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1 iency using both mRNA abundance and ribosome occupancy.
2 e2 and by reduction in RNA polymerase Pol II occupancy.
3 y filter, which leads to a change in the ion occupancy.
4 ers with conserved or diverged combinatorial occupancy.
5 d sites whereas BRD2 is dispensable for CTCF occupancy.
6 sequestered up to 15% of the total ribosome occupancy.
7 of gut colonization determines colonic crypt occupancy.
8 conserved activity despite divergence in TF occupancy.
9 slow decrease, in Rpd3L histone deacetylase occupancy.
10 gene expression and increases paused pol II occupancy.
11 stant infusion to measure changes in 5-HT1BR occupancy.
12 differentially regulate BRWD2/PHIP chromatin occupancy.
13 portunistic response to diminishing ecospace occupancy.
14 perature to a fraction of its thermal phonon occupancy.
15 used to determine the glycosites and glycan occupancy.
16 ation of ribosomes and tRNAs as well as tRNA occupancy.
17 rules that govern transcription factor (TF) occupancy.
18 o cross-linking to RNA and reduced chromatin occupancy.
19 proximity was restored without mediator core occupancy.
20 particularly following a year with high ICU occupancy.
21 yeast, promoters encode for high nucleosome occupancy.
22 at CysE should outcompete the toxin for CysK occupancy.
23 ic regions with regeneration-responsive H3.3 occupancy.
24 and histone H3 and their IL-8/CXCL8 promoter occupancy.
25 s of co-associations and co-divergence in TF occupancy.
26 mic response that was related to the 5-HT1BR occupancy.
27 h drug concentrations ensured prolonged CCR2 occupancy.
28 tic genome-wide reduction of HNF4A and HNF4G occupancy.
29 ainly as a function of air exchange rate and occupancy.
30 re associated with shifts to colder climatic occupancy.
31 e proteomics to determine S-nitrosation site occupancy.
32 ng, APC vessel niche affinity and APC vessel occupancy.
33 in interactions sustain conserved collective occupancy.
34 mation in the absence of mediator or cohesin occupancy.
35 tally determined atomic sites and fractional occupancies.
36 severs actin weakly across a broad range of occupancies.
37 s along coding sequences, and ribosome codon occupancies.
38 mmunity to elk (Cervus elaphus) winter range occupancy across a long-term foraging exclusion experime
39 cription factor the unique ability to extend occupancy across DNA regions far from specific binding s
41 500 or more beds in the highest quartile of occupancy (adjusted odds ratio, 18.9; 95% CI, 14.0-25.5;
42 eaching hospitals in the highest quartile of occupancy (adjusted odds ratio, 7.3; 95% CI, 5.3-9.9; p
44 oups and individual OTUs exhibiting distinct occupancy and abundance distributions aligned with envir
46 c communication linking cryptic binding site occupancy and allosteric inactivation of KHSV Pr that ca
47 ther fast or slow, leads to decreased Pol II occupancy and apparent reduction in elongation rate in v
48 rthermore, CHD9 and BRM were required for GR occupancy and chromatin remodeling at GR-binding regions
49 CU costs at the patient level are day 1 room occupancy and day 1 mechanical ventilation, mortality be
50 few sampling visits were needed to estimate occupancy and detectability with good precision, and to
52 nctional impact on transcription factor (TF) occupancy and enhancer activity remains poorly understoo
53 leads to strong depletion of enhancer Pol II occupancy and eRNA synthesis, concomitant with downregul
54 riptional regulator influences its chromatin occupancy and function, we leveraged the extensive bioch
55 for high-resolution measurements of both DNA occupancy and gene expression on large-scale libraries o
57 odeling enzymes to selectively influence DNA occupancy and gene regulation by a transcription factor.
