ライフサイエンスコーパス: ocular lens

1 heir independent existence in the developing ocular lens.

2 alphaB exist as independent proteins in the ocular lens.

3 n and Parkinson disease are expressed in the ocular lens.

4 d from cells in the center of the developing ocular lens.

5 tations in the alphaA-crystallin gene of the ocular lens.

6 pecification and subsequent formation of the ocular lens.

7 (CNS), peripheral nervous system (PNS), and ocular lens.

8 , MAGI3, and MPDZ are expressed in the mouse ocular lens.

9 l and peripheral nervous systems, liver, and ocular lens.

10 E interactions by postnatal day 10-21 in the ocular lens.

11 ak), homozygotes of which fail to develop an ocular lens.

12 chaperone the transparency properties of the ocular lens.

13 imeric protein, alpha-crystallin, within the ocular lens.

14 uses a subtle loss of optical clarity in the ocular lens, a loss that worsens with age.

15 alpha-Crystallin, the major protein of the ocular lens, acts as a molecular chaperone by suppressin

16 One of the major protein components of the ocular lens, alpha-crystallin, is composed of alphaA and

17 ive and inducible expression of ICSBP in the ocular lens and differential regulation of its subcellul

18 specifically expressed in fiber cells of the ocular lens and expression is regulated temporally and s

19 lins comprise 35% of soluble proteins in the ocular lens and possess chaperone-like functions.

20 of alphaB-crystallin within and outside the ocular lens and suggest that non-crystallin/catalytic fu

21 Cx50 expression was limited to the ocular lens and was not detected in either the cornea or

22 ng tissues, such as the embryonic muscle and ocular lens, and in human leukemia HL60 cells induced to

23 proximal aortic aneurysm, dislocation of the ocular lens, and long-bone overgrowth.

24 on detected in the stomach, urinary bladder, ocular lens, and lung.

25 ck of protein turnover in fiber cells of the ocular lens, Aquaporin 0 (AQP0), the most abundant membr

26 Using the ocular lens as a model system, we demonstrate that diffe

27 s a major structural protein (22 kDa) of the ocular lens as well as a bona fide heat shock protein in

28 The fiber cell of the vertebrate ocular lens assembles a cytoskeletal structure, the bead

29 om specific locations in three tissue types; ocular lens, brain, and kidney.

30 cause of its constant exposure to light, the ocular lens continuously generates reactive oxygen speci

31 Morphogenesis and shape of the ocular lens depend on epithelial cell elongation and dif

32 Transparency of the ocular lens depends on symmetric packing and membrane or

33 Ocular lens development represents an advantageous syste

34 The three connexins expressed in the ocular lens each contain PDZ domain-binding motifs direc

35 The molecular structure of human ocular lens fiber cell plasma membranes was examined dir

36 domains within the plasma membranes of human ocular lens fiber cells.

37 During mammalian embryogenesis, the ocular lens forms through a temporally and spatially reg

38 In the ocular lens, gap junctional communication is a key compo

39 mentation of the antioxidant defenses of the ocular lens has been shown to prevent or delay cataracto

40 Outside of the ocular lens, however, alphaA and alphaB are known to be

41 the differentiating, or fiber, cells of the ocular lenses in transgenic mice.

42 In the ocular lens, inactivation of this protein is sufficient

43 The ocular lens is a classical model system to study tissue

44 The ocular lens is a model system for understanding importan

45 The vertebrate ocular lens is a simple and continuously growing tissue.

46 The refractivity and transparency of the ocular lens is dependent on the stability and solubility

47 The ocular lens is routinely assaulted by UV light that caus

48 The ocular lens is the only organ that does not develop spon

49 Ocular lens morphogenesis is a model for investigating m

50 s to the high expression of many crys in the ocular lens of diverse species.

51 OCT images are concurrently displayed on the ocular lens of the microscope.

52 ression of a self-activating TGFbeta1 in the ocular lens of transgenic mice results in inhibition of

53 sidues of the gamma crystallins, a family of ocular lens proteins, are involved in the aggregation an

54 and ERK2 are the most abundant MAPKs in the ocular lens, providing the basis for their multiple func

55 emonstrating that in the center of the human ocular lens, there is no lipid turnover in fiber cells d

56 ha)) or epidermal growth factor (EGF) in the ocular lens using the mouse (alpha)A-crystallin promoter

57 The image formed by the ocular lens was examined in intact fish made transparent

58 heat shock protein (and a crystallin) in the ocular lens, was investigated.

59 partners for alpha-crystallin in the intact ocular lens, we conducted cross-linking studies in trans