ライフサイエンスコーパス: obese individual

1 Iron deficiency is common in overweight and obese individuals.

2 ular to reflect the situation in diabetic or obese individuals.

3 success in preserving insulin sensitivity in obese individuals.

4 rbic acid can be effective in overweight and obese individuals.

5 sceral fat compared with subcutaneous fat in obese individuals.

6 in the development of insulin resistance in obese individuals.

7 ons was 9.1% in NW individuals and 6.08% for obese individuals.

8 n between homeostatic and reward networks in obese individuals.

9 D) risk among normal-weight, overweight, and obese individuals.

10 strong lipolytic activity, are decreased in obese individuals.

11 mulae are inaccurate, especially in severely obese individuals.

12 Such activation may be disordered in obese individuals.

13 of type 2 diabetes in a large population of obese individuals.

14 t individuals, compared to 4.22% to 7.99% in obese individuals.

15 y larger than those in metabolically healthy obese individuals.

16 ss and blood pressure reduction in centrally obese individuals.

17 d processing unique to specific subgroups of obese individuals.

18 is significantly augmented in overweight and obese individuals.

19 identified the metabolic syndrome in equally obese individuals.

20 d in patients of normal weight compared with obese individuals.

21 tabolism of essential fatty acids focused on obese individuals.

22 in treatment of metabolic syndrome in mildly obese individuals.

23 ze and daily energy intake in overweight and obese individuals.

24 measures of atherosclerosis is diminished in obese individuals.

25 tify plasma Hsp60 concentrations in lean and obese individuals.

26 ne, a common air pollutant, are augmented in obese individuals.

27 and insulin-resistant normal-weight (NW) or obese individuals.

28 nd 5.6%, 8.3%, and 8.3%, respectively, in IS-obese individuals.

29 measures were greater for normal weight than obese individuals.

30 e 2 diabetes mellitus is heterogeneous among obese individuals.

31 his effect was not observed in overweight or obese individuals.

32 lly relevant to plasma lipids, especially in obese individuals.

33 elated to impaired FAO in HSkMC derived from obese individuals.

34 ble weight loss and metabolic improvement in obese individuals.

35 rdiovascular risks for metabolically healthy obese individuals.

36 piration rates were similar between lean and obese individuals.

37 sthma incidence and prevalence are higher in obese individuals.

38 g Prevotellaceae were highly enriched in the obese individuals.

39 entrations of saturated fatty acids found in obese individuals.

40 regain lost adipose stores in weight-reduced obese individuals.

41 se (NAFLD) is a common metabolic disorder in obese individuals.

42 ype 2 diabetes in comparison with lower-body-obese individuals.

43 nonspecific eating pattern sometimes seen in obese individuals.

44 ease the effectiveness of these therapies in obese individuals.

45 airment of the total vasodilator capacity in obese individuals.

46 y associated with risk of type 2 diabetes in obese individuals.

47 ate leptin signaling, limiting its action in obese individuals.

48 y be useful for regulating energy balance in obese individuals.

49 ased risk of psoriasis in both obese and non-obese individuals.

50 stronger effect observed in nonobese than in obese individuals.

51 the clinical situation of kidney donation by obese individuals.

52 ity and reduces the incidence of diabetes in obese individuals.

53 ol is able to improve glucose homeostasis in obese individuals.

54 trition, the latter exclusively in non-super obese individuals.

55 tween breakfast and health remain unclear in obese individuals.

56 the gut, characterize other vital organs in obese individuals.

57 cations in both normal weight and overweight/obese individuals.

58 cle microvasculature has not been studied in obese individuals.

59 and SAT volume were significantly higher in obese individuals.

60 ctors largely affecting the CVD prognosis of obese individuals.

61 a cancer prevention method in overweight and obese individuals.

62 increased risk of liver tumor development in obese individuals.

63 rgy-balance control and is often impaired in obese individuals.

64 nificant association with glaucoma status in obese individuals.

