ライフサイエンスコーパス: nucleation

1 sition state of the rate-determining step of nucleation.

2 terpret as the onset of homogeneous etch pit nucleation.

3 ine clusters is connected to the kinetics of nucleation.

4 activate gamma-TuRC to promote branching MT nucleation.

5 gy affects the critical size for dislocation nucleation.

6 eeds through impurity-mediated heterogeneous nucleation.

7 he earliest stages of AP2 activation and CCP nucleation.

8 = 0.0024) corresponding reduction in bubble nucleation.

9 with divergent functions beyond microtubule nucleation.

10 e large Gibbs energy barrier associated with nucleation.

11 ials are exceptionally effective at inducing nucleation.

12 ubulin superfamily essential for microtubule nucleation.

13 ough a pathway dominated by surface-enhanced nucleation.

14 f CsgA by circumventing the lag phase during nucleation.

15 tubule (MT) and promote actin polymerization nucleation.

16 tivate N-WASP-WIP- and Arp2/3-mediated actin nucleation.

17 s critical for MT binding and facilitates MT nucleation.

18 cids play a key role in atmospheric particle nucleation.

19 investigate the role of TPX2 in branching MT nucleation.

20 sition and realizing spatial control over Li nucleation.

21 uman FHOD1 both accelerate actin assembly by nucleation.

22 ffects both primary nucleation and secondary nucleation.

23 ould therefore be an example of nonclassical nucleation.

24 ing molecules, including gamma-TuRC-mediated nucleation activator (gamma-TuNA) domain-containing prot

25 contained within newly identified gamma-TuRC nucleation activator motifs.

26 The nucleation activity of FHOD1 is restricted to cytoplasmi

27 lity, metabolic activity, viability, and ice-nucleation activity of investigated bacteria.

28 Most of the nucleation activity of Lmods resides within a fragment e

29 g through recruitment of Akap450-mediated MT nucleation activity to the NE.

30 n an approximately threefold decrease in the nucleation activity, which is only partially accounted f

31 , cultivability, metabolic activity, and ice-nucleation activity.

32 ng medium [3-6], which appear to provide the nucleation, alteration, elongation, and inhibition mecha

33 mechanistic target of rapamycin C2 (mTORC2) nucleation and activity leading to tumor growth and incr

34 The competition between nucleation and annihilation produces a very complex depe

35 d be broadly useful for studying microtubule nucleation and assembly pathways of other polymers.

36 rt the role of EVs as early sites of mineral nucleation and demonstrate their value for promoting har

37 Because uniform Li nucleation and deposition can be fulfilled owing to the

38 rthermore, experiments can hardly detect the nucleation and early stages of growth because of the sho

39 een previously shown to decrease its rate of nucleation and elongation into amyloid-like fibrils link

40 n that uses as a read-out the changes in the nucleation and elongation rate constants caused by candi

41 The primary nucleation and elongation rates strongly decreased with

42 The strength of nucleation and elongation varies widely across formins.

43 f each acyl group on the rate of SOD1 fibril nucleation and elongation were quantified in vitro with

44 nse of metals is the ability to model defect nucleation and evolution mechanisms during plastic defor

45 the free and upper troposphere, promote ice nucleation and facilitate long-range transport of reacti

46 and PI3KC3-C1 complexes might coordinate the nucleation and fusion of Atg9 and COPII vesicles at the

47 t depth triggered rapid heterogeneous bubble nucleation and growth and could have enhanced eruption e

48 rmal treatment), and thoroughly exploits the nucleation and growth as well as subsequent superlattice

49 arameters not only provide insights into the nucleation and growth as well as transformation of vario

50 The difference in MOF nucleation and growth kinetics of the two solutions was

51 rve discrete nucleation events and sigmoidal nucleation and growth kinetics.

52 tuned the parameters to a growth mode where nucleation and growth occur upon heating and ahead of th

53 with slow kinetics largely restricted by the nucleation and growth of a new phase.

54 vestigate the effect of this additive on the nucleation and growth of apatite crystals.

55 re, we report unexpected observations on the nucleation and growth of intragranular cracks in a comme

56 ugh alumina dielectric leads to bias-induced nucleation and growth of silver nanoparticles in the ITO

57 er continued UV irradiation both resulted in nucleation and growth of SOA particles.

