ライフサイエンスコーパス: nucleic acid structure

1 chromicity of the oligonucleotide or complex nucleic acid structure.

2 This too can be enhanced by nucleic acid structure.

3 key factor in the energetics that determines nucleic acid structure.

4 termination of this particularly significant nucleic acid structure.

5 een used for many years to investigate local nucleic acid structure.

6 far in the context of a chemical etiology of nucleic acid structure.

7 erentially insert adjacent to triple-helical nucleic acid structures.

8 SCHNAaP, for the analysis of double-helical nucleic acid structures.

9 l information concerning the perturbation of nucleic acid structures.

10 the hydrating water molecules in protein and nucleic acid structures.

11 ing well reflects the hierarchical nature of nucleic acid structures.

12 motor domain are amplified and redirected by nucleic acid structures.

13 nding sites, aside from those sequestered by nucleic acid structures.

14 s a mechanism to prevent recognition of self nucleic acid structures.

15 DNA repair and transcription process complex nucleic acid structures.

16 of F(Py)...H-C(Pu) pseudo hydrogen bonds in nucleic acid structures.

17 n of transcription, we have investigated two nucleic acid structures.

18 re frequently occurring structural motifs in nucleic acid structures.

19 erized as selective ligands for higher-order nucleic acid structures.

20 ionalities and enable the formation of novel nucleic acid structures.

21 ractions and potentially for designing novel nucleic acid structures.

22 olypurine tract and other A-tract-containing nucleic acid structures.

23 ction and visualization of three-dimensional nucleic acid structures.

24 yze, rebuild and visualize three-dimensional nucleic-acid structures.

25 obtain the footprint of bound proteins onto nucleic acids structures.

26 G-Quadruplexes, noncanonical nucleic acid structures, act as silencers in the promote

27 ates are used as research tools for studying nucleic acid structure and binding interactions.

28 otonation can play an important role in both nucleic acid structure and catalysis.

29 Nucleic acid structure and dynamics are known to be clos

30 powerful means of obtaining high-resolution nucleic acid structure and dynamics information that fav

31 ctional spectroscopic probe for the study of nucleic acid structure and dynamics using electron param

32 We study protein and nucleic acid structure and dynamics using single-molecul

33 ine and adenosine and has been used to probe nucleic acid structure and dynamics.

34 e role of oxygen and unsaturated moieties in nucleic acid structure and emphasizes greater use of thi

35 lies EDD has promise for characterization of nucleic acid structure and folding.

36 ive incorporation of 2'-5' linkages, whereby nucleic acid structure and function may be probed throug

37 A, it should prove very useful in studies of nucleic acid structure and function.

38 is pushing back the supposed limitations of nucleic acid structure and function.

39 agents and as analogues for the analysis of nucleic acid structure and function.

40 onic strengths, tracing these differences to nucleic acid structure and ion type.

41 ly from higher eukaryotes in many aspects of nucleic acid structure and metabolism.

42 ds and are valuable reagents in the study of nucleic acid structure and protein-nucleic acid interact

43 nderscore the sensitivity of CT chemistry to nucleic acid structure and structural dynamics.

44 Nucleobase modifications dramatically alter nucleic acid structure and thermodynamics.

45 egulation, including recruitment to specific nucleic acid structures and association with protein act

46 suggesting possible applications in probing nucleic acid structures and biochemical mechanisms.

47 ude a ligand in the input structure, process nucleic acid structures and generate a solvent box with

48 or the PDB, has also been enhanced to handle nucleic acid structures and multi-chain complexes.

49 to be a single access point for protein and nucleic acid structures and related information.

50 predict experimental observations for other nucleic acid structures and salt conditions, demonstrati

51 tituted aromatic diamidine compounds with 13 nucleic acid structures and sequences.

52 tal providing access to information about 3D nucleic acid structures and their complexes.

53 eractions, molecular dynamics simulations of nucleic acid structure, and two databases of super-enhan

54 tions from experimentally determined protein-nucleic acid structures, and provides users with a graph

55 these findings on the use of pdC to examine nucleic acid structure are discussed.

56 Photolabile nucleotides that disrupt nucleic acid structure are useful mechanistic probes and

57 Four-stranded G-quadruplex nucleic acid structures are of great interest as their h

58 ons, which are characteristic of base paired nucleic acid structures, are abolished when the covalent

59 at sensitivity of Fe.bleomycin to changes in nucleic acid structure argues that those species which d

60 e identified a significant distortion in the nucleic acid structure at the HIV-1 PPT/U3 junction in t

61 es activation upon association with specific nucleic acid structures at DNA replication forks.

62 Telomeres are the protein-nucleic acid structures at the ends of eukaryote chromos

63 tention has been given to the development of nucleic acid structures based on non-natural DNA polymer

64 robably was not an effect due to the altered nucleic acid structure, but was more likely a general ef

65 ch analysis can be extended to non-canonical nucleic acid structures, but this approach has not been

66 ndent route for determining carbohydrate and nucleic acid structure by NMR spectroscopy.

