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1 f factor IX is already a reality for a small number of patients.
2 ng remission of this refractory disease in a number of patients.
3 ill be key to meeting the needs of a growing number of patients.
4 ue of PET tracers with the smallest possible number of patients.
5 ilar pathogens were detected but in a larger number of patients.
6 estimating the treatment effect in a smaller number of patients.
7  renal-replacement therapy in an appreciable number of patients.
8 e a time lag and are ineffective for a large number of patients.
9 cterizing behavioral deficits across a large number of patients.
10 nhibition is being observed in an increasing number of patients.
11  genetic diagnosis is achieved for a greater number of patients.
12 ial approach was successful in a significant number of patients.
13 osis, cirrhosis, and cancer in a significant number of patients.
14  one of these alone would miss a significant number of patients.
15 sed in the future for the treatment of large numbers of patients.
16 pies to provide survival benefit for greater numbers of patients.
17 astic leukemia (ALL), often comprising small numbers of patients.
18 idely explored, but often only benefit small numbers of patients.
19 e following original research, cohort study, number of patients 10 or more, and reported change in ma
20                   In two small trials (total number of patients = 133), haloperidol did not appear to
21                                A substantial number of patients (38%) preferred alternative medicine
22 groupe Francophone du Myelome (IFM-G) (total number of patients: 4750).
23  to immunohistochemistry, identifies a small number of patients (5 cases) with high residual tumor bu
24 ated with high rates of side-effects and low numbers of patients achieving tolerance.
25                                 The adjusted number of patients, adjusted costs, quality, and efficie
26 ear study period (2012-2014), we tracked the number of patients affected by MDRPa (colonized and/or i
27  that uses both variation in performance and number of patients affected by the QM to set priorities
28 prevalence of NIU will help to determine the number of patients affected.
29 ssed the diagnostic cutoff of 0.8 in a small number of patients after valve replacement.
30 ide get more damaged in RA since the limited number of patients analyzed in the previous study had ma
31 nown as inhibitors, develop in a significant number of patients and actively block FVIII activity, ma
32 tterns of dissemination owing to the limited number of patients and available metastases.
33    Nevertheless, PSD occurs in a significant number of patients and constitutes an important complica
34                Further studies with a larger number of patients and longer follow-up are warranted.
35       Unfortunately, there are still a large number of patients and malignancies that do not respond
36                   We determined the absolute number of patients and the in-hospital death rate for cr
37                                          The number of patients and the number of eyes with MPGN-rela
38 care CRAG testing simplifies screening large numbers of patients and enables physicians to prioritize
39                                       Larger numbers of patients and longer follow-up are needed to c
40 t treatment can be detected in a substantial number of patients, and that this may be associated with
41                                A significant number of patients are at risk for DDIs if treated with
42                                A significant number of patients are hospitalized for the management o
43 sphagia from late-stage tumors; only a small number of patients are identified by screening and surve
44            Future studies with a much larger number of patients are needed to provide consistent safe
45 ith early-stage breast cancer, an increasing number of patients are pursuing mastectomy, which may be
46                                A significant number of patients are refractory to this treatment and
47 2 million deaths annually, and an increasing number of patients are resistant to existing therapies.
48                          Thus, a substantial number of patients are spared the adverse effects of sys
49 a number of recent audits suggest that large numbers of patients are failing to be assessed properly
50               In addition, today, increasing numbers of patients are found to have infection caused b
51                Controlled trials with larger numbers of patients are necessary to assess long-term ou
52                  The proportion of the total number of patients assigned to the intermediate-risk cat
53 e dental expertise and can be used for large numbers of patients attending obstetrics units.
54  are important for determining the potential number of patients available for cohort studies and anti
55                                  Significant number of patients avoided surgery or showed preference
56                                 However, the number of patients awaiting solid organ transplantation
57              The risk for PME is low and the number of patients benefiting from treatment is small.
58 million [13.2 million to 70.9 million]), the number of patients blind because of cataract is anticipa
59                     Furthermore, for a large number of patients, both TP53 alleles were altered, eith
60 ture trial designs could reduce the required number of patients by at least 20%.
61                 There was an increase in the number of patients cannulated per annum over the 10-year
62 repeat tests performed increased, as did the number of patient cases categorized as ISH equivocal.
