ライフサイエンスコーパス: oligodendrocyte precursor cell

1 ls in the postnatal SVZ but are likely to be oligodendrocyte precursor cells.

2 proliferation and inhibits the migration of oligodendrocyte precursor cells.

3 eptor thus serves as a phenotypic marker for oligodendrocyte precursor cells.

4 e they likely exert their influence on early oligodendrocyte precursor cells.

5 Similar results were obtained with oligodendrocyte precursor cells.

6 y neurons as well as in oligodendrocytes and oligodendrocyte precursor cells.

7 ransformation following differentiation into oligodendrocyte precursor cells.

8 1 was significantly decreased in spinal cord oligodendrocyte precursor cells after onset of EAE, and

9 s system remyelination is mainly mediated by oligodendrocyte precursor cells, although subventricular

10 reduced remyelination, and increased loss of oligodendrocyte precursor cells and mature oligodendrocy

11 ances in our understanding of the biology of oligodendrocyte precursor cells and of the stage-depende

12 mbination with MCSF, increased the number of oligodendrocyte precursor cells and promoted remyelinati

13 In vitro and in vivo experiments in oligodendrocyte precursor cells and zebrafish were perfo

14 matter, apoptosis and arrested maturation of oligodendrocyte precursor cells, and hypomyelination.

15 ally infected neural stem cells, astrocytes, oligodendrocyte precursor cells, and microglia, whereas

16 ol cells, including normal human astrocytes, oligodendrocyte precursor cells, and primary explant cul

17 resses inflammation, attenuates apoptosis of oligodendrocyte precursor cells, and promotes myelinatio

18 NG2 cells in the SVZ and RMS expressed the oligodendrocyte precursor cell antigen platelet-derived

19 Unlike oligodendrocyte precursor cells, APCs do not differentia

20 ation vulnerable to PVWMI and P5 when rodent oligodendrocyte precursor cells are more vulnerable to e

21 Oligodendrocyte precursor cells are the primary source o

22 her obvious impairment in the recruitment of oligodendrocyte precursor cells, astrocytes, or reactive

23 domains VI and V of netrin-1 repel migrating oligodendrocyte precursor cells, but lack the chemoattra

24 We show that TNFR2 drives differentiation of oligodendrocyte precursor cells, but not proliferation o

25 termine a window of opportunity during which oligodendrocyte precursor cells can successfully differe

26 nes, chemokines and growth factors, act upon oligodendrocyte precursor cells, causing their activatio

27 pression of the helix-loop-helix gene Id4 in oligodendrocyte precursor cells decreases in vivo and in

28 hin the nervous system, including defects in oligodendrocyte precursor cell development and a partial

29 Oligodendrocyte precursor cells differentiate into matur

30 -gamma is a positive regulator of endogenous oligodendrocyte precursor cell differentiation and remye

31 y, we identified novel molecules involved in oligodendrocyte precursor cell differentiation and valid

32 Specifically, exogenous CCL19 abolished oligodendrocyte precursor cell differentiation observed

33 We also show that oligodendrocyte precursor cells display sensitivity to t

34 -1, a secreted protein that repels migrating oligodendrocyte precursor cells during neural developmen

35 In mice that lacked RXR-gamma, adult oligodendrocyte precursor cells efficiently repopulated

36 Motor neuron and oligodendrocyte precursor cells express Olig genes, whic

37 an enrichment of proliferative pathways and oligodendrocyte precursor cell gene expression profile i

38 The alpha1B-AR is also expressed in NG2 oligodendrocyte precursor cells in both neonatal cell cu

39 ) and retinoic acid (RA) induce purified rat oligodendrocyte precursor cells in culture to stop divis

40 nterestingly, despite a normal production of oligodendrocyte precursor cells in the double mutants, o

41 ast to multiple observations indicating that oligodendrocyte precursor cells in the embryonic day 14

42 ne fumarate can stimulate differentiation of oligodendrocyte precursor cells in vitro, in animal mode

43 usly differentiating OLs generated from pure oligodendrocyte precursor cells in vitro.

44 During development, oligodendrocyte precursor cells integrate environmental

45 this compound induces the differentiation of oligodendrocyte precursor cells into mature oligodendroc

46 factors that inhibit the differentiation of oligodendrocyte precursor cells into myelinating oligode

47 Moreover, proliferation of oligodendrocyte precursor cells is altered by mutant hun

48 An intracellular timer in oligodendrocyte precursor cells is thought to help contr

49 udies demonstrated that the proliferation of oligodendrocyte precursor cells isolated from the develo

50 regulated expression of GPR17 in Oli-neu, an oligodendrocyte precursor cell line, making these cells

51 We have identified an oligodendrocyte precursor cell line, termed G144, that s

52 Oligodendrocyte precursor cells may differentiate into a

53 In contrast to oligodendrocyte precursor cells, microglia formed only w

54 velopment, may also be active in controlling oligodendrocyte precursor cell migration in MS, and henc

55 ple sclerosis lesions are thought to inhibit oligodendrocyte precursor cell migration, limiting their

56 entative populations of neurons, astrocytes, oligodendrocyte precursor cells, newly formed oligodendr

57 NG2-expressing oligodendrocyte precursor cells (NG2 cells) are exposed

58 Synaptic signaling to NG2-expressing oligodendrocyte precursor cells (NG2 cells) could be key

59 adult CNS contains an abundant population of oligodendrocyte precursor cells (NG2(+) cells) that gene

60 bipotential oligodendrocyte-type-2 astrocyte/oligodendrocyte precursor cells (O-2A/OPCs).

