ライフサイエンスコーパス: numerous

1 Species with numerous actin genes are especially useful for the disse

2 highly conserved primary activity; however, numerous additional activities have been attributed to t

3 on fundamental systematic research, yielding numerous, additional, well-sampled phylogenies of TRF li

4 eatment of neurodegenerative diseases, given numerous advancements made to their chemical modificatio

5 ortable and autonomous device operation with numerous advantages as compared to electronics built fro

6 The sensor possesses numerous advantages like fast response time (<15s), simp

7 The oral microbiome has numerous advantages that make it particularly useful for

8 Labeling of PSMA tracers with (18)F offers numerous advantages, including improved image resolution

9 ut it later spread worldwide, accounting for numerous AHC outbreaks and two pandemics.

10 Since 1988, numerous allergen immunotherapy guidelines (AIT-GLs) hav

11 The evolution of the IgE response to the numerous allergen molecules of Dermatophagoides pteronys

12 osis-infected lymphatic tissues, we revealed numerous alterations of host transcripts associated with

13 MBP exhibits extreme microheterogeneity with numerous alternative splice variants (ASVs) and post-tra

14 ion is strongly favored over N-oxidation for numerous amine derivatives.

15 The identification of numerous AMPK targets has helped explain how AMPK restor

16 idence suggesting that such interactions are numerous and that a successful therapy against a particu

17 the vicinity of methane form stronger, more numerous, and more tetrahedrally oriented hydrogen bonds

18 Numerous animal and cellular models have now demonstrate

19 t reefs are degrading rapidly in response to numerous anthropogenic drivers.

20 Fe-4S] clusters and their incorporation into numerous apoproteins.

21 potential to replace persistent polymers in numerous applications and to thereby reduce the accumula

22 ow-cost fabrication of actuation systems for numerous applications at multiple scales, ranging from m

23 phiphilic block copolymers (ABCs) have found numerous applications in pharmaceutical, electronics, en

24 (sel)-SHARPER sequences are expected to find numerous applications in the design of new NMR experimen

25 ative to their gold and silver analogues for numerous applications, although their potential has hard

26 enes, have displayed promising properties in numerous applications, such as energy storage, electroma

27 ss to 2-enoic acids allows derivatization by numerous approaches.

28 ral DNA nanotechnology finds applications in numerous areas, but the construction of objects, 2D and

29 Dopamine (DA) transmission mediates numerous aspects of behavior.

30 The gut microbiota is implicated in numerous aspects of health and disease, but dissecting t

31 tinal tract (i.e., the microbiota) influence numerous aspects of host physiology.

32 Whereas numerous asymmetric methods for formation of quaternary

33 ome (BCNS) have a greater risk of developing numerous basal cell carcinomas (BCCs).

34 tis elegans, dietary restriction (DR) grants numerous benefits, including enhanced learning.

35 sistance in gram-negative bacteria (GNB) are numerous; beta-lactamase genes carried on mobile genetic

36 r of secondary metabolism and a repressor of numerous BGCs.

37 s and glycoconjugates are widely involved in numerous biological functions.

38 Ras proteins play vital roles in numerous biological processes and Ras mutations are foun

39 cNAcylation of target proteins and regulates numerous biological processes.

40 a-N-acetylglucosamine (GlcNAc) and regulates numerous biological processes.

41 modulators of gene expression that fine-tune numerous biological processes.

42 , ME-SIMS has proven useful for detection of numerous biorelevant species, now including peptides.

43 t-sensitive-that is, capable of interpreting numerous brain states, presented in arbitrary combinatio

44 l course, diffuse thickening of the walls of numerous bronchial branches and a "ground glass" opacity

45 Numerous calcium sources are available to enrich food, b

46 e successfully predicted patient outcomes in numerous cancer sites.

47 impact of Pin1 overexpression on activating numerous cancer-driving pathways including global miRNA

48 1 is overexpressed in most HCC and activates numerous cancer-driving pathways.

