ライフサイエンスコーパス: nuclear hormone receptor

1 thesis of ligands that inhibit the DAF-12, a nuclear hormone receptor.

2 oform a, suggesting an anabolic role for the nuclear hormone receptor.

3 juba as a unique corepressor for a subset of nuclear hormone receptors.

4 esylation, can act as an agonist for several nuclear hormone receptors.

5 aracteristic of coactivators/corepressors of nuclear hormone receptors.

6 ax lethal toxin (LeTx) selectively represses nuclear hormone receptors.

7 tional repression complexes recruited by the nuclear hormone receptors.

8 ation by SHP is dependent on the presence of nuclear hormone receptors.

9 LBPs is to deliver small-molecule ligands to nuclear hormone receptors.

10 with inactivation of repression mediated by nuclear hormone receptors.

11 gand-dependent transcriptional activation by nuclear hormone receptors.

12 t suggests a new paradigm for this family of nuclear hormone receptors.

13 ds to and influences the activity of several nuclear hormone receptors.

14 se in O-GlcNAc levels inhibits activation of nuclear hormone receptors.

15 re members of the family of ligand-dependent nuclear hormone receptors.

16 also shed light on the natural evolution of nuclear hormone receptors.

17 of metazoan transcription factors, including nuclear hormone receptors.

18 ptors (PPAR) are members of a superfamily of nuclear hormone receptors.

19 the clinical efficacy of agents that target nuclear hormone receptors.

20 led an evolutionarily conserved template for nuclear hormone receptors.

21 g delivery to tumor cells with overexpressed nuclear hormone receptors.

22 homeostatic processes that are controlled by nuclear hormone receptors.

23 s transcription by thyroid hormone and other nuclear hormone receptors.

24 e largely been credited to the activation of nuclear hormone receptors.

25 ceptors (RXRs) are important transcriptional nuclear hormone receptors, acting as either homodimers o

26 dynamics that drive this unusual PL-mediated nuclear hormone receptor activation.

27 been reported to be involved in influencing nuclear hormone receptor activities.

28 breast cancer cells with probe 4 attenuates nuclear hormone receptor activity mediated by retinoic a

29 ponent of the Mediator complex that controls nuclear hormone receptor activity, are repressed by miR-

30 he diversification of binding motifs for the nuclear hormone receptor and C2H2 zinc finger families a

31 rkers of the basal-like phenotype, including nuclear hormone receptor and HER2 negativity, cytokerati

32 These results indicate a link between nuclear hormone receptor and insulin signaling pathways,

33 r gamma (PPARgamma) belongs to the family of nuclear hormone receptors and consists of two isotypes,

34 d prevents these fatty acids from activating nuclear hormone receptors and driving fat-7 expression.

35 s (PPARs) (alpha, gamma, and delta/beta) are nuclear hormone receptors and ligand-activated transcrip

36 ctivator is a property shared with mammalian nuclear hormone receptors and likely allows greater tran

37 st metabolic genes via its interactions with nuclear hormone receptors and nuclear respiratory factor

38 r (NRC) is a 2,063-amino-acid coregulator of nuclear hormone receptors and other transcription factor

39 ochondrial biogenesis through stimulation of nuclear hormone receptors and other transcription factor

40 Mediator (MED) facilitates transcription of nuclear hormone receptors and other transcription factor

41 of TRAP/Mediator that targets the complex to nuclear hormone receptors and other types of activators.

