ライフサイエンスコーパス: oligodeoxynucleotide

1 r cells produced IL-1beta in response to CpG oligodeoxynucleotide.

2 ile enterotoxin designated LT(R192G), or CpG oligodeoxynucleotide.

3 amina propria, which also increase after ISS-oligodeoxynucleotide.

4 as a function of varying amounts of a model oligodeoxynucleotide.

5 S, pertussis toxin (PTX), flagellin, and CpG oligodeoxynucleotide.

6 lowing stimulation with bacterial DNA or CpG oligodeoxynucleotide.

7 modifications of multideprotonated 6-20-mer oligodeoxynucleotides.

8 he pathogen-associated molecular pattern CpG oligodeoxynucleotides.

9 Os as compared to first-generation antisense oligodeoxynucleotides.

10 irectly targeted neurogranin using antisense oligodeoxynucleotides.

11 G) in codon 12 of the KRAS gene in synthetic oligodeoxynucleotides.

12 molecules by enzymatic cyclization of linear oligodeoxynucleotides.

13 ogues were synthesized and incorporated into oligodeoxynucleotides.

14 to multiple positions within single stranded oligodeoxynucleotides.

15 also accommodated the co-localization of CpG oligodeoxynucleotide 1826, a single-stranded synthetic D

16 eated with neurogranin antisense or mismatch oligodeoxynucleotides (2 microg/day, i.c.v.) for 3 conse

17 The solution structure of the oligodeoxynucleotide 5'-d(CTCGGCXCCATC)-3'.5'-d(GATGGCGC

18 restriction enzyme were compared, using the oligodeoxynucleotides 5'-d(CTCXGCGCCATC)-3'.5'-d(GATGGCG

19 modified oligodeoxynucleotides, a methylated oligodeoxynucleotide, a phosphorothioate-modified oligod

20 In vivo, CpG-oligodeoxynucleotide, a TLR9 agonist, given i.p. to ATF3

21 EPD of three modified oligodeoxynucleotides, a methylated oligodeoxynucleotide

22 activities of two-stranded K28 variants with oligodeoxynucleotide acceptor strands devoid of any 2OH

23 d intracytoplasmically and on the surface of oligodeoxynucleotide-activated normal B cells, was defic

24 n Qa-1(b)-deficient mice, or transfer of CpG-oligodeoxynucleotide-activated Qa-1(b)-deficient DC into

25 Triggering of TLR 9 with CpG oligodeoxynucleotides activates PDCs to up-regulate surf

26 itope-based vaccine admixed with a synthetic oligodeoxynucleotide adjuvant or loaded into yeast gluca

27 us, a previously unrecognized benefit of CpG oligodeoxynucleotides adjuvants is their ability to expa

28 Knockdown of CREB with antisense oligodeoxynucleotide against CREB reduced mechanical all

29 ivity) or knockdown of TNFRI using antisense oligodeoxynucleotide against TNFRI reduced mechanical al

30 ial role in DC responses to unmethylated CpG oligodeoxynucleotide: although responses to lipopolysacc

31 llowing stimulation with lipopolysaccharide, oligodeoxynucleotides, ammonium chloride, and interleuki

32 cytosine guanine dinucleotide (CpG)-enriched oligodeoxynucleotide, an agonist for the toll-like recep

33 phenotype reversal than the TLR agonists CpG-oligodeoxynucleotide and Gardiquimod.

34 vations were then validated in oxidations of oligodeoxynucleotide and lambda-DNA contexts that demons

35 lly stimulated IL-17 production, whereas CpG oligodeoxynucleotide and polyinosinic:polycytidylic acid

36 ned the energetics of ssDNA binding to short oligodeoxynucleotides and find that at moderate salt con

37 y may be a general feature of certain G-rich oligodeoxynucleotides and is associated with quadruplex

38 d with delivery of donors as single-stranded oligodeoxynucleotides and nucleases as messenger ribonuc

39 that process, we incorporated 4-OHEN-dC into oligodeoxynucleotides and used them as templates in prim

40 deoxynucleotide, a phosphorothioate-modified oligodeoxynucleotide, and an ethylated-oligodeoxynucleot

41 y signals, such as IFN-gamma, IFN-alpha, CpG oligodeoxynucleotides, and 4-1BB ligation.