49 horts revealed six associated loci harboring numerous candidate genes, including EDAR, SP5, MRPS22, A

50 Given that optimism was associated with numerous causes of mortality, it may provide a valuable

51 f the human proteome play important roles in numerous cellular functions.

52 ar actin dynamics is an essential element of numerous cellular processes, such as cell motility, cell

53 l modifications of histone proteins regulate numerous cellular processes.

54 -like modifier (SUMO) modification regulates numerous cellular processes.

55 and its paralog p300 play a critical role in numerous cellular processes.

56 mmonly collected disease data is hampered by numerous challenges, including short-term surveillance t

57 in turn, associates with the development of numerous chronic diseases.

58 f myeloid-dendritic cell receptor DC-SIGN by numerous chronic infectious agents, including Porphyromo

59 Considering that numerous ciliary genes are associated with a scoliosis p

60 Numerous classes of natural products have been subjected

61 s essential for maintaining the stability of numerous client proteins.

62 dicine; these devices have been the topic of numerous clinical and economic evaluations during the pa

63 lations, but hold great promise for treating numerous CNS disorders.

64 clear evidence of genotoxicity, indicated by numerous common integration sites near proto-oncogenes a

65 hose from other classes of vertebrates shows numerous common traits shared by most groups and also hi

66 Although numerous compounds have been developed and widely used t

67 becoming a powerful analgesic treatment for numerous conditions, including osteoarthritis and lower

68 -on-chronic liver failure is associated with numerous consecutive organ failures and a high short-ter

69 Climatic modification of LSWT has numerous consequences for water quality and lake ecosyst

70 In particular, those possessing numerous contiguous, fully substituted carbon atoms (i.e

71 iodinium symbiosis, and possibly some of the numerous coral diseases that have yet to be assigned a c

72 r 2 (FGFR2) kinase, is still unknown, as the numerous crystal structures of the unphosphorylated and

73 disorder of unknown cause, characterized by numerous cutaneous and internal venous malformations; ga

74 audins and ZO-1/2/3 and between ZO-1/2/3 and numerous cytoskeletal proteins has been demonstrated in

75 pulation of multipotent stem cells that form numerous defining features of vertebrates.

76 With three biosimilars already licensed and numerous development programs under way, clinicians can

77 Although there are numerous devices developed to isolate individual circula

78 Numerous dietary restrictions and endoscopies limit the

79 Despite numerous differences between the elk populations in this

80 The numerous differences between the pathogenic and nonpatho

81 y other industrially-relevant chemicals from numerous different carbon sources.

82 Normal kidney function involves numerous different cell types, such as tubular epithelia

83 Genome-wide association studies identified numerous disease risk loci.

84 plays a prominent pathophysiological role in numerous diseases and pathophysiological conditions with

85 that breastfeeding reduces the prevalence of numerous diseases compared to mothers that give birth bu

86 SNARE mutations have been associated with numerous diseases, especially neurological disorders.

87 nserved cell stress response associated with numerous diseases, including cardiac hypertrophy and hea

88 en shown to be associated with phenotypes of numerous diseases, including malaria.

89 to applied biocatalysis is motivated by its numerous economic and environmental benefits.

90 e for Huntington's disease (HD) has promoted numerous efforts to uncover cellular pathways that lower

91 on technology has enabled the development of numerous electron optic elements for enhancing image con

92 CSDS affected numerous endpoints, including paradoxical sleep (PS) and

93 3 loop; here, we determined, via mutation of numerous Env residues, which of these elements maintain

94 This approach may be amenable to numerous enzymes and to engineering and screening approa

95 responses to stress and the biosynthesis of numerous essential compounds.

96 s) represent the single largest component of numerous eukaryotic genomes, and their activity and disp

97 on-avian dinosaurs to birds that has created numerous evolutionary innovations such as self-powered f

98 y acquire CMV infection, it usually requires numerous exposures.

