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1 on to the previously identified sites (i.e., nuclear membranes).
2 dditional ESCRT-III proteins to holes in the nuclear membrane.
3 amina and particle budding through the inner nuclear membrane.
4 sprin-1 and KLC-1/2 interaction at the outer nuclear membrane.
5 nd delivered by membrane fusion at the outer nuclear membrane.
6 mediate lamin filaments that lines the inner nuclear membrane.
7 C) and are required for budding at the inner nuclear membrane.
8 ant form of lamin A (termed progerin) to the nuclear membrane.
9 erstanding how capsids bud through the inner nuclear membrane.
10 cell or in trafficking of the capsid to the nuclear membrane.
11 of emerin, an integral protein of the inner nuclear membrane.
12 t grow radially from rafted receptors to the nuclear membrane.
13 ructure and function, primarily at the inner nuclear membrane.
14 an interaction between OGT and PIP(3) at the nuclear membrane.
15 wth, SPB duplication, or distribution in the nuclear membrane.
16 1-UNC-84-domain protein that spans the inner nuclear membrane.
17 elope by fusing with and budding through the nuclear membrane.
18 7 expression results in reduplication of the nuclear membrane.
19 hesion and for chromosome recruitment to the nuclear membrane.
20 fferences in binding affinities in the inner nuclear membrane.
21 ane (INM) and deenveloping them at the outer nuclear membrane.
22 on interactions between chromosomes and the nuclear membrane.
23 rnalized through vesicular structures to the nuclear membrane.
24 ids exit the nucleus by budding at the inner nuclear membrane.
25 (NE) at fusion sites of the inner and outer nuclear membrane.
26 membrane but instead was associated with the nuclear membrane.
27 organized in a punctate pattern on the inner nuclear membrane.
28 d consist of chromatin surrounded by its own nuclear membrane.
29 nuclear migration and localizes to the outer nuclear membrane.
30 6-10 foci that dynamically interact with the nuclear membrane.
31 k lining the nucleoplasmic side of the inner nuclear membrane.
32 erevisiae to the INM as opposed to the outer nuclear membrane.
33 d an SRD-YFP fusion localize with AAL to the nuclear membrane.
34 came a muscle-specific resident of the inner nuclear membrane.
35 d depth until they fused with the flat outer nuclear membrane.
36 eading to its rapid degradation at the inner nuclear membrane.
37 at links repressive chromatin with the inner nuclear membrane.
38 the association of pSmad3 with Imp8 and the nuclear membrane.
39 a cells indicate that SINC targets the inner nuclear membrane.
40 inuclear space surrounded by inner and outer nuclear membranes.
41 evenly spaced bilayers, the inner and outer nuclear membranes.
42 cilitated by microtubules, which pull on the nuclear membranes.
43 h the formation of the NEC and remodeling of nuclear membranes.
44 that diffusion barriers compartmentalize the nuclear membranes.
45 he endoplasmic reticulum and move within the nuclear membranes.
46 lined channel connecting the inner and outer nuclear membranes.
47 s unclear how this complex is able to engage nuclear membranes.
48 narrower spaces between the inner and outer nuclear membranes, (3) reduced numbers of nuclear pores
49 (but not other torsin family members) causes nuclear membrane abnormalities in Tor1a(DeltaE/DeltaE) n
52 imaged single nuclear pore complexes in the nuclear membrane and aggregates of GFP-conjugated Tau pr
53 critical for processing lamin A on the inner nuclear membrane and clearing clogged translocons on the
54 p63alpha were localized to the cytoplasm and nuclear membrane and co-immunoprecipitated in the same f
56 zed to hydrophobic perinuclear features, the nuclear membrane and inside the nucleus within minutes.
58 , Kuduk (Kud), which can reside at the outer nuclear membrane and is required for the development of
59 However, when active transport is across the nuclear membrane and NF-kappaB is additionally actively
60 eases in O(2)(-) (3.5-fold; P<0.01) from the nuclear membrane and nuclear exit of HDAC4 in cardiomyoc
61 or envelopment of nucleocapsids at the inner nuclear membrane and optimal viral DNA synthesis and DNA
62 mooth distribution of pU(L)34/pU(L)31 at the nuclear membrane and precluded the accumulation of virio
63 omplex (NEC), which is anchored to the inner nuclear membrane and provides a scaffold for the assembl
64 or protein expression forms a complex at the nuclear membrane and remodels these membranes to generat
65 mplex consists of KASH proteins in the outer nuclear membrane and SUN proteins in the inner nuclear m
67 ibility that protein regulation at the inner nuclear membrane and the nuclear lamina contributes to t
68 e-controlled breakdown and reassembly of the nuclear membrane and the restoration of transcription af
69 cells, TLE1 and NOD2 co-localized around the nuclear membrane and TLE1 inhibited activation of nuclea
70 -type virus recruits protein kinase C to the nuclear membrane and triggers its activation, whereas th
72 lthough NOX4 protein immunolocalized to both nuclear membranes and intranuclear inclusions, fluoresce
75 ristic accumulation of capsids away from the nuclear membrane, and an overall defect in nuclear impor
76 l regulators to ensure that mitotic spindle, nuclear membrane, and nuclear pore assembly occur exclus
78 ades identify interactions at the tonoplast, nuclear membrane, and pollen tube plasma membrane, empha
79 , traffic from the location of fusion to the nuclear membrane, and undergo the process of uncoating,
80 ted cellular fractions, including cytosolic, nuclear, membrane, and mitochondrial protein extracts.
