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1 f factor IX is already a reality for a small number of patients.
2 ng remission of this refractory disease in a number of patients.
3 ill be key to meeting the needs of a growing number of patients.
4 ue of PET tracers with the smallest possible number of patients.
5 ilar pathogens were detected but in a larger number of patients.
6 estimating the treatment effect in a smaller number of patients.
7 renal-replacement therapy in an appreciable number of patients.
8 e a time lag and are ineffective for a large number of patients.
9 cterizing behavioral deficits across a large number of patients.
10 nhibition is being observed in an increasing number of patients.
11 genetic diagnosis is achieved for a greater number of patients.
12 ial approach was successful in a significant number of patients.
13 osis, cirrhosis, and cancer in a significant number of patients.
14 one of these alone would miss a significant number of patients.
15 sed in the future for the treatment of large numbers of patients.
16 pies to provide survival benefit for greater numbers of patients.
17 astic leukemia (ALL), often comprising small numbers of patients.
18 idely explored, but often only benefit small numbers of patients.
19 e following original research, cohort study, number of patients 10 or more, and reported change in ma
23 to immunohistochemistry, identifies a small number of patients (5 cases) with high residual tumor bu
26 ear study period (2012-2014), we tracked the number of patients affected by MDRPa (colonized and/or i
27 that uses both variation in performance and number of patients affected by the QM to set priorities
30 ide get more damaged in RA since the limited number of patients analyzed in the previous study had ma
31 nown as inhibitors, develop in a significant number of patients and actively block FVIII activity, ma
33 Nevertheless, PSD occurs in a significant number of patients and constitutes an important complica
38 care CRAG testing simplifies screening large numbers of patients and enables physicians to prioritize
40 t treatment can be detected in a substantial number of patients, and that this may be associated with
43 sphagia from late-stage tumors; only a small number of patients are identified by screening and surve
45 ith early-stage breast cancer, an increasing number of patients are pursuing mastectomy, which may be
47 2 million deaths annually, and an increasing number of patients are resistant to existing therapies.
49 a number of recent audits suggest that large numbers of patients are failing to be assessed properly
54 are important for determining the potential number of patients available for cohort studies and anti
58 million [13.2 million to 70.9 million]), the number of patients blind because of cataract is anticipa
62 repeat tests performed increased, as did the number of patient cases categorized as ISH equivocal.
63 ained reasonably complete data for a limited number of patient characteristics, namely age, sex, and
64 int was the difference between groups in the number of patients classified as treatment failure durin
67 as the total number of events divided by the number of patient-days of follow-up in each interval ass
69 of mammographic screening will increase the number of patients diagnosed with DCIS, making a precise
71 y transplantation; however, a non-negligible number of patients did not benefit from transplantation
75 tric hospitals to provide treatment to large numbers of patients during a large-scale disaster remain
77 ous observational study in terms of both the number of patients enrolled and the standardization of l
78 gression was used to study the effect of the number of patients enrolled at each institution on the m
86 dy treatment (17 [28%] vs 16 [26%]), and the number of patients experiencing severe adverse events (t
88 ng could complicate retreatment of the small number of patients failing regimens containing an NS5A i
90 dia's private sector is treating an enormous number of patients for tuberculosis, appreciably higher
92 SA and Europe have substantially reduced the number of patients for whom antibiotic prophylaxis is re
96 (BCVA) from baseline in the study eye and/or number of patients gaining at least 10 letters from base
98 procedural revascularization in significant numbers of patients has led to attempts to develop alter
99 virus (HIV) infection in Africa, increasing numbers of patients have pretreatment drug resistance.
