ライフサイエンスコーパス: octane

1 icarboxylate; dabco = 1,4-diazabicyclo[2.2.2]octane).

2 histidine, Tris, and 1,4-diazabicyclo[2.2.2]octane).

3 loride) cross-linked with diazabicyclo[2.2.2]octane.

4 leading to formation of a 6-azabicyclo[3.2.1]octane.

5 duct, or to an exocyclic vinyl bicyclo[3.3.0]octane.

6 nti-fluoro-8-anti-hydroxy-6-azabicyclo[3.2.1]octane.

7 ension, including alkanes such as decane and octane.

8 N, of 5700 (k' = 0.21) for the same analyte, octane.

9 ngement products were observed for spiro[2.5]octane.

10 he bicyclopentane ring than in bicyclo[2.2.2]octane.

11 The solutes considered range from methane to octane.

12 of reverse micelles of Aerosol OT (AOT) in n-octane.

13 catalyzes the hydrogenation of 1-octene to n-octane.

14 rted into polysubstituted 2-oxabicyclo[3.3.0]octanes.

15 nes and 4-anti-Y-8-anti-X-6-azabicyclo[3.2.1]octanes.

16 tion for the synthesis of 6-azabicyclo[3.2.1]octanes.

17 and all three benzo-annulated bicyclo[2.2.2]octanes.

18 (I) iodide to afford azapalladabicyclo[3.2.1]octanes.

19 sopropyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane 1-oxide (Isopropyl Bicyclophosphate or IPBCP) wer

20 The suitability of 1-borabicyclo[2.2.2]octane (1) as a structural element for liquid crystals w

21 -amino}-acetylamino-3,6-dioxa-8-pteroylamino-octane (1), was employed for synthesis of the correspond

22 nce in acidity between 4-chlorobicyclo[2.2.2]octane-1-carboxylic acid and the parent acid (6.2 kcal/m

23 )phenyl]-2 beta-propanoyl-8-azabicyclo[3.2.1]octane (13b) which had a Ki of 0.1 nM at 5-HT transporte

24 Stereoisomeric 2,5-diazabicyclo[2.2.2]octanes 14 and 15 were prepared in a chiral-pool synthes

25 ,exo-2,6-cis-diphenethyl-1-azabicyclo-[2.2.2]octane (2 and 3), has been developed.

26 Norcarane (1) and spiro[2.5]octane (2) yield different product distributions dependi

27 2-(Pyridin-3-yl)-1-azabicyclo[2.2.2]octane, 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, and

28 oquinolin-3-yl)-4'H-4-azaspiro[bicyclo[2.2.2]octane-2,5'oxazol]-2' -amine (BMS-902483), a potent alph

29 for the preparation of chiral bicyclo[2.2.2]octane-2,5-dione, the precursor of useful chiral diene l

30 alyzes the desymmetrization of bicyclo[2.2.2]octane-2,6-dione to yield [(S)-3-oxocyclohexyl]acetic ac

31 he bicyclic diketone substrate bicyclo[2.2.2]octane-2,6-dione was found the product of the asymmetric

32 -biphenyl-4-yl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-c arboxylic acid methyl ester (11; K(i) = 15.1

33 3-(benzoyloxy)-8-methyl-8-azabicyclo [3.2.1] octane-2-carboxamido-hexanoic acid).

34 25)I]iodobenzene)-1-ethyl-8-azabicyclo[3.2.1]octane-2-carboxylate ([ (125)I]-N-IACoc) and N-propyl- N

35 methyl-3-(beta-styrenyl)-8-azabicyclo[3.2.1] octane-2-carboxylate.

36 onyl)methyl]-6-acetamido-6-azabicyclo [3.2.1]octane (28), 1-(1,3-dithian-2-yl)-5-[(ethoxycarbonyl)met

37 carbonyl)methyl]-6-acetyl-6-azabicyclo[3.2.1]octane (29), respectively, are reported, as well as for

38 ] to form 7,7,8,8-tetrachlorodispiro[2.0.2.2]octane (3)

39 thyl N-ethyl (hydroxymethyl)azabicyclo[3.2.1]octane (3) are also described.

