ライフサイエンスコーパス: obviate

1 he current requirement for DNA sequencing is obviated.

2 risk of ciTBIs for whom CT can routinely be obviated.

3 sk for enterococcal IE and that TEE could be obviated.

4 This approach could be useful, obviating (18)F-FDG scans when longer-lived amyloid imag

5 Taken together, these results obviate a paradox of selective insulin resistance, becau

6 fusion led to important ecological insights, obviated a commonly ignored type of collinearity, and wa

7 , SL identified 94.1% of the DLs and thereby obviated a nontherapeutic laparotomy in 55.9% of patient

8 cell-autoreactive CD8 T cells in NY8.3 mice obviated a role for CD137 in diabetogenesis.

9 This high contrast obviates a following quantum-limited amplifier.

10 It obviates a separate surgical procedure but requires long

11 r reprogramming factor (RF) expression while obviating a cleanup phase to purge residual traces of ve

12 Loss of Hand2 is embryonic lethal by E9.5, obviating a genetic analysis of its in-vivo function.

13 sive AGXT analysis for the diagnosis of PH1, obviating a liver biopsy in most well-characterized pati

14 inactivating promoter mutation, in contrast, obviates all three.

15 Obviating an external trigger for reactivity and affordi

16 The strategy used in this study would obviate any potential concerns regarding the use of MIP

17 llaborate, desensitize Hsp104 to inhibition, obviate any requirement for Hsp70, and enhance ATPase, t

18 ionally, a TS (CDC21) knockout yeast strain, obviating any potential role for TS protein as a target,

19 apacity sterol transport and esterification, obviating any requirement for soluble intermediary prote

20 -care testing method for GAS pharyngitis and obviate backup testing on negative results.

21 ucturally modified superhydrophobic surfaces obviate bacterial resistance common with chemical agents

22 to arrive at an early diagnosis and also to obviate biopsy in cases with classical imaging findings.

23 This obviates both the need for a time zero spectrum as well

24 The iMAP simultaneously obviates both the O1 and O6 protection, and the differen

25 , and nonadherence; these limitations may be obviated by a sustained release formulation.

26 induction of brain death-a decline that was obviated by administration of ethyl nitrite.

27 ement for the constrained beta-turn motif is obviated by alkylation of a cysteine residue with a Sox-

28 le the overt consequences of Mcl-1 loss were obviated by combining with the loss of Bax and Bak, mito

29 induction of this tolerant state by ECP was obviated by cotreatment with lipopolysaccharide, suggest

30 n conventional sorbent-based extraction, was obviated by dissolving the sorbent in acid after extract

31 ere, we demonstrate that assumption I can be obviated by equilibrating a silicone sampler with chemic

32 bacterial agonists, and this suppression was obviated by IL-10-specific antibody.

33 benefit in men, and this benefit may now be obviated by improved medical treatment.

34 rboxamide bis(diazaphospholane) ligands that obviates chromatographic purification is presented.

35 cannot be used by Pseudomonas aeruginosa to obviate coaBC.

36 hylene diamine tetraacetic acid treatment to obviate complement interference.

37 sks, to alter the natural history of DCM and obviate complications such as HF/arrhythmias.

38 Here, unadulterated samples obviate concerns about downstream purity and also exhibi

39 ic means to justify l-thyroxine monotherapy, obviating concerns about inconsistencies with desiccated

40 The data added by 3D ultrasound may obviate confirmatory testing with magnetic resonance ang

41 s are under way to determine whether PET can obviate consolidation radiotherapy in patients with diff

42 was chosen because its high fibrin affinity obviates continuous infusion of this thrombolytic agent.

43 This approach obviates conventional relative quantification using an i

44 th can be used in paraffin sections, thereby obviating cumbersome oil red O staining of frozen sectio

45 the system provides multi-user support that obviates current practices of sharing data sets as files

46 CT urography in patients with hematuria may obviate cystoscopy in selected patients.

47 placement strategy overcomes this problem by obviating direct labeling of the target DNA.

48 for the determination of As, Hg and Pb that obviate dissolution and mineralization.

49 ore ratios are measureable through the skin, obviating drawbacks of dual sugar absorption tests.