63 ained reasonably complete data for a limited number of patient characteristics, namely age, sex, and
64 int was the difference between groups in the number of patients classified as treatment failure durin
65                       There are considerable numbers of patients coinfected with human immunodeficien
66                                          The number of patient conversions to hepatectomy was seven f
67 as the total number of events divided by the number of patient-days of follow-up in each interval ass
68                           Because of the low number of patients developing de novo DSA, the DSA resul
69  of mammographic screening will increase the number of patients diagnosed with DCIS, making a precise
70                                A substantial number of patients diagnosed with high-risk prostate can
71 y transplantation; however, a non-negligible number of patients did not benefit from transplantation
72                               A considerable number of patients discontinued glaucoma drug use altoge
73                       However, a significant number of patients do not respond (innate resistance), a
74            For unknown reasons a substantial number of patients do not show any improvement during or
75 tric hospitals to provide treatment to large numbers of patients during a large-scale disaster remain
76 e criteria, performance of the criteria, and number of patients eligible for organ donation.
77 ous observational study in terms of both the number of patients enrolled and the standardization of l
78 gression was used to study the effect of the number of patients enrolled at each institution on the m
79                                          The number of patients enrolled at each site varied between
80 equency of reporting adverse effects and the number of patients enrolled at each site.
81       Facilities were matched by type and by number of patients enrolled in HIV care.
82                                   The median number of patients enrolled in the pivotal trials was 66
83 f these factors, probably owing to the small number of patients enrolled in this study.
84 et patients, only a few reports with a small number of patients exist.
85           Among the different tests, similar numbers of patients experienced MACE after an abnormal t
86 dy treatment (17 [28%] vs 16 [26%]), and the number of patients experiencing severe adverse events (t
87 ielded favorable outcomes while limiting the number of patients exposed to toxic drugs.
88 ng could complicate retreatment of the small number of patients failing regimens containing an NS5A i
89                                          The numbers of patients, family members, and control subject
90 dia's private sector is treating an enormous number of patients for tuberculosis, appreciably higher
91                                          The number of patients for whom adverse events were reported
92 SA and Europe have substantially reduced the number of patients for whom antibiotic prophylaxis is re
93 vidence was generally of low quality and the numbers of patients for each drug were small.
94            Study limitations include a small number of patients from outpatient settings and LICs, po
95  recurrent ADs have been restricted to small numbers of patients from single institutions.
96 (BCVA) from baseline in the study eye and/or number of patients gaining at least 10 letters from base
97                                    A similar number of patients given haloperidol (12/34 [35%]) and p
98  procedural revascularization in significant numbers of patients has led to attempts to develop alter
99  virus (HIV) infection in Africa, increasing numbers of patients have pretreatment drug resistance.
100 ) have conflicting results, comprise a small number of patients, have short follow-up periods, and la
101                                An increasing number of patients having cancer surgery rely on PAC fac
102 sensitivity following SC challenge, over the number of patients having tested negative for both the S
103               At the 18-month follow-up, the numbers of patients hospitalized for any cause were simi
104                                          The number of patients identified as benefitting from therap
105                 The primary endpoint was the number of patients identified with significant coronary
106 HIV disease progression by analyzing a large number of patients in 3 cohorts with different HIV disea
107 ention by carotid artery stenting in a large number of patients in a real-world setting.
108       It is well accepted that a significant number of patients in a vegetative state are covertly aw
109 ng to surgical adjustments in a considerable number of patients in all malignancies studied but espec
110 epeat expansion exceeds that of the combined number of patients in all other microsatellite expansion
111 , even though it assumes a large and similar number of patients in both risk groups, which is violate
112 ), 107 patients were included, with the same number of patients in each clinical stage subgroup (12 s
113 l relevant data, including outcome, P value, number of patients in each group, number of events in ea
114  The availability of donor organs limits the number of patients in need who are offered liver transpl
115 re, we enrolled 334 RA patients, the biggest number of patients in studies to address this issue and
116 ed laboratories that may be unavailable to a number of patients in sub-Saharan Africa.
117 suggestive of IBD considerably decreased the number of patients in the group in whom challenges in cl
118                                          The number of patients in the postanesthesia care unit with
119 ts were not statistically significant as the number of patients in those groups was lower.
120 he random-effects model and weighted for the number of patients included in each trial.
121 have emerged because of the relatively small number of patients included in some stroke studies.
122                                        Total number of patients included in this study was 50.
123  limitations are the heterogeneity and small number of patients included in this study, the need for
124 le or in 2%-20% if calculated on the overall number of patients initially screened.