40 phenyl)-4-n-propyl-2,6,7-trioxabicyclo[2.2.2]octane ([(3)H]EBOB) and [(3)H]3,3-bis-trifluoromethylbic

41 yl-N-(phenylmethyl)-spiro[1-azabicyclo[2.2.2]octane-3,2' (3'H)-furo[2,3-b]pyridin]-5'-amine 1 was syn

42 e of AR-R17779, (-)-spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin-2'-one] (4a), a potent full agoni

43 eceptor agonist (-)-spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin-2'-one] (AR-R17779) is presented.

44 25)I-iodo-3-furanyl)spiro[1-azabicyclo[2.2.2]octane]-3,2'(3' H)-furo[2,3-b]pyridine 4 was synthesized

45 edure, the functionalized 8-azabicyclo[3.2.1]octane 32, which is a potential intermediate for the syn

46 2,5-thiadiazol+ ++-3-yl] -1-azabicyclo[3.2.1]octane (35, LY316108/NNC11-2192) was found to offer an e

47 hydroxymethyl-substituted azabicyclo[3.2.1.]octane (40) and then selective protection to form a prot

48 3-(5-chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (56, TC-6683, AZD1446) with favorable pharmaceuti

49 e (4S), 8-carbena-endo-tricyclo[3.2.1.0(2,4)]octane (5S), 3-carbenabicyclo[3.1.0]hexane (3S), 2-carbe

50 rbonylamino)-4-iodo-7-oxo-6-azabicyclo[3.2.1]octane-6-carboxylate 11.

51 S,7S)-N-hydroxy-6-carboxamide-5-azaspiro[2.5]octane-7-carboxamides as the first potent and selective

52 oxy]ethylidene]-8-methyl-8-azabicyclo[3.2.1] octane (8) was found to have the highest affinity and se

53 to afford 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane-8-ones (18, 26, and 36a/b) with endo,exo stereoch

54 2-ene (8), and tetracyclo[3.3.0.0(2,8)0(4,6)]octane (9).

55 tain higher fuel economy by utilizing higher octane (98 RON) gasoline.

56 ate model, molecular dynamics simulations in octane, a lipid bilayer mimetic, were carried out.

57 In the OCTANE/A5208 study of initial antiretroviral therapy (AR

58 shed results from women participating in the OCTANE/A5208 trial 1 who had taken sdNVP and initiated N

59 re starting first-line NVP-based cART in the OCTANE/A5208 trial 2.

60 use of a lithiated asymmetric bicyclo[3.2.1]octane (ABO) ortho ester.

61 led by halogen bonding of diazabicyclo[2.2.2]octane, acting as a rotator, and a set of five fluorine-

62 indicated that DABCO (1,4-diazabicyclo[2.2.2]octane) afforded successful conversion of ethyl (E)- and

63 For example, the reaction of n-octane affords up to 86% yield of aromatic product, prim

64 entane triggers assembly, and hexane through octane again does not promote assembly, whereas nonane a

65 ene alkylation gave excellent yields of high octane alkylates (up to RON = 94).

66 In contrast, the lack of water stripping in octane allows efficient hydration of the active site uni

67 o-1,2, 5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane analogues (4a,b and 9a, b) to be the most potent

68 series of 2-carbomethoxy-3-arylbicyclo[3.2.1]octane analogues.

69 ted into 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane and 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane vi

70 decanol, n-octane and n-hexanoic acid, and n-octane and 2-ethylhexyl acetamide.