65 ences of cardiovascular events and cancer in obese individuals.

66 cause of nonalcoholic fatty liver disease in obese individuals.

67 n an acute study in healthy, overweight, and obese individuals.

68 improved physical health status for severely obese individuals.

69 tification and early intervention of at-risk obese individuals.

70 reduced circulating levels of adiponectin in obese individuals.

71 als also supports risk factor control in non-obese individuals.

72 ive approaches to resolve type 2 diabetes in obese individuals.

73 ent populations of severe obese and diabetic obese individuals.

74 r restoration of B lymphopoiesis in aged and obese individuals.

75 s and obesity-related metabolic disorders in obese individuals.

76 mm in NW individuals and 0.79 and 0.68 mm in obese individuals.

77 of OPN mRNA was higher in adipose tissue of obese individuals (0.13 +/- 0.04 vs. 0.04 +/- 0.01, P <

78 ant and normal weight (IR-NW), and 72 of 330 obese individuals (22%) were classified as insulin sensi

79 Fifty-two overweight and slightly obese individuals (30 men and 22 postmenopausal women, m

80 eight (40.0%; adjusted odds ratio, 1.68) and obese individuals (49.7%; odds ratio, 2.82) compared wit

81 In obese individuals, 6 weeks of extended morning fasting i

82 greater mean clinical attachment loss among obese individuals, a higher mean body mass index (BMI) a

83 s that may confer susceptibility to NAFLD in obese individuals across multiple ethnic groups.

84 In obese individuals, adipose tissue releases increased amo

85 bly, ANAs were less common in overweight and obese individuals (age-adjusted POR 0.74) than in person

86 A total of 5145 overweight and obese individuals aged 45 to 76 years with type 2 diabet

87 the associations among metabolically healthy obese individuals and 4 different presentations of incid

88 se-derived cytokine that is downregulated in obese individuals and after myocardial infarction.

89 pression is increased in adipose tissue from obese individuals and animals.

90 ipose tissue (BAT) is lower in overweight or obese individuals and in diabetes.

91 We examined FGF21 serum levels in lean and obese individuals and in response to dietary manipulatio

92 ly exclusively encountered in overweight and obese individuals and is associated with atherosclerosis

93 thway-based association studies in extremely obese individuals and normal-weight controls.

94 In severely obese individuals and patients with diabetes, accumulati

95 erlying increased breast cancer mortality in obese individuals and provide a novel preclinical ration

96 iatric surgery (MBS) leads to weight loss in obese individuals and reduces comorbidities such as type

97 vascular comorbidities are more prevalent in obese individuals and remain the basis for pretransplant

98 re to replicate and extend these findings to obese individuals and to examine the effects of differen

99 menting commensal, was markedly decreased in obese individuals and was inversely correlated with seru

100 ed by altering the nutrient load in lean and obese individuals and whether their microbiota are corre

101 s (NASH), 27 patients with NAFLD, 15 healthy obese individuals, and 39 healthy nonobese individuals (

102 omorbidity affecting white adipose tissue in obese individuals, and corrected impaired brown adipocyt

103 ents with type 2 diabetes, insulin-resistant obese individuals, and insulin-resistant offspring of pa

104 GE also occurs faster in obese individuals, and is associated with increased bloo

105 valent in human populations, particularly in obese individuals, and is characterized by progressive p

106 velopment, particularly among overweight and obese individuals, and offer a method for risk assessmen

107 nfluence daily energy balance, is reduced in obese individuals, and predicts future weight gain in th

108 Obese individuals are at greater risk for hospitalizatio

109 after short-term exercise training in older obese individuals are dependent on increased physical ac

110 However, not all obese individuals are insulin resistant, which confounds

111 Overweight and obese individuals are more likely to be insulin resistan

112 hanisms that hasten the onset of diabetes in obese individuals are not known, it is possible that the

113 mechanisms responsible for increased ECs in obese individuals are poorly understood.