58 The nucleation and growth of solids from solutions impacts m

59 irm the NC concentration/solubility mediated nucleation and growth of superlattice, in which an evapo

60 The reaction proceeds through nucleation and growth of the new phase in corners of the

61 t precursor solutions to obtain a sequential nucleation and growth phase.

62 , providing direct evidence for a concurrent nucleation and growth process instead of a shrinking-cor

63 Little is known about their nucleation and growth processes, which involve a combina

64 Pb(Br0.2 I0.8 )3 precursor solution and the nucleation and growth stages of the thin film formation

65 d according to classical concepts of crystal nucleation and growth, and that long-standing physical c

66 ing, the formation of nucleation precursors, nucleation and growth, and the relaxation of the system,

67 cytoskeletal remodeling by controlling actin nucleation and microtubule (MT) stabilization to facilit

68 ticle aging time course is characteristic of nucleation and particle growth; rates for these processe

69 d 2 (FH1-FH2) domains of DAAM catalyze actin nucleation and processively mediate filament elongation.

70 ith the disintegration of grains rather than nucleation and propagation from visible boundaries betwe

71 gnitudes reflect differences in the rates of nucleation and propagation of dislocations within the cr

72 and provide important insights regarding the nucleation and propagation of single-cell patterns.

73 ly is subject to different forces regulating nucleation and propagation steps and provide evidence th

74 This study focused on ice nucleation and propagation, related water shifts and xyl

75 Contributions from misoriented surface nucleation and rotational intergrowths are eliminated.

76 myloFit show that NUCB1 affects both primary nucleation and secondary nucleation.

77 ously unknown many-body mechanisms of vortex nucleation and show that angular momentum is hidden in p

78 tarity is a critical determinant for amyloid nucleation and structural selection.

79 rmational changes activate AP2 to drive both nucleation and subsequent stabilization of nascent CCPs.

80 d cooling of milk enhances the mechanisms of nucleation and that extended storage induces lipid reorg

81 le grounds for the study of directed crystal nucleation and the controlled growth of soft matter.

82 d protrusion (via activation of Arp2/3 actin nucleation) and Rho-mediated contraction (via ROCK phosp

83 tested: bimolecular nucleation, termolecular nucleation, and a mechanism termed "alternative termolec

84 lipid vesicles, which are known to stimulate nucleation, and find that this compound displaces alpha-

85 most reasonable more intimate mechanisms of nucleation are tested: bimolecular nucleation, termolecu

86 Following nucleation as many microgranules throughout the nucleoid

87 d can be explained by more spatially regular nucleation as the QD density increases.

88 on of the mature QDs relaxing by dislocation nucleation at a later stage in the growth, independently

89 ause arsenic acts as an inhibitor for pyrite nucleation at ambient temperature.

90 A activity, which facilitates clustered GDMT nucleation at distinct Golgi sites.

91 The work demonstrates that seeding induces nucleation at low temperatures accelerating the crystall

92 the phospholipid PI(3)P and promoting actin nucleation at nascent autophagosomes.

93 Noncentrosomal microtubule (MT) nucleation at the Golgi generates MT network asymmetry i

94 ubcomplex of Atg1 is critical for phagophore nucleation at the PAS.

95 e for the direction-randomizing influence of nucleation away from centrosomes.

96 isfit (0.03 +/- 0.04 per cent) decreases the nucleation barrier for precipitation, thus enabling and

97 mental studies identifying that S lowers the nucleation barrier of the catalyst nanoparticles.

98 er, are more likely to grow and overcome the nucleation barrier.

99 lymer interactions, thereby lowering polymer nucleation barrier.

100 ffective not only in eliminating homogeneous nucleation but also in activating and sustaining the gro

101 /w) of PGEmix-8 did not significantly affect nucleation but slightly retarded crystal growth.

102 ficantly changed the rate of alpha-synuclein nucleation, but did not markedly affect the rate of fibr

103 resence of free hRPA inhibits RAD51 filament nucleation, but has a lesser impact upon filament elonga

104 synergized with Coronin in inhibiting actin nucleation by Arp2/3 complex.

