ライフサイエンスコーパス: observation

1 d using the data of the past decade (>200000 observations).

2 all-cause or prostate-cancer mortality than observation.

3 y with cumulative exposure during open-label observation.

4 6) and death (0.74, 0.64-0.86) compared with observation.

5 ) died within 1 y during 1318 child-years of observation.

6 atic vitreolysis, enzymatic vitreolysis, and observation.

7 prostate cancer to radical prostatectomy or observation.

8 ents with NDMM when compared with placebo or observation.

9 al dynamics have escaped direct experimental observation.

10 olphins (Sousa sahulensis) over ten years of observation.

11 tion of sedation are needed to confirm these observations.

12 mbined with sediment mixing, can explain the observations.

13 mission project, showed close agreement with observations.

14 ucleus, has been challenged by contradictory observations.

15 agophore shape, consistent with experimental observations.

16 en fieldnotes recorded, to contextualise the observations.

17 ch is capable of explaining the experimental observations.

18 stem is used to compare and substantiate our observations.

19 es of the elastic moduli from purely optical observations.

20 erm depression, consistent with experimental observations.

21 s important when reconciling inventories and observations.

22 his view is challenged by recent contrasting observations.

23 ce-distance curves and include the following observations: (1) force-distance curves showed detachmen

24 g 485322 person-years (median, 6.7 years) of observation, 5750 (8.4%) sustained an incident MOF, 1579

25 Based on these observations, a model of GenK catalysis is proposed wher

26 S benefit in patients who received AC versus observation after RNU for pT3/T4 and/or pN+ UTUC.

27 These observations allow us to understand how ZIF-8 crystals s

28 To determine if observation alone after nephrectomy in very low-risk Wil

29 Expansion of an observation alone strategy for low-risk Wilms tumor inco

30 Our observations also suggest that, when news coverage is un

31 Based on these observations, an interaction-relaxation model is develop

32 umatic patients should be kept under medical observation and abdominal CT should be preferred for ima

33 , the hairs of these mice interfere with the observation and imaging of engrafted tissues.

34 tion cannot be brought by pure morphological observation and, to our knowledge, brings a new perspect

35 Our observations and analyses indicate that, at the time of

36 rid simulations corroborate our experimental observations and demonstrate a beam-like hot electron tr

37 Based on experimental observations and DFT calculations, evidence is provided

38 region-years) while accounting for imperfect observations and grounding our findings in species-level

39 Here, using observations and numerical model simulations, we show th

40 Overall, our experimental observations and physical model establish general rules

41 elf-consistent field theory reinforces these observations and predicts that LAMP is thermodynamically

42 imate models and compare them with satellite observations and reanalysis data.

43 assembly criteria based on crystallographic observations and subsequently quantify the strengths of

44 These features are in agreement with observations and suggest that the correct parameterizati

45 GF23, discuss potential mechanisms for these observations and their public health implications, and e

46 lations allow us to explain the experimental observations and to give experimentally testable predict

47 ational analysis has enabled the generation, observation, and characterization of these highly elusiv

48 cal documentation and pill counts for direct observation, and self-reports, pill counts, and medicati

49 e to deforestation is consistent with recent observations, and conversion of mid-latitude natural for

50 These observations apply equally to the study of other oral di

51 Our observations are consistent with a predictive model that

52 Collectively, these observations are consistent with the conclusion that MPn

53 Both these observations are consistent with the role of beta-cateni

54 These observations are important for further informing Ebola v

55 The crystallographic observations are reinforced by protein-protein binding a

56 and offer potential reasons to explain this observation, as well as propose a recommended schema for

57 of convincing epidemiologic and experimental observations, as discussed in this article.

58 To measure variation in the use of observation at the urologist level by disease risk strat

59 of persistent and homogeneous severe weather observations at climate scales while the detailed physic

60 Previous observations at Rifle, Colorado, have shown that fine gr

61 Consistent with this observation, atypical meningiomas exhibit upregulation o

62 all models except JeDi and VISIT compared to observation-based average k), likely contributing to und

63 Our observations can be explained if ACh and glutamate are r

64 Understanding how the paradox biases local observations can inform better measurements of network s

65 ion information on water supplies, satellite observations can provide essential insight.

