ライフサイエンスコーパス: null

1 , bias was usually <10% (downward toward the null).

2 d errors have correct type I error under the null.

3 estimates were imprecise and centered on the null.

4 frequently imprecise or consistent with the null.

5 causal effects even when the true effect was null.

6 ociated with mGluR6 or alpha-DG in the Lamb2-null.

7 it of the confidence interval closest to the null.

8 odel reduced the linkage signal to virtually null.

9 will be systematically biased away from the null.

10 s undetectable in mutants nanA-null and msgA-null.

11 in the postintervention period were close to null.

12 experiments in Caenorhabditis elegans unc-18 nulls.

13 uced Ca(2+) transients elicited in dysferlin-null A/J myofibres were smaller than control A/WySnJ fib

14 However, prior to depletion, Pten-null activated SCs can transiently proliferate upon inju

15 We found that all DutNM1 null activity mutants interacted with the SaPIbov1 Stl C

16 Furthermore, mice heterozygous for a null allele of Nrip1 showed a CAKUT-spectrum phenotype.

17 omozygous or heterozygous for the Tau (Mapt) null allele were found to exhibit increasing levels of a

18 isely delete foraging, generating the for(0) null allele, and used recombineering to reintegrate a fu

19 n this study, we generated an inducible Drd2 null-allele mouse strain that circumvented developmental

20 Null-allele test on cDNA from patients' fibroblasts of b

21 Null alleles (sgb11/esk1-7) of ESK1 restore to wild-type

22 Overall, given the null alleles and phenotypic assays used, we did not find

23 nic Kras allele (Kras(mut) ) and conditional null alleles of Apc and Trp53 (iKAP).

24 Two independent null alleles revealed that Copb2 is essential for early

25 llagen V, and is most often caused by COL5A1 null alleles.

26 TPA suppression, indicating they function as null alleles.

27 , we analyzed collagen cross-links in Fkbp10-null and -wild-type murine embryonic fibroblasts.

28 ng the potential harm to patients under both null and alternative hypotheses using NCI and Alliance d

29 rm to current and future patients under both null and alternative hypotheses.

30 yses on neural tubes isolated from E9.0 EpoR-null and littermate control embryos validated our in vit

31 ILY in FBS was undetectable in mutants nanA-null and msgA-null.

32 gative effects, and five (5%) suggested both null and negative effects.

33 ssential protein domains, (4) generates both null and other informative alleles.

34 , by studying the behavior of SVs and EEs in null and rigor mutants of kinesin-3 and kinesin-1 (UncA

35 serum IgE levels were compared in claudin-18 null and wild-type mice following aspergillus sensitizat

36 V600E) inhibitor PLX4720 in both BVE(Cyp24a1-null) and BVE(Cyp24a1-wt) cells.

37 city was compared among wild-type, Cyp2abfgs-null, and CYP2A13/2F1-humanized mice following inhalatio

38 TSC2-null tumor cells and immortalized TSC2-null angiomyolipoma cells, but not in cells with intact

39 ependent inhibition can be rescued in npr-19-null animals by the expression of a human cannabinoid re

40 rtholog TBPH, we previously showed that TBPH-null animals display locomotion defects as third instar

41 Null animals survive to larval and pupal stages due to a

42 These mice phenocopied Ifnlr1-null animals, exhibiting increased intestinal tissue tit

43 nduces increased NSC proliferation, and CD44-null as well as HA-disrupted wild type NSCs demonstrate

44 We observed null associations for boys and early-childhood adiposity

45 variate-adjusted standardization resulted in null associations observed between arsenic concentration

46 propriate statistical methodology, we report null associations.

47 are much higher than those compatible with a null assumption that preserves the empirically observed

48 with the smallest possible central intensity null at XUV wavelengths.

49 In addition, experiments with Btk-null B cells revealed off-target effects of ibrutinib on

50 a GFP-tagged phospho-dead S193A allele on a null background (Atoh1(S193A/lacZ)) exhibit mild cerebel

51 he liver FA binding protein null or Apobec-1 null background (i.e., apolipoprotein B100 only) exhibit

52 ed mutant CaV2.1 alpha1 subunits on a CaV2.1 null background at the calyx of Held presynaptic termina

53 TV-Cre-mediated Cbl gene deletion on a Cbl-b null background, as well as a tamoxifen-inducible mammar

54 renin locus was crossed onto the mouse Ren1d-null background, restoring granulation in juxtaglomerula

55 by expressing a tagged copy of TbRFT1 in the null background.