50 is, application of the NOVA score may safely obviate echocardiography in 14%-27% of patients with E-B

51 and diet-induced obesity mice, suggesting CR obviates epigenetic alterations concurrent with chronic

52 in the future, RDTR/SCF-LVs might completely obviate ex vivo handling and simplify gene therapy for m

53 the absence of rigorous temperature control, obviates extended detector equilibration wait times.

54 ents with unexplained clubbing might help to obviate extensive searches for occult pathology.

55 of patients with a clinical diagnosis of SVT obviates extensive imaging and laboratory workup and may

56 Our procedure obviates extraction into organic solvents, postreaction

57 that were attributed to the tinnitus, which obviates further tinnitus-specific intervention.

58 of the consensus SUMOylation site, Lys(447), obviated Hsp27-mediated F508del NBD1 SUMOylation and deg

59 rapy represents an autologous transplant, it obviates immune suppression before and after transplant,

60 oped a simple peptide vaccine construct that obviates immunodominance, resulting in a broadly protect

61 ys that restrict their explanatory power and obviate important subtleties.

62 Protease inhibitor therapy could be obviated in genotype 1-infected treatment-naive patients

63 libration curves for all strong acid anions, obviating individual calibrations.

64 fforded by electronically active systems and obviating issues with chronic implants.

65 ion reduces the required amount 100-fold and obviates its dependence on TLR signaling.

66 wer pK(a) of the selenol relative to a thiol obviates its need to be protonated upon S-Se bond scissi

67 and a signal enhancement of 4 x 10(3), thus obviating key constraints in semiconductor strain metrol

68 y environment, however electronic cigarettes obviate many of these issues, and provide a close simula

69 ver, nuclear PRMT1 was not stable postmortem obviating meaningful evaluation of ALS autopsy cases.

70 Knockdown of AMPD obviated metformin stimulation of glucose transport.

71 g process-labile TT in PLGA was found to: a) obviate micronization- and organic solvent-induced TT de

72 damage, reverse membrane depolarization, and obviate mitophagy.

73 iple be linked to virtually any surface, and obviate monitoring deformations of elastic substrates.

74 The SGS protocol obviated most molecular steps in conventional methods an

75 creased awareness of this broad spectrum may obviate need for biopsy in many circumstances, an import

76 ivery of a synthetic tumor suppressor mimic, obviating obstacles associated with viral-based miRNA de

77 geted T cells modified to secrete IL-12 will obviate or reduce the need for potentially hazardous con

78 lar BCC or basal cell nevus syndrome and can obviate orbital exenteration in some patients.

79 as by real-time PCR and, by pooling samples, obviated over 50% of reactions and halved the cost of te

80 ation of MM and if selectively inhibited may obviate progression and relapse.

81 The ability to obviate radical transport by disrupting the hydrogen bon

82 device infection before catheter removal may obviate removal of a substantial number of devices.

83 nsequent minimization of toxicity, and could obviate repeated drug administrations or device implanta

84 Coronal-load implants obviate resident bone remodeling without compromising lo

85 s and BCR-ABL may eliminate dormant LSCs and obviate resistance.

86 Such a proposal would not obviate rights under the IQA to obtain raw data at a lat

87 marrow composition and hemodynamics in vitro obviates risks associated with platelet procurement and

88 ated; thus, the problem of aberration can be obviated simply by selecting a chip material that matche

89 vide a direct measure of gene expression, it obviates some of the limitations associated with other g

90 llogeneic CDCs, if safe and effective, would obviate such limitations.

91 If supported by further research, CBVT may obviate surgical reentry as a technique for assessing re

92 edforward FGFR1-ETS2 angiocrine cascade that obviates TEC IGFBP7.

93 es how experimentally observed filopodia can obviate the classical Euler buckling condition and remai

94 enable single dose delivery, and potentially obviate the cold chain.

95 crystal structures identified strategies to obviate the DDI liability, leading to compound 16, which

96 r induced illness and their management might obviate the development of this disorder.

97 on, using horizontal saccadic latencies that obviate the impact of limb slowness on executing respons

98 on of aryl carbon-hydrogen (C-H) bonds would obviate the inefficiencies associated with generating ha

99 st disease morbidity and mortality which may obviate the long-term benefit.