66 served values (P = 0.044) but not using last observation-carried forward method.

67 veloped, pilot tested, and analyzed a direct observation checklist designed to assess the extent to w

68 rthermore, concurrent validity of the direct observation checklist is demonstrated by statistically s

69 The in situ observations, combined with large-scale reactive molecul

70 These observations contribute to an appreciation of the roles

71 These observations contributed to the hypothesis of reduced so

72 igned (1:1) to receive sodium thiosulfate or observation (control group) in addition to their planned

73 cephalopathy, and whether human neuroimaging observations converge with computational predictions.

74 This observation correlated with increased mast cell activati

75 These observations demonstrate that Ly6C(+) macrophage apoptos

76 Our observations demonstrate that the production of both nuc

77 These observations demonstrate that the stabilization of wides

78 These observations demonstrate that tyrosine 470 and 88 are cr

79 Observations: Depression presents with the same symptoms

80 This observation does not support the prediction of the time-

81 e imaging modalities, strategic longitudinal observation during weight restoration, and large-scale d

82 These observations elucidate the role of roughness in colloid

83 These observations encourage investigation of the neurobiology

84 Explaining these observations, enhancers show TF-dependent binding of the

85 At each observation, ERI was measured using validated scales, an

86 These observations establish BiP and its J domain co-chaperone

87 Together, these observations establish that small molecules that bind to

88 Here we report two unique observations; first, that colloidal suspensions, at suff

89 ogist-level variation was seen in the use of observation for intermediate-risk disease (11.1%; range,

90 tween the physician-level estimated rates of observation for low-risk and high-risk disease was asses

91 ciation between the urologist-level rates of observation for men with low-risk and high-risk prostate

92 open-source tool, xiFDR, that implements our observations for routine application.

93 Unsolicited patient observations for the patient's surgeon in the 24 months

94 hased by US households in 2007-2012 (345,193 observations from 110,539 unique households).

95 tative longitudinal studies totaling 176,720 observations from 41,567 children and adults.

96 ased on >200 000 spatiotemporal phenological observations from across the United Kingdom.

97 As such, our finding contradicted observations from cell culture systems.

98 Consequently, observations from coral communities under naturally occu

99 hlorophyll fluorescence, and carbon monoxide observations from multiple satellites.

100 iabetes and 3.8% vs 7.3% for diabetes in 572 observations from participants with SCT and 6877 observa

101 rvations from participants with SCT and 6877 observations from participants without SCT; P<.001 for b

102 Observations from probes far from the Earth are not affe

103 Performance against the observations from single-factors treatments was also rel

104 Our phenotypic observations further suggested that Afh mutants failed t

105 ide group and 23.5 months for the placebo or observation group (hazard ratio, 0.48; 95% CI, 0.41 to 0

106 , 132 patients were randomly assigned to the observation group (n=68) or SRS group (n=64), with 128 p

107 maintenance group and 603 in the placebo or observation group).

108 e (three from the SRS group and one from the observation group).

109 ) or nodal observation with ultrasonography (observation group).

110 However, this observation has never been tested in vivo.

111 These observations have encouraged the development of therapeu

112 These observations have implications for environmental fate an

113 These observations highlight the serotype-dependent heterogene

114 These observations, however, should be taken cautiously as mul

115 is) in a manner consistent with the clinical observations (i.e., LPS upregulated Wnt5a and downregula

116 These observations illustrate an unexpected yet prominent phen

117 These observations imply that pre-excision step(s) during OGG1

118 hole-genome regression models by subsampling observations in each round of a Markov Chain Monte Carlo

119 Based on the observations in humans, mechanistic experiments were des

120 Here, using satellite observations in June-August from 2006 to 2011, a global

121 We confirmed and expanded observations in mice that variations in dietary Na(+) in

122 RNA targeting principles are consistent with observations in other species, but with expanded pairing

123 d major depressive disorder, consistent with observations in schizophrenia.

