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1 were full length, containing the N-terminal nuclear localization signal.
2 way for mediating ligand-induced exposure of nuclear localization signal.
3 mutation is combined with the deletion of a nuclear localization signal.
4 by driving Esp1 into the nucleus with a SV40 nuclear localization signal.
5 tional changes in the STAT3 dimer masked its nuclear localization signal.
6 ed' fluorescent proteins sandwiched around a nuclear localization signal.
7 ains a nuclear export signal (NES) but not a nuclear localization signal.
8 uttling of Staufen1 into the nucleus via its nuclear localization signal.
9 -based domains, a proline-rich region, and a nuclear localization signal.
10 both the C-terminal basic stretch and basic nuclear localization signal.
11 Its N-terminus harbors a nuclear localization signal.
12 inase-2 inhibitor or by mutating a predicted nuclear localization signal.
13 ncluding a functional coiled-coil domain and nuclear localization signal.
14 rt, and serine 114, within a PKA site in the nuclear localization signal.
15 h-like nuclear export signal and an adjacent nuclear localization signal.
16 tandem zinc finger domain contains an active nuclear localization signal.
17 calize TRAF3 to the nucleus via a functional nuclear localization signal.
18 ot merely the consequence of expression of a nuclear localization signal.
19 d in the nucleus by the addition of an SV-40 nuclear localization signal.
20 rapid when the fusion includes an additional nuclear localization signal.
21 es its C-terminal transmembrane domain and a nuclear localization signal.
22 MRKTKLAPT (residues 16 to 24) that acts as a nuclear localization signal.
23 ted to nuclei after exposure of a C-terminal nuclear localization signal.
24 s induction, although AnkG lacks a predicted nuclear localization signal.
25 were achieved by selectively mutating virion nuclear localization signals.
26 y chosen nucleoplasmic sequences and 12% for nuclear localization signals.
27 ith Srp1, a nuclear import factor that binds nuclear localization signals.
28 d in the nucleus and identify two functional nuclear localization signals.
29 e the nuclear import of viral genome via its nuclear localization signals.
30 band at 95-100 kDa, which lacked N-terminal nuclear localization signals.
31 identified, including a bipartite classical nuclear localization signal, a mitochondrial matrix targ
32 c that control its localization, including a nuclear localization signal, a nuclear retention domain
34 s introduced to ablate a previously reported nuclear localization signal also resulted in a significa
35 referred to as pUL31, containing a bipartite nuclear localization signal, an intrinsically disordered
36 has four targeting sequences: two classical nuclear localization signals, an INM sorting motif, and
37 ontains 2 separable functional signatures, a nuclear localization signal and a putative EDGE motif, t
39 lude that exons 5-15 of kazrin, encoding the nuclear localization signal and C-terminal domain, are n
40 ivities of both a peptide-encoded N-terminal nuclear localization signal and C-terminal nuclear expor
41 vely spliced Set-beta transcript lacking the nuclear localization signal and demonstrated that the fu
43 The truncated Leo1(LA1186) protein lacks a nuclear localization signal and is distributed mostly in
45 al subunit (MUC1-C) is devoid of a classical nuclear localization signal and is targeted to the nucle
46 One of its isoforms, DNAJB6a, contains a nuclear localization signal and regulates beta-catenin s
47 is behavior requires coordinated action of a nuclear localization signal and reversible G protein (he
48 try to show that ICAP1 contains a functional nuclear localization signal and that nuclear localizatio
49 Both proteins contain a consensus bipartite nuclear localization signal and were found in the nucleu
50 e splicing, but specific Rbfox isoforms lack nuclear localization signals and accumulate in the cytop
51 type zinc finger domains (PS51024) and bears nuclear localization signals and highly conserved sequen
52 gle-pass transmembrane protein with multiple nuclear localization signals and no known domains or mot
53 ype of targeting motif that is distinct from nuclear localization signals and that can be computation
54 retains conserved Myc box regions but lacks nuclear localization signals and the bHLHZ domain essent
55 e N-terminally truncated PTBP3 isoforms lack nuclear localization signals and/or most of the RRM1 dom
57 The NH(2)-terminal transactivation domain, nuclear localization signal, and bHLH/LZ domain of N-Myc
58 protein sequence indicated the presence of a nuclear localization signal, and subcellular fractionati
59 at least three sites including T170 near the nuclear localization signal, and T170 was shown to deter
60 tains Golgi targeting information, a cryptic nuclear localization signal, and three caspase cleavage
61 show that NF-kappaB dimerization properties, nuclear localization signals, and binding to cytosolic I
63 t, and DNA-dependent protein kinase kinases; nuclear localization signals; and a Zn finger domain.
