ライフサイエンスコーパス: occludens

1 e postsynaptic density 95/discs large/zonula occludens 1 (PDZ) domain, involved in scaffolding and si

2 r the interaction of PSD-95/Discs Large/Zona Occludens 1 (PDZ) domain-containing proteins.

3 AT1 postsynaptic density 95/Discs large/zona occludens 1 (PDZ)-interacting domain.

4 integrated component of the occludin/zonula occludens 1 (ZO-1) adhesion complex at the BTB, structur

5 s express the tight junction proteins zonula occludens 1 (ZO-1) and occludin and form a barrier with

6 e tight junctional complex, including zonula occludens 1 (ZO-1) and occludin.

7 blood-brain barrier (BBB) occludin and zona occludens 1 (ZO-1) expression were significantly decreas

8 We previously found that depleting zonula occludens 1 (ZO-1) family proteins in MDCK cells induces

9 , claudin-23 (CLDN23), occludin, and Zonulae occludens 1 (ZO-1) in primary human keratinocytes.

10 to interact with a scaffold protein, zonula occludens 1 (ZO-1), demonstrating that one claudin affec

11 on of tight-junction-associated protein zona occludens 1 (ZO-1), translocation of ZO-1 to cell-cell b

12 nd the outer limiting membrane (OLM) (zonula occludens 1 and occludin).

13 ization of the tight junction protein zonula occludens 1 and of the junction-associated actin microfi

14 e cell elongation, and alter junctional zona occludens 1 and vascular endothelial-cadherin staining.

15 Reduced zonula occludens 1 expression was observed after HbG transfusio

16 localization of CD31, beta-catenin, and zona occludens 1 in junctions between sinus cells.

17 had a small decrease in expression of zonula occludens 1 in SB mucosa and significant decreases in ex

18 in-1 protein level, relocation of the zonula occludens 1 protein (ZO-1) to the TJ, and redistribution

19 n by the disengagement of the protein zonula occludens 1 protein from the tight junctional complex.

20 Zonula occludens 1 protein redistribution after bacteria coloni

21 In contrast, zonula occludens 1 was well preserved along intercellular borde

22 DZ (postsynaptic density 95/Discs large/zona occludens 1) ligand domains that can control their synap

23 DZ (postsynaptic density 95/Discs large/zona occludens 1) protein PICK1 (protein interacting with C k

24 DZ (postsynaptic density 95/Discs large/zona occludens 1) proteins that interact with glutamate recep

25 ing MUPP1 (multi-PDZ protein-1), ZO1 (zonula occludens 1), and Af6.

26 n), apoptosis (M30), tight junctions (zonula occludens 1), and neutrophil influx (myeloperoxidase) we

27 PDZ2 (postsynaptic density/Discs large/zona occludens 1), PDZ3, and PDZ4 of the PCP protein Scrb1 (S

28 DZ (postsynaptic density 95/Discs large/zona occludens 1)-domain interaction between GluR1 and SAP97,

29 f the tight junction scaffold protein zonula occludens 1, and disrupted junctional localization of th

30 Upon calcium repletion, occludin, zonula occludens 1, and E-cadherin failed to redistribute to th

31 in, plakoglobin, claudin-4, occludin, zonula occludens 1, and tricellulin were decreased at cell cont

32 , transient disruption of claudin-18, zonula occludens 1, and zonula occludens 2 localization to lung

33 ignificant decreases in expression of zonula occludens 1, claudin-1, and occludin in rectosigmoid muc

34 endothelial tight junction proteins (zonula occludens 1, claudin-5, and occludin), astrocyte activat

35 Ca2+ as revealed by the relocation of zonula occludens 1, the establishment of transepithelial electr

36 s evidenced by staining for F-actin and zona occludens 1.

37 ored the expression of E-cadherin and zonula occludens 1.

38 cts on the cytoplasmic plaque protein zonula occludens 1.