114 Morbidly obese individuals are predisposed to a wide range of dis

115 ulin-stimulated SCAT glucose uptake rates in obese individuals are proportional to whole-body fat mas

116 Obese individuals are susceptible to comorbidities, incl

117 Formerly obese individuals are susceptible to metabolic disorders

118 A greater number of morbidly obese individuals are undergoing bariatric surgery, expa

119 sity rates may affect the decision to accept obese individuals as donors.

120 In the overweight and obese individual, as well as in persons with hypertensio

121 their metabolites, and PCP were measured in obese individuals at the initial moment of their enrolli

122 Several expert panels have recommended that obese individuals attempt to lose 10% of their initial b

123 erivascular fat were harvested from severely obese individuals before (n = 20) and 6 months after bar

124 PVAT anticontractile function in tissue from obese individuals before surgery.

125 Sarcopenic obesity was defined as obese individuals (BMI >/=30) in the lowest tertile of s

126 Thirty-one overweight or obese individuals (body mass index [BMI], 25-40 kg/m(2))

127 he odds of ADL impairment did not change for obese individuals but decreased by 34% among nonobese in

128 irmicutes were dominant in normal-weight and obese individuals but significantly decreased in post-ga

129 ascular benefit achieved with weight loss in obese individuals, but mechanisms are currently unknown.

130 ncreatic ductal adenocarcinoma (PDAC) and in obese individuals, but whether it contributes to PDAC de

131 Among obese individuals, C-allele homozygotes at rs8192675 had

132 Overweight and obese individuals carrying the AMY1-AMY2 rs11185098 geno

133 n binge eating phenotypes as the subgroup of obese individuals characterized by disordered eating.

134 t-term overfeeding in BMI-matched overweight/obese individuals classified as IS or insulin resistant

135 with low-grade inflammation of the tissue in obese individuals, contributes to the development of ins

136 In obese individuals, deregulation of a specific adipokine,

137 Most obese individuals develop hyperleptinemia and leptin res

138 With immunohistochemistry, we categorized obese individuals dichotomously as having inflamed fat (

139 Inflamed CLS+ obese individuals displayed higher plasma insulin, homeo

140 However, most obese individuals do not develop diabetes because they a

141 ean BMI and the percentage of overweight and obese individuals do not fully describe population chang

142 Around 25% of obese individuals do not show excess liver fat, whilst 1

143 A subset of obese individuals does not exhibit metabolically unfavor

144 ed by 43% (OR 1.43; 95% CI, 1.18-1.75) among obese individuals during this period, but did not change

145 reflect variable toxicokinetics in lean and obese individuals during times of increasing and decreas

146 All-cause 10-year mortality in obese individuals eligible for bariatric surgery can be

147 racted scientific attention-is often seen in obese individuals, especially those with severe obesity.

148 The prevalence of polyneuropathy is high in obese individuals, even those with normoglycemia.

149 Obese individuals exhibit an increase in pancreatic beta

150 n subcutaneous adipose tissues isolated from obese individuals exhibited reduced expression of APCDD1

151 samples by using pyrosequencing in morbidly obese individuals, explored before (0 mo), 3 mo after, a

152 In obese mice and obese individuals, Gpnmb expression was induced in ATMs.

153 Metabolically healthy obese individuals had a higher risk of coronary heart di

154 First, it was confirmed that obese individuals have higher cerebral 5-HT2A receptor b

155 pokine involved in metabolic regulation, and obese individuals have higher concentrations.

156 The reason why obese individuals have low circulating SHBG has been att

157 We tested the hypothesis that obese individuals have lower core temperatures than thos

158 Obese individuals have lower fasting plasma ghrelin leve

159 Although it has been shown that obese individuals have reduced natriuretic peptide level

160 Regular exercise can also improve S(I) in obese individuals; however, it is unknown whether exerci

161 sions to operate, differences among morbidly obese individuals in access to surgery, or patients' per

162 ited reports and the increased prevalence of obese individuals in Massachusetts between 1991 and 2001

163 2D risk among normal-weight, overweight, and obese individuals in up to 8,124 incident T2D cases.

