ライフサイエンスコーパス: olefin metathesis

1 Finally, the C-ring was closed using olefin metathesis.

2 resulted in a highly efficient catalyst for olefin metathesis.

3 r architectures are produced by ring-closing olefin metathesis.

4 n dimer via ruthenium-catalyzed ring-closing olefin metathesis.

5 cond catalyst (molecular or solid-phase) for olefin metathesis.

6 ivity and selectivity profiles in asymmetric olefin metathesis.

7 ation of the C-3 side-chain and ring-closing olefin metathesis.

8 one based upon olefination and a second upon olefin metathesis.

9 step by a novel ring-expansion method using olefin metathesis.

10 onserves the key features of metal-catalyzed olefin metathesis.

11 ected diene (13), which is then cyclized via olefin metathesis.

12 the precursors of the most active sites for olefin metathesis.

13 reas that have historically been enhanced by olefin metathesis.

14 ries of novel ruthenium complexes for use in olefin metathesis.

15 cobalt(II) cations, followed by ring-closing olefin metathesis.

16 lent capture of the catenane by ring-closing olefin metathesis.

17 complex, widely regarded as inactive toward olefin metathesis.

18 ollowed by selective degradation of PB using olefin metathesis.

19 ed based on macrocyclization by ring-closing olefin metathesis.

20 e E-olefins, a previously unmet challenge in olefin metathesis.

21 somers, which concurrently undergo catalytic olefin metathesis.

22 enerating adaptive cross-linked polymers via olefin metathesis.

23 the appropriate chelate for stereocontrolled olefin metathesis.

24 HC) ligands that catalyze highly Z-selective olefin metathesis.

25 A major shortcoming in olefin metathesis, a chemical process that is central to

26 activated with excess AlCl3 to form cationic olefin metathesis-active W-complexes; however, these rea

27 ore strongly bound sites are responsible for olefin metathesis activity and are formed preferentially

28 We also evaluate the olefin metathesis activity of NHC-coordinated complexes

29 The synthesis, structure, and olefin metathesis activity of the first neutral and cati

30 the overhand knot end groups by ring-closing olefin metathesis affords a single enantiomer of the tre

31 d metabolic stability of these bonds renders olefin metathesis an exceptional methodology for the syn

32 Ag(I) carbene) that promote enantioselective olefin metathesis and allylic alkylations with scope tha

33 Y groups in model reactions of Ru-catalyzed olefin metathesis and Pd-catalyzed C-C cross-coupling.

34 peptide coupling, nucleophilic substitution, olefin metathesis, and click reactions have been the met

35 the coupling of two complex segments via an olefin metathesis, and the subsequent conversion of a di

36 f spirocyclic structures by enantioselective olefin metathesis are also disclosed.

37 Ru-based catalysts for efficient Z-selective olefin metathesis are featured.

38 nces of Z- and enantioselective Ru-catalyzed olefin metathesis are presented.

39 e, we demonstrate transition-metal-catalyzed olefin metathesis as a simple, effective method for heal

40 addition, Suzuki-Miyaura cross-coupling, and olefin metathesis as key steps to assemble various unnat

41 rt-butanesulfinyl aldimine, and ring closing olefin metathesis as key steps.

42 a notable effect on broadening the scope of olefin metathesis, as the stability of methylidene compl

43 hly active catalyst systems, the isomerizing olefin metathesis becomes an efficient way to access def

44 the highly active, fast-initiating ruthenium olefin metathesis catalyst (H(2)IMes)(pyr)(2)(Cl)(2)RuCH

45 The structure of ruthenium-based olefin metathesis catalyst 3 and model pi-complex 5 in s

46 ivate it as a low temperature, heterogeneous olefin metathesis catalyst and confers both high activit

47 as the implications of these dynamics toward olefin metathesis catalyst and reaction design are descr

48 nvolves the use of Grubbs' second-generation olefin metathesis catalyst for cross-metathesis of alkyl

49 The classical WO3/SiO2 olefin metathesis catalyst is combined to other catalyst

50 r agent (CTA) with a highly active ruthenium olefin metathesis catalyst resulted in the formation of

51 benzenethiolate ligand resulted in an active olefin metathesis catalyst with remarkable Z selectivity

52 tive tone photoresist using a photoactivated olefin metathesis catalyst, which can be quickly prepare

53 The thermal stability of selected olefin metathesis catalysts allowed elevated temperature

54 ies for the design and implementation of new olefin metathesis catalysts and substrates are discussed

55 Ruthenium-based olefin metathesis catalysts are used in laboratory-scale

56 A new family of ruthenium-based olefin metathesis catalysts bearing a series of thiazole

57 Ruthenium-based olefin metathesis catalysts bearing dithiolate ligands h

58 A series of ruthenium olefin metathesis catalysts bearing N-heterocyclic carbe

59 Mo and W MonoAryloxide-Pyrrolide (MAP) olefin metathesis catalysts can couple terminal olefins

60 The synthesis of olefin metathesis catalysts containing chiral, monodenta

61 A library of 29 homologous Ru-based olefin metathesis catalysts has been tested for ethenoly

62 Ru- or Mo-based chiral olefin metathesis catalysts have proven to be inefficien

63 Monoaryloxide-pyrrolide (MAP) olefin metathesis catalysts of molybdenum that contain a

64 A series of ruthenium olefin metathesis catalysts of the general structure (H(

65 Olefin metathesis catalysts provide access to molecules

66 erves as a platform for the discovery of new olefin metathesis catalysts that allow for efficient com