39 ROCK with the tight junction protein zonula occludens 1.

40 sion of the TJ molecules occludin and zonula occludens 1.

41 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1 (PDZ) binding domain, which is present on al

42 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1 (PDZ) binding motif, is localized to the pos

43 post-synaptic density-95/discs large/zonula occludens-1 (PDZ) domain of the human protein tyrosine p

44 the postsynaptic density-95/Discs large/zona occludens-1 (PDZ) domain protein interacting specificall

45 st synaptic density, discs large, and zonula occludens-1 (PDZ) domain protein SAP97 is a component of

46 g postsynaptic density-95/disks large/zonula occludens-1 (PDZ) domain-containing protein melanoma dif

47 protein of 95 kilodaltons, disc large, zona occludens-1 (PDZ) domain-containing proteins appear most

48 mediated signals and PSD-95-discs large-zona occludens-1 (PDZ) domain-dependent signals are required

49 Postsynaptic density 95/discs large/zonus occludens-1 (PDZ) domain-interacting motifs, in addition

50 post-synaptic density-95/discs large/zonula occludens-1 (PDZ) domain.

51 two postsynaptic density 95/disks large/zona occludens-1 (PDZ) domains and a tail ending in an ezrin-

52 ng postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domains have been shown to play critic

53 10 post-synaptic density-95/Discs Large/zona occludens-1 (PDZ) domains of PATJ could bind to the carb

54 two postsynaptic density-95/Discs large/zona occludens-1 (PDZ) domains of the scaffolding protein PSD

55 ng protein containing five PSD95/dlg/zonular occludens-1 (PDZ) domains that tether NORPA (phospholipa

56 postsynaptic density 95, discs large, zonula occludens-1 (PDZ) domains to engage the transport mechan

57 which is separate from the PSD95/dlg/zonular occludens-1 (PDZ) interacting domain.

58 ynaptic density-95 (PSD-95)/discs large/zona occludens-1 (PDZ) interaction to AMPA receptor (AMPAR)-b

59 ts carboxyl-terminal PSD-95/Discs Large/Zona Occludens-1 (PDZ) ligand and binding of the PDZ domain-c

60 s a postsynaptic density-95/Discs large/zona occludens-1 (PDZ) ligand, which is absent in EAAT2a.

61 a Postsynaptic density 95, Disk large, Zona occludens-1 (PDZ) motif.

62 in interactions with PSD-95/discs large/zona occludens-1 (PDZ) motifs.

63 ith postsynaptic density-95/discs large/zona occludens-1 (PDZ) proteins via a C-terminal PDZ binding

64 roteins that contain PSD-95-Discs Large-zona occludens-1 (PDZ), Src homology 3, and guanylate kinase

65 stsynaptic density (PSD)-95/discs large/zona occludens-1 (PDZ)-containing proteins that can assemble

66 ts postsynaptic density 95, disk large, zona occludens-1 (PDZ)-dependent binding (PDZ(-)) produced a

67 naptic density protein 95/disks large/zonula occludens-1 (PDZ)-domain proteins and A-kinase anchoring

68 and postsynaptic density-95/Discs large/zona occludens-1 (PDZ)] protein erbin and delta-catenin, a co

69 c density-95 (PSD-95)/discs large (Dlg)/zona occludens-1 (ZO-1) (PDZ) binding sites but lacks the cen

70 in ring (PAMR), and redistribution of zonula occludens-1 (ZO-1) and cadherins.

71 on, we investigated the expression of zonula occludens-1 (ZO-1) and E-cadherin, two molecules associa

72 roscopy using the tight junction marker zona occludens-1 (ZO-1) and end-binding protein-1 (EB-1), whi

73 rier using the tight junction markers zonula occludens-1 (ZO-1) and occludin.