42 of 0.7 nM with great selectivity over other nuclear hormone receptors and potently activated AR in a

43 we show that the direct interaction between nuclear hormone receptors and Prox1 is also necessary fo

44 s that logically explain the coordination of nuclear hormone receptors and the clock are poorly under

45 role of mammalian hADA3 as a coactivator of nuclear hormone receptors and the potential role of thes

46 nalysis will stimulate further research into nuclear hormone receptors and their associated transcrip

47 region in the ZnF_C4 signature motif of the nuclear hormone receptors and thus against the entire re

48 ative lipophilic hormone receptors, known as nuclear hormone receptors, and analyzed their functions

49 mplex relationships among the immune system, nuclear hormone receptors, and inflammation during regre

50 uch an analysis has been carried out for the nuclear hormone receptors, and the conclusions tested by

51 Mechanisms controlling nuclear hormone receptors are a central question to mamm

52 ligand-regulated transcription factors, the nuclear hormone receptors are nearly ideal drug targets,

53 Nuclear receptors (also known as nuclear hormone receptors) are hormone-regulated transcr

54 ole in mediating the effects of ligand-bound nuclear hormone receptors as well as other transcription

55 ies of transcriptional regulators, including nuclear hormone receptors, basic helix-loop-helix, ETS-

56 arly perfect direct repeats of the consensus nuclear hormone receptor binding element AGGTCA separate

57 PGC-1alpha differ in their interactions with nuclear hormone receptors but are highly similar in thei

58 essors contributes to specific regulation of nuclear hormone receptors by O-GlcNAc.

59 transcriptional efficacy of ligand activated nuclear hormone receptors by up to 8-fold in vitro and i

60 17 cell markers retinoic acid-related orphan nuclear hormone receptor c (RORc), IL-17A, and IL-23R.

61 pression of the retinoic acid-related orphan nuclear hormone receptor C and IL-17A and secretion of I

62 e inhibition of retinoic acid-related orphan nuclear hormone receptor C and IL-17A gene expression an

63 e expression of retinoic acid-related orphan nuclear hormone receptor C, a transcription factor that

64 g, in part through the local availability of nuclear hormone receptors called retinoic acid receptors

65 hat MED1 phosphorylation is required for its nuclear hormone receptor coactivator activity.

66 usly been demonstrated to associate with the nuclear hormone receptor coactivator AIB1/SRC-3, the que

67 The nuclear hormone receptor coactivator PGC-1 (peroxisome p

68 3 (SRC-3) is a histone acetyltransferase and nuclear hormone receptor coactivator, located on 20q12,

69 60 coregulators were initially identified as nuclear hormone receptor coactivators.

70 We demonstrate that dUTX binds to the nuclear hormone receptor complex Ecdysone Receptor/Ultra

71 ic Ecdysone receptor/Ultraspiracle (ECR/USP) nuclear hormone receptor complex throughout the entire n

72 significantly, the footprint sequences bind nuclear hormone receptor complexes in male, but not fema

73 ata are consistent with the possibility that nuclear hormone receptor complexes participate in the es

74 The nuclear hormone receptors comprise one of the largest cl

75 Nuclear hormone receptor coregulator (NRC) is a 2,063-am

76 ression of friend of GATA (FOG)-2, a cardiac nuclear hormone receptor corepressor protein.

77 Here we demonstrate that the nuclear hormone receptor Coup-TFII is necessary for the

78 We examined the role of the orphan nuclear hormone receptor CoupTFI in mediating cortical d

79 the FOXO transcription factor DAF-16 and the nuclear hormone receptor DAF-12 and influences metabolic

80 We show that the nuclear hormone receptor daf-12 is a let-7 target in sea

81 l timing and longevity through the conserved nuclear hormone receptor DAF-12, a homolog of mammalian

82 lifespan of C. elegans are controlled by the nuclear hormone receptor DAF-12, an important model for

83 lic hormone, which serves as a ligand to the nuclear hormone receptor DAF-12.

84 gulating the transcriptional activity of the nuclear hormone receptor DAF-12.

85 precursors that express RORgammat, an orphan nuclear hormone receptor detected only in immature CD4+C

86 We identified a nuclear hormone receptor, DHR96, as an essential mediato

87 cadian and major hormonal circuits involving nuclear hormone receptors display interlinked diurnal cy

88 Thus, induction of the PPARgamma nuclear hormone receptor during adipogenesis requires SW

89 s known about the expression of TRs or other nuclear hormone receptors during the cell cycle.

