to discrete nuclear foci (dots), a characteristic of various tumor s

127 in response to DNA damage and is targeted to nuclear foci (dots).

128 nally, ATR activation and its recruitment to nuclear foci during cisplatin treatment were attenuated,

129 DNA processes, Mms22p localizes to discrete nuclear foci, even in the absence of etoposide or its bi

130 quitination of FANCD2 or its localization to nuclear foci following DNA damage.

131 CA1 function, such as BRCA1 association with nuclear foci following DNA damage.

132 is domain of ATM is required for ATM to form nuclear foci following exposure to ionizing radiation.

133 endent BRCA2 S3291 phosphorylation and MRE11 nuclear foci formation and can be rescued by inhibition

134 Disruption of BTB dimerization abrogates nuclear foci formation and telomeric localization of not

135 to repair double strand breaks is inducible nuclear foci formation at the sites of damage.

136 placed by phenylalanine, exhibit compromised nuclear foci formation in response to IR.

137 Furthermore, IR-induced Rad52 nuclear foci formation is markedly suppressed by the exp

138 Monoubiquitination and nuclear foci formation of FANCD2 are critical steps of t

139 The monoubiquitination and nuclear foci formation of FANCD2 are essential for the f

140 CC complex formation, monoubiquitination and nuclear foci formation of FANCD2, and mitomycin C resist

141 d PSMB3) inhibited monoubiquitination and/or nuclear foci formation of FANCD2, whereas depletion of D

142 ibitors, whereas ATM autophosphorylation and nuclear foci formation of gammaH2AX, MDC1, and RPA were

143 e show that RNF8 controls DNA damage-induced nuclear foci formation of PTIP, which in turn regulates

144 (IR) induces the phosphorylation of NBS1 and nuclear foci formation of the complex.

145 evec, radiation-induced Rad51 expression and nuclear foci formation were reduced.

146 romosomal aberrations and elevated gammaH2AX nuclear foci formation.

147 ge-inducible FANCD2/I monoubiquitination and nuclear foci formation.

148 rthermore, ATR nuclear foci overlap with the nuclear foci formed by BRCA1.

149 t also resulted in the colocalization of the nuclear foci formed with RecQ4 and xeroderma pigmentosum

150 s also resulted in the colocalization of the nuclear foci formed with the two complexes.

151 Two compounds that reduce and/or remove nuclear foci have been identified, Ro 31-8220 and chromo

152 oteins at the nuclear periphery, or in other nuclear foci, have also been identified.

153 We found that UBR5 forms damage-inducible nuclear foci in a manner dependent on the PRC1 component

154 ow that UvsC(RAD51) forms DNA-damage-induced nuclear foci in a manner that requires SepB function.

155 etect a 220-kD protein localized in discrete nuclear foci in all epithelial cell lines, including tho

156 f human breast specimens also revealed BRCA1 nuclear foci in benign breast, invasive lobular cancers

157 anded CUG repeats in vitro, localized to the nuclear foci in both DM1 and DM2.

158 C (G2C4) repeat-expansion RNAs accumulate in nuclear foci in brain.

159 localization of PALB2 and BRCA2 to RPA-bound nuclear foci in cells experiencing replication stress.

160 ulate in MCPyV large T antigen (LT)-positive nuclear foci in cells infected with native MCPyV virions

161 of the complex and induces the formation of nuclear foci in cells on DNA damage.

162 A, is mounted upon the nuclear matrix in sub-nuclear foci in differentiated vertebrate cells, but not

163 otypic assay, based on the identification of nuclear foci in DM patient cell lines using in situ hybr

164 ions of MBNL, MBLL and MBXL co-localize with nuclear foci in DM1 and DM2 cells, suggesting that all t

165 ntiation, but the EXP proteins accumulate in nuclear foci in DM1 cells.

166 e-labeled CAG-repeat oligonucleotides showed nuclear foci in DM2 similar to those seen in DM1.

167 We show that ATR is recruited to IR-induced nuclear foci in G(1) and S phase of the cell cycle, supp

168 e its fly counterpart, hp53 formed prominent nuclear foci in germline cells but cancer-associated p53

169 e also demonstrate that FANCI forms discrete nuclear foci in HeLa cells in the absence or presence of

170 binds BRC repeats and forms BRCA2-dependent nuclear foci in human cells in response to gamma-irradia

171 w that TRIP promotes hPoleta localization to nuclear foci in human cells.