74 ession of TJ transcripts, claudin-11, zonula-occludens-1 (ZO-1) and tricellulin in human SC endotheli

75 retention of Cx43 scaffolding protein Zonula Occludens-1 (ZO-1) at cell surfaces, suggesting that ZO-

76 e steady-state levels of occludin and zonula occludens-1 (ZO-1) at the BTB site via the p38 MAP kinas

77 e steady-state levels of occludin and zonula occludens-1 (ZO-1) at the BTB via the p38 mitogen activa

78 tion against IL-1beta-induced loss of zonula occludens-1 (ZO-1) at the tight junctions and alteration

79 Zonula occludens-1 (ZO-1) binds the carboxy terminus of Cx43, a

80 (TJ)-associated proteins occludin and zonula occludens-1 (ZO-1) following stimulation of brain microv

81 e and threonine residues, we screened zonula occludens-1 (ZO-1) immunoprecipitates for the existence

82 proteins) have been co-localized with zonula occludens-1 (ZO-1) in the tight junction of epithelial c

83 Src can disrupt the connexin43 (Cx43)-zonula occludens-1 (ZO-1) interaction, leading to down-regulati

84 ark of polarized epithelial cells and zonula occludens-1 (ZO-1) is a known key regulator of tight jun

85 Zonula occludens-1 (ZO-1) is a submembrane scaffolding protein

86 levels, the tight junctional protein Zonula Occludens-1 (ZO-1) is distributed intracellularly in gra

87 a marked decrease in beta-catenin and zonula occludens-1 (ZO-1) localization to the intercalated disc

88 binds to the Cx43 scaffolding protein zonula occludens-1 (ZO-1) with a higher affinity than does Cx43

89 The scaffold protein zonula-occludens-1 (ZO-1), a member of the MAGUK family of prot

90 ents yielded several proteins including zona occludens-1 (ZO-1), a structural protein previously iden

91 ression of TTF-1, aquaporin-5 (AQP5), zonula occludens-1 (ZO-1), and cytokeratins.

92 o assay for the presence of occludin, zonula occludens-1 (ZO-1), cadherin-5, and beta-catenin.

93 d known junctional proteins including zonula occludens-1 (ZO-1), occludin, and claudin-5.

94 l-cell contacts in close proximity to zonula occludens-1 (ZO-1), oxLDL treatment induced a disorganiz

95 ate tight-junction-associated protein Zonula Occludens-1 (ZO-1), which in turn plays a critical role

96 unction proteins such as occludin and zonula occludens-1 (ZO-1).

97 the tight junction-associated protein zonula occludens-1 (ZO-1).

98 tight junction proteins, occludin and zonula occludens-1 (ZO-1).

99 another element of the E-cad complex, zonula occludens-1 (ZO-1).

100 ction membrane proteins, occludin and zonula occludens-1 (ZO-1).

101 herin and tight junction (TJ) protein Zonula Occludens-1 (ZO-1).

102 c density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] binding domain and localizes to the

103 first two PDZ [PSD-95/Discs large (Dlg)/zona occludens-1 (ZO-1)] domains is necessary and sufficient

104 c density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] interactions with members of the PSD

105 c density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] proteins via its C-terminal PDZ-bind

106 s-1 mRNA are co-localized apically and zonal occludens-1 3' untranslated region-binding sites for CPE

107 The junctional proteins zonula occludens-1 and beta-catenin stained positively in both

108 amethasone-stimulated localization of zonula occludens-1 and beta-catenin to sites of cell-cell conta

109 zed mammary epithelial cells, in which zonal occludens-1 and claudin-3, apical tight-junction protein

110 n and the tight junction (TJ) proteins, zona occludens-1 and occludin, and the loss of the endothelia

111 nd tight-junction-associated proteins zonula occludens-1 and occludin.

112 s of tight junction proteins, such as zonula occludens-1 and Occludin.