71 phenyl)-4-n-propyl-2,6,7-trioxabicyclo[2.2.2]octane and [(3)H] 3,3-bis-trifluoromethyl-bicyclo[2,2,1]

72 the bridgehead carbon atoms of bicyclo[2.2.2]octane and all three benzo-annulated bicyclo[2.2.2]octan

73 Stadis-450 and triethylamine mass spectra in octane and discuss issues regarding the use of hydrocarb

74 osphine oxide were measured in mixtures of n-octane and n-decanol, n-octane and n-hexanoic acid, and

75 ow-molecular-mass organogelator (LMOG), in n-octane and n-dodecane have been investigated as their so

76 red in mixtures of n-octane and n-decanol, n-octane and n-hexanoic acid, and n-octane and 2-ethylhexy

77 The early stages of C(60) bombardment of octane and octatetraene crystals are modeled using molec

78 01% of the Rayleigh limit of charge, while n-octane and p-xylene droplets discharge at 87% and 89% of

79 in n-heptane and 17% of the charge in both n-octane and p-xylene.

80 Computations on trans-tricyclo[4.2.0.0(1,3)]octane and spirohexane also were carried out, and the st

81 of 2-carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes and demonstrate that an amino nitrogen is not re

82 -1) for bicyclo[2.2.1]heptane, bicyclo[2.2.2]octane, and adamantane, respectively, were determined in

83 by electrospray ionization from n-heptane, n-octane, and p-xylene doped with Stadis-450, a conductivi

84 ute is not significantly perturbed, even for octane, and the hydrogen bond network is essentially pre

85 microl of 1-pentanethiol and 48 microl of n-octane, and the supernatant is then analyzed via laser-e

86 articularly the 2,3-disubstituted azabicyclo-octanes, appear to be relatively potent antagonists at t

87 re C5+ hydrocarbons and some of these, i.e., octane, are drop-in replacements for existing liquid hyd

88 e as aromatics, 1-octene as an alkene, and n-octane as an alkane.

89 e headspace of the sample using 1.8microL of octane as the extraction solvent.

90 BM-3 variant 9-10A-A328V hydroxylates octane at the 2-position to form S-2-octanol (40% ee).

91 le with SmI2 afforded the 6-azabicyclo[3.2.1]octane B/C-ring system 14, which is a key advanced inter

92 common 1,4-bis(carboxyethynyl)bicyclo[2.2.2]octane (BABCO) functional rotor.

93 1,4-oxazepanes (2,8-dioxa-5-azabicyclo[5.1.0]octanes) based on a domino reaction of fluorinated alpha

94 s and by the sigma-system of a bicyclo[2.2.2]octane (BCO) bridge are presented and discussed.

95 , contains two 1,4-bis(ethynyl)bicyclo[2.2.2]octane (BCO) chiral rotators linked by a diyne fragment

96 nt temperature rotation of the bicyclo[2.2.2]octane (BCO) group in BODCA-MOF constitutes an example w

97 der and relatively cylindrical bicyclo[2.2.2]octane (BCO) rotator linked to mestranol fragments were

98 fur dioxide surrogate 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) (DABSO), is sufficient to ach

99 romethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) (Selectfluor) or N,N-diflu

100 oromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) under mild conditions (tri

101 tene, beta-carotene, lutein, and probucol in octane:butyronitrile (9:1, v/v) were determined to be 1.

102 ard peroxyl radicals in a lipophilic medium (octane:butyronitrile; 9:1, v/v) and dioleoylphosphatidyl

103 Cubane (C(8)H(8), O(h)()) and bicyclo[2.2.2]octane (C(8)H(14), D(3)(h)()) minima are limited to enca

104 DABCO (diazabicyclo[2.2.2]octane) can bind two monomeric porphyrins but was found

105 to afford gamma',delta-bonded bicyclo[2.2.2]octane carbaldehydes 8.

106 s identified on the basis of an azaspiro[2.5]octane carboxamide scaffold.

107 that contains the 1,4-diazoniabicyclo[2.2.2]octane chloride group.

108 iently high stability of 1-borabicyclo[2.2.2]octane complexes for materials applications.