42 ts were formed in single and double-stranded oligodeoxynucleotides, and these could be analyzed after

43 An antisense oligodeoxynucleotide annealing across the Lab site inhib

44 Intrathecal administration of oligodeoxynucleotide antisense against Drp1 produced a d

45 yperalgesia that is prevented by intrathecal oligodeoxynucleotide antisense to CD44 mRNA, which also

46 traganglion 8-bromo cAMP was prevented by an oligodeoxynucleotide antisense to mRNA for a transcripti

47 induced priming is prevented by intrathecal oligodeoxynucleotide antisense to the nuclear transcript

48 Spinal intrathecal administration of oligodeoxynucleotides antisense to TRPC1 and TRPC6, like

49 uced by spinal intrathecal administration of oligodeoxynucleotides antisense to TRPV4.

50 Similarly, oligodeoxynucleotide-antisense against COX-1 or COX-2, b

51 Antisense oligodeoxynucleotides (AONs) and short interfering RNAs

52 largely restored by use of a CpG-containing oligodeoxynucleotide as an adjuvant.

53 lelic knock-in clones, using single-stranded oligodeoxynucleotides as homologous templates, for inser

54 in some forms of neuropathic pain, antisense oligodeoxynucleotides (AS-ODNs) or mismatch ODNs (MM-ODN

55 explored using neutralizing mAbs, antisense oligodeoxynucleotides (AS-ODNs), and small interfering R

56 tance, we used a sequence-specific antisense oligodeoxynucleotide (ASO) to lower hepatic Scd1 express

57 The activity of a 20-mer antisense oligodeoxynucleotide (asODN) is transiently blocked by a

58 rmacological agents, Cx43-specific antisense oligodeoxynucleotides (asODNs) or dominant negative Cx43

59 Light-activated antisense oligodeoxynucleotides (asODNs) were developed to control

60 Coadministration of CpG-containing oligodeoxynucleotides at the time of infection overcame

61 gand LPS or the TLR9 ligand unmethylated CpG oligodeoxynucleotide before transient brain ischemia in

62 d to pathogen-derived motifs, CpG-containing oligodeoxynucleotides binding to toll-like receptor 9, w

63 of a TLR9 antagonist, known as a suppressive oligodeoxynucleotide, blocked tumor-induced temperature

64 nding phosphoramidites and incorporated into oligodeoxynucleotides by standard DNA chemistry.

65 Plasmids, RNA interference and antisense oligodeoxynucleotides can be readily introduced into the

66 r Epac1 or mice treated with Epac1 antisense oligodeoxynucleotides, chronic PGE2-induced hyperalgesia

67 rete, photogenerated C1'-radical in a DNA 2'-oligodeoxynucleotide cleanly generates the 2-deoxyribono

68 Moreover, binding of HMGB1 to class A CpG oligodeoxynucleotides considerably augmented cytokine pr

69 e the preparation and characterization of an oligodeoxynucleotide containing a CPD of a T(m)CG site,

70 n structure of the complex formed between an oligodeoxynucleotide containing a two-base bulge (5'-CCA

71 apsid-like particles upon incubation with an oligodeoxynucleotide containing immunostimulatory CpG mo

72 nd liver-activating protein) to biotinylated oligodeoxynucleotide containing the pI or pIV binding si

73 We tested treatment with an oligodeoxynucleotide containing unmethylated CpG motif (

74 a fully automated procedure for synthesising oligodeoxynucleotides containing 3'-PS linkages.