56 cei, enabling the study of its function in a null background.

57 and stem cell factor in a NOD/SCID-IL2Rgamma(null) background (NSGS mice), we demonstrate remarkable

58 In contrast, in the Lamb2-null, beta-dystroglycan (beta-DG) expression is altered,

59 demonstrate that the African-specific Duffy-null blood group-believed to confer resistance against P

60 biquitination of NUMBL is diminished in TAK1-null BMMs compared to elevated K48-poly-ubiquitination i

61 iting technology, and alleles designed to be null can express aberrant proteins.

62 e rapid cell proliferation compared with p53-null cancer cells, the mechanism for dependency of tumor

63 nt with an essential function for ME3 in ME2-null cancer cells.

64 en(-/-) mouse embryonic fibroblasts and PTEN-null cancer cells.

65 METHODS AND We compared a VEC-null cell line with the same line reconstituted with VEC

66 Flp recombinase to restore expression in two null cell lines to demonstrate how our system confirms c

67 Conversely, LKB1-overexpression in LKB1-null cells abrogated invasion, migration and mammosphere

68 alyses of BITC-treated xenografts using LKB1-null cells corroborate in vitro mechanistic findings and

69 Deletion of CUL9 in p53 null cells does not lead to further increase of DNA dama

70 We found that Twist1-null cells expressed high levels of the T cell chemoattr

71 duced fluorescence near the levels in GABAAR-null cells indicating that FMR-Red-Dye, a barbiturate de

72 the basic actin machinery was intact, Cdc42 null cells lacked the ability to polarize their Golgi an

73 Inhibition of uPA expression in Tsc2-null cells reduced the growth and invasiveness and incre

74 1, and >18 mM, respectively), whereas GABAAR-null cells were unresponsive.

75 C-NAP1-null cells were viable and had an increased frequency of

76 Reconstitution of PTEN-null cells with either wild-type PTEN or a catalytically

77 HspB1-null cells, generated by CRISPR/Cas9 nuclease genome edi

78 ium membrane potentials compared with GABAAR-null cells.

79 rmalized in PLCgamma1/DAG kinase zeta double null cells.

80 enic FANCI-, FANCD2- and FANCI:FANCD2 double-null cells.

81 e restores autophagic cell death in Bax/Bak1 null cells.

82 -dependent repression, as confirmed in Dicer-null cells.

83 iched repressive nuclear compartments in p63-null cells.

84 t decrease cell proliferation in BVE(Cyp24a1-null) cells, it strengthened antitumor responses to the

85 icating increased stability of NUMBL in TAK1-null conditions.

86 Lepr-null control males and females were morbidly obese and e

87 d nasal olfactory mucosa (OM) from Cyp2abfgs-null, CYP2A13-humanized, and CYP2A13/2F1-humanized mice.

88 ent both preferred direction enhancement and null direction suppression.

89 etabolite) were no more coexpressed than the null distribution for neighboring genes.

90 ls of the linear mixed model to estimate the null distribution of the Fisher combination test statist

91 r mutants, we infer that Reln(CTRdel)/Apoer2(null) double homozygotes have both receptor pathways dis

92 minimal value of HR for PFS to predict a non-null effect on OS.

93 vi5l expression is increased in Tgif1; Tgif2-null embryos and in double-null mouse embryo fibroblasts

94 novel imaging approach to analyze Cyclin B1-null embryos from fertilization onward.

95 domains expand in Ehmt1 (also known as Glp) null ESCs, revealing that H3S10ph deposition is restrict

96 d by its ability to retrieve an unconfounded null estimate after adjustment in this pseudo-population

97 homozygous deletion of Cyp24a1 (BVE(Cyp24a1-null)) exhibited a 4-fold reduction in tumor growth.

98 JDP2 null females had increased levels of circulating FSH and

99 NOTCH receptor, is downregulated in the PTEN-null fibroblasts leading to a loss in the paracrine acti

100 ction of JAGGED-1 expression within the PTEN-null fibroblasts was sufficient to abrogate the observed

101 l Perspectives Companion Paper: Should a Few Null Findings Falsify Prefrontal Theories of Conscious P

102 In Notum null flies, we find upregulated extracellular Wg ligand

103 prevented on a high-protein diet and in FoxO-null flies.