113 hat postsynaptic density-95/discs large/zona occludens-1 and Src homology 3 domain-binding motifs loc

114 ng upregulation of dermal N-cadherin, Zonula Occludens-1 and the gap junction protein Connexin43 (Cx4

115 acellular flux, and redistribution of zonula occludens-1 and VE-cadherin but failed to induce apoptos

116 from mammary epithelial cells disrupts zonal occludens-1 apical localization and tight-junction distr

117 Connexin43 (Cx43) and zona occludens-1 are improperly localized in Akap9 mutant tes

118 RMP) homology, and PSD-95, Discs large, zona occludens-1 binding domains.

119 postsynaptic density-95, discs large, zonula occludens-1 binding motif in the C terminus of KV1.2alph

120 rge gap junction plaques, had reduced zonula occludens-1 binding, and displayed increased stability.

121 In addition, zonula occludens-1 co-localized with Muller cells within the co

122 esion via its effects on the occludin-zonula occludens-1 complex.

123 of epithelial markers E-cadherin and Zonula occludens-1 decreased while expression of mesenchymal ma

124 ion with both endogenous occludin and zonula occludens-1 demonstrating that exogenous occludin correc

125 minin, endothelial barrier antigen, and zona occludens-1 diminished in the ipsilateral cortex, sugges

126 synaptic density protein-95/discs large/zona occludens-1 domain (PDZ).

127 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1 domain of the distantly related membrane-ass

128 ERF1 postsynaptic density 95/disc-large/zona occludens-1 domain.

129 and postsynaptic density-95/Discs large/Zona Occludens-1 domains found in X11alpha and mLin-2/CASK bi

130 ing PostSynaptic Density-95/Discs large/Zona Occludens-1 domains, is an ortholog of the Drosophila tu

131 ytokine-induced hyperpermeability and zonula occludens-1 downregulation in NS-398-treated C2BBe1 cell

132 M-induced AR, with lower occludin and zonula occludens-1 expression.

133 suppressed epithelial E-cadherin and zonula occludens-1 expression.

134 permeability and reduced occludin and zonula occludens-1 expression.

135 ted with an increase in claudin-5 and zonula occludens-1 immunofluorescence at cell-cell contracts.

136 ng mammary ducts, depletion of CPEB or zonal occludens-1 impairs central cavity formation, indicating

137 ssociated with a potent protection of zonula occludens-1 linear border pattern in endothelial cells.

138 y, ectopic expression of CPEB enhances zonal occludens-1 localization.

139 Zonula occludens-1 molecules are also highly dynamic in this re

140 CPEB and zonal occludens-1 mRNA are co-localized apically and zonal occ

141 rescued when they are transduced with zonal occludens-1 mRNA containing, but not lacking, CPEB-bindi

142 ur data demonstrate that CPEB-mediated zonal occludens-1 mRNA localization is essential for tight-jun

143 a disc large tumor suppressor (Dlg1), zonula occludens-1 protein (zo-1) (PDZ) domain proteins.

144 orylation regulates the known role of zonula occludens-1 protein (ZO-1) in gap junction (GJ) function

145 ion, immunofluorescent assessments of zonula occludens-1 tight junction protein cellular distribution

146 d podocyte dysfunction, as evidenced by zona occludens-1 translocation to the membrane.

147 associated protein and MMP-9 substrate zonae occludens-1 was degraded after ischemia, but this was re

148 tsynaptic density-95)/Discs large/ZO-1 (zona occludens-1) (PDZ) domain-containing protein, erbin, in

149 Z (postsynaptic density 95, Disk large, Zona occludens-1) adaptor protein synectin was essential for

150 ction proteins (occludin, claudin-1 and zona occludens-1) are internalized through an NF-kappaB-depen

151 DZ (postsynaptic density-95/Discs large/zona occludens-1) binding domain interactions and triggers pr

152 DZ (postsynaptic density-95/Discs large/zona occludens-1) binding domain, which interacts with Tamali

153 The PDZ (PSD-95, discs large, zona occludens-1) binding motif at the distal end of the NR2

154 DZ (postsynaptic density-95/Discs large/zona occludens-1) domain independent and is regulated by alte

155 DZ (postsynaptic density-95/Discs large/zona occludens-1) domain proteins that target AMPA receptors

156 DZ (postsynaptic density-95/discs large/zona occludens-1) domain-based interactions play important ro

157 DZ (postsynaptic density-95/Discs large/zona occludens-1) domain-binding consensus at their C termini

158 hapsyn-110 is a PDZ (PSD-95/Discs large/zona occludens-1) domain-containing membrane-associated guany

159 DZ (postsynaptic density-95/Discs large/zona occludens-1) domain-containing protein interacting with

160 postsynaptic density 95, discs large, zonula occludens-1) domains and other regions.