75 Oligodeoxynucleotides containing 3'-S-phosphorothiolate

76 r TAM-DNA adduct, site-specifically modified oligodeoxynucleotides containing a single diastereoisome

77 4-OHEN-dA adduct, site-specifically modified oligodeoxynucleotides containing a single diastereoisome

78 To test this, oligodeoxynucleotides containing a site-specific N(6)-dA

79 Using duplex oligodeoxynucleotides containing all possible three-nucl

80 We previously reported immunostimulatory oligodeoxynucleotides containing CpG motifs (CpG ODN) en

81 cells proliferate in response to stimulatory oligodeoxynucleotides containing CpG motifs, suggesting

82 d accuracy of the method were validated with oligodeoxynucleotides containing the 2-deoxyribonolacton

83 As discussed in this Review, short synthetic oligodeoxynucleotides containing these immune stimulator

84 chemotherapy plus intratumoral injection of oligodeoxynucleotides containing unmethylated C-G motifs

85 Oligodeoxynucleotides containing unmethylated CpG motifs

86 Adding synthetic oligodeoxynucleotides containing unmethylated CpG motifs

87 Synthetic oligodeoxynucleotides containing unmethylated CpG motifs

88 Oligodeoxynucleotides containing unmethylated cytidyl gu

89 the nucleoside, single-stranded, and duplex oligodeoxynucleotide contexts were monitored allowing me

90 The synthetic oligodeoxynucleotide CpG 7909, which contains unmethylat

91 CpG oligodeoxynucleotide (CpG ODN) cellular uptake into endo

92 ic cell efficiency, an immunostimulatory CpG oligodeoxynucleotide (CpG ODN) was combined with Ad5-mTR

93 (TLR9) agonist cytidine-phosphate-guanosine oligodeoxynucleotide (CpG) to determine effective IL-10

94 ading" lymphoma tumor cells with CG-enriched oligodeoxynucleotide (CpG), a ligand for the Toll-like r

95 with the well-established TLR-9 agonist CpG oligodeoxynucleotide (CpG), and study the participation

96 s included incomplete Freund's adjuvant, CpG oligodeoxynucleotide (CpG), and the HLA-A2-restricted an

97 ress TLR9 intracellularly and respond to CpG oligodeoxynucleotide (CpG-ODN) by producing IFN-gamma an

98 he TLR9 agonist cytosine-phosphate-guanosine oligodeoxynucleotide (CpG-ODN) to induce neuroinflammati

99 ll-like receptor 9 (TLR9) stimulation by CpG-oligodeoxynucleotide (CpG-ODN) was integrated into micro

100 This study examined the effect of CpG oligodeoxynucleotide (CpG-ODN), the TLR9 ligand, on poly

101 plasmid-expressing Flt3 ligand (pFL) and CpG oligodeoxynucleotides (CpG ODN) as a combined nasal adju

102 in vivo exposure of newborn B lymphocytes to oligodeoxynucleotides (CpG ODN) led to up-regulation of

103 protein (TRP)-2(180-188) and CpG-containing oligodeoxynucleotides (CpG ODN) to mice, growth of the T

104 the TLR9 ligand cytosine phosphate guanosine oligodeoxynucleotides (CpG ODN), and boosted 12 wk later

105 Cytosine-phosphorothioate-guanine oligodeoxynucleotides (CpG ODNs) are synthetic ODNs with

106 ation delivery of anti-PD-1 antibody and CpG oligodeoxynucleotides (CpG ODNs) has been demonstrated t

107 Activation of TLR9 by CpG-motif containing oligodeoxynucleotides (CpG ODNs) is preceded by agonist

108 anti-CD40 mAb (alphaCD40) and CpG-containing oligodeoxynucleotides (CpG) could exert immunotherapeuti

109 g B-CLL cells with TLR9 agonists, type B CpG oligodeoxynucleotides (CpG-B ODNs), induces significant

110 haperone, is highly efficient in binding CpG oligodeoxynucleotides (CpG-ODN), the microbial DNA mimet

111 TLR9 agonists, cytosine-phosphate-guanosine oligodeoxynucleotides (CpG-ODN), to investigate the role

112 CpG-oligodeoxynucleotides (CpG-ODNs) are potent immune stimu

113 GNP causes specific inhibition of TLR9 (CpG oligodeoxynucleotides; CpG-ODNs) signal in macrophages.

114 d the mice with peptides plus CpG-containing oligodeoxynucleotides (CpGs) in incomplete Freund adjuva