172 related with a significant increase in yH2AX nuclear foci in Mof-deficient MLL-AF9 tumor cells.

173 BRD4-NUT forms distinctive nuclear foci in patient tumors, which we found correlate

174 36 depletion prevents the formation of BRCA1 nuclear foci in response to DNA damage in breast cancer

175 comes hyperphosphorylated and forms discrete nuclear foci in response to DNA damage.

176 The rapid accumulation of BRCA1 into nuclear foci in response to induction of DNA breaks sugg

177 t phosphorylate p53 in vivo and did not form nuclear foci in response to ionizing radiation.

178 )-phosphorylated form of Chk2 forms distinct nuclear foci in response to ionizing radiation.

179 ernal repeats and is an early participant in nuclear foci in response to IR.

180 cells leads to loss of Rad51 localization to nuclear foci in response to replication arrest, cells la

181 nctionally in human cells and co-localize to nuclear foci in response to replication stress.

182 We found that senataxin forms distinct nuclear foci in S/G(2)-phase human cells and that the nu

183 mplex chromosome aberrations, and lack Rad51 nuclear foci in the presence of DNA-damaging agents, suc

184 raction enhances the recruitment of 53BP1 to nuclear foci in the S phase, resulting in impaired HR an

185 Moreover, BLM and WRN colocalized to nuclear foci in three human cell lines.

186 localization pattern but also forms distinct nuclear foci in unperturbed growing and G(2)/M-arrested

187 alization of endogenous CBP/p300 proteins to nuclear foci in vivo.

188 Immunostaining shows that RPA localizes to nuclear foci in Vpr-expressing cells.

189 truct resulted in the appearance of discrete nuclear foci in which TdT and Ku colocalize.

190 Fluorescence of nuclear foci increased during the first hour of stimulat

191 processing redistributes GANP from NPCs into nuclear foci indicating that mammalian TREX-2 is associa

192 o the nucleus, and enhances formation of the nuclear foci indicative of recombination sites.

193 dogenous Brca1-Delta11 localizes to discrete nuclear foci indistinguishable from those found in wild-

194 G1, ectopically expressed HDHB localizes in nuclear foci induced by DNA damaging agents and that thi

195 pathways and that ionizing radiation-induced nuclear foci (IRIF) of NFBD1 colocalize with several DNA

196 lian 53BP1, forms ionizing radiation-induced nuclear foci (IRIF).

197 Rad3(ATR), forms ionizing radiation-induced nuclear foci (IRIF).

198 RAD51 and BRCA2 colocalization in nuclear foci is a hallmark of HRR.

199 Accumulation of expanded poly(CUG) RNA in nuclear foci is associated with sequestration of muscleb

200 active tuning of BRCA1 activity, executed in nuclear foci, is important to genome integrity maintenan

201 51 protein, manifested as formation of Rad51 nuclear foci, is seen upon IR treatment.

202 n that colocalizes with cellular proteins in nuclear foci known as Tax speckled structures (TSS).

203 tein kinase (DMPK) transcripts accumulate in nuclear foci, leading to abnormal regulation of RNA proc

204 completion because these markers persist as nuclear foci long after drug removal.

205 Immunofluorescence staining reveals discrete nuclear foci of ANCO-1 that are distinct from known nucl

206 CAG25 disperses nuclear foci of CUGexp RNA and reduces the overall burde

207 lve sequestration of RNA binding proteins in nuclear foci of expanded poly(CUG) RNA.

208 Formation of nuclear foci of FANCD2 was normal in the BRCA2 mutant CA

209 hat calcitriol induces formation of multiple nuclear foci of heterodimers.

210 nhibitors and ionomycin caused appearance of nuclear foci of NFATc-GFP without electrical stimulation

211 Moreover, we quantified cardiomyocyte nuclear foci of phosphorylated ataxia telangiectasia mut

212 These markers include nuclear foci of phosphorylated histone H2AX and their co

213 with an increased number of cells exhibiting nuclear foci of phosphorylated histone H2AX as well as a

214 In addition, UV-induced nuclear foci of the recombination proteins, RAD51 and BR

215 These effects correlate with increased nuclear foci of the single-stranded DNA binding protein

216 o found that these progeroid cells exhibited nuclear foci of xeroderma pigmentosum group A (XPA), a u

217 ey affect neither the assembly of Rad51 into nuclear foci on damaged DNA nor DNA repair by HR.

