ライフサイエンスコーパス: ocular tissue

1 rejection without inducing damage to normal ocular tissue.

2 the mouse genital tract and nonhuman primate ocular tissue.

3 eceptor ligand (GITRL) and its regulation by ocular tissue.

4 necrosis were histologically evident within ocular tissue.

5 ing genes in cultured cells and in vivo into ocular tissue.

6 tative analysis of mucin expression in human ocular tissue.

7 ivated protease IV (200 ng) had no effect on ocular tissue.

8 nd modulating inflammation and thrombosis in ocular tissue.

9 during degeneration of post-mitotic cells of ocular tissue.

10 Rs) are expressed in leukocytes and in every ocular tissue.

11 with those of whole embryo body (WB) lacking ocular tissue.

12 s confirmed by immunohistochemistry on human ocular tissue.

13 ns of these two ocular pigments in serum and ocular tissues.

14 space resulted in high levels of CsA in most ocular tissues.

15 that have previously been identified in the ocular tissues.

16 hat occur as primary and secondary tumors in ocular tissues.

17 asma lipoprotein origin accumulated in other ocular tissues.

18 corneal stroma and endothelium nor in other ocular tissues.

19 erformed to validate TGIF gene expression in ocular tissues.

20 gents also provide improved penetration into ocular tissues.

21 d CD63 was conducted on control and inflamed ocular tissues.

22 ed budesonide levels in the retina and other ocular tissues.

23 to other barrier epithelia are expressed in ocular tissues.

24 25 hours postinfection (PI), as measured in ocular tissues.

25 roxidase (MPO) and PLA(2) were quantified in ocular tissues.

26 inflammatory eye disease that affected most ocular tissues.

27 omolog 1 (Siah1), was recently identified in ocular tissues.

28 that negatively regulate vascular growth in ocular tissues.

29 their roles in normal, damaged, and diseased ocular tissues.

30 that TGFbeta1 can substitute for TGFbeta2 in ocular tissues.

31 r and SSTR2-ir were observed in all analyzed ocular tissues.

32 antibodies resulted in disruption of ventral ocular tissues.

33 oids at a prereceptor level in human and rat ocular tissues.

34 appears to be present in low amounts in non-ocular tissues.

35 detected in embryonic craniofacial and adult ocular tissues.

36 o examine OA transporter expression in human ocular tissues.

37 agnostic tool for high-resolution imaging of ocular tissues.

38 gated whether TTase is also present in other ocular tissues.

39 death caused a fourfold elevation of ET-1 in ocular tissues.

40 with the 2.4-kilobase transcript enriched in ocular tissues.

41 scale sequencing of cDNAs derived from human ocular tissues.

42 e trabecular meshwork, optic nerve and other ocular tissues.

43 tive peptides that are widely distributed in ocular tissues.

44 cted to the lens, apply to other transparent ocular tissues.

45 as a model for the use of vitamin E by human ocular tissues.

46 ajor ALDH1 transcript in both ocular and non-ocular tissues.

47 oprotein that is expressed in ocular and non-ocular tissues.

48 d by anticancer agents are also expressed in ocular tissues.

49 TM and CNTNAP4 were shown to be expressed in ocular tissues.

50 le-body autoradiography and radioanalysis of ocular tissues.

51 d, high-resolution cross-sectional images of ocular tissues.

52 l vectors with limited effect on surrounding ocular tissues.

53 n an imbalance of VEGF-A and sVR-1 levels in ocular tissues.

54 lates in the human plasma, major organs, and ocular tissues.

55 ual Noggin producing, MyoD-positive cells in ocular tissues.

56 ession of PD-L2 on either normal or inflamed ocular tissues.

57 The FcRn receptor is expressed in multiple ocular tissues.

58 ize the distribution of the FcRn receptor in ocular tissues.

59 hus coordinating the patterning of these two ocular tissues.

60 e diffusion studies of different analytes in ocular tissues.

61 e marrow derived and have a slow turnover in ocular tissues (3-6 months).

62 ave shown a mechanism for HTRA1 to instigate ocular tissue abnormalities.