99 n involved in the maintenance and control of numerous facets of plant physiology and development.

100 fferences evident between populations, where numerous factors (environmental variation, genomic backg

101 Population-based studies have identified numerous factors that modify the atrial substrate and in

102 cient genome duplication, cells have evolved numerous factors that promote unperturbed DNA replicatio

103 Amphibian declines have been linked to numerous factors, including pesticide use and the fungal

104 Numerous findings in murine models suggest a predominant

105 mplex architecture that is often composed of numerous functional motifs.

106 Despite the numerous functions executed by granulosa cells (GCs) in

107 r chains, which will be key to investigating numerous fundamental issues that thus far have remained

108 ociated with extracardiac organ dysfunction, numerous gaps in our understanding of the nature of this

109 The enteric nervous system (ENS) regulates numerous gastrointestinal functions, including epithelia

110 ity of lncRNAs to regulate the expression of numerous genes distributed across the genome.

111 lly unmyelinated axons and the expression of numerous genes encoding regulatory proteins.

112 tome analysis shows diminished RNA levels of numerous genes in Nfatc1 (-/-) CD8(+) T cells, including

113 OD1, leads to up-regulation of expression of numerous genes modulating fatty acid metabolism, includi

114 degenerative motor neuron disease linked to numerous genetic mutations in apparently unrelated prote

115 tive chromatin biology because sequencing of numerous genomes from many clades is coupled to existing

116 Numerous Gram-negative pathogens infect eukaryotes and u

117 ection by the Epstein-Barr virus (EBV) poses numerous health risks, such as infectious mononucleosis

118 irus type 1 (HSV-1) reproduction relies upon numerous host energy-intensive processes, the most deman

119 mRNA expression signature that is present in numerous human cancers and is associated with poor survi

120 ave roles in myriad biological processes and numerous human diseases.

121 e in cell cycle progression, is activated in numerous human malignancies, and is linked to chromosome

122 Dysregulation of this mechanism leads to numerous human neurodegenerative or neurodevelopmental d

123 Ixodes scapularis ticks harbor numerous human pathogens, including Anaplasma phagocytop

124 Numerous human polyTE loci correspond to both cis and tr

125 nd the results contrast with the findings of numerous human studies that find a PAC effect, as well a

126 gamma may be important in the development of numerous IL-36gamma-driven pathologies, in addition to p

127 stic and systemic levels in Escherichia coli Numerous important insights on DNA repair were obtained,

128 Total Nkx2.1(+) progenitors were also more numerous in the LGEs of preterm pups at D3 compared with

129 s) revealed reduced population-wide fitness, numerous individual variants were found to have activity

130 quilibria of fluid mixtures are important in numerous industrial applications and are, thus, a major

131 onstitutes a central event in the context of numerous infectious and sterile inflammatory conditions.

132 Although FetA is involved in numerous inflammatory conditions, its potential role in

133 control T cell-mediated immune responses in numerous inflammatory diseases.

134 in human PBMCs attenuated the expression of numerous inflammatory mediators implicated in the TSS-as

135 While the responses were highly variable, numerous instances of cross-reactive killing were observ

136 bining site is achieved via the formation of numerous interactions with heavy chain complementarity d

137 er, such organelles are multicomponent, with numerous intermolecular interactions that can potentiall

138 rovide an objective evidence base to support numerous international policy initiatives to reform lega

139 ellular bacteria that infect the germline of numerous invertebrate species worldwide.

140 Over the last decade, numerous investigations have attempted to clarify the in

141 , e.g. HNSO and HSNO, have been the focus of numerous investigations in recent years in view of their

142 Such potential has spurred numerous investigations yielding both promising and conf

143 Nearly all compounds comprise numerous isotopologues ensuing from stable natural isoto

144 eath, and transcriptomic analysis identified numerous key signaling pathways that were differentially

145 NAs, one of which may trigger phasiRNAs from numerous kinase transcripts.

146 Numerous Kv1.1 mutations have been associated with the h

147 NA methylome of skeletal muscle demonstrates numerous local methylation differences between LOS and c

148 From December 2014 to June 2016, numerous localized changes were observed, which we attri

149 cells (HBEC) is essential for understanding numerous lung diseases.