82 Lipid microdomains localized in the inner nuclear membrane are considered platforms for active chr
84 ges in the separation of the inner and outer nuclear membrane are responsible for the additional fluc
86 emonstrate for the first time that the inner nuclear membrane Asi proteins function in a degradation
90 [4, 5] that requires A-type lamin, an inner nuclear membrane-associated protein, to accelerated agin
91 ivity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formati
92 s dependent on the surface area of the outer nuclear membrane available to interact with aster microt
98 oreover, with the divergence of preocclusion nuclear membrane breakdown in betabaculoviruses and memb
99 l contact with genomic DNA from the time the nuclear membrane breaks down in prometaphase until early
101 nuclear lamina, nuclear pore complexes, and nuclear membrane, but it is distinct from nuclear envelo
102 f TAG storage capacity, Pah1 still binds the nuclear membrane, but lipid precursors are redirected to
103 that hindered diffusion of cPKA through the nuclear membrane by a rapid-binding process, but not glo
105 69 in the nucleus and can be tethered to the nuclear membrane by virtue of its interaction with the w
107 alteration of lamin localization pattern and nuclear membrane change are further supported by in vivo
108 dence that nuclear pore complexes (NPCs) and nuclear membranes coevolved with the endomembrane system
109 ps3 mutants was exacerbated, suggesting that nuclear membrane composition affects spindle pole body f
110 d of proteins within the inner and the outer nuclear membranes, connects the nuclear lamina to the cy
111 ; 2) intracellular mechanics of cellular and nuclear membranes, contractile actin stress fibers, and
113 ng intralumenal vesicles fuse with the outer nuclear membrane, delivering the capsids to the cytoplas
115 are expressed together, numerous virion-size nuclear membrane-derived vesicles were evident at the nu
118 sphorylations required for the initiation of nuclear membrane disassembly during mitosis are adapted
121 itro resembles capsid budding into the inner nuclear membrane during HSV-1 infection and nuclear enve
123 thought to receive arachidonic acid from the nuclear membrane-embedded 5-LOX-activating protein (FLAP
124 telomere tethering and gene silencing at the nuclear membrane, establishment of sister chromatid cohe
125 at generation and maintenance of NP requires nuclear membrane expansion, actin, and the exocyst compl
127 cell diameter, low cell stiffness, and high nuclear membrane fluctuations are highly clonogenic and
130 egress, herpesvirus capsids bud at the inner nuclear membrane forming perinuclear viral particles tha
131 promotes chromosome coalescence, preventing nuclear membranes from enwrapping individual chromosomes
132 These results map the crucial inner/outer nuclear membrane fusion event of NPC assembly downstream
134 teracts directly with Kar5p, suggesting that nuclear membrane fusion is mediated by a protein complex
137 protein, Prm3p, was found to be required for nuclear membrane fusion; disruption of PRM3 caused a str
138 ecture and vital biological functions of the nuclear membranes, how they achieve and maintain such a
139 I components to a virus egress domain on the nuclear membrane.IMPORTANCE The ESCRT system is hijacked
141 topic membrane protein residing in the inner nuclear membrane in association with the nuclear lamina.
142 antibody gave very specific labeling of the nuclear membrane in healthy neurons, with apparent reloc
143 rved that NOX4 and p22(phox) localize to the nuclear membrane in MV4-11 cells expressing FLT3-ITD.
145 s by budding through the inner and the outer nuclear membranes in a nuclear egress mechanism akin to
146 ed to reside in the endoplasmic reticulum or nuclear membrane) in lysates of infected cells and with
147 a smaller amount of CA than complexes at the nuclear membrane, in the cytoplasm, or in controls.