63 lial cells and PDGF (A- and B-chains) in the ocular tissues adjacent to the lens suggests that PDGF s

64 The ocular tissue affected by JXG included the iris (21/31,

65 These results document the first ocular tissue affected by Pitx2 gene dose in a model org

66 d epithelial (RPE) layer is one of the major ocular tissues affected by oxidative stress and is known

67 neither lack of Fas nor lack of FasL on the ocular tissues affected expression of EAU.

68 There was no permanent histologic damage to ocular tissue after the inflammation cleared in these an

69 humanized model of MAC deposition on murine ocular tissues allows testing of human complement regula

70 ssion and release of inflammatory markers in ocular tissues, along with the attenuation of NF-kappaB

71 Previous studies have shown that ocular tissue also expresses functional Fas ligand (FasL

72 ly retaining the ability to replicate within ocular tissue and allowing the eye to serve as a portal

73 h) has been implicated in both patterning of ocular tissue and direct guidance of RGC axons.

74 This takes place within the ocular tissue and is supported by retinoic acid, which i

75 his study was to evaluate CMV persistence in ocular tissue and to determine the potential for reactiv

76 MF is rare, but the involvement of different ocular tissues and a highly variable clinical presentati

77 These proteins interact with each other in ocular tissues and also in a heterologous system.

78 integrity and relax resistance arterioles in ocular tissues and brain through a mechanism involving a

79 In addition to ocular tissues and cartilage, opticin mRNA and protein h

80 FKN is expressed in various ocular tissues and cells.

81 Pharmacokinetic distribution in all ocular tissues and fluids was studied at 0.5, 1, 2, 4, 6

82 lls are present in diabetic fibrocontractive ocular tissues and generate tractional forces in respons

83 py treatments with less collateral damage to ocular tissues and may allow reduced systemic dosage and

84 tern blot analyses of proteins from cultured ocular tissues and microdissected outer and inner retina

85 Both ocular tissues and systemic organs (brain, liver, kidney

86 type XVIII collagen is broadly expressed in ocular tissues and that it may have a role in wound heal

87 ce support greater replication and spread in ocular tissues and the nervous system.

88 melatonin receptor subtype proteins in chick ocular tissues and to examine the role of the circadian

89 support the existence of the drug target in ocular tissues and via a PPARalpha-dependent mechanism.

90 TTase was found in most ocular tissues and was concentrated in the anterior segm

91 lasts (HCF) stimulated with TGF-beta, normal ocular tissues and wounded corneas.

92 ntly identified in diabetic fibrocontractive ocular tissues and, in response to insulin-like growth f

93 t tissues of the adult human body, including ocular tissues, and a comparison of expression data with

94 ngiogenic factors in the anterior surface of ocular tissues, and analyzed the mitogenic and angiogeni

95 the increase in vascular conductance in all ocular tissues, and blocked the decrease in mean arteria

96 trum of activity, increased penetration into ocular tissues, and delayed propensity to the developmen

97 tered parasites in the retina, in nonretinal ocular tissues, and in the brain.

98 tion of EP(1) and FP receptor mRNAs in human ocular tissues appears to be localized in the functional

99 notypes raise the possibility that different ocular tissues are differently sensitive to specific mut

100 fication of analytes transport in epithelial ocular tissues are extremely important for therapy and d

101 Ocular tissues are protected by the blood-ocular barrier

102 from the posterior segment of the eye, that ocular tissues are rich in bone marrow-derived LYVE-1(+)

103 that chrdl1 is specifically expressed in the ocular tissue at late developmental stages.

104 teins have been identified in high levels in ocular tissues, but no experimental model is available f

105 plice sites of AF-6 were identified in chick ocular tissues, but only two were expressed in RPE.

106 on, expression of alpha-MSH was evaluated in ocular tissue by immunocytochemistry.

107 ELOVL4 protein is evident in the ocular tissues by E10.5 and becomes restricted predomina

108 ity and blood flow, respectively, induced in ocular tissues by IV infusion of recombinant human VEGF1

109 Plasma and ocular tissue carotenoid analyses, fundus photography, a

110 was to quantify the morphological changes of ocular tissues caused by formalin fixation and cryosecti

111 usion, we found that mitotically incompetent ocular tissue cells contain adult NCDPs that exhibit a p

112 ical regulator of the developing lens, other ocular tissues, central nervous system, and pancreas.