90 XA7 promoter identified a cluster of steroid nuclear hormone receptor elements, including V$GREF (V$G

91 lk" between a membrane receptor (CD44) and a nuclear hormone receptor (ER alpha) signaling pathway du

92 nhr-23 and nhr-25, genes encoding conserved nuclear hormone receptors essential for larval molting.

93 The nuclear hormone receptor estrogen receptor alpha (ERalph

94 We identified the orphan nuclear hormone receptor estrogen-related receptor beta

95 The nuclear hormone receptor, estrogen receptor alpha (ERalp

96 interact with the androgen receptor (AR), a nuclear hormone receptor expressed at high levels in Ser

97 ted basal-like differentiation and repressed nuclear hormone receptor expression after short-term PTE

98 d entry mechanism for members of the steroid nuclear hormone receptor family (androgen receptor, estr

99 oic acid receptors (RARs) are members of the nuclear hormone receptor family and regulate the prolife

100 d receptors (PPARs) and other members of the nuclear hormone receptor family are important drug targe

101 he androgen receptor (AR) is a member of the nuclear hormone receptor family of transcription factors

102 he androgen receptor (AR) is a member of the nuclear hormone receptor family of transcription factors

103 receptor-gamma (PPARgamma), a member of the nuclear hormone receptor family, is a master regulator o

104 farnesoid X receptor (FXR), a member of the nuclear hormone receptor family, plays important roles i

105 receptor gamma (PPARgamma), a member of the nuclear hormone receptor family, represents a possible n

106 n bisphenols and ERs or other members of the nuclear hormone receptor family, such as estrogen-relate

107 rogen receptor alpha (ER) is a member of the nuclear hormone receptor family, which upon binding estr

108 ay be easily adapted to other members of the nuclear hormone receptor family.

109 r prior studies with the bile acid-activated nuclear hormone receptor farnesoid X receptor (FXR) and

110 Bile acids are ligands for the nuclear hormone receptor farnesoid X receptor (FXR) and

111 Bile acids are ligands for the nuclear hormone receptor, farnesoid X receptor (FXR).

112 this study we demonstrate that the class II nuclear hormone receptor, farnesoid X-receptor (FXR), in

113 Here, we show that the nuclear hormone receptor for oxysterols, the liver X rec

114 A major challenge in understanding nuclear hormone receptor function is to determine how th

115 ated three dominant, X-linked mutants in the nuclear hormone receptor gene nhr-40 that are haploinsuf

116 nzalutamide via activation of an alternative nuclear hormone receptor, glucocorticoid receptor (GR),

117 ember of the p160 family of coactivators for nuclear hormone receptors, has been frequently detected

118 Numerous coactivators that bind nuclear hormone receptors have been isolated and charact

119 dermal ontogenesis is poorly understood, but nuclear hormone receptors have been shown to have an imp

120 Loss of the nuclear hormone receptor hepatocyte nuclear factor 4alph

121 The nuclear hormone receptors hepatocyte nuclear factor 4 (H

122 five footprinted areas contains at least two nuclear hormone receptor hexad binding sites arranged wi

123 d oxidation through its association with the nuclear hormone receptors HNF-4 and PPAR-alpha, respecti

124 expressed from lentiviruses and (3) that the nuclear hormone receptor HNF4A is essential for specific

125 We find that the SF1-related Drosophila nuclear hormone receptor HR39 is also essential for sexu

126 The NR5A-class nuclear hormone receptor Hr39 is essential for precursor

127 down expression after adult eclosion of the nuclear hormone receptor Hr39, a master regulator of gla

128 ell-described cotranscriptional activator of nuclear hormone receptors (i.e., Sp1), the hypothesis th

129 previously unrecognized role for this orphan nuclear hormone receptor in regulating STAT1 signaling a

130 s requires understanding the pivotal role of nuclear hormone receptors in lipid and inflammatory home

131 o explore the roles of dynamically expressed nuclear hormone receptors in molting, and to analyze mei

132 Our studies identify a role for nuclear hormone receptors in planarian reproductive matu

133 to potentiate transcriptional activation by nuclear hormone receptors in podocytes.