105 egrees wedge is found to greatly enhance ice nucleation by facilitating the formation of special topo

106 T behavior of NbO2 follows the field-induced nucleation by investigating the delay time dependency at

107 ential role in microtubule (MT)-dependent MT nucleation by recruiting the gamma-tubulin complex to MT

108 models have been proposed for actin filament nucleation by the bacterial proteins VopL/F.

109 and that long-standing physical concepts of nucleation can describe multistep, multiphase growth mec

110 s shows that significant enhancements of ice nucleation can emerge both when the geometry of a wedge

111 ity faster than its surrounding can act as a nucleation center for reentry and can anchor an induced

112 on took several hours and occurred in apical nucleation centers, either close to or in association wi

113 ry generically exists on the surfaces of ice nucleation centres, its role in nucleation remains poorl

114 in components myosin 1b, actin and the actin nucleation complex Arp2/3.

115 with ARX-2, a component of the Arp2/3 actin-nucleation complex.

116 LASPs resulted in drastically decreased GDMT nucleation, computational modeling revealed that only ga

117 The nucleation-condensation mechanism represents a major par

118 This nucleation confers a silenced state that is metastably i

119 wo-stage kinetic model using principles from nucleation-controlled protein polymerizations; the key d

120 extremely thin precursor layer, reduces the nucleation density dramatically under a thermodynamicall

121 a reveal that at neutral pH NFGAIL follows a nucleation dependent mechanism to form amyloid fibrils.

122 ation have come to the fore, suggesting that nucleation-dependent aggregation may occur in a localize

123 e residues, htt(e1) starts to aggregate in a nucleation-dependent manner.

124 Aggregation is a nucleation-dependent process in which the pre-nucleation

125 Zonda nucleation depends on Atg1, Atg13, and Atg17 but does no

126 plastic deformation mechanisms (dislocation nucleation, dissociation/recombination behavior, disloca

127 onductance variations can be modelled by the nucleation-dominated reversal of domains.

128 rmal fluctuations enable rate-dependent pore nucleation, driving the dynamics of the swell-burst cycl

129 eed, originating from the stochastic crystal nucleation during the crystallization of amorphous germa

130 e thought to be responsible for the high ice nucleation efficacy of potassium (K)-feldspar particles.

131 amyloidogenic regions as a potential site of nucleation enabling dimerisation and subsequent fibril f

132 The decrease in the nucleation energy barrier is calculated, exhibiting its

133 conditions in the xylem should favor bubble nucleation even more: there are millions of conduits wit

134 ntration inside pores, which enables crystal nucleation even under conditions where heterogeneous nuc

135 Fibril formation involves a spontaneous nucleation event in which soluble alpha-syn monomers ass

136 c dimeric viral RNA-Gag interactions are the nucleation event of infectious virion assembly, ensuring

137 formation mechanism, and we observe discrete nucleation events and sigmoidal nucleation and growth ki

138 ucleation-dependent process in which the pre-nucleation events are dominated by Abeta homotypic inter

139 The real-time visualization of stochastic nucleation events at electrode surfaces is one of the mo

140 suggests that EGCG interferes with secondary nucleation events known to generate toxic Abeta assembli

141 To the best of our knowledge, stochastic nucleation events of nanoscale copper deposits are visua

142 ogen and sulphur tracers link these frequent nucleation events to biogenic precursors released by ope

143 ning endosomes by interacting with the actin-nucleation factor FHOD4, which slowed the trafficking of

144 e closely linked WHAMM gene, which encodes a nucleation factor.

145 Actin nucleation factors function to organize, shape, and move

146 lude that VopL/F function primarily as actin nucleation factors that remain briefly ( approximately 1

147 It is found that the nucleation, formation, and morphological properties of c

148 tion scheme results in lower homogeneous ice nucleation frequency than previously reported, and a dec

149 this approach, it is possible to change tin nucleation from a stochastic to a deterministic process,

150 nnihilation of interstitials at jogs and jog nucleation from clusters are diffusion-controlled and ca

151 It has been shown that nucleation from methanesulfonic acid (MSA) and amines, w

152 However, a function for MT nucleation from the NE in nuclear positioning has not be

153 ystems, we provide evidence for a role of MT nucleation from the NE on nuclear spreading in myotubes.

