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1 ied subnuclear fractions (e.g., nucleoli and nuclear matrix).
2 Ralpha immobilization and degradation to the nuclear matrix.
3 all amount of both proteins localized to the nuclear matrix.
4 in or LexA relocalized these proteins to the nuclear matrix.
5 RNA splicing and attachment of dsRNA to the nuclear matrix.
6 soluble nuclear substructures, including the nuclear matrix.
7 soluble nuclear fraction, referred to as the nuclear matrix.
8 on the CD4 silencer via association with the nuclear matrix.
9 hat the PROP1 protein is associated with the nuclear matrix.
10 at least one of the HS appears bound to the nuclear matrix.
11 attachment of the inserted sequences to the nuclear matrix.
12 ng within the nucleus and for binding to the nuclear matrix.
13 ible roles in the organization of DNA on the nuclear matrix.
14 ts of the gypsy insulator are present in the nuclear matrix.
15 in the interaction of the telomeres with the nuclear matrix.
16 proposed to be a component of an underlying nuclear matrix.
17 creased association of the receptor with the nuclear matrix.
18 ar network of nonhistone proteins called the nuclear matrix.
19 obility of Ku70-GFP and its association with nuclear matrix.
20 e have shown that p53 can associate with the nuclear matrix.
21 ion experiments suggest that this represents nuclear matrix.
22 s on either side predicted to associate with nuclear matrix.
23 enhancer regions into close proximity at the nuclear matrix.
24 e nucleus and association of the GR with the nuclear matrix.
25 to 98) appeared important for binding to the nuclear matrix.
26 that is known to occur predominantly at the nuclear matrix.
27 t of cohesin was found to associate with the nuclear matrix.
28 occurs on a nuclear sub-structure termed the nuclear matrix.
29 gest a role for FA proteins in chromatin and nuclear matrix.
30 lls and found to localize exclusively to the nuclear matrix.
31 the lack of FA proteins in chromatin or the nuclear matrix.
32 ructurally and functionally organized by the nuclear matrix.
33 untingtin fragments, which tightly bound the nuclear matrix.
34 ARs), domains that organize DNA loops on the nuclear matrix.
35 ) was originally isolated from avian oviduct nuclear matrix.
36 n redistribution between the nucleoplasm and nuclear matrix.
37 ecyl sulfate-soluble and associated with the nuclear matrix.
38 at Lhx3 is found in both the nucleoplasm and nuclear matrix.
39 Hic-5 in Cos-1 cells was associated with the nuclear matrix.
40 TA binding protein from association with the nuclear matrix.
41 C domain, independently associated with the nuclear matrix.
42 phorylated and specifically localized to the nuclear matrix.
43 spermatids and associated with chromatin and nuclear matrix.
44 ), sites necessary for DNA attachment to the nuclear matrix.
45 dition to being an integral component of the nuclear matrix.
46 n, both being localized primarily within the nuclear matrix.
47 as important for PDLIM2 to interact with the nuclear matrix.
48 mmobile FGFR1 population associated with the nuclear matrix.
49 tained by interaction with the RNA-dependent nuclear matrix.
50 s but not proteins bound to chromatin or the nuclear matrix.
51 n isoform associated with PML bodies and the nuclear matrix.
52 r components such as the nuclear envelope or nuclear matrix.
