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1 argeted therapies are performed increasingly often.

2 ion of public goods in biological systems is often a collaborative effort that may be detrimental to

3 terdependencies, while network centrality is often a good indicator of importance.

4 y shaped by competing phases whose nature is often a mystery.

5 nfancy with pharmaco-resistant seizures; are often accompanied by debilitating neuropsychiatric and s

6 Type 2 diabetes is often accompanied by dyslipidemia with elevated levels o

7 ange dramatically during the ageing process, often accompanied by major increases in pathogen suscept

8 Subcortical white matter injury is often accompanied by orofacial motor dysfunction, but li

9 Malignant transformation is often accompanied by significant metabolic changes.

10 ions of the central nervous system (CNS) are often acute, with significant morbidity and mortality.

11 This protein modification is often added by ADP-ribosyltransferases, commonly known a

12 al cause of visual impairment and blindness, often affecting marginalized populations.

13 st commonly in the first five years of life, often after the first known ingestion with typical rapid

14 Adolescents with ADHD get licensed less often and at an older age.

15 in dementia as appropriate or inappropriate often applied in institutional settings, fails to accoun

16 Purpose Men with localized prostate cancer often are treated with external radiotherapy (RT) over 8

17 Since whole cell responses most often arise from the coordinated activity of multiple SC

18 ntions are successful, resistance to therapy often arises.

19 Decision-makers often arrive at different choices when faced with repeat

20 causal in 20% of MI cases and presented more often as ST-segment elevation MI versus MI not related t

21 ption factor (TF) binding of cis-elements is often associated with accessible chromatin regions.

22 or prognosis hepatocellular carcinoma (HCC), often associated with chronic hepatitis B virus (HBV) in

23 These demographic fluctuations are often associated with concurrent changes in the average

24 These fossils are often associated with iron-rich sedimentary rocks, but t

25 h distinct sequences in both species and are often associated with motifs involved in the Nrd1-Nab3-S

26 are important causes of plant-food allergies often associated with severe allergic reactions.

27 a common cause of pain and disability and is often associated with the degeneration of articular cart

28 The dental follicle (DF), most often associated with unerupted teeth, is a condensation

29 learning models of the ventral striatum (VS) often assume that it maintains an estimate of state valu

30 o determine evolutionary trajectories and is often assumed to be static and independent of the actual

31 Antisocial behavior is often assumed to reflect aberrant risk processing.

32 tis in pediatric HSCT patients in the early, often asymptomatic stage.

33 tract disease, characterized by persistent, often asymptomatic, infection.

34 that policies in Malaysia and Indonesia are often based around the narrative of oil palm and other m

35 reas iconic enrichments in sign language can often be at-issue.

36 Complex economic systems can often be described by a network, with nodes representing

37 Similarly, the treatment must often be tailored to each patient by targeting the speci

38 These inflammatory responses often become chronic and non-resolving and can lead to a

39 Also, the schooling pattern has often been associated with an advantage in terms of ener

40 Achieving this has often been hampered by the relative lack of information

41 (TAD) borders, while dCP enhancers are more often bound to one or two TSSs and are enriched at chrom

42 plications make simplifying assumptions that often break up the dependency between the four processes

43 Self-reported tiredness and low energy, often called fatigue, are associated with poorer physica

44 s are organized in clusters, the latter ones often called lipid domains or "lipid rafts." Recent find

45 Invaded species often can rapidly expand and establish in novel environm

46 Plants respond to hypoxia, often caused by submergence, by expressing a specific se

47 serious health problem around the world and often causes fibrosis/cirrhosis and hepatocellular carci

48 component of skin flora, is an opportunist, often causing prosthetic device infections.

49 S. aureus toxins and virulence proteases often circulate in host blood vessels leading to life-th

50 s multiple sites of phosphorylation that are often clustered, where kinases work together in a hierar

51 dies indicate that the master regulators are often coexpressed.

