ライフサイエンスコーパス: obviate the need for

1 lmonologist or radiologist are sufficient to obviate the need for a lung biopsy.

2 Chimeric G-protein-coupled receptors obviate the need for a particular agonist ligand when th

3 PrPSc, variant CJD could be diagnosed, which obviates the need for a brain biopsy sample to be taken.

4 Such a mechanism obviates the need for a decarboxylase and is consistent

5 ly applicable positional cloning method that obviates the need for a genetic map.

6 This technical modification obviates the need for a left hepatic artery microvascula

7 subducted atmospheric Xe and MORB Xe, which obviates the need for a less degassed deep-mantle reserv

8 ) T cells; the rapid deletion of these cells obviates the need for a regulatory cell population to su

9 This approach obviates the need for a secondary screen to avoid cytoto

10 t sensory-to-motor coordinate transformation obviates the need for a single representation of space i

11 nduced mechanism of disulfide bond formation obviates the need for a thiol/disulfide oxidoreductase i

12 This obviates the need for a time consuming post-reaction wor

13 that rapid transport through the lipid phase obviates the need for a transport protein.

14 eered dissipation to counteract decoherence, obviating the need for a complicated external feedback l

15 extended structure acting as a built-in lid, obviating the need for a GroES-like co-factor.

16 ate transient site for sulfur transfer, thus obviating the need for a rhodanese domain.

17 with translation termination for UAG codons obviating the need for a specific PYLIS structure.

18 tly into existing biological databases, thus obviating the need for a user to search in multiple loca

19 s the reduction of ambient O(2) to water and obviates the need for adding H(2)O(2).

20 dominant T cell epitopes within proteins may obviate the need for additional subdominant epitope modi

21 lp avoid overdiagnosis in this group and can obviate the need for additional unwarranted computed tom

22 agnosis, thereby guiding optimal therapy and obviating the need for additional costly and potentially

23 nor T-cell-replete bone marrow allografting, obviating the need for additional prophylactic immunosup

24 n of the vascular converting enzyme does not obviate the need for aldosterone receptor blockade in pa

25 alized patients with a label of PenA thereby obviating the need for allergy tests.

26 This is sufficient to obviate the need for amplification in many cases.

27 Although BV pacing does not obviate the need for an ICD, it does diminish the need f

28 equally cost-effective as arteriography and obviates the need for an arteriogram in many patients.

29 The latter characteristic obviates the need for an extra framed holder for rapid T

30 anges the turnover limiting transition step, obviating the need for an added cocatalyst.

31 consequently decreasing the risk of SCD and obviating the need for an ICD.

32 center to which they are both bound, thereby obviating the need for an integral change in metal redox

33 lation of chloroplast transcription, thereby obviating the need for an organellar clock, at least for

34 l pandemic influenza virus strains therefore obviating the need for annual vaccination, and enhancing

35 patients with ischemic heart disease and may obviate the need for antianginal medications.

36 tests, the absence of any positive test can obviate the need for antifungal agents with a negative p

37 ar biosynthesis of spin-labeled proteins and obviates the need for any chemical labeling step usually

38 The method obviates the need for any high frequency RF components a

39 d for both the cystic duct and artery, thus, obviating the need for any transabdominally placed instr

40 This new approach obviates the need for approximations that must be made i

41 A negative SPECT study may obviate the need for arteriography.

42 in signals are large (1-20% above baseline), obviating the need for averaging.

43 l better approximate true disease status and obviate the need for backup cultures if specificity can

44 Deformation-tracking could potentially obviate the need for bespoke strain sequences, reducing

45 teine without the amino acid moiety, thereby obviating the need for beta-lyase action.

46 latable, belatacept-based regimen that could obviate the need for both CNIs and steroids.

47 Likewise, this unified approach obviates the need for both electron spin resonance manip

48 ally invasive diagnostic procedures that may obviate the need for brain biopsy in the future.

49 tracellular loops to some degree, apparently obviating the need for Ca(2+).

50 umor regressed from an atrial location, thus obviating the need for cardiopulmonary bypass.

51 sulating surfaces to build up excess charge, obviating the need for charge compensation.

52 cross plates in a plate-wise analysis, which obviates the need for choosing either a plate-wise or ex

53 the success of persistent AF ablation while obviating the need for chronic anticoagulation.

54 g donor-specific organ graft tolerance while obviating the need for chronic immunosuppression.

55 em for its sustained local delivery in vivo, obviating the need for chronically implanted catheters a

56 a correctly assembled product in vivo, often obviating the need for clonal isolation.