53 XL9 was also found to be associated with the nuclear matrix.
54 of estrogen receptor-alpha (ERalpha) in the nuclear matrix accompanied by rapid degradation by the u
55 tem cells and is dependent on the C-terminal nuclear matrix anchor domain of CIZ1 and the E repeats o
57 ch likely pulls the HIV DNA segment into the nuclear matrix and away from transcriptional machinery,
58 on reveals that the FA proteins are found in nuclear matrix and chromatin and that treatment with mit
62 lay neurons marked during development by the nuclear matrix and DNA binding factor Satb2 (ISR(Satb2))
63 ar substrates that includes both DNA and the nuclear matrix and may represent a mechanism for repair
66 raction of cyclin D3 was associated with the nuclear matrix and repression of >200 genes including th
68 that Sp2 preferentially associates with the nuclear matrix and speculate that this subcellular local
70 key nuclear structures (e.g., chromatin and nuclear matrix), and enables its recombinational repair
71 y within subnuclear foci associated with the nuclear matrix, and 2) these foci are distinct from prom
74 hermore, menin is localized to chromatin and nuclear matrix, and the association with nuclear matrix
75 stem to study how transcription factors, the nuclear matrix, and the cytoskeleton interact to control
76 subnuclear domains, including chromatin, the nuclear matrix, and the nuclear envelope, where sphingol
77 n co-localized with endogenous AKAP95 in the nuclear matrix, and the physical interaction between fid
78 nx complexes are associated in situ with the nuclear matrix, and this association requires the intran
80 romere protein F (CENPF), a component of the nuclear matrix, are severely reduced at kinetochores in
82 othelial cells, cyclin E is recruited to the nuclear matrix as cells differentiate and this can be ma
85 poptosis) demonstrated dynamic modulation of nuclear matrix-associated B23 without a significant chan
86 in CEM cells preferentially localize to the nuclear matrix-associated DNA indicating their in vivo M
88 hereas the U(L)31 gene product of HSV-1 is a nuclear matrix-associated phosphoprotein previously show
89 drawing the receptor into close proximity to nuclear matrix-associated proteasomes that facilitate ER
90 leophosmin/numatrin (B23) is a key nucleolar/nuclear matrix-associated protein required for cell grow
91 olocalized and coimmunoprecipitated with the nuclear matrix-associated protein Runx2 in osteoblasts.
99 hese results provide the first evidence that nuclear matrix association dynamically mediates the loop
100 nd overhangs at the telomeres and an altered nuclear matrix association of telomeres in these cells.
101 ts are likely to be mediated by the enhanced nuclear matrix association of the ubiquitylation-resista
102 For IgH transactivation, Bright binds to nuclear matrix association regions upstream of certain v
103 t zinc-"finger" that is sufficient to direct nuclear matrix association, and this region also encodes
105 ount of initial template associated with the nuclear matrix at 15 unique regions spanning the beta-gl
108 pUC18 and pUC18 plasmids containing various nuclear matrix attachment region (MAR) sequences suggest
109 ond, structural boundary is represented by a nuclear matrix attachment region (MAR), situated about 3
111 ese results suggest that NPM associates with nuclear matrix attachment region DNA in heat-shocked cel
113 lating the human CD8 gene complex, we mapped nuclear matrix attachment regions (MARs) and DNase I hyp
114 ce with different configurations of flanking nuclear matrix attachment regions (MARs) encompassing th
115 as identified as a protein that bound to the nuclear matrix attachment regions (MARs) of the immunogl
117 ls lie near cellular sequences identified as nuclear matrix attachment regions (MARs), while integrat
119 that this domain exhibits characteristics of nuclear matrix attachment regions (MARs): an exceptional
123 otein, two methods were employed to localize nuclear matrix attachment sites within intron 1 of the h
126 otein belongs to the same family as SATB1, a nuclear matrix-attachment region binding protein implica
127 ndings suggest that BLM is part of a dynamic nuclear matrix-based complex that requires PML and funct
128 ation, HP1, and SATB1, topoisomerase engages nuclear matrix binding as minor marks of histone acetyla
129 etween the highly conserved PIASy N-terminal nuclear matrix binding domain (SAPD) and the C/EBPdelta
130 also found that TCF-4, beta-catenin, and the nuclear matrix binding protein SMAR1 tether at the -143-
132 experiments suggested that BLM resides in a nuclear matrix-bound complex in which association with h
133 y function in the nucleus in the assembly of nuclear matrix-bound protein complexes involved with tra
134 high molecular weight DNA fragments from the nuclear matrix by promoting topoisomerase II-catalyzed D
135 volved in the attachment of chromatin to the nuclear matrix, chromatin remodeling and transcription r
136 istant to salt extraction and behaves like a nuclear matrix/chromosome scaffold-associated structure.
137 he ATPase activity, HELLS is retained at the nuclear matrix compartment, defined in part by lamin B1.