100 promising approach is the use of agents that obviate the mutation.

101 To obviate the necessity and complexity of conjugating two

102 This is sufficient to obviate the need for amplification in many cases.

103 tests, the absence of any positive test can obviate the need for antifungal agents with a negative p

104 Deformation-tracking could potentially obviate the need for bespoke strain sequences, reducing

105 latable, belatacept-based regimen that could obviate the need for both CNIs and steroids.

106 bleeding has a good prognosis and can often obviate the need for DBE, a currently limited resource.

107 -energy coronary CT angiographic studies may obviate the need for dedicated CT calcium scoring studie

108 m transplantation, or does achievement of CR obviate the need for front-line transplantation altogeth

109 a critical p53-independent function and may obviate the need for genomic alterations to the p53 path

110 As such, our results obviate the need for hidden-reservoir or super-chondriti

111 iently low-risk subset in this population to obviate the need for ICD implantation.

112 g organogenesis [embryonic day 28 (E28)] can obviate the need for immune suppression in rats or rhesu

113 transplanting them in a durable device could obviate the need for immunosuppression, while also prote

114 A 'pro re nata' (PRN) injection protocol may obviate the need for intervention.

115 patients with leptomeningeal metastasis and obviate the need for intra-CSF chemotherapy.

116 patients with leptomeningeal metastasis and obviate the need for intra-CSF chemotherapy.

117 ethods to induce donor-specific tolerance to obviate the need for life-long immunosuppression that is

118 These new treatments do not obviate the need for lifestyle and dietary management, a

119 ted or decompensated cirrhosis, and delay or obviate the need for liver transplantation in some patie

120 ring treatment of ovarian cancer as it would obviate the need for more invasive surgical biopsies.

121 eneficial for perioperative pain and perhaps obviate the need for oral narcotics.

122 generative medicine and disease modeling and obviate the need for protocols based on stromal feeders

123 nd potential treatments for TED patients and obviate the need for reconstructive surgical therapies.

124 Oral iron chelation may obviate the need for red cell exchange as a means to pre

125 with a failed surgical bioprosthesis and may obviate the need for reoperation.

126 ly controllable, resorbable devices not only obviate the need for secondary surgeries and retrieval,

127 led cortical-sparing adrenalectomy which may obviate the need for steroid hormone replacement in pati

128 on (AR) in heart transplant recipients could obviate the need for surveillance endomyocardial biopsie

129 inical, physiological, and radiological data obviate the need for the increased risk associated with

130 me imaging and no ionizing radiation and may obviate the need for the patient to schedule additional

131 ith targeted therapies or immune therapy may obviate the need for WBRT; prospective studies are requi

132 pectral AP alternans during sinus rhythm may obviate the need to actually demonstrate AF, such as on

133 at the expense of increased mutagenesis, and obviate the need to resolve stalled/collapsed forks by p

134 We show that eIF5A can obviate the polyamine requirement for general translatio

135 Suppressor mutations were isolated that obviate the requirement for essential PBP2b in periphera

136 on to a highly expressed endogenous gene may obviate the requirement for nucleases and/or vector-born

137 Spy1 confers structural changes to Cdk2 that obviate the requirement of Cdk activation loop phosphory

138 The reduction of the systemic dose may obviate the side effects.

139 se results highlight the ability of IL-12 to obviate the strict requirement for administering high le

140 Spherulites obviate the substantial experimental complexities that a

141 ful application of several key concepts that obviate the well-known disadvantages of SnTe.

142 phatidylinositol 3-kinase inhibitor LY294002 obviated the ability to sense substrate stiffness, sugge

143 etion of p53 at the time of tumor initiation obviated the acquisition of later deletions, establishin

144 inal assessments of the same individuals, we obviated the many sources of variation in brain structur

145 Provision of exogenous IL-2 obviated the need for conventional CD4(+) T cells in the

146 This composition obviated the need for external energy sources and allowe

147 opments in clinical practice have reduced or obviated the need for muscle relaxants in pediatric anes

148 Therapy with DA-EPOCH-R obviated the need for radiotherapy in patients with prim

149 catalytically inactive ternary complexes and obviated the need for using 2',3'-dideoxy-terminated oli

150 ined using nanomolar concentrations of BARAC obviated the need for washing steps.