58 e fusion proteins do not incorporate to full occupancy and have modest effects on virus replication a
61 rom those that identify transcription factor occupancy and initiation of transcription to long-lastin
63 f the genome with relatively high nucleosome occupancy and low co-occupancy by other transcription fa
64 1 (SIRT1) correlated with lower acetylation occupancy and lower levels of ribosomal proteins, includ
66 Genome Sequencing (MAPit-BGS) and nucleosome occupancy and methylome sequencing (NOMe-seq) have been
67 bly, affected introns are enriched for H2A.Z occupancy and more likely to contain nonconsensus splice
68 enhancers with diverged motifs yet conserved occupancy and others with diverged occupancy yet conserv
70 A1 site eliminated LDB1 complex and mediator occupancy and resulted in loss of LCR/beta-globin proxim
72 ism spectroscopies reveal that both the site occupancy and the identity of the cation perturb the ele
73 eptor beta (ERbeta), which reduces chromatin occupancy and transcriptional activity of double homeobo
75 G methylation of RE1 sequences, reduced REST occupancy, and consequently release of the transcription
76 on of KDM5B leads to altered RNAPII promoter occupancy, and decreased RNAPII initiation and elongatio
78 AC silencing, real-time attachment geometry, occupancy, and tension at individual mammalian kinetocho
79 , teaching status, ownership, intensive care occupancy, and urbanicity for each hospital in each year
82 diminished cell-cycle changes in nucleosome occupancy around origins in the orc1-161 mutant are asso
83 ting that proper establishment of nucleosome occupancy around origins is a critical step for regulati
84 oss the S. cerevisiae genome, and nucleosome occupancy around origins significantly correlates with t
86 drug development and confirms high receptor occupancy as a key parameter when targeting chemokine re
88 e conclude that encoding for high nucleosome occupancy, as in the human genome, is in fact a universa
90 ted increased promoter and gene body H3K4me3 occupancy at DAC-responsive genes compared with DAC alon
93 35), were found to have robust P2X7 receptor occupancy at low doses in rat with ED50 values of 0.06 a
96 analysis revealed increased genome-wide BRD4 occupancy at promoter and enhancer regions in CD4(+) T c
97 link between cognitive enhancement and MEF2C occupancy at promoters harboring canonical and variant M
100 cture, protein-RNA interactions and ribosome occupancy at the genome level, a renewed enthusiasm towa
101 t Kapalpha facilitates Kapbeta1 turnover and occupancy at the NPC in a RanGTP-dependent manner that i
102 dynamics (MD) simulations, we probe the ion occupancy at the S1 binding site in the constricted stat
104 tegies including avoidance of desflurane and occupancy-based ventilation have the potential to lessen
105 ent response to feeding, the rise of Pol III occupancy before the onset of the night reflects a circa
106 ondition, (2) detection of differential site occupancy between conditions, and (3) estimation of comb
107 sine residues mainly exhibit low acetylation occupancy, but challenges in sample preparation and anal
108 ch a response did not entail changes in Abf1 occupancy, but it was paralleled by a quick increase, fo
111 tagonist GR127935, consistent with low basal occupancy by endogenous serotonin.SIGNIFICANCE STATEMENT
112 tistical dispersion of the nanodot molecular occupancy by Fc-PEG chains can be reliably quantified, e
113 chromatin marks, DNase hypersensitivity, and occupancy by multiple transcription factors, which confi
114 ycan patterns, glycosylation site, and their occupancy by N-glycans are all detected and identified i
117 the TH2 subset of helper T cells to enhancer occupancy by the BATF-IRF4 transcription factor complex
118 that interplay to drive transcription factor occupancy, chromatin state, and gene expression in compl
119 e extent to which shifts in genome-wide CTCF occupancy contribute to the 3D reconfiguration of fine-s
120 Unexpectedly, while promoter-proximal BRD4 occupancy correlated with gene expression, genes which d
122 s near lung cancer-associated genes, and its occupancy correlates with increased genome accessibility
124 In the absence of dopamine D2/3 receptor occupancy data to inform antipsychotic prescribing for p
129 romatin accessibility, and RNA polymerase II occupancy demonstrate that BTBD18 facilitates expression
132 -occupied elements are common in the genome, occupancy does not predict function, and GATA-2-dependen
133 ility predominate over changes in nucleosome occupancy during rapid transcriptional induction during
134 ogram of putative enhancers that revise H3.3 occupancy during regeneration, overlaid upon a genome-wi
136 ectedly, we observe a sharp decrease in CTCF occupancy during the transition from naive/primed plurip
141 ere is a therapeutic window of D2/3 receptor occupancy for optimal treatment of psychosis in Alzheime
142 pressure to 10(-6) Torr enriched the Al site occupancy fraction at the outermost surface from 0.245(1
145 However, human nucleosomes have higher DNA occupancy, globally reduce RNA content, and slow adaptat