115 characterized by synthesizing the tridecamer oligodeoxynucleotide d(GCGTACXCATGCG) harboring Fapy-dG

116 ce or microRNAs) and DNA binding (e.g., with oligodeoxynucleotide decoys or pyrrole-imidazole polyami

117 Furthermore, vaccination with CpG-oligodeoxynucleotide decreases the number of T(reg) cell

118 stimuli, as the T(H)1-inducing adjuvant, CpG oligodeoxynucleotide, did not promote either c-Kit or Ja

119 the development of an engineered STAT3 decoy oligodeoxynucleotide (dODN) that is stable in serum, is

120 ve shown that mycobacterial antigens and CpG oligodeoxynucleotides downmodulate airway allergic infla

121 The structure of an oligodeoxynucleotide duplex containing a site-specific S

122 ion of a site-specific N2-dG-IQ adduct in an oligodeoxynucleotide duplex containing the iterated CG r

123 Synthetic oligodeoxynucleotide duplexes containing site-specific O

124 In addition, the TLR ligands LPS and CpG oligodeoxynucleotide enhanced the level of FcRn expressi

125 odes for SUR1 by phosphorothioated antisense oligodeoxynucleotide essentially eliminated capillary fr

126 cells by using anti-IgM, imiquimod, and CpG oligodeoxynucleotide for BCR, TLR7, and TLR9, respective

127 an injection of antisense or random-sequence oligodeoxynucleotide for VIP in the SCN and blood sample

128 After culturing PDC with VIP and CpG oligodeoxynucleotides for 48 h, expression of surface mo

129 ide (LPS) and cytosine-phospho-guanine (CpG) oligodeoxynucleotides for 48 h.

130 Lipofection of MNCs with antisense oligodeoxynucleotides for ERK-1/2 resulted in a 50% decl

131 ersed by intrathecal injections of antisense oligodeoxynucleotides for the cytoplasmic polyadenylatio

132 Subsequent CID of the charge-reduced oligodeoxynucleotides formed upon electron detachment, i

133 LR9 agonist cytosine-phosphate-guanine (CpG) oligodeoxynucleotide formulated in a squalene-based oil-

134 miRNA first templates the cyclization of an oligodeoxynucleotide from a linear precursor containing

135 introduced at position 7 or 12 of the 15-mer oligodeoxynucleotide GGTTGGTGTGGTTGG, known as thrombin-

136 products from the UVB irradiation of duplex oligodeoxynucleotides harboring a BrdU or its closely re

137 Although the efficacy of CpG oligodeoxynucleotides has been thought to depend on the

138 Targeting of c-Myb by antisense oligodeoxynucleotides has suggested that myeloid leukemi

139 acellular delivery and silencing activity of oligodeoxynucleotides have been essentially completely d

140 CpG oligodeoxynucleotides have been investigated in airway a

141 Because synthetic RNA analogues and CpG oligodeoxynucleotides have been safely used in clinical

142 d expressing Cas9/gRNA and a single-stranded oligodeoxynucleotide HDR donor template in vitro.

143 Stimulation with anti-micro, LPS, CpG oligodeoxynucleotide, HSV-1, or CTLA-4 Ig activates the

144 sin D, chloroquine, and an inhibitory G-rich oligodeoxynucleotide identify TLR9 as the receptor for M

145 e-guanine, respectively, in immunomodulatory oligodeoxynucleotides (IMOs).