67 the first-generation, phosphine-based Grubbs olefin metathesis catalysts to second-generation catalys

68 A series of second-generation ruthenium olefin metathesis catalysts was investigated using a com

69 oach to access a new family of Ru-alkylidene olefin metathesis catalysts with specialized properties

70 They are highly active olefin metathesis catalysts, allowing for turnover numbe

71 ve species of industrial supported MoO3/SiO2 olefin metathesis catalysts.

72 R(3))(Cl)(2)Ru=CHR', which are highly active olefin metathesis catalysts.

73 he mechanism and activity of ruthenium-based olefin metathesis catalysts.

74 nium benzylidene complexes are well-known as olefin metathesis catalysts.

75 st is fully compatible with state-of-the-art olefin metathesis catalysts.

76 scope of catalyst-controlled stereoselective olefin metathesis considerably.

77 n-chain polypseudorotaxanes via ring-opening olefin metathesis copolymerization of macrocycles and me

78 nyl-3-pentene-1,5-diyl)iron complexes toward olefin metathesis, cycloaddition, and mild oxidations (M

79 Recent examples of this approach include olefin-metathesis-derived macrocycles that employ ring c

80 d to prepare variants of previously reported olefin-metathesis-derived macrocycles.

81 cond-generation strategy, a remarkable cross olefin metathesis dimerization cascade was discovered an

82 eometrical isomer by use of silicon-tethered olefin metathesis employing the Schrock carbene [(CF3)2M

83 tional group tolerance of ruthenium-mediated olefin metathesis enables a host of new possibilities fo

84 mework in SALEM-14 prevents "intermolecular" olefin metathesis from occurring between the pillars in

85 , no general protocol for catalytic carbonyl-olefin metathesis has been reported.

86 Olefin metathesis has emerged as a promising strategy fo

87 Lately, stereoretentive olefin metathesis has garnered much attention as a metho

88 Olefin metathesis has had a large impact on modern organ

89 Olefin metathesis has recently emerged as a viable react

90 ctivated ruthenium catalysts for Z-selective olefin metathesis have been synthesized.

91 Recent studies in olefin metathesis have focused on the synthesis of catal

92 carbonylation, polymerization, cyclization, olefin metathesis, Heck coupling, hydroarylation Michael

93 prepared in a one-pot tandem dehydrogenation/olefin metathesis/hydrogenation sequence directly from a

94 The scope and limitations of olefin metathesis in bioconjugation, however, remain unc

95 ptides but also for applying stereoselective olefin metathesis in general synthetic endeavors.

96 oconjugation but also for the application of olefin metathesis in general synthetic endeavors.

97 a mechanochemical approach for Ru-catalyzed olefin metathesis, including cross-metathesis and ring-c

98 Olefin metathesis is a powerful tool for the formation o

99 Olefin metathesis is an incredibly valuable transformati

100 The utility of H-bonding in catalytic olefin metathesis is elucidated through development of e

101 Olefin metathesis is increasingly incorporated in polyfu

102 This ring-expanding olefin metathesis is suggested to be a simple way to pre

103 neration Grubbs catalyst, the ring-expanding olefin metathesis of a monocyclooct-4-en-1-yl functional

104 Olefin metathesis of the triene substrate 12 afforded th

105 A synthesis via olefin metathesis of the unprotected heterocycle and a c

106 n numerous significant advances in catalytic olefin metathesis (OM) during the past two decades.

107 molecules traditionally generated by olefin-olefin metathesis or olefination.

108 A tandem olefin metathesis/oxidative cyclization has been develop

109 le, underwent an entropy-driven ring-opening olefin metathesis polymerization (ROMP) to provide a pol

110 pment of catalyst-controlled stereoselective olefin metathesis processes has been a pivotal recent ad

111 y with which allylic alcohols participate in olefin metathesis processes will be presented as well.

112 atter compounds through Wacker oxidation and olefin metathesis provides diversely functionalized buil

113 shed in the field of chiral Ru- and Mo-based olefin metathesis, providing an asymmetric access to str

114 synthesis exploits the power of ring-closing olefin metathesis (RCM) in a stereospecific way.