66 the sumoylation site at Lys(1172) or of the nuclear localization signal at Lys(1147) abolished L1-st
67 ion of R495X FUS, which abrogates a putative nuclear localization signal at the C-terminus of FUS, in
68 ion of adenovirus harboring cyclin D1 with a nuclear localization signal attenuated HF under PO in th
69 s to the N-terminal DNA-binding domains, the nuclear localization signal becomes more highly exchangi
70 , tumor-derived mutant LT (MCV350) lacking a nuclear localization signal binds hVam6p but fails to in
71 le-366-Ala-390, which includes the bipartite nuclear localization signal, binds to the p38alpha-docki
72 h a kinase substrate is fused to a bipartite nuclear localization signal (bNLS) and nuclear export si
74 a resistance is disrupted by mutation of the nuclear localization signal, but is restored upon coexpr
75 is of urothelial cell DNA is therefore not a nuclear localization signal, but its manipulation holds
76 leus, likely due to the insertion of cryptic nuclear localization signals by a frame shift caused by
78 utive import of proteins harboring a classic nuclear localization signal (cNLS) or the spontaneous nu
80 cell death with defects in M9- and classical nuclear localization signal (cNLS)-mediated protein impo
81 elated isoforms contains predicted classical nuclear localization signals (cNLS) within exons 7 and 1
84 A longer DCL4 transcript isoform encoding a nuclear localization signal, DCL4(NLS), is present in Ar
85 A, K364A, and K376A) in conjunction with the nuclear localization signal deletion did not result in c
86 rther, overexpression of TEF3-1, but not its nuclear localization signal-deletion mutant (TEF3-DeltaN
87 mouse overexpressing exogenous FUS without a nuclear localization signal (DeltaNLS-FUS), which develo
88 he RanBP9-Delta1/N60 fragment, which lacks a nuclear localization signal, displayed enhanced cytoplas
89 form of pyruvate kinase protein fused with a nuclear localization signal enhanced cell proliferation
90 ) does not localize to nuclei, as it lacks a nuclear localization signal equivalent to that present i
92 olipase A2 function for endosomal escape and nuclear localization signals for nuclear targeting and (
93 saturated, nonactivating fatty acids inhibit nuclear localization signal formation by destabilizing t
94 tein, and this localization is dictated by a nuclear localization signal found in the Adi3 T-loop ext
97 dopsis TET genes was investigated by pAtTET::NUCLEAR LOCALIZATION SIGNAL-GREEN FLUORESCENT PROTEIN/be
98 minal 25 amino acids of MxB to function as a nuclear localization signal; however, the ability of the
99 t at residues 11-27 and an isoleucine-lysine nuclear localization signal (IK-NLS) motif at residues 3
100 This difference, together with the lack of a nuclear localization signal in any of the AnkA orthologu
102 mutations have been shown to deteriorate the nuclear localization signal in FUS and thereby facilitat
104 l in the hinge domain, we identified a novel nuclear localization signal in the A/B domain of thyroid
105 a mechanism whereby L takes advantage of the nuclear localization signal in the COOH region of 2A to
106 ice expressing human TDP-43 with a defective nuclear localization signal in the forebrain (hTDP-43-De
108 on of WT GRs or those with a mutation in the nuclear localization signal in the muscle of MGRKO mice
110 asmic shuttling protein, and it contains two nuclear localization signals in the basic region and one
111 ucleocapsids, which leads to the exposure of nuclear localization signals in the C terminus of core p
113 was correlated with the retention of defined nuclear localization signals in the protein sequence, ex
114 inantly in the nucleus through the action of nuclear localization signals in the repeated regions of
115 ocalization studies identified and confirmed nuclear localization signals in XLG2 and XLG3 and a nucl