164 iated microbial and metabolic alterations in obese individuals, including the decreased abundance of

165 rt failure in normal weight, overweight, and obese individuals increased with increasing number of me

166 93590 [A/C] and rs1378577 [T/G]) in morbidly obese individuals indicated that elevated ABCG1 expressi

167 In obese individuals, IRF5 expression is negatively associa

168 ic strategies for correcting such defects in obese individuals is challenging.

169 ce of the results for cancer in diabetic and obese individuals is that the initial stages of the proc

170 ependent of comorbidities commonly affecting obese individuals, is not clear.

171 cardiovascular risk factors are enriched in obese individuals, it has not been easy to dissect the e

172 fitness is protective against incident AF in obese individuals, its effect on AF recurrence or the be

173 nic Archaea in the gastrointestinal tract of obese individuals leads to the hypothesis that interspec

174 Obese individuals lose approximately 6 to 8 kg (approxim

175 est that ADF is a viable diet option to help obese individuals lose weight and decrease CAD risk.

176 Posture allocation did not change when the obese individuals lost weight or when lean individuals g

177 ontrolling pre-diabetes, weight reduction in obese individuals, lowering blood pressure in people wit

178 Mitochondria from obese individuals maintained higher (more negative) extr

179 standing the metabolic changes that occur in obese individuals may also help to elucidate more effect

180 lation of ENaC by metabolic abnormalities in obese individuals may be a likely cause of the hypertens

181 res of FGF2 or inhibit FGFR-1 in abdominally obese individuals may be important cancer prevention str

182 th body fat levels, adiponectin reduction in obese individuals may play a causal role in the symptoms

183 evels of SWS, as occurs in aging and in many obese individuals, may contribute to increase the risk o

184 However, a proportion of obese individuals might not be at an increased risk for

185 To maintain normothermia, therefore, obese individuals must increase their heat dissipation.

186 in subjects with normal glucose tolerance in obese individuals (n = 54) and a population-based sample

187 natriuretic peptide (BNP) concentrations in obese individuals ("natriuretic handicap") may play a ro

188 In obese individuals, no differential (FAST versus BFAST) e

189 by reducing levels of these risk factors in obese individuals not able to achieve sustained weight l

190 -related increase in mortality than severely obese individuals not undergoing surgery (P = .001).

191 d increase in mortality observed in severely obese individuals not undergoing surgery.

192 disorder (BED) were compared with 19 non-BED obese individuals (OB) and 19 lean control subjects (LC)

193 ing the concept of a natriuretic handicap in obese individuals observed in non-Hispanic whites to thi

194 Obese individuals often have low plasma adiponectin and

195 In obese individuals, oleoylethanolamide showed a trend tow

196 ing starvation, and is abnormally induced in obese individuals or those with diabetes.

197 functions, satiation, satiety, and weight in obese individuals over 16 weeks.

198 ar risk factors may also be decreasing among obese individuals over time.

199 th increasing BMI and were nonsignificant in obese individuals (p < 0.05 in nonobese, p > 0.1 in obes

200 ificant variability exists between similarly obese individuals, pointing to qualitative characteristi

201 In obese individuals, primary event rates were similar with

202 l adipocytes, and from healthy and unhealthy obese individuals, promoted comparable inflammatory resp

203 olic homeostasis; the enlarged adipocytes of obese individuals recruit macrophages and promote inflam

204 r data show that diet-induced weight loss in obese individuals reduces colorectal inflammation and gr

205 Metabolically healthy obese individuals (relative risk [RR], 1.24; 95% CI, 1.0

206 d striatal dopamine receptors are reduced in obese individuals, relative to lean individuals, which s

207 ontributing to greater infection severity in obese individuals remain unclear.