148 e 1 UL34 that localize properly to the inner nuclear membrane, indicating interaction with UL31, but
149 mitoylation of Rif1 anchored it to the inner nuclear membrane, influencing its role in heterochromati
150 amily of transmembrane proteins of the inner nuclear membrane (INM) [8, 9], to form the so-called LIN
151 veloping DNA-containing capsids at the inner nuclear membrane (INM) and deenveloping them at the oute
152 ly sites at a time that coincides with inner nuclear membrane (INM) and outer nuclear membrane (ONM)
153 ion to uncover new constituents of the inner nuclear membrane (INM) by comparative BioID analysis of
154 membrane proteins are targeted to the inner nuclear membrane (INM) by diffusion within the membrane
155 virus 1 nucleocapsids bud through the inner nuclear membrane (INM) into the perinuclear space to obt
156 tanding the protein composition of the inner nuclear membrane (INM) is fundamental to elucidating its
159 Sad1/UNC-84 (SUN)-domain proteins are inner nuclear membrane (INM) proteins that are part of bridgin
160 y, such as the conserved SUN family of inner nuclear membrane (INM) proteins, is necessary to elucida
161 that EGFR is then translocated to the inner nuclear membrane (INM) through the INTERNET (integral tr
162 cell surface EGFR is trafficked to the inner nuclear membrane (INM) through the nuclear pore complexe
163 ptor 5 (mGluR5) is concentrated at the inner nuclear membrane (INM) where it mediates Ca(2+) changes
164 Cargo is recruited, enveloped at the inner nuclear membrane (INM), and delivered by membrane fusion
165 eus undergo primary envelopment at the inner nuclear membrane (INM), and then enveloped virus particl
166 otein 1 (SUN1), which localizes to the inner nuclear membrane (INM), are part of the linker of nucleo
167 s were dome-shaped evaginations of the inner nuclear membrane (INM), that grew in diameter and depth
168 ately 100 proteins are targeted to the inner nuclear membrane (INM), where they regulate chromatin an
175 evidence that nesprin-2G localization to the nuclear membrane is altered under high-force conditions.
176 lamina is specifically rearranged, the outer nuclear membrane is altered, and the nucleus becomes per
177 iffusion, the probability of AR crossing the nuclear membrane is an important factor in determining t
178 We also see that human torsinA at the inner nuclear membrane is associated with membrane expansion a
181 dition, the tethering of the inner and outer nuclear membranes is lost during infection due to a decr
183 (LINC) complex, composed of outer and inner nuclear membrane Klarsicht, ANC-1, and Syne homology (KA
184 results indicate that VP4 forms pores in the nuclear membrane leading to lysis and virus release.
185 nd revealed only partial colocalization with nuclear membrane markers, probably due to post-mortem ti
186 rafficking of envelope proteins to the inner nuclear membrane, mediated partly through the FP25K prot
188 accumulate aberrantly in herniations of the nuclear membrane, much as in cells infected with a U(S)3
189 n of CCTalpha is needed for expansion of the nuclear membrane network, but mechanisms for CCTalpha nu
197 ay occur when active transport is across the nuclear membrane only, or when no species are subject to
199 d1/UNC-84 (SUN) proteins interact with outer nuclear membrane (ONM) Klarsicht/ANC-1/Syne homology (KA
200 nificantly reduced at both the INM and outer nuclear membrane (ONM) of cells infected with a U(L)34 n
201 ng loss, encodes nesprin-4 (NESP4), an outer nuclear membrane (ONM) protein expressed in the hair cel
202 amma-tubulin, depends on Nesprin-1, an outer nuclear membrane (ONM) protein that connects the nucleus
203 eticulum and then transported from the outer nuclear membrane (ONM) to the inner nuclear membrane (IN
205 the spindle pole body for insertion into the nuclear membrane or affect spindle pole body duplication
206 earing nucleic acid, derived from either the nuclear membrane or the closely associated rough endopla
207 intracellular particles associated with the nuclear membrane or the nucleus compared to that for con
208 ents interact with many partners such as the nuclear membrane, other chromosomes or nuclear bodies, b
210 els in the same excised cytoplasmic-side-out nuclear membrane patches exposed alternately to optimal
211 tides in the eukaryotic cell nucleoplasm and nuclear membrane prompted us to study the putative inter
212 In this issue, Ohsaki et al. show that the nuclear membrane, promyelocytic leukemia bodies, and the
217 ly functional lysine-less mutant of an inner nuclear membrane protein in yeast, Asi2, is polyubiquity
218 n, nuclear fragmentation and cleavage of the nuclear membrane protein lamin A, expression of pro-apop
219 s) torsinA (TA) and its activator, the inner nuclear membrane protein lamina-associated polypeptide 1
220 t BMAL1 is positively modulated by the inner nuclear membrane protein MAN1, which directly binds the
223 Strikingly, we also find that the inner nuclear membrane protein Sun1 antagonizes Sun2 LINC comp
224 9 mice that are also deficient for the inner nuclear membrane protein Sun1 show markedly reduced tiss
225 d that LINC complexes that contain the inner nuclear membrane protein Sun2 promote focal adhesion ass
226 ines, prompting us to test whether emerin, a nuclear membrane protein that interacts with lamins and
229 megalovirus (HCMV), this complex consists of nuclear membrane protein UL50, and nucleoplasmic protein
230 ncoding the lamin B receptor (LBR), an inner nuclear membrane protein whose expression is required fo
232 Lamin B receptor (LBR) is a bifunctional nuclear membrane protein with N-terminal lamin B and chr
233 Lamin B receptor (LBR), an integral inner nuclear membrane protein, also contains a functional C14
234 is physically associated with another inner nuclear membrane protein, Nur1, and deletion of either l
236 icates that, like plasma membrane integrins, nuclear membrane proteins assemble into actin-dependent
237 arrays of outer (nesprin2G) and inner (SUN2) nuclear membrane proteins assembled on and moved with re
240 f the LEM (Lap2-Emerin-Man1) family of inner nuclear membrane proteins, and the ESCRT-II/ESCRT-III hy
243 ligomerization of the luminal domains of two nuclear membrane proteins, nesprin-2 and SUN2, which int
244 SUN-1 are hypothesized to be outer and inner nuclear membrane proteins, respectively, and to interact
245 (Lap2-emerin-MAN1) family of integral inner nuclear membrane proteins, which binds to an early NPC a
251 ticles that subsequently fuse with the outer nuclear membrane, releasing capsids into the cytoplasm.