134 uggest a potential role for dysregulation of nuclear hormone receptors in the pathogenesis of ADPKD.

135 tion studies, and elucidation of the role of nuclear hormone receptors in the regulation of bile salt

136 amined the expression patterns of a panel of nuclear hormone receptors in these two cell lines and de

137 The superfamily of nuclear hormone receptors includes transcription factors

138 (also known as GPBAR1, M-BAR, and BG37) and nuclear hormone receptors including farnesoid X receptor

139 le cross-reactivity against a panel of human nuclear hormone receptors including PPARdelta.

140 ember of the p160 family of coactivators for nuclear hormone receptors including the androgen recepto

141 ow-density lipoprotein receptor (LOX-1); the nuclear hormone receptors, including peroxisome-prolifer

142 hormone receptors) interact with unliganded nuclear hormone receptors, including thyroid hormone (T(

143 are not available to cell surface receptors, nuclear hormone receptors, ion channels, transporters, a

144 Liver X receptor (LXR), a nuclear hormone receptor, is an essential regulator of i

145 dogenic factor SF-1, a constitutively active nuclear hormone receptor, is essential to the developmen

146 factor 4alpha (HNF4alpha), a liver-enriched nuclear hormone receptor, is markedly inhibited, whereas

147 though NIF-1 does not directly interact with nuclear hormone receptors, it enhances activation by nuc

148 binding site in the AKR1C4 promoter for the nuclear hormone receptor known as liver X receptor alpha

149 Small heterodimer partner (SHP), an orphan nuclear hormone receptor lacking a DNA binding domain, i

150 The two nuclear hormone receptor ligands progesterone and vitami

151 sitivity to estrogens, progestins, and other nuclear hormone receptor ligands.

152 The nuclear hormone receptor liver X receptor (LXR) is induc

153 Previously, we have shown that the nuclear hormone receptor liver X receptor-alpha (LXRalph

154 The nuclear hormone receptors liver X receptor alpha (LXRalp

155 nd genetic evidence establishing the liver-X nuclear hormone receptor (LXR) as a therapeutic target i

156 thesis in HepG2 cells suggests that multiple nuclear hormone receptors mediate viral replication in t

157 tion of the androgen receptor (AR) and other nuclear hormone receptor-mediated actions.

158 the development of BPA substitutes devoid of nuclear hormone receptor-mediated activity and more gene

159 raction identifies a site of convergence for nuclear hormone receptor-mediated and VSMC-specific gene

160 s Jmjd1a and Kdm3a) has an important role in nuclear hormone receptor-mediated gene activation and ma

161 eptor lacking a DNA binding domain, inhibits nuclear hormone receptor-mediated viral transcription an

162 soid X receptor (FXR), a bile acid-activated nuclear hormone receptor, modulates renal SREBP-1 expres

163 One of these proteins, the DAF-12 nuclear hormone receptor, modulates the transcription of

164 xpression during molting, likely through the nuclear hormone receptor NHR-23.

165 The Caenorhabditis elegans Nuclear Hormone Receptor NHR-49 coordinates expression o

166 occurs with precise timing, and requires the nuclear hormone receptor NHR-67.

167 , which promoted longevity by activating the nuclear hormone receptors NHR-49 and NHR-80.

168 pharyngeal muscles and is recognized by the nuclear hormone receptor (NHR) DAF-12.

169 lapping feedback loops that are modulated by nuclear hormone receptors (NHR), miRNAs, and epigenetic

170 er in controlling gene regulation in nature, nuclear hormone receptors (NHRs) have largely eluded uti

171 Nuclear hormone receptors (NHRs) regulate the expression

172 ted ion channels and, in a recent update, 49 nuclear hormone receptors (NHRs).

173 )) that solely disrupts its interaction with nuclear hormone receptors (NHRs).