161 (postsynaptic density 95/discs large/zonula occludens-1) domains are believed to provide relatively

162 (post-synaptic density-95/discs large/zonula occludens-1) domains are small, protein-protein binding

163 ough two of its PDZ (PSD-95/Discs large/zona occludens-1) domains as well as intact N-terminal and gu

164 ost-Synaptic Density-95, Discs Large, Zonula Occludens-1) domains followed by a short carboxyl-termin

165 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1) domains that bind the synaptic scaffolding

166 on and the first two PDZ (PSD-95, Dlg1, zona occludens-1) domains, the PDZ3 and guanylate kinase doma

167 tight junction protein (occludin and zonula occludens-1) expression.

168 by several PDZ (PSD-95, discs large, zonula occludens-1) proteins, which mediate protein-protein int

169 DZ (postsynaptic density-95/Discs Large/zona occludens-1) scaffold protein, INAD (inactivation no aft

170 in 43), Cx45 (connexin 45), and ZO-1 (zonula occludens-1) were identified as novel mRNA targets of FX

171 DZ (postsynaptic density 95/discs large/zona occludens-1), and Src homology 3 domains.

172 DZ (postsynaptic density-95/Discs large/zona occludens-1), Src homology 3, and guanylate kinase domai

173 DZ (postsynaptic density-95/Discs large/zona occludens-1)-binding kinase/T-LAK (lymphokine-activated

174 DZ (postsynaptic density-95/Discs large/zona occludens-1)-containing protein dX11/Mint/Lin-10, which

175 etase, expressed by Muller cells, and zonula occludens-1, a tight-junction protein.

176 kdown of Cx43 and N-cadherin, but not Zonula Occludens-1, accelerated cell migration in a scratch wou

177 d levels of alanine aminotransferase, zonula occludens-1, and interleukin-1beta compared with HS/CR a

178 phragm-associated protein P-cadherin, zonula occludens-1, and nephrin, a change consistent with loss

179 id (pyd), the Drosophila homologue of Zonula Occludens-1, are characterized by two phenotypes visible

180 duction of the tight-junction molecules zona occludens-1, claudin 3, and claudin 5 and other pathways

181 teins, including occludin, claudin-5, zonula occludens-1, junctional adhesion molecule-A, and endothe

182 bstrates of matrix metalloproteinase-9 (zona occludens-1, laminin), tissue inhibitor of matrix metall

183 o, in addition to loss of nephrin and zonula occludens-1, mesenchymal markers such as desmin, fibrobl

184 thelial cells such as cytokeratin 18, zonula occludens-1, mucins-1 and -2, antigen A33, and dipeptidy

185 ession of the tight junction proteins zonula occludens-1, occludin, and claudin-1 in the ileum follow

186 ssion of junctional proteins, such as zonula occludens-1, occludin, and claudin-4.

187 entative tight junction proteins (ie, zonula occludens-1, Occludin, Claudin-1) that critically regula

188 e expression of tight junction proteins zona occludens-1, occludin, claudin-1, and claudin-4, as well

189 acer permeability, junctional protein zonula occludens-1, occludin, claudins and E-cadherin expressio

190 ostsynaptic density (PSD)-95/Disc Large/Zona Occludens-1, Src homology 3, and guanylate kinase-like d

191 nd reduced expression of E-cadherin and zona occludens-1, whereas collagen-I and alpha-smooth muscle

192 er integrity and tight junction protein zona occludens-1, while the result for cells infected with th

193 the postsynaptic density-95/Discs large/zona occludens-1-binding domain of PTEN.

