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1 , and lipids in the molecular composition of nucleoli.
2 ing occur in regions of the nucleus known as nucleoli.
3 ion coupled with exercise also display small nucleoli.
4 mordia, and its protein was localized to the nucleoli.
5 eudosubstrate that directly recruits Fbw7 to nucleoli.
6 y to pericentric heterochromatin-surrounding nucleoli.
7 istributed throughout nuclei and enriched in nucleoli.
8 in large nuclear aggregates that often ring nucleoli.
9 sors, and fibrillarin does not accumulate in nucleoli.
10 bserved accumulation of SUMO proteins within nucleoli.
11 e only phosphorylation site, retains FEN1 in nucleoli.
12 es in late mitosis before the reformation of nucleoli.
13 Pes1 was typically restricted to nuclei and nucleoli.
14 o a lesser extent PP1beta concentrate in the nucleoli.
15 endogenous proteins appear within mammalian nucleoli.
16 ther lack an organized nucleolus or have two nucleoli.
17 yield mature H/ACA RNPs in Cajal bodies and nucleoli.
18 s but also necessary for localizing ADAR2 to nucleoli.
19 also observed miR-206 to be concentrated in nucleoli.
20 calization of the marker protein, coilin, to nucleoli.
21 id not localize bulk sumoylated molecules to nucleoli.
22 asmic locations, Lsm proteins are present in nucleoli.
23 ver, La lacking the SBM does not localize to nucleoli.
24 ha-actinin and exhibited a nucleus with many nucleoli.
25 n the cytosol and in other cells also in the nucleoli.
26 RNp and p97/VCP physically interacted in the nucleoli.
27 t IFI16 was localized in the nucleoplasm and nucleoli.
28 pair in human cells colocalize with Mus81 in nucleoli.
29 lization of RGS6 proteins from such sites to nucleoli.
30 nuclear protein, with super accumulation in nucleoli.
31 d increased intense speckled staining in the nucleoli.
32 he U6 base-pairing region still localizes to nucleoli.
33 import of chimeric proteins into nuclei and nucleoli.
34 Drosophila variants colocalize to HeLa cell nucleoli.
35 e analysis revealed that it was localized to nucleoli.
36 s of the nucleus and was also present in the nucleoli.
37 , promyelocytic leukemia protein bodies, and nucleoli.
38 nucleolar R-loops recruited RNase H1 to the nucleoli.
39 vitro and for localization within mammalian nucleoli.
40 ssociation of Pol III-transcribed genes with nucleoli.
41 ~60% of which were detected in the H1 mutant nucleoli.
42 in vitro exhibit smaller and more elongated nucleoli.
43 distribution of MageB2 protein includes the nucleoli.
44 reduces alpha-satellite DNA association with nucleoli.
45 sed in mammalian cells, these variants bound nucleoli.
46 lear membrane; they exhibited small punctate nucleoli.
47 pheries of both replication compartments and nucleoli.
48 ting its translocation from nucleoplasm into nucleoli.
49 of MDM2 and translocation of DeltaNp63 into nucleoli.
50 ould not confirm localization of midnolin in nucleoli.
51 meric clusters, chromosomal territory 3, and nucleoli.
52 d in specific, robust accumulation of Gag in nucleoli.