150 ) are positive-sense RNA viruses that infect numerous mammalian and avian species and are capable of

151 h cleft lip and/or palate (CLP), who undergo numerous medical interventions from infancy, can suffer

152 Imaging revealed numerous metastases in the lungs, liver, and brain.

153 Since there exist numerous methods and techniques for scaffold assembly, i

154 To solve this problem, numerous methods of countermeasure have been proposed.

155 iation, high chromosome numbers, presence of numerous microchromosomes and propensity to interspecifi

156 tunately, diagnosis can be difficult, due to numerous mimics, and to the absence of a specific test.

157 e structures, three intermediate states, and numerous misfolded states, the latter of which have not

158 Numerous models explore how a wide variety of biological

159 Despite the extensive description of numerous molecular changes associated with aging, insigh

160 occurring foodborne pathogen responsible for numerous multistate outbreaks in the United States.

161 Numerous mutations have been identified in the MyTH4-FER

162 Relapsed patients also developed numerous mutations targeting key breast cancer-associate

163 of Tet2(-/-) tumours reveals accumulation of numerous mutations, including Apc, Nf1, Flt3, Cbl, Notch

164 Numerous nanometrology techniques have been developed in

165 s, which form the key structural moieties of numerous natural biologically active compounds.

166 Despite the identification of numerous NDMA precursors, essential parts of the reactio

167 pathway are discussed.SIGNIFICANCE STATEMENT Numerous Neuregulins (NRGs) are generated through the us

168 Brain atrophy is a common feature of numerous neurologic diseases in which the role of neuroi

169 s and axonal ER dysfunction is implicated in numerous neurological diseases, its role at nerve termin

170 PA receptor-mediated signalling is linked to numerous neurological diseases.

171 loid types and have led to identification of numerous new amyloid types, including ALECT2 amyloidosis

172 Numerous newly detected intermediates-many separated by

173 perspective, allowing the identification of numerous noncoding RNAs with key roles in biological pro

174 The Mexican oaks are particularly numerous, not because Mexico is a center of origin, but

175 omic study resulted in the identification of numerous novel sequences.

176 However, numerous novel types of bacteria that were initially enr

177 an essential human enzyme that glycosylates numerous nuclear and cytoplasmic proteins on serine and

178 ted gene 1 (NDRG1) has been shown to inhibit numerous oncogenic signaling pathways in cancer cells.

179 nment and the structural integrity, offering numerous opportunities for biosensing applications.

180 This work not only identifies numerous opportunities for enhanced lymphoid-specific co

181 Astaxanthin is a carotenoid pigment found in numerous organisms ranging from bacteria to algae, yeast

182 ork principles underlying motor behaviors in numerous organisms, including humans.

183 Yet, the complementary reactivity of gold to numerous other transition metals would offer new synthet

184 the inner and outer NPC rings, but it lacks numerous others including cytoplasmically and nucleoplas

185 ins that augment ER protein folding, induced numerous oxidative stress response genes not previously

186 of phosphoglycerate isomers is catalysed in numerous pathogenic microorganisms by a cofactor-indepen

187 transporter plays a role in defense against numerous pathogens and is recruited to sites of pathogen

188 and perhaps other infectious RNAs.IMPORTANCE Numerous pathogens, including viruses, express pathogeni

189 hil recruitment as each phagocyte eliminated numerous pathogens.

190 D)-the electrophysiological event underlying numerous pathologies including migraine, ischemic stroke

191 s a drug target of considerable interest for numerous pathologies.

