ライフサイエンスコーパス: observation of

1 A case series from a descriptive observation of 14 patients with HR after anti-PD-1/anti-

2 The observations of 54,894 subjects were analyzed.

3 anion is confirmed spectroscopically by the observation of a blue shift of the CO stretching mode in

4 tic metal-ligand host and provides the first observation of a conformational selection mechanism (as

5 Based on the observation of a decelerating decrease of 2-MIB with tim

6 Here we present a direct observation of a double hydrogen atom transfer (tautomer

7 baseline resolved, four dp6 isomers, and the observation of a dp3 oligosaccharide.

8 transitions near the Weyl points through the observation of a Fano resonance in the Weyl semimetal Ta

9 ly, our findings may explain a past clinical observation of a GABAA-R PAM reducing HbA1c levels in di

10 anifold ((5)MLCT <-- (5)MC) and leads to the observation of a greatly increased MLCT lifetime of 14.0

11 We also discuss the recent observation of a large superconducting spin-valve effect

12 This behavior is the first observation of a lift-generating flipper-stroke for prop

13 The observation of a minimum of 640 J sr(-1) directly backsc

14 Observation of a network of interchain interactions, as

15 nantioselective reaction; in particular, the observation of a nonlinear relationship is usually inter

16 We also extended the previous observation of a possible "lux box" LuxR binding site up

17 n was scheduled for 1 year and stopped after observation of a primary end point.

18 This is the first observation of a PVS closure in connection with an abnor

19 Our observation of a second order rate law allows us to dist

20 Observation of a sigmoid functional response may thus ar

21 Here we report observations of a far-infrared-luminous object at redshi

22 Previous observations of a higher risk of child autism spectrum d

23 This study reports on observations of a lens-shaped structure within thermocli

24 Here we report observations of a prominent but red optical flash that a

25 hibian malformations, suggest that increased observations of abnormal amphibians are associated with

26 h-redshift galaxies has been studied through observations of absorption line systems toward backgroun

27 In summary, we report the first observation of abundant copy number variations on neurop

28 Expectation of reward can be shaped by the observation of actions and expressions of other people i

29 Imitation and observation of actions and facial emotional expressions

30 Under placebo, we replicated previous observations of adaptive coding in the midbrain and vent

31 Real-time observations of adsorption/desorption at the molecular-s

32 from the climate manipulations and long-term observations of adult populations revealed that heating

33 ne-learning approach that combines satellite observations of AGB with climate data across the Amazon

34 s, the detection is made by simple naked-eye observation of agglutinates without any access to the ki

35 Differences among these are ascribed to the observation of alpha-end and chain-length dependent solv

36 Therefore, any observations of altered adipose tissue insulin sensitivi

37 radiative transfer models (RTMs) with field observations of Amazon forest leaf and canopy characteri

38 ne aerosol reference tank were compared with observations of ambient SSA observed at two coastal loca

39 Weekly observation of ammonium over a twelve-year period reveal

40 The direct observation of amorphous barium carbonate (ABC), which t

41 lusively surface-dominated transport via the observation of an ambipolar surface quantum Hall effect

42 sis, we explore the factors underpinning the observation of an amplified response of summer LSWT to S

43 ing that our theory can reproduce the recent observation of an unusually large zero-energy peak in a

44 and pathway analyses supported long-standing observations of an association between immune-mediated d

45 Here we report observations of an emission line of singly ionized carbo

46 In this article, we review the observations of anions in interstellar clouds, circumste

47 productivity, and soil carbon estimates with observations of annual Rs from the Global Soil Respirati

48 Here we report on the observation of another threshold magnetic field never en

49 This result is the first direct observation of any BAR-domain protein dynamics in vivo u

50 Observations of arm movements evoked by vestibular stimu

51 Here, we combine aircraft and tower observations of atmospheric CO2 with remote sensing data

52 s (not just mating), which accounts for many observations of attractiveness-based preferential treatm

53 This is the first experimental observation of Bi-B double and triple bonds, opening the

54 However, experimental observations of BICs have been limited to passive system

55 Observations of binary stars containing an accreting bla

56 We combined 3 y of highly detailed visual observations of Bornean orangutans with high-resolution

57 results are consistent with the experimental observation of both conformations.