54 alized to distinct nuclear bodies, including nucleoli (148), promyelocytic leukemia nuclear bodies (3
55 h a single nucleolus and those with multiple nucleoli; (2) the percentage of each phenotype is sex sp
56 ndent sequestration of the telomerase RNA in nucleoli, a process that excludes telomerase from DNA re
58 olar stress and establish the postulate that nucleoli acts as sensors of stress, regulating the cellu
61 increased protein synthesis, and report that nucleoli also expand as aging progresses in cells derive
62 eolar transcription units directly in intact nucleoli, although highly spread preparations in the ele
63 er cells depleted of NPM1 displayed deformed nucleoli and a striking rearrangement of perinucleolar h
64 luorescence that ubiquitin is present within nucleoli and also demonstrate by immunoprecipitation tha
65 regulatory events are directly regulated by nucleoli and are dependent on intact nucleolar structure
66 s associate with the fibrillar components of nucleoli and bind pre-rRNA during transcription, trigger
67 BEN domain-containing protein, localizes in nucleoli and binds to ribosomal RNA gene promoters to he
70 plex associations of both hTR and hTERT with nucleoli and Cajal bodies during S phase, implicating bo
71 is a nuclear protein localized primarily in nucleoli and Cajal bodies that was identified as a downs
74 e report that mammalian RNase H1 enriches in nucleoli and co-localizes with R-loops in cultured human
75 a-irradiation or mitomycin C, WRN leaves the nucleoli and co-localizes with the Mre11 complex in the
77 at RBS was associated with highly fragmented nucleoli and defects in both ribosome biogenesis and pro
79 is is elevated as a consequence of activated nucleoli and enhanced ribosome biogenesis in HGPS-derive
80 uded the following: (1) increased numbers of nucleoli and enlarged nuclei, (2) narrower spaces betwee
81 d insulin-like-peptide mutants exhibit small nucleoli and fibrillarin expression, as do long-lived di
82 protein colocalized with fibrillarin in the nucleoli and formed punctate structures associated with
84 nocarcinomas, leads to formation of enlarged nucleoli and increased nucleolar number in prostate lumi
85 cells from patients with HGPS have expanded nucleoli and increased protein synthesis, and report tha
86 stinfection, UXP is strongly associated with nucleoli and is found throughout the nucleus; later, UXP
88 ) is a DEAD-box enzyme that localizes to the nucleoli and may be involved in ribosomal RNA synthesis
90 ouble-labeling showed colocalization in both nucleoli and nucleoplasmic foci in breast tumor cells an
91 of MCF7 cells, BRCA1 protein dispersed from nucleoli and nucleoplasmic foci to other nucleoplasmic s
96 the cytoplasm and nucleus, concentrating in nucleoli and relocalizing to the nucleoplasm in response
97 found localization of UL84 with nucleolin in nucleoli and showed that the presence of nucleolin is in
98 has large, pleomorphic nuclei with prominent nucleoli and the cells tend to involve the entire lumen
99 protein chaperone that shuttles between the nucleoli and the cytoplasm and has been associated with
103 h binds to Mdm2 and NPM but is excluded from nucleoli and the other of which enters nucleoli but is h
104 stores, and protects ribosomal protein S9 in nucleoli and therefore could facilitate ribosome biogene
108 ng distinct longevity pathways exhibit small nucleoli, and decreased expression of rRNA, ribosomal pr
109 omatically identify lipid droplets, nucleus, nucleoli, and endoplasmic reticulum in datasets that are
111 at brat mutant cells are larger, have larger nucleoli, and have more ribosomal RNA than wild-type cel
112 ote are retained in the nucleus, localize to nucleoli, and interact with the X. laevis Box C/D RNA bi
113 , and mitochondria-rich cytoplasm, prominent nucleoli, and markers of hepatocytes and cholangiocytes.
115 lear organelles, such as Cajal bodies (CBs), nucleoli, and other nuclear bodies, is dynamic and can c
116 granular components, respectively, in active nucleoli, and partition separately into the two componen
117 ntered cells, migrated to the nucleus, bound nucleoli, and poisoned RNA biogenesis, which caused cell
118 eome, enzymatically active PP1 is present in nucleoli, and PP1gamma is highly concentrated in nucleol
120 upstream binding factor UBF-1 at interphase nucleoli, and this interaction is epigenetically retaine
126 egrity and organization of repeated DNAs and nucleoli are regulated by the H3K9 methylation and RNAi
128 autoantibodies, which frequently target the nucleoli, are pathogenic hallmarks of systemic lupus ery
130 used by steps in p53 regulation occurring in nucleoli, as suggested by some biochemical evidence.
131 [U4/U6.U5] tri-snRNP localize transiently to nucleoli, as visualized by microscopy after injection of
132 ion factor UBF1, and undergo transition into nucleoli at sites of rRNA synthesis during interphase.
133 hey have rounded cell bodies, have prominent nucleoli, attach poorly to the culture dish, and are sen
134 from nucleoli and the other of which enters nucleoli but is handicapped in binding to Mdm2 and NPM,
136 We propose that FRGY2a and YB1 disassemble nucleoli by sequestering B23, which is associated with p
137 ceous and membraneless organelles, including nucleoli, Cajal and PML bodies, and stress granules.