194 Cavity formation in zonal occludens-1-depleted cells is rescued when they are tran

195 post-synaptic density-95/discs large/zonula occludens-1-domain-containing (PDZ) proteins and serines

196 ning of the TJ molecules occludin and zonula occludens-1.

197 laminin, and the tight junction protein zona occludens-1.

198 , junctional adhesion molecule-A, and zonula occludens-1.

199 n kinase and increasing expression of zonula occludens-1.

200 ctor 3, Toll-interacting protein, and zonula occludens-1.

201 n kinase and increasing expression of zonula occludens-1.

202 Zonula occludens-1/NF-kappaB/CXCL8: a new regulatory axis for t

203 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1] domains of membrane-associated guanylate ki

204 rminus with the PDZ [PSD-95/Discs large/zona occludens-1] domains of PSD-95.

205 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1] domains of PSD-95/SAP90 (synapse-associated

206 DZ [postsynaptic density-95/Discs large/zona occludens-1]-domain containing protein, protein interact

207 of the blood-brain barrier (claudin 5a, zona occludens 1a and b).

208 silencing of the tight junction protein zona occludens 2 (ZO-2 KD) induces cell hypertrophy by two me

209 Zona occludens 2 (ZO-2) has a dual localization.

210 f claudin-18, zonula occludens 1, and zonula occludens 2 localization to lung tight junctions in situ

211 nd protein for claudin-5, occludin, and zona occludens 2 were also reduced in infected cells.

212 nction proteins (claudin 1, 14, 16, and zona occludens 2), nine gap junction proteins (connexin 26, 3

213 its PDZ-binding motif to interact with zona occludens-2 (ZO-2) protein, which promotes YAP's translo

214 cally interact with the protein ZO-2 (zonula occludens-2).

215 of inositol pentakisphosphate 2-kinase, zona occludens 3, and FAT tumor suppressor 2).

216 ranule-like cytoplasmic structures, and zona occludens 3.

217 n interact with the carboxyl termini of zona occludens-3 (ZO-3) and claudin 1, respectively.

218 dissolution of some tight junctions (zonula occludens) and zonula adherens without loss of desmosome

219 ochemistry showed that E-cadherin and Zonula occludens are down-regulated in MCF-7/CXCR4-DeltaCTD cel

220 Staining for the zonula occludens complex (ZO-1) and adherens complex (alpha, be

221 in, Crumbs, and two PSD95/discs large/zonula occludens domain proteins, protein associated with Lin s

222 DZ (postsynaptic density 95/discs large/zona occludens) domain AMPAR-binding protein, is bidirectiona

223 he His-ZO-1-PDZ1 (first PDZ domain of zonula occludens) domain that binds Neph1-CD was also analyzed

224 0, a postsynaptic density 95/disc-large/zona occludens-domain containing protein: GLR-1 accumulates i

225 postsynaptic density-95, discs large, zonula occludens) domains play a general role in recruiting rec

226 The scaffold proteins of the zonula occludens family are required for the correct localizati

227 subapical region overlapping with ZO-1 (zona occludens-I), a key component of the TJ.

228 The tight junction, or zonula occludens, is a specialized cell-cell junction that regu

229 is accomplished in vertebrates by the zonula occludens, or tight junction.

230 inal postsynaptic density 95/disc-large/zona occludens (PDZ) binding domain increased its range by ap

231 inal postsynaptic density 95/disc-large/zona occludens (PDZ) binding motif.

232 the postsynaptic density-25/Discs large/zona occludens (PDZ) domain of RIM.

233 tes interactions with PSD-95/disc large/zona occludens (PDZ) domain-containing proteins.