192 sed axonal transport is tightly regulated by numerous pathways, ensuring appropriate delivery of spec

193 -hydroxyecdysone (20E) in the maintenance of numerous patterning systems in vivo and in explant cultu

194 Numerous peripheral proteins, including several that wer

195 As a countermeasure, numerous phages are known that produce proteins to block

196 Numerous phosphoproteins involved in actin dynamics incl

197 In numerous physical models on networks, dynamics are based

198 Numerous physical processes have been proposed to accoun

199 Hydrophobicity plays an important role in numerous physicochemical processes from the process of d

200 Auxin steers numerous physiological processes in plants, making the t

201 easingly appreciated as active regulators of numerous physiological processes initially considered ex

202 l component of caveolae and is implicated in numerous physiological processes.

203 identified in two children with diarrhea and numerous pigs in Taiwan.

204 es have been identified and characterized in numerous plant pathosystems.

205 CAs are expressed in numerous plant tissues and in different cellular locatio

206 Numerous population-based studies have documented high p

207 earrangements for each selected class of the numerous porphyrinoids accordingly categorized by the nu

208 of differentially regulated genes highlights numerous potential targets for the design of novel thera

209 nts of the 3' untranslated region (3'UTR) of numerous pro-inflammatory cytokines including IL-4, IL-1

210 the surface chemistry and photochemistry of numerous probe molecules on various surfaces exposed by

211 It is possible that the numerous proteins encoded by these mycobacterial genes d

212 The HSV-1 genome encodes numerous proteins that are dedicated to combat host anti

213 Toxoplasma secretes numerous proteins to modify the forming vacuole, enable

214 ess, results in increased O-GlcNAcylation of numerous proteins, and this increase is thought to promo

215 Numerous publications have addressed CD147 as a tumor ma

216 Numerous publications have suggested that RNAs (microRNA

217 eum possessed significantly higher levels of numerous pyrrolizidine alkaloids involved in plant defen

218 eorites therefore hold the key to addressing numerous questions about our solar system.

219 Numerous recent scientific publications investigating th

220 Numerous regional studies have demonstrated phytoplankto

221 boratory contexts are best constructed after numerous repetitions of the very same stimulus in the ab

222 There are numerous reports in the literature that mimic the sample

223 They are now regularly synthesized in numerous research laboratories worldwide with diverse sp

224 these databases to attract the attention of numerous researchers working in various areas of genetic

225 ave become increasingly common worldwide and numerous retrospective studies have indicated that ART-c

226 Numerous review characteristics were evaluated, includin

227 II amacrine cells avoid making synapses with numerous RGC types that co-stratify with the connected R

228 Numerous ribosomal proteins were identified, confirming

229 e ordered assembly of ribosomal proteins and numerous RNA structural rearrangements.

230 Numerous RNAs are enriched within cellular protrusions,

231 wed a consistent pathological signature with numerous round, hyaline, TAR DNA-binding protein 43 (TDP

232 odel fungus Aspergillus nidulans synthesizes numerous secondary metabolites, including sterigmatocyst

233 hological development and ability to produce numerous secondary metabolites.

234 By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in

235 sediments of the Gulf of Mexico, leading to numerous seeps at the seafloor, where complex microbial,

236 ree months, spanning the duration over which numerous sensory and neuromuscular phenotypes manifest.

237 It then performs numerous sequence simulations under randomly sampled ind

238 functional genomics of different species in numerous settings.

239 We identified numerous shared and unique biases among these regions.

240 responsiveness to dobutamine is limited with numerous side effects.

241 tors which have been shown to be involved in numerous signaling pathways in Arabidopsis.