140 ded here demonstrate that examination of the nuclear matrix composition allows differentiation of col
141 ar protein in carrot (Daucus carota), called Nuclear Matrix Constituent Protein1 (NMCP1), which conta
142 hat attachment of genes to the NaCl-isolated nuclear matrix correlates with their silencing in HeLa c
143 rescence microscopy, MINT adopts a reticular nuclear matrix distribution that overlaps transcriptiona
145 gesting that the observed high CKB levels in nuclear matrix extracts are caused by the enhanced local
146 ents of CGBP that fail to associate with the nuclear matrix fail to localize to nuclear speckles and
147 helix crippled PDLIM2 in shutting Tax to the nuclear matrix for ubiquitination-mediated degradation,
148 nsformed cells, PDLIM2 shuttles Tax into the nuclear matrix for ubiquitination-mediated proteasomal d
156 oplasmic/nucleoplasmic, chromatin-bound, and nuclear matrix fractions) showed increased hyperphosphor
161 ing evidence for this functional role of the nuclear matrix has been elusive and has recently been fu
162 that the dynamic interaction of p53 with the nuclear matrix has to be considered for a full understan
164 sitively with the level of expression of the nuclear matrix high mobility group (HMG) proteins HMGI(Y
165 Pem introns and pre-mRNA accumulated in the nuclear matrix, high salt-soluble, and DNase-sensitive f
166 iated gene activation shifted FGFR1 from the nuclear matrix (immobile) to chromatin (slow) and reduce
167 end of the 20th century, the concept of the nuclear matrix implies the existence of a nuclear skelet
168 nt promoter in vitro and associates with the nuclear matrix in a DNA-independent fashion, 3) zebrafis
169 for the first time, that p53 is bound to the nuclear matrix in primary cultures of normal mammalian c
171 the insulator tethers the SP-10 gene to the nuclear matrix in somatic tissues, sequestering the core
173 hat cyclin E, but not A, is mounted upon the nuclear matrix in sub-nuclear foci in differentiated ver
174 ysis of the results obtained in the study of nuclear matrix in the light of current views on the orga
175 of the polycomb complex and the role of the nuclear matrix in the process of X chromosome inactivati
176 have identified p53 in association with the nuclear matrix in viral- and non-viral transformed cell
180 hey also mediate binding of chromatin to the nuclear matrix in vivo and alter the topology of the gen
181 distinguish between a network-like 'internal nuclear matrix' (INM) and a 'nuclear shell' that connect
185 of a well defined locus control region, the nuclear matrix is considered the primary candidate regul
187 ts of p53 revealed that association with the nuclear matrix is independent of the tertiary and quater
192 progesterone-regulated avian c-myc gene, and nuclear matrix-like attachment sites flank the RBF eleme
193 ike the fibrogranular structures termed the "nuclear matrix." Like the residual material seen in nucl
195 bility that the residual material termed the nuclear matrix may be enriched in, if not formed by, den
196 nuclear entry, association of Lhx3 with the nuclear matrix may contribute to LIM homeodomain factor
197 mans, dynamic alterations in the chromosomal nuclear matrix may modulate the -sigma of certain DNA re
199 evated in rapidly proliferating tissues, and nuclear matrix (NM) is an important subnuclear locale of
200 eous Nuclear Ribonucleoprotein U (HNRNPU), a nuclear matrix (NM)-associated protein, in 3D genome org
201 teraction of the Ifng gene promoter with the nuclear matrix occurred differentially in a lineage-spec
202 ermatocyte stage with the recruitment to the nuclear matrix of a large approximately 9.6-kb region ju
204 is present within nuclei and can target the nuclear matrix of CV-1 cells, cultured prostate cancer c
205 high molecular weight DNA fragments from the nuclear matrix of HL-60 leukemia cells, which preceded t
206 The helicase and AKAP95 co-localized in the nuclear matrix of mammalian cells, associated in vitro,
209 fically increases mRNA and protein levels of nuclear matrix peptides lamins A and C, suggesting that
211 ile atrophin-1 and ETO/MTG8 cofractionate in nuclear matrix preparations from brains of DRPLA transge
212 matrix." Like the residual material seen in nuclear matrix preparations, the hnRNP filaments were in
216 ermediary factor 1 gamma, anti-MDA5 and anti-nuclear matrix protein 2, which are potentially exploita
218 rug Administration (FDA) approved the use of Nuclear matrix protein 22 (NMP22) as a monitoring tool f
220 (such as ribosomal proteins L3, L5, and L28; nuclear matrix protein 84; matrin cyclophilin; the H3 hi
224 This work identifies phosphorylation of the nuclear matrix protein matrin 3 as a new conserved targe
225 rupts the 3' UTR of MATR3, which encodes the nuclear matrix protein Matrin 3, and mouse Matr3 is stro
226 member of the BTB/Kelch repeat family, is a nuclear matrix protein normally expressed in neurons but
227 ived 2 (E2)-related factor 2 (NRF2) with the nuclear matrix protein NRP/B was essential for the trans
228 in breast cancer cells, we observed that the nuclear matrix protein NRP/B was expressed and colocaliz
230 ting with both the nuclear envelope and DNA, nuclear matrix protein NuMA (Nuclear mitotic apparatus),
231 elopmental Cell, Agrelo et al. show that the nuclear matrix protein SATB1 is a critical determinant o
232 l, Grosschedl and colleagues report that the nuclear matrix protein Satb2 represses Hoxa2 expression
233 Scaffold attachment factor-B1 (SAFB1) is a nuclear matrix protein that has been proposed to couple
234 t in part through the inhibition of SATB2, a nuclear matrix protein that is a critical determinant of
235 he Nrf2 pathway, identifying a novel role of nuclear matrix protein(s) in oxidative stress responses.