218 UV-exposed cells did not exhibit FANCD2 nuclear foci once they entered mitosis or when growth-ar

219 ique pattern of subnuclear organization into nuclear foci or dots when expressed endogenously or ecto

220 efects cause mRNAs to accumulate in discrete nuclear foci or dots, in mammalian cells as well as yeas

221 sociation and did not redistribute Poleta to nuclear foci or promote Poleta-PCNA interaction efficien

222 of the expanded repeat (r(GGGGCC)exp) forms nuclear foci or undergoes repeat-associated non-ATG (RAN

223 ll showed diffuse nuclear staining, multiple nuclear foci, or one or two larger bodies confined to th

224 r the initial disruption of ND10 and display nuclear foci, or prereplicative sites, containing the vi

225 cells is a defect in the targeting of SMN to nuclear foci; our results uncover a role for coilin in t

226 Furthermore, ATR nuclear foci overlap with the nuclear foci formed by BRC

227 produced a large increase of CUG(exp) RNA in nuclear foci, owing to reduced turnover of the CUG(exp)

228 ed by phosphorylation, displays a BRCA1-like nuclear foci pattern and colocalizes with gamma-H2AX.

229 e gamma-H2AX apoptotic ring differs from the nuclear foci patterns observed in response to DNA-damagi

230 ins ZNF423, CEP164, and NPHP10 colocalize to nuclear foci positive for TIP60, known to activate ATM a

231 GGGGCC)n-containing transcripts aggregate in nuclear foci possibly sequestering repeat-binding protei

232 GGCCCC)n-containing transcripts aggregate in nuclear foci, possibly sequestering repeat-binding prote

233 PALB2 colocalizes with BRCA2 in nuclear foci, promotes its localization and stability in

234 romote HR concentrate together with BRCA1 in nuclear foci, RAP80/BRCA1 complexes suppress excessive D

235 We show that the same compound eliminates nuclear foci, reduces MBNL1 protein in the nucleus, affe

236 the removal of DNA damage-induced gammaH2AX nuclear foci, reduces RAD51 nuclear focus formation and

237 BLM localizes to nuclear foci referred to as PML nuclear bodies (NBs).

238 We found that RecQ4 formed discrete nuclear foci specifically in response to UV irradiation

239 ointegrator complex) relocalizes to distinct nuclear foci specifically upon exposure of cells to alky

240 lators accomplish this task by forming dense nuclear foci termed insulator bodies that result from th

241 stimulates p53 activity by recruiting it to nuclear foci termed PML nuclear bodies.

242 at endogenous ataxin-7 localizes to discrete nuclear foci that also contain additional components of

243 ion of FANCD2, resulting in its targeting to nuclear foci that also contain BRCA1 and BRCA2/FANCD1, p

244 dependent manner, and rapidly relocalizes to nuclear foci that also contain the MRE11 complex, phosph

245 hat BRD4-NUT and BRD4 colocalize in discrete nuclear foci that are hyperacetylated but transcriptiona

246 radiation, CENP-A is found in multiple small nuclear foci that are mutually exclusive to gammaH2AX as

247 Unmodified forms of Hsp27 are localized in nuclear foci that are outside of replication compartment

248 ure to ionizing radiation, PTIP localizes to nuclear foci that are sites of DNA damage and repair.

249 Phosphorylated TDP1 forms nuclear foci that co-localize with those of phosphorylat

250 iated protein that forms irradiation-induced nuclear foci that colocalize with gamma-H2AX foci.

251 induced stalled replication forks by forming nuclear foci that colocalize with gamma-H2AX within 2 ho

252 totic cells, detects Cyclin E/Cdk2-dependent nuclear foci that colocalize with nascent histone transc

253 eloping thymocytes, NBS1 and gamma-H2AX form nuclear foci that colocalize with the T cell receptor al

254 aging agents, RAP80 translocates to discrete nuclear foci that colocalize with those of gamma-H2AX.

255 uorescence, pol epsilon appeared in discrete nuclear foci that colocalized with proliferating cell nu

256 inutes after gamma-irradiation, NFBD1 formed nuclear foci that colocalized with the phosphorylated fo

257 ion of BRCA1 and causes its recruitment into nuclear foci that contain DNA repair proteins.

258 microscopy that Tax forms damage-independent nuclear foci that contain DNA-PK, BRCA1, and MDC1.