154 her centrosomal proteins, is required for MT nucleation from the NE.

155 imately 85% of VopL/F molecules also promote nucleation from the pointed end, whereas a smaller fract

156 he activity of topographical features in the nucleation from vapor of ice and various organic crystal

157 tomic-scale mechanisms associated with their nucleation, glide, climb, and annihilation at elevated t

158 sualize the irreversible transient states of nucleation, growth, and solidification of the complex.

159 s to at least three: (i) promoting dendritic nucleation; (ii) linking actin networks to membranes; an

160 Although spin-orbit torques led to domain nucleation in continuous films and to stochastic nucleat

161 an in situ atomic-scale observation of twin nucleation in nanocrystalline Pt.

162 ety of multiphase processes ranging from ice nucleation in the atmosphere to hydration of biomolecule

163 es at or near interfaces, because homogenous nucleation in the bulk can only be observed at deep supe

164 al occurrence of NPF events likely caused by nucleation in the polar marine boundary layer was quanti

165 nanoparticle formation system revealed that nucleation in this system is an apparent second-order in

166 a mechanism termed "alternative termolecular nucleation" in which 2(COD)Ir(+) and 1(COD)Ir.POM(8-) yi

167 Arp2/3 complex, they each induced an "open" nucleation-inactive conformation.

168 tive method to form crystals is to introduce nucleation-inducing heterologous materials into the crys

169 Br) removal mechanism, changing from classic nucleation into gaseous bubbles to a facilitated removal

170 2 to gamma-TuRC intact, whereas branching MT nucleation is abolished, suggesting that TPX2 may activa

171 tracking the early stages of metallic phase nucleation is challenging.

172 ty necessary for TPX2 to induce branching MT nucleation is contained within newly identified gamma-Tu

173 These results show that bubble nucleation is dominated by DO concentration (affected by

174 an electrostatic contribution, but assembly nucleation is dominated by the recognition of the folded

175 In the "heterogeneous Golgi" model, MT nucleation is dramatically up-regulated at discrete and

176 ogy, and many industrial applications, CaCO3 nucleation is still a topic of intense discussion, with

177 Heterogeneous crystal nucleation is ubiquitous in nature and at the heart of m

178 secondary precipitation in brine begins via nucleation kinetics, and this could not be described wit

179 ose two plausible mechanistic models of GDMT nucleation leading to this phenotype.

180 lization, the relevant length scales are the nucleation length set by the nucleus size and density, a

181 uclei in small MG nanorods that approach the nucleation length, thus coined the term, nucleus starvat

182 Quantification of the nucleation locations and anisotropic growth kinetics of

183 is scaffolding protein assembles microtubule nucleation machinery is unclear.

184 d definitively rule out a simple bimolecular nucleation mechanism and provide evidence for the altern

185 large macromolecular units by a homogeneous nucleation mechanism can be quite slow and require speci

186 We find that a spontaneous actin filament nucleation mechanism is required for adequate forces to

187 This suggests that an intrinsic B-phase nucleation mechanism operates under confinement.

188 pathways include the so-called nonclassical nucleation mechanism via the assembly of thermodynamical

189 All higher molecularity nucleation mechanisms were also ruled out.

190 often used as a model system to investigate nucleation mechanisms.

191 is is likely because a significant amount of nucleation mode volatile particles were formed when the

192 mulation of these proteins follows a seeding-nucleation model, where a misfolded aggregate or 'seed'

193 f conversion reactivity allows the extent of nucleation ([nanocrystal] = 4.6-56.7 muM) and the size f

194 y, SCL's activities are all mediated through nucleation of a core quaternary protein complex (SCL:E-p

195 twist or bend, strain must accumulate until nucleation of a grain boundary is favorable compared to

196 alpha-synuclein catalyses the heterogeneous nucleation of Abeta42 aggregates.

197 ot a result of volatilization and subsequent nucleation of ABS or direct release of ABS aerosols.

198 o solute-rich and solute-poor liquid phases, nucleation of amorphous nanoclusters within the metal-ri

199 Here, the nucleation of BPs is controlled with precision by relyin

200 r l- or d-proline, which was chosen to favor nucleation of canonical beta-turn secondary structures.