67 d interactions and ligand-induced changes in nucleic acid structure by separately resolving the intri

68 s the types of base pairs that are formed in nucleic acid structures by various combinations of the t

69 are able to adopt noncanonical four-stranded nucleic acid structures called G-quadruplexes (G4s).

70 Four-stranded nucleic acid structures called G-quadruplexes have been

71 stabilization of secondary and higher-order nucleic acid structure can be more fully understood once

72 l aptamer, which represents a highly compact nucleic acid structure, contains a wealth of new conform

73 a liver-targeting delivery system, tripodal nucleic acid structure demonstrated enhanced fluorescent

74 w insights into the molecular recognition of nucleic acid structures emerged from these studies, addi

75 earest neighbor model representation and (v) nucleic acid structure flexibility.

76 gathered suggesting that these non-canonical nucleic acid structures form in vivo and play essential

77 d transcription and to elucidation of unique nucleic acid structures formed at this origin.

78 plex DNA (G4-DNA), a family of non-canonical nucleic acid structures formed by certain G-rich sequenc

79 R-loops are three-stranded nucleic acid structures formed upon annealing of an RNA

80 Prediction of nucleic acid structure from sequence requires thermodyna

81 gram, SCHNArP, for rebuilding double-helical nucleic acid structures from a set of helical parameters

82 ing applications aimed at the elucidation of nucleic acid structure-function relationships.

83 nucleic acid labelling, the stabilization of nucleic acid structures, functionalization of nucleic ac

84 ealing refinement can have a major impact on nucleic acid structures generated from NMR data.

85 Studies of nucleic acid structure have shown little differences in

86 Sugar puckering of nucleosides impacts nucleic acid structures; hence their biological function

87 has far-reaching biological implications for nucleic acid structure in a partially solvated cellular

88 of this additional information: for example, nucleic acid structures in non-canonical conformations a

89 he small angle neutron scattering profile of nucleic acid structures in solution.

90 Tests on all nucleic acid structures in the Protein Data Bank confirm

91 , high-affinity probes of the role of bulged nucleic acid structures in various biological processes.

92 se transcription, most likely in maintaining nucleic-acid structure in the complex.

93 RING-MaP single-molecule nucleic acid structure interrogation enables concise and

94 A fundamental motif in canonical nucleic acid structure is the base pair.

95 table in vivo formation of these alternative nucleic acid structures is likely to be highly dependent

96 versity, suggesting how compact or elongated nucleic acid structures may be constructed using differe

97 ne the impact of CH...O bonds on protein and nucleic acid structure, molecular recognition, and enzym

98 een used widely to probe helical geometry in nucleic acid structures, nucleic acid-drug complexes, an

99 The nucleic acid structure of these genes was then compared

100 and label G-quadruplexes: these higher-order nucleic acid structures originate in the assembly of fou

101 e Accord" on definitions and nomenclature of nucleic acid structure parameters.

102 in the number of large, 3D, high-resolution nucleic acid structures, particularly of the 30S and 50S

103 have evolved mechanisms of evasion, masking nucleic acid structures recognized by the host, sequeste

104 ectural role in the stabilization of protein-nucleic acid structures required for strand synapsis.

105 reatment results in severe distortion of the nucleic acid structure, restriction of all hydroxyl dihe

106 Nucleic acid structure, stability, and reactivity are go

107 G-quadruplexes are nucleic acids structures stabilized by physiological con

108 ique, publication-quality representations of nucleic-acid structures, such as 'block' images of bases

109 sitivity towards very local perturbations in nucleic acid structure suggests that 2'-amine acylation

110 ic mechanisms for forming knots and links in nucleic acid structures suggests that molecules involvin

111 G-quadruplex (GQ) is a noncanonical nucleic acid structure that is formed by guanine rich se

112 G-quadruplex (G4) is a higher-order nucleic acid structure that is formed by guanine-rich se

113 G-quadruplexes are higher-order nucleic acid structures that can form in G-rich telomere

114 R loops are three-stranded nucleic acid structures that comprise nascent RNA hybrid

115 s showed that the cleavage sites were stable nucleic acid structures that contained specific arrangem

116 kew favors R-loops, a type of three stranded nucleic acid structures that form upon annealing of an R

117 ch these enzymes couple the rearrangement of nucleic acid structures to the binding and hydrolysis of

118 To understand the effect of C on nucleic acid structure, we undertook a detailed crystall

119 he competition dialysis method, 13 different nucleic acid structures were dialyzed against a common l

120 The G-quadruplex (G4) is a non-canonical nucleic acid structure which regulates important cellula

121 e for characterizing transient low-populated nucleic acid structures, which we predict will be abunda

122 (CT) properties are compared between peptide nucleic acid structures with an aminoethylglycine backbo

123 DNA:RNA hybrids, nucleic acid structures with diverse physiological funct