151 ent transitions to holocentricity in insects obviated the need to maintain CenH3, which is otherwise

152 on of Mycobacterium tuberculosis in vivo, we obviated the requirement for antimicrobial immunity and

153 Our approach obviates the choice of the lasso parameter by imposing a

154 PCA obviates the customary focus on specific peaks or region

155 Importantly, in situ DNase Hi-C obviates the dependence on a restriction enzyme to diges

156 The stepwise mechanism obviates the electronic requirement inherent to a concer

157 This mechanism elicits tumorigenesis and obviates the growth-inhibitory effects of TGF-beta.

158 work as a first-pass screening device which obviates the necessity of multiple and wasteful specimen

159 -duck/egg system can be scaled as needed and obviates the necessity of using limited blood products o

160 Such a mechanism obviates the need for a decarboxylase and is consistent

161 subducted atmospheric Xe and MORB Xe, which obviates the need for a less degassed deep-mantle reserv

162 This approach obviates the need for a secondary screen to avoid cytoto

163 nduced mechanism of disulfide bond formation obviates the need for a thiol/disulfide oxidoreductase i

164 The latter characteristic obviates the need for an extra framed holder for rapid T

165 ar biosynthesis of spin-labeled proteins and obviates the need for any chemical labeling step usually

166 The method obviates the need for any high frequency RF components a

167 This new approach obviates the need for approximations that must be made i

168 Likewise, this unified approach obviates the need for both electron spin resonance manip

169 cross plates in a plate-wise analysis, which obviates the need for choosing either a plate-wise or ex

170 erently high cross-selectivity of the system obviates the need for directing groups or a large excess

171 introduce heritable mutations into a genome obviates the need for embryonic stem cell lines and shou

172 h the CO and an active catalyst, and thereby obviates the need for handling a toxic gas.

173 The use of the tailed primers obviates the need for hapten labelling and consequent us

174 d (ii) a one-step (18)F-labeling method that obviates the need for HPLC purification.

175 This dominant transgenic approach obviates the need for incorporating recessive lpa1 mutat

176 VAMPS obviates the need for individual research groups to make

177 stick monitoring, a higher HbA1c target that obviates the need for insulin may be appropriate.

178 tteries because, unlike elemental sulfur, it obviates the need for metallic lithium anodes.

179 This methodology obviates the need for minimal growth media, specialized

180 Here we present a sensor design that obviates the need for optical addressability by operatin

181 sation steps proceeds under mild conditions, obviates the need for oxidants, releases N2 and H2O as t

182 ty and consumer-resource oscillations, which obviates the need for parameterizing complex dynamical m

183 The method we employ obviates the need for permanent implants and could poten

184 and STORM for studies of Ca2+ channels as it obviates the need for photoswitchable labels and provide

185 tion, and the absence of host immunity often obviates the need for preconditioning.

186 ly a single sample is required, the approach obviates the need for preparing multiple samples and eli

187 le, low-dispersion electrophoretic transport obviates the need for pumps and valves.

188 The impact of ethnicity is minimal, which obviates the need for race-specific RV reference values.

189 strategy that improves the rate of cure and obviates the need for radiotherapy.

190 amplification of desired sequences and that obviates the need for solid-phase capture, washing, and

191 The CS linkage probably obviates the need for strong interactions between b(5) a

192 This approach obviates the need for the classical N-protection/O-activ

193 This efficient inline injection system obviates the need for the excess sample that is required

194 This process obviates the need for the harsh deprotection conditions

195 otein, not merely highly conserved ones, and obviates the need for the time consuming, expensive, and

196 Our approach obviates the need for transcript annotations and circumv

197 topic stimulation of this signalling cascade obviates the need for tuft cells in the epithelial cell

198 ell is potentially more efficient because it obviates the need for two separate cell lines and purifi

199 ability of these simple complementary assays obviates the need for undesirable radiotracer-based assa

200 finding is that the presence of acetonitrile obviates the need for using excess amounts of a more val

201 kylation or alkenylation reactions, and thus obviates the need to access 1,4-dicarbonyl compounds via