146 s proliferation is blocked by inhibitory CpG oligodeoxynucleotides, implicating the TLR9 (or possibly

147 GN mice with connexin 43-specific antisense oligodeoxynucleotide improved functional and structural

148 agonistic anti-CD40 mAb (anti-CD40) and CpG-oligodeoxynucleotides in activating macrophages to induc

149 tion of the innate immune response using CpG oligodeoxynucleotides in combination with anti-TNF-alpha

150 Activation of DC using CpG-oligodeoxynucleotides in Qa-1(b)-deficient mice, or tran

151 TLR9) with cytosine-guanosine-containing DNA oligodeoxynucleotides in Tg2576 AD model transgenic mice

152 When stimulated with CpG-enriched oligodeoxynucleotides in vitro, PPs and spleen pDCs made

153 eotides targeting Notch3 or scramble control oligodeoxynucleotides in wild-type mice concomitant to d

154 IL-1beta but not CpG-oligodeoxynucleotides, increased lipid accumulation in h

155 at treatment with anti-CD3/CD28 Abs plus CpG oligodeoxynucleotides induces robust expression of IL-30

156 Blocking endogenous Per1 with antisense oligodeoxynucleotides inhibited GRP-induced increases in

157 ntrahippocampal injections of RhoA antisense oligodeoxynucleotides inhibited theta burst stimulation

158 E-seq), relies on capture of double-stranded oligodeoxynucleotides into DSBs.

159 Delivery of OPN antisense oligodeoxynucleotides into mouse skin wounds by release

160 ke effector nucleases (TALENs) and synthetic oligodeoxynucleotides into one-cell embryos.

161 dation, through infusion of Zif268 antisense oligodeoxynucleotides into the basolateral amygdala shor

162 A (dsDNA) translocation; however, if a short oligodeoxynucleotide is used to interrogate a longer ssD

163 elta1 proteins, or Cavalpha2delta1 antisense oligodeoxynucleotides led to a reversal of orofacial hyp

164 f scRPA-(dT)L complexes as a function of the oligodeoxynucleotide length, L.

165 Oligodeoxynucleotide libraries containing randomly incor

166 Here, we report on 11 synthetic oligodeoxynucleotide libraries of various base combinati

167 Upon stimulation with CpG oligodeoxynucleotides, ligands for Toll-like receptor (T

168 After treatment with CCL1 antisense oligodeoxynucleotides, M2bM disappeared in MLNs of irrad

169 inhibition of immune responses by regulatory oligodeoxynucleotides may be useful for the treatment of

170 protein via CRISPR-assisted, single-stranded oligodeoxynucleotide-mediated homology-directed repair r

171 nsolidation, as their blockade via antisense oligodeoxynucleotide-mediated knockdown leads to memory

172 features of direct mutagenesis by TALENs and oligodeoxynucleotides, minimal effort and high speed, ca

173 de-antisense against COX-1 or COX-2, but not oligodeoxynucleotide-mismatch, decreased their respectiv

174 e reduced experimentally, by using antisense oligodeoxynucleotides, mitotic activity in the retina de

175 V-melting experiments were conducted with 16 oligodeoxynucleotides modified by the carcinogen 2-amino

176 Immunization with CpG oligodeoxynucleotide-modified nanoparticles resulted in

177 recombinant TS protein combined with a ssDNA oligodeoxynucleotide (ODN) adjuvant containing unmethyla

178 er Quil A or with Montanide ISA 720 plus CpG oligodeoxynucleotide (ODN) and was observed in both inbr

179 hymine dimers, we have synthesized a decamer oligodeoxynucleotide (ODN) containing a cis-syn thymine

180 Treatment with an oligodeoxynucleotide (ODN) containing CPG motifs (CpG OD

181 nucleosides, while the Gh yield increased in oligodeoxynucleotide (ODN) contexts or at reduced pH.

182 (TGEV) or the Toll-like receptor 9 agonist, oligodeoxynucleotide (ODN) D19, was markedly reduced in

183 assay for a model phosphorothioate backbone oligodeoxynucleotide (ODN) drug (7692 amu) from rat plas

184 ugate formulated with adjuvants alum and CpG oligodeoxynucleotide (ODN) generated heroin "immunoantag

185 re, we utilized 6 for preparation of labeled oligodeoxynucleotide (ODN) probes based on MS2 and cycli

186 rts of apoptosis after B-CLL exposure to CpG oligodeoxynucleotide (ODN) raised questions about a cent

187 9 and CD62P surface expression and augmented oligodeoxynucleotide (ODN) sequestration and PLT clumpin

188 Mammalian telomeric oligodeoxynucleotide (ODN) significantly inhibited all f

189 ling approach to prepare SMDHs with multiple oligodeoxynucleotide (ODN) strands.