109 The azapalladabicyclo[3.2.1]octane complexes undergo oxidative palladium-carbon bond

110 ions, providing functionalized bicyclo[2.2.2]octane compounds and gamma'-addition products, respectiv

111 g exclusively to the 2, 8-dioxabicyclo[3.2.1]octane core 34; and a novel triple oxidation procedure a

112 R) ligands based on a 3,8-diazabicyclo[4.2.0]octane core have been synthesized and evaluated for affi

113 The bicyclo[4.2.0]octane core of 1 was established by a regio- and diaster

114 elated to the synthesis of the bicyclo[3.2.1]octane core of enterocin by an intramolecular meta-photo

115 ication of the aryl-fused 2-azabicyclo[2.2.2]octane core was achieved by attaching a flexible linker

116 The azabicyclo[2.2.2]octane core was efficiently assembled using a key Vilsme

117 he cis configuration of the azabicyclo[3.3.0]octane core, are prepared in 14 steps from cycloadduct 6

118 ies of compounds is based on a bicyclo[2.2.2]octane core, which is similar in size and polarity to th

119 The isoquinuclidine (2-azabicyclo[2.2.2]octane) core is found in numerous molecules of biologica

120 (from displacement by ethanol) and lower BOB octane could (i) lower refinery CO2 emissions (e.g., app

121 acrylate catalyzed by 1,4-diazabicyclo[2.2.2]octane (DABCO) and a S(N)2' Mitsunobu reaction under the

122 the bidentate ligand 1,4-diazabicyclo[2.2.2.]octane (DABCO) and pi-pi stacking, (Z3PN4)PDI forms a su

123 ing the bicyclic unit 1,4-diazabicyclo[2.2.2]octane (DABCO) and tested their action on three represen

124 Racemic 2,3-diaryl-1,4-diazabicyclo[2.2.2]octane (DABCO) derivatives are synthesized from the read

125 pathways and involves 1,4-diazabicyclo[2.2.2]octane (DABCO) dually as a nucleophilic catalyst, ultima

126 talytic (10-20 mol %) 1,4-diazabicyclo[2.2.2]octane (DABCO) was found to be effective in most cases.

127 cage 3 incorporating 1,4-diazabicyclo[2.2.2]octane (DABCO), an X-ray crystallographic structure was

128 metric base catalyst, 1,4-diazabicyclo[2,2,2]octane (DABCO), and an aqueous medium to overcome proble

129 l (NBA), Trolox (TX), 1,4-diazabicyclo[2.2.2]octane (DABCO), para-nitrobenzoic acid (pNBA), and n-pro

130 etylene halides (TrX) and diazabicyclo[2.2.2]octane (dabco), we were able to distinguish the sources

131 h Cs(+) or protonated 1,4-diazabicyclo[2.2.2]octane (DABCO.H(+)) cations incorporated into deep molec

132 , a bidentate ligand (1,4-diazabicyclo[2.2.2]octane, DABCO), and a viologen-substituted polymer guest

133 esis of enantiopure 1,2-diaminobicyclo[2.2.2]octane (DABO, 1) and its two selectively N-Boc monoprote

134 ad specific activity of up to 5 units/mg for octane-dependent NADPH consumption.

135 f 7-(alkyl or aryl)-6-oxa-2-azabicyclo[3.2.1]octane derivatives from chiral alpha-hydroxyaldehyde der

136 The resultant 8-oxabicyclo[3.2.1]octane derivatives possess a scaffold common in natural

137 ical ring opening, a series of bicyclo[4.2.0]octane derivatives that varied in stereochemistry, subst

138 -bis[6-[[(2-methoxyphenyl)-methyl]hexyl]-1,8-octane] diamine) is an M(2)-selective competitive antago

139 linkers, namely, 1,8-di (3-vinylimidazolium) octane dibromide ([(VIM)(2)C(8)] 2[Br]) and 1,12-di (3-v

140 OF) built with a high-symmetry bicyclo[2.2.2]octane dicarboxylate linker in a Zn4O cubic lattice.

141 solved this challenge with 1,4-bicyclo[2.2.2]octane dicarboxylic acid (BODCA)-MOF, a metal-organic fr

142 netic double-charged diazoniabicyclo [2.2.2] octane dichloride silica hybrid (Fe3O4@SiO2/DABCO) by Au

143 longing to the P-aryl-2-phosphabicyclo[3.3.0]octane family (PBO) has been prepared by enantioselectiv

144 in simulations involving the spreading of an octane film on water, and equilibration of a DPPC bilaye

145 cated that active-site residues constraining octane for omega-hydroxylation are conserved in family 4

146 ibutes to positioning the terminal carbon of octane for omega-hydroxylation.