236 locytic leukemia zinc finger, nucleophosmin, nuclear matrix protein, and signal transducer and activa
240 hypothesis that fulvestrant induces specific nuclear matrix protein-ERalpha interactions that mediate
242 ral scaffolding of the nucleus, and specific nuclear matrix proteins (NMPs) have been identified as a
243 ine novel protein-protein interactions among nuclear matrix proteins and suggest a potential role of
245 quence specifically interacted with isolated nuclear matrix proteins in vitro, suggesting that it may
247 binding to WW domain or SMAD proteins or the nuclear matrix retain this growth regulatory ability.
248 equences that independently target SRm160 to nuclear matrix sites at splicing speckled domains: amino
250 se proteins were coimmunoprecipitated from a nuclear matrix-solubilized fraction, and the purified re
251 ed for interaction with focal adhesions, the nuclear matrix, steroid receptors, and the tau2 domain o
253 of RAI1 was found in the chromatin bound and nuclear matrix subcellular fractions while the mutant pr
255 had a greatly diminished localization to the nuclear matrix, suggesting the presence of a nuclear mat
262 ermore, the HTY mutation overlaps the unique nuclear matrix targeting signal of Runx factors and exhi
264 n of physiological signals, and contains the nuclear matrix targeting signal, the protein motif that
265 conservation of the nuclear localization and nuclear matrix targeting signals suggests that the LIM h
270 the glucocorticoid receptor that includes a nuclear matrix-targeting signal and the tau2 transcripti
272 have identified point mutations of the Runx2 nuclear matrix-targeting signal sequence that impair its
277 RNA- and DNA-binding protein enriched in the nuclear matrix that also plays a role in the regulation
278 teraction of the Ifng gene promoter with the nuclear matrix that may set off transcription in activat
279 isrupts the association between hbrm and the nuclear matrix; the 160-kDa hbrm cleavage fragment is le
280 ctures are thought to be associated with the nuclear matrix, they appear to be released from this mat
282 Splice variants of the Nmp4 gene include nuclear matrix transcription factors that regulate the t
284 reased targeting of androgen receptor to the nuclear matrix upon overexpression of paxillin may be br
286 n monocytes, can tether the TNF locus to the nuclear matrix via matrix attachment region formation, p
290 Strong association of the promoter with the nuclear matrix was observed only in the Th1 cell subset
291 ell fraction that would today be termed "the nuclear matrix" was first described and patented in 1948
292 n of TPZ is/are thought to be at or near the nuclear matrix, we hypothesized that TPZ may have a majo
293 in was previously shown to reside within the nuclear matrix, we show here that a significant amount o
294 uited Tax from its functional sites into the nuclear matrix where the polyubiquitinated Tax was degra
295 -dependent binding of the XPA protein to the nuclear matrix, which was also observed in UV light-trea
296 ed here is to anchor hyperedited RNAs to the nuclear matrix, while allowing selectively edited mRNAs
297 8 with atrophin-1 recruits atrophin-1 to the nuclear matrix, while atrophin-1 and ETO/MTG8 cofraction
299 icited proteasomal degradation of Tax in the nuclear matrix with concomitant inhibition of NF-kappaB
300 terized by heterogeneous condensation of the nuclear matrix without formation of discrete chromatin m
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