58 In conclusion, our observation of brain insulin resistance in multiple syst

59 Spaceborne observations of carbon dioxide (CO2) from the Orbiting C

60 Inclusion criteria were met by 32,531 observations of care in 4,354 facilities.

61 r clinical quality, we used data from direct observations of care to calculate providers' adherence t

62 do scanning transmission electron microscopy observations of cathodic reactions in a liquid-cell Li-O

63 d by intense near-infrared laser pulses, our observation of CED in the XUV range suggests that this p

64 The results compare well with the phenotype observations of cells on different substrates.

65 mmation is associated with the controversial observation of cerebral hypermetabolism in aging WT mice

66 Therefore, an in situ observation of chemical and mechanical characteristics d

67 We conducted in situ observations of cleaning interactions between bluestreak

68 oreactor (IsoCaRB) that permitted continuous observations of CO2 production rates, as well as sequent

69 In conclusion, real-time observation of composite placement and 3D quantification

70 (iii) The observation of conformational changes on DXPS provides s

71 t examples of a sexual 'arms race' come from observations of correlated evolution in sexually antagon

72 Here we report the first observation of crystal plasticity, identified using elec

73 Direct observation of crystallization within surface pockets us

74 Here we report the observation of dangling-bond magnetic polarons (DBMPs) i

75 uld replicate counter-intuitive experimental observations of decreased activation of Ca2+/CaM-depende

76 The absence of observations of deep-sea scleractinian reefs in the Cent

77 Here we report direct electron-microscopic observations of deposition growth of aligned ice crystal

78 Based on observations of DGR abundance, function and evolutionary

79 n of the steroid metabolites is based on the observations of different patterns of sodium acetate clu

80 t its inherent low sensitivity prohibits the observation of diluted samples.

81 Additionally, our results are the first observations of direct biological alteration of REE dist

82 nce dispersal are based on direct ecological observations of dispersing individuals, while indirect e

83 sparency of the new IREs allows the spectral observation of displaced water libration bands at ca. 73

84 Here we report observations of distinct, high-energy, downward, discret

85 lyses(PCA) of RRS simulations agree with the observation of distinctive impact from individual residu

86 The intermittent observation of DOBV before 2010 can be interpreted as re

87 ectroscopy, or electrical methods, no direct observation of DPD at the atomic level has been reported

88 aningfully sorted according to the number of observations of each transformation in medicinal chemist

89 unique opportunity to perform direct imaging observations of Earth-sized exoplanets with high signal-

90 The simultaneous observation of electrons and holes with extreme ultravio

91 undergo a deracemization process that allows observation of enantiomerically enriched compounds.

92 Here, we report the observation of enhanced thermoelectric response in polyc

93 Together with observations of enhanced cellular stress after overturni

94 e detailed; the results demonstrate a direct observation of enzymatic activity in solution by the sen

95 ion of distinct CD8(+) T cell fates, but the observation of equivalent expression of TFs among differ

96 Here, we report the observation of excitons in bilayer graphene (BLG) using

97 tomic ions has led to advances including the observation of exotic phases of matter, the development

98 g a data set comprising > 216 000 world-wide observations of Fabaceae, spanning three orders of magni

99 audit of facility infrastructure and direct observation of family planning, antenatal care (ANC), si

100 Recent observations of feeding dynamics in small animals showed

101 in classical systems, no direct experimental observation of Fermi arcs in momentum space has been rep

102 Here, we report the observation of ferroelectric and ferroelastic nanodomain

103 Here we report the observation of first- and second-order buckling transiti

104 tigation, sound stimuli were chosen to allow observation of fixed cortical oscillations driven by con

105 Observations of fluctuating gene expression and phenotyp

106 kJ mol(-1), consistent with the experimental observation of formation of a stable CO2 adduct.

107 Here we report the observation of fully valley- and spin-polarized LLs in h

108 Here we report first observations of Gigantic Jets in Indian subcontinent ove

109 from this model agreed well with flux tower observations of GPP (R(2 ) = 0.68; P < 0.0001), demonstr

110 we present a global synthesis of 2,200 root observations of >1,000 species along biotic (life form,

111 nto the structural factors important for the observation of guest binding.

112 A clear answer hinges on observation of hallmarks of a reversible phase transitio

113 However, surface observations of HCHO are sparse and the EPA monitoring n

114 n ( 465 Ma) accords with a number of similar observations of healed lesions observed in trilobites.

