ライフサイエンスコーパス: nucleotide triphosphate

1 alance between binding and hydrolysis of the nucleotide triphosphate.

2 g site decreased the binding affinity of the nucleotide triphosphate.

3 dT) paired with an incoming dNTP or modified nucleotide triphosphate.

4 with the equivalent fluorescent dye-labeled nucleotide triphosphate.

5 groups that bind the beta phosphate group of nucleotide triphosphate.

6 f nucleotides and a dimer in the presence of nucleotide triphosphate.

7 the beta- and gamma-phosphate groups of the nucleotide triphosphate.

8 observe a requirement for hydrolysis of any nucleotide triphosphate.

9 ted by the addition of ATP and several other nucleotide triphosphates.

10 ivity for binding to the naturally occurring nucleotide triphosphates.

11 dal in the presence of low concentrations of nucleotide triphosphates.

12 nhibited by micromolar concentrations of all nucleotide triphosphates.

13 y was supported by ATP or dATP but not other nucleotide triphosphates.

14 e the affinity of ARF for activating guanine nucleotide triphosphates.

15 on step and discrimination between different nucleotide triphosphates.

16 AD dependence of repressor activity required nucleotide triphosphates.

17 in kinase inhibitor (PKI), or they may mimic nucleotide triphosphates.

18 purine-labeled DNA substrates, 2-aminopurine nucleotide triphosphate, a nonhydrolyzable nucleotide an

19 nger RNA half-lives, and the availability of nucleotide triphosphates, amino acids, RNA polymerase, a

20 ating incremental truncation libraries using nucleotide triphosphate analogs.

21 ervable effect, but ATPgammaS and GTPgammaS, nucleotide triphosphate analogues resistant to Hsp70 hyd

22 is followed by the reversible hydrolysis of nucleotide triphosphate and subsequent conformational tr

23 s strongly dependent on both the nature of a nucleotide triphosphate and that of a divalent metal.

24 and adenosine triphosphate or analogs of the nucleotide triphosphate and then analyzed by matrix-assi

25 The new assay principle uses only natural nucleotide triphosphates and avoids a labour-intensive f

26 Moreover, this step required both nucleotide triphosphates and cytosol.

27 al pathways by which 8-oxodG is converted to nucleotide triphosphates and incorporated into both DNA

28 cle intermediates, but they strongly deplete nucleotide triphosphates and may impede nucleotide synth

29 d contains small pores that permit influx of nucleotide triphosphates and metabolites of nucleoside a

30 ese advantages, diene- and cyclohexene-based nucleotide triphosphates are expected to find wider use

31 The respective nucleotide triphosphates are substrates for some DNA pol

32 esis of the hrpA regions predicted to encode nucleotide triphosphate binding and hydrolysis functions

33 Here we demonstrate how nucleotide triphosphate binding free energy can rectify

34 HsORC4 has a putative nucleotide triphosphate binding motif that is not seen i

35 hanges in conformation that subtly alter the nucleotide triphosphate binding site such that ddNTPs be

36 Mutations were made in the predicted nucleotide triphosphate-binding domain, confirming the a

37 the first four AAA domains contain consensus nucleotide triphosphate-binding motifs, or P-loops.

38 chicken mitochondrial CK indicates that its nucleotide triphosphate-binding site indeed contains the

39 porate one or, at most, a few biotin-labeled nucleotide triphosphates (biotin-NTPs) into the 3' end o

40 irectly examine G protein conformations with nucleotide triphosphates bound, we synthesized several n

41 ational targeting and translocation requires nucleotide triphosphates but not cytosolic proteins.

42 op activity was observed in the absence of a nucleotide triphosphate cofactor, indicating that the co

43 by single-stranded DNA in the presence of a nucleotide triphosphate cofactor, it mediates cleavage o

44 doxorubicin are potent (low-microM) DNA- and nucleotide triphosphate-competitive priming inhibitors t

45 ures capturing the active polymerase and its nucleotide triphosphate complexes in four distinct state

46 The nucleotide triphosphate concentrations required at the T

47 n which the radioactive gamma-phosphate of a nucleotide triphosphate could transfer to a photoactivat

48 binding free energies for a free deoxyribose nucleotide triphosphate, dATP or dGTP, to Pol eta comple

49 ic degradation of canonical and noncanonical nucleotide triphosphates (dNTPs).

50 sition of the RNA template and the substrate nucleotide triphosphates during initiation and elongatio

51 ficity and concentration requirements of the nucleotide triphosphate effect suggests a P2X(7) recepto

52 ed a strong positive correlation with TUNEL; nucleotide triphosphate/EPP showed a strong negative cor

53 brain (31)P magnetic resonance spectroscopy nucleotide triphosphate/exchangeable phosphate pool.

54 entration of CTP, the predominant initiating nucleotide triphosphate for this promoter.

55 For example, nucleotide-triphosphates generate nucleotide-diphosphate

56 The small guanine nucleotide triphosphate (GTP)-binding protein RhoA stimu

57 nducibility compared with GTP, whereas other nucleotide triphosphates had no effect.

