ライフサイエンスコーパス: oligodendrocyte progenitor cell

1 ves differentiation of oligodendrocytes from oligodendrocyte progenitor cells.

2 otential for recovery mediated by endogenous oligodendrocyte progenitor cells.

3 O mice revealed a specific deficit of NG2(+) oligodendrocyte progenitor cells.

4 s have dramatically increased numbers of CNS oligodendrocyte progenitor cells.

5 mmunocytochemically for oligodendrocytes and oligodendrocyte progenitor cells.

6 white matter is synthesized by proliferating oligodendrocyte progenitor cells.

7 ransplantation or manipulation of endogenous oligodendrocyte progenitor cells.

8 hondroitin sulfate proteoglycan expressed by oligodendrocyte progenitor cells.

9 mote production of new oligodendrocytes from oligodendrocyte progenitor cells.

10 tors of proliferation and differentiation of oligodendrocyte progenitor cells.

11 tire CNS after they have differentiated from oligodendrocyte progenitor cells.

12 ouse for voltage-operated Ca(2+) channels in oligodendrocyte progenitor cells.

13 mouse pluripotent epiblast stem-cell-derived oligodendrocyte progenitor cells.

14 ndent on the survival and differentiation of oligodendrocyte progenitor cells.

15 require technologies to generate functional oligodendrocyte progenitor cells.

16 lates cell cycle exit and differentiation in oligodendrocyte progenitor cells.

17 of betaT4-positive cells with A2B5-positive oligodendrocyte progenitor cells after transplantation (

18 peroxia showed a reduced capacity to protect oligodendrocyte progenitor cells against the toxic effec

19 e of the TUJ-1-positive cells, A2B5-positive oligodendrocyte progenitor cells and A2B5-negative cells

20 by an expression pattern resembling that of oligodendrocyte progenitor cells and carries a distincti

21 and in our studies, primary cultures of both oligodendrocyte progenitor cells and differentiating oli

22 Both parenchymal oligodendrocyte progenitor cells and endogenous adult ne

23 he cellular factors involved in apoptosis of oligodendrocyte progenitor cells and oligodendrocytes, a

24 r for cell proliferation), NG2 (a marker for oligodendrocyte progenitor cells) and brain-derived neur

25 In the developing spinal cord, early oligodendrocyte progenitor cells are induced from the ve

26 Oligodendrocyte progenitor cells are stem cells in the c

27 ation that human embryonic stem cell-derived oligodendrocyte progenitor cells are susceptible to JC v

28 nical translation: first, transplantation of oligodendrocyte progenitor cells as a means of treating

29 vides direct evidence that targeting EGFR in oligodendrocyte progenitor cells at a specific time afte

30 However, myosin-1d was undetectable in oligodendrocyte progenitor cells at early and late time

31 alphavveta3 integrin may play in regulating oligodendrocyte progenitor cell behaviour, cells of the

32 pression of syntaxin 4 but not syntaxin 3 in oligodendrocyte progenitor cells but not immature oligod

33 PIKE-L expression is up-regulated when oligodendrocyte progenitor cells commit to differentiati

34 Both oligodendrocyte progenitor cell commitment and oligodend

35 strates a unique role for Olig1 in promoting oligodendrocyte progenitor cell commitment, differentiat

36 mportant roles for Sox17 in controlling both oligodendrocyte progenitor cell cycle exit and different

37 and constitutive ablation of NR1 in neonatal oligodendrocyte progenitor cells did not interrupt their

38 ous system (CNS) most often is the result of oligodendrocyte progenitor cells differentiating into my

39 elevant, FDA-approved compounds that promote oligodendrocyte progenitor cell differentiation and indu

40 endrocyte lineage cells completely inhibited oligodendrocyte progenitor cell differentiation and myel

41 Treg directly promoted oligodendrocyte progenitor cell differentiation and myel

42 tory supernatants also resulted in decreased oligodendrocyte progenitor cell differentiation without

43 se activity is upregulated very early during oligodendrocyte progenitor cell differentiation.

44 myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation.

45 d neither a direct nor an indirect impact on oligodendrocyte progenitor cell differentiation.

46 enhancer (PIKE) expression by shRNA prevents oligodendrocyte progenitor cell differentiation.

47 ess and promotes precocious neurogenesis and oligodendrocyte progenitor cell elaboration.

48 We have previously shown that oligodendrocyte progenitor cells exhibit developmental s

49 TACE deficiency in oligodendrocyte progenitor cells following demyelination

50 brinogen inhibits nerve repair by preventing oligodendrocyte progenitor cells from differentiating in

51 Studies with oligodendrocyte progenitor cells from INK4a-/- mice indi

52 In purified cerebellar oligodendrocyte progenitor cells, glutamate receptor ago

53 arative capabilities, and transplantation of oligodendrocyte progenitor cells, have generated substan

54 Oligodendrocyte progenitor cells identified by mAb A2B5

55 cal studies revealed that the recruitment of oligodendrocyte progenitor cells in response to demyelin

56 us studies have suggested the persistence of oligodendrocyte progenitor cells in the adult mammalian

57 e fifth major cell population that serves as oligodendrocyte progenitor cells in the postnatal CNS.