208 ight loss and lower vascular disease risk in obese individuals remains unknown.

209 may affect health parameters in a cohort of obese individuals reporting sleeping less than 6.5 hours

210 A morbidly obese individual's increased cardiac output requires adm

211 Nineteen obese individuals seeking treatment for binge eating dis

212 for new alternatives to treat obesity since obese individuals seem to have less brown adipose tissue

213 tence of healthy obese phenotypes because IS-obese individuals showed increased cardiometabolic risk.

214 From 2000 to 2014, the proportion of obese individuals significantly increased 44.9% and the

215 ns was analyzed in overnight-fasted lean and obese individuals subjected to a whole-mouth stimulation

216 In non-obese individuals, subjects with high triglycerides, hig

217 tive memory CD8 T cell responses and renders obese individuals susceptible to infection remains unkno

218 , chair use has replaced ambulation, so that obese individuals tend to sit for approximately 2.5 h/da

219 studies have found a lower risk of dying for obese individuals than for normal-weight individuals.

220 rs of H(2)-utilizing methanogenic Archaea in obese individuals than in normal-weight or post-gastric-

221 Compared to all non-obese individuals, the OR for depressive symptoms was hi

222 Among obese individuals, the prevalence of functional impairme

223 Among overweight and obese individuals, the prevalence of hypertension, impai

224 em and food-related behavior in binge-eating obese individuals, these results support a dissociation

225 her luminal enhancers of iron absorption) in obese individuals to improve iron status may have a limi

226 lity of these traits to predict responses of obese individuals to pharmacotherapy.

227 The failure of high levels of leptin in most obese individuals to promote weight loss defines a state

228 s of NAFLD progression (ranging from healthy obese individuals to those with steatosis), as well as r

229 not known if opioid use for chronic pain in obese individuals undergoing bariatric surgery is reduce

230 The relative odds of impairment for obese individuals versus normal-weight individuals signi

231 In obese individuals, visceral adipose tissue (VAT) is the

232 any treatment versus no treatment among non-obese individuals was 0.26 (95% confidence interval: 0.0

233 ociation of S/P with the metabolic status of obese individuals was further validated in a cross-secti

234 metabolism of nutrients in healthy lean and obese individuals, we investigated whether ingestion of

235 1994), the odds of functional impairment for obese individuals were 1.78 times greater than for norma

236 Overweight and obese individuals were assigned to the omega-3 arm (n =

237 mic H1N1 influenza A virus (pH1N1) outbreak, obese individuals were at greater risk for morbidity and

238 With respect to ADL impairment, odds for obese individuals were not significantly greater than fo

239 Fourteen obese individuals were re-examined after RYGB surgery.

240 Obese individuals were stratified into an obesity surger

241 Serum samples from obese individuals were taken before patients lost weight

242 e dataset, sampled from lean, overweight and obese individuals, were analysed to demonstrate parallel

243 ssue and systemic insulin resistance (IR) in obese individuals, which is represented by ADIPO-IR and

244 r percentage contribution to the sum PCBs in obese individuals, while higher chlorinated PCBs had a h

245 Our findings have primary relevance to obese individuals who are at an increased risk of develo

246 ass surgery and 7925 group-matched, severely obese individuals who did not undergo surgery were ident

247 y contributed to a decline in IQ, even among obese individuals who displayed evidence of the metaboli

248 rrant further investigation, particularly in obese individuals who have a reduced reliance on muscle

249 Thus, obese individuals who have low fruit and vegetable consu

250 cused on a unique subgroup of overweight and obese individuals who have normal metabolic features des

251 hanges in adiposity among 692 overweight and obese individuals who were randomly assigned to diets va

252 e successful use of lorcaserin in a morbidly obese individual with decompensated cirrhosis evaluated

253 We analyzed whether obese individuals with a "thrifty" phenotype, that is, g

254 s (miR-18a, miR-30e) were up-regulated among obese individuals with a healthy periodontium.