52 Posttraumatic stress disorder is often comorbid with MDD, and symptoms of both disorders

53 guidelines can take into account all of the often compelling unique individual clinical circumstance

54 being increasingly performed; yet, there is often confusion regarding indications, outcomes, and how

55 n women without obstructive CAD, a condition often considered benign and without guideline-recommende

56 information on three important minor metals often considered critical.

57 They are often considered to be a reliable source of evidence for

58 icularly those with elastolytic ability, are often considered to be key drivers in this disease.

59 at the contents of human episodic memory are often constructed in the service of the explicit justifi

60 Elimination of this often contentious distinction would improve both the cul

61 Layered Mn oxide minerals (phyllomanganates) often control trace metal fate in natural systems.

62 patterning (i.e., spacing distance, density) often controlled by limiting resources.

63 nsistent offsets in space and in time, which often defy traditional mechanistic explanations.

64 Liver R2* mapping is often degraded by the low signal-to-noise ratio (SNR) es

65 CV) infection, because of cost, treatment is often denied until liver fibrosis has progressed to at l

66 radiation damage in ion-irradiated crystals often depends on the spatial distribution of atomic disp

67 Although often described as a childhood disease, newer population

68 improve sensitivity, multiple pathogens are often detected and this adds complexity to the interpret

69 Breast cancer cells often develop resistance to endocrine therapy via restor

70 Sex chromosomes often differ between closely related species and can eve

71 ctions associated with biofilm formation are often difficult to resolve without extended courses of a

72 lk, weight, and wireless area of coverage is often disadvantageous.

73 ency (W i ) reconstructions using tree rings often disregard developmental changes in W i as trees ag

74 Structural defects often dominate the electronic- and thermal-transport pro

75 aracterizes a variety of skeletal dysplasias often due to interacting or overlapping signaling pathwa

76 nhibitors (CKIs), the expression of which is often dysregulated in cancer cells.

77 sex that experiences haploid selection most often (e.g., pollen beneficial alleles become strongly a

78 t hematologic neoplasms, malignant cells are often easily accessible in the blood as circulating tumo

79 of disease has been explored, but they were often ecological in design, used broad census geographic

80 r loss from chemotherapy and radiotherapy is often encountered in cancer treatment, and there is a la

81 cificity and disease-associated variants are often enriched for CREs in the tissues and cells that pe

82 Individuals with cerebral palsy often exhibit crouch gait, a debilitating and inefficien

83 Patients with lung or colorectal cancer often exhibit leukocytosis.

84 As a result, fast animals often exhibit optical adaptations comparable to nocturna

85 their narrative, aggressive in behavior, and often exhibit questionable moral character.

86 Microbial species often exist in complex communities where they must avoid

87 lly sparing the foveal center, and over time often expand and coalesce to include the fovea.

88 monitoring of hydrocarbon (HC) pollution is often expensive and time-consuming.

89 ve capacity of muscles in these patients who often experience cachexia.

90 Under these conditions, different cells often experience diverse stimulus time courses, which is

91 DLBCL in the clinic; however, [(18)F]FDG-PET often faces difficulty in differentiating malignant tiss

92 f-building coral health into the future, but often fail to account for the complex ecological and bio

93 onal optical, X-ray and photoelectron probes often fail to provide interface-specific information in

94 Preclinical animal testing often fails to predict adverse outcomes arising from seq

95 er, recent research suggests that extinction often fails to reduce fear when administered soon after

96 It is a common, serious, and often fatal condition among older patients.

97 also attack host normal tissues through the often fatal graft-versus-host disease (GVHD).