115 ed photoemission spectroscopy, we report the observation of helical spin texture in monolayer, centro

116 The continued observation of heterogeneity of treatment response by ba

117 Here we report the observation of high-harmonic generation from amorphous f

118 or this inhibited state is unknown, previous observations of higher-order MinE self-association may e

119 The direct observation of highly oxygenated intermediates for the a

120 is paper presents the derivation of HO2 from observations of HO2NO2 and NO2 in metropolitan Atlanta,

121 Clinical observation of HR during anti-PD-1/anti-PD-L1 therapy fo

122 This mechanism is consistent with observations of hybrid earthquakes.

123 Microscopic observations of hydathodes six days postinoculation indi

124 the first direct, noncatalytic quantitative observation of hydrogenolysis of acyl dicarbonyls.

125 The observation of hyperfine structure in atomic hydrogen by

126 Using behavioral observations of identifiable individual sailfish hunting

127 These results are consistent with previous observation of IDPs under the influence of synthetic pol

128 This observation of "incomplete neutralization" is associated

129 Finally, we show that the experimental observations of increased average crystallite size with

130 rating lymphocytes and, through longitudinal observation of individual animals, distinguish respondin

131 despite extensive research in Greenland and observations of individual drainage systems in Antarctic

132 h have been optimized prior to forecast with observations of influenza incidence and data assimilatio

133 Observation of intact fluorescently-tagged MkMPs inside

134 CDI was first described based on observations of interbacterial killing and has been assu

135 Here we report observations of iPTF14hls, an event that has spectra ide

136 dividual isomers at very low temperature and observations of isomer mixtures at ambient conditions.

137 t 2016, the Juno spacecraft acquired science observations of Jupiter, passing less than 5000 kilomete

138 se results constitute the first experimental observation of kink-antikink solitary wave propagation i

139 The observation of Kohn anomalies in the surface phonon disp

140 subthalamic nucleus consistent with previous observations of lateralization of emotionally evoked act

141 Here we report observations of LHS 1140b, a planet with a radius of 1.4

142 f the fluorine-free moiety, supported by the observation of likely metabolites such as n:3-fluorotelo

143 Continuous observation of livestock by farm staff is impractical in

144 Growth experiments and observations of living progenitors of these crops can pr

145 Field and laboratory observations of LNG storage tanks were used for model de

146 represent a rare example in which the direct observation of London dispersion forces is possible in s

147 The model is constrained to observations of long-lived species, meteorological param

148 nhibition, consistent with the physiological observation of lower cell yields and reduced dechlorinat

149 Widespread observations of malformed amphibians across North Americ

150 focus on DNA methylation and the collective observations of many studies being conducted within the

151 high-speed atomic force microscopy (HS-AFM) observations of membrane-reconstituted GltPh at work.

152 charov and Struzhkin present comments on our observation of metallic hydrogen.

153 e functional implications of the decades-old observation of mitotic linker histone phosphorylation, s

154 MP9 in the tooth development was examined by observation of Mmp9 knockout (Mmp9-/-) mouse phenotype,

155 important for bacterial pathogenesis, direct observation of Mn(II) sequestration from bacterial Mn(II

156 We report novel in situ speciated observations of monoterpenes (alpha- and beta-pinene, my

157 Direct observation of MTs in working myocytes suggests a spring

158 We present observation of multi-soliton complex generation in mode-

159 r knowledge, this study represents the first observation of multiday persistence of an indoor aerosol

160 the core are necessary preconditions for the observation of multiexciton multi-colour emission.

161 me optical losses at 83 K, thus allowing the observation of multimode lasing with an optical pumping

162 Here we report the observation of multiple absorption lines from an extreme

163 Direct observation of multiple reactive sites in the zeolite HZ

164 this extreme localization of BISER by direct observation of nano-scale coherent x-ray sources in a la

165 findings help explain the range of published observations of Nanog variability and highlight the prob

166 Direct observation of nanoparticles in the early stages of grow

167 145 meV, PLQY ca. 1.8%), which is the first observation of narrow near-infrared fluorescence for cop

168 Based on the observation of natural hydrothermal pyrites, As(-I) is u

169 Given the observations of neuronal hyperactivity in prodromal AD,

170 Rapid-response polarimetric observations of newly discovered bursts have probed the

171 To our knowledge, this is the first observation of non-cyclic-nucleotide small molecules wit

172 crystals not only offer a route towards the observation of non-trivial states, but also open the way

173 ey provide a mechanistic explanation for the observation of nonsynonymous SNPs in fnbA among clinical

174 Non-participant observation of nurse-led chemotherapy clinics, semi-stru

175 Twenty hours of observation of nursing staff's interactions with patient

176 scopy at unprecedented resolution for direct observation of oil droplet deposition, deformation, and

177 ge versus conceptual knowledge modulates the observation of others' actions.