174 ID) for detecting ligands that interact with nuclear hormone receptors (NHRs).

175 d hormone receptors (TRs) are members of the nuclear hormone receptor (NR) superfamily and regulate d

176 by inactivation of a photoreceptor-specific nuclear hormone receptor, NR2E3.

177 Nuclear hormone receptors (NRs) are major targets for ph

178 Certain nuclear hormone receptors (NRs) play a pivotal role in l

179 The recruitment of coactivators by nuclear hormone receptors (NRs) promotes transcription b

180 Nuclear hormone receptors (NRs) regulate physiology by s

181 d on G protein-coupled receptors (GPCRs) and nuclear hormone receptors (NRs), respectively.

182 an acetyl-CoA carboxylase (ACC) and certain nuclear hormone receptors (NRs).

183 The orphan nuclear hormone receptor, nuclear receptor subfamily 4,

184 Nuclear hormone receptors of the NR4A subgroup have been

185 Synthetic peptides that specifically bind nuclear hormone receptors offer an alternative approach

186 Pathway analyses implicated nuclear hormone receptors, particularly retinoic acid an

187 vestigated the possibility that the GATA and nuclear hormone receptor pathways are functionally linke

188 One of these pathways - that of the nuclear hormone receptor peroxisome proliferator activat

189 The nuclear hormone receptor peroxisome proliferator-activat

190 Activation of the nuclear hormone receptor peroxisome proliferator-activat

191 The nuclear hormone receptor peroxisome proliferator-activat

192 The nuclear hormone receptor peroxisome proliferator-activat

193 tion (mediated by CDK9), and activity of the nuclear hormone receptor peroxisome proliferator-activat

194 nosa (PAO1) is enhanced by activation of the nuclear hormone receptor peroxisome proliferator-activat

195 responses, we examined the expression of the nuclear hormone receptor peroxisome proliferator-activat

196 Although both inhibitors are ligands for the nuclear hormone receptor peroxisome proliferator-activat

197 We investigated whether the nuclear hormone receptor peroxisome proliferator-activat

198 -inflammatory actions both by activating the nuclear hormone receptor peroxisome proliferator-activat

199 The nuclear hormone receptor peroxisome proliferator-activat

200 The nuclear hormone receptor peroxisome proliferator-activat

201 ized low-density lipoprotein receptor-1, the nuclear hormone receptors peroxisome proliferator-activa

202 of CML through their ability to activate the nuclear hormone receptor, peroxisome proliferator activa

203 The nuclear hormone receptor, peroxisome proliferator-activa

204 sis, we demonstrate that the NGFIB family of nuclear hormone receptors plays a critical part in the r

205 thyl ascochlorin (AS-6) is an agonist of the nuclear hormone receptor PPARgamma and has been shown to

206 pase D2 (PLD2) and binds to and inhibits the nuclear hormone receptor PPARgamma with nanomolar affini

207 G-protein-coupled receptors (GPCRs) and the nuclear hormone receptor PPARgamma.

208 This nuclear hormone receptor (PPARgamma) regulates glucose h

209 hormone receptors, it enhances activation by nuclear hormone receptors presumably through its interac

210 iferator-activated receptor (PPAR)gamma is a nuclear hormone receptor primarily characterized for its

211 Conserved nuclear hormone receptors promote expression of the mlt-

212 Two new nuclear hormone receptors, PXR and SXR, have been identi

213 ism regulated by DNA demethylation-dependent nuclear hormone receptor recruitment.

214 Nuclear hormone receptors regulate diverse metabolic pat

215 RXR, a member of the superfamily of nuclear hormone receptors, regulates gene transcription

216 The difficulty in identifying ligands for nuclear hormone receptors remains an obstacle to underst

217 which encode a cytochrome P450 enzyme and a nuclear hormone receptor, respectively.