252 irions that subsequently fuse with the outer nuclear membrane, releasing capsids into the cytosol.
254 with translocation from the cytoplasm to the nuclear membrane, resulting in increased membrane phosph
255 ve that untethering chromatin from the inner nuclear membrane results in highly deformable nuclei in
256 ALA + DFO showed hepatocyte autophagosomes, nuclear membrane ruffling, and porphyrin-containing vacu
257 e nucleus, causing chromatin protrusions and nuclear membrane ruptures at sites with nuclear lamina d
259 ice (Tor1a(DeltaE/DeltaE)) exhibit disrupted nuclear membranes selectively in neurons, mimicking the
260 isolated nucleoplasts stripped of the outer nuclear membrane showed progressive nuclear localization
261 ects, a previously identified determinant of nuclear membrane stability, but did decrease the number
262 generates diacylglycerol from PA, targets a nuclear membrane subdomain that is in contact with growi
263 s (emerin, MAN1, LAP1, and LBR) of the inner nuclear membrane, suggesting that SINC interacts with ho
265 , we find that isolated nuclei lacking inner nuclear membrane tethers are less stiff than wild-type n
266 observed significantly more distant from the nuclear membrane than its nontranslocated counterpart, w
268 rm complexes with KASH proteins of the outer nuclear membrane that connect the nuclear envelope (NE)
270 ammalian dynein-binding protein of the outer nuclear membrane that forms a meiotic complex with Sun1.
271 1 (LAP1) is an integral protein of the inner nuclear membrane that has been implicated in striated mu
273 s complex mediates capsid transit across the nuclear membrane, the regulatory components are not clea
274 romatin without prominent margination at the nuclear membrane; they exhibited small punctate nucleoli
275 smic protein UL53, which is recruited to the nuclear membrane through its interaction with UL50.
276 UNC-84 recruits KASH proteins to the outer nuclear membrane to bridge the nuclear envelope (NE), me
278 ape whereby nascent capsids bud at the inner nuclear membrane to form perinuclear virions that subseq
281 ndent and AA-independent steps that occur on nuclear membranes to control the assembly of the LT synt
282 ric structure that fuses the inner and outer nuclear membranes to form a central channel of ~60 nm in
285 red for HSV capsids to bud through the inner nuclear membrane, to the vertex-specific complex of HSV
287 ns of RNAs into discrete foci at or near the nuclear membrane triggered by multiple elements; and a n
288 sed of BFRF1 and BFLF2 was visualized at the nuclear membrane using autofluorescent protein fusions.
289 aracterizing calcium release channels in the nuclear membrane, very little is known regarding the pro
290 y biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding.
292 7 cells, we could image invaginations of the nuclear membrane, vimentin fibrils, the mitochondrial ne
293 lamin B2 (LB2), normally associated with the nuclear membrane, was identified as an unexpected major
294 s KASH protein UNC-83 localizes to the outer nuclear membrane where it recruits kinesin-1 to provide
296 ar, of which approximately 60% is located on nuclear membranes, where activation leads to sustained C
297 5-lipoxygenase (5-LO) enzyme translocates to nuclear membranes, where it associates with its scaffold
298 ge proteinaceous channels embedded in double nuclear membranes, which carry out nucleocytoplasmic exc
299 uclear envelope thought to connect the inner nuclear membrane with the underlying nuclear lamina and
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