100 ) have conflicting results, comprise a small number of patients, have short follow-up periods, and la
102 sensitivity following SC challenge, over the number of patients having tested negative for both the S
106 HIV disease progression by analyzing a large number of patients in 3 cohorts with different HIV disea
109 ng to surgical adjustments in a considerable number of patients in all malignancies studied but espec
110 epeat expansion exceeds that of the combined number of patients in all other microsatellite expansion
111 , even though it assumes a large and similar number of patients in both risk groups, which is violate
112 ), 107 patients were included, with the same number of patients in each clinical stage subgroup (12 s
113 l relevant data, including outcome, P value, number of patients in each group, number of events in ea
114 The availability of donor organs limits the number of patients in need who are offered liver transpl
115 re, we enrolled 334 RA patients, the biggest number of patients in studies to address this issue and
117 suggestive of IBD considerably decreased the number of patients in the group in whom challenges in cl
121 have emerged because of the relatively small number of patients included in some stroke studies.
123 limitations are the heterogeneity and small number of patients included in this study, the need for
125 ssen or dissipate with time, study on larger numbers of patients is necessary to elucidate factors th
126 each group, number of events in each group, number of patients lost to follow-up, and trial characte
127 x, and type of rhythm disorder with an equal number of patients managed with uninterrupted vitamin K
129 as to determine the impact of increasing the number of patients monitored on response time to simulat
130 AF and regular AT occurred in a considerable number of patients; most of them initially presented wit
132 ex (E) was defined as a function of adjusted number of patients (N(a)), total practice adjusted costs
133 tratification could substantially reduce the number of patients necessary, when compared with no stra
134 eduction for MV with HFNC was 29.8%, and the number of patients needed to treat to prevent one intuba
138 sion development long term, regarding either number of patients (odds ratio 2.43; P = 0.03) or number
140 vascular disease (CVD) were limited by small numbers of patients or a narrow range of endpoints.
145 One was the perception that, given the high number of patients presenting simultaneously and the ver
148 nderwent one of 12 major operations, and the number of patients readmitted or transferred back to the
149 ference between the randomised groups in the numbers of patients readmitted (100 [61%] of 165 CTOs vs
150 Antimicrobial use prevalence, defined as the number of patients receiving antimicrobial drugs at the
151 icans, which will significantly increase the number of patients recommended for outcome-related benef
152 egory 3 classification; however, the overall number of patients recommended for short-interval follow
153 different data domains (data diversity), the number of patient records in the training data set (data
155 ucing promyelocyte maturation, a significant number of patients relapse due to the development of ATR
159 n in power, with a 67% mean reduction in the number of patients required in a drug trial for severe e
161 rus infection have reduced mortality and the number of patients requiring liver transplantation, but
162 ing volatility indices measured from a small number of patient samples, we accurately predict the pop
166 noids were associated with a greater average number of patients showing a complete nausea and vomitin
168 ention the mean change in dystonia severity, number of patients studied, and evidence of efficacy bas
170 nges in drug development because of the high number of patients suffering from neural diseases and th
171 h pioneering treatment trials based on small numbers of patients suggest progression-free and overall
173 ain injury, ESA therapy did not increase the number of patients surviving with moderate disability or
174 delines or studies regarding the appropriate number of patients that a single watcher may safely and
179 ease necessitating the transfer of a growing number of patients to the adult healthcare service.
181 has been slow, largely due to the very small number of patients treated and the heterogeneity of trea
183 ns or losses of patients (difference between number of patients treated in a centre and number expect
184 case' clinical benefit of new therapies, the number of patients treated was increased by a total of 1
185 dy to quantify the reduction in sample size, number of patients treated with the standard of care, an
187 from China, short onset-to-door time, lower numbers of patients treated per center, higher diastolic
189 50,116 procedures with a 55% increase in the number of patients undergoing pPCI at these facilities o
190 ome recognition and smaller decreases in the number of patients' visits to federally qualified health
192 At 3, 6, and 12 months after treatment, the number of patients was 40, 31, and 31, respectively, and
195 ons for benign lesions in a relatively small number of patients was responsible for positively skewed
198 ved within some disease subsets as increased numbers of patients were identified, recruited, followed
200 expression measurements on relatively small numbers of patients while also uncovering gene-gene rela
202 The primary objective was to compare the number of patients who achieved a pathological complete
203 device treatment to potentially increase the number of patients who can be treated despite long trans
204 iratory distress syndrome as an outcome, the number of patients who developed acute respiratory distr
205 risk (RR) was calculated on the basis of the number of patients who had been compulsorily admitted.