125 ssen or dissipate with time, study on larger numbers of patients is necessary to elucidate factors th
126  each group, number of events in each group, number of patients lost to follow-up, and trial characte
127 x, and type of rhythm disorder with an equal number of patients managed with uninterrupted vitamin K
128                                              Number of patients monitored in a simulation of cardiac
129 as to determine the impact of increasing the number of patients monitored on response time to simulat
130 AF and regular AT occurred in a considerable number of patients; most of them initially presented wit
131                   Based on data from a small number of patients (n = 6), an intensified 16-week regim
132 ex (E) was defined as a function of adjusted number of patients (N(a)), total practice adjusted costs
133 tratification could substantially reduce the number of patients necessary, when compared with no stra
134 eduction for MV with HFNC was 29.8%, and the number of patients needed to treat to prevent one intuba
135 s, preserve treatment effect, and reduce the number of patients needed.
136                             We estimated the number of patients needing RRT to be between 4.902 milli
137                The primary end point was the number of patients no longer requiring surgery at Week 2
138 sion development long term, regarding either number of patients (odds ratio 2.43; P = 0.03) or number
139                 Despite a recent fall in the number of patients on the transplant waiting list, there
140 vascular disease (CVD) were limited by small numbers of patients or a narrow range of endpoints.
141  derived mostly from studies with very small numbers of patients or in vitro data.
142                                   The median number of patients per study was 185 (interquartile rang
143                                    The large number of patients potentially affected represents an im
144                                          The number of patients potentially referred to MR imaging de
145  One was the perception that, given the high number of patients presenting simultaneously and the ver
146                                              Number of patients randomly assigned between groups, tri
147                               We tracked the number of patients readmitted after PCI to our hospital.
148 nderwent one of 12 major operations, and the number of patients readmitted or transferred back to the
149 ference between the randomised groups in the numbers of patients readmitted (100 [61%] of 165 CTOs vs
150 Antimicrobial use prevalence, defined as the number of patients receiving antimicrobial drugs at the
151 icans, which will significantly increase the number of patients recommended for outcome-related benef
152 egory 3 classification; however, the overall number of patients recommended for short-interval follow
153 different data domains (data diversity), the number of patient records in the training data set (data
154                                              Number of patients recruited, level of detected DR, chan
155 ucing promyelocyte maturation, a significant number of patients relapse due to the development of ATR
156 mias in adults and children, yet significant numbers of patients relapse and die of disease.
157 t present in clinical practice a significant number of patients remain unhealed.
158               There was no difference in the number of patients requesting a change in resuscitation
159 n in power, with a 67% mean reduction in the number of patients required in a drug trial for severe e
160                                          The number of patients requiring ambulatory chemotherapy is
161 rus infection have reduced mortality and the number of patients requiring liver transplantation, but
162 ing volatility indices measured from a small number of patient samples, we accurately predict the pop
163                                         Mean number of patients seen by APPs (260.7) was lower compar
164                            This included the number of patients seen within each clinic, operational
165                                An increasing number of patients show immediate selective hypersensiti
166 noids were associated with a greater average number of patients showing a complete nausea and vomitin
167                   There was no difference in number of patients showing improvement of >/=1 Canadian
168 ention the mean change in dystonia severity, number of patients studied, and evidence of efficacy bas
169                                          The number of patients suffering from allergic asthma and rh
170 nges in drug development because of the high number of patients suffering from neural diseases and th
171 h pioneering treatment trials based on small numbers of patients suggest progression-free and overall
172                                          The number of patients surviving with congenital heart disea
173 ain injury, ESA therapy did not increase the number of patients surviving with moderate disability or
174 delines or studies regarding the appropriate number of patients that a single watcher may safely and
175  guide antibiotic treatment and increase the number of patients that complete therapy.
176 y more than 50% without increasing the total number of patients to be screened.
177 ntroduction is safe and allows a significant number of patients to resume regular infusions.
178  among stage groups, upstaging a significant number of patients to stage IV.
179 ease necessitating the transfer of a growing number of patients to the adult healthcare service.
180                                          The number of patients transferred to an ICU was significant
181 has been slow, largely due to the very small number of patients treated and the heterogeneity of trea
182               We analyzed the effects of the number of patients treated by individual endoscopists an
183 ns or losses of patients (difference between number of patients treated in a centre and number expect
184 case' clinical benefit of new therapies, the number of patients treated was increased by a total of 1
185 dy to quantify the reduction in sample size, number of patients treated with the standard of care, an
186                                          The numbers of patients treated between sedation-related adv
187  from China, short onset-to-door time, lower numbers of patients treated per center, higher diastolic
188 ng to leave practice within 5 years, and the number of patients under their care.