255 g to a 2 x 2 factorial design, 86 overweight/obese individuals with a large waist circumference and a

256 benefits of hesperidin 2S in overweight and obese individuals with a relatively healthy endothelium.

257 and weight fluctuation on rhythm control in obese individuals with AF.

258 ory fitness improvement on rhythm control in obese individuals with AF.

259 Obese individuals with an upper-body-fat distribution ha

260 lactulose:mannitol (Lac:Man) permeability in obese individuals with and without liver steatosis under

261 unction in obesity, and specifically compare obese individuals with and without metabolic syndrome (M

262 This mechanism may operate in obese individuals with chronic inflammation, thus making

263 style behavior intervention in overweight or obese individuals with diabetes mellitus.

264 lic effects of GCKR inhibition in overweight/obese individuals with diabetes mellitus.

265 tention to prevention of vascular disease in obese individuals with diabetes.

266 alcoholic steatohepatitis is prevalent among obese individuals with excessive caloric intake, insulin

267 wnregulated in the omental adipose tissue of obese individuals with extreme insulin sensitivity and,

268 s (all men; mean age, 37 years), and in five obese individuals with hyperlipidemia or diabetes (four

269 lel study was conducted in 50 overweight and obese individuals with increased waist circumference and

270 human adipose-derived stem cells (ASCs) from obese individuals with MNCs and analyzed their reciproca

271 u-opioid receptor antagonist, GSK1521498, in obese individuals with moderate binge eating.

272 and hepatic mRNA expression were measured in obese individuals with NAFLD or NASH.

273 During a mean follow-up of 5.4 years, obese individuals with no metabolic abnormalities had a

274 escents (age range: 12-16 yr) underwent MRI: obese individuals with OSAS (n = 49), obese control subj

275 (miR-30e, miR-106b) were up-regulated in non-obese individuals with periodontal disease.

276 d local immune and inflammatory responses in obese individuals with periodontitis may explain the agg

277 ue biopsies collected from normal weight and obese individuals with periodontitis; miRNA expression p

278 rpose of this study was to determine whether obese individuals with reduced adipose tissue inflammati

279 Heterogeneity exists among obese individuals with respect to the neural correlates

280 Among 4,021 obese individuals with sinus rhythm and no history of at

281 ry fitness predicts arrhythmia recurrence in obese individuals with symptomatic AF.

282 scular composite end points among overweight/obese individuals with T2D and whether a lifestyle inter

283 ncluded in this report were 3,845 overweight/obese individuals with T2D who provided consent for gene

284 than in nonobese individuals, especially in obese individuals with the TaqI A1 allele.

285 These hormones are both often elevated in obese individuals with therapy-resistant hypertension.

286 mptoms was higher in metabolically unhealthy obese individuals with two or more metabolic risk factor

287 pecies (DCAS) was significantly increased in obese individuals with type 2 diabetes (T2DM) from a cas

288 riction and exercise-mediated weight loss in obese individuals with type 2 diabetes is associated wit

289 itus support and education arm in overweight/obese individuals with type 2 diabetes mellitus with tri

290 inge eating (BE) is common in overweight and obese individuals with type 2 diabetes mellitus, but lit

291 Overweight and obese individuals with type 2 diabetes who stop BE appea

292 tent of food consumption among overweight or obese individuals with type 2 diabetes.

293 Overweight/obese individuals without apnea have a moderately compro

294 -based analysis demonstrated that overweight/obese individuals without apnea rely on both more favora

295 Obese individuals without cardiac disease with (OB/MS+,

296 etic subjects compared with those in equally obese individuals without metabolic syndrome.

297 efined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been

298 hich results in an ever-increasing number of obese individuals worldwide.

299 seen a rapid expansion of the proportion of obese individuals worldwide.

300 stematically evaluated within overweight and obese individuals, yet its use within pregnancy has not