104 Fibronectin stimulation in null FlnA cells impairs enhanced spreading whereas FlnB

105 ave also shown that female mice homozygously null for ALADIN are sterile.

106 Mice null for pRb, p107, p130 or any combination of double mu

107 Furthermore, mice null for two components of IL1beta signaling, the type 1

108 P) detectors, has the potential to eliminate null functions.

109 pression was decreased in laminin-alpha2 dyW null gastrocnemius muscle.

110 Null hei10 mutants are haploinsufficient, and, using gen

111 Survival rates of Ret wild-type, null heterozygote and null homozygote mice at E12.5, bir

112 ates of Ret wild-type, null heterozygote and null homozygote mice at E12.5, birth and weaning were no

113 d efferent fibre activation were balanced, a null HRR was evoked (defined as 'neural fulcrum') during

114 Re-expression of PAX2 in PAX2-null human HGSC cells reduced cell survival via apoptosi

115 RP are transcriptionally up-regulated in p53-null human tumors.

116 a realistic range of prior probabilities for null hypotheses, false report probability is likely to e

117 er 219 (41%) deaths had occurred to test the null hypothesis of no efficacy (threshold for rejection

118 Without discarding the culture of null hypothesis significance testing and implementing th

119 n of results for further evaluation based on null hypothesis significance testing is doomed to yield

120 s a primary culprit, which is the culture of null hypothesis significance testing that dominates stat

121 bility in science stem from our "culture" of null hypothesis significance testing.

122 ishing a [Formula: see text] value under the null hypothesis that it was chosen from a stationary dis

123 the alternative hypothesis to that under the null hypothesis.

124 basis for doing so, as when testing only the null hypothesis; and 3) statistical reification, treatin

125 Null-hypothesis testing is also discussed.

126 sing the correlation coefficient to test the null-hypothesis, which avoids the costly computation of

127 The recessive and functionally null I/LnJ H2-Ob allele supported the production of viru

128 n the IL2 receptor common gamma chain (IL2rg(null)) in the early 2000s, investigators have been able

129 malate concentrations in the xylem sap than nulls, indicating greater concentrations of malate in th

130 Vivax infections in Duffy-null individuals have suggested the evolution of alterna

131 compared with wild-type infected mice, CD151-null infected mice exhibited a significant reduction in

132 d genes and genes downregulated in Hnf1alpha-null islets and Nkx2.2-null islets, among others.

133 egulated in Hnf1alpha-null islets and Nkx2.2-null islets, among others.

134 of H3K27 at loci downregulated in Hnf1alpha-null islets.

135 proangiogenic roles for alpha3beta1, alpha3-null keratinocytes showed reduced paracrine stimulation

136 pidermal initiating signals produced by DLX3-null keratinocytes, we performed acute deletion of DLX3

137 We propose a bivariate null kernel (BNK) hypothesis testing method, which chara

138 ignificantly increased in the laminin gamma3-null (Lamc3(-/-)) retinal superficial vascular plexus an

139 ective loss of the long 3'UTR mRNA in CaMKII-null larvae allows us to test its role in plasticity.

140 Low density lipoprotein receptor-null (Ldlr(-/-)) mice on a high-fat diet were orally adm

141 during regeneration but more notably in AhR-null livers.

142 , and reduced hepatic differentiation in Mgp-null lungs.

143 ed cells, but partially rescued in FABP4/aP2-null macrophages when UCP2 is silenced.

144 Transcriptome profiling of E2F-2-null, mature erythroblasts demonstrated widespread chang

145 However, unlike Rac1 knockouts, Cdc42 null melanoblasts were elongated and displayed large, bu

146 hibiting tumor growth in the BRAF V600E/PTEN-null melanoma mouse model.

147 ndent STAT3 phosphorylation, with E-cadherin null mESCs exhibiting over 3000 gene transcript alterati

148 Here, AhR-null mice (AhR-/-) were used to explore whether AhR cont

149 y, expression of Mg29 in the hearts of Csrp3 null mice (encoding muscle LIM protein, MLP) partially r

150 rmline liver fatty acid (FA) binding protein null mice (Mttp-LKO, i.e., double knockout mice) hepatic

151 Upf3b-null mice also have a profound defect in prepulse inhibi

152 dney epithelial cells derived from both Pkd1-null mice and ADPKD patients.