98 Compared with non-CF, MUC5B more often filled CF submucosal gland ducts.

99 New studies, often focusing on the regulation of chromosomal proteins

100 e ice shelves, we have discovered that ponds often form part of widespread, large-scale surface drain

101 The same PAINS substructure was often found in consistently inactive and frequently acti

102 particular, branched chain AAs (BCAAs), are often found increased in nonalcoholic fatty liver diseas

103 , where constitutive NF-kappaB activation is often found to promote the expression of various protein

104 During development, cell division often generates two daughters with different development

105 The dynamics of chemical reactions are often governed by transient species, including the trans

106 Differences in efficacy between drugs were often greater than the difference in efficacy between tr

107 out individuals in our social network, which often guide our decisions as we navigate complex social

108 s with HF were elderly (mean age, 71 years), often had comorbid conditions, and 16% had difficulty wi

109 dical group (vs the conservative group) more often had multifocal disease (80% vs 56%, P = 0.04), che

110 es have large foraging ranges and their prey often have a patchy distribution.

111 a mineral-organic C interactions but Oxisols often have low organic C.

112 ontaneous urticaria (CSU) are widely held to often have other autoimmune disorders, including autoimm

113 sites, dimer interface or selectivity filter often have severe functional consequences.

114 ng molecules that are mutated in cancers can often have substantial short-term effects, but the emerg

115 the question, 'Over the last two weeks, how often have you felt tired or had little energy?' Univari

116 y large molecular sequence datasets that are often heavily partitioned in order to accurately model t

117 d groups tend to be at least moderately, and often highly accurate.

118 the form of short reads, yielding discrete, often highly non-normally distributed gene expression me

119 DNA/RNA viruses often hijack the cellular factors resident in PML-NBs to

120 The synthesis of complex oligosaccharides is often hindered by a lack of knowledge on the reactivity

121 se relationships; however, these factors are often ignored in environmental epidemiology studies.

122 ly critical, because while chronic stress is often immunosuppressive, acute stress can temporarily en

123 in all major classes of natural products and often impart significant biological activity.

124 In simulations, the dry run often improved assessment of confounding control, compar

125 enotype classes in the epistatic networks is often improved by accounting for the interactions.

126 g pharmacogenomic markers with TF activities often improves the stratification of cell lines in respo

127 l information from groups of similar objects-often in a brief glance.

128 eve gastrectomy (LSG) is performed almost as often in Europe as laparoscopic Roux-Y-Gastric Bypass (L

129 patients with BCR, and changes occurred more often in patients with radical radiotherapy treatment, p

130 s, quality assurance, staffing and training, often in resource-limited settings.

131 d, (2) why shamanism professionalizes early, often in the absence of other specialization, and (3) ho

132 h some specific adverse events occurred more often in the intensive group.

133 However, these strategies are often inadequate to detect bacterial infection and are n

134 s of GSK3 activity for axon regeneration are often inconsistent, if not controversial.

135 such as proteomics and metabolomics, are now often incorporated into the everyday methodology of biol

136 Atypical antipsychotics such as olanzapine often induce excessive weight gain and type 2 diabetes.

137 important for viral clearance, and although often ineffective in neonates they can be protective whe

138 ogical parameters for livestock diseases are often inferred from transmission experiments.

139 occur at low frequencies, such that there is often insufficient statistics for downstream calculation

140 The northward-flowing Kuroshio often intrudes westward and modulates the water masses o

141 s in marine environments remain challenging, often invasive and resource-intensive.

142 Such states are often invoked in the excited-state dynamics of donor-acc

143 Life-critical perceptual decisions often involve searching large image data (e.g., medical,

144 with unprovoked venous thromboembolism (VTE) often is considered, but clinicians need precise data on

145 Strong-field laser-matter interactions often lead to exotic chemical reactions.

146 nce of these drugs residues in honey as they often lead to health concerns or potential antibiotic re

147 Influenza viral infections often lead to increased mortality in older people.

148 somewhat disappointing body weight changes, often leading to the hormone/mediator in question being

149 rly detection of metastatic infectious foci, often leading to treatment modification.