202 uctor (SS-OPV) offers several advantages: it obviates the need to control the highly system-dependent

203 algorithm that predicts the Mn/M0 ratios and obviates the need to determine the intensity of all of t

204 blishes the chirality of the tertiary azide, obviates the need to directly forge either a congested C

205 f a photolabile group on the amine precursor obviates the need to employ a photoredox catalyst in thi

206 nomical strategy used by the cell because it obviates the need to further deplete cellular iron level

207 effect helps overcome these limitations and obviates the need to make hard x-ray absorption gratings

208 res, 4- and 6-azaindoles and thienopyrroles, obviates the need to prepare potentially toxic aryl hydr

209 This strategy obviates the need to regulate multiple genes and decreas

210 how PG synthesis might drive engulfment, and obviates the need to synthesize a PG layer de novo durin

211 This convenient method obviates the need to use highly reactive agents for chem

212 This protocol obviates the purification techniques such as column chro

213 tation of either the c-Src SH2 or SH3 domain obviates the RANK/alphavbeta3 association.

214 ditions of stress by resisting apoptosis and obviates the requirement for serum or a feeder layer for

215 Finally, N obviates the requirement for the helicase, eIF4A.

216 repare N(2)-acyl analogues in a fashion that obviates the troublesome acylation of the free 2-aminoim

217 Isothermal amplification, on the other hand, obviates the use of a thermal cycler because reactions o

218 linked enzyme coatings on intact CNTs, while obviating the chemical pretreatment that can seriously d

219 Merely obviating the condition of solution averaging wholly cha

220 ient-specific performance rates is illusory, obviating the ethical obligation to communicate them as

221 eered dissipation to counteract decoherence, obviating the need for a complicated external feedback l

222 ate transient site for sulfur transfer, thus obviating the need for a rhodanese domain.

223 tly into existing biological databases, thus obviating the need for a user to search in multiple loca

224 nor T-cell-replete bone marrow allografting, obviating the need for additional prophylactic immunosup

225 alized patients with a label of PenA thereby obviating the need for allergy tests.

226 anges the turnover limiting transition step, obviating the need for an added cocatalyst.

227 consequently decreasing the risk of SCD and obviating the need for an ICD.

228 center to which they are both bound, thereby obviating the need for an integral change in metal redox

229 l pandemic influenza virus strains therefore obviating the need for annual vaccination, and enhancing

230 d for both the cystic duct and artery, thus, obviating the need for any transabdominally placed instr

231 in signals are large (1-20% above baseline), obviating the need for averaging.

232 tracellular loops to some degree, apparently obviating the need for Ca(2+).

233 the success of persistent AF ablation while obviating the need for chronic anticoagulation.

234 em for its sustained local delivery in vivo, obviating the need for chronically implanted catheters a

235 a correctly assembled product in vivo, often obviating the need for clonal isolation.

236 to benefit from simple cataract extraction, obviating the need for combined cataract and glaucoma su

237 rom a graphite electrode is described herein obviating the need for defect inducing oxidative or prol

238 slightly inhibited FEN1 cleavage, apparently obviating the need for Dna2.

239 ssemble genes across distantly-related taxa, obviating the need for draft genome assembly of all taxa

240 at temperatures between 5 and 22 degrees C, obviating the need for ethylene glycol.

241 ers use a self-contained actuation response, obviating the need for external tethers in operation.

242 es that could eliminate allograft rejection, obviating the need for immunosuppression.

243 ephalosporin with a short half-life, thereby obviating the need for increasingly challenging SAP timi

244 application through the intact human skull, obviating the need for invasive and risky surgical proce

245 actic-co-glycolic acid) (PLGA) microspheres, obviating the need for invasive intrathecal pumps or cat

246 stic modality for congenital heart diseases, obviating the need for invasive modalities.

247 on of highly contiguous physical genome maps obviating the need for labor-intensive physical genome m

248 fractionated lysates (72 hr analysis) while obviating the need for peptide detection prior to quanti

249 onsible for object recognition, in this case obviating the need for PPC contributions and expanding P

250 apted to a capillary electrophoresis format, obviating the need for radiolabeled probes and allowing

251 ntly remove water from the reaction mixture, obviating the need for rigorously dry solvents.