146 heoretically, on the interplay between space occupancy, guest conformation, and chiral recognition ba
147 educed levels of nuclear HIF1alpha, promoter occupancy, HIF-dependent gene expression and cell viabil
148 g allele-specific methylation and nucleosome occupancy in cell lines, and colon and tumor samples, an
149 datasets detected increases in polymerase II occupancy in DoG regions after heat shock, supporting ou
152 ulpride blood concentration and central D2/3 occupancy in older people with Alzheimer's disease by co
153 aily dose of 420 mg achieved BTK active-site occupancy in patients with chronic lymphocytic leukemia
154 simulation, evaluation of differential site occupancy in positive and negative controls, and compari
155 prove reading frame and shed light on A-site occupancy in ribosome profiling experiments more broadly
156 ally at genes characterized by elevated H3.3 occupancy, including the 45S ribosomal DNA (45S rDNA) lo
157 resumed that subsequent reduction in cofilin occupancy inhibits filament severing, but this hypothesi
159 e conventional representation of the orbital occupancies is incorrect in that the states have more un
160 ch intermediate around the cycle and how the occupancy is altered by changes in actin concentration f
161 ural modification with changes in trap state occupancy is likely a general feature of reduced TiO2 sy
162 r interactions are anchored by CTCF, and its occupancy is lost in parallel with loop decommissioning
163 nized more sites and those with broader site occupancy, larger seed mass, and higher habitat fidelity
169 ce in sound levels regardless of single room occupancy, mechanical ventilation status, or illness sev
170 fit, provided little extra information over occupancy models and were at greater risk of closure vio
173 e from oligonucleotide design and nucleosome occupancy models, we systematically evaluated candidate
175 a3), we interrogate their chromosomal target occupancies, modulation of global transcription and chro
176 h), and hospitals in the highest quartile of occupancy (net, +10,157 beds; 54.0% of total growth).
177 This contrasts with the VDR and PPARgamma co-occupancy observed on PGC1beta and LPL gene regulatory r
178 diagnosis, mortality in the unit, daily unit occupancy (occupying a bed at midnight), and length of m
179 We tested whether changes in nucleosome occupancy occurred on the set of genes that is activated
180 f 10(-10) Torr, but rather an increased Al-O occupancy occurred, which was accompanied by a larger ou
183 threshold concentration of 20 ng/ml and D2/3 occupancies of 43% (caudate), 25% (putamen), 43% (thalam
184 hreshold concentration of 60 ng/ml, and D2/3 occupancies of 61% (caudate), 49% (putamen) and 69% (tha
188 Hence, we show that the structures and atom occupancies of the jets stem from the quantum fluctuatio
192 rther, a quantitative description of the DNA occupancy of a polymerizing transcription factor is lack
193 , in HBV replicating cells RNA polymerase II occupancy of all SALL4 exons increased, suggesting CpG d
201 wide target mapping unveils the preferential occupancy of Fbxl19 on CpG island-containing promoters,
202 ChIP experiments demonstrate that in vivo occupancy of Fur correlates with derepression of each op
203 In contrast, memantine binding increases occupancy of GluN1/2A and native NMDAR desensitized stat
208 reflects the binding specificity and genome occupancy of methylcytosine binding protein 2 (MeCP2).
209 ein characterization: (1) estimation of site occupancy of modifications in one condition, (2) detecti
211 mapping reveals that there is significant co-occupancy of Nanog (Nanog homeobox) and Hoxa1 on many co
213 otif at the hTERT promoter was essential for occupancy of NME2 and the REST repressor complex on the
219 ntal genes in fly embryos, with analogous co-occupancy of PRC1 and a Br140 ortholog, BRD1, at bivalen
220 infection, there was a significantly reduced occupancy of RNA polymerase II and the essential mitotic
221 recipitation (ChIP) assays RNA polymerase II occupancy of SALL4 gene, as a function of HBV replicatio
225 cription factors depend on each other for co-occupancy of target enhancers associated with key differ
226 accessibility by ATAC-seq, we found that the occupancy of target sequences by Bcd is not primarily de
227 A general principle is concluded that the eg occupancy of the active cation in the octahedral site is
229 Mad2 binding to this Cdc20 molecule; and (3) occupancy of the APC/C with full MCC, where Mad3 and Apc
231 s and ATX revealed a novel binding mode with occupancy of the hydrophobic pocket and channel of ATX b
232 entation has almost no influence on the site occupancy of the intermediate consumer in the tri-trophi
236 ite) and mechanism (competition with UTP for occupancy of the NTP addition site) that differ from tho
237 lar region and the two termini competing for occupancy of the other pole), or a reverse J-shaped moti
240 asic dose-response curves indicated that the occupancy of the protomers in the Env trimer governs vir
241 ric mechanism in which information regarding occupancy of the RAG-2 PHD is transmitted to RAG-1.