58 For nucleotide triphosphates, however, mixtures of acidic (0

59 t the first two folds, the P-loop containing nucleotide triphosphate hydrolase and the NAD(P)-binding

60 fold structure typical of P-loop containing nucleotide triphosphate hydrolases.

61 limitation because ATP is the most abundant nucleotide triphosphate in the cell, and Mg(2+) is also

62 Stoichiometric binding of these nucleotide triphosphates in PRK's substrate site is obse

63 uantified the levels of serum uridine and of nucleotide triphosphates in the liver, spleen, and lymph

64 sence of magnesium, but becomes specific for nucleotide triphosphates in the presence of manganese.

65 sphoenolpyruvate which together maintain the nucleotide triphosphates in the reaction mixture.

66 movement of the bridge helix that helps load nucleotide triphosphates into the active site.

67 products by substitution of the appropriate nucleotide triphosphates into the reaction.

68 In addition, the respective nucleotide triphosphate is accepted as a substrate by th

69 ally applicable to reactions involving other nucleotide triphosphates is described.

70 Oligomers could be converted to dimers by nucleotide triphosphate-Mg, and nucleotide release from

71 Motifs "A" and "B" are involved in nucleotide triphosphate (NTP) binding and hydrolysis, wh

72 f promoter open complexes and the effects of nucleotide triphosphate (NTP) concentration on the effic

73 At low nucleotide triphosphate (NTP) concentrations, we observe

74 coil to a helical hairpin that contacts the nucleotide triphosphate (NTP) substrate to allow rapid n

75 for elongation and apparent K(m) values for nucleotide triphosphate (NTP) use.

76 hosphomonoesters, inorganic phosphate, gamma-nucleotide triphosphate (NTP), and beta-NTP were measure

77 ge proteins characterized by an NH2-terminal nucleotide triphosphate (NTP)-binding domain, two long s

78 The nucleotide triphosphate (NTP)-driven translocation hypot

79 vershoot (measured absolutely or relative to nucleotide triphosphate, NTP) following HI has been obse

80 ase of MANT ADP, where T, D, and Pi refer to nucleotide triphosphate, nucleotide diphosphate, and ino

81 ep Vent (exo(-)) DNA polymerase accepted the nucleotide triphosphate of C-nucleotide 6 as a substrate

82 hat the RecA-catalyzed hydrolysis of a given nucleotide triphosphate or analogue thereof is exquisite

83 etal muscle were observed in the presence of nucleotide triphosphates or diphosphates but not AMP, cA

84 ir 2-deoxy forms (collectively designated as nucleotide triphosphates or NTPs) as contractile substra

85 A noticeable preference for nucleotide triphosphates over nucleotide diphosphates an

86 These nucleotide triphosphate preferences should have ramifica

87 Unlike mutT, a gene for another conserved nucleotide triphosphate pyrophosphohydrolase that functi

88 humb domain to create a tunnel through which nucleotide triphosphates reach the active site.

89 nzymes are similar, their aminoglycoside and nucleotide triphosphate substrate profiles are distincti

90 esistance profile and the aminoglycoside and nucleotide triphosphate substrate profiles of four commo

91 d the other can utilize either ATP or GTP as nucleotide triphosphate substrate.

92 When trinitrophenyl-ATP, a fluorescent nucleotide triphosphate that functions as an alternative

93 Compared to those of the other hydrolyzable nucleotide triphosphates, the ATPase activity of Lon is

94 Among nucleotide triphosphates, the order is ATP > CTP approxi

95 For binding to the nucleotide triphosphates, the order of binding affinity

96 KRas bound to its corresponding enantiomeric nucleotide triphosphate, this study sets the stage for f

97 te of the active RecA protein using modified nucleotide triphosphates to discern key structural eleme

98 nsferases that couple sugar-1-phosphates and nucleotide triphosphates to form Leloir pathway glycosyl

99 e (10 units/ml), which rapidly hydrolyzes 5' nucleotide triphosphates to monosphophates, prevented th

100 er of the effectiveness of the corresponding nucleotide triphosphates to support force production in

101 kinase, which would transfer phosphate from nucleotide triphosphates to the GDP bound to Gk, produci

102 we show that an exogenously expressed algal nucleotide triphosphate transporter efficiently imports

103 The global regulation of nucleotide triphosphate turnover by intracellular Mg(2+)

104 he rate of transcription on concentration of nucleotide triphosphate, we infer that the combed DNA mo

105 e activity was specific for polynucleotides; nucleotide triphosphates were not hydrolyzed.

106 Radiolabeled nucleotide triphosphates were used to confirm the desire

107 us studies suggested that the interaction of nucleotide triphosphate with CFTR at ATP-binding site 2

108 sults also suggested that the interaction of nucleotide triphosphate with CFTR at ATP-binding site 2

109 ation with complete substitution of all four nucleotide triphosphates with phosphorothioates or the s