57 to benefit from simple cataract extraction, obviating the need for combined cataract and glaucoma su

58 Provision of exogenous IL-2 obviated the need for conventional CD4(+) T cells in the

59 hat naturally occurring capsid substitutions obviate the need for CypA.

60 bleeding has a good prognosis and can often obviate the need for DBE, a currently limited resource.

61 -energy coronary CT angiographic studies may obviate the need for dedicated CT calcium scoring studie

62 rom a graphite electrode is described herein obviating the need for defect inducing oxidative or prol

63 In particular, our formulation obviates the need for defining a cluster "prototype," do

64 ions in liver transplant recipients and thus obviate the need for diagnostic brain biopsies.

65 erently high cross-selectivity of the system obviates the need for directing groups or a large excess

66 slightly inhibited FEN1 cleavage, apparently obviating the need for Dna2.

67 ssemble genes across distantly-related taxa, obviating the need for draft genome assembly of all taxa

68 allel, noncontact electroluminescent readout obviates the need for electrically isolating individual

69 introduce heritable mutations into a genome obviates the need for embryonic stem cell lines and shou

70 cardiac allograft rejection in humans might obviate the need for endomyocardial biopsy as well as im

71 at temperatures between 5 and 22 degrees C, obviating the need for ethylene glycol.

72 of an inducible complementation system that obviates the need for exogenous d-alanine administration

73 fferent sign-of-contrast situations, thereby obviating the need for explicit junction detectors.

74 Awareness of this may obviate the need for extensive medical evaluations.

75 e speed of targeting vector construction and obviates the need for extensive backcrossing to the C57B

76 This composition obviated the need for external energy sources and allowe

77 ers use a self-contained actuation response, obviating the need for external tethers in operation.

78 generated by each factor alone are additive, obviating the need for feedback loops.

79 m transplantation, or does achievement of CR obviate the need for front-line transplantation altogeth

80 To obviate the need for full sampling of protein configurat

81 Dilution of the lysate may obviate the need for further DNA purification.

82 nsive anatomic and physiologic data that may obviate the need for further invasive studies.

83 DNA allows 100% recombinant virus formation, obviates the need for further virus purification and off

84 a critical p53-independent function and may obviate the need for genomic alterations to the p53 path

85 h the CO and an active catalyst, and thereby obviates the need for handling a toxic gas.

86 The use of the tailed primers obviates the need for hapten labelling and consequent us

87 As such, our results obviate the need for hidden-reservoir or super-chondriti

88 ed with each alone (68% to 70%), potentially obviating the need for histologic confirmation when both

89 d (ii) a one-step (18)F-labeling method that obviates the need for HPLC purification.

90 iently low-risk subset in this population to obviate the need for ICD implantation.

91 g organogenesis [embryonic day 28 (E28)] can obviate the need for immune suppression in rats or rhesu

92 transplanting them in a durable device could obviate the need for immunosuppression, while also prote

93 es that could eliminate allograft rejection, obviating the need for immunosuppression.

94 trabodies by direct genetic selection, which obviates the need for in vitro production of antigen for

95 This dominant transgenic approach obviates the need for incorporating recessive lpa1 mutat

96 ephalosporin with a short half-life, thereby obviating the need for increasingly challenging SAP timi

97 VAMPS obviates the need for individual research groups to make

98 A reversible MTHFR reaction would obviate the need for inhibition by S-adenosylmethionine

99 This method obviates the need for inserting an esophageal catheter a

100 stick monitoring, a higher HbA1c target that obviates the need for insulin may be appropriate.

101 A 'pro re nata' (PRN) injection protocol may obviate the need for intervention.

102 therapy may benefit patients with NM and may obviate the need for intra-CSF chemotherapy.

103 patients with leptomeningeal metastasis and obviate the need for intra-CSF chemotherapy.

104 patients with leptomeningeal metastasis and obviate the need for intra-CSF chemotherapy.

105 Radioguided excision may obviate the need for intraoperative frozen section becau

106 pattern of calcification or ossification may obviate the need for invasive biopsy.

107 application through the intact human skull, obviating the need for invasive and risky surgical proce

108 actic-co-glycolic acid) (PLGA) microspheres, obviating the need for invasive intrathecal pumps or cat

109 stic modality for congenital heart diseases, obviating the need for invasive modalities.

110 k relied on a gene's nucleotide composition, obviated the need for knowledge of codon boundaries and

111 elies on a gene's nucleotide composition and obviates the need for knowledge of codon boundaries.