242 A mechanism based on axonal sprouting and occupancy of the vacant synaptic space due to deafferent
243 xplicitly calculate the probabilities of the occupancy of these states and show their dependence on t
244 Rgamma regulatory region precludes PPARgamma occupancy of this site, based on the observation that PP
245 allele-specific transcription factor binding occupancy of three liver-specific transcription factors
246 t of OL maturation genes and reduces the DNA occupancy of YY1, a transcription factor required for OL
248 unoprecipitation in order to reveal Mediator occupancy on DNA genome-wide, and to identify proteins i
249 that, under SAM-limiting conditions, METTL16 occupancy on hp1 increases due to inefficient enzymatic
256 enetic variations, transcription factor (TF) occupancy, or histone modification through next generati
260 aceable distribution volume (VND) via Lassen occupancy plotting and thereby estimate BPND in brain.
262 ells and on meta analysis of their chromatin occupancy profiles, we speculate that Cg limits Eya-So a
265 reshold steady state blood concentration and occupancy required to elicit a clinically relevant respo
266 d state, because a CaCC with a single Ca(2+) occupancy requires membrane depolarization in order to o
267 in the genome that redistribute CTCF/cohesin occupancy rewire DNA cleavage sites to novel loop anchor
268 on of processes such as transcription factor occupancy, RNA polymerase II recruitment and initiation,
269 e in each cell cycle phase, while nucleosome occupancy showed notable phase dependent fluctuation.
271 ynamic responses, even at a 5-HT1BR cerebral occupancy similar to the one obtained with a high dose o
274 nlike other techniques that measure receptor occupancy, such as flow cytometry, this technique does n
275 rate global effects of HuR knockdown on Ago2 occupancy, suggesting a co-regulatory relationship.
276 ermore, we report an enrichment of HOT (high-occupancy target) regions near TAD boundaries and invest
277 eins and observed an enhancement in N-glycan occupancy that was further supported by modeling the hig
278 evere disorder, large thermal motion and low occupancies, the reliable crystallographic determination
280 al size and teaching status were modified by occupancy: the greatest odds of increasing ICU beds were
281 ns throughout the sequence to report on hole occupancy, thereby enabling detailed monitoring of the h
282 victs Polycomb factors within minutes of its occupancy, thereby establishing a new mechanism for the
283 erg3 mutant, the SAGA complex increases its occupancy time on many of the induced ergosterol and ana
284 This core program is associated with high-occupancy TP53 enhancers, high levels of paused RNA poly
286 plays an integral role in regulating RNAPII occupancy, transcriptional initiation and elongation, an
287 enhancer landscape and transcription factor occupancy (using ChIP-seq), we show that synergistic gen
288 gh Google Maps, we investigated whether high-occupancy vehicle (HOV) policies can combat congestion.
290 derate expression and promoter-proximal BRD4 occupancy were most highly regulated and sensitive to BR
291 ent severing with minimal effects on cofilin occupancy, whereas filament twisting enhances cofilin di
293 cell loading our device has an 80% microwell occupancy with 1-4 cells, of which 36% of wells containe
296 controls, and comparisons of estimated site occupancy with orthogonal experimental measurements of N
297 tion factor REST binds to xCT promoter in co-occupancy with the epigenetic marker H3K27ac to regulate
299 esting that the unique architectural protein occupancy within enhancers is one contributor to enhance
300 conserved occupancy and others with diverged occupancy yet conserved activity, emphasising the need t
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