124 We described the observations in terms of anion adsorption and surface ox

125 Our observations in the low field region are consistent with

126 These observations indicate that blocking peripheral sensory i

127 These observations indicate that changes in differentially hyd

128 Cosmological observations indicate that dark matter makes up 85% of a

129 These observations indicate that environmental cytokines play

130 These observations indicate that genes under weaker selective

131 Our observations indicate that Nrdp1 physically interacts wi

132 These observations indicate that our novel profilin1 mutant mo

133 Altogether, these observations indicate that Pi uptake by S. aureus differ

134 These observations indicate that the self-assembly of small mo

135 These observations indicate that the signal intensity of the M

136 Continued input of observations into FRED to fill gaps in trait coverage wi

137 An unexplained observation is that gut species composition varies widel

138 The second observation is the discovery, in the inner layer of the

139 y of physical laws consistent with empirical observations is at the heart of (applied) science and en

140 Reconciling these observations is engendering active debate about the phys

141 A mechanism consistent with these observations is presented that differs from other charac

142 d, but the in vivo relevance of the in vitro observations is still unclear.

143 These combined observations lead us to propose that the natural process

144 ht to target RNA polymerase, but conflicting observations leave the mechanisms elusive.

145 This observation led us to explore the possibility that resid

146 This observation led us to speculate as to whether our data m

147 These observations led us to propose a metabolic model for aut

148 These latter observations make obestatin a promising target for vascu

149 These observations may give clues for creating melanin-based r

150 These observations not only reveal this fundamental integrativ

151 We also discuss the recent observation of a large superconducting spin-valve effect

152 This is the first observation of a PVS closure in connection with an abnor

153 This result is the first direct observation of any BAR-domain protein dynamics in vivo u

154 This is the first experimental observation of Bi-B double and triple bonds, opening the

155 Therefore, an in situ observation of chemical and mechanical characteristics d

156 lyses(PCA) of RRS simulations agree with the observation of distinctive impact from individual residu

157 The intermittent observation of DOBV before 2010 can be interpreted as re

158 ectroscopy, or electrical methods, no direct observation of DPD at the atomic level has been reported

159 The simultaneous observation of electrons and holes with extreme ultravio

160 e detailed; the results demonstrate a direct observation of enzymatic activity in solution by the sen

161 Here, we report the observation of excitons in bilayer graphene (BLG) using

162 tomic ions has led to advances including the observation of exotic phases of matter, the development

163 A clear answer hinges on observation of hallmarks of a reversible phase transitio

164 The continued observation of heterogeneity of treatment response by ba

165 Continuous observation of livestock by farm staff is impractical in

166 e functional implications of the decades-old observation of mitotic linker histone phosphorylation, s

167 important for bacterial pathogenesis, direct observation of Mn(II) sequestration from bacterial Mn(II

168 this extreme localization of BISER by direct observation of nano-scale coherent x-ray sources in a la

169 Direct observation of nanoparticles in the early stages of grow

170 Based on the observation of natural hydrothermal pyrites, As(-I) is u

171 Twenty hours of observation of nursing staff's interactions with patient

172 Combined, this enables observation of root tips growing along the natural gravi

173 omote preferential delithiation, whereas the observation of strain-induced cracking suggests mechanic

174 The observation of such a time crystal opens the door to the

175 Here we report the observation of the 1S-2S transition in magnetically trap

176 hase transition in VO2 This technique allows observation of the bulk material in real time, follows t

177 activation reaction was too fast for direct observation of the intermediates, but they could be caug

178 iles post-elutriation, as exemplified by the observation of the maturation of a second flagellar basa

179 ication of the amount of active catalyst and observation of the molecular weight distribution (MWD) o

180 an instrumental tool, in vivo studies allow observation of the overall effect on a living organism.

181 on sensitization phenomenon resulting in the observation of the typical green emission of Tb.

