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1 of calf spleen and human erythrocyte purine nucleoside phosphorylase.
2 the ribosylated metabolites by human purine nucleoside phosphorylase.
3 2-amino-6-mercapto-7-methylpurine by purine nucleoside phosphorylase.
4 ated effect was dependent on the DeoD purine nucleoside phosphorylase.
5 ve NP, it was widely inferred to be a purine nucleoside phosphorylase.
6 e (dGK) or degraded in the cytosol by purine nucleoside phosphorylase.
7 it is a tight inhibitor (Kd 12 nM) of purine nucleoside phosphorylase.
8 nce such as nucleoside hydrolases and purine nucleoside phosphorylases.
9 catalyzed by P. falciparum and human purine nucleoside phosphorylases.
10 e monophosphate kinase, 3.2-fold; pyrimidine nucleoside phosphorylase 3.6-fold) in resistant cells.
11 ne can rescue cultured parasites from purine nucleoside phosphorylase and adenosine deaminase blockad
12 ins as transition state analogues for purine nucleoside phosphorylase and characterized them with the
13 hatase, 5'-nucleotidase cytosolic-II, purine nucleoside phosphorylase and xanthine oxidase) was perfo
14 d with a combination of adenosine deaminase, nucleoside phosphorylase and xanthine oxidase, the senso
15 urines when both human and Plasmodium purine nucleoside phosphorylases and adenosine deaminases are i
16 onversions by adenosine deaminase and purine nucleoside phosphorylase, and it displayed limited oral
17 s established that uridine hydrolase, purine nucleoside phosphorylase, and methylthioadenosine phosph
23 anilate phosphoribosyltransferase (TrpD) and nucleoside phosphorylase class II enzymes but bind with
24 that uridine hydrolase and mammalian purine nucleoside phosphorylase cleave nicotinic acid riboside,
25 is measured using the pyrophosphatase-purine nucleoside phosphorylase coupling system with the chromo
28 ate structures of human and bovine of purine nucleoside phosphorylases differ, despite 87% homologous
32 ated guanosine analogues catalyzed by purine nucleoside phosphorylase has been analyzed to understand
33 upstream) and two ORFs representing a purine nucleoside phosphorylase homolog and tpp15, a previously
34 Crystallographic studies of human purine nucleoside phosphorylase (hPNP) with several transition-
35 -> Glu and His(104) --> Arg) in human purine nucleoside phosphorylase (hPNP), there is an enhancement
38 uanosine, suggesting involvement of a purine nucleoside phosphorylase in the nucleoside protective ef
39 The coding sequence annotated as a putative nucleoside phosphorylase in the Trypanosoma cruzi genome
42 Treatment of cultures with BCX-34, a purine nucleoside phosphorylase inhibitor, prevented protection
44 The transition-state structure for purine nucleoside phosphorylase is characterized by (1) an elev
45 n of transition-state inhibitors with purine nucleoside phosphorylase is different from reactant-stat
46 ective for malarial relative to human purine nucleoside phosphorylase, kills P. falciparum in culture
48 y and biochemically characterized a putative nucleoside phosphorylase (NP) from the pathogenic protoz
50 e P. falciparum purine salvage enzyme purine nucleoside phosphorylase (PfPNP) is a potential drug tar
51 rate binding site is unlike that from purine nucleoside phosphorylase, phosphoribosyltransferases, or
53 athway consisting of a bacterial type purine nucleoside phosphorylase (PNP) and a purine nucleoside k
54 urine salvage system, consisting of a purine nucleoside phosphorylase (PNP) and a purine nucleoside k
55 transition-state analogues for bovine purine nucleoside phosphorylase (PNP) and are the most powerful
57 ensitive to a purine salvage block at purine nucleoside phosphorylase (PNP) and that human PNP is a t
64 sition path sampling study with heavy purine nucleoside phosphorylase (PNP) characterized the experim
66 sociated protein, 70 kDa (ZAP70), and purine nucleoside phosphorylase (PNP) deficiencies had low resp
73 cture of SsMTAP is similar to that of purine-nucleoside phosphorylase (PNP) from Escherichia coli, ho
74 in which the dual specificity enzyme purine nucleoside phosphorylase (PNP) functions in both purine
75 competitive inhibitors of calf spleen purine nucleoside phosphorylase (PNP) have been determined empl
76 bose 1-phosphate (R1P) bound to human purine nucleoside phosphorylase (PNP) have been studied by FTIR
77 ential inhibitors of glycosidases and purine nucleoside phosphorylase (PNP) have been synthesized via
87 evaluated as potential inhibitors of purine nucleoside phosphorylase (PNP) isolated from peripheral
88 bitol] is a 23 pM inhibitor of bovine purine nucleoside phosphorylase (PNP) specifically designed as
90 tate analogue inhibitors of mammalian purine nucleoside phosphorylase (PNP) that induce purine-less d
91 lso armed with the prodrug convertase purine nucleoside phosphorylase (PNP) that locally converts the
93 The X-ray crystal structures of human purine nucleoside phosphorylase (PNP) with bound inosine or tra
94 cies of adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP), result in defective lymp
95 nzymes in its purine salvage pathway, purine nucleoside phosphorylase (PNP), shows physical propertie
104 uanines) are inhibitors of the enzyme purine nucleoside phosphorylase (PNPase) with Ki' values rangin
106 A structural genomics comparison of purine nucleoside phosphorylases (PNPs) indicated that the enzy
107 Additionally, mycoplasma-derived pyrimidine nucleoside phosphorylase (PyNP) activity indirectly pote
109 own of the guanosine to guanine using purine nucleoside phosphorylase, the ammonia formed as a result
110 of the transition-state structure of purine nucleoside phosphorylase were synthesized and tested as
112 is limitation by employing the enzyme purine nucleoside phosphorylase with substrate 7-methylguanosin
113 standing the evolution of uridine and purine nucleoside phosphorylases with respect to DNA/RNA metabo
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