115 atic hydrocarbons (PAHs) by the ring-closing olefin metathesis (RCM) of pendant olefins on a phenylen

116 lkenyl amino acids and (ii) the ring-closing olefin metathesis (RCM) of the resulting resin-bound pep

117 es of these macrocycles feature ring-closing olefin metathesis (RCM) reactions catalyzed by ruthenium

118 -1' on the tricyclic core via a ring-closing olefin metathesis (RCM) strategy with the second-generat

119 kylidene 1 and undergone facile ring-closing olefin metathesis (RCM) to give 21- and 23-membered macr

120 CH2)3N]Mo(NB(C6F5)3) with PMe3, ring-closing olefin metathesis (RCM) was employed to join the aryl ri

121 n A analogues were synthesized utilizing the olefin metathesis reaction and evaluated in a calcineuri

122 While the corresponding carbonyl-olefin metathesis reaction can also be used to construct

123 Specifically, the catalytic olefin metathesis reaction has led to profound developme

124 ety of C-1-disaccharide glycals based on the olefin metathesis reaction of enol ethers and alkenes is

125 The olefin metathesis reaction of two unsaturated substrates

126 eased phosphine dissociation leads to faster olefin metathesis reaction rates, which is of direct sig

127 ct relative stereochemistry and (2) a double olefin metathesis reaction to deliver both cyclohexene r

128 e synthetic approach was the diene-ene cross olefin metathesis reaction to generate the C6-C7 olefin

129 lecular wire can be grown in situ through an olefin metathesis reaction.

130 nd C (3) was constructed using an impressive olefin metathesis reaction.

131 s accomplished efficiently by a ring-closing olefin metathesis reaction.

132 here is no single mechanism for the Ru-based olefin metathesis reaction.

133 significant catalytic activity in promoting olefin metathesis reactions and provide products of high

134 onic units on the efficiency of Ru-catalyzed olefin metathesis reactions are discussed.

135 derivatives, promote exceptional Z-selective olefin metathesis reactions are elucidated.

136 s that control the stereochemical outcome of olefin metathesis reactions have been recently introduce

137 for turnover numbers up to 10,000 in various olefin metathesis reactions including alkenes bearing ni

138 nalized Ru nanoparticles were synthesized by olefin metathesis reactions of carbene-stabilized Ru nan

139 eported herein efficiently promote benchmark olefin metathesis reactions such as the ring-closing of

140 and are able to participate in high-yielding olefin metathesis reactions that afford acyclic 1,2-disu

141 d initiation as well as overall activity for olefin metathesis reactions was examined.

142 Olefin metathesis reactions with 3E-1,3-dienes using Z-s

143 e resulting nanoparticles could also undergo olefin metathesis reactions with vinyl-terminated molecu

144 gn principle of iron(III)-catalyzed carbonyl-olefin metathesis reactions.

145 ls of stereochemical control in Ru-catalyzed olefin metathesis reactions.

146 The success of enantioselective olefin metathesis relies on the design of enantioenriche

147 ort the development of a facile ring-opening olefin metathesis route to alkaline anion exchange membr

148 for catalytic and thermally allowed carbonyl-olefin metathesis (see scheme).

149 The development of a catalytic carbonyl-olefin metathesis strategy is reported, in the context o

150 ides were found to be exceptionally reactive olefin metathesis substrates, enabling a broad range of

151 A novel one pot olefin metathesis-Takai olefination protocol that should

152 lded structurally well-defined catalysts for olefin metathesis that are used to synthesize an array o

153 xchange and postsynthesis modification using olefin metathesis, the noninterpenetrated SALEM-14 was f

154 Catalytic olefin metathesis--through which pairs of C = C bonds ar

155 kbone using ruthenium-catalyzed ring-closing olefin metathesis to afford a molecular charm bracelet s

156 n quaternary stereocenter and a ring-closing olefin metathesis to concomitantly form the spirocyclic

157 The other key steps involved ring-closing olefin metathesis to construct both dihydropyran units,

158 es (1) a remarkably E-selective ring-closing olefin metathesis to construct the 12-membered benzolact

159 ing monomers, followed by ruthenium-mediated olefin metathesis to effect closure of the seven-membere

160 gand strands can be cyclized by ring-closing olefin metathesis to form a molecular trefoil knot in 58

161 lexes is covalently captured by ring-closing olefin metathesis to form topologically chiral molecular

162 only for expanding the scope of Z-selective olefin metathesis to peptides but also for applying ster

163 These olefin metathesis transformations proceed efficiently an

164 oselective epoxide opening, and ring-closing olefin metathesis using Grubbs' catalyst as the key step

165 , was synthesized from a diene precursor via olefin metathesis using Grubbs's catalyst.

166 Advancements in stereoretentive olefin metathesis using tungsten, ruthenium, and molybde

167 and through applications in stereoselective olefin metathesis where Z-alkene substrates are required

168 eta-H elimination) occurs on Ti, followed by olefin metathesis, which occurs on W.

169 or new developments in the field of carbonyl-olefin metathesis, which traditionally relied on stoichi

170 Nonetheless, the full potential of olefin metathesis will be realized only when additional

171 he mechanism and origins of Z-selectivity in olefin metathesis with chelated Ru catalysts were explor

172 -(benzyloxy)-3-buten-2-ol and a ring-closing olefin metathesis with Grubbs' catalyst.

173 nsive computational study of stereoretentive olefin metathesis with Ru-dithiolate catalysts has been

174 However, while the mechanism of olefin metathesis with ruthenium benzylidenes has been w