182 hibian malformations, suggest that increased observations of abnormal amphibians are associated with

183 Therefore, any observations of altered adipose tissue insulin sensitivi

184 Here we report observations of an emission line of singly ionized carbo

185 productivity, and soil carbon estimates with observations of annual Rs from the Global Soil Respirati

186 Observations of binary stars containing an accreting bla

187 We combined 3 y of highly detailed visual observations of Bornean orangutans with high-resolution

188 r clinical quality, we used data from direct observations of care to calculate providers' adherence t

189 Here we report direct electron-microscopic observations of deposition growth of aligned ice crystal

190 g a data set comprising > 216 000 world-wide observations of Fabaceae, spanning three orders of magni

191 n ( 465 Ma) accords with a number of similar observations of healed lesions observed in trilobites.

192 Microscopic observations of hydathodes six days postinoculation indi

193 t 2016, the Juno spacecraft acquired science observations of Jupiter, passing less than 5000 kilomete

194 Here we report observations of LHS 1140b, a planet with a radius of 1.4

195 high-speed atomic force microscopy (HS-AFM) observations of membrane-reconstituted GltPh at work.

196 Consistent with previous observations of species-specific regulation of immunity

197 Recent observations of switching of magnetic domains in ferroma

198 The observations of the additive effects of advanced and del

199 echanism is deemed inadequate to explain the observations of the eddy-covariance systems, which must

200 ltaneous infrared, optical, x-ray, and radio observations of the Galactic black hole system V404 Cygn

201 (i.e., 59%-61% median identity), on par with observations of the most distantly related species pairs

202 subionospheric very low frequency radiowave observations of the NAA 24.0 kHz transmitter, Cutler, Ma

203 rs and microcores, and coupled these data to observations of water potential, soil moisture, and vapo

204 g were affected, further supporting previous observations on its importance in malignant transformati

205 Using century-long observations on masting (the MASTREE database) and data

206 61 screening MR imaging studies, covering an observation period of 7007 women-years.

207 After a median observation period of approximately 6 years from first t

208 inical practice and with a sufficiently long observation period outside the clinical trial scenario.

209 thod to account for use before and after the observation period.

210 0 adults who started chemotherapy during the observation period.

211 sed their HADS scores by 6 points during the observation period.

212 These sparse but robust observations pose a problem in that the coesismic uplift

213 These observations provide a mechanistic link between EPHB rec

214 llowed prospectively (1644.5 person-years of observation [PYO]), 371 HCV incident infections resulted

215 Overall, our observations raise the possibility that local production

216 Geodetic and field observations reveal surface ruptures along at least 12 m

217 Video observations revealed a single species, Siganus virgatus

218 These observations rule out simple acoustical cues as a basis

219 Altogether, combining observation scales and analytical approaches enabled to

220 indings are important for hydrology study in observation scarce mountainous areas, water resources an

221 Taken together, our theory and experimental observations show how soft hydraulics can regulate the s

222 Our observations show that the memory of subtle differences

223 Our observations show that the N terminus affords the switch

224 tailed PANS are used to explain experimental observations; specifically, we discuss interpretation of

225 similar to those observed for P vivax These observations stress the value of P cynomolgi as a model

226 ffects of LCs on pulmonary epithelia and our observations strongly suggest that LCs pose a more sever

227 Observations: Subclinical AF is asymptomatic, short in d

228 These observations suggest a novel "nonimmune" modality for in

229 These observations suggest a potential role for CT-1 in the re

230 These novel observations suggest that allergic airway inflammation i

231 These observations suggest that ARHL is associated with a decr

232 These observations suggest that biochemically equivalent organ

233 Together, these observations suggest that C. albicans-P. aeruginosa cros

234 The observations suggest that electronic symmetry is of grea

235 These observations suggest that large igneous provinces charac

236 The observations suggest that the uveitis that accompanies j

237 These observations suggest that therapeutic interventions shou

238 Our observations suggest that, although relatively uncommon,

239 sults are intriguingly in line with previous observations suggesting some transcription-independent (

240 These in vitro and in vivo observations support further evaluations of pretargeting

241 Taken together, these observations support the conclusion that the HTLV-1 CA N

242 These observations support the hypothesis that interactions be

243 mpared with other tissues among primates, an observation that calls for reassessment of RNA expressio