189 50,116 procedures with a 55% increase in the number of patients undergoing pPCI at these facilities o
190 ome recognition and smaller decreases in the number of patients' visits to federally qualified health
191             For those days, we evaluated the number of patients waiting for ICU admission more than 4
192  At 3, 6, and 12 months after treatment, the number of patients was 40, 31, and 31, respectively, and
193                          The median adjusted number of patients was 5516 (interquartile range, 3450-1
194                                  The highest number of patients was in the age group of 51-60 years (
195 ons for benign lesions in a relatively small number of patients was responsible for positively skewed
196                  Although based on a limited number of patients, we conclude that a stricter psycholo
197                    In the study, the highest number of patients were found to have tongue malignancy
198 ved within some disease subsets as increased numbers of patients were identified, recruited, followed
199                  Similar outcomes in smaller numbers of patients were observed with apixaban (n = 12)
200  expression measurements on relatively small numbers of patients while also uncovering gene-gene rela
201                                          The number of patients who achieved a composite complete res
202     The primary objective was to compare the number of patients who achieved a pathological complete
203 device treatment to potentially increase the number of patients who can be treated despite long trans
204 iratory distress syndrome as an outcome, the number of patients who developed acute respiratory distr
205 risk (RR) was calculated on the basis of the number of patients who had been compulsorily admitted.
206                                          The number of patients who had mild, moderate, and severe VF
207 (3.8) versus 6.8 days (3.2; p=0.84), and the number of patients who had unscheduled hospital admissio
208 0.0-2.0] vs 1.0 [1.0-2.0]; P = .39), and the number of patients who missed at least 1 dose was also s
209    The primary objective was identifying the number of patients who present with sepsis and progress
210 ty with the revised versus the prior policy (number of patients who received increased priority for t
211    The authors have shown that a substantial number of patients who recovered sufficiently to allow e
212 f epilepsy surgery; this may help reduce the number of patients who refuse surgery after comprehensiv
213                                A significant number of patients who survive CO poisoning suffer from
214                                          The number of patients who underwent stenting ranged from 10
215                                          The number of patients who used antibiotics within 14 days w
216 formance (using interquartile range) and the number of patients who were affected; then the two ranki
217 proof-of-concept study is limited to a small number of patients who were selected based on several cr
218                       Explicitly stating the number of patients who will not benefit from the propose
219  progression of disease though a significant number of patients will be nonresponders.
220 versus most recent follow-up outcomes (i.e., number of patients with >/=1 GR and number of sites with
221 d, from 634 070 to 723 172 (+14.0%), and the number of patients with 1 or both eyes undergoing catara
222                           Owing to the small number of patients with 4-5 tumors, further investigatio
223                                          The number of patients with a family history suggestive of L
224                                    The total number of patients with a non-Val30Met mutation in the r
225                                          The number of patients with adult congenital heart disease (
226 afety-net hospitals treat a disproportionate number of patients with advanced appendicitis while fall
227                                          The number of patients with adverse events was similar in th
228 EER-Medicare data to create estimates of the number of patients with an HCV diagnosis, used an invers
229 ab plus gemcitabine and cisplatin group, the number of patients with at least one grade 3 or worse ad
230                    However, in a substantial number of patients with bipolar disorder, long-term lith
231                                       Median number of patients with cancer per center was 110 (inter
232 ion therapy is administered to a significant number of patients with cancer, and radiation reactions
233 at causes morbidity and mortality in a large number of patients with cancer.
234 immune tolerance can be useful for a growing number of patients with cancer.
235 inson's disease has been reported in a small number of patients with chromosome 22q11.2 deletion synd
236                                            A number of patients with chronic rhinosinusitis with nasa
237 get oncogenic WNT signaling in a significant number of patients with colorectal and other intestinal
238                        Particularly, a large number of patients with CRC also have liver metastasis.
239 d with the hepatitis C virus (HCV) ages, the number of patients with decompensated cirrhosis is expec
240 hort of normal healthy patients and an equal number of patients with different forms of anemia.