138 leoplasm and the density and permeability of nucleoli, Cajal bodies (CBs), and speckles in the Xenopu
140 ction of the endogenous FRG1 is localized in nucleoli, Cajal bodies, and actively transcribed chromat
142 t AgNOR-stained nucleoli, unlike H&E-stained nucleoli, can be captured and measured by an automated i
143 ing nucleocytoplasmic transport) and also in nucleoli, clearly visible against the less concentrated
145 d similar high mobility, with exclusion from nucleoli, consistent with high rates of association and
146 tion signals traffic through CBs en route to nucleoli, consistent with the role of CBs in small RNP a
149 that an Lsm2-Lsm7 protein complex resides in nucleoli, contributing to the biogenesis or function of
151 tumors revealed hypercelluarity, pleomorphic nucleoli, cytological atypia and necrosis, and positive
152 their neurotoxicity included aggregation in nucleoli, decreased number of processing bodies, and str
154 RNAs of the [U4/U6.U5] tri-snRNP localize to nucleoli, demonstrated by fluorescence microscopy of nuc
155 3R-GFP-TOP1 was markedly concentrated within nucleoli, depleted from the remainder of nucleus, and fa
158 ogy and contributes to the reorganization of nucleoli during infection.IMPORTANCE Nucleolar biology i
162 ized L5 and L11 continue to be imported into nucleoli even after nucleolar disruption and colocalize
164 ikingly, assessment of the morphology of the nucleoli exposed an abnormal nucleolar structure in Pf1-
165 arrest at morula stages of development, the nucleoli fail to differentiate and accumulation of ribos
166 come hypersensitive to micrococcal nuclease, nucleoli fail to form, and transcript levels of the copi
171 oteomic profiling of purified wild-type mESC nucleoli identified a total of 613 proteins, only ~60% o
173 distributed to the ribosomal RNA (rRNA)-rich nucleoli in cells treated with the DNA-damaging agents c
178 demonstrate that Misu translocates from the nucleoli in interphase to the spindle in mitosis as an R
179 ylated histone H3 that normally circumscribe nucleoli in oocytes and early embryos, respectively.
182 xhibited trafficking from subnuclear dots to nucleoli in response to heat-, proteotoxic- or transcrip
184 ive analysis of the molecular composition of nucleoli in skin fibroblasts and iPSC derived from them.
187 e, we demonstrate that these RNAs traffic to nucleoli independently of one another, because U4 snRNA
191 dation/alkylation in mammalian cells; within nucleoli it interacts with nucleophosmin and rRNA throug
192 nternalization and decrease in the number of nucleoli; (iv) increase in the number of pericentromeric
198 ynthesized ribosomal proteins accumulated in nucleoli more quickly than other nucleolar components.
199 for anti-RNAP I/III antibodies clearly stain nucleoli, nucleolar staining is inconsistent and cannot
200 ins, DNA, RNA, and lipids were determined in nucleoli, nucleoplasmic transcription sites, nuclear spe
203 d corneal fibroblasts, ZO-1 was localized to nucleoli of both serum-starved and serum-treated cells.
205 The Raman maps show the nucleus and the nucleoli of cells as well as subcellular organization in
207 1 protein (which localizes to the nuclei and nucleoli of cells) interacts with both IRS-1 and the SV4
208 a novel protein, nucleostemin, found in the nucleoli of CNS stem cells, embryonic stem cells, and se
210 ntrast, it colocalized with nucleolin in the nucleoli of corneal fibroblasts after serum-starved cell
211 In Xenopus somatic cell nuclear cloning, the nucleoli of donor nuclei rapidly and almost completely d
213 lysis for Raman spectra measured in the same nucleoli of HeLa cells before and after fixation by eith
214 -fluorescein stains the cytosol, nuclei, and nucleoli of HeLa cells under conditions where the Ru-oct
216 ucleolar RNA-TAR decoy that localizes to the nucleoli of human cells and colocalizes in the nucleolus
218 (ANG) protein, which entered the nuclei and nucleoli of infected cells and stimulated 45S rRNA gene
219 also observed an accumulation of Gag in the nucleoli of infected cells derived from mammary gland tu
224 romolecules and protein conformations in the nucleoli of iPSC and human embryonic stem cells (hESC) w
225 cleolar disassembly, FRGY2a localized to the nucleoli of isolated nuclei and was capable of disassemb
228 Our earlier report that BIG1 concentrated in nucleoli of serum-starved HepG2 cells prompted us to ide
229 ids and protein conformations indicates that nucleoli of skin fibroblasts contain similar subsets of
233 e staining patterns partially overlap in the nucleoli, promotes ATF5 protein degradation through prot
234 interaction of IRS-1, PI3-K, and UBF1 in the nucleoli provides one of the mechanisms for the effects
235 ed in over 4500 human proteins from purified nucleoli, providing enhanced coverage of the nucleolar p
236 al and proteomics approaches to characterize nucleoli purified from cultured human and mouse cells.
