ライフサイエンスコーパス: octadecadienoic acid

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1 nstable allene oxide, 9(R),10-epoxy-10,12(Z)-octadecadienoic acid.

2 ts from the lipid hydroperoxide, hydroperoxy octadecadienoic acid.

3 noic acid and 13-hydroperoxy-cis-9, trans-11-octadecadienoic acid.

4 ng the reaction with 13S-hydroperoxy-9Z, 11E-octadecadienoic acid.

5 6-dihydroxy-9,12-, and 9, 10-dihydroxy-12,15-octadecadienoic acids.

6 oxygenase-1 is 13(S)-hydroxy-cis-9, trans-11-octadecadienoic acid (13(S)-HODE).

7 tadecadienoic acid (9-HODE), 13-hydroxy-9,11-octadecadienoic acid (13-HODE), and thiobarbituric acid

8 ctivation requires 13-hydroperoxy-9(Z),11(E)-octadecadienoic acid (13-HPOD), which suggests that it i

9 roxides revealed that 13S-hydroperoxy-9Z,11E-octadecadienoic acid (13-HpODE) was the most potent oxid

10 at 4-HPNE formed from 13S-hydroperoxy-9Z,11E-octadecadienoic acid (13S-HPODE) retains >90% S configur

11 prostanes (isoprostane), 9-hydroperoxy-10,12-octadecadienoic acid (9-HODE), 13-hydroxy-9,11-octadecad

12 idized 18:2n-6 to 9R-hydroperoxy-10(E),12(Z)-octadecadienoic acid (9R-HPODE).

13 s nearly racemic from 9S-hydroperoxy-10E,12Z-octadecadienoic acid (9S-HPODE).

14 e (*NO) by nitrolinoleic acid (10-nitro-9,12-octadecadienoic acid and 12-nitro-9,12-octadecadienoic a

15 The LNO(2) isomers 10-nitro-9-cis, 12-cis-octadecadienoic acid and 12-nitro-9-cis, 12-cis-octadeca

16 ydroperoxide, 9-hydroperoxy-trans-10, cis-12-octadecadienoic acid and 13-hydroperoxy-cis-9, trans-11-

17 octadecenoic acid (12-IODE) to produce 9, 11-octadecadienoic acid and iodide ion.

18 adecadienoic acid and 5S,8R-dihydroxy-9Z,12Z-octadecadienoic acid and that PpoC is responsible for 10

19 ure of 30% 9S-HPODE (9S-hydroperoxy-10E, 12Z-octadecadienoic acid) and 70% 13S-HPODE (13S-hydroperoxy

20 ) and 70% 13S-HPODE (13S-hydroperoxy-9Z, 11E-octadecadienoic acid) at pH 7.

21 9- cis,11- trans-Octadecadienoic acid (conjugated linoleic acid), a poten

22 trate dihydro analog cis-12,13S-epoxy-9Z,15Z-octadecadienoic acid did not cyclize in the presence of

23 F(2)-isoprostanes, hydroxy- and hydroperoxy-octadecadienoic acids (H(P)ODEs), and their precursors,

24 cific oxidized fatty acids including hydroxy-octadecadienoic acids (HODEs), oxo-octadecadienoic acids

25 ent of either LDL or LDL(-) releases hydroxy-octadecadienoic acids (HODEs), potent PPAR alpha activat

26 the products (13-(S)-hydroperoxy-9,11-(Z,E)-octadecadienoic acid (HPOD) and 15-(S)-hydroperoxyeicosa

27 lipid hydroperoxide 13(S)-hydroperoxy-9Z,11E-octadecadienoic acid (HpODE) is found in submacular Bruc

28 nteraction of ascorbic acid with hydroperoxy octadecadienoic acid in vitro, were identified by tandem

29 -9,12-octadecadienoic acid and 12-nitro-9,12-octadecadienoic acid; LNO2) are reported.

30 noleic acid (9-, 10-, 12-, and 13-nitro-9,12-octadecadienoic acids) (m/z 324.2) and nitro-oleic acid

31 ed fatty acids such as 10- and 12-nitro-9,12-octadecadienoic acid (nitrolinoleic acid, LNO(2)) exhibi

32 g hydroxy-octadecadienoic acids (HODEs), oxo-octadecadienoic acids (oxoODEs), and hydroxy-eicosatetra

33 ver, the demonstration that these isomers of octadecadienoic acid protect against cancers in rodents

34 the sn-2 acyl chain is derived from cis, cis-octadecadienoic acid, the Tm-lowering effect has the fol

35 nificantly higher cord blood vein wall trans octadecadienoic acid values than did neurologically norm

36 odd-numbered positions, e.g. 9-cis, 11-trans-octadecadienoic acid, was investigated.

37 adecadienoic acid and 12-nitro-9-cis, 12-cis-octadecadienoic acid were synthesized and compared with

38 cid (13-HPOT) and 13S-hydroperoxy-9(Z),11(E)-octadecadienoic acid, whereas LeHPL showed a strong pref

39 ersus the product, 13-hydroperoxy-9,11-(Z,E)-octadecadienoic acid, with a K(i) of 17.5 +/- 3.8 microM

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