117 nus of green fluorescent protein (GFP) and a nuclear localization signal is fused to the amino termin
118 We demonstrate that the putative bipartite nuclear localization signal is not required, but the tet
119 distribution of NRDE-3 requires a functional nuclear localization signal, is required for nuclear RNA
120 shorter isoform, which lacks the N-terminal nuclear localization signal, is restricted to the cytopl
122 rt of TDP-43 protein, as a disruption of its nuclear localization signal leads to mislocalization and
123 Instead, this ability is dependent on a nuclear localization signal located in its N-terminal 40
126 ORF57 correlates with the intact N-terminal nuclear localization signal motifs of ORF57 and takes pl
127 e these sequences do not correspond to known nuclear localization signal motifs, they represent a new
128 interacted with recombinant NEMO but not the nuclear localization signal mutant version and induced n
131 nlike most substrates that carry a classical nuclear localization signal (NLS) and bind to importin a
132 tified a highly conserved putative bipartite nuclear localization signal (NLS) and demonstrated that
133 N-terminal region of FMDV 3D that acts as a nuclear localization signal (NLS) and in template bindin
134 mpelling evidence that Cby harbors bona fide nuclear localization signal (NLS) and nuclear export sig
135 A fusion protein between RecA containing a nuclear localization signal (NLS) and the DNA-binding do
138 plex, eVP24 recognizes a unique nonclassical nuclear localization signal (NLS) binding site on KPNA5
140 in-of-function genetic approach, a bipartite nuclear localization signal (NLS) derived from the nucle
141 ctional studies that UNE-S harbours a robust nuclear localization signal (NLS) directing SerRS to the
143 upstream of the helicase domain; however, no nuclear localization signal (NLS) has been identified by
144 AR protein domains, including the canonical nuclear localization signal (NLS) in the AR hinge region
145 e describe the identification of a potential nuclear localization signal (NLS) in the C-terminal regi
146 pha) can translocate proteins that contain a nuclear localization signal (NLS) into the nucleus.
150 The study documents multifunctionality of a nuclear localization signal (NLS) located at the N-termi
151 leasing importin alpha/beta from a bipartite nuclear localization signal (NLS) located in the tail do
152 uctural analysis suggests that a monopartite nuclear localization signal (NLS) may reside in the N-te
154 nteraction domain although it does possess a nuclear localization signal (NLS) motif, whilst Cry3 lac
156 ts with hBVR nuclear export signal (NES) and nuclear localization signal (NLS) mutants demonstrated i
158 e recharacterized the importin-alpha binding nuclear localization signal (NLS) of rat ChREBP, identif
160 at Ser826 and Ser828, located in a putative nuclear localization signal (NLS) on the Drosophila mela
161 s simplex virus 1 (HSV-1) mutant lacking the nuclear localization signal (NLS) on the ICP0 gene (0Del
162 Within this region, mutation of the putative nuclear localization signal (NLS) PGKMV diminished, but
163 used to probe the binding modes between the nuclear localization signal (NLS) polypeptide of NF-kapp
168 ition of the simian virus 40 large-T-antigen nuclear localization signal (NLS) results in the nuclear
171 e analyzed the structure and conservation of nuclear localization signal (NLS) sequences previously i
172 egument protein VP1-2 contains an N-terminal nuclear localization signal (NLS) that is critical for c
174 inase acting on RNA (ADAR1) carries a unique nuclear localization signal (NLS) that overlaps one of i
176 scent protein (GFP) reporter fusion assays a nuclear localization signal (NLS) that was mapped to a 2
177 protein into the hepatocyte cytoplasm and a nuclear localization signal (NLS) to enter its nucleus.