153 By using intravital microscopy with DREAM-null mice and their bone marrow chimeras, we demonstrate

154 Moreover, because RIAM-null mice are healthy, fertile, and display no bleeding

155 hmt (betaine-homocysteine methyltransferase)-null mice at age 4, 12, 24, and 52 wk (N = 8) and observ

156 d found to be significantly delayed in Cox-1 null mice at term.

157 Ptrh2 null mice demonstrate multiple degenerating and regenera

158 Strikingly, these conditional gp96-null mice developed spontaneous colitis, had increased l

159 As Alpl-null mice die before weaning, we aimed to generate mouse

160 Similar to Rac1 knockouts, Cdc42 null mice displayed a severe loss of pigmentation, and m

161 Notably, Kv3.1-null mice displayed baseline hyperlocomotion, reduced an

162 Compared with wild-type mice, NgR123-null mice had a sharp increase in the glial marker glial

163 At 12 months of age, P2X7-null mice had thickening of Bruchs membrane and retinal

164 ZnT8 null mice have a mild phenotype with a slight decrease i

165 In addition, neural stem cells from Upf3b-null mice have impaired ability to undergo differentiati

166 transplantation from platelet-specific ERK5 null mice into hyperlipidemic apolipoprotein E null mice

167 n MDM2-ALT1 is ubiquitously expressed in p53 null mice it leads to increased incidence of spindle cel

168 ophagy, but these effects are blunted in SHP-null mice or LSD1-depleted mice.

169 Consistent with these data, caveolin-1-null mice overexpressing K-Ras(G12D) display accelerated

170 Furthermore, MDM2-ALT1-expressing p53 null mice represent a novel mouse model of fusion-negati

171 on of specific DNA loci in the liver of Bhmt-null mice results in repression of Iqgap2 and F2rl2 and

172 Experiments in Fmr1 null mice show that FMRP regulates axonal protein expres

173 ll mice into hyperlipidemic apolipoprotein E null mice showed decreased platelet accumulation and inc

174 ium-phosphate cotransporter Npt2a in alphaKL-null mice supporting direct actions of cKL in the absenc

175 ted, streptozotocin-treated ghrelin receptor-null mice that were administered GcgR monoclonal antibod

176 Male wild-type (WT) and Cyp2e1-null mice were fed standard chow or FF for 2, 12, and 24

177 omain of CIZ1 and the E repeats of Xist CIZ1-null mice, although viable, display fully penetrant fema

178 of cell death in intestinal tissue of cIAP1-null mice, compared with wild-type C57BL/6 mice, cIAP2-n

179 urrent is absent in cochlear cells of Piezo2-null mice, even though the normal MT current persists.

180 Female JDP2 null mice, however, exhibited early puberty, observed as

181 compared with wild-type C57BL/6 mice, cIAP2-null mice, or XIAP-null mice.

182 In RTN3-null mice, RTN1 expression was slightly elevated.

183 wed greater sensitivity to NA than Cyp2abfgs-null mice, with greater depletion of nonprotein sulfhydr

184 econstitute the vascular dysfunction in CD36-null mice.

185 ce but are profoundly impaired in BK channel-null mice.

186 of Whsc1 prevented tumor progression in PTEN-null mice.

187 PPARgamma suppression causes alopecia in VDR-null mice.

188 icantly increased in Mybphl heterozygous and null mice.

189 autophagy inhibition is attenuated in FGF15-null mice.

190 d on OL progenitor cells purified from Thap1 null mice.

191 eased rate of arrhythmia in heterozygous and null mice.

192 -type C57BL/6 mice, cIAP2-null mice, or XIAP-null mice.

193 Ldlr(-/-) (low-density lipoprotein receptor null) mice transplanted with bone marrow (BM) cells from

194 enotype seen in the cerebral cortex of Vldlr(null) mice.

195 xEnt, and then using this MaxEnt theory as a null model against which to compare mechanistic predicti

196 ective theories of language change against a null model and reveals an underappreciated role for stoc

197 ly different from the expectations under the null model that some speciation process should be invoke

198 on model's forecast horizon against a simple null model.

199 istinguishable from patterns arising under a null model.