201 Therefore, homogeneous and heterogeneous nucleation of CaP occurs near and at the cathode surface

202 5 crystals reveals a competition between the nucleation of Cu6Sn5 in the liquid versus growth of Cu6S

203 oplasmic organizing centres for assembly and nucleation of deuterosomes.

204 ule refolding experiments reveal the initial nucleation of folding while simulations corroborate thes

205 We also find that IFT20 regulates the nucleation of Golgi-derived microtubules by affecting th

206 Nucleation of hinge helices creates TS, burying sidechai

207 Heterogeneous nucleation of ice induced by organic materials is of fun

208 ctured that these fluctuations assist in the nucleation of ice.

209 s with long-range ordering through selective nucleation of nanocomposites on termination patterned su

210 ul for other applications that deal with the nucleation of nanoparticles under reactive conditions.

211 nown about the physical phenomena leading to nucleation of new perfect crystals within deformed metal

212 d, vinculin-linked scaffold that facilitates nucleation of phosphatidylinositol (3,4,5)-triphosphate

213 this alignment arises from the preferential nucleation of prismatic crystal planes of ice on high-en

214 of the effectiveness of porous materials for nucleation of protein crystals, and will be useful for o

215 perimental measurements that relate directly nucleation of recrystallization to the local deformation

216 in nanocrystalline metals, that promote the nucleation of separated but closely spaced partial dislo

217 eation in continuous films and to stochastic nucleation of skyrmions in magnetic tracks, no practical

218 ransition from AF to FM regions proceeds via nucleation of small vortex structures, which then grow b

219 Nucleation of the electrogenerated insoluble clusters di

220 n folds along a pathway originating from the nucleation of the N-terminal domain, and that this pathw

221 The oxidation occurs via the nucleation of the oxide phase (Cu2O) from one area of th

222 MR results are consistent with heterogeneous nucleation of the solid mineral phase driven by coral ac

223 ient of NC concentration causes simultaneous nucleation of the two superlattices.

224 ing are controlled with great precision, the nucleation of tin in solder joints is currently left to

225 examination of measurements of heterogeneous nucleation of water vapor on silver nanoparticles is pre

226 on even under conditions where heterogeneous nucleation on flat surfaces is absent.

227 e system can take in the process of skyrmion nucleation or destruction and identify that the transiti

228 podial actin networks, but the regulation of nucleation or elongation of Arp2/3-independent filament

229 ransitions between crystals follow diffusive nucleation, or various diffusionless transitions, but th

230 By analyzing the nucleation pathway, we conclude that freezing in the fil

231 ent with the idea that the K(+) channels are nucleation points for SNARE complex assembly.

232 er, modeling the integrated processes of HbS nucleation, polymerization, HbS fiber interaction, and s

233 A theory that links the nucleation potential of the surface to heat transfer rat

234 g the melting and freezing, the formation of nucleation precursors, nucleation and growth, and the re

235 erature-pressure window in which homogeneous nucleation prevents the investigation of water in its me

236 ster formation directly from measurements of nucleation probability.

237 Ice nucleation proceeds in a comparable manner, although our

238 losives that regards their condensation as a nucleation process and takes into account absolute entro

239 lar, the simulations successfully captured a nucleation process followed by a subsequent growth proce

240 t selectively the fibril-catalyzed secondary nucleation process in Abeta42 aggregation.

241 subsequently exported from the cell where a nucleation process leads to the formation of extracellul

242 The nucleation process yielding Ir(0) approximately 300 nano

243 specifically the fibril-dependent secondary nucleation process.

244 s at the micrometer length scale affect this nucleation process.

245 d protein 2/3 (Arp2/3) complex activation by nucleation promoting factors (NPFs) such as WASP, plays

246 The nucleation promoting factors Wsp1p (WASp) and Myo1p (myo

247 lymerization at obstacles coated with actin "nucleation promoting factors" (NPFs).

248 ctional cortacin (pcortactin Y421), an actin nucleation-promoting factor that has a crucial role in c

249 nd Cep170 both interact with the microtubule nucleation-promoting region of AKAP350A, whereas Cep68 i

250 ecular models of water, and observe that the nucleation rate in the film increases by seven orders of

251 eases in v-SNARE copy numbers did not affect nucleation rate.