190 xpression was manipulated using an antisense oligodeoxynucleotide (ODN) strategy.

191 intra-LA infusion of an Arc/Arg3.1 antisense oligodeoxynucleotide (ODN) was observed to be anatomical

192 response by artificial stimulation with CpG oligodeoxynucleotide (ODN), a TLR9 agonist, would result

193 odulatory cytosine-phosphate-guanidine (CpG) oligodeoxynucleotide (ODN), a toll-like receptor 9 (TLR9

194 CPG 10101, a synthetic oligodeoxynucleotide (ODN), is a toll-like receptor 9 (T

195 Selective oligodeoxynucleotide (ODN)-mediated down-regulation of b

196 ersion system to systematically characterize oligodeoxynucleotide (ODN)-mediated PGE using Cas9 and i

197 In contrast, the TLR9 ligand [oligodeoxynucleotide (ODN)1826] stimulated sFlt-1 secret

198 om immunized mice to TLR9 and 4 agonists CpG oligodeoxynucleotides (ODN) and LPS.

199 Synthetic oligodeoxynucleotides (ODN) expressing "immunosuppressiv

200 Immunostimulatory CpG oligodeoxynucleotides (ODN) have proven effective as adj

201 CpG oligodeoxynucleotides (ODN) show promise as immunoprotec

202 These effects are mimicked by synthetic CpG oligodeoxynucleotides (ODN).

203 cultured with or without a TLR9 agonist (CpG oligodeoxynucleotide [ODN] 2006) for 2 d and then assess

204 Although vaginal application of CpG oligodeoxynucleotides (ODNs) and poly I:C has been shown

205 Unmethylated CpG-oligodeoxynucleotides (ODNs) are generally thought of as

206 Indeed, short U3 oligodeoxynucleotides (ODNs) based on these RNA sequence

207 bond, 8-nitrodG cannot be incorporated into oligodeoxynucleotides (ODNs) by chemical DNA synthesis a

208 Oligodeoxynucleotides (ODNs) complementary to the (CTG)(

209 Synthetic oligodeoxynucleotides (ODNs) comprised of the immunosupp

210 ated solid-phase synthesis of mixed-backbone oligodeoxynucleotides (ODNs) consisting of methylborane

211 A. fumigatus DNA and synthetic CpG-rich oligodeoxynucleotides (ODNs) containing sequences found

212 Oligodeoxynucleotides (ODNs) containing unmethylated CpG

213 Oligodeoxynucleotides (ODNs) containing unmethylated CpG

214 Among them, synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG

215 Here we prepared oligodeoxynucleotides (ODNs) harboring a 6-TG, 2-AP-6-SC

216 Specific knockdown of Arc using antisense oligodeoxynucleotides (ODNs) in DH or VH attenuated the

217 Both siRNA and antisense oligodeoxynucleotides (ODNs) inhibit the expression of a

218 tor 9 using CpG (cytosine-phosphate-guanine) oligodeoxynucleotides (ODNs) leads to cognitive improvem

219 synthesis and site-specific incorporation in oligodeoxynucleotides (ODNs) of an emissive deoxyuridine

220 PI 3-kinase), since inhibitors and antisense oligodeoxynucleotides (ODNs) of Src and PI 3-kinase sign

221 HIF-1alpha decoy oligodeoxynucleotides (ODNs) or scrambled ODNs were tran

222 Application of CpG oligodeoxynucleotides (ODNs) resulted in neutrophil and

223 Short synthetic oligodeoxynucleotides (ODNs) rich in CpG or GpG motifs h

224 CpG oligodeoxynucleotides (ODNs) signal through TLR9 to indu

225 Immune-enhancing CpG and non-CPG oligodeoxynucleotides (ODNs) stimulate Ag presentation b

226 is possibility, hydrogels were modified with oligodeoxynucleotides (ODNs) that provide a target for d