244 Most troublesome is the observation that cancer cells that survive treatment sti

245 tion and repression of ClaH corroborated the observation that clathrin does not play an important rol

246 The observation that DMF stimulates mitochondrial biogenesis

247 The unexpected observation that function can be derived from expanded,

248 other physically attractive neighborhoods-an observation that is consistent with the "invasion" theor

249 Rakova et al. report the unexpected observation that long-term high salt intake did not incr

250 mains lack the flexible hinge in BiFae1A, an observation that may partly provide a molecular basis fo

251 cing, and metabolite profiling supported the observation that neoplasm is triggered by a decrease in

252 Here we report the surprising observation that SIVmac239, a commonly used model virus,

253 Our observation that the ability of dexamethasone to modulat

254 The observation that the alpha4 E loop is involved suggests

255 table for such risk assessment, based on the observation that the innate restriction factor MxA repre

256 The observation that the majority of virions exclusively exp

257 The observation that the soluble factors BAFF, IL-2, and IL-

258 Observations that adipocyte RBP4 mRNA increases in paral

259 n through positive feedback, consistent with observations that behavioral state influences reticular

260 experimental results further support earlier observations that large molecular weight BrC compounds f

261 This is supported by further observations that replacement of extracellular Cl(-) wit

262 men in a trial with serial weight data (7310 observations) that were available before and during preg

263 Consistent with this observation, the immunoglobulin (Igh) gene deamination a

264 In agreement with this observation, the induced overexpression of NEK6 reduced

265 Consistent with these observations, the mRNAs of SOCS family genes encoding th

266 Observations: The main value of testing for viruses in c

267 As an additional observation, there was strong inter-individual variabili

268 These predictions agree with experimental observations, thereby providing, to our knowledge, new i

269 Median observation time was 12.9 years from primary diagnosis (

270 ted laboratory-confirmed cases occurred over observation times of 106631 and 23769 days, respectively

271 the toxicity test (tested concentrations and observation times).

272 We used this new observation to infer that the LNP proportions of more th

273 owever, the physiological relevance of these observations to adult ovarian function is unknown.

274 orms": a quantitative mapping from empirical observations to prototypical realizations of the underly

275 ere we use a numerical model calibrated with observations to show that interactions between ice flow,

276 We sought to evaluate the effects of formal observation training in the visual arts on the general a

277 ome, whereas treatment in a facility with an observation unit and presence of outpatient follow-up wi

278 s likely to be treated in a facility with an observation unit.

279 ble with previously reported air temperature observations used in predicting Rs and is the dominant d

280 We explain these observations using an analytically solvable, well-mixed

281 This novel observation warrants further studies.

282 Median duration of observation was 4.6 years, and 16.5% (n = 390) either di

283 m these models, the estimated probability of observation was calculated for each urologist within eac

284 The mechanism of this novel observation was further investigated through the multipl

285 This observation was paralleled by a compromised TDG (thymine

286 An unexpected observation was that the ASGR also appears to play a rol

287 Based on these observations we propose a model where in the hydrated st

288 Based on our observations, we argue that the subglacial environment i

289 With the observations, we built a three-step prediction model, na

290 Based on these observations, we develop a summative model wherein the P

291 To provide a molecular rationale for these observations, we study the Dbl-homology (DH) and Pleckst

292 Based on these and previous observations, we suggest that CENP-F might act as a tran

293 Here, to reconcile these observations, we track the evolution of oceanic Fe-conce

294 These observations were consistent with suppression of a musca

295 Finally, these observations were mirrored in transcriptomic and histolo

296 investigated by SEM and TEM imaging, and the observations were used to guide the optimisation of the

297 Observations: While there is an emerging role for germli

298 -node dissection (dissection group) or nodal observation with ultrasonography (observation group).

299 an be constrained by combining seismological observations with mineral physics elasticity measurement

300 ely unobserved processes: transmission, case observation, within-host pathogen dynamics and mutation.