252 Nucleation rates (lag time) also correlated with bead ma

253 lite when interpreting and extrapolating ice nucleation rates from experimental laboratory conditions

254 han hexagonal crystallites, making their ice nucleation rates more than three orders of magnitude hig

255 e forecasts hinge on good predictions of ice nucleation rates.

256 faces of ice nucleation centres, its role in nucleation remains poorly understood.

257 Dynamic flux and stochasticity during pre-nucleation renders the reactions susceptible to perturba

258 Pore nucleation required a minimum of two v-SNAREs per NLP fa

259 In the early stages, we show that nucleation requires a structural reorganization of the l

260 Pore nucleation requires zippering between vesicle-associated

261 g the boiling surface properties such as its nucleation site density, wettability, wickability and he

262 eptides on the engineered MBD1 function as a nucleation site for AuNP synthesis, allowing the constru

263 ability of all NMR parameters: Starting as a nucleation site for monomer-monomer contacts, this six-r

264 sponds to the suggested, but yet unobserved, nucleation site of L-ferritin.

265 d p.(Arg2308_Met2309dup), all falling in the nucleation site of the alpha/beta spectrin heterodimer r

266 g that the gelatinized starch could act as a nucleation site to speed crystallization.

267 y acute features provide extremely effective nucleation sites and allows us to determine the mechanis

268 lic surface property and excessive nanoscale nucleation sites created by the nanoporous surface.

269 Al/B4C interfaces provide more heterogeneous nucleation sites for the eta' precipitates in the MPZ.

270 These colloids appear to provide nucleation sites for the perovskite crystallization, whi

271 so observed for two-component systems, where nucleation sites have greater Au content than the other

272 cellular metabolism), rather than potential nucleation sites provided by cell-surfaces.

273 he silicone matrix immobilizes the epitaxial nucleation sites through self-templated cavities, which

274 rees C or colder) to induce freezing without nucleation sites, making FTVs impractical due to instrum

275 nk dislocation loops serving as the apparent nucleation sites.

276 xplain the extent to which DDX1 promotes the nucleation step of Rev-RRE assembly.

277 h the RRE RNA to specifically accelerate the nucleation step of the Rev-RRE assembly process.

278 Our ab initio calculations on gold nucleation suggest that these steps might be associated

279 anisms of nucleation are tested: bimolecular nucleation, termolecular nucleation, and a mechanism ter

280 yloid proteins through primary and secondary nucleation, the common evolution from disordered monomer

281 Most nucleation theories used to describe amyloid aggregation

282 ical capillarity for intrusion and classical nucleation theory (CNT) for extrusion-because of the pec

283 8-), not the higher order implied by classic nucleation theory and its nA right harpoon over left har

284 As a consequence, heterogeneous classical nucleation theory cannot describe our simulation results

285 We conclude that classical nucleation theory needs to be corrected to include the d

286 We use classical nucleation theory to show that the freezing efficiencies

287 are based on extrapolations using classical nucleation theory, which assumes that the structure of n

288 narios challenge central tenets of classical nucleation theory.

289 magnitude higher than predicted by classical nucleation theory.

290 F polymerizations by controlling the rate of nucleation, thereby increasing their materials quality.

291 tion stems from the reduced stochasticity of nucleation through geometrically matched and robust scan

292 mal degradation and uncontrolled homogeneous nucleation, thus enabling highly robust block-by-block e

293 us challenges of compromised MT-dependent MT nucleation to complete mitosis and cytokinesis.

294 al TPX2 version that stimulates branching MT nucleation, which we find is unrelated to TPX2's ability

295 ives are controlled thermodynamically by the nucleation, while kinetically by the enhanced Zn adsorpt

296 ediating actin polymerization through Arp2/3 nucleation, Wiskott-Aldrich syndrome protein (WASP) and

297 islocations markedly transform the diffusive nucleation with an intermediate-stage liquid into a mart

298 sharp, concave wedge can further promote ice nucleation with special wedge geometries.

299 h site is found to be rate-limiting for kink nucleation, with this process having a lower activation

300 aHP," that exhibits greatly improved amyloid nucleation without measurably enhancing beta-structure i