259 in homologous DNA recombination to distinct nuclear foci that contain HPV genomes and cellular repli

260 RAD50-MRE11-NBS1 complex colocalize to large nuclear foci that contain PCNA when cells are treated wi

261 HR)-type DSB repair, concentrate at distinct nuclear foci that demarcate sites of genome breakage.

262 ospho-ser15-p53 in hydroxyurea-induced RAD51 nuclear foci that may correspond to the sites of presume

263 nd piRNA clusters and colocalize in distinct nuclear foci that overlap with sites of piRNA transcript

264 in Tax that targets the protein to discrete nuclear foci that we have previously termed Tax speckled

265 Unexpectedly, Mlh1-Pms1 formed nuclear foci that, although dependent on Msh2-Msh6 for f

266 ntranuclear relocalization, translocating to nuclear foci thought to represent sites of DNA damage an

267 calization patterns, ranging from bright sub-nuclear foci to almost exclusively cytoplasmic localizat

268 The repeat-bearing transcripts accumulate in nuclear foci, together with proteins in the muscleblind

269 Anumber of proteins are recruited to nuclear foci upon exposure to double-strand DNA damage,

270 RNA polymerase II nor the formation of Hsc70 nuclear foci was observed during infection with the phos

271 mation of green fluorescent protein-polkappa nuclear foci was temporally coincident with checkpoint-m

272 ATM and H2AX phosphorylation and gammaH2AX nuclear foci were also induced by UV-inactivated KSHV, w

273 Furthermore, DNA damage-induced Rad17 nuclear foci were dramatically reduced in Ppp5-deficient

274 Nuclear foci were present in all patients with symptomat

275 HomeoRR and RAD51 nuclear foci were strongly reduced by RAD51(Y315F) phosp

276 ation of the FANCD2 protein, targeting it to nuclear foci where it co-localizes with FANCD1/BRCA2, RA

277 n coincides with PGC-1beta redistribution to nuclear foci where it co-localizes with GCN5.

278 d in response to DNA damage, targeting it to nuclear foci where it preserves chromosomal integrity.

279 This expanded RNA is retained in nuclear foci where it sequesters and induces alterations

280 TR and RPA translocate to punctate, abundant nuclear foci where they continue to colocalize.

281 oteins, targeting these proteins to discrete nuclear foci where they function in DNA repair.

282 2 and FANCI localize in chromatin-associated nuclear foci where they interact with several well-chara

283 ssociated with C/EBPdelta translocation from nuclear foci, where C/EBPdelta co-localizes with p300, t

284 se nuclear distribution to discrete punctate nuclear foci, where E2F1 colocalized with TopBP1 and BRC

285 Ub), signaling its translocation to discrete nuclear foci, where it co-localizes with the central DNA

286 t FAZF and wild-type FANCC can colocalize in nuclear foci, whereas a patient-derived mutant FANCC tha

287 ax with Mxi1, Mad3, or Mad4 were enriched in nuclear foci, whereas complexes formed with Myc were mor

288 ontaining expanded CUG repeats (CUG(exp)) in nuclear foci which sequester several factors regulating

289 ve BPLF1 caused relocalization of Rad18 into nuclear foci, which is consistent with sites of cellular

290 Nbs1 (MRN) complex were found in distinct E2 nuclear foci, which peaked during mid-S phase, indicatin

291 se to DNA damage, Crb2 localizes to distinct nuclear foci, which represent sites of DNA double-strand

292 GANT61 induced gammaH2AX nuclear foci, while transient transfection of Gli3R show

293 from human cells, and FANCG co-localized in nuclear foci with both BRCA2 and RAD51 following DNA dam

294 phosphorylation, Nab2 and Yra1 colocalize in nuclear foci with Mlp1, a protein involved in mRNA reten

295 Rhino colocalizes to germline nuclear foci with Rai1/DXO-related protein Cuff and the

296 The FANCD2 protein co-localizes in nuclear foci with the BRCA1 protein following DNA damage

297 axia syndrome, and show that these RNAs form nuclear foci with unexpected morphological plasticity th

298 reveals that gamma-H2AX appears as discrete nuclear foci within 1 min after exposure of cells to ion

299 NFBD1 associates with nuclear foci within minutes following IR, a property sim

300 are identified that reduce GGGGCC-containing nuclear foci without altering overall C9orf72 RNA levels