241 netic risk score could also identify a small number of patients with discrepant genetic risk profiles
242 xperience ischemic events, and a significant number of patients with dissection or aneurysm underwent
243 outcome-opioid oversupply-was defined as the number of patients with either filled but unused opioid
244                                Given the low number of patients with elevated NT-proBNP levels, this
245                                          The number of patients with end-stage renal disease being re
246     In conclusion, we demonstrate a relevant number of patients with FDG-PET false-negative MM and a
247                                            A number of patients with FHL and normal pigmentation rema
248                                      A small number of patients with germ cell cancer (GCC) receive m
249  patient adherence documented that a sizable number of patients with glaucoma do not take their medic
250 t months 6 to 12, there was no change in the number of patients with good versus poor outcomes.
251 selective beta-blocker therapy for the large number of patients with heart and respiratory or periphe
252                                          The number of patients with high intracranial pressure peake
253           To determine whether a significant number of patients with hyperparathyroidism remain undia
254 ean difference 1.31 [0.37 to 2.25]), and the number of patients with impaired glucose tolerance (odds
255        Despite these advances, a substantial number of patients with inflammatory arthritis remain re
256  CHD pretest likelihood, 49.5% [SD, 23.8%]), number of patients with invasive coronary angiography af
257 linical and genetic details of a substantial number of patients with IWC in order to define major and
258            The following data were recorded: number of patients with laBCC or mBCC, dose and frequenc
259 LG volumes in BPES, describing a significant number of patients with LG agenesis.
260 mechanisms of action to treat the increasing number of patients with life-threatening systemic fungal
261 nt regimes, however probably due to the high number of patients with liver cirrhosis and prior treatm
262                         The relatively small number of patients with LSDs and lack of validated bioma
263 ose To determine the association between the number of patients with multiple myeloma (MM) treated an
264                                          The number of patients with NETs and carcinoid syndrome incr
265  FKSI-DRS questionnaires completed using the number of patients with non-missing data at baseline and
266                                          The number of patients with nosocomial infections was signif
267                                          The number of patients with one or more serious adverse even
268 mance and prevent mobility loss in the large number of patients with PAD, including in those who are
269 in C5 cause eculizumab-resistance in a small number of patients with paroxysmal nocturnal hemoglobinu
270                                          The number of patients with persistent asthma in the nationa
271                                We calculated number of patients with pneumonia events, stratified by
272                       A significantly higher number of patients with PNTM than the other subjects had
273 ents with complications divided by the total number of patients with postoperative complications.
274                                            A number of patients with PSEN1 mutations had pyramidal (2
275                The primary end point was the number of patients with recurrent AP during the follow-u
276  outcomes were SpO2 after preoxygenation and number of patients with saturation less than 80%.
277  would permit transplantation to the highest number of patients with similar outcomes in recipients o
278                 Paradoxically, a significant number of patients with such variants suffer from febril
279  WT GIST permitted the evaluation of a large number of patients with this rare disease.
280 t-acting antivirals (DAAs), due to the small number of patients with treatment failure in approval st
281                                          The number of patients with treatment-associated complicatio
282                        India has the highest number of patients with tuberculosis and multidrug-resis
283 ssfully implemented in the greatest possible number of patients with type 1 diabetes.
284 highly dependent on weekday/weekend pattern, number of patients with various abnormal complete blood
285 tancy are the main reasons for an increasing number of patients with wound problems.
286              Our findings confirm that large numbers of patients with a representative variety of CMT
287  from the electronic health records of large numbers of patients with cancer.
288 care systems will need to accommodate rising numbers of patients with cirrhosis and HCC.
289 ithout patient navigation, in increasing the numbers of patients with cirrhosis undergoing surveillan
290 ology community is increasingly facing small numbers of patients with each cancer subtype, requiring
291                                        Large numbers of patients with end-stage kidney disease caused
292       Thereafter, KGH received and cared for numbers of patients with EVD that quickly overwhelmed th
293 ilable for clinical evaluation; however, the numbers of patients with FL and the resources to conduct
294  the majority of studies were based on small numbers of patients with graft failure.
295 pre-treatment loss to follow-up) between the numbers of patients with laboratory-confirmed RR-TB and
296                                   Increasing numbers of patients with prolonged mechanical ventilatio
297 and should be determined, because increasing numbers of patients with SCD take this drug to improve r
298 use of unrelated donors has led to increased numbers of patients with this painful complication.
299                  To address implications for numbers of patients with tuberculosis, we explored varyi
300 tive care facilities are scarce, substantial numbers of patients with XDR tuberculosis who have faile

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