113 In ocular tissue, CFH was detected in the distalmost optic

114 expressed in the iris and ciliary body, the ocular tissues closest to the germinative zone of the le

115 Extension of this approach to other ocular tissue components will facilitate eye disease gen

116 er the superior conjunctiva bilaterally, and ocular tissue concentration was determined using Western

117 ith L and/or Z increased the mean plasma and ocular tissue concentrations of these carotenoids and th

118 pidly growing fetal relative to normal adult ocular tissue (confirmed by RT-qPCR).

119 mouse, rat, and rabbit whole eyes and rabbit ocular tissues contained abundant amounts of C-terminal

120 consists of highly organized and specialized ocular tissues critical for normal vision.

121 Also, apparently viable organisms persist in ocular tissues despite prolonged exposure to antifungal

122 that human fibroblasts derived from distinct ocular tissues differ in their responses to IL-1beta and

123 More importantly, ocular tissue displays functional TRAIL as determined by

124 These compounds demonstrate preferential ocular tissue distribution and efficacy after oral admin

125 tment of leukocytes to the immune-privileged ocular tissues during acute inflammation.

126 of CFH expression is maintained in different ocular tissues during development and aging.

127 nt expression of endogenous keratocan in non-ocular tissues during embryonic development was confirme

128 al Wnt signaling components are expressed in ocular tissues during eye development including Dkk2, en

129 Ocular tissue ET-3 levels were unaffected by diabetes.

130 E-lycopene were detected in nearly all human ocular tissues examined.

131 ributed as single cells, was detected in all ocular tissues except the central cornea.

132 Ocular tissue flatmounts from normal or enhanced green f

133 subjects without AMD (controls), as well as ocular tissue from 40 pathological sections with AMD and

134 Ocular tissue from diabetic patients shows PAR-2 colocal

135 a v beta 3 and alpha v beta 5 in neovascular ocular tissue from patients with subretinal neovasculari

136 isease similar to that observed in diabetes, ocular tissue from transgenic mice that overexpress huma

137 We analyzed ocular tissues from abcr(-/-) mice for A2E oxiranes by m

138 Here, we identify three precursors of A2E in ocular tissues from abcr-/- mice and humans with ABCR-me

139 P) protein adducts that are more abundant in ocular tissues from AMD than normal human donors.

140 barrier and the ocular environment protects ocular tissues from autoimmune attack.

141 Ocular tissues from five time points (1, 3, 7, 14, and 3

142 r techniques in the diagnostic evaluation of ocular tissues from HTLV-1 patients, and clinical studie

143 on that may have evolved to protect delicate ocular tissues from immune-mediated damage.

144 Ocular tissues from rhesus monkeys (Macaca mulatta) were

145 Comparison of ocular tissues from seven subjects revealed no heterogen

146 ead, aqueous humor partially protected these ocular tissues from starvation-induced cell death.

147 Ocular tissues from these animals were also evaluated fo

148 ion of the laser, its biophysical effects on ocular tissues from which it derives its name (light-amp

149 Each of the ocular tissues had distinctive patterns of Hsp25 and -90

150 l activity was transiently found in some non-ocular tissues, i.e. ears, snout, and limbs of embryos o

151 , based on DNaseI hypersensitivity data from ocular tissue in the ENCODE project.

152 on of melatonin alters the growth of several ocular tissues in both control and form-deprived eyes su

153 Histopathology showed normal ocular tissues in both dogs and rabbits 6 months after i

154 tologic evidence of immune cell reduction in ocular tissues in corticosteroid-treated eyes implies a

155 unoblot analysis and to cryostat sections of ocular tissues in immunofluorescence studies.