227 ity of the amide-coupling reaction to tether oligodeoxynucleotides (ODNs) to organic molecules and th

228 ion by small interference RNA (and antisense oligodeoxynucleotides (ODNs)) led to dose-dependent redu

229 st, class B CpG (cytosine-phosphate-guanine) oligodeoxynucleotides (ODNs), can reduce amyloid and tau

230 the effects of the TLR9-associated ligands, oligodeoxynucleotides (ODNs), on highly purified T lymph

231 Several G-rich oligodeoxynucleotides (ODNs), which are capable of formi

232 CpG oligodeoxynucleotides (ODNs), which mimic bacterial DNA,

233 e repressor, NRSF, was abolished using decoy oligodeoxynucleotides (ODNs).

234 stimulated them with combinations of IRM and oligodeoxynucleotides (ODNs).

235 talyzed click reaction and incorporated into oligodeoxynucleotides (ODNs).

236 results show that prior stimulation with CpG oligodeoxynucleotide or Escherichia coli DNA prevented:

237 LR7/9 activation with different types of CpG oligodeoxynucleotides or tick-borne encephalitis vaccine

238 lockade by intrathecal antibodies, antisense oligodeoxynucleotides, or inactivation of the TSP4 gene

239 The RNA is transcribed from PCR-amplified oligodeoxynucleotides originally synthesized on a microa

240 sly shown that intratumoral injection of CpG oligodeoxynucleotide plus systemic chemotherapy can indu

241 dize to target molecules, the binding of two oligodeoxynucleotide probes to RNA targets was measured

242 hosphate and tetanus toxoid in alum plus CpG-oligodeoxynucleotides produced high secondary titers of

243 of these cells, 2) activation of FC with CpG-oligodeoxynucleotide promotes CD4(+)25(-) T cell differe

244 ate that IL-12, IL-18, and TLR 9 agonist CpG oligodeoxynucleotides reduce the level of fusion-mediate

245 Conversely, treatment with TNFR2 antisense oligodeoxynucleotides reduced liver metastasis in wild-t

246 The RAGE ligand ODN2006, a synthetic oligodeoxynucleotide resembling pathogenic hypomethylate

247 annealing of the product with a ruthenylated oligodeoxynucleotide resulted in the capture of rutheniu

248 ified oligodeoxynucleotide, and an ethylated-oligodeoxynucleotide, resulted in specific and extensive

249 in (Lrp) co-crystallized with a short duplex oligodeoxynucleotide reveals a novel quaternary assembly

250 cognate Fapy-dG site-specifically within any oligodeoxynucleotide sequence.

251 Two seeding oligodeoxynucleotides, so-called oligoseeds, which encod

252 agent) linked to a phosphorothioate-modified oligodeoxynucleotide (sODN) complementary to c-fos mRNA

253 (AS) or sense (S) phosphorothioate-modified oligodeoxynucleotide (sODN) sequences that correspond to

254 p-9 mRNA activity [phosphorothioate-modified oligodeoxynucleotide (sODN)-mmp9] or a control probe wit

255 ONs) (15-20 nm) to phosphorothioate-modified oligodeoxynucleotides (sODNs) with sequence complementar

256 al Cas9 protein:crRNA:tracrRNA:single-strand oligodeoxynucleotide (ssODN) complex into mouse zygotes.

257 nucleoporation with a 70 nt single-stranded oligodeoxynucleotide (ssODN) correction template.

258 Here, we show that single-stranded oligodeoxynucleotides (ssODNs) containing a methyl-CpG m

259 The use of single-stranded oligodeoxynucleotides (ssODNs) has been demonstrated to

260 ploys an enriched library of single-stranded oligodeoxynucleotides (ssODNs) to profile complex biolog

261 inistration of the TLR9 agonist molecule CpG oligodeoxynucleotide stimulated protective immunity in L

262 ytes secrete IFN-gamma upon culture with CpG oligodeoxynucleotide-stimulated dendritic cells (DCs) fr

263 te sequencing was possible for virtually all oligodeoxynucleotides studied.