234 lti-postsynaptic density-95/discs large/zona occludens (PDZ) protein that binds to the glutamate rece

235 are postsynaptic density 95/disc-large/zona occludens (PDZ)-domain-containing scaffolding proteins f

236 ls, because the presence of an intact zonula occludens prevented passage.

237 tigen 2), blood-retinal barrier [anti-zonula occludens protein 1 (ZO-1) and anti-occludin], and hypox

238 IV, laminin, claudin-5, occludin, and zonula occludens protein 1 was also better preserved in neonata

239 Drosophila discs large protein, and the zona occludens protein 1).

240 vious change of claudin-1, claudin-4, zonula occludens protein 1, and zonula occludens protein 2 expr

241 in-4, zonula occludens protein 1, and zonula occludens protein 2 expressions was observed.

242 PDZ (postsynaptic density/disc large/zonula occludens) protein binding assays, that these soluble pr

243 PDZ (postsynaptic density 95/disc large/zona occludens) protein that assembles macromolecular complex

244 binds to the N-terminal PDZ domain of zonula occludens proteins (PDZ1).

245 Zonula occludens proteins are multidomain proteins usually loca

246 cludin but no change in expression of zonula occludens proteins ZO-1 and -2.

247 cells, this complex localizes to the zonula occludens (tight junctions) and appears to regulate epit

248 Zonula occludens toxin (Zot) is an enterotoxin elaborated by Vi

249 these structures can be modulated by Zonula occludens toxin (Zot).

250 The intestinal secretion induced by zonula occludens toxin follows the opening of tight junctions c

251 Zonula occludens toxin induced a time- and dose-dependent decre

252 Zonula occludens toxin is a novel toxin elaborated by Vibrio ch

253 e tissues were also fixed, exposed to zonula occludens toxin, and processed for fluorescence microsco

254 ells is regulated by tight junctions (zonula occludens), we wished to determine whether they also reg

255 tural and functional integrity of the zonula occludens (ZA) induced by ATP depletion of renal tubular

256 We have determined that the zonula occludens (ZO) family of TJ plaque proteins sequesters c

257 of this barrier are dependent on the zonula occludens (ZO) membrane-associated guanylate kinase (MAG

258 The zonula occludens (ZO) protein-1 is a membrane-associated compon

259 Zona occludens (ZO) proteins are molecular scaffolds localize

260 Thus the manner in which the zonula occludens (ZO) proteins multimerize has implications for

261 Specific TJ proteins, such as zonula occludens (ZO) proteins, localize not only at the cell-c

262 f these junctions is dependent on the zonula occludens (ZO) proteins, members of the membrane-associa

263 The zonula occludens (ZO) subfamily of membrane-associated guanylat

264 The zonula occludens (ZO)-1 and -2 proteins have context-dependent

265 Zonula occludens (ZO)-1 is a member of the MAGUK (membrane-asso

266 The tight junction (TJ) protein zonula occludens (ZO)-1 links the intracellular domain of TJ-tr

267 Here, we show that zonula occludens (ZO)-1 localizes preferentially to the periphe

268 junction proteins, namely, occludin, zonula occludens (ZO)-1, and ZO-2 in the caveolar fraction of H

269 on of occludin, claudin-1, claudin-5, zonula occludens (ZO)-1, and ZO-2, and a TJ accessory protein a

270 tide exchange factor (GEF) 2, but not zonula occludens (ZO)-1, in epithelial cells, and these interac

271 the distribution of the TJ proteins, zonula occludens (ZO)-1, ZO-2, and cingulin, examination of the

272 ion molecule-A (JAM)-A, occludin, and zonula occludens (ZO)-1.

273 ite of arachidonic acid, by stimulating zona occludens (ZO)-2 tyrosine phosphorylation and its dissoc

274 In cell culture zonula occludens (ZO)-family proteins are important for assembl

275 ant disruption of actin filaments and zonula occludens (ZO-1), and a decrease in transepithelial resi

276 on components [Occludin, Claudin-1, -2, Zona occludens (ZO-1, -2)].