147 l enamine addition led to 8-oxobicyclo[3.2.1]octane formation, providing evidence for the in situ for

148 the originally proposed cis-azabicyclo[3.3.0]octane fragment with data for natural alkaloids of the p

149 uaternary center and build the bicyclo[3.2.1]octane framework.

150 ariety of 4-substituted trithiabicyclo[2.2.2]octanes from 3-bromo-2,2-bis(bromomethyl)propanol is dev

151 icyclo[2.2.1]heptanes and 8-oxabicyclo[3.2.1]octanes from acetonyl C-glycoside substrates is describe

152 ortant "reforming" reactions to produce high-octane fuels over platinum, were discussed.

153 ers of the 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane (furofuran) lignans from a single dihydrofuran pr

154 in U.S. gasoline, primarily ethanol, a high-octane gasoline component.

155 lytic process in oil refining to obtain high-octane gasoline with minimal content of aromatic compoun

156 increasing polarity of the organic solvent (octane --> tetrahydrofuran --> acetonitrile) the hydrati

157 anti-bromo-4-anti-hydroxy-2-azabicyclo[3.2.1]octane has been reassigned by X-ray analysis.

158 4-position of tetracyclo[3.3.0.0(2,8).0(3,6)]octane has been undertaken.

159 he synthesis of functionalized bicyclo[3.2.1]octanes has been reported, the procedures are relatively

160 h increased levels of autoxidation products (octane, hexanal, C10 hydrocarbons) and other compounds t

161 The bicyclo[4.2.0]octanes hold promise as active functional groups in new

162 l substituted tetracyclo[3.3.0.0(2,8).0(4,6)]octanes (homoquadricyclanes).

163 oxy)methyl]-2-tosyl-6-oxa-2-azabicyclo[3.2.1]octane in a highly diastereoselective manner through an

164 rs between (Cp*d(15))Rh(D)(2)(Bpin)(2) and n-octane, indicating that C-H bond cleavage occurs reversi

165 The structure indicated that octane is bound in a narrow active-site cavity that limi

166 ro-exo,exo-2,6-diaryl-3,7-dioxabicyclo[3.3.0]octanes is described.

167 A series of 8-substituted-3-azabicyclo[3.2.1]octanes (isotropanes) were synthesized and tested for in

168 hosphine ligands: 1,8-bis(diphenylphosphino) octane (L(8) for short).

169 of AOT (Dioctyl sodium sulfosuccinate) in n-octane liquids using small-angle neutron scattering, the

170 a class of cyclobutane bearing bicyclo[4.2.0]octane mechanophores.

171 n also accommodate larger substrates such as octane, methylcubane, and trans-1-methyl-2-phenylcyclopr

172 n performed for 10 keV C60 bombardment of an octane molecular solid at normal incidence.

173 difficult because the nonspherically shaped octane molecule needs a relatively large volume to move

174 OT molecules and their surrounding non-polar octane molecules can hinder heat transfer.

175 analysis of alkanes ( n-hexane, n-heptane, n-octane, n-nonane, n-decane, n-undecane, and n-dodecane)

176 ne pool (currently approximately 93 Research Octane Number (RON)) would enable higher engine efficien

177 isely as desired for increasing the research octane number of gasoline.

178 ume total aromatics target but with a higher octane number.

179 ddition, branched-chain alcohols have higher octane numbers compared with their straight-chain counte

180 ge between (Cp*d(15))Rh(D)(2)(Bpin)(2) and n-octane occurring by dissociation of borane-d(1) to form

181 dues, but they retained high preferences for octane omega-hydroxylation.

182 the relatively rigid 1,4-diazabicyclo[2,2,2]octane, on thermal stability, rigidity upon guest loss,

183 -naphthyl) carbamate (CNC) in an n-alkane (n-octane or n-dodecane) or 3beta-cholesteryl N-(2-naphthyl

184 n 1-vinyl-4-methyl-2,6,7-trioxabicyclo[2.2.2]octane ortho ester.