61 Seeding of oligodendrocyte precursor cells on these axons results i

62 The oligodendrocyte precursor cell (OPC) arises from the sub

63 the proliferation and differentiation of the oligodendrocyte precursor cell (OPC) as well as the spat

64 Temple and Raff previously showed that an oligodendrocyte precursor cell (OPC) can divide a maximu

65 ceptor induced excitotoxicity contributes to oligodendrocyte precursor cell (OPC) damage and hypomyel

66 functional states of Wnt activity determine oligodendrocyte precursor cell (OPC) differentiation and

67 or GABAergic interneuron production, repress oligodendrocyte precursor cell (OPC) formation by acting

68 ons contain hyaluronan deposits that inhibit oligodendrocyte precursor cell (OPC) maturation.

69 ein (BMP) signaling, such as Noggin, promote oligodendrocyte precursor cell (OPC) production after hy

70 Gpr56-knockout mice manifest with decreased oligodendrocyte precursor cell (OPC) proliferation and d

71 ansmembrane proteoglycan NG2 is expressed by oligodendrocyte precursor cells (OPC), which migrate to

72 in reminiscent of neural stem cells (NSC) or oligodendrocyte precursor cells (OPC).

73 type 1 to type 2 status, elevated numbers of oligodendrocyte precursor cells (OPCs) and oligodendrocy

74 yelin is dependent on the differentiation of oligodendrocyte precursor cells (OPCs) and oligodendrocy

75 Oligodendrocyte precursor cells (OPCs) are generated fro

76 Oligodendrocyte precursor cells (OPCs) are lineage-restr

77 Other studies showed that oligodendrocyte precursor cells (OPCs) are responsible f

78 ventral spinal cord, motor neurons (MNs) and oligodendrocyte precursor cells (OPCs) are sequentially

79 Oligodendrocyte precursor cells (OPCs) are the major sou

80 Oligodendrocyte precursor cells (OPCs) are thought to ma

81 We and others have shown that oligodendrocyte precursor cells (OPCs) can also be the c

82 , it was demonstrated that lineage-committed oligodendrocyte precursor cells (OPCs) can be converted

83 Oligodendrocyte precursor cells (OPCs) can be differenti

84 We showed previously that purified rat oligodendrocyte precursor cells (OPCs) can be induced by

85 We previously showed that oligodendrocyte precursor cells (OPCs) can be transforme

86 hereas induced expression of Nkx2.2 in early oligodendrocyte precursor cells (OPCs) causes precocious

87 The appearance of oligodendrocyte precursor cells (OPCs) correlates with t

88 and transplantation of adult rat spinal cord oligodendrocyte precursor cells (OPCs) could enhance rem

89 Remyelination may fail because oligodendrocyte precursor cells (OPCs) do not completely

90 ll-intrinsic timer helps control when rodent oligodendrocyte precursor cells (OPCs) exit the cell cyc

91 In the mammalian CNS, oligodendrocyte precursor cells (OPCs) express most neur

92 Oligodendrocyte precursor cells (OPCs) express NMDA rece

93 Oligodendrocyte precursor cells (OPCs) express receptors

94 ansplantation of neural stem cells (NSCs) or oligodendrocyte precursor cells (OPCs) has been used to

95 Oligodendrocyte precursor cells (OPCs) have extraordinar

96 t hypoxia activates the ISR in primary mouse oligodendrocyte precursor cells (OPCs) in vitro and that

97 lly identified as a proliferative signal for oligodendrocyte precursor cells (OPCs) in vitro.