200 y compared with those obtainable with simple null models of diversification under stochastic lineage

201 Unlike in the conditional adult Runx1 null models, megakaryocytic maturation is not affected i

202 d in Tgif1; Tgif2-null embryos and in double-null mouse embryo fibroblasts (MEFs).

203 ne 27 trimethylation (H3K27me3) in both Pten null mouse embryonic fibroblasts (MEFs) and Pten null mo

204 By contrast, Pou5f1-null mouse embryos maintained the expression of ortholog

205 Sox6-null mouse fetuses present misshapen and nucleated eryth

206 Using a syngeneic TP53-null mouse model of breast cancer, we identified distinc

207 mouse embryonic fibroblasts (MEFs) and Pten null mouse prostate tissues.

208 ly detected abnormal remodeling in the Cox-1 null mouse, and clearly demonstrated that the cervix pla

209 ific epidermal growth factor receptor (EGFR) null mouse, we show that exendin-4 induced an increase i

210 In a PTEN-null murine PCa model, WHSC1 overexpression in prostate

211 nally, the organoid-forming capacity of Spop-null murine prostate cells was more sensitive to c-MYC i

212 2 expression is decreased in alpha7 integrin null muscle.

213 PME gene T-DNA insertion lines revealed two null mutant alleles of PME34 (At3g49220) that both consi

214 trioles in delta-tubulin and epsilon-tubulin null mutant human cells lack triplet microtubules and fa

215 In contrast, a null mutant in gamma34.5 failed to control IRF3 phosphor

216 An isogenic codY-null mutant of SM101 showed decreased levels of spore fo

217 d explains the aetiology of the even-skipped null mutant phenotype.

218 further dissected, we need a precise genetic null mutant to definitively map its amorphic phenotypes.

219 horylation is indeed compromised in the H2Av null mutant, chromatin decondensation at heat shock loci

220 lar distribution of an overexpressed phospho-null mutant, TH1-S31A, was restricted to the soma of neu

221 5a-CD3 can rescue the phenotype of a pcdh15a-null mutant.

222 In line with this, Foxp2-null mutants also show a loss of ITCs at postnatal time

223 vpr-1 null mutants are maternal effect sterile due to arrested

224 dicate that many synaptic defects in unc-104-null mutants are mediated independently of Unc-104's tra

225 f zebrafish Pcdh15a (CD1 and CD3) in pcdh15a-null mutants by assessing Pcdh15a transgene-mediated res

226 n in intact parasites, we generated Deltaarg null mutants in L. donovani and evaluated their ability

227 Null mutants of bciD, which encodes a putative radical S

228 n patterns varied significantly between codY-null mutants of SM101 and CN3718.

229 alcium-mediated signalling, but abolished in null mutants of the pH-responsive transcription factor P

230 Drosophila CaMKII-null mutants remain viable throughout development, enabl

231 Generation of molecularly defined null mutants revealed that loss of 8 out of 13 JmjC gene

232 xplants and mouse embryonic fibroblasts from null mutants shows that the mesoderm migration defect is

233 Previously, imaA-null mutants were found to induce an elevated inflammato

234 eproduced the neonatal lethality observed in null mutants, indicating that the defective diaphragm is

235 ibed at robust levels in both H2Av and JIL-1 null mutants.

236 nses were monitored in two independent cerk1 null mutants; a deletion mutant lacking D14L, and with D

237 ll-derived neurons from a patient carrying a null mutation of the IL1RAPL1 gene had more dendrites.

238 ORAI1 null mutations are associated with reduced numbers of in

239 pper and its transporter ATP7A because ATP7A null mutations cause neurodegeneration.

240 We identified recessive null mutations in 8 additional probands, of which, 3 had

241 A recent study revealed that null mutations in ACC2, encoding a plastid-targeted acet

242 ISPR/Cas9 genome editing generated predicted null mutations in cnrip1a and cnrip1b.

243 pression rhythms are lost in the presence of null mutations in either cyc or the gene encoding the CL

244 Null mutations in filaggrin (FLG), a key epidermal barri

245 Biallelic null mutations in genes encoding interferon gamma recept

246 Cells that harbor null mutations in MELK exhibit wild-type doubling times,

247 r eukaryotic DNA replication, and homozygous null mutations of GINS component-encoding genes are embr

248 y untreated with FVIII concentrate, 197 with null mutations were classified as high risk and 38 with

249 were classified as high risk and 38 with non-null mutations were classified as low risk.