242 Numerous simulation studies have investigated these inte

243 ng specificities likely accommodate the more numerous sites of insertion versus deletion editing as e

244 d to study the composition and effect of the numerous slightly deleterious variants in humans and mod

245 Whereas numerous small-molecule positive allosteric modulators o

246 Numerous solutions have been proposed to boost food prod

247 The numerous species that make up the oral microbiome are no

248 The enrichment of numerous splicing factors like hnRNP proteins before ZGA

249 f public CLIP-seq/RIP-seq datasets involving numerous splicing factors, microRNAs and m6A RNA methyla

250 ly available V. cholerae genomes showed that numerous strains possess long arrays of orphan immunity

251 Numerous strategies to improve drug distribution have be

252 Viruses have evolved numerous strategies to specifically interfere with IFN p

253 part because it has the ability to withstand numerous stresses imposed by host immunity.

254 rconverting molecules that play key roles in numerous structural and signaling processes.

255 itical review of existing literature yielded numerous studies claiming transgenerational impacts, wit

256 While numerous studies have addressed causes and consequences

257 Over the past several years, numerous studies have been performed to synthesize and e

258 description of atrial fibrillation ablation, numerous studies have demonstrated the superiority of ca

259 Numerous studies have examined the prevalence of pathoge

260 Although numerous studies have focused on pentameric ligand-gated

261 Over the past several decades, numerous studies have greatly expanded our knowledge abo

262 Although numerous studies have identified networks of interacting

263 In particular, numerous studies have implicated the prefrontal cortex i

264 Numerous studies have indicated that aberrant splicing p

265 Although numerous studies have observed a role for the minus-end

266 Numerous studies have observed that, during working memo

267 Numerous studies have reported sex bias in infectious di

268 Numerous studies have shown that D-dimer serves as a val

269 Numerous studies have shown that p53beta/gamma can modul

270 Numerous studies have shown that proteolysis and oxidati

271 in hybrids, graphene has been the subject of numerous studies in recent years.

272 this phenomenon 40 years ago there have been numerous studies of the rutile single-crystal TiO2(110)

273 Despite numerous studies on the impact of ageing on individual m

274 Despite numerous studies suggesting the role of insular cortex i

275 t in afferent neurons.SIGNIFICANCE STATEMENT Numerous studies support that hair-cell ribbon size corr

276 Numerous studies that elucidate its composition were exc

277 schizophrenia remains controversial despite numerous studies to date.

278 Despite numerous studies, a painless, fast and direct method for

279 of this classification has been confirmed in numerous studies, and its basic concept remains valid.

280 Despite the importance and numerous studies, these efforts have mostly been underta

281 ells adapt to low O2 has been illuminated by numerous studies, with "reprogrammed" metabolism being o

282 The translation from numerous successful animal experiments on cardioprotecti

283 Numerous surveillance pathways sculpt eukaryotic transcr

284 KNOTTED1-types to regulate the expression of numerous target genes involved in hormone metabolism and

285 ine responses to 265 compounds, we uncovered numerous TFs whose activity interacts with anticancer dr

286 For TRS-breaking WSMs, despite numerous theoretical and experimental efforts, few examp

287 enzyme activities, which have been described numerous times but are not physiologically relevant.

288 e C-N bond has stimulated the development of numerous transition-metal complexes to effect chemo-, re

289 utive NIK expression decreased expression of numerous Treg signature genes and microRNAs involved in

290 the high levels of B7-H4 expression found in numerous tumor tissues and correlation of the level of e

291 r pancreatic cell lineages, we also identify numerous unipotent endocrine and ducto-endocrine bipoten

292 ring erythrocyte invasion, while identifying numerous unknown proteins likely to be involved in invas

293 his computational sensing technique can find numerous uses in global health related applications in r

294 mosquito Aedes aegypti is a major vector of numerous viral diseases, because it requires a blood mea

295 nd lysosome-localized protein that restricts numerous virus infections.

296 cal functions in other organisms, as well as numerous volatile compounds with undefined biological ro

297 The gut microbiota modulate host biology in numerous ways, but little is known about the molecular m

298 They are the targets of numerous widely used drugs, especially in the case of th

299 cosystem functioning by offering habitat for numerous wildlife species and influencing stand developm

300 Despite numerous works that prove this phenomenon, a method to a