156 that PEDF transcripts are present in all the ocular tissues in the human eye; in the bovine eye, it i

157 293F cells and as a major band of 150 kDa in ocular tissues including ciliary body, sclera, cornea, a

158 of MAC deposition on murine cells and murine ocular tissues including RPE and cornea was developed to

159 cular region and later contribute to various ocular tissues including the cornea, ciliary body and ir

160 or proper differentiation of the surrounding ocular tissues including the cornea, iris and ciliary bo

161 ne, myocilin, is expressed in ocular and non-ocular tissues including the peripheral nervous system,

162 des were efficiently distributed to numerous ocular tissues, including retina, ciliary body, and opti

163 changes in the trabecular meshwork (TM), an ocular tissue involved in regulating IOP, which can lead

164 The ocular tissues involved in the phenotype are the retinal

165 mRNA was isolated from human ocular tissues (iris/ciliary body, retina, and choroid)

166 The presence of eosinophilic granulocytes in ocular tissue is a hallmark of the host response to envi

167 The most commonly involved ocular tissue is the eyelid skin, but intraocular involv

168 To determine how HNE is detoxified in ocular tissues, its metabolism in cultured human lens ep

169 The results show that ocular tissue kills via either ligand, suggesting a comp

170 Also in contrast to the skin, pigmented ocular tissue lacked expression of the alpha-MSH ligand,

171 aucoma suggests increased viscoelasticity of ocular tissues may have a protective role against glauco

172 ), that are specifically concentrated within ocular tissues, may play important roles in maintaining

173 mice suggest that control of MCMV latency in ocular tissue might involve other regulatory events that

174 cryosectioning are good choices for studying ocular tissue morphology and structure, as they do not c

175 f a fibrillar extracellular material in many ocular tissues, most commonly seen on the pupillary bord

176 In the rat ocular tissues mRNAs encoding glucocorticoid receptor, m

177 Outcome data were collected from the UK Ocular Tissue National Transplant database and supplemen

178 Paraffin sections of human ocular tissues obtained after death were analyzed by imm

179 and eye and a higher level of nitrite in the ocular tissue of mutant strains than in the wild type.

180 kines IL1beta and IFNgamma was quantified in ocular tissues of aire-deficient mice and patients with

181 Melanin content in ocular tissues of both the strains was determined by sod

182 In ocular tissues of healthy house finches, we identified 5

183 regulated by all-trans-retinoic acid in non-ocular tissues of mice.

184 ET-3 were determined by radioimmunoassay in ocular tissues of normal rats, and in rats with streptoz

185 sion of IL1beta and IFNgamma was elevated in ocular tissues of patients with SS and aire-deficient mi

186 es are expressed in retinal and extraretinal ocular tissues of the chick eye.

187 els were detected in the normal vascularized ocular tissues of the monkey: the conjunctiva, iris, ret

188 n A contact lens is beneficial in protecting ocular tissues of the rabbit against the harmful effects

189 o protect against UVB-induced effects on the ocular tissues of the rabbit in vivo.

190 The mean levels of L and Z in plasma and ocular tissues of the rhesus monkeys increase with suppl

191 ting through specific melatonin receptors in ocular tissues, plays a role in ocular growth and develo

192 Epigenetic regulatory mechanisms in ocular tissues represent exciting areas of research that

193 disease and the number of genes expressed in ocular tissue residing on the X-chromosome.

194 Immunocytochemical analysis of chick ocular tissues revealed the cellular distribution of the

195 from June 19, 2015, through April 30, 2017, ocular tissue samples from 4 deceased fetuses with a dia

196 Ocular tissue samples from the 4 deceased fetuses (2 fem

197 DNA libraries from fetal and adult brain and ocular tissue samples were generated and used for candid

198 ug was administered, and celecoxib levels in ocular tissues (sclera, choroid-RPE, retina, vitreous, l

199 Human ocular tissue sections from patients with geographic atr

200 Immunohistochemical studies of ocular tissue showed a specific AnxA1 posttranslational

201 abcr accumulate toxic lipofuscin pigments in ocular tissues, similar to affected humans.

202 ced expression patterns of genes involved in ocular tissue specification (Pax6, Pax2, and Otx2) and d

203 role of CpG methylation in the regulation of ocular tissue-specification and described hypermethylati

204 is a retinol dehydrogenase expressed in non-ocular tissues such as the liver and testis and in the r

205 By contrast, ocular tissues, such as the corneal endothelium and iris

206 Moreover, expression data from ocular tissue support the role of these CNV-implicated g

207 Murine PE cells cultured from different ocular tissues suppress T cell activation by differing m

208 retain HA in the articular joint and to bind ocular tissue surfaces.