218 dden Markov model for predictive modeling of nuclear hormone receptor response elements coupled with

219 ediate transcriptional activation by RA, the nuclear hormone receptor retinoic acid receptor (RAR) an

220 of the transcriptional repressor Id2 and the nuclear hormone receptor retinoic acid-related orphan re

221 LG100268 (LG268), a synthetic ligand for the nuclear hormone receptor retinoid X receptor, on the exp

222 We screened the nuclear hormone receptor RevErbalpha (Nr1d1), a key cons

223 Their differentiation requires the nuclear hormone receptor RORgammat working with multiple

224 ptional activation cell assays and in silico nuclear hormone receptor screening revealed that certain

225 ents for a series of target families: GPCRs, nuclear hormone receptors, serine proteases, protein kin

226 The orphan nuclear hormone receptor Seven-up (Svp) is necessary and

227 on factor Wt1 to stimulate expression of the nuclear hormone receptor Sf-1 (Nr5a1) in the AGP prior t

228 4,5) triphosphate, a proposed ligand for the nuclear hormone receptor SF-1 (NR5A1).

229 ction cascades (PI3K and MAPK) converging on nuclear hormone receptors (SF-1/LRH-1) to modulate their

230 , we report that an evolutionarily conserved nuclear hormone receptor signaling pathway governs devel

231 ated intersection between these two critical nuclear hormone receptor signaling pathways provides a g

232 ide G-protein-coupled receptors (GPCRs), and nuclear hormone receptors significantly exceed limits fo

233 By screening the human nuclear hormone receptor siRNA library, we identified re

234 The orphan nuclear hormone receptor small heterodimer partner (SHP)

235 We demonstrate that the nuclear hormone receptor ssFTZ-F1 is a key modulator of

236 ortant mediators of CYP3A4 expression is the nuclear hormone receptor, steroid and xenobiotic recepto

237 The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR

238 hree members of the NR4A1/Nur77/NGFIB orphan nuclear hormone receptor subfamily (NR4A1, NR4A2, and NR

239 r coactivator-1 (SRC-1) is a coactivator for nuclear hormone receptors such as estrogen and progester

240 has been shown to act as a co-activator for nuclear hormone receptors such as estrogen receptor (ER)

241 For example, Hsp90 maintains several nuclear hormone receptors, such as the estrogen receptor

242 seven-transmembrane G-coupled receptors, and nuclear hormone receptors, suggesting that they provide

243 Members of the nuclear hormone receptor superfamily function as key tra

244 Members of the NR4A subgroup of the nuclear hormone receptor superfamily have emerged as key

245 ceptor-gamma (PPAR-gamma) is a member of the nuclear hormone receptor superfamily of ligand-activated

246 ctivated receptors (PPAR) are members of the nuclear hormone receptor superfamily of ligand-activated

247 The ER is a member of the nuclear hormone receptor superfamily of transcription fa

248 ted receptor (PPAR)-gamma is a member of the nuclear hormone receptor superfamily that can promote ce

249 farnesoid X receptor (FXR), a member of the nuclear hormone receptor superfamily, and TGR5, a G prot

250 We report here that a member of the nuclear hormone receptor superfamily, chicken ovalbumin

251 the liver X receptor (LXR), a member of the nuclear hormone receptor superfamily, inhibits inflammat

252 r the Liver X Receptor (LXR), members of the nuclear hormone receptor superfamily, prevent the develo

253 or alpha (PPARalpha) is a member of the PPAR nuclear hormone receptor superfamily, which can be activ

254 d X receptor (FXR, NR1H4) is a member of the nuclear hormone receptor superfamily, which plays an ess

255 ligand-activated transcription factor of the nuclear hormone receptor superfamily.

256 and ligand-independent NR4A subfamily of the nuclear hormone receptor superfamily.

257 erved and most ancient NR4A subfamily of the nuclear hormone receptor superfamily.

258 s a ligand-activated transcription factor of nuclear hormone receptor superfamily.

259 arnesoid X receptor (FXR) is a member of the nuclear hormone receptor superfamily.

260 ted transcription factors that belong to the nuclear hormone receptor superfamily.