112 on of highly contiguous physical genome maps obviating the need for labor-intensive physical genome m

113 and proteins from stainless steel surfaces, obviating the need for laborious further purification an

114 ethods to induce donor-specific tolerance to obviate the need for life-long immunosuppression that is

115 These new treatments do not obviate the need for lifestyle and dietary management, a

116 This cloning by genetic recombination obviates the need for ligations or bacterial manipulatio

117 vely monitors in vivo N metabolism and might obviate the need for liver biopsy to measure enzyme acti

118 ted or decompensated cirrhosis, and delay or obviate the need for liver transplantation in some patie

119 Reconstruction obviates the need for long-term anticoagulation, and thu

120 ition, deflection of the nerve fiber pathway obviates the need for major blood vessels to bend or kin

121 ful and rapid route to create knockout mice, obviating the need for matings to obtain germ-line chime

122 t in gas sensor design and development as it obviates the need for membrane calibration and should si

123 tteries because, unlike elemental sulfur, it obviates the need for metallic lithium anodes.

124 use model of Down syndrome, these clones can obviate the need for metaphase analyses.

125 either anergy testing nor tuberculin testing obviates the need for microbiologic evaluation when ther

126 This methodology obviates the need for minimal growth media, specialized

127 ring treatment of ovarian cancer as it would obviate the need for more invasive surgical biopsies.

128 hematopoietic repopulating cells, which may obviate the need for multicopy integration to achieve hi

129 This device should obviate the need for multiple coils or surgical interven

130 Because the cost of an SRS is $1800 and may obviate the need for multiple other topographic studies

131 opments in clinical practice have reduced or obviated the need for muscle relaxants in pediatric anes

132 Here we present a sensor design that obviates the need for optical addressability by operatin

133 not be construed as a perfect mechanism that obviates the need for optimal nutritional care of pregna

134 eneficial for perioperative pain and perhaps obviate the need for oral narcotics.

135 ance for nonresectability (100% correct) may obviate the need for other diagnostic modalities or expl

136 sation steps proceeds under mild conditions, obviates the need for oxidants, releases N2 and H2O as t

137 e to PlcR in a translational fusion, thereby obviating the need for PapR secretion, extracellular pro

138 ty and consumer-resource oscillations, which obviates the need for parameterizing complex dynamical m

139 astomosed to the common carotid artery, this obviates the need for patch closure.

140 fractionated lysates (72 hr analysis) while obviating the need for peptide detection prior to quanti

141 monitoring and echocardiographic testing may obviate the need for performing costly EMBs during OKT3

142 The method we employ obviates the need for permanent implants and could poten

143 The use of such small focused libraries obviates the need for phage affinity selection approache

144 This approach to intrabodies obviates the need for phage antibody libraries, avoids t

145 and STORM for studies of Ca2+ channels as it obviates the need for photoswitchable labels and provide

146 The use of a large caliber (16 mm) stent obviated the need for postoperative anticoagulation.

147 onsible for object recognition, in this case obviating the need for PPC contributions and expanding P

148 profound suppression of intimal thickening, obviating the need for precise size matching with the gr

149 tion, and the absence of host immunity often obviates the need for preconditioning.

150 ly a single sample is required, the approach obviates the need for preparing multiple samples and eli

151 generative medicine and disease modeling and obviate the need for protocols based on stromal feeders

152 le, low-dispersion electrophoretic transport obviates the need for pumps and valves.

153 supernatants, with full biological activity, obviating the need for purification or laborious membran

154 The impact of ethnicity is minimal, which obviates the need for race-specific RV reference values.

155 apted to a capillary electrophoresis format, obviating the need for radiolabeled probes and allowing

156 Therapy with DA-EPOCH-R obviated the need for radiotherapy in patients with prim

157 strategy that improves the rate of cure and obviates the need for radiotherapy.

158 e a profound effect on T cell activation and obviates the need for receptor oligomerization.

159 as 4-GU-DANA prevents the attachment itself, obviating the need for receptor cleavage.

160 nd potential treatments for TED patients and obviate the need for reconstructive surgical therapies.

161 Oral iron chelation may obviate the need for red cell exchange as a means to pre

162 on of donor-reactive T cells, precluding and obviating the need for regulatory mechanisms in the main

163 with a failed surgical bioprosthesis and may obviate the need for reoperation.

164 during human preimplantation development and obviate the need for research on the human embryos thems

165 mbda) Red-mediated homologous recombination, obviating the need for restriction enzymes and DNA ligas

166 gap repair using this recombination system, obviating the need for restriction enzymes or DNA ligase

167 ediately after liver transplantation and may obviate the need for retransplantation.

168 d effectively control refractory SVT and may obviate the need for RFA in children <1 year.

169 ntly remove water from the reaction mixture, obviating the need for rigorously dry solvents.

170 Since the assay obviates the need for RNA isolation and is performed in

171 undergoing primary complete repair, and may obviate the need for routine diagnostic catheterization.