150 Such sensory weighting often leads to a dominance of a certain sense during par

151 Neuronal injury often leads to devastating consequences such as loss of

152 The resultant antagonistic coevolution often leads to extreme adaptations in both parties.

153 Expression of membrane proteins often leads to growth inhibition and perturbs central me

154 concerns and other logistical considerations often limit access to individual-level genetic data, mot

155 and sample cause spherical aberrations that often limit penetration depth and resolution.

156 ic-inorganic heterojunction photovoltaics is often limited by high carrier recombination arising from

157 ucial for the semiconductor industry, but is often limited by the need for lattice matching between t

158 rdability, screening and diagnosis for ID is often limited to proxy hemoglobin measurements alone.

159 Bacteria often live in biofilms, which are microbial communities

160 The CRISPR and the cas locus are often located next to each other in the genomes.

161 aried widely between countries, but was most often low according to WHO indicators (<100 needle-syrin

162 Hit rates are often low, typically around 0.1%, limiting the number of

163 of CO2 in many aquatic systems is variable, often lower than the KM of the primary carboxylating enz

164 -like bodies are seen in the nucleus, and it often manifests as a severe phenotype.

165 he intensity of a parent peak, mimicking and often masking impurity signals.

166 ptation requires changes in gene expression, often mediated by global regulators of transcription.

167 ulation dynamics and species persistence are often mediated by species traits.

168 Postinterventional AKI in these patients is often mild and does not impact renal function at day 30,

169 Despite often minute concentrations in vivo, d-amino acid contai

170 . falciparum infection; however, these tests often miss cases of low-level parasitemia, and PfHRP-II

171 tance to these compounds has begun to emerge often months to years after their initiation.

172 umors, high doses of ionizing radiations are often needed during RT, leading to severe damages to nor

173 Portal annular pancreas is a rare and often neglected pancreatic anomaly due to a lack of awar

174 ic input from their target network, which is often nonreciprocal.

175 ur in the context of official wars, they are often nonviolent, and they are endemic to the region.

176 et of phenomenological parameters, which are often not easily deducible from the underlying atomistic

177 ngs from clinical and biological studies are often not reproducible when tested in independent cohort

178 des an explanation for why Allee effects are often observed in anthropogenically rare species.

179 he heterogeneous fates of metastatic lesions often observed in the clinic post-therapy.

180 rosome determines cell's front, based on its often-observed position in front of the nucleus, has bee

181 Spatial patterning often occurs in ecosystems as a result of a self-organiz

182 ction pathway, other reactive intermediates, often of higher molecular weight than the Amadori rearra

183 e-threatening arrhythmogenic cardiomyopathy, often of right ventricular predominance.

184 e software on simulated data on accuracy and often on speed.

185 large number of PAINS have been classified, often on the basis of individual studies or chemical exp

186 s of attitudes, emotions, and sentiments are often only verbally defined and therefore somewhat vague

187 n a food delivery route, these organisms are often operationally referred to as next-generation probi

188 previous diagnosis of DED by a clinician or "often" or "constant" symptoms of dryness and irritation.

189 ed the presence of diplopia as "sometimes," "often," or "always" in distance straight ahead or readin

190 Within cells, nanostructures are often organized using local assembly rules that produce

191 arget selectivity is not well understood and often overlooked when developing clinically relevant bis

192 However, despite being often overlooked, the infection spread due to contaminat

193 These factors are often overlooked; yet data suggest that the clinical con

194 rozygous for hemoglobin S mutation were less often parasitemic compared to AA adults (odds ratio [OR]

195 In natural systems, biodiversity changes are often part of a bigger community assembly dynamic.

196 Exposure to blood-stage malaria infection is often persistent, leading to generation of CD4 effector

197 However, these procedures often place pressure and volume loads on the heart, and

198 hat commonly consume plants, to estimate how often plant feeding has arisen and to test whether this

199 mbiotic and pathogenic relationships, but is often poorly understood at the molecular level.