178 Our observation of parallel gene retention and loss across m

179 However, observations of Peltier cooling in molecular junctions-a

180 Here, we report direct experimental observations of Peltier cooling in molecular junctions.

181 On the other hand, macroscopic observations of phase transitions, with millisecond or l

182 mic findings explain and support qualitative observations of phase-transformation patterns gathered f

183 ear-field scanning measurements, we show the observation of photonic topological surface-state arcs c

184 nce was first noted in the past century from observations of planets in our own Solar System and has

185 Direct observations of pMHC:TCR and CD80:CD28 binding events re

186 The observation of pop-in events and slip bands on the surfa

187 These data may be consistent with observations of prominent mitochondrial dysfunction as a

188 Here, we report the observation of quantized conductance in the surface band

189 Here, we report on the observation of quantum Zeno blockade on chip, where a li

190 f their fractal parameters with experimental observations of radiation damage buildup remains elusive

191 Our observation of RAGE inhibition provided novel insight in

192 address the development of a real-time time observation of RBCs agglutination.

193 The solution was validated using field observations of recent earthquakes, where we were able t

194 hopping electron transport occurs, enabling observation of redox processes in real time at the singl

195 The observation of reduced perfusion in the posterior cingul

196 The clinical observation of reduced ROP severity in premature infants

197 tance alleles is the primary explanation for observations of reduced pesticide efficacy over time, bu

198 The methodology was further validated by the observation of reduction in tetracycline accumulation in

199 Observation of remarkable induction of GPR64 expression

200 The observation of replica bands in single-unit-cell FeSe on

201 gion to be retrieved, is appropriate for the observation of rogue waves, which come up as a random ph

202 Combined, this enables observation of root tips growing along the natural gravi

203 However, some observations of scavengers avoiding feeding on carnivore

204 he OCT observations were validated by direct observations of sectioned specimens under confocal laser

205 2014-2015 in Lancaster, we confirm previous observations of seropositivity in the majority of the po

206 The frequent observation of side chains associated with turn motifs a

207 We report the observation of single bottlebrush proteoglycan dynamics

208 The key in the observation of single redox events are the use of a fluo

209 oretical results explain recent experimental observations of single-cell lysis times in bacteriophage

210 te model predictions of Ndep effects against observations of SOC at a regional field scale.

211 Using observations of SOC dynamics with detailed soil properti

212 ore be detectable spectroscopically in X-ray observations of solar analogs.

213 The observations of solar flare onsets show rapid increase o

214 Consistent with previous observations of species-specific regulation of immunity

215 s in transition-metal complexes, enables the observation of spin-allowed emission directly to the gro

216 Both the frequent observation of SSA at an inland site and the range of ch

217 This allowed direct observation of stochastic firing of DNA replication orig

218 omote preferential delithiation, whereas the observation of strain-induced cracking suggests mechanic

219 It started from the observation of strong circular dichroism during the synt

220 Equally surprising was the observation of strong longer-range order in this mixed s

221 iosperm genomes (20 to 70) has prevented the observation of strong phenotypes in loss-of-function mut

222 igh pressure, and so far no one reported the observation of structure phase transition induced by pre

223 This technical advance enabled detailed observation of sub-cellular processes in primary human a

224 The observation of such a time crystal opens the door to the

225 Here we report on the direct observation of such hidden magnetic correlations via qua

226 Here we report the experimental observation of such mid-infrared dispersive waves, embed

227 Recent observations of switching of magnetic domains in ferroma

228 Direct observation of TF assembly and disassembly and various b

229 Here we report the observation of the 1S-2S transition in magnetically trap

230 hase transition in VO2 This technique allows observation of the bulk material in real time, follows t

231 f an IDR that folds upon binding through the observation of the free state of the protein.

232 ium temperatures, respectively, allowing the observation of the fully developed quantum Hall effect.

233 Only one study used direct observation of the healthcare professionals during pract

234 ibology on the nanoscale and has allowed the observation of the hitherto invisible property of phosph

235 n-sedated neonatal patient and (b) where the observation of the impact of respiration on flow is nece

236 activation reaction was too fast for direct observation of the intermediates, but they could be caug

237 iles post-elutriation, as exemplified by the observation of the maturation of a second flagellar basa

238 y imaging technique was employed for in-situ observation of the microstructure evolution during testi

239 ication of the amount of active catalyst and observation of the molecular weight distribution (MWD) o

240 The observation of the multiband emission is possible becaus

241 an instrumental tool, in vivo studies allow observation of the overall effect on a living organism.