58 eration of human oligodendrocytes from human oligodendrocyte progenitor cells in vitro.

59 Apoptosis of oligodendrocyte progenitor cells induced by growth facto

60 ly tune axonal diameter, promote re-entry of oligodendrocyte progenitor cells into the cell cycle, or

61 netic nanoparticles, and transplanted tagged oligodendrocyte progenitor cells into the spinal cord of

62 se embryonic and lung fibroblasts to induced oligodendrocyte progenitor cells (iOPCs) using sets of e

63 a novel mechanism by which proliferation of oligodendrocyte progenitor cells is regulated in the pos

64 process formation were also inhibited in the oligodendrocyte progenitor cell line CG-4 after suppress

65 of transplanted cells co-labeled for NG2, an oligodendrocyte progenitor cell marker, but not for neur

66 urons and astrocytes remains the same, early oligodendrocyte progenitor cell markers are decreased in

67 As shown recently, failure in oligodendrocyte progenitor cell maturation contributes t

68 of an early oligodendrocytic promoter, these oligodendrocyte progenitor cells may be extracted and pu

69 on rather than uncontrolled proliferation of oligodendrocyte progenitor cells may have important impl

70 Endogenous oligodendrocyte progenitor cells may represent a viable

71 aling in establishing a motile phenotype for oligodendrocyte progenitor cell migration in vivo and il

72 immature oligodendrocyte-lineage cells, with oligodendrocyte progenitor cells more vulnerable to inju

73 Oligodendrocyte progenitor cell number decreased with ag

74 Many physiologically important activities of oligodendrocyte progenitor cells (O-2A cells), including

75 g development of the central nervous system, oligodendrocyte progenitor cells (O-2A) undergo an order

76 al and mesenchymal glioblastoma, relative to oligodendrocyte progenitor cells (Oli-Neu).

77 ed to the expansion of genetically wild-type oligodendrocyte progenitor cells, oligodendrocyte differ

78 Nonproliferating oligodendrocyte progenitor cells, oligodendrocytes, and

79 compression on the function and survival of oligodendrocyte progenitor cells/oligodendrocytes and ax

80 e found that AXIN2 was expressed in immature oligodendrocyte progenitor cells (OLPs) in white matter

81 ze the effects of BCNU on clonal cultures of oligodendrocyte progenitor cells-one of the best-charact

82 Recently, we showed oligodendrocyte progenitor cell (OPC) accumulation and r

83 In oligodendrocyte progenitor cell (OPC) cultures, IL-11 re

84 d Ca(2+) channels (L-VOCCs) are required for oligodendrocyte progenitor cell (OPC) development, we ge

85 n by acting at several critical steps during oligodendrocyte progenitor cell (OPC) development.

86 The effect of olesoxime on oligodendrocyte progenitor cell (OPC) differentiation an

87 d increases both adult mouse and adult human oligodendrocyte progenitor cell (OPC) differentiation, i

88 he ventral telencephalon were generated, but oligodendrocyte progenitor cell (OPC) generation was sev

89 se (MAPK)-dependent pathway is implicated in oligodendrocyte progenitor cell (OPC) lineage progressio

90 re infants results in inflammation, arrested oligodendrocyte progenitor cell (OPC) maturation, and re

91 ibute to remyelination failure by perturbing oligodendrocyte progenitor cell (OPC) maturation.

92 This work describes the role of oligodendrocyte progenitor cell (OPC) microRNAs (miRNAs)

93 two nf1 orthologs in zebrafish and show that oligodendrocyte progenitor cell (OPC) numbers are increa

94 Oligodendrocyte death and oligodendrocyte progenitor cell (OPC) proliferation duri

95 We have previously demonstrated that oligodendrocyte progenitor cell (OPC) proliferation is c

96 Human oligodendrocyte progenitor cell (OPC) specification and

97 erived growth factor receptor alpha-positive oligodendrocyte progenitor cells (OPC) located within th

98 alpha)-expressing stromal cells derived from oligodendrocytes progenitor cells (OPC) were discovered

99 ntiate human embryonic stem cells (hESCs) to oligodendrocyte progenitor cells (OPCs) according to dev

100 se genes was measured in primary neurons and oligodendrocyte progenitor cells (OPCs) after inflammato

101 Microarray analysis in oligodendrocyte progenitor cells (OPCs) after Sox17 atte

102 AMPA stimulation of cultured oligodendrocyte progenitor cells (OPCs) also caused an i

103 in vitro primary rat embryonic cell model of oligodendrocyte progenitor cells (OPCs) and a mouse N20.