185 se 143% for xenon, 40% for CEES, and 77% for octane over this pressure range, with maximum peak width

186 tially assembled as a parallel bundle in the octane portion of a phase-separated water/octane system,

187 g a highly diverse range of oxabicyclo[3.2.1]octane products.

188 The sigma-system of bicyclo[2.2.2]octane provides a scaffold having nearly constant bridge

189 ed by simple trituration of the product with octane provides tert-butanesulfinamide with 99% ee and i

190 ons, and crude oil use of increasing average octane rating by increasing (i) the octane rating of ref

191 Three fuels had a constant octane rating of 87 with varied aromatic concentrations

192 average octane rating by increasing (i) the octane rating of refinery-produced hydrocarbon blendstoc

193 Increasing the octane rating of the U.S. gasoline pool (currently appro

194 A fourth fuel with higher octane rating, 91, contained 35% aromatics.

195 discriminant analysis (PLS-DA) according to octane rating.

196 g finished E20 and E30 gasolines with higher octane ratings at modest additional refining cost, for e

197 Higher octane ratings for regular-grade gasoline (with greater

198 ell-to-wheel" analyses of increased gasoline octane ratings in the context of light duty vehicle tran

199 t is one available option for increasing the octane ratings of gasoline and would provide additional

200 concentrations of aromatic hydrocarbons and octane ratings.

201 y response to a significant increase in fuel octane ratings.

202 1,4-hydroxycarbonyls formed from the OH + n-octane reaction in the presence of NO.

203 Treatment with 1,4-diazabicyclo[2.2.2]octane resets the molecular switch.

204 it family 4 enzyme CYP4B1 with its substrate octane reveals that the propensity for omega-hydroxylati

205 an alkynediol to set the dioxabicyclo[3.2.1]octane ring system and a fragmentation of an intermediat

206 this furnished the desired azabicyclo[2.2.2]octane ring system and afforded quincorine (21b), comple

207 .2.1]heptane (tropane) or 8-azabicyclo[3.2.1]octane ring system and have been elaborated into cocaine

208 hly efficient formation of the bicyclo[3.2.1]octane ring system by a reductive radical cyclization.

209 onfiguration of the central azabicyclo[3.3.0]octane ring system of palau'amine and congeners.

210 one-pot procedure to the 8-azabicyclo[3.2.1]octane ring system of the tropane alkaloid ferrugine by

211 boratory to construct the dioxabicyclo[3.2.1]octane ring system, a highly selective aldol fragment co

212 zation favored an undesired azabicyclo[3.2.1]octane ring system, an outcome that was found to be cons

213 yclizations to complete the azabicyclo[2.2.2]octane ring system.

214 plex based on a cis-2,5-diaminobicyclo[2.2.2]octane scaffold catalyzes asymmetric Conia-ene-type cycl

215 or-acceptor cyclopropane-fused benzoxa[3.2.1]octane scaffold with excellent chemo-, regio-, and diast

216 Complex 1a was also especially active in n-octane self-metathesis, providing the highest product co

217 thin the 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane series and for the muscle (alpha1betagammadelta)

218 n-Octane serves as a proximate reservoir supplying O2 to r

219 possible to establish that the bicyclo[2.2.2]octane skeleton present in the lactone-lactam complex st

220 ocyclic systems related to the bicyclo[3.2.1]octane skeleton with replacement of CH(2) at C-2 in bicy

221 Due to the bicyclo[2.2.2]octane skeleton, the steric environment around the carbe

222 yl oleoyl phosphatidylcholine bilayer and an octane slab.

223 the reaction of Re2(CO)10 with Pt(PBut3)2 in octane solvent at reflux.