250 to 1.4 and confidence intervals spanning the null (n > 13990).

251 occurred in mPC with the emergence of an AR-null NE-null phenotype.

252 Otherwise, null networks based on basic knowledge about group size

253 ncluding action potential amplitude in Kcnq2-null neurons.

254 hat increased chemokine expression in FIP200-null NSCs was induced by abnormal p62 aggregate formatio

255 tential to inhibit differentiation of FIP200-null NSCs.

256 line competent and were used to produce DDX4 null offspring.

257 ALADIN null oocytes that mature far enough to be fertilized in

258 mice, on either the liver FA binding protein null or Apobec-1 null background (i.e., apolipoprotein B

259 t polar or charged substitutions resulted in null or cold-sensitive/small-plaque phenotypes.

260 indicated that 4 variants were functionally null or hypomorphic, while 1 was dominant negative.

261 lnerable intervention point in murine p53/Rb-null osteosarcomas, the human counterpart of which lacks

262 l defects and the impaired invasion of TgDCX-null parasites are corrected by reintroduction of a TgDC

263 e truncated GPI anchor side chains in TbRFT1 null parasites when compared with wild-type cells, a def

264 Female C57BL/6 mice (8 weeks old, null parity) vicariously experienced the defeat bout of

265 esponses were initially restricted to output-null patterns that cancelled out at the neural populatio

266 how that ME3 depletion selectively kills ME2-null PDAC cells in a manner consistent with an essential

267 on disrupted epicardium formation, and Cdc42 null PECs proliferated less, lost polarity and failed to

268 utation of C37 and C114 residues led to a gK-null phenotype characterized by very small plaque format

269 icularly efficacious against mPCs with an AR-null phenotype.

270 d in mPC with the emergence of an AR-null NE-null phenotype.

271 and were more sensitive to Mn toxicity than null plants.

272 Using DREAM-null platelets and PI3K isoform-specific inhibitors, we

273 FMRP-null PNs lose activity-dependent synaptic modulation, wi

274 , the thermodynamic model offers the correct null prediction for epistasis between mutations across D

275 ein 4.1 R isoform switching and protein 4.1R-null primitive erythroblasts fail to establish normal me

276 Introduction of PTEN into a PTEN null prostate cancer cell line leads to dephosphorylatio

277 R2) and BMP receptor II (BMPR2) using a Pten-null prostate cancer model.

278 eactive stromal microenvironment in the Pten null prostate cancer model.

279 sons in hypoxic and nonhypoxic areas produce null results, but we find strong evidence of the hypothe

280 l phenotype was found in the Dlx1/Dlx2/Brn3b-null retinas than was predicted by combining features of

281 rentiation marker MIST1 were altered in Irf6-null salivary gland and pancreas.

282 nificantly reduced seed vigor, compared with null segregant controls.

283 Here, we demonstrate that Suppressor of Mek null (Smek) interact with methyl-CpG-binding domain 3 (M

284 y calibrated (average chi(2) = 1.00-1.02 for null SNPs), whereas the Armitage trend test (ATT), stand

285 anism was facilitated by the circuit's large null space and its ability to strongly modulate output-p

286 Ejaculated CatSperz-null sperm cells retrieved from the mated female uterus

287 y interfacial residues as Hot-Spots (HS) and Null-Spots (NS).

288 Capzb-null stereocilia initially developed normally but later

289 ed the dramatic analgesia observed in Nav1.7-null subjects.

290 n regulating lipid output were higher in Pxr-null than in WT mice.

291 We conclude that HAQ is a null TMEM173 allele.

292 cell cycle arrest response, whereas, in p53-null transformed cells, the absence of arrest enables th

293 cin further increased uPA expression in TSC2-null tumor cells and immortalized TSC2-null angiomyolipo

294 ion and characterization of mice harboring a null Upf3b allele.

295 e of small magnitude and centered around the null value.

296 The null virus had greater proportions of empty (DNA-less) c

297 As was done for the HSV-2 study, a UL21-null virus was made and propagated on complementing cell

298 ivatives were examined in the context of the null virus, and all produced lytic rather than syncytial

299 Rs for barium and aluminum were close to the null, whereas associations with titanium, arsenic, and s

300 Although null Zfp423 mutants develop cerebellar malformations, th