252 lic gene disruption at frequencies >1%, thus obviating the need for selection markers.

253 tocol is characterized by a wide scope while obviating the need for sensitive organometallic species

254 table ammonia surrogate (alpha-amino acids), obviating the need for special experimental setup or han

255 emperature, and ionic strength used, thereby obviating the need for spectral calibration with interna

256 educing concerns about reagent stability and obviating the need for storage of solutions of the highl

257 ariables as predictors of TOC concentration, obviating the need for streamflow.

258 or the treatment of large colorectal polyps, obviating the need for surgery in most instances.

259 were absent from the locus in NOD Th0 cells, obviating the need for Th1 differentiation signals to es

260 ic stabilization from global delocalization, obviating the need for the concept of superaromaticity.

261 bility can be incorporated into the analysis obviating the need for the ubiquitous assumption that th

262 used to efficiently count transcripts while obviating the need for transcript-length normalization a

263 tical to parameters derived from blood, thus obviating the need for venous sampling in these patients

264 ures all genes are derepressed at once, thus obviating the need for VP16 to initiate sequential derep

265 m of the simultaneously active conductances, obviating the need for weak coupling assumptions.

266 compared with conventional 2-tiered testing, obviating the need for Western blots.

267 ectron temperatures in other nanostructures, obviating the need to adapt traditional, large demagneti

268 inimized in a cobalt porphyrin-based system, obviating the need to employ excess substrates and slow

269 rect access to a large minefield area, while obviating the need to endanger personnel and equipment.

270 d from the perspective of inclusive fitness, obviating the need to evoke group selection as a contrib

271 as a diffuse interface on this mesh, thereby obviating the need to explicitly track the (potentially

272 much more rapid analysis of gene function by obviating the need to initially establish stably transfo

273 eates the well-known crossover paradox, thus obviating the need to posit common causes of early birth

274 livering the data in a simple parsed format, obviating the need to post-process the alignment results

275 alcohol is oxidized in situ to an aldehyde, obviating the need to prepare sensitive keto aldehyde su

276 By obviating the plasma staining that results from aqueous

277 d mRNA, allows rapid screens (<4 h), thereby obviating the potential toxicity of splicing inhibitors.

278 and contains no meat or dairy products, thus obviating the problem of possible prion diseases.

279 ected with different HIV-1 subtypes, thereby obviating the requirement for HIV-specific immunity.

280 tients with OUD, with the further benefit of obviating the risk for misuse and diversion of daily bup

281 n system, while, under the consideration for obviating the risk of mutagenic insertion and enables mo

282 d differentiation to multiple lineages while obviating the stringent needs for complex, exogenous mat

283 HC borane serves as the hydrogen donor, thus obviating the use of tin-based reagents.

284 ased upon a subtle change to the imine, thus obviating the usual requirement for both the trans- and

285 ies targeting aberrant properties of LSC may obviate therapeutic resistance and relapse in advanced p

286 Two-dimensional materials such as graphene obviate these issues and offer a new paradigm for tunnel

287 To obviate these limitations, we have developed an open-sou

288 id, and inexpensive to use in the office may obviate these problems.

289 e a unique strategy for dimer formation that obviates these difficulties, one which rapidly construct

290 to phenylalanine to prevent phosphorylation obviates these effects.

291 dern computed tomography (CT) technology may obviate this and allow for immediate clearance.

292 ypes of ON cone bipolar cells and AIIs would obviate this high-sensitivity pathway and explain the ex

293 To obviate this problem, in this study we generated a human

294 To obviate this problem, silica nanoshells were tested for

295 To obviate this problem, we report here the use of a sensit

296 cellular degradation pathways is relevant to obviate toxic mHtt species and subsequent neurodegenerat

297 ural thickness and shrinking lung, and might obviate unnecessary invasive procedures for MPM.

298 factors that predict disease progression may obviate unnecessary morbidity associated with regional t

299 tiparametric MR imaging may have potentially obviated unnecessary breast biopsies in six of eight les

300 cellular carcinoma (HCC) patients, to try to obviate upfront liver transplantation, with the "safety