209 The TMEM98 gene was expressed in all ocular tissues tested including sclera and optic nerve h

210 Among all the ocular tissues tested, iris showed the highest TTase act

211 with AP-2alpha expressed in a number of the ocular tissues that exhibited defects in the mutants, in

212 iven that Bves has been reported in multiple ocular tissues, the authors hypothesize that Bves plays

213 as and FasL expression on lymphocytes and on ocular tissues, the occurrence of apoptosis, and the fre

214 orescence microscopy were performed on human ocular tissue to examine the in vivo protein expression

215 CFH gene and localization of this protein in ocular tissues to gain insight into its role in the eye.

216 pression, indicating that IgG transport from ocular tissues to the blood system may use this receptor

217 Thus, our results suggest that various ocular tissues up-regulate the expression of Crry and CD

218 ected and quantitated labeled carotenoids in ocular tissue using both HPLC-coupled mass spectrometry

219 Ocular tissue was analyzed histologically and in retinal

220 Microdissected eye-bank ocular tissue was characterized by western blot analysis

221 Ocular tissue was obtained from 1 patient at autopsy.

222 Plaque assay of homogenized ocular tissue was used to determine the frequency of vir

223 expression pattern of the candidate gene in ocular tissues was analyzed by reverse transcriptase-pol

224 The drug toxicity in the ocular tissues was assessed by histopathology and high-r

225 Specificity of the antibody to MMP-1 in ocular tissues was confirmed by western blot analysis wi

226 Distribution of ADM in the ocular tissues was determined by RIA.

227 , and Mel(1c) melatonin receptor proteins in ocular tissues was examined by Western blot analyses, sl

228 presence of this enzyme transcript in these ocular tissues was further confirmed by the positive slo

229 uctural organization of the retina and other ocular tissues was maintained in all experimental condit

230 Delayed appearance of macrophages in ocular tissues was observed in Tgfb2(-/-) mice.

231 ver, in situ expression of PD-L1 in inflamed ocular tissues was remarkably upregulated compared with

232 Apoptosis of inflammatory cells and cells in ocular tissues was seen, and a greater frequency of CD8(

233 To study virus-host interactions in ocular tissue, we infected primary human corneal and con

234 Single-cell suspensions from ocular tissues were also prepared and were analyzed by f

235 Ocular tissues were analyzed by immunohistology, and ser

236 Drug levels in various ocular tissues were analyzed by liquid chromatography-ta

237 s of various adrenergic antagonists in these ocular tissues were compared with their affinities for t

238 ear factor kappa B (NF-kappaB) expression in ocular tissues were determined immunohistochemically.

239 The drug affinities in all four human ocular tissues were highly correlated (correlation coeff

240 om nondiabetic rats and separated from other ocular tissues were incubated for several hours in incub

241 Ocular tissues were obtained from 58 dogs with mucopolys

242 Ocular tissues were obtained from six aged control donor

243 18 concentration time profiles in plasma and ocular tissues were quantified by liquid scintillation c

244 properties of small specimens of orbital and ocular tissues were reliably characterized over a wide r

245 Total RNA extracted from human and bovine ocular tissues were screened by Northern blot analysis w

246 id absorption, and transport from serum into ocular tissues were similar to results observed in most

247 The carotenoid profiles in quail and frog ocular tissues were somewhat similar to those in humans,

248 Parabulbar and ocular tissues were studied by light microscopy for evid

249 at these receptors are present in mammalian ocular tissues, which regulate aqueous humor formation a

250 AC-II and AC-IV were characterized in ocular tissue with reverse transcription-polymerase chai

251 ha v beta 3 was observed on blood vessels in ocular tissues with active neovascularization from patie

252 al drops the exposure was minimal in all the ocular tissues with greater systemic exposure.

253 f type XVIII collagen was performed in mouse ocular tissue, with polyclonal antibodies to the hinge d

254 ectioning caused only minimal changes to the ocular tissues, with average percentage parameter differ

255 abeled AMG 386 was widely distributed across ocular tissues, with highest concentrations in the choro

256 odifying the refractive index of transparent ocular tissues without apparent tissue destruction.