261 ted receptor (PPAR) delta is a member of the nuclear hormone receptor superfamily.

262 TH receptors (TRs), which are members of the nuclear hormone receptor superfamily.

263 transcription factor that is a member of the nuclear hormone receptor superfamily.

264 en receptor (ER), an important member of the nuclear hormone receptor superfamily.

265 tivated receptors (PPARs) are members of the nuclear hormone receptor superfamily.

266 tivated receptors (PPARs) are members of the nuclear hormone receptor superfamily.

267 receptor homolog 1 (LRH-1; NR5A2), an orphan nuclear hormone receptor that controls lipid and glucose

268 Estrogen receptor alpha (ER-alpha) is a nuclear hormone receptor that controls selected genes, t

269 The vitamin D receptor (VDR) is a nuclear hormone receptor that controls transcription of

270 ator-activated receptor gamma (PPARgamma), a nuclear hormone receptor that exhibits wound-healing and

271 or-activated receptor-gamma (PPARgamma) is a nuclear hormone receptor that is critical for adipogenes

272 is elegans, uncoordinated (unc)-55 encodes a nuclear hormone receptor that is necessary for coordinat

273 soid X receptor (FXR), a bile acid-activated nuclear hormone receptor that regulates bile acid metabo

274 The vitamin D receptor (VDR) is a nuclear hormone receptor that regulates cell proliferati

275 ceptor homolog 1 (NR5A2, LRH-1) is an orphan nuclear hormone receptor that regulates diverse biologic

276 nist of the farnesoid X receptor, which is a nuclear hormone receptor that regulates glucose and lipi

277 patterning requires thyroid hormone beta2, a nuclear hormone receptor that regulates transcription in

278 Rev-erbbeta is a heme-binding nuclear hormone receptor that represses a broad spectrum

279 proliferator-activated receptors (PPARs) are nuclear hormone receptors that act as ligand-activated t

280 e proliferator-activated receptor (PPAR) are nuclear hormone receptors that are activated by endogeno

281 tivated receptors (PPARs) are a subfamily of nuclear hormone receptors that function as ligand-activa

282 d gamma (RARalpha, RARbeta and RARgamma) are nuclear hormone receptors that regulate fundamental proc

283 NCOA4 is a transcriptional coactivator of nuclear hormone receptors that undergoes gene rearrangem

284 tional expression of coactivators and of the nuclear hormone receptors themselves.

285 e following pregnancy lack the expression of nuclear hormone receptors, thereby recapitulating many c

286 nit, which is known to interact with several nuclear hormone receptors through its LXXLL motifs, pote

287 e ability to interact with and transactivate nuclear hormone receptors through its N-terminal transac

288 In this study we show that another nuclear hormone receptor, thyroid hormone receptor (TR),

289 unction in the nucleus, including the orphan nuclear hormone receptor TLX.

290 primarily through cognate sterol-responsive nuclear hormone receptors to control these processes thr

291 ific nuclear receptor (PNR/NR2E3), an orphan nuclear hormone receptor, to human breast cancer.

292 motor neurons and, together with the UNC-55 nuclear hormone receptor, to prevent aberrant VD synapti

293 alpha/PPARalpha, plus potentially additional nuclear hormone receptors, to HBV RNA synthesis and repl

294 rotein classes (G protein-coupled receptors, nuclear hormone receptors, voltage- and ligand-gated ion

295 nism of ligand dependence is not specific to nuclear hormone receptors, we anticipate that our protei

296 erythroid-derived 2, heat shock factor, and nuclear hormone receptors, which regulate stress-respons

297 ator-activated receptor gamma (PPARgamma), a nuclear hormone receptor with anti-inflammatory effects,

298 ivation of the liver X receptor, LXRalpha, a nuclear hormone receptor with known roles in hepatic lip

299 which combine the ligand-binding domains of nuclear hormone receptors with a highly sensitive thymid

300 fold selectivity versus PR and other related nuclear hormone receptors, with improved solubility as c