224 [4 + 2] CA, possessing a diazabicyclo[2.2.2]octane structure; and finally, (iii) an S(N)2 reaction,

225 A series of diazabicyclo[3.3.0]octane substituted pyridines and pyrazines was synthesiz

226 bstituted pyridines or 2-(diazabicyclo[3.3.0]octane)-substituted pyrazines were found to have the des

227 oxamide derivatives of 3-(diazabicyclo[3.3.0]octane)-substituted pyridines or 2-(diazabicyclo[3.3.0]o

228 cids (PFCAs; C6-15) along with six perfluoro-octane sulfonic acid (PFOS) precursors and 11 polyfluoro

229 The octane system has sputtering yield of ~150 nm(3) of whic

230 he octane portion of a phase-separated water/octane system, which provided a membrane-mimetic environ

231 aced by an apramycin-like dioxabicyclo[4.4.0]octane system.

232 d subtilisin BPN' in three organic solvents (octane, tetrahydrofuran, and acetonitrile) and in pure w

233 hesis of polyhydroxylated 2-azabicyclo[3.2.1]octane that can be selectively functionalized.

234 yl-3-(anthracen-9-yl)-2,3-diazabicyclo[2.2.2]octane, that has the hydrazine-to-anthracene charge-tran

235 d at the 8-position of tricyclo[3.2.1.0(2,4)]octane, the 9-position of pentacyclo[4.3.0.0(2,4).0(3,8)

236 lored, which provide access to bicyclo[2.2.2]octanes through a novel mechanistic pathway in high leve

237 d by triethylamine or 1,4-diazabicyclo[2.2.2]octane to produce the one-electron-reduced [Ru(bpy)(2)(p

238 We have transformed a short chain alkane, n-octane, to n-perfluorooctane in stages.

239 The primary objective of the AA5208/OCTANE trial was to compare the efficacy of NVP-based ve

240 lead not only to the expected bicyclo[3.2.1]octane (tropane) ether, imide, and amine derivatives but

241 tion of bridge hydroxylated azabicyclo[3.2.1]octanes (tropanes).

242 The adducts of trithiabicyclo[2.2.2]octane (TTBO) and carbonyl compounds undergo efficient p

243 series of 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane type furofuran lignans have been found in Lactuca

244 rodlike molecules composed of bicyclo[2.2.2]octane units, we studied the effect of interposing a sin

245 oenriched isoquinuclidines and bicyclo[2.2.2]octanes via a p-dodecylphenylsulfonamide-modified prolin

246 rabbit P450 4B1 complexed with its substrate octane was determined by X-ray crystallography to define

247 The reduced plate height, h, for octane was found to be less than 1 at the optimum linear

248 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes was synthesized and tested for inhibitor potency

249 r nitrophenyl octyl ether (1-(2-nitrophenoxy)octane) was studied using cyclic voltammetry and UV-vis

250 udy of the adsorption of two peptides at the octane-water interface.

251 ic and pentameric bundles of VPU(6-27) in an octane/water membrane mimetic system suggested that the

252 ious MD results obtained for VPU(6-27) in an octane/water system.

253 Even for octane we find very little evidence for water-mediated i

254 non, 2-chloroethyl ethyl sulfide (CEES), and octane were acquired with helium buffer gas pressures ra

255 ti-hydroxy-6-syn-I(or Br)-2-azabicyclo[2.2.2]octanes were formed by nucleophilic attack at C(5) on sy

256 Aryl-fused 2-azabicyclo[2.2.2]octanes were prepared by a novel sequence of Cu-catalyze

257 When both O2 and substrate (octane) were added, however, the diferrous cluster was q

258 to form 1,5-disubstituted-6-azabicyclo[3.2.1]octanes with two bridgehead quarternary carbon centers i

259 , we have investigated the class of 1,8-di(R)octanes with various functional groups (R) as processing

260 al anode, allowing internal reforming of iso-octane without coking and yielding stable power densitie

261 e synthesis of P-aryl-2-phosphabicylco[3.3.0]octane x HBF4 salts 3a and 3c is described.

262 ve, TABO (1,3,3-trimethyl-6-azabicyclo[3.2.1]octane), yielding 1,8-naphthyridines with as high as 96:

263 8-hetero-2-carbomethoxy-3-arylbicyclo[3.2.1]octanes yields potent inhibitors of monoamine transport.