178 1 (M1) of influenza virus A/WSN/33 when its nuclear localization signal (NLS) was disrupted by R101S
180 ted mutant mouse, nBmp2NLS(tm), in which the nuclear localization signal (NLS) was inactivated to pre
181 for nuclear localization, and a nonclassical nuclear localization signal (NLS) was mapped to a short,
182 ining a cell penetrating peptide (CPP) and a nuclear localization signal (NLS) were synthesized and t
184 y, we report that Nurr1 contains a bipartite nuclear localization signal (NLS) within its DNA binding
186 he CTD of topo IIalpha, while preserving the nuclear localization signal (NLS), enhances the decatena
187 ntaining a cell penetrating peptide (CPP), a nuclear localization signal (NLS), or a bifunctional CPP
188 ents and translocated into the nucleus via a nuclear localization signal (NLS), specific among kerati
189 serine and threonine residues adjacent to a nuclear localization signal (NLS), thereby abrogating it
190 RanGTP is required in the nucleus to release nuclear localization signal (NLS)-containing cargo from
192 alpha's mediate nuclear transport by linking nuclear localization signal (NLS)-containing proteins to
193 o not support nuclear translocation of a p53 nuclear localization signal (NLS)-containing substrate p
194 plasmodesmata, targeted to the nucleus in a nuclear localization signal (NLS)-dependent manner, wher
195 pherin heterodimer alpha2beta1 in vitro in a nuclear localization signal (NLS)-dependent manner.
196 triphosphate (RanGTP) gradient that imports nuclear localization signal (NLS)-specific cargoes (NLS-
208 nit, Importin alpha (Imp alpha), and variant nuclear localization signals (NLS) representing a range
209 with (30-nm diameter) and without (< 10 nm) nuclear localization signals (NLS), macroscopic transpor
213 importin Kap95, which functions on classical nuclear-localization signal (NLS)-bearing substrates.
214 amino-terminal residues (1-45) including the nuclear localization signal (NLS1) are dispensable.
216 sine residues within the peptides containing nuclear localization signals (NLSs) 1 and 2 were non-ace
217 ycete plant pathogen Phytophthora sojae uses nuclear localization signals (NLSs) for translocation of
219 classical nucleocytoplasmic import pathway, nuclear localization signals (NLSs) in cargo proteins ar
221 use model with mutations that inactivate the nuclear localization signals (NLSs) of Apc (Apc(mNLS)).
222 destined for import into the nucleus contain nuclear localization signals (NLSs) that are recognized
223 , unlike their bacterial homologues, possess nuclear localization signals (NLSs) to enter the cell nu
224 karyotic proteins have been shown to contain nuclear localization signals (NLSs), although its biolog
229 l strains of influenza A viruses contain two nuclear localization signals (NLSs): a well-studied mono
230 h NRF-2alpha and NRF-2beta contain intrinsic nuclear localization signals (NLSs): the Ets domain with
231 specific modular signals for nuclear import (nuclear localization signals, NLSs) and export (nuclear
232 ) phosphorylation at S659, which exposed the nuclear localization signal of ACSS2 for importin alpha5
233 Five phosphorylation sites reside around the nuclear localization signal of Alp7, and the phosphodefi
234 mouse with point mutations in the canonical nuclear localization signal of CMAS, which relocated the
236 e novo predicted deleterious variants in the nuclear localization signal of Heterogeneous Nuclear Rib
237 of MxB to bind to HIV-1 capsid and (ii) the nuclear localization signal of MxB, which is important f
239 grow in glycerol medium, and removal of the nuclear localization signal of Rat1, the nuclear homolog
240 ccumulates in the nucleus with help from the nuclear localization signal of STAT3, activating a subse
241 leus in SBMA, we genetically manipulated the nuclear localization signal of the polyglutamine-expande
242 hydrophobic domain and a proximal C-terminal nuclear localization signal of VP4 were required for (i)
245 initiation sites: one (short form) with the nuclear localization signal only, exclusively localized
246 tein (FKBP12) fused to a cellular 'address' (nuclear localization signal or nuclear export sequence).