200 popular scientific press and blogosphere too often portray the job of a research-intensive faculty me

201 ction difficult, so that food authentication often poses a challenge.

202 Organic molecules with heteroatoms often possess an important excited-state relaxation chan

203 volvement during early thymocyte development often precludes direct analysis of potential roles durin

204 ible via photoluminescence, these states are often probed using photocurrent methods that require eff

205 Aggressive approaches to repeat resolution often produce misassemblies, and conservative approaches

206 The stimulation protocol often produced increases in global network excitability

207 This coloration is often produced through the deposition of diet-derived ca

208 gious lives of many ancestral humans, and is often proposed by anthropologists to be the "first profe

209 Exposure to dog and cat allergens in DCC often reached levels of households with pets.

210 bility-associated activity patterns are most often reactivated separately.

211 l modulatory neurons can be complex, as they often receive input from a variety of sources and are di

212 Although migraine is often recognised in women, it is underdiagnosed in men,

213 noconjunctivitis-specific quality of life is often reduced during seasonal allergies.

214 of chromatographically unresolved compounds, often referred to as humic-like substances (HULIS), whic

215 re dependence of the normal state resistance often referred to as the N-shaped temperature dependence

216 ng, whereas the medial orbitofrontal cortex (often referred to as ventromedial prefrontal cortex in h

217 e use of a distant reference electrode, they often reflect those of synaptic activity occurring in di

218 active bath on the inclusions or boundaries often regulate function, and such forces may also be exp

219 a small number of facial features that were often related to geometrically large parts like face out

220 The presence of polyphenols is often related to the colour of the pulse and to its anti

221 ymatic processes and protein polymerizations often relies on the use of supramolecular interactions a

222 Emotional events are often remembered better than neutral events, a benefit t

223 ver, coexisting structurally similar isomers often render an unambiguous identification impossible.

224 However, poor scaling often renders direct ab initio calculations intractable

225 r, to procure such drugs as cocaine, addicts often require considerable ingenuity and flexibility in

226 been used as protein carriers, however they often require covalent fusion to the protein for efficie

227 ot be seriously ill or injured, but policies often require immediate transport to an emergency depart

228 y and antimicrobial susceptibility, but they often require several days of turnaround time, which lea

229 Thin film oxide materials often require thermal treatment at high temperature duri

230 Swift action is often required in the face of indeterminate sensory evid

231 Contrast material is often required to clearly visualize the functional archi

232 Successful implementation of CRISPR often requires Cas9 to elicit efficient target knockout

233 In contrast, perceptual learning often requires extensive practice within a day for perfo

234 ty of a disease locus is a complex task that often requires supporting data from both statistical gen

235 be used to track implanted cells in vivo but often requires the addition of an exogenous contrast age

236 ponses; genes in an inactive chromatin state often responded late.

237 talytic transformations used by chemists are often restricted to simple functional-group interconvers

238 r transcatheter aortic valve replacement and often result in permanent pacemaker (PPM) implantation.

239 injury (TBI) causes extensive neural damage, often resulting in long-term cognitive impairments.

240 y stochastic fluctuations in actin dynamics, often resulting in traveling waves of protrusion.

241 Analysis of next-generation sequencing data often results in a list of genomic regions.

242 life history of facultative pathogens likely often results in ecological tradeoffs associated with pe

243 We aimed to determine how often S aureus is transmitted from health-care workers o

244 mportant source of forage for bees, which is often scarce in agro-ecosystems.

245 In phylogenetics, we often seek to reconcile gene trees with species trees wi

246 from mild to life-threatening reactions and often seems to depend on the route of exposure.

247 It is often sensory-predominant with pain and can lead to long

248 ealth care reform and surgical education are often separated functionally.