207 (3.8) versus 6.8 days (3.2; p=0.84), and the number of patients who had unscheduled hospital admissio
208 0.0-2.0] vs 1.0 [1.0-2.0]; P = .39), and the number of patients who missed at least 1 dose was also s
209 The primary objective was identifying the number of patients who present with sepsis and progress
210 ty with the revised versus the prior policy (number of patients who received increased priority for t
211 The authors have shown that a substantial number of patients who recovered sufficiently to allow e
212 f epilepsy surgery; this may help reduce the number of patients who refuse surgery after comprehensiv
216 formance (using interquartile range) and the number of patients who were affected; then the two ranki
217 proof-of-concept study is limited to a small number of patients who were selected based on several cr
220 versus most recent follow-up outcomes (i.e., number of patients with >/=1 GR and number of sites with
221 d, from 634 070 to 723 172 (+14.0%), and the number of patients with 1 or both eyes undergoing catara
226 afety-net hospitals treat a disproportionate number of patients with advanced appendicitis while fall
228 EER-Medicare data to create estimates of the number of patients with an HCV diagnosis, used an invers
229 ab plus gemcitabine and cisplatin group, the number of patients with at least one grade 3 or worse ad
232 ion therapy is administered to a significant number of patients with cancer, and radiation reactions
235 inson's disease has been reported in a small number of patients with chromosome 22q11.2 deletion synd
237 get oncogenic WNT signaling in a significant number of patients with colorectal and other intestinal
239 d with the hepatitis C virus (HCV) ages, the number of patients with decompensated cirrhosis is expec
241 netic risk score could also identify a small number of patients with discrepant genetic risk profiles
242 xperience ischemic events, and a significant number of patients with dissection or aneurysm underwent
243 outcome-opioid oversupply-was defined as the number of patients with either filled but unused opioid
246 In conclusion, we demonstrate a relevant number of patients with FDG-PET false-negative MM and a
249 patient adherence documented that a sizable number of patients with glaucoma do not take their medic
251 selective beta-blocker therapy for the large number of patients with heart and respiratory or periphe
254 ean difference 1.31 [0.37 to 2.25]), and the number of patients with impaired glucose tolerance (odds
256 CHD pretest likelihood, 49.5% [SD, 23.8%]), number of patients with invasive coronary angiography af
257 linical and genetic details of a substantial number of patients with IWC in order to define major and
260 mechanisms of action to treat the increasing number of patients with life-threatening systemic fungal
261 nt regimes, however probably due to the high number of patients with liver cirrhosis and prior treatm
263 ose To determine the association between the number of patients with multiple myeloma (MM) treated an
265 FKSI-DRS questionnaires completed using the number of patients with non-missing data at baseline and
268 mance and prevent mobility loss in the large number of patients with PAD, including in those who are
269 in C5 cause eculizumab-resistance in a small number of patients with paroxysmal nocturnal hemoglobinu
273 ents with complications divided by the total number of patients with postoperative complications.
277 would permit transplantation to the highest number of patients with similar outcomes in recipients o
280 t-acting antivirals (DAAs), due to the small number of patients with treatment failure in approval st
284 highly dependent on weekday/weekend pattern, number of patients with various abnormal complete blood
289 ithout patient navigation, in increasing the numbers of patients with cirrhosis undergoing surveillan
290 ology community is increasingly facing small numbers of patients with each cancer subtype, requiring
293 ilable for clinical evaluation; however, the numbers of patients with FL and the resources to conduct
295 pre-treatment loss to follow-up) between the numbers of patients with laboratory-confirmed RR-TB and
297 and should be determined, because increasing numbers of patients with SCD take this drug to improve r
298 use of unrelated donors has led to increased numbers of patients with this painful complication.
300 tive care facilities are scarce, substantial numbers of patients with XDR tuberculosis who have faile
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