247 r demonstrated via the assembly of stable QD-nuclear localization signal peptide bioconjugates that p
248 tin-beta in its free form or in complex with nuclear localization signal peptides as the starting con
250 BPN1 but not a truncated version lacking the nuclear localization signal protects from pathogenic TDP
252 or transportin recognizes a proline-tyrosine nuclear localization signal (PY-NLS) in the N-terminal t
255 ith the ability of VP24 to interact with the nuclear localization signal receptor for PY-STAT1, karyo
256 factor Nhp6Ap enters the nucleus via a novel nuclear localization signal recognized by calcium calmod
258 the cargo proteins, including the classical nuclear localization signals, recognized by the adaptor
259 ed by the adaptor importin-alpha, and the PY nuclear localization signals, recognized by transportin-
260 s a well-characterized basic amino acid-rich nuclear localization signal region at positions 101 to 1
261 data demonstrate that the positively charged nuclear localization signal region in the tail in apo-Os
267 ed cereals showed that all of them contain a nuclear localization signal sequence flanking to the K1
269 on the T-complex that have plant-functional nuclear localization signal sequences that may recruit i
271 targeted to nuclei, through the fusion with nuclear localization signal, still exerts strong antipro
272 chloroplast targeting signal and a putative nuclear localization signal, suggesting that they are du
274 tion factor SP1, and coexpression of SP1 and nuclear localization signal-tagged HSP27 synergistically
276 and that Orc6 and Orc1 each contain a single nuclear localization signal that is essential for nuclea
277 found that residues (20)KY(21) constitute a nuclear localization signal that is not required for the
278 gly, 817-1314 possesses a conserved putative nuclear localization signal that may facilitate the nucl
279 f these elements consists of a high-affinity nuclear localization signal that mediates indirect tethe
280 nteracts with importin alpha via a classical nuclear localization signal that recruits importin alpha
282 rization and restricting access to a primary nuclear localization signal through which the apoptogeni
283 uitment by mutating Ser rich clusters of the nuclear localization signal to Ala abolished nuclear imp
284 rions parallels effects of the attachment of nuclear localization signal to Sis1, indicating that Cur
285 ic construction is also used in multipartite nuclear localization signals to provide broad substrate
286 We fuse the ADAR2 domain, tagged with a nuclear localization signal, to an RNA binding peptide f
289 e N-terminal 25 amino acids to function as a nuclear localization signal was not required for restric
290 pocotyl 1 (FHY1) and fhy1-like, an intrinsic nuclear localization signal was proposed to be involved
291 o called PAD4 or PADV), the only PADI with a nuclear localization signal, was previously shown to act
292 e PredictNLS algorithm uncovered a potential nuclear localization signal, whereas the algorithm DBS-P
293 t present in the shorter isoform, contains a nuclear localization signal, whereas the C terminus of B
296 ntry of dreCmas1 was mediated by a bipartite nuclear localization signal, which seemed irrelevant for
297 nvolves both a nuclear export sequence and a nuclear localization signal, whose activities are regula
298 a stage prior to the interaction of the Vp3 nuclear localization signal with importins, consistent w
299 the ligand-sensing beta2 loop and a tertiary nuclear localization signal within the alpha-helical cap
300 reintegration complex is further promoted by nuclear localization signals within the nucleocapsid and
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