239 associated with heterochromatic regions and nucleoli, respectively, where yeast Sir2 functions; 2) S
242 ymerase III (Pol III)-transcribed genes with nucleoli seems to be an evolutionarily conserved propert
244 umulated multiple kinetoplasts, flagella and nucleoli, similar to the effects of RNAi-dependent knock
246 ei and was capable of disassembling purified nucleoli, suggesting a direct interaction between FRGY2a
248 ted TDP-43 was specifically recruited to the nucleoli, suggesting that p-T153/Y155 regulates a previo
251 asmic shuttling protein, mainly localized at nucleoli, that plays a key role in several cellular func
252 asmic shuttling protein, mainly localized at nucleoli, that plays a number of functions in ribosome b
253 l CRs toward both the nuclear border and the nucleoli, the former being enhanced in nonproliferating
255 markers for organelles or regions, including nucleoli, the nuclear envelope, nuclear speckles, centro
256 mponents of membrane-less organelles such as nucleoli, the nuclear pore complex and stress granules.
258 t mutually exclusive) hypothesis centered on nucleoli: the specialized intranuclear domains within wh
259 red region prevents TOP1 binding to sites in nucleoli, thus driving it to bind in the nucleoplasm; an
260 e various histologic methodologies for using nucleoli to assess the malignant potential of uveal mela
265 Co-migration of RNase H1 and R-loops from nucleoli to perinucleolar ring structures was observed u
266 ction and recruitment of heterochromatin and nucleoli to the nuclear lamina facilitates the folding o
268 localization of NPM1 and BER components from nucleoli to the nucleoplasm, and cellular experiments ta
269 viously been demonstrated that AgNOR-stained nucleoli, unlike H&E-stained nucleoli, can be captured a
272 ion of newly expressed NHPX from speckles to nucleoli was dependent on RNA polymerase II transcriptio
273 nt accumulation of NHPX in speckles prior to nucleoli was observed in multiple cell lines, including
277 lular fractionation, virions accumulating in nucleoli were found to retain infectivity in secondary i
280 dering a recent finding that, in dead cells, nucleoli were targeted by C1q and two nucleolar autoanti
283 These data show that mTORC1 is located in nucleoli where it acts to regulate events involved in ri
284 found in different subcellular compartments-nucleoli, where it associates with ribosomal RNA and is
285 ate 1 (IRS-1) translocates to the nuclei and nucleoli, where it binds to the upstream binding factor
286 mponents raptor and mTOR are both present in nucleoli, where they may regulate rRNA maturation events
287 ary for the localization of c-Myc protein to nucleoli, whereas c-Myc nucleolar localization is indepe
288 eLa cells, DmNopp140-RGG localizes to intact nucleoli, whereas DmNopp140 partitions HeLa nucleoli int
289 primarily nuclear and largely excluded from nucleoli, whereas PP1gamma and to a lesser extent PP1bet
290 abidopsis thaliana are present within sorted nucleoli, whereas silenced rRNA genes are excluded.
291 GFP fusion protein localized specifically to nucleoli, whereas the N-terminal sequence of SelH fused
294 53 by release of ribosomal proteins from the nucleoli, which bind to MDM2 and inhibit p53 degradation
295 sulting in misdirection of telomerase RNA to nucleoli, which prevents telomerase from elongating telo
298 firmed that nucleolin localizes primarily to nucleoli with RNA polymerase I, we demonstrated that nuc
299 ions, profile counts in paraffin sections of nucleoli within a nucleus were 36% greater in 100-day-ol
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