172 patients with advanced heart failure and may obviate the need for routine right heart catheterization

173 Thin chambers obviate the need for sample dilution and increase sensit

174 ly controllable, resorbable devices not only obviate the need for secondary surgeries and retrieval,

175 lic gene disruption at frequencies >1%, thus obviating the need for selection markers.

176 tocol is characterized by a wide scope while obviating the need for sensitive organometallic species

177 g both CT and PET images in the same scanner obviates the need for software registration and routinel

178 amplification of desired sequences and that obviates the need for solid-phase capture, washing, and

179 different stages of development of the cell, obviating the need for sorting signals for proper packag

180 ify sources of variability among studies, or obviate the need for sound, compassionate clinical reaso

181 table ammonia surrogate (alpha-amino acids), obviating the need for special experimental setup or han

182 The new fabrication method obviates the need for specialized replication equipment

183 emperature, and ionic strength used, thereby obviating the need for spectral calibration with interna

184 led cortical-sparing adrenalectomy which may obviate the need for steroid hormone replacement in pati

185 educing concerns about reagent stability and obviating the need for storage of solutions of the highl

186 ariables as predictors of TOC concentration, obviating the need for streamflow.

187 The CS linkage probably obviates the need for strong interactions between b(5) a

188 In most patients, low CAC scores appear to obviate the need for subsequent noninvasive testing.

189 RI is greater than mammography, MRI does not obviate the need for subsequent tissue sampling in this

190 significantly higher fascial closure rates, obviating the need for subsequent hernia repair in most

191 or the treatment of large colorectal polyps, obviating the need for surgery in most instances.

192 able to conservative management, potentially obviating the need for surgery.

193 The percutaneous pseudocyst-cystostomy obviated the need for surgical revision of the exocrine

194 on (AR) in heart transplant recipients could obviate the need for surveillance endomyocardial biopsie

195 mat, termed the RNA invasive cleavage assay, obviates the need for target amplification or additional

196 ximize the sensitivity of the analyses while obviating the need for tedious sessions of microdissecti

197 tion of right to left bubble passage and may obviate the need for TEE in many patients after stroke.

198 inery is completely lacking in this species, obviating the need for TgPNP to metabolize MTI.

199 were absent from the locus in NOD Th0 cells, obviating the need for Th1 differentiation signals to es

200 inical, physiological, and radiological data obviate the need for the increased risk associated with

201 me imaging and no ionizing radiation and may obviate the need for the patient to schedule additional

202 Our approach obviated the need for the analysis of clones, PCR produc

203 This approach obviates the need for the classical N-protection/O-activ

204 The determination of the half-time obviates the need for the commonly used exercise test fo

205 This efficient inline injection system obviates the need for the excess sample that is required

206 vide a means for the delivery of leptin that obviates the need for the gene product to traverse the b

207 This process obviates the need for the harsh deprotection conditions

208 otein, not merely highly conserved ones, and obviates the need for the time consuming, expensive, and

209 ic stabilization from global delocalization, obviating the need for the concept of superaromaticity.

210 rred for dipyridamole-thallium testing, thus obviating the need for the more expensive testing.

211 ositol phosphate mass in cell extracts, thus obviating the need for the standard chromatography step.

212 bility can be incorporated into the analysis obviating the need for the ubiquitous assumption that th

213 Our approach obviates the need for transcript annotations and circumv

214 used to efficiently count transcripts while obviating the need for transcript-length normalization a

215 ugh adequate early excisional surgery should obviate the need for transplantation in these cases, wid

216 y for concentrating amino acids, which might obviate the need for transport induction by chlamydiae u

217 topic stimulation of this signalling cascade obviates the need for tuft cells in the epithelial cell

218 long-term central venous catheters may help obviate the need for tunneling of catheters.

219 ell is potentially more efficient because it obviates the need for two separate cell lines and purifi

220 ability of these simple complementary assays obviates the need for undesirable radiotracer-based assa

221 catalytically inactive ternary complexes and obviated the need for using 2',3'-dideoxy-terminated oli

222 finding is that the presence of acetonitrile obviates the need for using excess amounts of a more val

223 tical to parameters derived from blood, thus obviating the need for venous sampling in these patients

224 Positive serology obviates the need for vitreous biopsy and expedites the

225 ures all genes are derepressed at once, thus obviating the need for VP16 to initiate sequential derep

226 ined using nanomolar concentrations of BARAC obviated the need for washing steps.

227 ith targeted therapies or immune therapy may obviate the need for WBRT; prospective studies are requi

228 m of the simultaneously active conductances, obviating the need for weak coupling assumptions.

229 compared with conventional 2-tiered testing, obviating the need for Western blots.