264 as been characterized in both nucleoside and oligodeoxynucleotide studies.

265 BL21 have been measured using 5'-fluorescent oligodeoxynucleotide substrates containing embedded ribo

266 hepsin B inhibition, and a G-rich inhibitory oligodeoxynucleotide supports the involvement of TLR9 in

267 An oligodeoxynucleotide targeting four nNOS isoforms given

268 We then administered antisense oligodeoxynucleotides targeting Notch3 or scramble contr

269 Oligodeoxynucleotide telomere models such as d[A(GGGTTA)

270 we showed that a variety of telomeric G-tail oligodeoxynucleotides (TG-ODNs) exhibited antiproliferat

271 It is a quadruplex-forming oligodeoxynucleotide that binds to nucleolin as an aptam

272 The approach uses an oligodeoxynucleotide that folds to a stem-loop with a TG

273 Using a series of oligodeoxynucleotides that mimic potential intermediates

274 Using site-specifically modified oligodeoxynucleotides that serve as a model for potentia

275 luding intravaginally applied CpG-containing oligodeoxynucleotides that stimulate toll-like receptor

276 48 (TLR7/8-L), or cytosine-phosphate-guanine oligodeoxynucleotide (TLR9-L) induced a rapid and robust

277 e investigated the effect of exposure to CpG oligodeoxynucleotides (TLR9 ligands) prior to neonatal r

278 However, administering antisense oligodeoxynucleotide to attenuate ET(A) receptor express

279 We investigated the ability of CpG-oligodeoxynucleotide to generate an anti-tumor CD8+ T-ce

280 hecal injection of a gene-specific antisense oligodeoxynucleotide to knock down the expression of eac

281 GuaUre-dR at defined positions in synthetic oligodeoxynucleotides to demonstrate that it is a potent

282 ne expression by administration of antisense oligodeoxynucleotides to hippocampal slices in vitro or

283 blotting, and chemical inhibitors/antisense oligodeoxynucleotides to signaling intermediates to asse

284 cofactor for TLR9 activation, delivering CpG-oligodeoxynucleotides to TLR9 in endolysosomes.

285 its NR1, NR2B, NR2D, and NR3A with antisense-oligodeoxynucleotide treatment in the DRG.

286 In oligodeoxynucleotides, two equilibrating FAPY species, s

287 ficient charge reduction of the deprotonated oligodeoxynucleotides via electron detachment, in additi

288 sing a mouse model, we deliver OPN antisense oligodeoxynucleotides via Pluronic gel to the surface of

289 The Tg-modified oligodeoxynucleotide was annealed with either 5'-d(A(13)

290 Furthermore, using antisense oligodeoxynucleotides, we show that Sry downregulation i

291 hibited, the colitis limiting effects of ISS-oligodeoxynucleotide were abrogated.

292 sequences, and synthetic poly(A) and poly T oligodeoxynucleotides were capable of activating pDCs in

293 Furthermore, phosphorothioated oligodeoxynucleotides were found to antagonize RIG-I sig

294 ymerases that may function in TLS past ICLs, oligodeoxynucleotides were synthesized containing site-s

295 Antisense phosphorothioate oligodeoxynucleotides were used to degrade the promoter-

296 One of them employs toehold-extended oligodeoxynucleotides whereas in the other one the switc

297 TLR 8, and cytosine-phosphate-guanine (CpG) oligodeoxynucleotides, which activate TLR 9-expressing c

298 sphoryl lipid A and cholesterol-modified CpG oligodeoxynucleotides, which can bind His-tagged protein

299 GED-0301 is an antisense oligodeoxynucleotide with a sequence complementary to th

300 Tm measurements of modified oligodeoxynucleotides with complementary RNA showed slig