242 Moreover, the observation of the parent uncapped {Mo150 } and {Mo120 C

243 The recent experimental observation of the quantum anomalous Hall effect has cas

244 is constitutes the first direct experimental observation of the residence time of Cd(2+) coordinated

245 neutron scattering studies enable the direct observation of the role of amide groups in substrate bin

246 redicted infant motor system activity during observation of the same expressions at nine months.

247 Since the first observation of the spin-valve effect through organic sem

248 the analysis of adsorption isotherms, direct observation of the structural transitions has been lacki

249 on sensitization phenomenon resulting in the observation of the typical green emission of Tb.

250 However, experimental observation of the ultrafast dynamics of this chiral mag

251 Dias and Silvera claim the observation of the Wigner-Huntington transition to metal

252 Liu et al present negative comments on our observation of the Wigner-Huntington transition to metal

253 The visual (observation) of the operation of the LS DESI MS system s

254 re we report an analysis of archival optical observations of the 'non-magnetic' accreting white dwarf

255 The observations of the additive effects of advanced and del

256 Here we report observations of the bright star HD 195689 (also known as

257 Whereas this behaviour is consistent with observations of the closure of microcracks formed parall

258 enetic mechanisms and important new clinical observations of the disease course provide fresh clues a

259 echanism is deemed inadequate to explain the observations of the eddy-covariance systems, which must

260 ncentration-dependent manner, in contrast to observations of the effect of LIS1 on the motility of is

261 etic differentiation correlate with previous observations of the existence of barriers to gene flow A

262 ltaneous infrared, optical, x-ray, and radio observations of the Galactic black hole system V404 Cygn

263 We report on the first observations of the giant deep-sea octopus Haliphron atl

264 entionally introduced insect herbivores, and observations of the impacts of insect species that show

265 Data from participant observations of the intrahospital transport process were

266 The Juno spacecraft acquired direct observations of the jovian magnetosphere and auroral emi

267 Reconciling geophysical observations of the melting regime beneath the East Paci

268 (i.e., 59%-61% median identity), on par with observations of the most distantly related species pairs

269 subionospheric very low frequency radiowave observations of the NAA 24.0 kHz transmitter, Cutler, Ma

270 Here we report observations of the quasar ULAS J134208.10 + 092838.61 (

271 d as a mode for rapid adaptation, but direct observations of the selective benefits and associated me

272 The plasma composition in full-disk observations of the Sun is related to the evolution of c

273 Here we use observations of the turbulent properties of the meltwate

274 One of the most significant observations of the work is the presence of spikes in el

275 nature of these states has precluded direct observation of their properties.

276 -sized clusters and consequently enables the observation of thermodynamically less favored and theref

277 Direct microscopic observation of these phantoms, revealed a significant (p

278 Here we demonstrate the experimental observation of these topological edge modes in a 2D phot

279 The experimental observation of this type of CHpi interaction adds a new

280 uration of the products was confirmed by the observation of through-space (13)C-(19)F couplings, acce

281 Despite the observation of transcription and periodic expression of

282 onal electron microscopy (4D EM) has enabled observation of transient structures and morphologies of

283 A direct observation of transport dynamics in individual CmeB tri

284 apture-recapture approach to model imperfect observations of true epidemiological states.

285 ering it an effective tool for the long-term observation of tumor evolution.

286 Here, we report an in situ atomic-scale observation of twin nucleation in nanocrystalline Pt.

287 C6H3-2,6-(OP((t)Bu)2)2] complexes results in observation of two new iridium-dihydrogen complexes.

288 binding to Sites 1 and 2 is here revealed by observation of UbcH7 approximately ubiquitin-dependent s

289 Here we report the observation of ultrahigh third-order nonlinearity about

290 concentrations ([CO3(2-)]spec) derived from observations of ultraviolet absorbance spectra in lead-e

291 Our observations of understory development from lidar either

292 Observations of uniflagellar bacteria show that buckling

293 This view is supported by the observation of unusual growth of nucleated domains, whic

294 utrient content data were collected from 144 observations of upper canopy leaves from at least 65 spe

295 Data collection included observations of vaccination sessions, interviews with th

296 field of a microwave cavity, as shown by the observation of vacuum Rabi splitting.

297 Direct observation of verbalized laboratory data during daily I

298 Direct and widespread observations of vertical canopy structures that drive ra

299 ge records that both incorporates up-to-date observations of vertical land motion (VLM) and correctio

300 rs and microcores, and coupled these data to observations of water potential, soil moisture, and vapo