249 CH stretches in hydrocarbon cations often shift to lower frequencies relative to neutral mol

250 Animals often show reduced reproductive success in urban compare

251 ning an accreting black hole or neutron star often show x-ray emission extending to high energies (>1

252 redicted in silico and validated by RT-qPCR, often showed opposite expression profiles than the relat

253 h as doping with fine particles and alloying often significantly decrease their conductivity.

254 Given that this brain region is often spared in aphasic stroke, we propose that it is a

255 Behavioural and emotional problems often start in early childhood, and this might be partic

256 s, nocturnally migrating Swainson's Thrushes often stop on the northern Gulf of Mexico coast before f

257 sfer in condensed-phase molecular systems is often strongly coupled to intramolecular vibrations that

258 Microorganisms are often studied as populations but the behaviour of single

259 ing area in electronics development, but are often stymied by the large minimum feature size.

260 content of pancreatic cyst fluid aspirate is often suboptimal for analysis, but DNA isolated from lys

261 more traditional imaging methods despite its often-superior performance.

262 Within the LGN, neuronal responses are often suppressed by stimuli that extend beyond the class

263 Tree radial growth is often systematically limited by water availability, as i

264 Intrusive memories often take the form of distressing images that emerge in

265 Measures often taken after the first event are ineffective in imp

266 Treatment strategies for these diseases have often targeted downstream pathways to ameliorate consequ

267 mporarily disrupted made biased choices more often than a control group.

268 ombinations of phenotypes that co-occur more often than expected by chance.

269 t both convergence and divergence occur more often than expected.

270 ed in models as a significant predictor more often than relative humidity, solar irradiation, or temp

271 rried parasites, including gametocytes, more often than their AA counterparts (OR 3.01 95% CI 1.38-6.

272 The use of a secondary oven is often the solution to the problem.

273 Most often, the scores regarding staffing and resource adequa

274 However, although empathy is often thought to be automatic, recent theories have argu

275 Moreover, CR+ interneurons are often treated in models as a single homogenous populatio

276 Atherothrombotic vascular disease is often triggered by a distinct type of atherosclerotic le

277 ccupation, symptoms, and travel history were often unavailable to the laboratory and, therefore, less

278 HPAI) viruses, but such viruses' origins are often unclear.

279 e stroke, is frequently intermittent, and is often undetected.

280 g architecture of the local actin network is often unknown.

281 e of mesial temporal lobe epilepsy (MTLE) is often unknown.

282 rom single transcriptomic study, however, is often unstable and not generalizable due to cohort bias,

283 Extubation is often unsuccessful owing to lung disease or inadequate r

284 Ecologists often use image capture to bolster data collection in ti

285 nstead simple dose-response models are still often used although they only exploit data observed at t

286 Yellow fluorescent protein (YFP) is often used as an acceptor but YFP is prone to photobleac

287 the cyanobacterial version phycocyanobilin, often used for optogenetics, has a dramatically stabiliz

288 and descriptions of biofabrication that are often used interchangeably or inconsistently in the curr

289 amounts of missing values, and imputation is often used to create complete data sets for analysis.

290 t radiotherapy (RT) in breast cancer (BC) is often used to eradicate remaining tumor cells following

291 During hydraulic fracturing, a technique often used to extract hydrocarbons from shales, large vo

292 ess rate of generating these costructures is often variable, in particular when working with dynamic

293 The capacity to tolerate climate change often varies across ontogeny in organisms with complex l

294 NP delivery is often via the parenteral route, reliant on administratio

295 he concentrations of these two compounds are often well correlated.

296 presented (the "triple-flash" illusion) most often when the interflash delay matches the period of pa

297 as Ag25(SR)18, Ag29(S2R)12, and Ag44(SR)30 (often with a few counterions to compensate charges) are

298 ry (TBI) is a serious public health problem, often with devastating consequences for patients and the

299 t preparations of alpha-amino boronic acids, often with high stereoselectivity, thereby facilitating

300 Bats serve as a reservoir for various, often zoonotic viruses, including significant human path