104 ation at the same site, eventually depleting oligodendrocyte progenitor cells (OPCs) and exhausting t

105 hogenetic protein (BMP) signaling pathway in oligodendrocyte progenitor cells (OPCs) and suppresses r

106 expression in the developing CNS identifies oligodendrocyte progenitor cells (OPCs) and whose activa

107 , both the proliferation and total number of oligodendrocyte progenitor cells (OPCs) appeared normal

108 ination and why remyelination is absent when oligodendrocyte progenitor cells (OPCs) are present.

109 In the postnatal brain, oligodendrocyte progenitor cells (OPCs) arise from the s

110 termination of proliferation determines when oligodendrocyte progenitor cells (OPCs) can initiate dif

111 Oligodendrocyte progenitor cells (OPCs) can repair demye

112 Remyelination by oligodendrocyte progenitor cells (OPCs) can restore thes

113 ular mechanisms that drive the maturation of oligodendrocyte progenitor cells (OPCs) during the remye

114 l myelinating glial cells, centrally derived oligodendrocyte progenitor cells (OPCs) ectopically exit

115 Here, we report that oligodendrocyte progenitor cells (OPCs) express function

116 fish, we observed that prior to myelination, oligodendrocyte progenitor cells (OPCs) extend processes

117 factor-1 (IGF-1) provides neuroprotection to oligodendrocyte progenitor cells (OPCs) following cerebr

118 y also be a radial component of migration of oligodendrocyte progenitor cells (OPCs) from a ventral s

119 Migration of oligodendrocyte progenitor cells (OPCs) from proliferati

120 mice also exhibited an increased density of oligodendrocyte progenitor cells (OPCs) in CNS white mat

121 Oligodendrocyte progenitor cells (OPCs) in demyelinated

122 e show that the expression of Sox2 occurs in oligodendrocyte progenitor cells (OPCs) in rodent models

123 fficulties in generating pure populations of oligodendrocyte progenitor cells (OPCs) in sufficient qu

124 ion, and may contribute to the production of oligodendrocyte progenitor cells (OPCs) in the dorsal co

125 Oligodendrocyte progenitor cells (OPCs) in the postnatal

126 of human embryonic stem cell (hESC)-derived oligodendrocyte progenitor cells (OPCs) into adult rat s

127 Differentiation of oligodendrocyte progenitor cells (OPCs) into mature olig

128 n obligatory step for the differentiation of oligodendrocyte progenitor cells (OPCs) into myelinating

129 in disorders can be treated by transplanting oligodendrocyte progenitor cells (OPCs) into the affecte

130 Differentiation and maturation of oligodendrocyte progenitor cells (OPCs) involve the asse

131 cal changes, while in developing neurons and oligodendrocyte progenitor cells (OPCs) it induces cellu

132 lutamatergic synapses onto adult-born NG2(+) oligodendrocyte progenitor cells (OPCs) migrating from t

133 t oligodendrocytes, whether by transplanting oligodendrocyte progenitor cells (OPCs) or by mobilizing

134 n which Tsc1 is deleted by Cre expression in oligodendrocyte progenitor cells (OPCs) or in premyelina

135 Neonatal engraftment by oligodendrocyte progenitor cells (OPCs) permits the myel

136 Oligodendrocyte progenitor cells (OPCs) persist in human

137 We show how Sox2 is expressed in oligodendrocyte progenitor cells (OPCs) preparing to und

138 In experimental models, oligodendrocyte progenitor cells (OPCs) rather than prev

139 Oligodendrocyte progenitor cells (OPCs) recruited to dem

140 Oligodendrocyte progenitor cells (OPCs) that are positiv

141 isoprenoid and cholesterol synthesis, causes oligodendrocyte progenitor cells (OPCs) to migrate past

142 er, direct injection of neural stem cells or oligodendrocyte progenitor cells (OPCs) to the lesion si

143 in which we targeted Notch1 inactivation to oligodendrocyte progenitor cells (OPCs) using Olig1Cre a

144 ation by blocking the differentiation of rat oligodendrocyte progenitor cells (OPCs) via modulation o

145 Many chronically demyelinated lesions have oligodendrocyte progenitor cells (OPCs) within their bor

146 mong three macroglial progenitor populations-oligodendrocyte progenitor cells (OPCs), astrocytes and

147 In oligodendrocyte progenitor cells (OPCs), Lrp1 is require

148 In cultured oligodendrocyte progenitor cells (OPCs), Sox17 levels we

149 tly characterized by scarce undifferentiated oligodendrocyte progenitor cells (OPCs), suggesting the

150 gene expression profiling on purified murine oligodendrocyte progenitor cells (OPCs), the remyelinati

151 rve conduction, and the ectopic migration of oligodendrocyte progenitor cells (OPCs), the resident my

152 rotein fibronectin perturb the maturation of oligodendrocyte progenitor cells (OPCs), thereby impedin

153 Since one role of NG2 glia is that of oligodendrocyte progenitor cells (OPCs), we investigated

154 cells produces first motor neurons and then oligodendrocyte progenitor cells (OPCs), which migrate,

155 and generate de novo synapses with recruited oligodendrocyte progenitor cells (OPCs), which, early af

156 liferation, migration and differentiation of oligodendrocyte progenitor cells (OPCs).