98 Jagged signalling via Notch receptors on oligodendrocyte precursor cells (OPCs) inhibits their di

99 Transplantation of oligodendrocyte precursor cells (OPCs) is a promising po

100 Adult oligodendrocyte precursor cells (OPCs) make up around 5-

101 rocytes are initially specified, after which oligodendrocyte precursor cells (OPCs) migrate and proli

102 cultured and exposed to media conditioned by oligodendrocyte precursor cells (OPCs) or differentiated

103 Oligodendrocyte precursor cells (OPCs) persist in substa

104 They differentiate from oligodendrocyte precursor cells (OPCs) that are produced

105 the central nervous system and develop from oligodendrocyte precursor cells (OPCs) that must first m

106 f which represent a continuum from Pdgfra(+) oligodendrocyte precursor cells (OPCs) to distinct matur

107 Sox8 is known to be expressed in oligodendrocyte precursor cells (OPCs) together with oth

108 e absence of Gsx2 expression, an increase in oligodendrocyte precursor cells (OPCs) with a concomitan

109 Oligodendrocyte precursor cells (OPCs), a major glial ce

110 yeloid cells, meningeal cells, proliferating oligodendrocyte precursor cells (OPCs), and a dense extr

111 aberrant growth prior to malignancy only in oligodendrocyte precursor cells (OPCs), but not in any o

112 ive AMPARs by recording from rat optic nerve oligodendrocyte precursor cells (OPCs), known to express

113 They develop from oligodendrocyte precursor cells (OPCs), most of which di

114 us examined the functional roles of CSPGs on oligodendrocyte precursor cells (OPCs), oligodendrocytes

115 xclusively expressed in oligodendrocytes and oligodendrocyte precursor cells (OPCs), which migrate co

116 ation program in existing or newly recruited oligodendrocyte precursor cells (OPCs).

117 ta receptors may mediate the effect of TH on oligodendrocyte precursor cells (OPCs).

118 lso expressed by some glial cells, including oligodendrocyte precursor cells (OPCs).

119 re postmitotic and derive from proliferative oligodendrocyte precursor cells (OPCs).

120 of functionally mature oligodendrocytes from oligodendrocyte precursor cells (OPCs).

121 factor-2, a guidance factor for migration of oligodendrocyte precursor cells (OPCs).

122 nhibited the differentiation of purified rat oligodendrocyte precursor cells (OPCs).

123 wild-type controls, as was proliferation of oligodendrocyte precursor cells (OPCs).

124 -length LINGO-1 inhibited differentiation of oligodendrocyte precursor cells (OPCs).

125 ression and function of REST in neonatal rat oligodendrocyte precursor cells (OPCs).

126 e a novel role in white matter by modulating oligodendrocyte precursor cells (OPCs).

127 demyelination, as were numbers of CXCR4+NG2+ oligodendrocyte precursor cells (OPCs).

128 upport the survival and proliferation of rat oligodendrocyte precursor cells (OPCs).

129 al differentiation-promoting effect of TH on oligodendrocyte precursor cells (OPCs): unlike wild-type

130 Oligodendrocyte precursor cells (OPCs; PDGFRalpha+) prod

131 ues extends this active role by showing that oligodendrocyte precursors cells (OPCs) in the hippocamp

132 Human oligodendrocytes precursor cells (OPCs) were stimulated

133 NG2 cells, also known as oligodendrocyte precursor cells or polydendrocytes, whic

134 the proliferation of Sox2 stem cells and NG2 oligodendrocyte precursors cells originating in the SVZ

135 xons or do intrinsic properties of different oligodendrocyte precursor cell populations affect length

136 r glial fibrillary acidic protein (GFAP) and oligodendrocyte precursor cells positive for NG2 proteog

137 ral spinal OLIG2-expressing progenitors, pre-oligodendrocyte precursor cells (pre-OPCs) and OPCs from

138 Here we show that most oligodendrocyte precursor cells purified from postnatal

139 tate-methyltransferase (Gamt) did not affect oligodendrocyte precursor cell recruitment, but resulted

140 G2(+) glia, also known as polydendrocytes or oligodendrocyte precursor cells, represent a new entity

141 c MS lesions and that Notch1 is activated in oligodendrocyte precursor cells (see the related article

142 nt mode of inheritance, in vitro analysis in oligodendrocyte precursor cells showed that mutant prote

143 art of the normal timer that determines when oligodendrocyte precursor cells stop dividing and differ

144 This conditioned media also enhanced oligodendrocyte precursor cell survival, maturation and

145 ived mediators influenced differentiation of oligodendrocyte precursor cells through a crosstalk with

146 signaling contributes to the decision of an oligodendrocyte precursor cell to differentiate-both dur

147 glia/macrophage to lesions nor a failure for oligodendrocyte precursor cells to differentiate and rem

148 itical in regulating the transition of adult oligodendrocyte precursor cells to mature OLs that is es

149 hat certain extracellular signals can induce oligodendrocyte precursor cells to revert to multipotent

150 possible reason is the lack of migration of oligodendrocyte precursor cells to the lesion.

151 efault of the resident stem/precursor cells (oligodendrocyte precursor cells) to differentiate into m

152 NLGN3 is cleaved from both neurons and oligodendrocyte precursor cells via the ADAM10 sheddase.

153 Migration and density of oligodendrocyte precursor cells were normal; however, a

154 erating the correct numbers of WM but not GM oligodendrocyte precursor cells, whereas during astrocyt

155 ntracellular timer that helps determine when oligodendrocyte precursor cells withdraw from the cell c