157 modulator of intracellular Ca(2+) levels in oligodendrocyte progenitor cells (OPCs).

158 lay a fundamental role in the development of oligodendrocyte progenitor cells (OPCs).

159 glial-restricted progenitors cells, known as oligodendrocyte progenitor cells (OPCs).

160 ig1-Cre-expressing cells reduces the pool of oligodendrocyte progenitor cells (OPCs).

161 cytes arise from migratory and proliferative oligodendrocyte progenitor cells (OPCs).

162 ult human forebrain contain large numbers of oligodendrocyte progenitor cells (OPCs).

163 h activity could promote formation of excess oligodendrocyte progenitor cells (OPCs).

164 emyelination by impairing differentiation of oligodendrocyte progenitor cells (OPCs).

165 endent on recruitment and differentiation of oligodendrocyte progenitor cells (OPCs).

166 myelin and myelin repair by differentiating oligodendrocyte progenitor cells (OPCs).

167 most PLP-EGFP-expressing cells gave rise to oligodendrocyte progenitor cells (OPCs).

168 iated neuroinflammation, and an expansion of oligodendrocyte progenitor cells (OPCs).

169 the generation of new oligodendrocytes from oligodendrocyte progenitor cells (OPCs).

170 nated is crucial to our understanding of how oligodendrocyte progenitor cells (OPs) develop into myel

171 Proliferative oligodendrocyte progenitor cells (OPs) express large, de

172 Genetic deletion of TACE in oligodendrocyte progenitor cells (OPs) induces premature

173 els to selectively delete TACE expression in oligodendrocyte progenitors cells (OPs), we found that T

174 Parenchymal oligodendrocyte progenitor cells (pOPCs) are considered

175 migration, survival, and differentiation of oligodendrocyte progenitor cells, precursors to myelin-f

176 In the absence of ERK1/ERK2 signaling NG2(+) oligodendrocyte progenitor cells proliferated and differ

177 infiltrates and demyelination, and increased oligodendrocyte progenitor cell proliferation and BDNF+

178 Oligodendrocyte progenitor cell proliferation was observ

179 el blocker tetraethylammonium also inhibited oligodendrocyte progenitor cell proliferation.

180 uced myelin were examined for remyelination, oligodendrocyte progenitor cells, reactive astrocytes, a

181 On the other hand, it is possible that oligodendrocyte progenitor cells remain undifferentiated

182 Differentiation of oligodendrocyte progenitor cells requires activation of

183 enriched population of cells expressing the oligodendrocyte progenitor cell-specific marker NG2.

184 noted because Nkx2.2 promotes maturation of oligodendrocyte progenitor cells specified by expression

185 sis, remyelination can fail despite abundant oligodendrocyte progenitor cells, suggesting impairment

186 d with a truncated proliferative response of oligodendrocyte progenitor cells, suggesting that deplet

187 /or indirectly (via astrocytes) impact human oligodendrocyte progenitor cell survival and differentia

188 to eightfold greater number of proliferating oligodendrocyte progenitor cells than did wild-type (wt)

189 w that miconazole and clobetasol function in oligodendrocyte progenitor cells through mitogen-activat

190 ibility of human embryonic stem cell-derived oligodendrocyte progenitor cells to infection with JC vi

191 y changes during the transition from A2B5(+) oligodendrocyte progenitor cells to premyelinating GalC(

192 man adult brain-derived oligodendrocytes and oligodendrocyte progenitor cells under conditions of met

193 Whereas LINGO-1 expressed by oligodendrocyte progenitor cells was previously identifi

194 ds for enhancing myelination from endogenous oligodendrocyte progenitor cells, we screened a library

195 two populations of NG2 proteoglycan-positive oligodendrocyte progenitor cells were identified that ex

196 Oligodendrocyte progenitor cells were not decreased in d

197 se developing axon-free nerves, 25 to 33% of oligodendrocyte progenitor cells were proliferating.

198 rability of O4+ preoligodendrocytes, whereas oligodendrocyte progenitor cells were resistant to insul

199 o explore the mechanism of redistribution of oligodendrocyte progenitor cells with compensatory myeli

200 ng inflammatory injury, oligodendrocytes and oligodendrocyte progenitor cells within lesion sites are